locus-tag	class	description
FOB62_RS00035	COG0601	transmembrane transport
FOB62_RS00045	COG1122	ATPase activity
FOB62_RS00065	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB62_RS00090	COG3942	CHAP domain
FOB62_RS00090	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB62_RS00095	COG2205	protein histidine kinase activity
FOB62_RS00100	COG0745	RESPONSE REGULATOR receiver
FOB62_RS00105	COG0577	efflux transmembrane transporter activity
FOB62_RS00110	COG1136	(ABC) transporter
FOB62_RS00150	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOB62_RS00165	COG0346	lactoylglutathione lyase activity
FOB62_RS00170	COG3764	Sortase (surface protein transpeptidase)
FOB62_RS00185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOB62_RS00195	COG1132	(ABC) transporter
FOB62_RS00200	COG1132	(ABC) transporter
FOB62_RS00225	COG0009	L-threonylcarbamoyladenylate synthase
FOB62_RS00230	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB62_RS00255	COG2233	PERMEase
FOB62_RS00275	COG1174	glycine betaine transport
FOB62_RS00290	COG4221	oxidoreductase activity
FOB62_RS00295	COG0280	phosphate acetyltransferase
FOB62_RS00300	COG0564	pseudouridine synthase activity
FOB62_RS00310	COG2357	RelA SpoT domain protein
FOB62_RS00325	COG1104	cysteine desulfurase activity
FOB62_RS00345	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOB62_RS00355	COG0628	permease
FOB62_RS00365	COG1917	Cupin 2, conserved barrel domain protein
FOB62_RS00365	COG4977	sequence-specific DNA binding
FOB62_RS00370	COG0038	chloride channel
FOB62_RS00380	COG3493	citrate carrier protein
FOB62_RS00385	COG3290	protein histidine kinase activity
FOB62_RS00390	COG4565	transcriptional regulatory protein
FOB62_RS00400	COG1177	transmembrane transport
FOB62_RS00405	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB62_RS00435	COG0302	gtp cyclohydrolase
FOB62_RS00440	COG0285	dihydrofolate synthase activity
FOB62_RS00455	COG0726	polysaccharide deacetylase
FOB62_RS00460	COG1686	Belongs to the peptidase S11 family
FOB62_RS00475	COG1396	sequence-specific DNA binding
FOB62_RS00490	COG2723	6-phospho-beta-galactosidase activity
FOB62_RS00495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB62_RS00495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB62_RS00500	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB62_RS00505	COG3711	transcriptional antiterminator
FOB62_RS00510	COG3684	Belongs to the aldolase LacD family
FOB62_RS00515	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB62_RS00520	COG0698	ribose 5-phosphate isomerase
FOB62_RS00530	COG1349	DNA-binding transcription factor activity
FOB62_RS00600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOB62_RS00610	COG3425	synthase
FOB62_RS00665	COG0745	RESPONSE REGULATOR receiver
FOB62_RS00670	COG2357	RelA SpoT domain protein
FOB62_RS00675	COG0737	Belongs to the 5'-nucleotidase family
FOB62_RS00680	COG0242	peptide deformylase activity
FOB62_RS00685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB62_RS00690	COG1132	(ABC) transporter
FOB62_RS00700	COG0488	(ABC) transporter
FOB62_RS00725	COG1388	LysM domain
FOB62_RS00725	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB62_RS00730	COG1388	LysM domain
FOB62_RS00730	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB62_RS00735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB62_RS00735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB62_RS00735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB62_RS00740	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB62_RS00745	COG1349	DNA-binding transcription factor activity
FOB62_RS00795	COG1837	Belongs to the UPF0109 family
FOB62_RS00805	COG0584	glycerophosphoryl diester phosphodiesterase
FOB62_RS00815	COG0577	efflux transmembrane transporter activity
FOB62_RS00820	COG1136	(ABC) transporter
FOB62_RS00825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB62_RS00860	COG0564	pseudouridine synthase activity
FOB62_RS00870	COG0583	DNA-binding transcription factor activity
FOB62_RS00875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOB62_RS00905	COG1104	cysteine desulfurase activity
FOB62_RS00915	COG0285	dihydrofolate synthase activity
FOB62_RS00920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB62_RS00940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOB62_RS00945	COG1368	sulfuric ester hydrolase activity
FOB62_RS00995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB62_RS01010	COG0463	Glycosyl transferase, family 2
FOB62_RS01050	COG1216	Glycosyl transferase, family 2
FOB62_RS01050	COG1442	glycosyl transferase family 8
FOB62_RS01065	COG2151	metal-sulfur cluster biosynthetic enzyme
FOB62_RS01070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB62_RS01075	COG0358	DNA primase activity
FOB62_RS01080	COG1970	mechanosensitive ion channel activity
FOB62_RS01095	COG0436	Aminotransferase
FOB62_RS01110	COG2321	neutral zinc metallopeptidase
FOB62_RS01115	COG1136	(ABC) transporter
FOB62_RS01120	COG0577	efflux transmembrane transporter activity
FOB62_RS01210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB62_RS01215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOB62_RS01220	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOB62_RS01225	COG1523	belongs to the glycosyl hydrolase 13 family
FOB62_RS01230	COG1597	lipid kinase activity
FOB62_RS01240	COG4708	membrane
FOB62_RS01260	COG1131	(ABC) transporter
