locus-tag	class	description
GE023_RS00010	COG0592	DNA-directed DNA polymerase activity
GE023_RS00025	COG0012	GTP binding
GE023_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GE023_RS00040	COG2244	polysaccharide biosynthetic process
GE023_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GE023_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GE023_RS00075	COG0531	amino acid
GE023_RS00245	COG1792	Involved in formation and maintenance of cell shape
GE023_RS00255	COG3942	CHAP domain
GE023_RS00270	COG0416	fatty acid biosynthetic process
GE023_RS00275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE023_RS00280	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GE023_RS00285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GE023_RS00300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GE023_RS00305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GE023_RS00315	COG3942	CHAP domain
GE023_RS00320	COG0151	Belongs to the GarS family
GE023_RS00325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GE023_RS00335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GE023_RS00350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GE023_RS00365	COG1454	alcohol dehydrogenase
GE023_RS00365	COG1012	belongs to the aldehyde dehydrogenase family
GE023_RS00370	COG1064	alcohol dehydrogenase
GE023_RS00390	COG0051	transcription antitermination factor activity, RNA binding
GE023_RS00490	COG0200	Binds to the 23S rRNA
GE023_RS00495	COG0201	protein transport
GE023_RS00515	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GE023_RS00675	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GE023_RS00685	COG1252	NADH dehydrogenase
GE023_RS00690	COG1271	oxidase subunit
GE023_RS00695	COG1294	oxidase, subunit
GE023_RS00700	COG4988	ABC transporter
GE023_RS00705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GE023_RS00710	COG0142	geranyltranstransferase activity
GE023_RS00725	COG1121	(ABC) transporter
GE023_RS00730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GE023_RS00740	COG0582	viral genome integration into host DNA
GE023_RS00805	COG4499	WXG100 protein secretion system (Wss), protein YukC
GE023_RS00805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE023_RS00825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GE023_RS00830	COG1459	type II secretion system
GE023_RS00835	COG4537	Required for transformation and DNA binding
GE023_RS00860	COG2890	protein-(glutamine-N5) methyltransferase activity
GE023_RS00885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE023_RS00890	COG1363	Peptidase, m42
GE023_RS00900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE023_RS00905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GE023_RS00920	COG1428	Deoxynucleoside kinase
GE023_RS00925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GE023_RS00970	COG2031	fatty acid transporter
GE023_RS00980	COG0183	Belongs to the thiolase family
GE023_RS00985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GE023_RS01000	COG0251	oxidation-reduction process
GE023_RS01015	COG1269	ATP hydrolysis coupled proton transport
GE023_RS01020	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GE023_RS01030	COG1527	subunit (C
GE023_RS01035	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
GE023_RS01070	COG1744	ABC transporter substrate-binding protein PnrA-like
GE023_RS01075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GE023_RS01080	COG1349	DNA-binding transcription factor activity
GE023_RS01085	COG2390	Transcriptional regulator
GE023_RS01090	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE023_RS01095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE023_RS01100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE023_RS01105	COG1882	Formate acetyltransferase
GE023_RS01115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE023_RS01115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE023_RS01115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE023_RS01120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE023_RS01125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE023_RS01130	COG1882	Formate acetyltransferase
GE023_RS01135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GE023_RS01150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GE023_RS01180	COG3655	Transcriptional regulator
GE023_RS01195	COG2205	protein histidine kinase activity
GE023_RS01200	COG0745	RESPONSE REGULATOR receiver
GE023_RS01210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GE023_RS01215	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GE023_RS01220	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GE023_RS01255	COG2207	Transcriptional regulator
GE023_RS01265	COG1175	transmembrane transport
GE023_RS01270	COG0395	ABC-type sugar transport system, permease component
GE023_RS01285	COG2017	converts alpha-aldose to the beta-anomer
GE023_RS01290	COG1609	Transcriptional regulator
