locus-tag	class	description
DEH83_RS00015	COG3064	Membrane
DEH83_RS00015	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEH83_RS00015	COG3583	domain protein
DEH83_RS00020	COG0438	transferase activity, transferring glycosyl groups
DEH83_RS00035	COG1937	Protein conserved in bacteria
DEH83_RS00040	COG0653	protein targeting
DEH83_RS00110	COG0419	ATPase involved in DNA repair
DEH83_RS00130	COG0542	response to heat
DEH83_RS00135	COG1396	sequence-specific DNA binding
DEH83_RS00165	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEH83_RS00180	COG2814	Major facilitator Superfamily
DEH83_RS00195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEH83_RS00205	COG3064	Membrane
DEH83_RS00205	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DEH83_RS00260	COG0222	ribosome binding
DEH83_RS00265	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEH83_RS00285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DEH83_RS00305	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DEH83_RS00315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DEH83_RS00320	COG4684	Psort location CytoplasmicMembrane, score
DEH83_RS00325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEH83_RS00335	COG1194	a g-specific adenine glycosylase
DEH83_RS00340	COG0280	phosphate acetyltransferase
DEH83_RS00345	COG0564	pseudouridine synthase activity
DEH83_RS00350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEH83_RS00355	COG2357	RelA SpoT domain protein
DEH83_RS00365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEH83_RS00370	COG1104	cysteine desulfurase activity
DEH83_RS00385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEH83_RS00390	COG2003	Belongs to the UPF0758 family
DEH83_RS00395	COG0704	Plays a role in the regulation of phosphate uptake
DEH83_RS00400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DEH83_RS00405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DEH83_RS00410	COG0581	inorganic phosphate transmembrane transporter activity
DEH83_RS00415	COG0573	inorganic phosphate transmembrane transporter activity
DEH83_RS00425	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DEH83_RS00425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEH83_RS00430	COG0483	inositol monophosphate 1-phosphatase activity
DEH83_RS00435	COG4476	Belongs to the UPF0223 family
DEH83_RS00440	COG1393	Belongs to the ArsC family
DEH83_RS00445	COG0196	riboflavin kinase activity
DEH83_RS00450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEH83_RS00475	COG0210	DNA helicase
DEH83_RS00480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DEH83_RS00760	COG0582	viral genome integration into host DNA
DEH83_RS00765	COG0469	pyruvate kinase activity
DEH83_RS00770	COG0205	6-phosphofructokinase activity
DEH83_RS00780	COG1725	Transcriptional regulator
DEH83_RS00785	COG1131	(ABC) transporter
DEH83_RS00795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DEH83_RS00795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DEH83_RS00810	COG0300	oxidoreductase activity
DEH83_RS00830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEH83_RS00835	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEH83_RS00845	COG0577	efflux transmembrane transporter activity
DEH83_RS00850	COG1136	(ABC) transporter
DEH83_RS00860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEH83_RS00870	COG1268	BioY protein
DEH83_RS00885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEH83_RS00885	COG0072	phenylalanine-tRNA ligase activity
DEH83_RS00900	COG0488	(ABC) transporter
DEH83_RS00905	COG0617	tRNA 3'-terminal CCA addition
DEH83_RS00910	COG1307	EDD domain protein, DegV family
DEH83_RS00920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEH83_RS00920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEH83_RS00920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEH83_RS00925	COG1105	Belongs to the carbohydrate kinase PfkB family
DEH83_RS00930	COG1349	DNA-binding transcription factor activity
DEH83_RS00940	COG0492	ferredoxin-NADP+ reductase activity
DEH83_RS00945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEH83_RS00965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEH83_RS00970	COG1346	cytolysis
DEH83_RS00975	COG1380	Effector of murein hydrolase LrgA
DEH83_RS00995	COG1132	(ABC) transporter
DEH83_RS01015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEH83_RS01035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEH83_RS01040	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEH83_RS01045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEH83_RS01050	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEH83_RS01055	COG0356	it plays a direct role in the translocation of protons across the membrane
DEH83_RS01065	COG0058	SHG alpha-glucan phosphorylase activity
DEH83_RS01070	COG0297	glycogen (starch) synthase activity
DEH83_RS01075	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEH83_RS01080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEH83_RS01085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEH83_RS01090	COG1074	ATP-dependent DNA helicase activity
DEH83_RS01095	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DEH83_RS01100	COG1668	transmembrane transport
DEH83_RS01105	COG4152	abc transporter atp-binding protein
DEH83_RS01110	COG4443	Transcriptional Coactivator p15 (PC4)
DEH83_RS01135	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DEH83_RS01140	COG3527	Alpha-acetolactate decarboxylase
DEH83_RS01145	COG0028	Belongs to the TPP enzyme family
DEH83_RS01155	COG0628	permease
DEH83_RS01160	COG5002	protein histidine kinase activity
DEH83_RS01160	COG3850	Histidine kinase
DEH83_RS01165	COG0745	RESPONSE REGULATOR receiver
DEH83_RS01170	COG2706	6-phosphogluconolactonase activity
DEH83_RS01195	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DEH83_RS01200	COG0187	DNA topoisomerase II activity
DEH83_RS01210	COG0693	protein deglycase activity
DEH83_RS01215	COG0772	Belongs to the SEDS family
DEH83_RS01225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DEH83_RS01225	COG1199	ATP-dependent helicase activity
DEH83_RS01235	COG2177	Part of the ABC transporter FtsEX involved in
DEH83_RS01240	COG2884	Cell division ATP-binding protein ftsE
DEH83_RS01275	COG1078	dGTPase activity
DEH83_RS01290	COG2348	transferase activity, transferring amino-acyl groups
DEH83_RS01305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DEH83_RS01315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEH83_RS01325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DEH83_RS01330	COG4122	O-methyltransferase activity
DEH83_RS01355	COG2211	Major facilitator Superfamily
DEH83_RS01365	COG0363	glucosamine-6-phosphate deaminase activity
DEH83_RS01370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DEH83_RS01375	COG1438	arginine binding
DEH83_RS01390	COG1309	transcriptional regulator