FOB62_RS01325	COG0772	Belongs to the SEDS family
FOB62_RS01340	COG0038	chloride channel
FOB62_RS01350	COG0716	FMN binding
FOB62_RS01360	COG0625	glutathione transferase activity
FOB62_RS01365	COG2153	protein acetylation
FOB62_RS01370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOB62_RS01390	COG3716	PTS system mannose fructose sorbose family IID component
FOB62_RS01395	COG3715	PTS system
FOB62_RS01420	COG2222	sugar isomerase
FOB62_RS01425	COG2188	Transcriptional regulator
FOB62_RS01460	COG0017	Asparaginyl-tRNA synthetase
FOB62_RS01465	COG0436	Aminotransferase
FOB62_RS01470	COG1199	ATP-dependent helicase activity
FOB62_RS01470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB62_RS01480	COG2177	Part of the ABC transporter FtsEX involved in
FOB62_RS01485	COG2884	Cell division ATP-binding protein ftsE
FOB62_RS01495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB62_RS01500	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FOB62_RS01505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB62_RS01520	COG0542	response to heat
FOB62_RS01525	COG0542	response to heat
FOB62_RS01530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB62_RS01535	COG1396	sequence-specific DNA binding
FOB62_RS01555	COG5492	domain, Protein
FOB62_RS01575	COG1028	Short-chain dehydrogenase reductase Sdr
FOB62_RS01590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB62_RS01595	COG3715	PTS system
FOB62_RS01600	COG3716	PTS system mannose fructose sorbose family IID component
FOB62_RS01610	COG1609	Transcriptional regulator
FOB62_RS01630	COG1078	dGTPase activity
FOB62_RS01700	COG1191	sigma factor activity
FOB62_RS01705	COG0772	Belongs to the SEDS family
FOB62_RS01715	COG1164	Oligoendopeptidase f
FOB62_RS01720	COG0386	Belongs to the glutathione peroxidase family
FOB62_RS01750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB62_RS01800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB62_RS01805	COG3620	sequence-specific DNA binding
FOB62_RS01825	COG3620	sequence-specific DNA binding
FOB62_RS01845	COG1674	ftsk spoiiie
FOB62_RS01895	COG0433	COG0433 Predicted ATPase
FOB62_RS01915	COG3942	CHAP domain
FOB62_RS01915	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOB62_RS01925	COG0582	viral genome integration into host DNA
FOB62_RS01930	COG0004	ammonium transporteR
FOB62_RS01940	COG4443	Transcriptional Coactivator p15 (PC4)
FOB62_RS01945	COG0826	peptidase U32
FOB62_RS01990	COG2183	response to ionizing radiation
FOB62_RS02000	COG0704	Plays a role in the regulation of phosphate uptake
FOB62_RS02005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB62_RS02015	COG0573	inorganic phosphate transmembrane transporter activity
FOB62_RS02020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOB62_RS02025	COG5002	protein histidine kinase activity
FOB62_RS02030	COG0745	RESPONSE REGULATOR receiver
FOB62_RS02050	COG0701	Predicted permease
FOB62_RS02055	COG3689	TIGRFAM TIGR03943 family protein
FOB62_RS02065	COG1263	PTS System
FOB62_RS02065	COG2190	(PTS) system
FOB62_RS02065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB62_RS02070	COG3711	transcriptional antiterminator
FOB62_RS02075	COG0477	Major facilitator Superfamily
FOB62_RS02080	COG0552	protein localization to endoplasmic reticulum
FOB62_RS02085	COG0561	phosphatase activity
FOB62_RS02090	COG0561	phosphatase activity
FOB62_RS02110	COG1196	nuclear chromosome segregation
FOB62_RS02120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOB62_RS02125	COG5002	protein histidine kinase activity
FOB62_RS02130	COG0745	RESPONSE REGULATOR receiver
FOB62_RS02140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB62_RS02145	COG0765	amino acid transport
FOB62_RS02150	COG0765	amino acid transport
FOB62_RS02175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB62_RS02180	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FOB62_RS02185	COG1461	Dihydroxyacetone kinase
FOB62_RS02190	COG2376	Dihydroxyacetone kinase
FOB62_RS02200	COG2376	Dihydroxyacetone kinase
FOB62_RS02215	COG4555	ABC transporter
FOB62_RS02225	COG0438	transferase activity, transferring glycosyl groups
FOB62_RS02240	COG1609	Transcriptional regulator
FOB62_RS02245	COG0006	proline dipeptidase activity
FOB62_RS02250	COG0778	Nitroreductase
FOB62_RS02255	COG0346	lactoylglutathione lyase activity
FOB62_RS02265	COG0463	Glycosyl transferase, family 2
FOB62_RS02275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOB62_RS02280	COG0557	exoribonuclease II activity
FOB62_RS02295	COG2814	Major facilitator Superfamily
FOB62_RS02300	COG0433	COG0433 Predicted ATPase
FOB62_RS02310	COG1131	(ABC) transporter
FOB62_RS02325	COG1396	sequence-specific DNA binding
FOB62_RS02405	COG2274	protein secretion by the type I secretion system
FOB62_RS02425	COG3279	Response regulator of the LytR AlgR family
FOB62_RS02480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB62_RS02490	COG1573	uracil-dna glycosylase
FOB62_RS02495	COG1702	phosphate starvation-inducible protein PhoH
FOB62_RS02560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB62_RS02585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB62_RS02610	COG0673	inositol 2-dehydrogenase activity
FOB62_RS02625	COG1028	Short-chain dehydrogenase reductase Sdr
FOB62_RS02640	COG1114	Component of the transport system for branched-chain amino acids
FOB62_RS02680	COG1304	FMN binding
FOB62_RS02685	COG1620	l-lactate permease
