locus-tag	class	description
SCRE_RS00010	COG0592	DNA-directed DNA polymerase activity
SCRE_RS00025	COG0012	GTP binding
SCRE_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
SCRE_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SCRE_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SCRE_RS00055	COG0037	tRNA processing
SCRE_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SCRE_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SCRE_RS00185	COG1792	Involved in formation and maintenance of cell shape
SCRE_RS00195	COG3942	CHAP domain
SCRE_RS00200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SCRE_RS00205	COG0436	Aminotransferase
SCRE_RS00210	COG1381	Involved in DNA repair and RecF pathway recombination
SCRE_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCRE_RS00225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SCRE_RS00230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SCRE_RS00245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SCRE_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SCRE_RS00260	COG0138	bifunctional purine biosynthesis protein purh
SCRE_RS00265	COG3942	CHAP domain
SCRE_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SCRE_RS00300	COG1794	racemase activity, acting on amino acids and derivatives
SCRE_RS00305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SCRE_RS00310	COG2376	Dihydroxyacetone kinase
SCRE_RS00320	COG2376	Dihydroxyacetone kinase
SCRE_RS00325	COG1461	Dihydroxyacetone kinase
SCRE_RS00330	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SCRE_RS00335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SCRE_RS00350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCRE_RS00360	COG3716	PTS system mannose fructose sorbose family IID component
SCRE_RS00370	COG2222	sugar isomerase
SCRE_RS00390	COG2746	aminoglycoside 3-N-acetyltransferase activity
SCRE_RS00420	COG2255	four-way junction helicase activity
SCRE_RS00430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SCRE_RS00445	COG1012	belongs to the aldehyde dehydrogenase family
SCRE_RS00445	COG1454	alcohol dehydrogenase
SCRE_RS00455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SCRE_RS00460	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SCRE_RS00470	COG1175	transmembrane transport
SCRE_RS00475	COG0395	ABC-type sugar transport system, permease component
SCRE_RS00490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCRE_RS00510	COG1269	ATP hydrolysis coupled proton transport
SCRE_RS00515	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SCRE_RS00525	COG1527	subunit (C
SCRE_RS00535	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SCRE_RS00540	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
SCRE_RS00545	COG1394	ATPase activity, coupled to movement of substances
SCRE_RS00590	COG1846	Transcriptional regulator
SCRE_RS00595	COG1121	(ABC) transporter
SCRE_RS00600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SCRE_RS00605	COG0803	Belongs to the bacterial solute-binding protein 9 family
SCRE_RS00605	COG3443	Belongs to the bacterial solute-binding protein 9 family
SCRE_RS00625	COG0564	pseudouridine synthase activity
SCRE_RS00630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCRE_RS00655	COG0052	Belongs to the universal ribosomal protein uS2 family
SCRE_RS00660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SCRE_RS00670	COG4463	regulation of RNA biosynthetic process
SCRE_RS00685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SCRE_RS00690	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SCRE_RS00720	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SCRE_RS00760	COG0166	Belongs to the GPI family
SCRE_RS00765	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SCRE_RS00770	COG0594	ribonuclease P activity
SCRE_RS00775	COG0706	membrane insertase activity
SCRE_RS00905	COG3843	relaxase mobilization nuclease domain protein
SCRE_RS00935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SCRE_RS00940	COG0084	hydrolase, TatD family'
SCRE_RS00970	COG1162	GTPase activity
SCRE_RS00980	COG1564	THIamine pyrophosphokinase
SCRE_RS00990	COG3481	metal-dependent phosphohydrolase, HD sub domain
SCRE_RS00995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SCRE_RS01005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SCRE_RS01010	COG0049	tRNA binding
SCRE_RS01015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SCRE_RS01035	COG1214	PFAM Peptidase M22, glycoprotease
SCRE_RS01060	COG1396	sequence-specific DNA binding
SCRE_RS01075	COG0789	Transcriptional regulator
SCRE_RS01080	COG2081	HI0933 family
SCRE_RS01095	COG0584	glycerophosphoryl diester phosphodiesterase
SCRE_RS01100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SCRE_RS01105	COG2936	dipeptidyl-peptidase activity
SCRE_RS01110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SCRE_RS01125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SCRE_RS01145	COG1304	FMN binding
SCRE_RS01155	COG3425	synthase
SCRE_RS01170	COG1882	Formate acetyltransferase
SCRE_RS01180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SCRE_RS01185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SCRE_RS01190	COG0681	Belongs to the peptidase S26 family
SCRE_RS01210	COG1193	negative regulation of DNA recombination
SCRE_RS01220	COG3118	belongs to the thioredoxin family
SCRE_RS01235	COG0668	transmembrane transport
SCRE_RS01245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SCRE_RS01250	COG0167	dihydroorotate dehydrogenase activity
SCRE_RS01255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCRE_RS01255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCRE_RS01260	COG1940	carbohydrate kinase activity
SCRE_RS01265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCRE_RS01275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCRE_RS01280	COG1447	Phosphotransferase system cellobiose-specific component IIA
SCRE_RS01285	COG2190	(PTS) system
SCRE_RS01285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCRE_RS01285	COG1263	PTS System
SCRE_RS01310	COG0346	lactoylglutathione lyase activity
SCRE_RS01320	COG0561	phosphatase activity
SCRE_RS01335	COG3583	domain protein
SCRE_RS01335	COG3064	Membrane
SCRE_RS01335	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SCRE_RS01345	COG1876	peptidase activity
SCRE_RS01350	COG0028	Belongs to the TPP enzyme family
SCRE_RS01360	COG0366	Alpha amylase catalytic
SCRE_RS01370	COG1122	ATPase activity
SCRE_RS01385	COG1486	melibiose metabolic process
SCRE_RS01425	COG0629	single-stranded DNA binding
SCRE_RS01430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SCRE_RS01445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SCRE_RS01455	COG0006	proline dipeptidase activity