GE023_RS01295	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GE023_RS01300	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GE023_RS01305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GE023_RS01335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GE023_RS01340	COG0512	Glutamine amidotransferase of anthranilate synthase
GE023_RS01345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GE023_RS01350	COG0154	amidase activity
GE023_RS01365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GE023_RS01370	COG1609	Transcriptional regulator
GE023_RS01375	COG1263	PTS System
GE023_RS01375	COG2190	(PTS) system
GE023_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE023_RS01385	COG1363	Peptidase, m42
GE023_RS01420	COG3842	ATPase activity
GE023_RS01430	COG1523	belongs to the glycosyl hydrolase 13 family
GE023_RS01440	COG1862	Preprotein translocase
GE023_RS01450	COG4589	Belongs to the CDS family
GE023_RS01475	COG1846	Transcriptional regulator
GE023_RS01515	COG1126	abc transporter atp-binding protein
GE023_RS01535	COG3037	sugar-specific permease SgaT UlaA
GE023_RS01540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GE023_RS01555	COG1045	serine acetyltransferase
GE023_RS01570	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GE023_RS01585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE023_RS01605	COG1476	TRANSCRIPTIONal
GE023_RS01610	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GE023_RS01745	COG0351	phosphomethylpyrimidine kinase
GE023_RS01750	COG4720	Psort location CytoplasmicMembrane, score
GE023_RS01760	COG0668	transmembrane transport
GE023_RS01765	COG0544	peptidyl-prolyl cis-trans isomerase activity
GE023_RS01770	COG3343	RNA polymerase activity
GE023_RS01785	COG3279	Response regulator of the LytR AlgR family
GE023_RS01795	COG1346	cytolysis
GE023_RS01830	COG1461	Dihydroxyacetone kinase
GE023_RS01850	COG0765	amino acid transport
GE023_RS01865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GE023_RS01875	COG0719	Fe-S assembly protein
GE023_RS01880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GE023_RS01900	COG1686	Belongs to the peptidase S11 family
GE023_RS01905	COG1686	Belongs to the peptidase S11 family
GE023_RS01910	COG4166	transmembrane transport
GE023_RS01915	COG0601	transmembrane transport
GE023_RS01920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE023_RS01925	COG0444	Belongs to the ABC transporter superfamily
GE023_RS02020	COG0383	alpha-mannosidase activity
GE023_RS02040	COG2723	6-phospho-beta-galactosidase activity
GE023_RS02060	COG1175	transmembrane transport
GE023_RS02065	COG0395	ABC-type sugar transport system, permease component
GE023_RS02080	COG2972	Histidine kinase
GE023_RS02085	COG4753	response regulator
GE023_RS02085	COG2207	Transcriptional regulator
GE023_RS02090	COG3250	beta-galactosidase activity
GE023_RS02105	COG1605	Chorismate mutase
GE023_RS02105	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GE023_RS02145	COG4509	Sortase family
GE023_RS02180	COG0534	Mate efflux family protein
GE023_RS02200	COG0346	lactoylglutathione lyase activity
GE023_RS02240	COG1518	maintenance of DNA repeat elements
GE023_RS02245	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GE023_RS02250	COG0673	inositol 2-dehydrogenase activity
GE023_RS02255	COG0785	Cytochrome C biogenesis protein
GE023_RS02260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE023_RS02275	COG2972	Histidine kinase
GE023_RS02300	COG2235	arginine
GE023_RS02305	COG0454	-acetyltransferase
GE023_RS02315	COG1288	antiporter activity
GE023_RS02320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE023_RS02325	COG0549	Belongs to the carbamate kinase family
GE023_RS02335	COG0742	ribosomal rna small subunit methyltransferase
GE023_RS02345	COG3480	Lon protease (S16) C-terminal proteolytic domain
GE023_RS02355	COG1609	Transcriptional regulator
GE023_RS02360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GE023_RS02365	COG1869	D-ribose catabolic process
GE023_RS02375	COG1172	Belongs to the binding-protein-dependent transport system permease family
GE023_RS02380	COG1879	ABC-type sugar transport system periplasmic component
GE023_RS02385	COG4470	Protein conserved in bacteria
GE023_RS02390	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GE023_RS02400	COG1132	(ABC) transporter
GE023_RS02405	COG1132	(ABC) transporter
GE023_RS02410	COG0783	Belongs to the Dps family
GE023_RS02420	COG1940	carbohydrate kinase activity
GE023_RS02470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GE023_RS02490	COG3599	regulation of cell shape
GE023_RS02510	COG0542	response to heat
GE023_RS02515	COG4703	Protein of unknown function (DUF1797)
GE023_RS02520	COG0765	amino acid transport
GE023_RS02540	COG1378	Sugar-specific transcriptional regulator TrmB
GE023_RS02555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GE023_RS02565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GE023_RS02585	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GE023_RS02590	COG1438	arginine binding
GE023_RS02595	COG0497	DNA recombination