FOB62_RS02695	COG0708	Exodeoxyribonuclease III
FOB62_RS02700	COG0561	phosphatase activity
FOB62_RS02705	COG1609	Transcriptional regulator
FOB62_RS02720	COG1393	Belongs to the ArsC family
FOB62_RS02735	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOB62_RS02760	COG1774	PSP1 C-terminal conserved region
FOB62_RS02765	COG0470	DNA polymerase III
FOB62_RS02775	COG0517	IMP dehydrogenase activity
FOB62_RS02785	COG0411	ABC transporter
FOB62_RS02795	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB62_RS02835	COG2244	polysaccharide biosynthetic process
FOB62_RS02845	COG1120	ATPase activity
FOB62_RS02850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB62_RS02855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB62_RS02860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB62_RS02875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB62_RS02880	COG1253	flavin adenine dinucleotide binding
FOB62_RS02885	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOB62_RS02890	COG1242	4 iron, 4 sulfur cluster binding
FOB62_RS02895	COG0671	phosphoesterase, PA-phosphatase related
FOB62_RS02900	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOB62_RS02915	COG1187	pseudouridine synthase activity
FOB62_RS02935	COG4175	Glycine betaine
FOB62_RS02970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB62_RS02975	COG1254	Belongs to the acylphosphatase family
FOB62_RS02990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB62_RS03010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB62_RS03020	COG1484	DNA-dependent DNA replication
FOB62_RS03030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB62_RS03035	COG5002	protein histidine kinase activity
FOB62_RS03040	COG0745	RESPONSE REGULATOR receiver
FOB62_RS03055	COG1704	LemA family
FOB62_RS03065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB62_RS03070	COG0569	domain protein
FOB62_RS03080	COG1114	Component of the transport system for branched-chain amino acids
FOB62_RS03100	COG1464	Belongs to the NlpA lipoprotein family
FOB62_RS03110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB62_RS03120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOB62_RS03145	COG0789	Transcriptional regulator
FOB62_RS03155	COG2226	methyltransferase
FOB62_RS03160	COG0799	negative regulation of ribosome biogenesis
FOB62_RS03170	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOB62_RS03180	COG1534	Rna-binding protein
FOB62_RS03185	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOB62_RS03190	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOB62_RS03245	COG0444	Belongs to the ABC transporter superfamily
FOB62_RS03250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB62_RS03255	COG0601	transmembrane transport
FOB62_RS03260	COG4166	transmembrane transport
FOB62_RS03265	COG1686	Belongs to the peptidase S11 family
FOB62_RS03275	COG1686	Belongs to the peptidase S11 family
FOB62_RS03290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOB62_RS03295	COG0719	Fe-S assembly protein
FOB62_RS03305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB62_RS03325	COG0765	amino acid transport
FOB62_RS03375	COG1346	cytolysis
FOB62_RS03385	COG3279	Response regulator of the LytR AlgR family
FOB62_RS03400	COG3343	RNA polymerase activity
FOB62_RS03410	COG0366	Alpha amylase catalytic
FOB62_RS03415	COG0366	Alpha amylase catalytic
FOB62_RS03420	COG0668	transmembrane transport
FOB62_RS03430	COG4720	Psort location CytoplasmicMembrane, score
FOB62_RS03435	COG0351	phosphomethylpyrimidine kinase
FOB62_RS03445	COG0527	aspartate kinase activity
FOB62_RS03490	COG0561	phosphatase activity
FOB62_RS03510	COG3414	Phosphotransferase system galactitol-specific IIB component
FOB62_RS03515	COG3775	system Galactitol-specific IIC component
FOB62_RS03545	COG0732	type I restriction modification DNA specificity domain
FOB62_RS03555	COG4974	Belongs to the 'phage' integrase family
FOB62_RS03620	COG3843	relaxase mobilization nuclease domain protein
FOB62_RS03650	COG1131	(ABC) transporter
FOB62_RS03655	COG1309	transcriptional regulator
FOB62_RS03675	COG0551	DNA topoisomerase type I activity
FOB62_RS03675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB62_RS03760	COG1484	DNA-dependent DNA replication
FOB62_RS03825	COG0582	viral genome integration into host DNA
FOB62_RS03835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB62_RS03845	COG1476	TRANSCRIPTIONal
FOB62_RS03865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB62_RS03890	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FOB62_RS03905	COG1045	serine acetyltransferase
FOB62_RS03920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB62_RS03935	COG3711	transcriptional antiterminator
FOB62_RS03945	COG1126	abc transporter atp-binding protein
FOB62_RS03985	COG1846	Transcriptional regulator
FOB62_RS04010	COG4589	Belongs to the CDS family
FOB62_RS04020	COG1862	Preprotein translocase
FOB62_RS04035	COG1523	belongs to the glycosyl hydrolase 13 family
FOB62_RS04045	COG3842	ATPase activity
FOB62_RS04095	COG1363	Peptidase, m42
FOB62_RS04110	COG1263	PTS System
FOB62_RS04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB62_RS04110	COG2190	(PTS) system
FOB62_RS04115	COG1609	Transcriptional regulator
FOB62_RS04120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB62_RS04135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOB62_RS04140	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB62_RS04145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB62_RS04175	COG1674	ftsk spoiiie