DEH83_RS01395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEH83_RS01400	COG1288	antiporter activity
DEH83_RS01405	COG0549	Belongs to the carbamate kinase family
DEH83_RS01410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEH83_RS01485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEH83_RS01490	COG2274	protein secretion by the type I secretion system
DEH83_RS01500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DEH83_RS01510	COG2996	Protein conserved in bacteria
DEH83_RS01515	COG0233	cytoplasmic translational termination
DEH83_RS01520	COG0528	UMP kinase activity
DEH83_RS01525	COG0081	regulation of translation
DEH83_RS01540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEH83_RS01545	COG0697	spore germination
DEH83_RS01545	COG1674	ftsk spoiiie
DEH83_RS01550	COG1983	PspC domain protein
DEH83_RS01555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEH83_RS01560	COG0488	(ABC) transporter
DEH83_RS01570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEH83_RS01585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEH83_RS01610	COG1028	Short-chain dehydrogenase reductase Sdr
DEH83_RS01640	COG0531	amino acid
DEH83_RS01645	COG0577	efflux transmembrane transporter activity
DEH83_RS01650	COG1136	(ABC) transporter
DEH83_RS01665	COG3279	Response regulator of the LytR AlgR family
DEH83_RS01680	COG0577	efflux transmembrane transporter activity
DEH83_RS01685	COG1136	(ABC) transporter
DEH83_RS01705	COG0745	RESPONSE REGULATOR receiver
DEH83_RS01715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEH83_RS01715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEH83_RS01735	COG0640	Transcriptional regulator
DEH83_RS01750	COG0708	Exodeoxyribonuclease III
DEH83_RS01755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DEH83_RS01760	COG1393	Belongs to the ArsC family
DEH83_RS01765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEH83_RS01775	COG4467	Involved in initiation control of chromosome replication
DEH83_RS01780	COG0470	DNA polymerase III
DEH83_RS01790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DEH83_RS01795	COG0517	IMP dehydrogenase activity
DEH83_RS01815	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEH83_RS01825	COG4471	UPF0298 protein
DEH83_RS01830	COG0740	serine-type endopeptidase activity
DEH83_RS01835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEH83_RS01840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEH83_RS01845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DEH83_RS01860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEH83_RS01885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEH83_RS01895	COG0366	Alpha amylase catalytic
DEH83_RS01900	COG1263	PTS System
DEH83_RS01900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEH83_RS01905	COG2188	Transcriptional regulator
DEH83_RS01910	COG1253	flavin adenine dinucleotide binding
DEH83_RS01920	COG0628	permease
DEH83_RS01930	COG3599	regulation of cell shape
DEH83_RS01945	COG1799	cell septum assembly
DEH83_RS01950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DEH83_RS01965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DEH83_RS01970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEH83_RS01975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEH83_RS01985	COG1217	gtp-binding protein TYPA
DEH83_RS01990	COG1187	pseudouridine synthase activity
DEH83_RS02010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DEH83_RS02020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DEH83_RS02025	COG4470	Protein conserved in bacteria
DEH83_RS02030	COG3480	Lon protease (S16) C-terminal proteolytic domain
DEH83_RS02035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEH83_RS02040	COG0742	ribosomal rna small subunit methyltransferase
DEH83_RS02050	COG1040	competence protein
DEH83_RS02055	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DEH83_RS02060	COG1739	Uncharacterized protein family UPF0029
DEH83_RS02075	COG0525	valine-tRNA ligase activity
DEH83_RS02105	COG0519	Catalyzes the synthesis of GMP from XMP
DEH83_RS02125	COG2070	2-Nitropropane dioxygenase
DEH83_RS02130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEH83_RS02135	COG3231	kanamycin kinase activity
DEH83_RS02140	COG2137	regulation of response to DNA damage stimulus
DEH83_RS02145	COG3557	Belongs to the UPF0374 family
DEH83_RS02155	COG1185	polyribonucleotide nucleotidyltransferase activity
DEH83_RS02180	COG0515	serine threonine protein kinase
DEH83_RS02180	COG2815	serine threonine protein kinase
DEH83_RS02185	COG0631	protein serine/threonine phosphatase activity
DEH83_RS02190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEH83_RS02190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEH83_RS02195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEH83_RS02205	COG1758	RNA polymerase activity
DEH83_RS02210	COG0194	GDP metabolic process
DEH83_RS02215	COG1418	mRNA catabolic process
DEH83_RS02225	COG3634	alkyl hydroperoxide reductase activity
DEH83_RS02230	COG0450	alkyl hydroperoxide reductase
DEH83_RS02240	COG0116	Belongs to the methyltransferase superfamily
DEH83_RS02250	COG3599	regulation of cell shape
DEH83_RS02255	COG4474	Belongs to the UPF0398 family
DEH83_RS02260	COG3331	DNA recombination
DEH83_RS02270	COG3579	cysteine-type endopeptidase activity
DEH83_RS02275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEH83_RS02280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DEH83_RS02285	COG1113	amino acid transport
DEH83_RS02290	COG0492	ferredoxin-NADP+ reductase activity
DEH83_RS02300	COG1126	abc transporter atp-binding protein
DEH83_RS02310	COG0513	Belongs to the DEAD box helicase family
DEH83_RS02315	COG1686	Belongs to the peptidase S11 family
DEH83_RS02325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEH83_RS02330	COG0719	Fe-S assembly protein
DEH83_RS02340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEH83_RS02345	COG4862	establishment of competence for transformation
DEH83_RS02350	COG1968	undecaprenyl-diphosphatase activity
DEH83_RS02360	COG0765	amino acid transport
DEH83_RS02365	COG1126	abc transporter atp-binding protein
DEH83_RS02390	COG1131	(ABC) transporter
DEH83_RS02450	COG1131	(ABC) transporter
DEH83_RS02455	COG1461	Dihydroxyacetone kinase
DEH83_RS02465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEH83_RS02485	COG0191	fructose-bisphosphate aldolase activity
DEH83_RS02495	COG4166	transmembrane transport
DEH83_RS02500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEH83_RS02505	COG0768	penicillin binding
DEH83_RS02515	COG0275	rRNA processing
DEH83_RS02525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DEH83_RS02540	COG0751	glycine-tRNA ligase activity
DEH83_RS02545	COG0752	glycyl-tRNA synthetase alpha subunit
DEH83_RS02575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DEH83_RS02595	COG0656	L-ascorbic acid biosynthetic process
DEH83_RS02610	COG1283	sodium-dependent phosphate transmembrane transporter activity
