locus-tag	class	description
SDSE_RS10645	COG0592	DNA-directed DNA polymerase activity
SDSE_RS10665	COG0012	GTP binding
SDSE_RS10675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SDSE_RS10680	COG2244	polysaccharide biosynthetic process
SDSE_RS10685	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SDSE_RS10710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SDSE_RS10715	COG0531	amino acid
SDSE_RS10835	COG3942	CHAP domain
SDSE_RS10855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SDSE_RS10860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SDSE_RS10865	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SDSE_RS10875	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SDSE_RS10880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SDSE_RS10895	COG3942	CHAP domain
SDSE_RS10900	COG0151	Belongs to the GarS family
SDSE_RS10905	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SDSE_RS10925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SDSE_RS10940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SDSE_RS10955	COG1012	belongs to the aldehyde dehydrogenase family
SDSE_RS10955	COG1454	alcohol dehydrogenase
SDSE_RS10960	COG1064	alcohol dehydrogenase
SDSE_RS10965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SDSE_RS10980	COG0051	transcription antitermination factor activity, RNA binding
SDSE_RS11080	COG0200	Binds to the 23S rRNA
SDSE_RS11085	COG0201	protein transport
SDSE_RS11100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SDSE_RS11205	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SDSE_RS11215	COG1252	NADH dehydrogenase
SDSE_RS11220	COG1271	oxidase subunit
SDSE_RS11225	COG1294	oxidase, subunit
SDSE_RS11230	COG4988	ABC transporter
SDSE_RS11235	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SDSE_RS11240	COG0142	geranyltranstransferase activity
SDSE_RS11255	COG1121	(ABC) transporter
SDSE_RS11260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SDSE_RS11270	COG4499	WXG100 protein secretion system (Wss), protein YukC
SDSE_RS11270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDSE_RS11290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SDSE_RS11295	COG1459	type II secretion system
SDSE_RS11300	COG4537	Required for transformation and DNA binding
SDSE_RS11340	COG1266	CAAX protease self-immunity
SDSE_RS11350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SDSE_RS11355	COG1363	Peptidase, m42
SDSE_RS11365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDSE_RS11370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SDSE_RS11380	COG1428	Deoxynucleoside kinase
SDSE_RS11385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SDSE_RS11440	COG0251	oxidation-reduction process
SDSE_RS11465	COG1744	ABC transporter substrate-binding protein PnrA-like
SDSE_RS11470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDSE_RS11475	COG1349	DNA-binding transcription factor activity
SDSE_RS11480	COG2390	Transcriptional regulator
SDSE_RS11485	COG1447	Phosphotransferase system cellobiose-specific component IIA
SDSE_RS11490	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SDSE_RS11495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SDSE_RS11500	COG1882	Formate acetyltransferase
SDSE_RS11520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SDSE_RS11545	COG3655	Transcriptional regulator
SDSE_RS11560	COG0488	(ABC) transporter
SDSE_RS11610	COG1132	(ABC) transporter
SDSE_RS11680	COG1122	ATPase activity
SDSE_RS11700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SDSE_RS11705	COG0512	Glutamine amidotransferase of anthranilate synthase
SDSE_RS11710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SDSE_RS11745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SDSE_RS11750	COG1609	Transcriptional regulator
SDSE_RS11755	COG1263	PTS System
SDSE_RS11755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDSE_RS11755	COG2190	(PTS) system
SDSE_RS11770	COG1363	Peptidase, m42
SDSE_RS11795	COG1196	nuclear chromosome segregation
SDSE_RS11820	COG3842	ATPase activity
SDSE_RS11830	COG1523	belongs to the glycosyl hydrolase 13 family