GE023_RS02610	COG2755	lipolytic protein G-D-S-L family
GE023_RS02630	COG2217	Heavy metal translocating P-type atpase
GE023_RS02645	COG1827	regulation of RNA biosynthetic process
GE023_RS02655	COG2116	formate transmembrane transporter activity
GE023_RS02660	COG0768	penicillin binding
GE023_RS02675	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GE023_RS02695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GE023_RS02705	COG0513	Belongs to the DEAD box helicase family
GE023_RS02720	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GE023_RS02725	COG0204	Acyl-transferase
GE023_RS02730	COG1555	photosystem II stabilization
GE023_RS02730	COG1596	polysaccharide export
GE023_RS02735	COG2333	competence protein COMEC
GE023_RS02735	COG0658	competence protein
GE023_RS02770	COG1187	pseudouridine synthase activity
GE023_RS02800	COG0546	phosphoglycolate phosphatase activity
GE023_RS02810	COG2223	nitrite transmembrane transporter activity
GE023_RS02815	COG4122	O-methyltransferase activity
GE023_RS02830	COG1476	TRANSCRIPTIONal
GE023_RS02850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE023_RS02855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE023_RS02860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GE023_RS02875	COG1012	belongs to the aldehyde dehydrogenase family
GE023_RS02880	COG0726	polysaccharide deacetylase
GE023_RS02885	COG0513	Belongs to the DEAD box helicase family
GE023_RS02905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GE023_RS02915	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GE023_RS02915	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GE023_RS02940	COG2186	Transcriptional regulator
GE023_RS02950	COG4109	DRTGG domain
GE023_RS02975	COG1316	TRANSCRIPTIONal
GE023_RS03000	COG1464	Belongs to the NlpA lipoprotein family
GE023_RS03020	COG2814	Major facilitator Superfamily
GE023_RS03030	COG1187	pseudouridine synthase activity
GE023_RS03040	COG2309	aminopeptidase activity
GE023_RS03065	COG2723	6-phospho-beta-galactosidase activity
GE023_RS03075	COG3711	transcriptional antiterminator
GE023_RS03075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE023_RS03085	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE023_RS03095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE023_RS03100	COG1126	abc transporter atp-binding protein
GE023_RS03105	COG0765	amino acid transport
GE023_RS03110	COG0556	nucleotide-excision repair
GE023_RS03125	COG1696	Membrane protein involved in D-alanine export
GE023_RS03135	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GE023_RS03150	COG3833	ABC-type maltose transport systems, permease component
GE023_RS03155	COG1175	transmembrane transport
GE023_RS03160	COG2182	Extracellular solute-binding protein
GE023_RS03165	COG1609	Transcriptional regulator
GE023_RS03170	COG1640	4-alpha-glucanotransferase
GE023_RS03175	COG0058	SHG alpha-glucan phosphorylase activity
GE023_RS03220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GE023_RS03225	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GE023_RS03235	COG0300	oxidoreductase activity
GE023_RS03240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GE023_RS03240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GE023_RS03255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GE023_RS03260	COG2384	SAM-dependent methyltransferase
GE023_RS03275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE023_RS03280	COG0270	DNA (cytosine-5-)-methyltransferase activity
GE023_RS03385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GE023_RS03390	COG0542	response to heat
GE023_RS03450	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GE023_RS03455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GE023_RS03460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE023_RS03470	COG4409	exo-alpha-(2->6)-sialidase activity
GE023_RS03475	COG0673	inositol 2-dehydrogenase activity
GE023_RS03495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GE023_RS03545	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GE023_RS03555	COG1088	dTDP-glucose 4,6-dehydratase activity
GE023_RS03565	COG2706	6-phosphogluconolactonase activity
GE023_RS03570	COG1051	belongs to the nudix hydrolase family
GE023_RS03575	COG0628	permease
GE023_RS03580	COG0457	Tetratricopeptide repeat
GE023_RS03585	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GE023_RS03645	COG3620	sequence-specific DNA binding
GE023_RS03735	COG3942	CHAP domain
GE023_RS03735	COG1388	LysM domain
GE023_RS03780	COG3843	relaxase mobilization nuclease domain protein
GE023_RS03835	COG0488	(ABC) transporter
GE023_RS03840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GE023_RS03845	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE023_RS03845	COG0022	dehydrogenase e1 component
GE023_RS03850	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE023_RS03880	COG0095	Lipoate-protein ligase
GE023_RS03885	COG3442	glutamine amidotransferase