DEH83_RS02615	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEH83_RS02630	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DEH83_RS02635	COG0195	Participates in both transcription termination and antitermination
DEH83_RS02640	COG0779	Required for maturation of 30S ribosomal subunits
DEH83_RS02650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DEH83_RS02655	COG0510	thiamine kinase activity
DEH83_RS02665	COG1131	(ABC) transporter
DEH83_RS02670	COG0537	adenosine 5'-monophosphoramidase activity
DEH83_RS02680	COG1316	TRANSCRIPTIONal
DEH83_RS02690	COG0802	atpase or kinase
DEH83_RS02695	COG2252	PERMEase
DEH83_RS02705	COG0561	phosphatase activity
DEH83_RS02715	COG3715	PTS system
DEH83_RS02720	COG3716	PTS system mannose fructose sorbose family IID component
DEH83_RS02730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEH83_RS02735	COG0586	Pfam SNARE associated Golgi protein
DEH83_RS02740	COG0825	malonyl-CoA metabolic process
DEH83_RS02745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DEH83_RS02750	COG0439	Biotin carboxylase
DEH83_RS02755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DEH83_RS02765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEH83_RS02770	COG1028	Short-chain dehydrogenase reductase Sdr
DEH83_RS02775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DEH83_RS02780	COG2070	2-Nitropropane dioxygenase
DEH83_RS02790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEH83_RS02800	COG1024	Enoyl-CoA hydratase
DEH83_RS02805	COG0527	aspartate kinase activity
DEH83_RS02855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEH83_RS02860	COG0006	proline dipeptidase activity
DEH83_RS02885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEH83_RS02890	COG0629	single-stranded DNA binding
DEH83_RS02935	COG1122	ATPase activity
DEH83_RS02945	COG0366	Alpha amylase catalytic
DEH83_RS02950	COG1304	FMN binding
DEH83_RS02960	COG1876	peptidase activity
DEH83_RS02980	COG0561	phosphatase activity
DEH83_RS02990	COG0346	lactoylglutathione lyase activity
DEH83_RS03015	COG2190	(PTS) system
DEH83_RS03015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEH83_RS03015	COG1263	PTS System
DEH83_RS03020	COG1447	Phosphotransferase system cellobiose-specific component IIA
DEH83_RS03025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DEH83_RS03035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DEH83_RS03040	COG1940	carbohydrate kinase activity
DEH83_RS03045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEH83_RS03045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEH83_RS03050	COG0167	dihydroorotate dehydrogenase activity
DEH83_RS03055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DEH83_RS03065	COG0668	transmembrane transport
DEH83_RS03080	COG3118	belongs to the thioredoxin family
DEH83_RS03090	COG1193	negative regulation of DNA recombination
DEH83_RS03110	COG0681	Belongs to the peptidase S26 family
DEH83_RS03115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DEH83_RS03120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEH83_RS03125	COG1882	Formate acetyltransferase
DEH83_RS03140	COG3425	synthase
DEH83_RS03150	COG1304	FMN binding
DEH83_RS03170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEH83_RS03185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DEH83_RS03190	COG2936	dipeptidyl-peptidase activity
DEH83_RS03195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEH83_RS03200	COG0584	glycerophosphoryl diester phosphodiesterase
DEH83_RS03215	COG2081	HI0933 family
DEH83_RS03220	COG0789	Transcriptional regulator
DEH83_RS03240	COG1396	sequence-specific DNA binding
DEH83_RS03255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEH83_RS03265	COG1214	PFAM Peptidase M22, glycoprotease
DEH83_RS03285	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEH83_RS03290	COG0049	tRNA binding
DEH83_RS03295	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEH83_RS03305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEH83_RS03310	COG3481	metal-dependent phosphohydrolase, HD sub domain
DEH83_RS03320	COG1564	THIamine pyrophosphokinase
DEH83_RS03330	COG1162	GTPase activity
DEH83_RS03345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DEH83_RS03360	COG0084	hydrolase, TatD family'
DEH83_RS03365	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DEH83_RS03380	COG0706	membrane insertase activity
DEH83_RS03385	COG0594	ribonuclease P activity
DEH83_RS03395	COG0166	Belongs to the GPI family
DEH83_RS03440	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEH83_RS03470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DEH83_RS03475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEH83_RS03490	COG4463	regulation of RNA biosynthetic process
DEH83_RS03505	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEH83_RS03510	COG0052	Belongs to the universal ribosomal protein uS2 family
DEH83_RS03635	COG0582	viral genome integration into host DNA
DEH83_RS03710	COG1484	DNA-dependent DNA replication
DEH83_RS03720	COG0305	Participates in initiation and elongation during chromosome replication
DEH83_RS03760	COG1396	sequence-specific DNA binding
DEH83_RS03775	COG4974	Belongs to the 'phage' integrase family
DEH83_RS03795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEH83_RS03800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEH83_RS03805	COG0564	pseudouridine synthase activity
DEH83_RS03825	COG3443	Belongs to the bacterial solute-binding protein 9 family
DEH83_RS03825	COG0803	Belongs to the bacterial solute-binding protein 9 family
DEH83_RS03830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DEH83_RS03835	COG1121	(ABC) transporter
DEH83_RS03840	COG1846	Transcriptional regulator
DEH83_RS03890	COG1394	ATPase activity, coupled to movement of substances
DEH83_RS03895	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DEH83_RS03900	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DEH83_RS03910	COG1527	subunit (C
DEH83_RS03920	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEH83_RS03925	COG1269	ATP hydrolysis coupled proton transport
DEH83_RS03945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEH83_RS03955	COG2731	YhcH YjgK YiaL family protein
DEH83_RS03960	COG0395	ABC-type sugar transport system, permease component
DEH83_RS03965	COG1175	transmembrane transport
DEH83_RS03975	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DEH83_RS03980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEH83_RS03985	COG1012	belongs to the aldehyde dehydrogenase family
DEH83_RS03985	COG1454	alcohol dehydrogenase
DEH83_RS04000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEH83_RS04010	COG2255	four-way junction helicase activity
DEH83_RS04040	COG2746	aminoglycoside 3-N-acetyltransferase activity
DEH83_RS04065	COG2222	sugar isomerase
DEH83_RS04075	COG3716	PTS system mannose fructose sorbose family IID component