SCRE_RS01460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SCRE_RS01505	COG0527	aspartate kinase activity
SCRE_RS01510	COG1024	Enoyl-CoA hydratase
SCRE_RS01520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SCRE_RS01530	COG2070	2-Nitropropane dioxygenase
SCRE_RS01535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SCRE_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
SCRE_RS01545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SCRE_RS01555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SCRE_RS01560	COG0439	Biotin carboxylase
SCRE_RS01565	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SCRE_RS01570	COG0825	malonyl-CoA metabolic process
SCRE_RS01575	COG0586	Pfam SNARE associated Golgi protein
SCRE_RS01590	COG3716	PTS system mannose fructose sorbose family IID component
SCRE_RS01595	COG3715	PTS system
SCRE_RS01605	COG1064	alcohol dehydrogenase
SCRE_RS01610	COG0561	phosphatase activity
SCRE_RS01620	COG2252	PERMEase
SCRE_RS01625	COG0802	atpase or kinase
SCRE_RS01635	COG1316	TRANSCRIPTIONal
SCRE_RS01645	COG0537	adenosine 5'-monophosphoramidase activity
SCRE_RS01650	COG1131	(ABC) transporter
SCRE_RS01660	COG0510	thiamine kinase activity
SCRE_RS01665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SCRE_RS01675	COG0779	Required for maturation of 30S ribosomal subunits
SCRE_RS01680	COG0195	Participates in both transcription termination and antitermination
SCRE_RS01685	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SCRE_RS01700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SCRE_RS01705	COG1283	sodium-dependent phosphate transmembrane transporter activity
SCRE_RS01720	COG0656	L-ascorbic acid biosynthetic process
SCRE_RS01740	COG0752	glycyl-tRNA synthetase alpha subunit
SCRE_RS01745	COG0751	glycine-tRNA ligase activity
SCRE_RS01760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SCRE_RS01775	COG0275	rRNA processing
SCRE_RS01785	COG0768	penicillin binding
SCRE_RS01790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCRE_RS01805	COG0191	fructose-bisphosphate aldolase activity
SCRE_RS01825	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SCRE_RS01835	COG1461	Dihydroxyacetone kinase
SCRE_RS01855	COG2801	Transposase and inactivated derivatives
SCRE_RS01895	COG1131	(ABC) transporter
SCRE_RS01925	COG1126	abc transporter atp-binding protein
SCRE_RS01930	COG0765	amino acid transport
SCRE_RS01940	COG1968	undecaprenyl-diphosphatase activity
SCRE_RS01945	COG4862	establishment of competence for transformation
SCRE_RS01950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCRE_RS01960	COG0719	Fe-S assembly protein
SCRE_RS01965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SCRE_RS01975	COG1686	Belongs to the peptidase S11 family
SCRE_RS01980	COG0513	Belongs to the DEAD box helicase family
SCRE_RS01990	COG1126	abc transporter atp-binding protein
SCRE_RS02000	COG0492	ferredoxin-NADP+ reductase activity
SCRE_RS02005	COG1113	amino acid transport
SCRE_RS02010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SCRE_RS02015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SCRE_RS02020	COG3579	cysteine-type endopeptidase activity
SCRE_RS02025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCRE_RS02030	COG3331	DNA recombination
SCRE_RS02035	COG4474	Belongs to the UPF0398 family
SCRE_RS02040	COG3599	regulation of cell shape
SCRE_RS02045	COG0116	Belongs to the methyltransferase superfamily
SCRE_RS02055	COG0450	alkyl hydroperoxide reductase
SCRE_RS02060	COG3634	alkyl hydroperoxide reductase activity
SCRE_RS02070	COG1418	mRNA catabolic process
SCRE_RS02075	COG0194	GDP metabolic process
SCRE_RS02080	COG1758	RNA polymerase activity
SCRE_RS02085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SCRE_RS02090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SCRE_RS02100	COG0631	protein serine/threonine phosphatase activity
SCRE_RS02105	COG2815	serine threonine protein kinase
SCRE_RS02105	COG0515	serine threonine protein kinase
SCRE_RS02115	COG4585	Histidine kinase
SCRE_RS02130	COG1185	polyribonucleotide nucleotidyltransferase activity
SCRE_RS02140	COG3557	Belongs to the UPF0374 family
SCRE_RS02145	COG2137	regulation of response to DNA damage stimulus
SCRE_RS02150	COG3231	kanamycin kinase activity
SCRE_RS02155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SCRE_RS02160	COG2070	2-Nitropropane dioxygenase
SCRE_RS02180	COG0519	Catalyzes the synthesis of GMP from XMP
SCRE_RS02190	COG0525	valine-tRNA ligase activity
SCRE_RS02225	COG1739	Uncharacterized protein family UPF0029
SCRE_RS02230	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SCRE_RS02235	COG1040	competence protein
SCRE_RS02245	COG0742	ribosomal rna small subunit methyltransferase
SCRE_RS02250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SCRE_RS02255	COG3480	Lon protease (S16) C-terminal proteolytic domain
SCRE_RS02260	COG4470	Protein conserved in bacteria
SCRE_RS02265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SCRE_RS02275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SCRE_RS02305	COG0534	Mate efflux family protein
SCRE_RS02345	COG1217	gtp-binding protein TYPA
SCRE_RS02355	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SCRE_RS02360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SCRE_RS02365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SCRE_RS02375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SCRE_RS02380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SCRE_RS02385	COG1799	cell septum assembly
SCRE_RS02400	COG3599	regulation of cell shape
SCRE_RS02405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SCRE_RS02410	COG0628	permease
SCRE_RS02420	COG1253	flavin adenine dinucleotide binding
SCRE_RS02425	COG2188	Transcriptional regulator
SCRE_RS02435	COG0366	Alpha amylase catalytic
SCRE_RS02445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SCRE_RS02450	COG1227	inorganic diphosphatase activity
SCRE_RS02470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SCRE_RS02475	COG2244	polysaccharide biosynthetic process
SCRE_RS02480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SCRE_RS02485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SCRE_RS02490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SCRE_RS02495	COG0740	serine-type endopeptidase activity
SCRE_RS02510	COG0559	Belongs to the binding-protein-dependent transport system permease family
SCRE_RS02530	COG0517	IMP dehydrogenase activity
SCRE_RS02535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SCRE_RS02540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SCRE_RS02545	COG0470	DNA polymerase III
SCRE_RS02550	COG4467	Involved in initiation control of chromosome replication
SCRE_RS02560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SCRE_RS02565	COG1393	Belongs to the ArsC family