SDSE_RS11845	COG1862	Preprotein translocase
SDSE_RS11855	COG4589	Belongs to the CDS family
SDSE_RS11880	COG1846	Transcriptional regulator
SDSE_RS11910	COG3711	transcriptional antiterminator
SDSE_RS11920	COG3037	sugar-specific permease SgaT UlaA
SDSE_RS11925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SDSE_RS11940	COG1045	serine acetyltransferase
SDSE_RS11955	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SDSE_RS11975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDSE_RS11995	COG1476	TRANSCRIPTIONal
SDSE_RS12010	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SDSE_RS12060	COG2274	protein secretion by the type I secretion system
SDSE_RS12065	COG1136	(ABC) transporter
SDSE_RS12115	COG3775	system Galactitol-specific IIC component
SDSE_RS12120	COG3414	Phosphotransferase system galactitol-specific IIB component
SDSE_RS12140	COG0561	phosphatase activity
SDSE_RS12185	COG0527	aspartate kinase activity
SDSE_RS12195	COG0351	phosphomethylpyrimidine kinase
SDSE_RS12200	COG4720	Psort location CytoplasmicMembrane, score
SDSE_RS12210	COG0668	transmembrane transport
SDSE_RS12220	COG0366	Alpha amylase catalytic
SDSE_RS12230	COG3343	RNA polymerase activity
SDSE_RS12245	COG3279	Response regulator of the LytR AlgR family
SDSE_RS12255	COG1346	cytolysis
SDSE_RS12300	COG0765	amino acid transport
SDSE_RS12320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SDSE_RS12330	COG0719	Fe-S assembly protein
SDSE_RS12335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SDSE_RS12350	COG1686	Belongs to the peptidase S11 family
SDSE_RS12355	COG1686	Belongs to the peptidase S11 family
SDSE_RS12360	COG4166	transmembrane transport
SDSE_RS12365	COG0601	transmembrane transport
SDSE_RS12370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SDSE_RS12375	COG0444	Belongs to the ABC transporter superfamily
SDSE_RS12430	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SDSE_RS12435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SDSE_RS12440	COG1534	Rna-binding protein
SDSE_RS12450	COG1713	HD superfamily hydrolase involved in NAD metabolism
SDSE_RS12460	COG0799	negative regulation of ribosome biogenesis
SDSE_RS12465	COG2226	methyltransferase
SDSE_RS12475	COG0789	Transcriptional regulator
SDSE_RS12495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SDSE_RS12505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDSE_RS12515	COG1464	Belongs to the NlpA lipoprotein family
SDSE_RS12520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDSE_RS12535	COG1114	Component of the transport system for branched-chain amino acids
SDSE_RS12545	COG0569	domain protein
SDSE_RS12550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SDSE_RS12560	COG1704	LemA family
SDSE_RS12575	COG0745	RESPONSE REGULATOR receiver
SDSE_RS12580	COG5002	protein histidine kinase activity
SDSE_RS12585	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SDSE_RS12595	COG1484	DNA-dependent DNA replication
SDSE_RS12605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SDSE_RS12625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SDSE_RS12640	COG1254	Belongs to the acylphosphatase family
SDSE_RS12645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDSE_RS12680	COG4175	Glycine betaine
SDSE_RS12700	COG1187	pseudouridine synthase activity
SDSE_RS12715	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SDSE_RS12720	COG0671	phosphoesterase, PA-phosphatase related
SDSE_RS12725	COG1242	4 iron, 4 sulfur cluster binding
SDSE_RS12730	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SDSE_RS12735	COG1253	flavin adenine dinucleotide binding
SDSE_RS12740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDSE_RS12755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDSE_RS12760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDSE_RS12765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SDSE_RS12770	COG1120	ATPase activity
SDSE_RS12780	COG2244	polysaccharide biosynthetic process
SDSE_RS12820	COG0559	Belongs to the binding-protein-dependent transport system permease family