DEH83_RS04085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEH83_RS04100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DEH83_RS04105	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DEH83_RS04110	COG1461	Dihydroxyacetone kinase
DEH83_RS04115	COG2376	Dihydroxyacetone kinase
DEH83_RS04125	COG2376	Dihydroxyacetone kinase
DEH83_RS04130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEH83_RS04150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DEH83_RS04160	COG3942	CHAP domain
DEH83_RS04165	COG0138	bifunctional purine biosynthesis protein purh
DEH83_RS04175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DEH83_RS04180	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DEH83_RS04185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DEH83_RS04195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEH83_RS04200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DEH83_RS04205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEH83_RS04215	COG1381	Involved in DNA repair and RecF pathway recombination
DEH83_RS04220	COG0436	Aminotransferase
DEH83_RS04225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEH83_RS04230	COG3942	CHAP domain
DEH83_RS04240	COG1792	Involved in formation and maintenance of cell shape
DEH83_RS04365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEH83_RS04370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DEH83_RS04395	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DEH83_RS04400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DEH83_RS04405	COG0193	aminoacyl-tRNA hydrolase activity
DEH83_RS04410	COG0012	GTP binding
DEH83_RS04425	COG0592	DNA-directed DNA polymerase activity
DEH83_RS04435	COG1475	DNA binding
DEH83_RS04440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEH83_RS04445	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DEH83_RS04485	COG0488	(ABC) transporter
DEH83_RS04490	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEH83_RS04495	COG0149	triose-phosphate isomerase activity
DEH83_RS04500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DEH83_RS04505	COG0180	Tryptophanyl-tRNA synthetase
DEH83_RS04510	COG0516	GMP reductase activity
DEH83_RS04510	COG0517	IMP dehydrogenase activity
DEH83_RS04515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEH83_RS04525	COG0612	Peptidase, M16
DEH83_RS04530	COG0612	Peptidase, M16
DEH83_RS04540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEH83_RS04545	COG1122	ATPase activity
DEH83_RS04550	COG1122	ATPase activity
DEH83_RS04555	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEH83_RS04570	COG1760	l-serine dehydratase
DEH83_RS04575	COG1760	l-serine dehydratase
DEH83_RS04585	COG0482	sulfurtransferase activity
DEH83_RS04590	COG0445	tRNA wobble uridine modification
DEH83_RS04605	COG0305	Participates in initiation and elongation during chromosome replication
DEH83_RS04615	COG1011	Hydrolase
DEH83_RS04620	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEH83_RS04635	COG0561	phosphatase activity
DEH83_RS04705	COG1696	Membrane protein involved in D-alanine export
DEH83_RS04710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEH83_RS04715	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DEH83_RS04720	COG0561	phosphatase activity
DEH83_RS04735	COG2807	transmembrane transport
DEH83_RS04765	COG0582	viral genome integration into host DNA
DEH83_RS04780	COG1674	ftsk spoiiie
DEH83_RS04815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEH83_RS04840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DEH83_RS04845	COG1523	belongs to the glycosyl hydrolase 13 family
DEH83_RS04850	COG1609	Transcriptional regulator
DEH83_RS04855	COG5521	maltodextrose utilization protein MalA
DEH83_RS04860	COG3833	ABC-type maltose transport systems, permease component
DEH83_RS04865	COG1175	transmembrane transport
DEH83_RS04870	COG2182	Extracellular solute-binding protein
DEH83_RS04875	COG1640	4-alpha-glucanotransferase
DEH83_RS04880	COG0058	SHG alpha-glucan phosphorylase activity
DEH83_RS04890	COG1780	Probably involved in ribonucleotide reductase function
DEH83_RS04895	COG0018	arginyl-trna synthetase
DEH83_RS04900	COG1438	arginine binding
DEH83_RS04905	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DEH83_RS04920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEH83_RS04925	COG3620	sequence-specific DNA binding
DEH83_RS04930	COG0632	four-way junction helicase activity
DEH83_RS04935	COG2818	Glycosylase
DEH83_RS04940	COG1266	CAAX protease self-immunity
DEH83_RS04955	COG1546	Belongs to the CinA family
DEH83_RS04955	COG1058	Belongs to the CinA family
DEH83_RS04960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEH83_RS04965	COG1393	Belongs to the ArsC family
DEH83_RS04980	COG4472	Bacterial protein of unknown function (DUF965)
DEH83_RS04985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEH83_RS04990	COG3906	Belongs to the UPF0473 family
DEH83_RS04995	COG0285	dihydrofolate synthase activity
DEH83_RS05015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEH83_RS05045	COG0602	queuosine metabolic process
DEH83_RS05055	COG4464	protein tyrosine phosphatase activity
DEH83_RS05060	COG3944	biosynthesis protein
DEH83_RS05065	COG0489	protein tyrosine kinase activity
DEH83_RS05085	COG1045	serine acetyltransferase
DEH83_RS05090	COG1442	glycosyl transferase family 8
DEH83_RS05090	COG1216	Glycosyl transferase, family 2
DEH83_RS05095	COG4641	Protein conserved in bacteria
DEH83_RS05095	COG0438	transferase activity, transferring glycosyl groups
DEH83_RS05130	COG5002	protein histidine kinase activity
DEH83_RS05140	COG2190	(PTS) system
DEH83_RS05140	COG1263	PTS System
DEH83_RS05140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEH83_RS05150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEH83_RS05150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEH83_RS05155	COG1832	CoA-binding protein
DEH83_RS05170	COG0343	queuine tRNA-ribosyltransferase activity
DEH83_RS05185	COG0051	transcription antitermination factor activity, RNA binding
DEH83_RS05190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEH83_RS05195	COG0088	Forms part of the polypeptide exit tunnel
DEH83_RS05200	COG0089	rRNA binding
DEH83_RS05205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEH83_RS05215	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEH83_RS05220	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEH83_RS05230	COG0255	Belongs to the universal ribosomal protein uL29 family
DEH83_RS05240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEH83_RS05245	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEH83_RS05250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEH83_RS05255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEH83_RS05260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEH83_RS05265	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEH83_RS05275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEH83_RS05280	COG1841	ribosomal large subunit assembly