SCRE_RS02570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SCRE_RS02575	COG0708	Exodeoxyribonuclease III
SCRE_RS02590	COG0640	Transcriptional regulator
SCRE_RS02620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCRE_RS02620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCRE_RS02630	COG0745	RESPONSE REGULATOR receiver
SCRE_RS02645	COG1136	(ABC) transporter
SCRE_RS02650	COG0577	efflux transmembrane transporter activity
SCRE_RS02655	COG0531	amino acid
SCRE_RS02685	COG1028	Short-chain dehydrogenase reductase Sdr
SCRE_RS02705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SCRE_RS02720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SCRE_RS02730	COG0488	(ABC) transporter
SCRE_RS02735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SCRE_RS02745	COG1983	PspC domain protein
SCRE_RS02750	COG1674	ftsk spoiiie
SCRE_RS02750	COG0697	spore germination
SCRE_RS02755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SCRE_RS02770	COG0081	regulation of translation
SCRE_RS02775	COG0528	UMP kinase activity
SCRE_RS02780	COG0233	cytoplasmic translational termination
SCRE_RS02785	COG2996	Protein conserved in bacteria
SCRE_RS02800	COG0732	type I restriction modification DNA specificity domain
SCRE_RS02805	COG0732	type I restriction modification DNA specificity domain
SCRE_RS02815	COG1466	dna polymerase III delta subunit
SCRE_RS02820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SCRE_RS02830	COG2274	protein secretion by the type I secretion system
SCRE_RS02845	COG3290	protein histidine kinase activity
SCRE_RS02910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SCRE_RS02915	COG0549	Belongs to the carbamate kinase family
SCRE_RS02920	COG1288	antiporter activity
SCRE_RS02925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCRE_RS02930	COG1438	arginine binding
SCRE_RS02935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SCRE_RS02940	COG0363	glucosamine-6-phosphate deaminase activity
SCRE_RS02955	COG2723	6-phospho-beta-galactosidase activity
SCRE_RS02965	COG4095	Psort location CytoplasmicMembrane, score
SCRE_RS02975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SCRE_RS02975	COG3711	transcriptional antiterminator
SCRE_RS02980	COG1447	Phosphotransferase system cellobiose-specific component IIA
SCRE_RS02990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCRE_RS03005	COG4122	O-methyltransferase activity
SCRE_RS03010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SCRE_RS03025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SCRE_RS03030	COG1132	(ABC) transporter
SCRE_RS03040	COG1396	sequence-specific DNA binding
SCRE_RS03050	COG2348	transferase activity, transferring amino-acyl groups
SCRE_RS03060	COG1078	dGTPase activity
SCRE_RS03085	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SCRE_RS03090	COG2884	Cell division ATP-binding protein ftsE
SCRE_RS03095	COG2177	Part of the ABC transporter FtsEX involved in
SCRE_RS03105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SCRE_RS03105	COG1199	ATP-dependent helicase activity
SCRE_RS03115	COG0772	Belongs to the SEDS family
SCRE_RS03120	COG0693	protein deglycase activity
SCRE_RS03130	COG0187	DNA topoisomerase II activity
SCRE_RS03135	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SCRE_RS03140	COG2706	6-phosphogluconolactonase activity
SCRE_RS03145	COG0745	RESPONSE REGULATOR receiver
SCRE_RS03150	COG3850	Histidine kinase
SCRE_RS03150	COG5002	protein histidine kinase activity
SCRE_RS03155	COG0628	permease
SCRE_RS03165	COG0028	Belongs to the TPP enzyme family
SCRE_RS03170	COG3527	Alpha-acetolactate decarboxylase
SCRE_RS03175	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SCRE_RS03190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SCRE_RS03200	COG4443	Transcriptional Coactivator p15 (PC4)
SCRE_RS03205	COG4152	abc transporter atp-binding protein
SCRE_RS03210	COG1668	transmembrane transport
SCRE_RS03215	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SCRE_RS03220	COG1074	ATP-dependent DNA helicase activity
SCRE_RS03225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SCRE_RS03230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SCRE_RS03235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SCRE_RS03240	COG0297	glycogen (starch) synthase activity
SCRE_RS03245	COG0058	SHG alpha-glucan phosphorylase activity
SCRE_RS03260	COG0356	it plays a direct role in the translocation of protons across the membrane
SCRE_RS03265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SCRE_RS03270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SCRE_RS03275	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SCRE_RS03280	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SCRE_RS03295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SCRE_RS03315	COG1132	(ABC) transporter
SCRE_RS03330	COG1380	Effector of murein hydrolase LrgA
SCRE_RS03335	COG1346	cytolysis
SCRE_RS03340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SCRE_RS03350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SCRE_RS03355	COG0492	ferredoxin-NADP+ reductase activity
SCRE_RS03365	COG1349	DNA-binding transcription factor activity
SCRE_RS03370	COG1105	Belongs to the carbohydrate kinase PfkB family
SCRE_RS03375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SCRE_RS03375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SCRE_RS03375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SCRE_RS03385	COG1307	EDD domain protein, DegV family
SCRE_RS03390	COG0617	tRNA 3'-terminal CCA addition
SCRE_RS03395	COG0488	(ABC) transporter
SCRE_RS03410	COG0072	phenylalanine-tRNA ligase activity
SCRE_RS03410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCRE_RS03425	COG1268	BioY protein
SCRE_RS03435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SCRE_RS03440	COG0577	efflux transmembrane transporter activity
SCRE_RS03445	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SCRE_RS03450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SCRE_RS03470	COG0300	oxidoreductase activity
SCRE_RS03485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SCRE_RS03485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SCRE_RS03495	COG1131	(ABC) transporter
SCRE_RS03500	COG1725	Transcriptional regulator
SCRE_RS03510	COG0205	6-phosphofructokinase activity
SCRE_RS03515	COG0469	pyruvate kinase activity
SCRE_RS03525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SCRE_RS03530	COG0210	DNA helicase
SCRE_RS03550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SCRE_RS03555	COG0196	riboflavin kinase activity
SCRE_RS03560	COG1393	Belongs to the ArsC family
SCRE_RS03565	COG4476	Belongs to the UPF0223 family
SCRE_RS03570	COG0483	inositol monophosphate 1-phosphatase activity