SDSE_RS12830	COG0411	ABC transporter
SDSE_RS12840	COG0517	IMP dehydrogenase activity
SDSE_RS12850	COG0470	DNA polymerase III
SDSE_RS12855	COG1774	PSP1 C-terminal conserved region
SDSE_RS12880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SDSE_RS12895	COG1393	Belongs to the ArsC family
SDSE_RS12910	COG0708	Exodeoxyribonuclease III
SDSE_RS12920	COG1620	l-lactate permease
SDSE_RS12925	COG1304	FMN binding
SDSE_RS12965	COG1114	Component of the transport system for branched-chain amino acids
SDSE_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
SDSE_RS12995	COG0673	inositol 2-dehydrogenase activity
SDSE_RS13020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SDSE_RS13045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SDSE_RS13105	COG1702	phosphate starvation-inducible protein PhoH
SDSE_RS13110	COG1573	uracil-dna glycosylase
SDSE_RS13120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SDSE_RS13130	COG2274	protein secretion by the type I secretion system
SDSE_RS13165	COG3279	Response regulator of the LytR AlgR family
SDSE_RS13215	COG1396	sequence-specific DNA binding
SDSE_RS13230	COG1131	(ABC) transporter
SDSE_RS13240	COG0433	COG0433 Predicted ATPase
SDSE_RS13250	COG2814	Major facilitator Superfamily
SDSE_RS13260	COG0557	exoribonuclease II activity
SDSE_RS13265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SDSE_RS13275	COG0463	Glycosyl transferase, family 2
SDSE_RS13285	COG0346	lactoylglutathione lyase activity
SDSE_RS13290	COG0778	Nitroreductase
SDSE_RS13295	COG0006	proline dipeptidase activity
SDSE_RS13300	COG1609	Transcriptional regulator
SDSE_RS13315	COG0438	transferase activity, transferring glycosyl groups
SDSE_RS13325	COG4555	ABC transporter
SDSE_RS13340	COG2376	Dihydroxyacetone kinase
SDSE_RS13350	COG2376	Dihydroxyacetone kinase
SDSE_RS13355	COG1461	Dihydroxyacetone kinase
SDSE_RS13360	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SDSE_RS13365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDSE_RS13375	COG0183	Belongs to the thiolase family
SDSE_RS13390	COG0765	amino acid transport
SDSE_RS13395	COG0765	amino acid transport
SDSE_RS13400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDSE_RS13410	COG0745	RESPONSE REGULATOR receiver
SDSE_RS13415	COG5002	protein histidine kinase activity
SDSE_RS13420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SDSE_RS13435	COG1196	nuclear chromosome segregation
SDSE_RS13450	COG0561	phosphatase activity
SDSE_RS13455	COG0561	phosphatase activity
SDSE_RS13460	COG0552	protein localization to endoplasmic reticulum
SDSE_RS13465	COG0477	Major facilitator Superfamily
SDSE_RS13470	COG3711	transcriptional antiterminator
SDSE_RS13475	COG2190	(PTS) system
SDSE_RS13475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDSE_RS13475	COG1263	PTS System
SDSE_RS13485	COG3689	TIGRFAM TIGR03943 family protein
SDSE_RS13490	COG0701	Predicted permease
SDSE_RS13505	COG0745	RESPONSE REGULATOR receiver
SDSE_RS13510	COG5002	protein histidine kinase activity
SDSE_RS13515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SDSE_RS13520	COG0573	inorganic phosphate transmembrane transporter activity
SDSE_RS13530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SDSE_RS13535	COG0704	Plays a role in the regulation of phosphate uptake
SDSE_RS13550	COG2183	response to ionizing radiation
SDSE_RS13595	COG0826	peptidase U32
SDSE_RS13600	COG4443	Transcriptional Coactivator p15 (PC4)
SDSE_RS13640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SDSE_RS13675	COG0386	Belongs to the glutathione peroxidase family
SDSE_RS13680	COG1164	Oligoendopeptidase f
SDSE_RS13690	COG0772	Belongs to the SEDS family
SDSE_RS13695	COG1191	sigma factor activity
SDSE_RS13740	COG2801	Transposase and inactivated derivatives
SDSE_RS13780	COG1078	dGTPase activity
SDSE_RS13800	COG1609	Transcriptional regulator
SDSE_RS13815	COG3715	PTS system
SDSE_RS13820	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDSE_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
SDSE_RS13855	COG5492	domain, Protein