DEH83_RS05285	COG0200	Binds to the 23S rRNA
DEH83_RS05290	COG0201	protein transport
DEH83_RS05295	COG0563	adenylate kinase activity
DEH83_RS05300	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEH83_RS05305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DEH83_RS05310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEH83_RS05315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEH83_RS05320	COG0202	RNA polymerase activity
DEH83_RS05325	COG0203	ribosomal protein L17
DEH83_RS05460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DEH83_RS05465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEH83_RS05480	COG0756	dUTP diphosphatase activity
DEH83_RS05495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEH83_RS05500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEH83_RS05510	COG2226	methyltransferase
DEH83_RS05520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEH83_RS05525	COG0085	RNA polymerase activity
DEH83_RS05530	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEH83_RS05540	COG0126	phosphoglycerate kinase activity
DEH83_RS05560	COG0789	Transcriptional regulator
DEH83_RS05565	COG0174	glutamine synthetase
DEH83_RS05575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DEH83_RS05580	COG1459	type II secretion system
DEH83_RS05585	COG4537	Required for transformation and DNA binding
DEH83_RS05615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEH83_RS05620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEH83_RS05630	COG3037	sugar-specific permease SgaT UlaA
DEH83_RS05640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEH83_RS05650	COG3623	hexulose-6-phosphate isomerase
DEH83_RS05670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DEH83_RS05685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEH83_RS05690	COG4589	Belongs to the CDS family
DEH83_RS05695	COG0750	zinc metalloprotease
DEH83_RS05700	COG0442	prolyl-tRNA aminoacylation
DEH83_RS05710	COG0285	dihydrofolate synthase activity
DEH83_RS05725	COG1363	Peptidase, m42
DEH83_RS05735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEH83_RS05740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEH83_RS05755	COG4585	Histidine kinase
DEH83_RS05760	COG2197	response regulator
DEH83_RS05780	COG3715	PTS system
DEH83_RS05785	COG3716	PTS system mannose fructose sorbose family IID component
DEH83_RS05795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEH83_RS05800	COG0459	protein refolding
DEH83_RS05810	COG1428	Deoxynucleoside kinase
DEH83_RS05815	COG1418	mRNA catabolic process
DEH83_RS05830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DEH83_RS05855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DEH83_RS05870	COG1490	D-aminoacyl-tRNA deacylase activity
DEH83_RS05895	COG3590	peptidase
DEH83_RS05915	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DEH83_RS05920	COG2176	DNA-directed DNA polymerase activity
DEH83_RS05930	COG0242	peptide deformylase activity
DEH83_RS05945	COG1187	pseudouridine synthase activity
DEH83_RS05960	COG1164	Oligoendopeptidase f
DEH83_RS05965	COG1185	polyribonucleotide nucleotidyltransferase activity
DEH83_RS05970	COG1045	serine acetyltransferase
DEH83_RS05980	COG0215	cysteine-tRNA ligase activity
DEH83_RS05985	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DEH83_RS05995	COG3842	ATPase activity
DEH83_RS06000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEH83_RS06015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEH83_RS06020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DEH83_RS06075	COG2184	nucleotidyltransferase activity
DEH83_RS06085	COG0534	Mate efflux family protein
DEH83_RS06100	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DEH83_RS06115	COG1215	transferase activity, transferring glycosyl groups
DEH83_RS06120	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DEH83_RS06130	COG5492	domain, Protein
DEH83_RS06155	COG1028	Short-chain dehydrogenase reductase Sdr
DEH83_RS06165	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DEH83_RS06170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEH83_RS06175	COG3715	PTS system
DEH83_RS06180	COG3716	PTS system mannose fructose sorbose family IID component
DEH83_RS06195	COG1609	Transcriptional regulator
DEH83_RS06200	COG3830	Belongs to the UPF0237 family
DEH83_RS06210	COG0588	phosphoglycerate mutase activity
DEH83_RS06220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEH83_RS06230	COG3037	sugar-specific permease SgaT UlaA
DEH83_RS06235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEH83_RS06240	COG1420	regulation of RNA biosynthetic process
DEH83_RS06245	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEH83_RS06255	COG0484	heat shock protein binding
DEH83_RS06265	COG0101	tRNA pseudouridine synthase activity
DEH83_RS06270	COG0351	phosphomethylpyrimidine kinase
DEH83_RS06275	COG4720	Psort location CytoplasmicMembrane, score
DEH83_RS06280	COG4475	Protein of unknown function (DUF436)
DEH83_RS06285	COG0544	peptidyl-prolyl cis-trans isomerase activity
DEH83_RS06290	COG3343	RNA polymerase activity
DEH83_RS06295	COG0504	CTP synthase activity
DEH83_RS06305	COG4166	transmembrane transport
DEH83_RS06310	COG4166	transmembrane transport
DEH83_RS06315	COG0601	transmembrane transport
DEH83_RS06320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEH83_RS06325	COG0444	Belongs to the ABC transporter superfamily
DEH83_RS06330	COG4608	Belongs to the ABC transporter superfamily
DEH83_RS06335	COG0561	phosphatase activity
DEH83_RS06340	COG1609	Transcriptional regulator
DEH83_RS06345	COG1621	beta-fructofuranosidase activity
DEH83_RS06350	COG1263	PTS System
DEH83_RS06350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEH83_RS06350	COG2190	(PTS) system
DEH83_RS06355	COG1940	carbohydrate kinase activity
DEH83_RS06360	COG0242	peptide deformylase activity
DEH83_RS06365	COG1902	pentaerythritol trinitrate reductase activity
DEH83_RS06380	COG1132	(ABC) transporter
DEH83_RS06385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DEH83_RS06390	COG1447	Phosphotransferase system cellobiose-specific component IIA
DEH83_RS06395	COG2723	6-phospho-beta-galactosidase activity
DEH83_RS06400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DEH83_RS06405	COG2188	Transcriptional regulator
DEH83_RS06410	COG1482	cell wall glycoprotein biosynthetic process
DEH83_RS06415	COG0531	amino acid
DEH83_RS06425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DEH83_RS06430	COG0736	holo-[acyl-carrier-protein] synthase activity
DEH83_RS06435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEH83_RS06440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DEH83_RS06445	COG0252	asparaginase activity
DEH83_RS06450	COG0561	phosphatase activity
DEH83_RS06455	COG0589	response to stress
DEH83_RS06460	COG0436	Aminotransferase