GE023_RS03890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GE023_RS03895	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GE023_RS03915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GE023_RS03925	COG0647	UMP catabolic process
GE023_RS03940	COG1518	maintenance of DNA repeat elements
GE023_RS03945	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GE023_RS03985	COG3715	PTS system
GE023_RS03990	COG3716	PTS system mannose fructose sorbose family IID component
GE023_RS03995	COG2972	Histidine kinase
GE023_RS04000	COG2207	Transcriptional regulator
GE023_RS04000	COG4753	response regulator
GE023_RS04005	COG1840	ABC-type Fe3 transport system, periplasmic component
GE023_RS04020	COG1011	Hydrolase
GE023_RS04025	COG1012	belongs to the aldehyde dehydrogenase family
GE023_RS04040	COG0028	Belongs to the TPP enzyme family
GE023_RS04050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE023_RS04075	COG0398	Pfam SNARE associated Golgi protein
GE023_RS04085	COG1131	(ABC) transporter
GE023_RS04090	COG1725	Transcriptional regulator
GE023_RS04105	COG0469	pyruvate kinase activity
GE023_RS04120	COG2824	Alkylphosphonate utilization operon protein PhnA
GE023_RS04125	COG0765	amino acid transport
GE023_RS04130	COG1126	abc transporter atp-binding protein
GE023_RS04135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE023_RS04145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GE023_RS04150	COG1115	amino acid carrier protein
GE023_RS04160	COG2261	transglycosylase associated protein
GE023_RS04200	COG1136	(ABC) transporter
GE023_RS04200	COG4591	ABC-type transport system involved in lipoprotein release permease component
GE023_RS04230	COG0196	riboflavin kinase activity
GE023_RS04245	COG0483	inositol monophosphate 1-phosphatase activity
GE023_RS04250	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GE023_RS04250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GE023_RS04260	COG0573	inorganic phosphate transmembrane transporter activity
GE023_RS04265	COG0581	inorganic phosphate transmembrane transporter activity
GE023_RS04280	COG0704	Plays a role in the regulation of phosphate uptake
GE023_RS04290	COG0745	RESPONSE REGULATOR receiver
GE023_RS04295	COG5002	protein histidine kinase activity
GE023_RS04310	COG2813	Specifically methylates the guanine in position
GE023_RS04315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GE023_RS04325	COG0295	cytidine deaminase activity
GE023_RS04330	COG1744	ABC transporter substrate-binding protein PnrA-like
GE023_RS04355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GE023_RS04360	COG4684	Psort location CytoplasmicMembrane, score
GE023_RS04365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GE023_RS04375	COG0095	Lipoate-protein ligase
GE023_RS04385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE023_RS04415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE023_RS04420	COG1328	CTP reductase activity
GE023_RS04420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GE023_RS04425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE023_RS04440	COG0488	(ABC) transporter
GE023_RS04460	COG1272	protein, Hemolysin III
GE023_RS04480	COG0758	DNA mediated transformation
GE023_RS04485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GE023_RS04520	COG1136	(ABC) transporter
GE023_RS04525	COG0577	efflux transmembrane transporter activity
GE023_RS04530	COG0745	RESPONSE REGULATOR receiver
GE023_RS04535	COG5002	protein histidine kinase activity
GE023_RS04545	COG1252	NADH dehydrogenase
GE023_RS04550	COG0142	geranyltranstransferase activity
GE023_RS04555	COG4939	FMN-binding domain protein
GE023_RS04585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GE023_RS04595	COG2188	Transcriptional regulator
GE023_RS04615	COG0803	Belongs to the bacterial solute-binding protein 9 family
GE023_RS04630	COG0803	Belongs to the bacterial solute-binding protein 9 family
GE023_RS04635	COG0346	lactoylglutathione lyase activity
GE023_RS04640	COG3764	Sortase (surface protein transpeptidase)
GE023_RS04690	COG2890	protein-(glutamine-N5) methyltransferase activity
GE023_RS04715	COG2233	PERMEase
GE023_RS04730	COG1174	glycine betaine transport
GE023_RS04745	COG4221	oxidoreductase activity
GE023_RS04750	COG0280	phosphate acetyltransferase
GE023_RS04755	COG0564	pseudouridine synthase activity
GE023_RS04765	COG2357	RelA SpoT domain protein
GE023_RS04780	COG1104	cysteine desulfurase activity
GE023_RS04800	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GE023_RS04810	COG0628	permease
GE023_RS04840	COG1177	transmembrane transport
GE023_RS04845	COG1176	ABC-type spermidine putrescine transport system, permease component I
GE023_RS04860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GE023_RS04875	COG0302	gtp cyclohydrolase
GE023_RS04880	COG0285	dihydrofolate synthase activity
GE023_RS04905	COG0726	polysaccharide deacetylase
GE023_RS04915	COG0539	negative regulation of cytoplasmic translation
GE023_RS04935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE023_RS04950	COG0187	DNA topoisomerase II activity