SDSE_RS13880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDSE_RS13885	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SDSE_RS13890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SDSE_RS13895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SDSE_RS13900	COG2884	Cell division ATP-binding protein ftsE
SDSE_RS13905	COG2177	Part of the ABC transporter FtsEX involved in
SDSE_RS13915	COG1199	ATP-dependent helicase activity
SDSE_RS13915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDSE_RS13920	COG0436	Aminotransferase
SDSE_RS13925	COG0017	Asparaginyl-tRNA synthetase
SDSE_RS13960	COG2188	Transcriptional regulator
SDSE_RS13965	COG2222	sugar isomerase
SDSE_RS13985	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDSE_RS13985	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDSE_RS13990	COG3715	PTS system
SDSE_RS13995	COG3716	PTS system mannose fructose sorbose family IID component
SDSE_RS14020	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SDSE_RS14025	COG2153	protein acetylation
SDSE_RS14030	COG0625	glutathione transferase activity
SDSE_RS14040	COG0716	FMN binding
SDSE_RS14050	COG0038	chloride channel
SDSE_RS14065	COG0772	Belongs to the SEDS family
SDSE_RS14085	COG0560	Phosphoserine phosphatase
SDSE_RS14125	COG1131	(ABC) transporter
SDSE_RS14145	COG4708	membrane
SDSE_RS14155	COG1597	lipid kinase activity
SDSE_RS14160	COG1523	belongs to the glycosyl hydrolase 13 family
SDSE_RS14165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SDSE_RS14170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SDSE_RS14175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SDSE_RS14265	COG0577	efflux transmembrane transporter activity
SDSE_RS14275	COG2321	neutral zinc metallopeptidase
SDSE_RS14290	COG0436	Aminotransferase
SDSE_RS14305	COG1970	mechanosensitive ion channel activity
SDSE_RS14310	COG0358	DNA primase activity
SDSE_RS14315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SDSE_RS14320	COG2151	metal-sulfur cluster biosynthetic enzyme
SDSE_RS14335	COG1216	Glycosyl transferase, family 2
SDSE_RS14335	COG1442	glycosyl transferase family 8
SDSE_RS14365	COG1216	Glycosyl transferase, family 2
SDSE_RS14425	COG1368	sulfuric ester hydrolase activity
SDSE_RS14430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SDSE_RS14450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SDSE_RS14455	COG0285	dihydrofolate synthase activity
SDSE_RS14465	COG1104	cysteine desulfurase activity
SDSE_RS14495	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SDSE_RS14500	COG0583	DNA-binding transcription factor activity
SDSE_RS14510	COG0564	pseudouridine synthase activity
SDSE_RS14545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDSE_RS14550	COG1136	(ABC) transporter
SDSE_RS14555	COG0577	efflux transmembrane transporter activity
SDSE_RS14565	COG0584	glycerophosphoryl diester phosphodiesterase
SDSE_RS14575	COG1837	Belongs to the UPF0109 family
SDSE_RS14610	COG1349	DNA-binding transcription factor activity
SDSE_RS14615	COG1105	Belongs to the carbohydrate kinase PfkB family
SDSE_RS14620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDSE_RS14620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDSE_RS14620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDSE_RS14625	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDSE_RS14625	COG1388	LysM domain
SDSE_RS14630	COG1388	LysM domain
SDSE_RS14630	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDSE_RS14655	COG0488	(ABC) transporter
SDSE_RS14665	COG1132	(ABC) transporter
SDSE_RS14670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SDSE_RS14675	COG0242	peptide deformylase activity
SDSE_RS14680	COG0737	Belongs to the 5'-nucleotidase family
SDSE_RS14690	COG1132	(ABC) transporter
SDSE_RS14695	COG1132	(ABC) transporter
SDSE_RS14745	COG3425	synthase
SDSE_RS14755	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SDSE_RS14805	COG1686	Belongs to the peptidase S11 family
SDSE_RS14810	COG0726	polysaccharide deacetylase
SDSE_RS14825	COG0285	dihydrofolate synthase activity