DEH83_RS06465	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DEH83_RS06470	COG1335	isochorismatase
DEH83_RS06475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DEH83_RS06480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEH83_RS06485	COG0154	amidase activity
DEH83_RS06500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEH83_RS06515	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DEH83_RS06520	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DEH83_RS06525	COG1534	Rna-binding protein
DEH83_RS06530	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEH83_RS06535	COG1713	HD superfamily hydrolase involved in NAD metabolism
DEH83_RS06540	COG0799	negative regulation of ribosome biogenesis
DEH83_RS06545	COG2226	methyltransferase
DEH83_RS06550	COG1323	Belongs to the UPF0348 family
DEH83_RS06560	COG1396	sequence-specific DNA binding
DEH83_RS06575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEH83_RS06580	COG1464	Belongs to the NlpA lipoprotein family
DEH83_RS06585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEH83_RS06590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEH83_RS06695	COG4720	Psort location CytoplasmicMembrane, score
DEH83_RS06725	COG1122	ATPase activity
DEH83_RS06735	COG4221	oxidoreductase activity
DEH83_RS06745	COG0357	Ribosomal RNA small subunit methyltransferase G
DEH83_RS06750	COG1704	LemA family
DEH83_RS06755	COG0501	Belongs to the peptidase M48B family
DEH83_RS06770	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DEH83_RS06775	COG0745	RESPONSE REGULATOR receiver
DEH83_RS06780	COG2190	(PTS) system
DEH83_RS06780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEH83_RS06780	COG1263	PTS System
DEH83_RS06790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEH83_RS06800	COG1484	DNA-dependent DNA replication
DEH83_RS06805	COG1160	GTP binding
DEH83_RS06810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEH83_RS06820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DEH83_RS06835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEH83_RS06855	COG1254	Belongs to the acylphosphatase family
DEH83_RS06860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEH83_RS06880	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DEH83_RS06885	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEH83_RS06895	COG0517	IMP dehydrogenase activity
DEH83_RS06900	COG4974	Belongs to the 'phage' integrase family
DEH83_RS06905	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEH83_RS06910	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEH83_RS06915	COG1187	pseudouridine synthase activity
DEH83_RS06925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DEH83_RS06930	COG0569	domain protein
DEH83_RS06940	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DEH83_RS06945	COG0671	phosphoesterase, PA-phosphatase related
DEH83_RS06955	COG1242	4 iron, 4 sulfur cluster binding
DEH83_RS06960	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DEH83_RS06980	COG2378	regulation of single-species biofilm formation
DEH83_RS06995	COG0542	response to heat
DEH83_RS07000	COG4703	Protein of unknown function (DUF1797)
DEH83_RS07030	COG1136	(ABC) transporter
DEH83_RS07035	COG0577	efflux transmembrane transporter activity
DEH83_RS07040	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEH83_RS07045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DEH83_RS07050	COG1570	exodeoxyribonuclease VII activity
DEH83_RS07055	COG1722	exodeoxyribonuclease VII activity
DEH83_RS07065	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DEH83_RS07070	COG1438	arginine binding
DEH83_RS07075	COG0497	DNA recombination
DEH83_RS07080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DEH83_RS07090	COG4604	ABC transporter, ATP-binding protein
DEH83_RS07095	COG4605	iron ion homeostasis
DEH83_RS07100	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEH83_RS07105	COG1307	EDD domain protein, DegV family
DEH83_RS07120	COG0588	phosphoglycerate mutase activity
DEH83_RS07125	COG0582	viral genome integration into host DNA
DEH83_RS07200	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
DEH83_RS07205	COG3620	sequence-specific DNA binding
DEH83_RS07215	COG0768	penicillin binding
DEH83_RS07220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEH83_RS07225	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEH83_RS07230	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DEH83_RS07255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DEH83_RS07270	COG0513	Belongs to the DEAD box helicase family
DEH83_RS07280	COG3684	Belongs to the aldolase LacD family
DEH83_RS07285	COG1349	DNA-binding transcription factor activity
DEH83_RS07315	COG3775	system Galactitol-specific IIC component
DEH83_RS07320	COG1105	Belongs to the carbohydrate kinase PfkB family
DEH83_RS07330	COG1755	Isoprenylcysteine carboxyl methyltransferase
DEH83_RS07340	COG2827	Endonuclease containing a URI domain
DEH83_RS07345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DEH83_RS07350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEH83_RS07370	COG1476	TRANSCRIPTIONal
DEH83_RS07385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEH83_RS07395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DEH83_RS07405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEH83_RS07410	COG0322	excinuclease ABC activity
DEH83_RS07425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEH83_RS07435	COG1573	uracil-dna glycosylase
DEH83_RS07445	COG1732	Glycine betaine
DEH83_RS07450	COG1125	glycine betaine transport
DEH83_RS07455	COG1063	alcohol dehydrogenase
DEH83_RS07465	COG0254	rRNA binding
DEH83_RS07470	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DEH83_RS07475	COG0716	FMN binding
DEH83_RS07495	COG1309	transcriptional regulator
DEH83_RS07515	COG1959	2 iron, 2 sulfur cluster binding
DEH83_RS07525	COG1349	DNA-binding transcription factor activity
DEH83_RS07535	COG1447	Phosphotransferase system cellobiose-specific component IIA
DEH83_RS07545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DEH83_RS07550	COG1882	Formate acetyltransferase
DEH83_RS07590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DEH83_RS07595	COG0406	alpha-ribazole phosphatase activity
DEH83_RS07615	COG0772	Belongs to the SEDS family
DEH83_RS07620	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DEH83_RS07625	COG1191	sigma factor activity
DEH83_RS07635	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEH83_RS07650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DEH83_RS07655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DEH83_RS07665	COG0813	purine-nucleoside phosphorylase activity
DEH83_RS07675	COG1368	sulfuric ester hydrolase activity
DEH83_RS07680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DEH83_RS07685	COG0710	3-dehydroquinate dehydratase activity