FOB62_RS04230	COG1132	(ABC) transporter
FOB62_RS04280	COG0488	(ABC) transporter
FOB62_RS04295	COG3655	Transcriptional regulator
FOB62_RS04320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOB62_RS04340	COG1882	Formate acetyltransferase
FOB62_RS04345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB62_RS04350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB62_RS04355	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB62_RS04360	COG2390	Transcriptional regulator
FOB62_RS04365	COG1349	DNA-binding transcription factor activity
FOB62_RS04370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB62_RS04375	COG1744	ABC transporter substrate-binding protein PnrA-like
FOB62_RS04400	COG0251	oxidation-reduction process
FOB62_RS04465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB62_RS04470	COG1428	Deoxynucleoside kinase
FOB62_RS04480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB62_RS04485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB62_RS04500	COG1363	Peptidase, m42
FOB62_RS04505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOB62_RS04515	COG1266	CAAX protease self-immunity
FOB62_RS04555	COG4537	Required for transformation and DNA binding
FOB62_RS04560	COG1459	type II secretion system
FOB62_RS04565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB62_RS04585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB62_RS04585	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOB62_RS04595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB62_RS04600	COG1121	(ABC) transporter
FOB62_RS04615	COG0142	geranyltranstransferase activity
FOB62_RS04620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOB62_RS04625	COG4988	ABC transporter
FOB62_RS04630	COG1294	oxidase, subunit
FOB62_RS04635	COG1271	oxidase subunit
FOB62_RS04640	COG1252	NADH dehydrogenase
FOB62_RS04650	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOB62_RS04685	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOB62_RS04685	COG0456	acetyltransferase
FOB62_RS04690	COG1396	sequence-specific DNA binding
FOB62_RS04715	COG0582	viral genome integration into host DNA
FOB62_RS04830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB62_RS04850	COG0201	protein transport
FOB62_RS04855	COG0200	Binds to the 23S rRNA
FOB62_RS04955	COG0051	transcription antitermination factor activity, RNA binding
FOB62_RS04975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOB62_RS04980	COG1064	alcohol dehydrogenase
FOB62_RS04985	COG1012	belongs to the aldehyde dehydrogenase family
FOB62_RS04985	COG1454	alcohol dehydrogenase
FOB62_RS05000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB62_RS05015	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOB62_RS05035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOB62_RS05040	COG0151	Belongs to the GarS family
FOB62_RS05045	COG3942	CHAP domain
FOB62_RS05060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB62_RS05065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB62_RS05075	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB62_RS05080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOB62_RS05085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB62_RS05105	COG3942	CHAP domain
FOB62_RS05225	COG0531	amino acid
FOB62_RS05230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB62_RS05255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOB62_RS05260	COG2244	polysaccharide biosynthetic process
FOB62_RS05265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB62_RS05275	COG0012	GTP binding
FOB62_RS05290	COG0592	DNA-directed DNA polymerase activity
FOB62_RS05305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB62_RS05340	COG0488	(ABC) transporter
FOB62_RS05345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB62_RS05355	COG0517	IMP dehydrogenase activity
FOB62_RS05355	COG0516	GMP reductase activity
FOB62_RS05380	COG0612	Peptidase, M16
FOB62_RS05390	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB62_RS05410	COG0741	lytic transglycosylase activity
FOB62_RS05420	COG1760	l-serine dehydratase
FOB62_RS05425	COG1760	l-serine dehydratase
FOB62_RS05435	COG2095	MarC family integral membrane protein
FOB62_RS05460	COG0305	Participates in initiation and elongation during chromosome replication
FOB62_RS05475	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOB62_RS05480	COG0582	viral genome integration into host DNA
FOB62_RS05600	COG1511	domain protein
FOB62_RS05655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB62_RS05660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB62_RS05665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOB62_RS05670	COG0488	(ABC) transporter
FOB62_RS05700	COG2814	Major facilitator Superfamily
FOB62_RS05710	COG0519	Catalyzes the synthesis of GMP from XMP
FOB62_RS05730	COG1393	Belongs to the ArsC family
FOB62_RS05735	COG4472	Bacterial protein of unknown function (DUF965)
FOB62_RS05770	COG0602	queuosine metabolic process
FOB62_RS05780	COG2514	catechol 2,3-dioxygenase activity
FOB62_RS05785	COG1733	regulation of RNA biosynthetic process
FOB62_RS05795	COG2188	Transcriptional regulator
FOB62_RS05800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB62_RS05800	COG1263	PTS System
FOB62_RS05805	COG0366	Alpha amylase catalytic
FOB62_RS05810	COG3590	peptidase