SCRE_RS03575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SCRE_RS03575	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SCRE_RS03585	COG0573	inorganic phosphate transmembrane transporter activity
SCRE_RS03590	COG0581	inorganic phosphate transmembrane transporter activity
SCRE_RS03595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SCRE_RS03600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SCRE_RS03605	COG0704	Plays a role in the regulation of phosphate uptake
SCRE_RS03610	COG2003	Belongs to the UPF0758 family
SCRE_RS03615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SCRE_RS03630	COG1104	cysteine desulfurase activity
SCRE_RS03635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SCRE_RS03645	COG2357	RelA SpoT domain protein
SCRE_RS03650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SCRE_RS03655	COG0564	pseudouridine synthase activity
SCRE_RS03660	COG0280	phosphate acetyltransferase
SCRE_RS03665	COG1194	a g-specific adenine glycosylase
SCRE_RS03675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SCRE_RS03680	COG4684	Psort location CytoplasmicMembrane, score
SCRE_RS03685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SCRE_RS03695	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SCRE_RS03715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SCRE_RS03730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SCRE_RS03735	COG0222	ribosome binding
SCRE_RS03740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SCRE_RS03745	COG0336	Belongs to the RNA methyltransferase TrmD family
SCRE_RS03750	COG0803	Belongs to the bacterial solute-binding protein 9 family
SCRE_RS03750	COG3443	Belongs to the bacterial solute-binding protein 9 family
SCRE_RS03765	COG1956	GAF domain-containing protein
SCRE_RS03770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SCRE_RS03780	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SCRE_RS03780	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SCRE_RS03785	COG1609	Transcriptional regulator
SCRE_RS03790	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SCRE_RS03800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SCRE_RS03810	COG0726	polysaccharide deacetylase
SCRE_RS03820	COG0083	homoserine kinase activity
SCRE_RS03840	COG2814	Major facilitator Superfamily
SCRE_RS03855	COG0167	dihydroorotate dehydrogenase activity
SCRE_RS03860	COG0284	orotidine-5'-phosphate decarboxylase activity
SCRE_RS03870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SCRE_RS03875	COG4479	Belongs to the UPF0346 family
SCRE_RS03880	COG1702	phosphate starvation-inducible protein PhoH
SCRE_RS03900	COG0686	Belongs to the AlaDH PNT family
SCRE_RS03920	COG1132	(ABC) transporter
SCRE_RS03925	COG1132	(ABC) transporter
SCRE_RS03930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SCRE_RS03935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SCRE_RS03970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SCRE_RS03975	COG0237	dephospho-CoA kinase activity
SCRE_RS03980	COG2814	Major facilitator Superfamily
SCRE_RS03990	COG0557	exoribonuclease II activity
SCRE_RS03995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SCRE_RS04005	COG0658	competence protein
SCRE_RS04005	COG2333	competence protein COMEC
SCRE_RS04020	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SCRE_RS04025	COG1051	belongs to the nudix hydrolase family
SCRE_RS04030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SCRE_RS04035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SCRE_RS04040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SCRE_RS04050	COG4109	DRTGG domain
SCRE_RS04055	COG0024	Methionine aminopeptidase
SCRE_RS04065	COG1846	Transcriptional regulator
SCRE_RS04075	COG2246	polysaccharide biosynthetic process
SCRE_RS04080	COG4708	membrane
SCRE_RS04090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SCRE_RS04095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SCRE_RS04100	COG1597	lipid kinase activity
SCRE_RS04105	COG1523	belongs to the glycosyl hydrolase 13 family
SCRE_RS04110	COG0228	four-way junction DNA binding
SCRE_RS04115	COG1837	Belongs to the UPF0109 family
SCRE_RS04120	COG1827	regulation of RNA biosynthetic process
SCRE_RS04135	COG3142	Participates in the control of copper homeostasis
SCRE_RS04140	COG2315	Protein conserved in bacteria
SCRE_RS04150	COG1132	(ABC) transporter
SCRE_RS04155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SCRE_RS04170	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SCRE_RS04175	COG1970	mechanosensitive ion channel activity
SCRE_RS04180	COG0358	DNA primase activity
SCRE_RS04185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SCRE_RS04190	COG2151	metal-sulfur cluster biosynthetic enzyme
SCRE_RS04200	COG0785	Cytochrome C biogenesis protein
SCRE_RS04205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCRE_RS04210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCRE_RS04210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCRE_RS04215	COG4753	response regulator
SCRE_RS04215	COG2207	Transcriptional regulator
SCRE_RS04220	COG2972	Histidine kinase
SCRE_RS04235	COG4555	ABC transporter
SCRE_RS04250	COG0038	chloride channel
SCRE_RS04260	COG0534	Mate efflux family protein
SCRE_RS04265	COG1942	4-Oxalocrotonate Tautomerase
SCRE_RS04270	COG1435	thymidine kinase activity
SCRE_RS04275	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SCRE_RS04280	COG2890	protein-(glutamine-N5) methyltransferase activity
SCRE_RS04285	COG0009	L-threonylcarbamoyladenylate synthase
SCRE_RS04290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SCRE_RS04300	COG0741	lytic transglycosylase activity
SCRE_RS04365	COG2188	Transcriptional regulator
SCRE_RS04375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SCRE_RS04380	COG4974	Belongs to the 'phage' integrase family
SCRE_RS04385	COG0095	Lipoate-protein ligase
SCRE_RS04390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SCRE_RS04395	COG0508	dehydrogenase complex catalyzes the overall conversion of
SCRE_RS04400	COG0022	dehydrogenase e1 component
SCRE_RS04405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SCRE_RS04425	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SCRE_RS04430	COG0135	phosphoribosylanthranilate isomerase activity
SCRE_RS04435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SCRE_RS04440	COG0758	DNA mediated transformation
SCRE_RS04445	COG0110	maltose O-acetyltransferase activity
SCRE_RS04450	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SCRE_RS04455	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SCRE_RS04460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SCRE_RS04475	COG0583	DNA-binding transcription factor activity
SCRE_RS04480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SCRE_RS04485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SCRE_RS04490	COG1024	Enoyl-CoA hydratase