GE023_RS04970	COG0765	amino acid transport
GE023_RS04975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE023_RS05150	COG1783	phage Terminase large subunit
GE023_RS05220	COG0863	Belongs to the N(4) N(6)-methyltransferase family
GE023_RS05310	COG0582	viral genome integration into host DNA
GE023_RS05355	COG4974	Belongs to the 'phage' integrase family
GE023_RS05365	COG1396	sequence-specific DNA binding
GE023_RS05385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE023_RS05385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE023_RS05395	COG3711	transcriptional antiterminator
GE023_RS05400	COG3684	Belongs to the aldolase LacD family
GE023_RS05405	COG1105	Belongs to the carbohydrate kinase PfkB family
GE023_RS05410	COG0698	ribose 5-phosphate isomerase
GE023_RS05420	COG1349	DNA-binding transcription factor activity
GE023_RS05425	COG3843	relaxase mobilization nuclease domain protein
GE023_RS05470	COG2217	Heavy metal translocating P-type atpase
GE023_RS05475	COG2217	Heavy metal translocating P-type atpase
GE023_RS05515	COG1388	LysM domain
GE023_RS05515	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE023_RS05530	COG0640	Transcriptional regulator
GE023_RS05535	COG2217	Heavy metal translocating P-type atpase
GE023_RS05550	COG0842	Transport permease protein
GE023_RS05555	COG1131	(ABC) transporter
GE023_RS05565	COG0446	pyridine nucleotide-disulphide oxidoreductase
GE023_RS05735	COG0270	DNA (cytosine-5-)-methyltransferase activity
GE023_RS05800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GE023_RS05810	COG3425	synthase
GE023_RS05845	COG1132	(ABC) transporter
GE023_RS05850	COG1132	(ABC) transporter
GE023_RS05855	COG0737	Belongs to the 5'-nucleotidase family
GE023_RS05860	COG0242	peptide deformylase activity
GE023_RS05865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GE023_RS05870	COG0488	(ABC) transporter
GE023_RS05895	COG1388	LysM domain
GE023_RS05895	COG1705	Flagellar rod assembly protein muramidase FlgJ
GE023_RS05900	COG1388	LysM domain
GE023_RS05900	COG1705	Flagellar rod assembly protein muramidase FlgJ
GE023_RS05905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE023_RS05905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE023_RS05905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE023_RS05910	COG1105	Belongs to the carbohydrate kinase PfkB family
GE023_RS05915	COG1349	DNA-binding transcription factor activity
GE023_RS05945	COG1837	Belongs to the UPF0109 family
GE023_RS05955	COG0584	glycerophosphoryl diester phosphodiesterase
GE023_RS05965	COG0577	efflux transmembrane transporter activity
GE023_RS05970	COG1136	(ABC) transporter
GE023_RS06010	COG0564	pseudouridine synthase activity
GE023_RS06020	COG0583	DNA-binding transcription factor activity
GE023_RS06025	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GE023_RS06050	COG1104	cysteine desulfurase activity
GE023_RS06060	COG0285	dihydrofolate synthase activity
GE023_RS06065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE023_RS06085	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GE023_RS06090	COG1368	sulfuric ester hydrolase activity
GE023_RS06135	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE023_RS06150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GE023_RS06165	COG1216	Glycosyl transferase, family 2
GE023_RS06220	COG2151	metal-sulfur cluster biosynthetic enzyme
GE023_RS06225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GE023_RS06230	COG0358	DNA primase activity
GE023_RS06235	COG1970	mechanosensitive ion channel activity
GE023_RS06245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE023_RS06250	COG0436	Aminotransferase
GE023_RS06290	COG2801	Transposase and inactivated derivatives
GE023_RS06370	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GE023_RS06375	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GE023_RS06380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GE023_RS06385	COG1523	belongs to the glycosyl hydrolase 13 family
GE023_RS06390	COG1597	lipid kinase activity
GE023_RS06400	COG4708	membrane
GE023_RS06420	COG1131	(ABC) transporter
GE023_RS06490	COG0772	Belongs to the SEDS family
GE023_RS06505	COG0038	chloride channel
GE023_RS06515	COG0716	FMN binding
GE023_RS06530	COG2153	protein acetylation
GE023_RS06535	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GE023_RS06545	COG0582	viral genome integration into host DNA
GE023_RS06595	COG0791	NLP P60 protein
GE023_RS06595	COG0741	lytic transglycosylase activity
GE023_RS06615	COG4581	dead DEAH box helicase
GE023_RS06635	COG2946	Replication initiation factor
GE023_RS06650	COG1674	ftsk spoiiie
GE023_RS06700	COG3716	PTS system mannose fructose sorbose family IID component
GE023_RS06705	COG3715	PTS system
GE023_RS06730	COG2222	sugar isomerase
GE023_RS06735	COG2188	Transcriptional regulator
GE023_RS06775	COG0017	Asparaginyl-tRNA synthetase
GE023_RS06780	COG0436	Aminotransferase
GE023_RS06785	COG1199	ATP-dependent helicase activity