FOB62_RS05840	COG0531	amino acid
FOB62_RS05855	COG3404	Formiminotransferase-cyclodeaminase
FOB62_RS05865	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOB62_RS05880	COG0450	alkyl hydroperoxide reductase
FOB62_RS05890	COG4974	Belongs to the 'phage' integrase family
FOB62_RS05925	COG1396	sequence-specific DNA binding
FOB62_RS05930	COG3561	AntA/AntB antirepressor
FOB62_RS05965	COG3935	DnaD domain protein
FOB62_RS06220	COG4463	regulation of RNA biosynthetic process
FOB62_RS06225	COG0542	response to heat
FOB62_RS06240	COG1051	belongs to the nudix hydrolase family
FOB62_RS06255	COG0564	pseudouridine synthase activity
FOB62_RS06270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB62_RS06330	COG1132	(ABC) transporter
FOB62_RS06385	COG3623	hexulose-6-phosphate isomerase
FOB62_RS06405	COG1597	lipid kinase activity
FOB62_RS06410	COG3448	diguanylate cyclase activity
FOB62_RS06410	COG4175	Glycine betaine
FOB62_RS06420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB62_RS06420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB62_RS06425	COG1832	CoA-binding protein
FOB62_RS06450	COG1268	BioY protein
FOB62_RS06455	COG1234	tRNA 3'-trailer cleavage
FOB62_RS06475	COG0789	Transcriptional regulator
FOB62_RS06475	COG4978	Transcriptional regulator
FOB62_RS06495	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOB62_RS06500	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOB62_RS06505	COG1454	alcohol dehydrogenase
FOB62_RS06505	COG1012	belongs to the aldehyde dehydrogenase family
FOB62_RS06510	COG1882	Formate acetyltransferase
FOB62_RS06515	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOB62_RS06545	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FOB62_RS06550	COG4766	ethanolamine catabolic process
FOB62_RS06560	COG1454	alcohol dehydrogenase
FOB62_RS06560	COG1012	belongs to the aldehyde dehydrogenase family
FOB62_RS06565	COG4869	propanediol catabolic process
FOB62_RS06595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB62_RS06630	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB62_RS06635	COG0457	Tetratricopeptide repeat
FOB62_RS06635	COG0705	Rhomboid family
FOB62_RS06645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOB62_RS06665	COG1132	(ABC) transporter
FOB62_RS06670	COG1132	(ABC) transporter
FOB62_RS06680	COG0756	dUTP diphosphatase activity
FOB62_RS06745	COG1847	R3H domain protein
FOB62_RS06775	COG1175	transmembrane transport
FOB62_RS06780	COG0395	ABC-type sugar transport system, permease component
FOB62_RS06795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB62_RS06810	COG1335	isochorismatase
FOB62_RS06815	COG0084	hydrolase, TatD family'
FOB62_RS06840	COG1564	THIamine pyrophosphokinase
FOB62_RS06855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB62_RS06885	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOB62_RS06900	COG0789	Transcriptional regulator
FOB62_RS06905	COG0174	glutamine synthetase
FOB62_RS06910	COG4166	transmembrane transport
FOB62_RS06915	COG0601	transmembrane transport
FOB62_RS06920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB62_RS06925	COG0444	Belongs to the ABC transporter superfamily
FOB62_RS06930	COG4608	Belongs to the ABC transporter superfamily
FOB62_RS06940	COG5503	Protein of unknown function (DUF1447)
FOB62_RS06945	COG1214	PFAM Peptidase M22, glycoprotease
FOB62_RS06980	COG2081	HI0933 family
FOB62_RS06995	COG0789	Transcriptional regulator
FOB62_RS07025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB62_RS07040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOB62_RS07050	COG4209	transmembrane transport
FOB62_RS07055	COG0395	ABC-type sugar transport system, permease component
FOB62_RS07065	COG1653	transport
FOB62_RS07075	COG2153	protein acetylation
FOB62_RS07080	COG1882	Formate acetyltransferase
FOB62_RS07095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB62_RS07100	COG0681	Belongs to the peptidase S26 family
FOB62_RS07125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB62_RS07130	COG3118	belongs to the thioredoxin family
FOB62_RS07135	COG1194	a g-specific adenine glycosylase
FOB62_RS07175	COG0006	proline dipeptidase activity
FOB62_RS07180	COG2131	deaminase
FOB62_RS07200	COG1609	Transcriptional regulator
FOB62_RS07205	COG1621	beta-fructofuranosidase activity
FOB62_RS07210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOB62_RS07210	COG2190	(PTS) system
FOB62_RS07210	COG1263	PTS System
FOB62_RS07215	COG1940	carbohydrate kinase activity
FOB62_RS07220	COG1482	cell wall glycoprotein biosynthetic process
FOB62_RS07240	COG3942	CHAP domain
FOB62_RS07240	COG1388	LysM domain
FOB62_RS07265	COG1120	ATPase activity
FOB62_RS07270	COG4988	ABC transporter
FOB62_RS07275	COG1132	(ABC) transporter
FOB62_RS07290	COG1129	ABC transporter
FOB62_RS07295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB62_RS07300	COG4989	oxidoreductase activity
FOB62_RS07305	COG0252	asparaginase activity
FOB62_RS07310	COG0561	phosphatase activity
FOB62_RS07320	COG0436	Aminotransferase
FOB62_RS07330	COG1335	isochorismatase
FOB62_RS07335	COG1937	Protein conserved in bacteria
FOB62_RS07345	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB62_RS07355	COG0517	IMP dehydrogenase activity
FOB62_RS07360	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOB62_RS07365	COG0574	Belongs to the PEP-utilizing enzyme family
FOB62_RS07365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB62_RS07390	COG2261	transglycosylase associated protein