SCRE_RS04495	COG0183	Belongs to the thiolase family
SCRE_RS04500	COG1250	3-hydroxyacyl-CoA dehydrogenase
SCRE_RS04505	COG1960	acyl-CoA dehydrogenase activity
SCRE_RS04510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SCRE_RS04515	COG3764	Sortase (surface protein transpeptidase)
SCRE_RS04520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SCRE_RS04525	COG0039	L-malate dehydrogenase activity
SCRE_RS04540	COG0539	negative regulation of cytoplasmic translation
SCRE_RS04565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SCRE_RS04575	COG2184	nucleotidyltransferase activity
SCRE_RS04590	COG0187	DNA topoisomerase II activity
SCRE_RS04595	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SCRE_RS04605	COG2131	deaminase
SCRE_RS04610	COG1309	transcriptional regulator
SCRE_RS04655	COG2814	Major facilitator Superfamily
SCRE_RS04660	COG0017	Asparaginyl-tRNA synthetase
SCRE_RS04670	COG0436	Aminotransferase
SCRE_RS04680	COG1846	Transcriptional regulator
SCRE_RS04690	COG3022	response to hydroperoxide
SCRE_RS04700	COG1272	protein, Hemolysin III
SCRE_RS04705	COG1079	Belongs to the binding-protein-dependent transport system permease family
SCRE_RS04710	COG4603	Belongs to the binding-protein-dependent transport system permease family
SCRE_RS04715	COG3845	ABC transporter
SCRE_RS04720	COG1744	ABC transporter substrate-binding protein PnrA-like
SCRE_RS04725	COG0295	cytidine deaminase activity
SCRE_RS04730	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SCRE_RS04740	COG2813	Specifically methylates the guanine in position
SCRE_RS04745	COG1072	(Pantothenic acid kinase))
SCRE_RS04770	COG5002	protein histidine kinase activity
SCRE_RS04775	COG0745	RESPONSE REGULATOR receiver
SCRE_RS04830	COG1674	ftsk spoiiie
SCRE_RS04865	COG1940	carbohydrate kinase activity
SCRE_RS04870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SCRE_RS04875	COG0505	Belongs to the CarA family
SCRE_RS04880	COG0540	Belongs to the ATCase OTCase family
SCRE_RS04890	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SCRE_RS04900	COG1481	regulation of sporulation
SCRE_RS04905	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SCRE_RS04910	COG1660	Displays ATPase and GTPase activities
SCRE_RS04930	COG0647	UMP catabolic process
SCRE_RS04945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SCRE_RS04955	COG0456	acetyltransferase
SCRE_RS04960	COG0556	nucleotide-excision repair
SCRE_RS04975	COG0488	(ABC) transporter
SCRE_RS04980	COG1132	(ABC) transporter
SCRE_RS04995	COG1705	Flagellar rod assembly protein muramidase FlgJ
SCRE_RS04995	COG1388	LysM domain
SCRE_RS05000	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SCRE_RS05005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SCRE_RS05015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SCRE_RS05025	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SCRE_RS05030	COG0038	chloride channel
SCRE_RS05055	COG2824	Alkylphosphonate utilization operon protein PhnA
SCRE_RS05060	COG0564	pseudouridine synthase activity
SCRE_RS05070	COG0583	DNA-binding transcription factor activity
SCRE_RS05080	COG1937	Protein conserved in bacteria
SCRE_RS05090	COG1054	Belongs to the UPF0176 family
SCRE_RS05095	COG0446	pyridine nucleotide-disulphide oxidoreductase
SCRE_RS05100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SCRE_RS05100	COG0425	Belongs to the sulfur carrier protein TusA family
SCRE_RS05115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SCRE_RS05130	COG0301	tRNA thio-modification
SCRE_RS05135	COG1104	cysteine desulfurase activity
SCRE_RS05140	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SCRE_RS05145	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SCRE_RS05150	COG0517	IMP dehydrogenase activity
SCRE_RS05155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SCRE_RS05155	COG0574	Belongs to the PEP-utilizing enzyme family
SCRE_RS05170	COG1177	transmembrane transport
SCRE_RS05175	COG1176	ABC-type spermidine putrescine transport system, permease component I
SCRE_RS05180	COG3842	ATPase activity
SCRE_RS05185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SCRE_RS05195	COG0481	GTPase activity
SCRE_RS05200	COG0561	phosphatase activity
SCRE_RS05205	COG2195	Cleaves the N-terminal amino acid of tripeptides
SCRE_RS05215	COG0572	uridine kinase
SCRE_RS05220	COG0673	inositol 2-dehydrogenase activity
SCRE_RS05225	COG0513	Belongs to the DEAD box helicase family
SCRE_RS05230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SCRE_RS05235	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SCRE_RS05245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SCRE_RS05275	COG0560	Phosphoserine phosphatase
SCRE_RS05280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SCRE_RS05290	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SCRE_RS05295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SCRE_RS05300	COG3442	glutamine amidotransferase
SCRE_RS05310	COG0488	(ABC) transporter
SCRE_RS05335	COG0826	peptidase U32
SCRE_RS05360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SCRE_RS05365	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SCRE_RS05380	COG3091	SprT-like family
SCRE_RS05385	COG2183	response to ionizing radiation
SCRE_RS05390	COG0701	Predicted permease
SCRE_RS05395	COG3689	TIGRFAM TIGR03943 family protein
SCRE_RS05400	COG0477	Major facilitator Superfamily
SCRE_RS05405	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SCRE_RS05410	COG0552	protein localization to endoplasmic reticulum
SCRE_RS05415	COG0561	phosphatase activity
SCRE_RS05420	COG0561	phosphatase activity
SCRE_RS05445	COG1388	LysM domain
SCRE_RS05445	COG0860	N-Acetylmuramoyl-L-alanine amidase
SCRE_RS05515	COG0740	serine-type endopeptidase activity
SCRE_RS05520	COG4695	Portal protein
SCRE_RS05545	COG0270	DNA (cytosine-5-)-methyltransferase activity
SCRE_RS05610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SCRE_RS05610	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SCRE_RS05665	COG1196	nuclear chromosome segregation
SCRE_RS05670	COG0571	ribonuclease III activity
SCRE_RS05675	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SCRE_RS05680	COG5002	protein histidine kinase activity
SCRE_RS05685	COG0745	RESPONSE REGULATOR receiver
SCRE_RS05695	COG0438	transferase activity, transferring glycosyl groups
SCRE_RS05705	COG1609	Transcriptional regulator
SCRE_RS05710	COG0006	proline dipeptidase activity
SCRE_RS05715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SCRE_RS05720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SCRE_RS05725	COG1088	dTDP-glucose 4,6-dehydratase activity
SCRE_RS05735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SCRE_RS05740	COG0494	nUDIX hydrolase