DEH83_RS07690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEH83_RS07695	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEH83_RS07700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEH83_RS07705	COG0730	response to heat
DEH83_RS07715	COG0287	Prephenate dehydrogenase
DEH83_RS07720	COG3679	Belongs to the UPF0342 family
DEH83_RS07725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DEH83_RS07735	COG0077	Prephenate dehydratase
DEH83_RS07745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEH83_RS07840	COG5444	nuclease activity
DEH83_RS07905	COG1349	DNA-binding transcription factor activity
DEH83_RS07910	COG0698	ribose 5-phosphate isomerase
DEH83_RS07915	COG0698	ribose 5-phosphate isomerase
DEH83_RS07920	COG1105	Belongs to the carbohydrate kinase PfkB family
DEH83_RS07925	COG3684	Belongs to the aldolase LacD family
DEH83_RS07930	COG3711	transcriptional antiterminator
DEH83_RS07955	COG1396	sequence-specific DNA binding
DEH83_RS07990	COG1216	Glycosyl transferase, family 2
DEH83_RS07990	COG1442	glycosyl transferase family 8
DEH83_RS08005	COG0463	Glycosyl transferase, family 2
DEH83_RS08010	COG1091	dTDP-4-dehydrorhamnose reductase activity
DEH83_RS08045	COG1368	sulfuric ester hydrolase activity
DEH83_RS08050	COG2384	SAM-dependent methyltransferase
DEH83_RS08055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEH83_RS08060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEH83_RS08065	COG0494	nUDIX hydrolase
DEH83_RS08070	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DEH83_RS08080	COG1088	dTDP-glucose 4,6-dehydratase activity
DEH83_RS08085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DEH83_RS08090	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DEH83_RS08095	COG0006	proline dipeptidase activity
DEH83_RS08100	COG1609	Transcriptional regulator
DEH83_RS08110	COG0438	transferase activity, transferring glycosyl groups
DEH83_RS08120	COG0745	RESPONSE REGULATOR receiver
DEH83_RS08125	COG5002	protein histidine kinase activity
DEH83_RS08130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DEH83_RS08140	COG0571	ribonuclease III activity
DEH83_RS08145	COG1196	nuclear chromosome segregation
DEH83_RS08150	COG0561	phosphatase activity
DEH83_RS08155	COG0561	phosphatase activity
DEH83_RS08160	COG0552	protein localization to endoplasmic reticulum
DEH83_RS08165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DEH83_RS08170	COG0477	Major facilitator Superfamily
DEH83_RS08175	COG3689	TIGRFAM TIGR03943 family protein
DEH83_RS08180	COG0701	Predicted permease
DEH83_RS08210	COG2183	response to ionizing radiation
DEH83_RS08230	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DEH83_RS08235	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEH83_RS08260	COG0826	peptidase U32
DEH83_RS08285	COG0488	(ABC) transporter
DEH83_RS08300	COG2814	Major facilitator Superfamily
DEH83_RS08310	COG3442	glutamine amidotransferase
DEH83_RS08315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DEH83_RS08320	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DEH83_RS08330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEH83_RS08335	COG0560	Phosphoserine phosphatase
DEH83_RS08360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DEH83_RS08370	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DEH83_RS08375	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEH83_RS08380	COG0513	Belongs to the DEAD box helicase family
DEH83_RS08385	COG0673	inositol 2-dehydrogenase activity
DEH83_RS08390	COG0572	uridine kinase
DEH83_RS08400	COG2195	Cleaves the N-terminal amino acid of tripeptides
DEH83_RS08405	COG0561	phosphatase activity
DEH83_RS08410	COG0481	GTPase activity
DEH83_RS08420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DEH83_RS08425	COG3842	ATPase activity
DEH83_RS08430	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEH83_RS08435	COG1177	transmembrane transport
DEH83_RS08450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEH83_RS08450	COG0574	Belongs to the PEP-utilizing enzyme family
DEH83_RS08460	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DEH83_RS08470	COG1104	cysteine desulfurase activity
DEH83_RS08475	COG0301	tRNA thio-modification
DEH83_RS08490	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DEH83_RS08500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEH83_RS08500	COG0425	Belongs to the sulfur carrier protein TusA family
DEH83_RS08510	COG1054	Belongs to the UPF0176 family
DEH83_RS08520	COG1937	Protein conserved in bacteria
DEH83_RS08530	COG0583	DNA-binding transcription factor activity
DEH83_RS08540	COG0564	pseudouridine synthase activity
DEH83_RS08545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEH83_RS08555	COG2824	Alkylphosphonate utilization operon protein PhnA
DEH83_RS08580	COG0038	chloride channel
DEH83_RS08585	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DEH83_RS08590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DEH83_RS08600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEH83_RS08605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DEH83_RS08610	COG1705	Flagellar rod assembly protein muramidase FlgJ
DEH83_RS08610	COG1388	LysM domain
DEH83_RS08625	COG1132	(ABC) transporter
DEH83_RS08630	COG0488	(ABC) transporter
DEH83_RS08645	COG0556	nucleotide-excision repair
DEH83_RS08650	COG0456	acetyltransferase
DEH83_RS08660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DEH83_RS08670	COG1051	belongs to the nudix hydrolase family
DEH83_RS08675	COG0647	UMP catabolic process
DEH83_RS08695	COG1660	Displays ATPase and GTPase activities
DEH83_RS08700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DEH83_RS08705	COG1481	regulation of sporulation
DEH83_RS08710	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEH83_RS08720	COG0540	Belongs to the ATCase OTCase family
DEH83_RS08725	COG0505	Belongs to the CarA family
DEH83_RS08730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEH83_RS08735	COG1940	carbohydrate kinase activity
DEH83_RS08770	COG1674	ftsk spoiiie
DEH83_RS08810	COG2184	nucleotidyltransferase activity
DEH83_RS08850	COG0745	RESPONSE REGULATOR receiver
DEH83_RS08855	COG5002	protein histidine kinase activity
DEH83_RS08865	COG4187	Peptidase family M20/M25/M40
DEH83_RS08880	COG1072	(Pantothenic acid kinase))
DEH83_RS08885	COG2813	Specifically methylates the guanine in position
DEH83_RS08895	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DEH83_RS08900	COG0295	cytidine deaminase activity
DEH83_RS08905	COG1744	ABC transporter substrate-binding protein PnrA-like
DEH83_RS08910	COG3845	ABC transporter
DEH83_RS08920	COG1079	Belongs to the binding-protein-dependent transport system permease family
DEH83_RS08925	COG1272	protein, Hemolysin III
DEH83_RS08935	COG3022	response to hydroperoxide
DEH83_RS08945	COG1846	Transcriptional regulator
DEH83_RS08955	COG0436	Aminotransferase
DEH83_RS08965	COG0017	Asparaginyl-tRNA synthetase
DEH83_RS08970	COG2814	Major facilitator Superfamily
DEH83_RS09020	COG2131	deaminase