FOB62_RS07395	COG0588	phosphoglycerate mutase activity
FOB62_RS07410	COG1420	regulation of RNA biosynthetic process
FOB62_RS07430	COG0484	heat shock protein binding
FOB62_RS07435	COG1024	Enoyl-CoA hydratase
FOB62_RS07455	COG2070	2-Nitropropane dioxygenase
FOB62_RS07460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOB62_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
FOB62_RS07470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB62_RS07485	COG0439	Biotin carboxylase
FOB62_RS07515	COG3716	PTS system mannose fructose sorbose family IID component
FOB62_RS07520	COG3715	PTS system
FOB62_RS07530	COG0561	phosphatase activity
FOB62_RS07535	COG2252	PERMEase
FOB62_RS07540	COG0802	atpase or kinase
FOB62_RS07545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB62_RS07550	COG1316	TRANSCRIPTIONal
FOB62_RS07560	COG0537	adenosine 5'-monophosphoramidase activity
FOB62_RS07565	COG1131	(ABC) transporter
FOB62_RS07570	COG4473	ABC transporter
FOB62_RS07595	COG0195	Participates in both transcription termination and antitermination
FOB62_RS07600	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOB62_RS07630	COG2217	Heavy metal translocating P-type atpase
FOB62_RS07650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB62_RS07680	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB62_RS07690	COG2860	membrane
FOB62_RS07695	COG0561	phosphatase activity
FOB62_RS07715	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOB62_RS07725	COG0656	L-ascorbic acid biosynthetic process
FOB62_RS07730	COG1755	Isoprenylcysteine carboxyl methyltransferase
FOB62_RS07765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOB62_RS07770	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB62_RS07795	COG1131	(ABC) transporter
FOB62_RS07830	COG0768	penicillin binding
FOB62_RS07840	COG0513	Belongs to the DEAD box helicase family
FOB62_RS07850	COG0765	amino acid transport
FOB62_RS07855	COG1126	abc transporter atp-binding protein
FOB62_RS07865	COG0492	ferredoxin-NADP+ reductase activity
FOB62_RS07870	COG1113	amino acid transport
FOB62_RS07875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOB62_RS07885	COG3579	cysteine-type endopeptidase activity
FOB62_RS07890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB62_RS07915	COG0116	Belongs to the methyltransferase superfamily
FOB62_RS07950	COG0183	Belongs to the thiolase family
FOB62_RS07975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB62_RS07985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB62_RS07985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB62_RS07995	COG0515	serine threonine protein kinase
FOB62_RS07995	COG2815	serine threonine protein kinase
FOB62_RS08005	COG4585	Histidine kinase
FOB62_RS08010	COG2197	response regulator
FOB62_RS08020	COG1098	S1 RNA binding domain
FOB62_RS08030	COG1739	Uncharacterized protein family UPF0029
FOB62_RS08035	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOB62_RS08040	COG1040	competence protein
FOB62_RS08145	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB62_RS08145	COG1024	Enoyl-CoA hydratase
FOB62_RS08150	COG0183	Belongs to the thiolase family
FOB62_RS08155	COG2070	2-Nitropropane dioxygenase
FOB62_RS08165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB62_RS08180	COG0383	alpha-mannosidase activity
FOB62_RS08195	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOB62_RS08200	COG2723	6-phospho-beta-galactosidase activity
FOB62_RS08220	COG1175	transmembrane transport
FOB62_RS08225	COG0395	ABC-type sugar transport system, permease component
FOB62_RS08230	COG1653	transport
FOB62_RS08240	COG2972	Histidine kinase
FOB62_RS08245	COG2207	Transcriptional regulator
FOB62_RS08245	COG4753	response regulator
FOB62_RS08250	COG3250	beta-galactosidase activity
FOB62_RS08285	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOB62_RS08285	COG1605	Chorismate mutase
FOB62_RS08295	COG0534	Mate efflux family protein
FOB62_RS08320	COG0346	lactoylglutathione lyase activity
FOB62_RS08365	COG1518	maintenance of DNA repeat elements
FOB62_RS08370	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FOB62_RS08375	COG0673	inositol 2-dehydrogenase activity
FOB62_RS08385	COG0785	Cytochrome C biogenesis protein
FOB62_RS08390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB62_RS08405	COG2972	Histidine kinase
FOB62_RS08425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB62_RS08430	COG2235	arginine
FOB62_RS08435	COG0454	-acetyltransferase
FOB62_RS08445	COG1288	antiporter activity
FOB62_RS08450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB62_RS08460	COG0549	Belongs to the carbamate kinase family
FOB62_RS08470	COG0742	ribosomal rna small subunit methyltransferase
FOB62_RS08480	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOB62_RS08485	COG1609	Transcriptional regulator
FOB62_RS08490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB62_RS08495	COG1869	D-ribose catabolic process
FOB62_RS08515	COG4470	Protein conserved in bacteria
FOB62_RS08520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOB62_RS08530	COG1132	(ABC) transporter
FOB62_RS08535	COG1132	(ABC) transporter
FOB62_RS08545	COG0783	Belongs to the Dps family
FOB62_RS08555	COG1940	carbohydrate kinase activity
FOB62_RS08560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOB62_RS08565	COG1217	gtp-binding protein TYPA