SCRE_RS05745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCRE_RS05750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SCRE_RS05755	COG2384	SAM-dependent methyltransferase
SCRE_RS05770	COG3754	Rhamnan synthesis protein F
SCRE_RS05800	COG1091	dTDP-4-dehydrorhamnose reductase activity
SCRE_RS05805	COG0463	Glycosyl transferase, family 2
SCRE_RS05880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SCRE_RS05990	COG0740	serine-type endopeptidase activity
SCRE_RS06000	COG0789	Transcriptional regulator
SCRE_RS06005	COG1802	Transcriptional regulator
SCRE_RS06005	COG4626	Terminase
SCRE_RS06030	COG0270	DNA (cytosine-5-)-methyltransferase activity
SCRE_RS06210	COG1404	Belongs to the peptidase S8 family
SCRE_RS06215	COG0464	growth
SCRE_RS06240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SCRE_RS06240	COG0551	DNA topoisomerase type I activity
SCRE_RS06265	COG3344	reverse transcriptase
SCRE_RS06300	COG1484	DNA-dependent DNA replication
SCRE_RS06325	COG1191	sigma factor activity
SCRE_RS06330	COG2226	methyltransferase
SCRE_RS06400	COG1132	(ABC) transporter
SCRE_RS06405	COG1132	(ABC) transporter
SCRE_RS06405	COG2375	cellular response to nickel ion
SCRE_RS06410	COG1129	ABC transporter
SCRE_RS06480	COG1484	DNA-dependent DNA replication
SCRE_RS06495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SCRE_RS06505	COG0077	Prephenate dehydratase
SCRE_RS06515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SCRE_RS06520	COG3679	Belongs to the UPF0342 family
SCRE_RS06525	COG0287	Prephenate dehydrogenase
SCRE_RS06535	COG0730	response to heat
SCRE_RS06540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SCRE_RS06545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SCRE_RS06550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SCRE_RS06555	COG0710	3-dehydroquinate dehydratase activity
SCRE_RS06560	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SCRE_RS06565	COG1368	sulfuric ester hydrolase activity
SCRE_RS06575	COG0813	purine-nucleoside phosphorylase activity
SCRE_RS06585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SCRE_RS06590	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SCRE_RS06615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SCRE_RS06625	COG1191	sigma factor activity
SCRE_RS06630	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SCRE_RS06635	COG0772	Belongs to the SEDS family
SCRE_RS06655	COG0406	alpha-ribazole phosphatase activity
SCRE_RS06660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SCRE_RS06690	COG1882	Formate acetyltransferase
SCRE_RS06695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCRE_RS06705	COG1447	Phosphotransferase system cellobiose-specific component IIA
SCRE_RS06715	COG1349	DNA-binding transcription factor activity
SCRE_RS06720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SCRE_RS06725	COG1959	2 iron, 2 sulfur cluster binding
SCRE_RS06745	COG1309	transcriptional regulator
SCRE_RS06765	COG0716	FMN binding
SCRE_RS06770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SCRE_RS06775	COG0254	rRNA binding
SCRE_RS06790	COG1063	alcohol dehydrogenase
SCRE_RS06795	COG1125	glycine betaine transport
SCRE_RS06800	COG1732	Glycine betaine
SCRE_RS06810	COG1573	uracil-dna glycosylase
SCRE_RS06820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCRE_RS06835	COG0322	excinuclease ABC activity
SCRE_RS06840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SCRE_RS06850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SCRE_RS06865	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SCRE_RS06880	COG1476	TRANSCRIPTIONal
SCRE_RS06895	COG0204	Acyl-transferase
SCRE_RS06900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SCRE_RS06905	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SCRE_RS06910	COG2827	Endonuclease containing a URI domain
SCRE_RS06920	COG1755	Isoprenylcysteine carboxyl methyltransferase
SCRE_RS06925	COG2723	6-phospho-beta-galactosidase activity
SCRE_RS06930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCRE_RS06930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCRE_RS06935	COG1447	Phosphotransferase system cellobiose-specific component IIA
SCRE_RS06940	COG3711	transcriptional antiterminator
SCRE_RS06945	COG3064	Membrane
SCRE_RS06945	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SCRE_RS06945	COG3583	domain protein
SCRE_RS06950	COG1105	Belongs to the carbohydrate kinase PfkB family
SCRE_RS06955	COG3775	system Galactitol-specific IIC component
SCRE_RS06975	COG0698	ribose 5-phosphate isomerase
SCRE_RS06995	COG2801	Transposase and inactivated derivatives
SCRE_RS07000	COG0513	Belongs to the DEAD box helicase family
SCRE_RS07020	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SCRE_RS07050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SCRE_RS07060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SCRE_RS07065	COG0768	penicillin binding
SCRE_RS07075	COG3620	sequence-specific DNA binding
SCRE_RS07080	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
SCRE_RS07155	COG0588	phosphoglycerate mutase activity
SCRE_RS07170	COG1307	EDD domain protein, DegV family
SCRE_RS07175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SCRE_RS07180	COG4605	iron ion homeostasis
SCRE_RS07185	COG4604	ABC transporter, ATP-binding protein
SCRE_RS07195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SCRE_RS07200	COG0497	DNA recombination
SCRE_RS07205	COG1438	arginine binding
SCRE_RS07210	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SCRE_RS07220	COG1722	exodeoxyribonuclease VII activity
SCRE_RS07225	COG1570	exodeoxyribonuclease VII activity
SCRE_RS07230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SCRE_RS07235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SCRE_RS07240	COG0577	efflux transmembrane transporter activity
SCRE_RS07245	COG1136	(ABC) transporter
SCRE_RS07270	COG4703	Protein of unknown function (DUF1797)
SCRE_RS07275	COG0542	response to heat
SCRE_RS07290	COG2378	regulation of single-species biofilm formation
SCRE_RS07310	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SCRE_RS07315	COG1242	4 iron, 4 sulfur cluster binding
SCRE_RS07325	COG0671	phosphoesterase, PA-phosphatase related
SCRE_RS07330	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SCRE_RS07355	COG1187	pseudouridine synthase activity
SCRE_RS07365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SCRE_RS07370	COG4974	Belongs to the 'phage' integrase family
SCRE_RS07375	COG0517	IMP dehydrogenase activity
SCRE_RS07385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SCRE_RS07390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SCRE_RS07410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SCRE_RS07415	COG1254	Belongs to the acylphosphatase family