SDSE_RS14830	COG0302	gtp cyclohydrolase
SDSE_RS14860	COG1176	ABC-type spermidine putrescine transport system, permease component I
SDSE_RS14865	COG1177	transmembrane transport
SDSE_RS14875	COG4565	transcriptional regulatory protein
SDSE_RS14880	COG3290	protein histidine kinase activity
SDSE_RS14885	COG3493	citrate carrier protein
SDSE_RS14895	COG0038	chloride channel
SDSE_RS14900	COG1917	Cupin 2, conserved barrel domain protein
SDSE_RS14900	COG4977	sequence-specific DNA binding
SDSE_RS14910	COG0628	permease
SDSE_RS14920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SDSE_RS14940	COG1104	cysteine desulfurase activity
SDSE_RS14955	COG2357	RelA SpoT domain protein
SDSE_RS14965	COG0564	pseudouridine synthase activity
SDSE_RS14970	COG0280	phosphate acetyltransferase
SDSE_RS14975	COG4221	oxidoreductase activity
SDSE_RS14990	COG1174	glycine betaine transport
SDSE_RS15005	COG2233	PERMEase
SDSE_RS15030	COG2890	protein-(glutamine-N5) methyltransferase activity
SDSE_RS15035	COG0009	L-threonylcarbamoyladenylate synthase
SDSE_RS15060	COG1132	(ABC) transporter
SDSE_RS15065	COG1132	(ABC) transporter
SDSE_RS15075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SDSE_RS15090	COG3764	Sortase (surface protein transpeptidase)
SDSE_RS15095	COG0346	lactoylglutathione lyase activity
SDSE_RS15135	COG1136	(ABC) transporter
SDSE_RS15140	COG0577	efflux transmembrane transporter activity
SDSE_RS15145	COG0745	RESPONSE REGULATOR receiver
SDSE_RS15150	COG2205	protein histidine kinase activity
SDSE_RS15155	COG3942	CHAP domain
SDSE_RS15155	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDSE_RS15180	COG0803	Belongs to the bacterial solute-binding protein 9 family
SDSE_RS15200	COG1122	ATPase activity
SDSE_RS15210	COG0601	transmembrane transport
SDSE_RS15245	COG2188	Transcriptional regulator
SDSE_RS15255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SDSE_RS15280	COG5002	protein histidine kinase activity
SDSE_RS15285	COG0662	Cupin 2, conserved barrel domain protein
SDSE_RS15320	COG5002	protein histidine kinase activity
SDSE_RS15325	COG0745	RESPONSE REGULATOR receiver
SDSE_RS15330	COG0577	efflux transmembrane transporter activity
SDSE_RS15335	COG1136	(ABC) transporter
SDSE_RS15350	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SDSE_RS15390	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SDSE_RS15395	COG0511	ligase activity, forming carbon-carbon bonds
SDSE_RS15405	COG2851	Citrate transporter
SDSE_RS15425	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SDSE_RS15430	COG0511	ligase activity, forming carbon-carbon bonds
SDSE_RS15475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SDSE_RS15480	COG0758	DNA mediated transformation
SDSE_RS15500	COG1396	sequence-specific DNA binding
SDSE_RS15510	COG1272	protein, Hemolysin III
SDSE_RS15530	COG0488	(ABC) transporter
SDSE_RS15550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SDSE_RS15555	COG1328	CTP reductase activity
SDSE_RS15555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SDSE_RS15560	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SDSE_RS15565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SDSE_RS15630	COG0095	Lipoate-protein ligase
SDSE_RS15640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SDSE_RS15645	COG4684	Psort location CytoplasmicMembrane, score
SDSE_RS15650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SDSE_RS15655	COG1079	Belongs to the binding-protein-dependent transport system permease family
SDSE_RS15660	COG4603	Belongs to the binding-protein-dependent transport system permease family
SDSE_RS15665	COG3845	ABC transporter
SDSE_RS15670	COG1744	ABC transporter substrate-binding protein PnrA-like
SDSE_RS15685	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SDSE_RS15690	COG2813	Specifically methylates the guanine in position
SDSE_RS15705	COG5002	protein histidine kinase activity
SDSE_RS15710	COG0745	RESPONSE REGULATOR receiver
SDSE_RS15720	COG0704	Plays a role in the regulation of phosphate uptake
SDSE_RS15735	COG0581	inorganic phosphate transmembrane transporter activity