GE023_RS06785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GE023_RS06795	COG2177	Part of the ABC transporter FtsEX involved in
GE023_RS06800	COG2884	Cell division ATP-binding protein ftsE
GE023_RS06810	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GE023_RS06815	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GE023_RS06820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GE023_RS06845	COG0800	Aldolase
GE023_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
GE023_RS06865	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE023_RS06865	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE023_RS06875	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE023_RS06880	COG3715	PTS system
GE023_RS06885	COG3716	PTS system mannose fructose sorbose family IID component
GE023_RS06895	COG1609	Transcriptional regulator
GE023_RS06910	COG1078	dGTPase activity
GE023_RS06920	COG2348	transferase activity, transferring amino-acyl groups
GE023_RS06970	COG0772	Belongs to the SEDS family
GE023_RS06980	COG1164	Oligoendopeptidase f
GE023_RS06985	COG0386	Belongs to the glutathione peroxidase family
GE023_RS07010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GE023_RS07040	COG2801	Transposase and inactivated derivatives
GE023_RS07045	COG4443	Transcriptional Coactivator p15 (PC4)
GE023_RS07100	COG2183	response to ionizing radiation
GE023_RS07115	COG0701	Predicted permease
GE023_RS07120	COG3689	TIGRFAM TIGR03943 family protein
GE023_RS07130	COG1263	PTS System
GE023_RS07130	COG2190	(PTS) system
GE023_RS07130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE023_RS07135	COG3711	transcriptional antiterminator
GE023_RS07140	COG0477	Major facilitator Superfamily
GE023_RS07145	COG0552	protein localization to endoplasmic reticulum
GE023_RS07150	COG0561	phosphatase activity
GE023_RS07155	COG0561	phosphatase activity
GE023_RS07165	COG1196	nuclear chromosome segregation
GE023_RS07175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GE023_RS07180	COG5002	protein histidine kinase activity
GE023_RS07185	COG0745	RESPONSE REGULATOR receiver
GE023_RS07200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE023_RS07205	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GE023_RS07210	COG1461	Dihydroxyacetone kinase
GE023_RS07215	COG2376	Dihydroxyacetone kinase
GE023_RS07225	COG2376	Dihydroxyacetone kinase
GE023_RS07245	COG4555	ABC transporter
GE023_RS07255	COG0438	transferase activity, transferring glycosyl groups
GE023_RS07270	COG1609	Transcriptional regulator
GE023_RS07275	COG0006	proline dipeptidase activity
GE023_RS07280	COG0778	Nitroreductase
GE023_RS07285	COG0346	lactoylglutathione lyase activity
GE023_RS07290	COG0463	Glycosyl transferase, family 2
GE023_RS07300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GE023_RS07305	COG0557	exoribonuclease II activity
GE023_RS07320	COG2814	Major facilitator Superfamily
GE023_RS07325	COG0433	COG0433 Predicted ATPase
GE023_RS07335	COG1131	(ABC) transporter
GE023_RS07350	COG1396	sequence-specific DNA binding
GE023_RS07390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GE023_RS07400	COG1573	uracil-dna glycosylase
GE023_RS07405	COG1702	phosphate starvation-inducible protein PhoH
GE023_RS07495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GE023_RS07520	COG0673	inositol 2-dehydrogenase activity
GE023_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
GE023_RS07555	COG1114	Component of the transport system for branched-chain amino acids
GE023_RS07595	COG1304	FMN binding
GE023_RS07610	COG0708	Exodeoxyribonuclease III
GE023_RS07620	COG1609	Transcriptional regulator
GE023_RS07635	COG1393	Belongs to the ArsC family
GE023_RS07640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GE023_RS07670	COG1774	PSP1 C-terminal conserved region
GE023_RS07675	COG0470	DNA polymerase III
GE023_RS07710	COG2244	polysaccharide biosynthetic process
GE023_RS07720	COG1120	ATPase activity
GE023_RS07725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE023_RS07730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE023_RS07735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE023_RS07750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GE023_RS07755	COG1253	flavin adenine dinucleotide binding
GE023_RS07760	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GE023_RS07765	COG1242	4 iron, 4 sulfur cluster binding
GE023_RS07770	COG0671	phosphoesterase, PA-phosphatase related
GE023_RS07775	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GE023_RS07805	COG1187	pseudouridine synthase activity
GE023_RS07860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE023_RS07870	COG1254	Belongs to the acylphosphatase family
GE023_RS07885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GE023_RS07905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE023_RS07915	COG1484	DNA-dependent DNA replication
GE023_RS07925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GE023_RS07930	COG5002	protein histidine kinase activity
GE023_RS07935	COG0745	RESPONSE REGULATOR receiver