SCRE_RS07435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SCRE_RS07450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SCRE_RS07460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SCRE_RS07465	COG1160	GTP binding
SCRE_RS07470	COG1484	DNA-dependent DNA replication
SCRE_RS07480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SCRE_RS07490	COG2190	(PTS) system
SCRE_RS07490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCRE_RS07490	COG1263	PTS System
SCRE_RS07495	COG0745	RESPONSE REGULATOR receiver
SCRE_RS07500	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SCRE_RS07515	COG0501	Belongs to the peptidase M48B family
SCRE_RS07520	COG1704	LemA family
SCRE_RS07525	COG0357	Ribosomal RNA small subunit methyltransferase G
SCRE_RS07530	COG1442	glycosyl transferase family 8
SCRE_RS07535	COG4221	oxidoreductase activity
SCRE_RS07545	COG1122	ATPase activity
SCRE_RS07575	COG4720	Psort location CytoplasmicMembrane, score
SCRE_RS07670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SCRE_RS07675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCRE_RS07680	COG1464	Belongs to the NlpA lipoprotein family
SCRE_RS07685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SCRE_RS07695	COG1396	sequence-specific DNA binding
SCRE_RS07700	COG0217	transcriptional regulatory protein
SCRE_RS07705	COG1323	Belongs to the UPF0348 family
SCRE_RS07715	COG2226	methyltransferase
SCRE_RS07720	COG0799	negative regulation of ribosome biogenesis
SCRE_RS07725	COG1713	HD superfamily hydrolase involved in NAD metabolism
SCRE_RS07730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SCRE_RS07735	COG1534	Rna-binding protein
SCRE_RS07740	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SCRE_RS07745	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SCRE_RS07760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SCRE_RS07770	COG0154	amidase activity
SCRE_RS07775	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SCRE_RS07780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SCRE_RS07785	COG1335	isochorismatase
SCRE_RS07790	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SCRE_RS07795	COG0436	Aminotransferase
SCRE_RS07800	COG0589	response to stress
SCRE_RS07805	COG0561	phosphatase activity
SCRE_RS07810	COG0252	asparaginase activity
SCRE_RS07815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SCRE_RS07820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SCRE_RS07825	COG0736	holo-[acyl-carrier-protein] synthase activity
SCRE_RS07830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SCRE_RS07845	COG1482	cell wall glycoprotein biosynthetic process
SCRE_RS07850	COG2188	Transcriptional regulator
SCRE_RS07855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCRE_RS07860	COG2723	6-phospho-beta-galactosidase activity
SCRE_RS07865	COG1447	Phosphotransferase system cellobiose-specific component IIA
SCRE_RS07870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCRE_RS07875	COG1132	(ABC) transporter
SCRE_RS07890	COG1902	pentaerythritol trinitrate reductase activity
SCRE_RS07895	COG0242	peptide deformylase activity
SCRE_RS07900	COG1940	carbohydrate kinase activity
SCRE_RS07905	COG1263	PTS System
SCRE_RS07905	COG2190	(PTS) system
SCRE_RS07905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCRE_RS07910	COG1621	beta-fructofuranosidase activity
SCRE_RS07915	COG1609	Transcriptional regulator
SCRE_RS07925	COG4608	Belongs to the ABC transporter superfamily
SCRE_RS07930	COG0444	Belongs to the ABC transporter superfamily
SCRE_RS07935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SCRE_RS07940	COG0601	transmembrane transport
SCRE_RS07945	COG4166	transmembrane transport
SCRE_RS07950	COG4166	transmembrane transport
SCRE_RS07960	COG0504	CTP synthase activity
SCRE_RS07965	COG3343	RNA polymerase activity
SCRE_RS07975	COG0544	peptidyl-prolyl cis-trans isomerase activity
SCRE_RS07980	COG4475	Protein of unknown function (DUF436)
SCRE_RS07985	COG4720	Psort location CytoplasmicMembrane, score
SCRE_RS07990	COG0351	phosphomethylpyrimidine kinase
SCRE_RS07995	COG0101	tRNA pseudouridine synthase activity
SCRE_RS08005	COG0484	heat shock protein binding
SCRE_RS08010	COG0443	Heat shock 70 kDa protein
SCRE_RS08015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SCRE_RS08020	COG1420	regulation of RNA biosynthetic process
SCRE_RS08025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SCRE_RS08030	COG3037	sugar-specific permease SgaT UlaA
SCRE_RS08040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SCRE_RS08050	COG0588	phosphoglycerate mutase activity
SCRE_RS08055	COG2848	UPF0210 protein
SCRE_RS08060	COG3830	Belongs to the UPF0237 family
SCRE_RS08065	COG1609	Transcriptional regulator
SCRE_RS08080	COG3716	PTS system mannose fructose sorbose family IID component
SCRE_RS08085	COG3715	PTS system
SCRE_RS08090	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCRE_RS08095	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SCRE_RS08105	COG1028	Short-chain dehydrogenase reductase Sdr
SCRE_RS08130	COG5492	domain, Protein
SCRE_RS08135	COG0386	Belongs to the glutathione peroxidase family
SCRE_RS08145	COG0281	malic enzyme
SCRE_RS08155	COG0583	DNA-binding transcription factor activity
SCRE_RS08160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SCRE_RS08165	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SCRE_RS08180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SCRE_RS08185	COG3842	ATPase activity
SCRE_RS08195	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SCRE_RS08200	COG0215	cysteine-tRNA ligase activity
SCRE_RS08205	COG1045	serine acetyltransferase
SCRE_RS08210	COG1185	polyribonucleotide nucleotidyltransferase activity
SCRE_RS08215	COG1164	Oligoendopeptidase f
SCRE_RS08230	COG1187	pseudouridine synthase activity
SCRE_RS08245	COG0242	peptide deformylase activity
SCRE_RS08255	COG2176	DNA-directed DNA polymerase activity
SCRE_RS08260	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SCRE_RS08265	COG1523	belongs to the glycosyl hydrolase 13 family
SCRE_RS08285	COG3590	peptidase
SCRE_RS08310	COG1490	D-aminoacyl-tRNA deacylase activity
SCRE_RS08320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SCRE_RS08325	COG2264	protein methyltransferase activity
SCRE_RS08345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SCRE_RS08365	COG1428	Deoxynucleoside kinase
SCRE_RS08380	COG0459	protein refolding
SCRE_RS08385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SCRE_RS08395	COG3716	PTS system mannose fructose sorbose family IID component
SCRE_RS08400	COG3715	PTS system
SCRE_RS08420	COG2197	response regulator
SCRE_RS08425	COG4585	Histidine kinase
SCRE_RS08440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCRE_RS08445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCRE_RS08455	COG1363	Peptidase, m42