FOB62_RS08610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB62_RS08630	COG3599	regulation of cell shape
FOB62_RS08650	COG0542	response to heat
FOB62_RS08655	COG4703	Protein of unknown function (DUF1797)
FOB62_RS08660	COG0765	amino acid transport
FOB62_RS08685	COG0415	Belongs to the DNA photolyase family
FOB62_RS08690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB62_RS08700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB62_RS08720	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOB62_RS08725	COG1438	arginine binding
FOB62_RS08730	COG0497	DNA recombination
FOB62_RS08750	COG2755	lipolytic protein G-D-S-L family
FOB62_RS08775	COG2217	Heavy metal translocating P-type atpase
FOB62_RS08790	COG1827	regulation of RNA biosynthetic process
FOB62_RS08800	COG2116	formate transmembrane transporter activity
FOB62_RS08805	COG0768	penicillin binding
FOB62_RS08820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB62_RS08845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB62_RS08855	COG1464	Belongs to the NlpA lipoprotein family
FOB62_RS08860	COG0513	Belongs to the DEAD box helicase family
FOB62_RS08875	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOB62_RS08880	COG0204	Acyl-transferase
FOB62_RS08885	COG1596	polysaccharide export
FOB62_RS08885	COG1555	photosystem II stabilization
FOB62_RS08890	COG0658	competence protein
FOB62_RS08890	COG2333	competence protein COMEC
FOB62_RS08925	COG1187	pseudouridine synthase activity
FOB62_RS08945	COG0431	NADPH-dependent FMN reductase
FOB62_RS08960	COG2223	nitrite transmembrane transporter activity
FOB62_RS08965	COG4122	O-methyltransferase activity
FOB62_RS08990	COG1476	TRANSCRIPTIONal
FOB62_RS09010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB62_RS09015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB62_RS09020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB62_RS09040	COG0726	polysaccharide deacetylase
FOB62_RS09045	COG0513	Belongs to the DEAD box helicase family
FOB62_RS09065	COG1956	GAF domain-containing protein
FOB62_RS09070	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOB62_RS09080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOB62_RS09080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOB62_RS09100	COG2211	Major facilitator Superfamily
FOB62_RS09110	COG3250	beta-galactosidase activity
FOB62_RS09115	COG2186	Transcriptional regulator
FOB62_RS09120	COG0800	Aldolase
FOB62_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
FOB62_RS09160	COG4109	DRTGG domain
FOB62_RS09190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB62_RS09230	COG1132	(ABC) transporter
FOB62_RS09235	COG1132	(ABC) transporter
FOB62_RS09240	COG1129	ABC transporter
FOB62_RS09345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB62_RS09345	COG0551	DNA topoisomerase type I activity
FOB62_RS09380	COG4581	dead DEAH box helicase
FOB62_RS09395	COG1309	transcriptional regulator
FOB62_RS09400	COG2375	cellular response to nickel ion
FOB62_RS09400	COG1132	(ABC) transporter
FOB62_RS09405	COG1132	(ABC) transporter
FOB62_RS09420	COG1129	ABC transporter
FOB62_RS09425	COG0534	Mate efflux family protein
FOB62_RS09475	COG1464	Belongs to the NlpA lipoprotein family
FOB62_RS09490	COG4619	ABC transporter
FOB62_RS09495	COG0390	transport system, permease component
FOB62_RS09505	COG2814	Major facilitator Superfamily
FOB62_RS09515	COG1187	pseudouridine synthase activity
FOB62_RS09525	COG2309	aminopeptidase activity
FOB62_RS09550	COG2723	6-phospho-beta-galactosidase activity
FOB62_RS09560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB62_RS09560	COG3711	transcriptional antiterminator
FOB62_RS09570	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOB62_RS09580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOB62_RS09585	COG1126	abc transporter atp-binding protein
FOB62_RS09590	COG0765	amino acid transport
FOB62_RS09610	COG1696	Membrane protein involved in D-alanine export
FOB62_RS09620	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOB62_RS09625	COG2182	Extracellular solute-binding protein
FOB62_RS09640	COG3833	ABC-type maltose transport systems, permease component
FOB62_RS09655	COG3833	ABC-type maltose transport systems, permease component
FOB62_RS09665	COG2182	Extracellular solute-binding protein
FOB62_RS09680	COG1609	Transcriptional regulator
FOB62_RS09685	COG1640	4-alpha-glucanotransferase
FOB62_RS09690	COG0058	SHG alpha-glucan phosphorylase activity
FOB62_RS09695	COG0431	NADPH-dependent FMN reductase
FOB62_RS09705	COG1054	Belongs to the UPF0176 family
FOB62_RS09710	COG0572	uridine kinase
FOB62_RS09735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB62_RS09750	COG0300	oxidoreductase activity
FOB62_RS09755	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOB62_RS09755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB62_RS09770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB62_RS09775	COG2384	SAM-dependent methyltransferase
FOB62_RS09790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB62_RS09795	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOB62_RS09805	COG1088	dTDP-glucose 4,6-dehydratase activity
FOB62_RS09820	COG1051	belongs to the nudix hydrolase family
FOB62_RS09825	COG0628	permease
FOB62_RS09830	COG0457	Tetratricopeptide repeat
FOB62_RS09835	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FOB62_RS09855	COG3700	Belongs to the class B bacterial acid phosphatase family