GE023_RS07945	COG0501	Belongs to the peptidase M48B family
GE023_RS07950	COG1704	LemA family
GE023_RS07960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE023_RS07965	COG0569	domain protein
GE023_RS07975	COG1114	Component of the transport system for branched-chain amino acids
GE023_RS07995	COG1464	Belongs to the NlpA lipoprotein family
GE023_RS08000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE023_RS08010	COG0789	Transcriptional regulator
GE023_RS08015	COG1323	Belongs to the UPF0348 family
GE023_RS08020	COG2226	methyltransferase
GE023_RS08025	COG0799	negative regulation of ribosome biogenesis
GE023_RS08035	COG1713	HD superfamily hydrolase involved in NAD metabolism
GE023_RS08045	COG1534	Rna-binding protein
GE023_RS08050	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GE023_RS08055	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GE023_RS08115	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GE023_RS08120	COG1739	Uncharacterized protein family UPF0029
GE023_RS08130	COG1098	S1 RNA binding domain
GE023_RS08140	COG2197	response regulator
GE023_RS08145	COG4585	Histidine kinase
GE023_RS08155	COG0515	serine threonine protein kinase
GE023_RS08155	COG2815	serine threonine protein kinase
GE023_RS08165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GE023_RS08165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GE023_RS08175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GE023_RS08195	COG0183	Belongs to the thiolase family
GE023_RS08210	COG0116	Belongs to the methyltransferase superfamily
GE023_RS08235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE023_RS08240	COG3579	cysteine-type endopeptidase activity
GE023_RS08250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GE023_RS08255	COG1113	amino acid transport
GE023_RS08270	COG1126	abc transporter atp-binding protein
GE023_RS08275	COG0765	amino acid transport
GE023_RS08285	COG0513	Belongs to the DEAD box helicase family
GE023_RS08295	COG0768	penicillin binding
GE023_RS08330	COG1131	(ABC) transporter
GE023_RS08355	COG0446	pyridine nucleotide-disulphide oxidoreductase
GE023_RS08360	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE023_RS08395	COG1755	Isoprenylcysteine carboxyl methyltransferase
GE023_RS08400	COG0656	L-ascorbic acid biosynthetic process
GE023_RS08410	COG1283	sodium-dependent phosphate transmembrane transporter activity
GE023_RS08430	COG0561	phosphatase activity
GE023_RS08435	COG2860	membrane
GE023_RS08455	COG1105	Belongs to the carbohydrate kinase PfkB family
GE023_RS08495	COG2217	Heavy metal translocating P-type atpase
GE023_RS08535	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GE023_RS08540	COG0195	Participates in both transcription termination and antitermination
GE023_RS08565	COG4473	ABC transporter
GE023_RS08570	COG1131	(ABC) transporter
GE023_RS08575	COG0537	adenosine 5'-monophosphoramidase activity
GE023_RS08585	COG1316	TRANSCRIPTIONal
GE023_RS08590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE023_RS08595	COG0802	atpase or kinase
GE023_RS08600	COG2252	PERMEase
GE023_RS08605	COG0561	phosphatase activity
GE023_RS08615	COG3715	PTS system
GE023_RS08620	COG3716	PTS system mannose fructose sorbose family IID component
GE023_RS08650	COG0439	Biotin carboxylase
GE023_RS08665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GE023_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
GE023_RS08675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GE023_RS08700	COG1024	Enoyl-CoA hydratase
GE023_RS08705	COG0484	heat shock protein binding
GE023_RS08720	COG1420	regulation of RNA biosynthetic process
GE023_RS08735	COG0588	phosphoglycerate mutase activity
GE023_RS08740	COG2261	transglycosylase associated protein
GE023_RS08745	COG0697	spore germination
GE023_RS08765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GE023_RS08765	COG0574	Belongs to the PEP-utilizing enzyme family
GE023_RS08770	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GE023_RS08775	COG0517	IMP dehydrogenase activity
GE023_RS08780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE023_RS08785	COG1335	isochorismatase
GE023_RS08795	COG0436	Aminotransferase
GE023_RS08805	COG0561	phosphatase activity
GE023_RS08810	COG0252	asparaginase activity
GE023_RS08815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GE023_RS08820	COG1129	ABC transporter
GE023_RS08835	COG1132	(ABC) transporter
GE023_RS08840	COG4988	ABC transporter
GE023_RS08845	COG1120	ATPase activity
GE023_RS08870	COG1388	LysM domain
GE023_RS08870	COG3942	CHAP domain
GE023_RS08890	COG1482	cell wall glycoprotein biosynthetic process
GE023_RS08895	COG1940	carbohydrate kinase activity
GE023_RS08905	COG1263	PTS System
GE023_RS08905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE023_RS08905	COG2190	(PTS) system
GE023_RS08910	COG1621	beta-fructofuranosidase activity
GE023_RS08915	COG1609	Transcriptional regulator
GE023_RS08935	COG2131	deaminase
GE023_RS08940	COG0006	proline dipeptidase activity