SCRE_RS08465	COG0285	dihydrofolate synthase activity
SCRE_RS08475	COG0442	prolyl-tRNA aminoacylation
SCRE_RS08480	COG0750	zinc metalloprotease
SCRE_RS08485	COG4589	Belongs to the CDS family
SCRE_RS08490	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SCRE_RS08505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SCRE_RS08525	COG3623	hexulose-6-phosphate isomerase
SCRE_RS08535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SCRE_RS08545	COG3037	sugar-specific permease SgaT UlaA
SCRE_RS08560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SCRE_RS08590	COG4537	Required for transformation and DNA binding
SCRE_RS08595	COG1459	type II secretion system
SCRE_RS08600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SCRE_RS08610	COG0174	glutamine synthetase
SCRE_RS08615	COG0789	Transcriptional regulator
SCRE_RS08635	COG0126	phosphoglycerate kinase activity
SCRE_RS08645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SCRE_RS08650	COG0085	RNA polymerase activity
SCRE_RS08655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCRE_RS08665	COG2226	methyltransferase
SCRE_RS08675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SCRE_RS08680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SCRE_RS08690	COG0756	dUTP diphosphatase activity
SCRE_RS08700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SCRE_RS08705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SCRE_RS08730	COG1674	ftsk spoiiie
SCRE_RS08760	COG0582	viral genome integration into host DNA
SCRE_RS08850	COG0203	ribosomal protein L17
SCRE_RS08855	COG0202	RNA polymerase activity
SCRE_RS08860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SCRE_RS08865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SCRE_RS08870	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SCRE_RS08875	COG0563	adenylate kinase activity
SCRE_RS08880	COG0201	protein transport
SCRE_RS08885	COG0200	Binds to the 23S rRNA
SCRE_RS08890	COG1841	ribosomal large subunit assembly
SCRE_RS08895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SCRE_RS08905	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SCRE_RS08910	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SCRE_RS08915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SCRE_RS08920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SCRE_RS08925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SCRE_RS08930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SCRE_RS08940	COG0255	Belongs to the universal ribosomal protein uL29 family
SCRE_RS08950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SCRE_RS08955	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SCRE_RS08965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SCRE_RS08970	COG0089	rRNA binding
SCRE_RS08975	COG0088	Forms part of the polypeptide exit tunnel
SCRE_RS08980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SCRE_RS08985	COG0051	transcription antitermination factor activity, RNA binding
SCRE_RS09000	COG0343	queuine tRNA-ribosyltransferase activity
SCRE_RS09015	COG1832	CoA-binding protein
SCRE_RS09020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SCRE_RS09020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SCRE_RS09040	COG5002	protein histidine kinase activity
SCRE_RS09120	COG0602	queuosine metabolic process
SCRE_RS09140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SCRE_RS09160	COG0285	dihydrofolate synthase activity
SCRE_RS09165	COG3906	Belongs to the UPF0473 family
SCRE_RS09170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SCRE_RS09175	COG4472	Bacterial protein of unknown function (DUF965)
SCRE_RS09190	COG1393	Belongs to the ArsC family
SCRE_RS09195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SCRE_RS09200	COG1058	Belongs to the CinA family
SCRE_RS09200	COG1546	Belongs to the CinA family
SCRE_RS09205	COG1136	(ABC) transporter
SCRE_RS09205	COG0577	efflux transmembrane transporter activity
SCRE_RS09230	COG0519	Catalyzes the synthesis of GMP from XMP
SCRE_RS09235	COG0632	four-way junction helicase activity
SCRE_RS09240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SCRE_RS09255	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SCRE_RS09260	COG1438	arginine binding
SCRE_RS09265	COG0018	arginyl-trna synthetase
SCRE_RS09270	COG1780	Probably involved in ribonucleotide reductase function
SCRE_RS09280	COG0058	SHG alpha-glucan phosphorylase activity
SCRE_RS09285	COG1640	4-alpha-glucanotransferase
SCRE_RS09290	COG2182	Extracellular solute-binding protein
SCRE_RS09295	COG1175	transmembrane transport
SCRE_RS09300	COG3833	ABC-type maltose transport systems, permease component
SCRE_RS09305	COG5521	maltodextrose utilization protein MalA
SCRE_RS09310	COG1609	Transcriptional regulator
SCRE_RS09315	COG1523	belongs to the glycosyl hydrolase 13 family
SCRE_RS09320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SCRE_RS09335	COG0124	histidyl-tRNA synthetase
SCRE_RS09340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SCRE_RS09345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SCRE_RS09395	COG4974	Belongs to the 'phage' integrase family
SCRE_RS09415	COG2807	transmembrane transport
SCRE_RS09425	COG2094	Belongs to the DNA glycosylase MPG family
SCRE_RS09435	COG0561	phosphatase activity
SCRE_RS09440	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SCRE_RS09445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCRE_RS09450	COG1696	Membrane protein involved in D-alanine export
SCRE_RS09530	COG0561	phosphatase activity
SCRE_RS09550	COG1011	Hydrolase
SCRE_RS09560	COG0305	Participates in initiation and elongation during chromosome replication
SCRE_RS09575	COG0445	tRNA wobble uridine modification
SCRE_RS09580	COG0482	sulfurtransferase activity
SCRE_RS09590	COG1760	l-serine dehydratase
SCRE_RS09595	COG1760	l-serine dehydratase
SCRE_RS09610	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SCRE_RS09615	COG1122	ATPase activity
SCRE_RS09620	COG1122	ATPase activity
SCRE_RS09625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SCRE_RS09635	COG0612	Peptidase, M16
SCRE_RS09640	COG0612	Peptidase, M16
SCRE_RS09650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SCRE_RS09655	COG0516	GMP reductase activity
SCRE_RS09655	COG0517	IMP dehydrogenase activity
SCRE_RS09660	COG0180	Tryptophanyl-tRNA synthetase
SCRE_RS09665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SCRE_RS09670	COG0149	triose-phosphate isomerase activity
SCRE_RS09680	COG0488	(ABC) transporter
SCRE_RS09720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SCRE_RS09725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCRE_RS09730	COG1475	DNA binding
SCRE_RS09780	COG2801	Transposase and inactivated derivatives