FOB62_RS09885	COG1122	ATPase activity
FOB62_RS09905	COG0488	(ABC) transporter
FOB62_RS09910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOB62_RS09915	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB62_RS09915	COG0022	dehydrogenase e1 component
FOB62_RS09920	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB62_RS09935	COG1695	Transcriptional regulator
FOB62_RS09945	COG0095	Lipoate-protein ligase
FOB62_RS09950	COG3442	glutamine amidotransferase
FOB62_RS09955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB62_RS09960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOB62_RS09980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB62_RS09990	COG0647	UMP catabolic process
FOB62_RS10005	COG1518	maintenance of DNA repeat elements
FOB62_RS10010	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FOB62_RS10070	COG3715	PTS system
FOB62_RS10075	COG3716	PTS system mannose fructose sorbose family IID component
FOB62_RS10080	COG2972	Histidine kinase
FOB62_RS10100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB62_RS10105	COG0110	maltose O-acetyltransferase activity
FOB62_RS10115	COG1011	Hydrolase
FOB62_RS10120	COG1012	belongs to the aldehyde dehydrogenase family
FOB62_RS10145	COG0028	Belongs to the TPP enzyme family
FOB62_RS10150	COG0028	Belongs to the TPP enzyme family
FOB62_RS10160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB62_RS10190	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOB62_RS10230	COG2801	Transposase and inactivated derivatives
FOB62_RS10245	COG0765	amino acid transport
FOB62_RS10265	COG0187	DNA topoisomerase II activity
FOB62_RS10280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB62_RS10300	COG0539	negative regulation of cytoplasmic translation
FOB62_RS10325	COG0398	Pfam SNARE associated Golgi protein
FOB62_RS10335	COG1131	(ABC) transporter
FOB62_RS10340	COG1725	Transcriptional regulator
FOB62_RS10355	COG0469	pyruvate kinase activity
FOB62_RS10370	COG2824	Alkylphosphonate utilization operon protein PhnA
FOB62_RS10375	COG0765	amino acid transport
FOB62_RS10380	COG1126	abc transporter atp-binding protein
FOB62_RS10385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB62_RS10395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOB62_RS10400	COG1115	amino acid carrier protein
FOB62_RS10410	COG2261	transglycosylase associated protein
FOB62_RS10450	COG1136	(ABC) transporter
FOB62_RS10450	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB62_RS10480	COG0196	riboflavin kinase activity
FOB62_RS10495	COG0483	inositol monophosphate 1-phosphatase activity
FOB62_RS10500	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOB62_RS10500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB62_RS10510	COG0573	inorganic phosphate transmembrane transporter activity
FOB62_RS10515	COG0581	inorganic phosphate transmembrane transporter activity
FOB62_RS10530	COG0704	Plays a role in the regulation of phosphate uptake
FOB62_RS10540	COG0745	RESPONSE REGULATOR receiver
FOB62_RS10545	COG5002	protein histidine kinase activity
FOB62_RS10560	COG2813	Specifically methylates the guanine in position
FOB62_RS10565	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOB62_RS10580	COG1744	ABC transporter substrate-binding protein PnrA-like
FOB62_RS10585	COG3845	ABC transporter
FOB62_RS10590	COG4603	Belongs to the binding-protein-dependent transport system permease family
FOB62_RS10595	COG1079	Belongs to the binding-protein-dependent transport system permease family
FOB62_RS10600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB62_RS10605	COG4684	Psort location CytoplasmicMembrane, score
FOB62_RS10610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB62_RS10620	COG0095	Lipoate-protein ligase
FOB62_RS10675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB62_RS10680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB62_RS10685	COG1328	CTP reductase activity
FOB62_RS10685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB62_RS10690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB62_RS10710	COG0488	(ABC) transporter
FOB62_RS10735	COG1272	protein, Hemolysin III
FOB62_RS10745	COG1396	sequence-specific DNA binding
FOB62_RS10780	COG0758	DNA mediated transformation
FOB62_RS10785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB62_RS10835	COG0511	ligase activity, forming carbon-carbon bonds
FOB62_RS10840	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FOB62_RS10860	COG2851	Citrate transporter
FOB62_RS10870	COG0511	ligase activity, forming carbon-carbon bonds
FOB62_RS10875	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FOB62_RS10910	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FOB62_RS10925	COG1136	(ABC) transporter
FOB62_RS10930	COG0577	efflux transmembrane transporter activity
FOB62_RS10935	COG0745	RESPONSE REGULATOR receiver
FOB62_RS10940	COG5002	protein histidine kinase activity
FOB62_RS10950	COG1252	NADH dehydrogenase
FOB62_RS10955	COG0142	geranyltranstransferase activity
FOB62_RS10960	COG4939	FMN-binding domain protein
FOB62_RS10990	COG0662	Cupin 2, conserved barrel domain protein
FOB62_RS10995	COG5002	protein histidine kinase activity
FOB62_RS11025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB62_RS11035	COG2188	Transcriptional regulator
FOB62_RS11100	COG0732	type I restriction modification DNA specificity domain
FOB62_RS11110	COG4974	Belongs to the 'phage' integrase family