DEH83_RS09030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DEH83_RS09035	COG0187	DNA topoisomerase II activity
DEH83_RS09055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEH83_RS09060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEH83_RS09080	COG0539	negative regulation of cytoplasmic translation
DEH83_RS09095	COG0039	L-malate dehydrogenase activity
DEH83_RS09100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEH83_RS09105	COG3764	Sortase (surface protein transpeptidase)
DEH83_RS09110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEH83_RS09115	COG1960	acyl-CoA dehydrogenase activity
DEH83_RS09120	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEH83_RS09125	COG0183	Belongs to the thiolase family
DEH83_RS09130	COG1024	Enoyl-CoA hydratase
DEH83_RS09135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DEH83_RS09140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DEH83_RS09145	COG0583	DNA-binding transcription factor activity
DEH83_RS09155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEH83_RS09160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DEH83_RS09165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEH83_RS09170	COG3711	transcriptional antiterminator
DEH83_RS09175	COG0110	maltose O-acetyltransferase activity
DEH83_RS09180	COG0758	DNA mediated transformation
DEH83_RS09185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEH83_RS09190	COG0135	phosphoribosylanthranilate isomerase activity
DEH83_RS09195	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DEH83_RS09215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DEH83_RS09220	COG0022	dehydrogenase e1 component
DEH83_RS09225	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEH83_RS09230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEH83_RS09235	COG0095	Lipoate-protein ligase
DEH83_RS09240	COG4974	Belongs to the 'phage' integrase family
DEH83_RS09245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DEH83_RS09255	COG2188	Transcriptional regulator
DEH83_RS09265	COG4974	Belongs to the 'phage' integrase family
DEH83_RS09315	COG0741	lytic transglycosylase activity
DEH83_RS09325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEH83_RS09330	COG0009	L-threonylcarbamoyladenylate synthase
DEH83_RS09335	COG2890	protein-(glutamine-N5) methyltransferase activity
DEH83_RS09340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEH83_RS09345	COG1435	thymidine kinase activity
DEH83_RS09350	COG1942	4-Oxalocrotonate Tautomerase
DEH83_RS09355	COG0534	Mate efflux family protein
DEH83_RS09365	COG0038	chloride channel
DEH83_RS09375	COG4555	ABC transporter
DEH83_RS09390	COG2972	Histidine kinase
DEH83_RS09395	COG2207	Transcriptional regulator
DEH83_RS09395	COG4753	response regulator
DEH83_RS09400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEH83_RS09400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEH83_RS09405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEH83_RS09410	COG0785	Cytochrome C biogenesis protein
DEH83_RS09420	COG2151	metal-sulfur cluster biosynthetic enzyme
DEH83_RS09425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEH83_RS09430	COG0358	DNA primase activity
DEH83_RS09435	COG1970	mechanosensitive ion channel activity
DEH83_RS09440	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DEH83_RS09455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEH83_RS09460	COG1132	(ABC) transporter
DEH83_RS09465	COG1132	(ABC) transporter
DEH83_RS09470	COG2315	Protein conserved in bacteria
DEH83_RS09475	COG3142	Participates in the control of copper homeostasis
DEH83_RS09490	COG1827	regulation of RNA biosynthetic process
DEH83_RS09495	COG1837	Belongs to the UPF0109 family
DEH83_RS09500	COG0228	four-way junction DNA binding
DEH83_RS09505	COG1523	belongs to the glycosyl hydrolase 13 family
DEH83_RS09510	COG1597	lipid kinase activity
DEH83_RS09515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEH83_RS09520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DEH83_RS09530	COG4708	membrane
DEH83_RS09535	COG2246	polysaccharide biosynthetic process
DEH83_RS09545	COG1846	Transcriptional regulator
DEH83_RS09555	COG0024	Methionine aminopeptidase
DEH83_RS09560	COG4109	DRTGG domain
DEH83_RS09570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEH83_RS09575	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEH83_RS09580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEH83_RS09585	COG1051	belongs to the nudix hydrolase family
DEH83_RS09590	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEH83_RS09605	COG2333	competence protein COMEC
DEH83_RS09605	COG0658	competence protein
DEH83_RS09615	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DEH83_RS09620	COG0557	exoribonuclease II activity
DEH83_RS09630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEH83_RS09635	COG2814	Major facilitator Superfamily
DEH83_RS09640	COG0237	dephospho-CoA kinase activity
DEH83_RS09645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEH83_RS09665	COG0494	nUDIX hydrolase
DEH83_RS09680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DEH83_RS09685	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEH83_RS09690	COG1132	(ABC) transporter
DEH83_RS09695	COG1132	(ABC) transporter
DEH83_RS09715	COG0686	Belongs to the AlaDH PNT family
DEH83_RS09740	COG4479	Belongs to the UPF0346 family
DEH83_RS09750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEH83_RS09760	COG0284	orotidine-5'-phosphate decarboxylase activity
DEH83_RS09765	COG0167	dihydroorotate dehydrogenase activity
DEH83_RS09770	COG0543	2 iron, 2 sulfur cluster binding
DEH83_RS09780	COG2814	Major facilitator Superfamily
DEH83_RS09800	COG0083	homoserine kinase activity
DEH83_RS09810	COG0726	polysaccharide deacetylase
DEH83_RS09820	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEH83_RS09835	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DEH83_RS09840	COG1609	Transcriptional regulator
DEH83_RS09845	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DEH83_RS09845	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DEH83_RS09855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEH83_RS09860	COG1956	GAF domain-containing protein
DEH83_RS09875	COG3443	Belongs to the bacterial solute-binding protein 9 family
DEH83_RS09875	COG0803	Belongs to the bacterial solute-binding protein 9 family
DEH83_RS09880	COG0336	Belongs to the RNA methyltransferase TrmD family
DEH83_RS09885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEH83_RS09900	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DEH83_RS09900	COG3583	domain protein
DEH83_RS09900	COG3064	Membrane
DEH83_RS09905	COG0438	transferase activity, transferring glycosyl groups
DEH83_RS09920	COG1937	Protein conserved in bacteria
DEH83_RS09925	COG0653	protein targeting
DEH83_RS09985	COG3843	relaxase mobilization nuclease domain protein
DEH83_RS10000	COG0419	ATPase involved in DNA repair