GE023_RS08985	COG1194	a g-specific adenine glycosylase
GE023_RS08990	COG3118	belongs to the thioredoxin family
GE023_RS08995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE023_RS09020	COG0681	Belongs to the peptidase S26 family
GE023_RS09025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GE023_RS09040	COG1882	Formate acetyltransferase
GE023_RS09050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE023_RS09065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE023_RS09110	COG0789	Transcriptional regulator
GE023_RS09125	COG2081	HI0933 family
GE023_RS09145	COG1214	PFAM Peptidase M22, glycoprotease
GE023_RS09160	COG4608	Belongs to the ABC transporter superfamily
GE023_RS09165	COG0444	Belongs to the ABC transporter superfamily
GE023_RS09170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE023_RS09175	COG0601	transmembrane transport
GE023_RS09180	COG4166	transmembrane transport
GE023_RS09185	COG0174	glutamine synthetase
GE023_RS09190	COG0789	Transcriptional regulator
GE023_RS09205	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GE023_RS09235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GE023_RS09250	COG1564	THIamine pyrophosphokinase
GE023_RS09265	COG2814	Major facilitator Superfamily
GE023_RS09275	COG1288	antiporter activity
GE023_RS09280	COG0549	Belongs to the carbamate kinase family
GE023_RS09285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GE023_RS09295	COG0784	Response regulator, receiver
GE023_RS09310	COG0084	hydrolase, TatD family'
GE023_RS09320	COG2814	Major facilitator Superfamily
GE023_RS09325	COG1335	isochorismatase
GE023_RS09335	COG1263	PTS System
GE023_RS09335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE023_RS09335	COG2190	(PTS) system
GE023_RS09455	COG0270	DNA (cytosine-5-)-methyltransferase activity
GE023_RS09535	COG0756	dUTP diphosphatase activity
GE023_RS09545	COG1132	(ABC) transporter
GE023_RS09550	COG1132	(ABC) transporter
GE023_RS09565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GE023_RS09570	COG0705	Rhomboid family
GE023_RS09570	COG0457	Tetratricopeptide repeat
GE023_RS09575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GE023_RS09630	COG3843	relaxase mobilization nuclease domain protein
GE023_RS09680	COG1388	LysM domain
GE023_RS09680	COG3942	CHAP domain
GE023_RS09735	COG3620	sequence-specific DNA binding
GE023_RS09785	COG1234	tRNA 3'-trailer cleavage
GE023_RS09790	COG1268	BioY protein
GE023_RS09800	COG0343	queuine tRNA-ribosyltransferase activity
GE023_RS09820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE023_RS09820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE023_RS09830	COG4175	Glycine betaine
GE023_RS09830	COG3448	diguanylate cyclase activity
GE023_RS09835	COG1597	lipid kinase activity
GE023_RS09855	COG1070	Carbohydrate kinase
GE023_RS09865	COG3775	system Galactitol-specific IIC component
GE023_RS09870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GE023_RS09880	COG1609	Transcriptional regulator
GE023_RS09890	COG3623	hexulose-6-phosphate isomerase
GE023_RS09915	COG0495	leucyl-tRNA aminoacylation
GE023_RS09940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE023_RS09955	COG0564	pseudouridine synthase activity
GE023_RS09970	COG0494	nUDIX hydrolase
GE023_RS09995	COG0542	response to heat
GE023_RS10000	COG4463	regulation of RNA biosynthetic process
GE023_RS10055	COG0346	lactoylglutathione lyase activity
GE023_RS10060	COG0346	lactoylglutathione lyase activity
GE023_RS10065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GE023_RS10080	COG0450	alkyl hydroperoxide reductase
GE023_RS10095	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GE023_RS10105	COG3404	Formiminotransferase-cyclodeaminase
GE023_RS10120	COG0531	amino acid
GE023_RS10160	COG3590	peptidase
GE023_RS10175	COG0602	queuosine metabolic process
GE023_RS10195	COG1328	CTP reductase activity
GE023_RS10215	COG4472	Bacterial protein of unknown function (DUF965)
GE023_RS10220	COG1393	Belongs to the ArsC family
GE023_RS10240	COG0519	Catalyzes the synthesis of GMP from XMP
GE023_RS10320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE023_RS10325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE023_RS10330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE023_RS10435	COG1511	domain protein
GE023_RS10555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GE023_RS10565	COG0305	Participates in initiation and elongation during chromosome replication
GE023_RS10600	COG1760	l-serine dehydratase
GE023_RS10605	COG1760	l-serine dehydratase
GE023_RS10615	COG0741	lytic transglycosylase activity
GE023_RS10635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GE023_RS10645	COG0612	Peptidase, M16
GE023_RS10650	COG0612	Peptidase, M16
GE023_RS10670	COG0488	(ABC) transporter
GE023_RS10675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE023_RS10685	COG0517	IMP dehydrogenase activity
GE023_RS10685	COG0516	GMP reductase activity
GE023_RS10730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE023_RS10735	COG1475	DNA binding