SDSE_RS15740	COG0573	inorganic phosphate transmembrane transporter activity
SDSE_RS15750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SDSE_RS15750	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SDSE_RS15755	COG0483	inositol monophosphate 1-phosphatase activity
SDSE_RS15770	COG0196	riboflavin kinase activity
SDSE_RS15800	COG1136	(ABC) transporter
SDSE_RS15800	COG4591	ABC-type transport system involved in lipoprotein release permease component
SDSE_RS15840	COG2261	transglycosylase associated protein
SDSE_RS15855	COG1115	amino acid carrier protein
SDSE_RS15860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SDSE_RS15870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDSE_RS15875	COG1126	abc transporter atp-binding protein
SDSE_RS15880	COG0765	amino acid transport
SDSE_RS15885	COG2824	Alkylphosphonate utilization operon protein PhnA
SDSE_RS15900	COG0469	pyruvate kinase activity
SDSE_RS15915	COG1725	Transcriptional regulator
SDSE_RS15920	COG1131	(ABC) transporter
SDSE_RS15930	COG0398	Pfam SNARE associated Golgi protein
SDSE_RS15950	COG0539	negative regulation of cytoplasmic translation
SDSE_RS15970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SDSE_RS15990	COG0187	DNA topoisomerase II activity
SDSE_RS16010	COG0765	amino acid transport
SDSE_RS16025	COG2801	Transposase and inactivated derivatives
SDSE_RS16065	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SDSE_RS16090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDSE_RS16100	COG0028	Belongs to the TPP enzyme family
SDSE_RS16115	COG0028	Belongs to the TPP enzyme family
SDSE_RS16130	COG1012	belongs to the aldehyde dehydrogenase family
SDSE_RS16135	COG1011	Hydrolase
SDSE_RS16145	COG0701	Predicted permease
SDSE_RS16160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDSE_RS16175	COG2207	Transcriptional regulator
SDSE_RS16175	COG4753	response regulator
SDSE_RS16180	COG2972	Histidine kinase
SDSE_RS16185	COG3716	PTS system mannose fructose sorbose family IID component
SDSE_RS16190	COG3715	PTS system
SDSE_RS16260	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SDSE_RS16265	COG1518	maintenance of DNA repeat elements
SDSE_RS16280	COG0647	UMP catabolic process
SDSE_RS16290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SDSE_RS16310	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SDSE_RS16315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SDSE_RS16320	COG3442	glutamine amidotransferase
SDSE_RS16325	COG0095	Lipoate-protein ligase
SDSE_RS16335	COG1695	Transcriptional regulator
SDSE_RS16350	COG0508	dehydrogenase complex catalyzes the overall conversion of
SDSE_RS16355	COG0508	dehydrogenase complex catalyzes the overall conversion of
SDSE_RS16355	COG0022	dehydrogenase e1 component
SDSE_RS16360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SDSE_RS16365	COG0488	(ABC) transporter
SDSE_RS16385	COG1122	ATPase activity
SDSE_RS16415	COG3700	Belongs to the class B bacterial acid phosphatase family
SDSE_RS16440	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SDSE_RS16445	COG0457	Tetratricopeptide repeat
SDSE_RS16450	COG0628	permease
SDSE_RS16455	COG1051	belongs to the nudix hydrolase family
SDSE_RS16470	COG1088	dTDP-glucose 4,6-dehydratase activity
SDSE_RS16480	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SDSE_RS16485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SDSE_RS16500	COG2384	SAM-dependent methyltransferase
SDSE_RS16505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SDSE_RS16520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SDSE_RS16520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SDSE_RS16525	COG0300	oxidoreductase activity
SDSE_RS16540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SDSE_RS16565	COG1054	Belongs to the UPF0176 family
SDSE_RS16575	COG0431	NADPH-dependent FMN reductase
SDSE_RS16580	COG0058	SHG alpha-glucan phosphorylase activity
SDSE_RS16585	COG1640	4-alpha-glucanotransferase
SDSE_RS16590	COG1609	Transcriptional regulator
SDSE_RS16600	COG2182	Extracellular solute-binding protein
SDSE_RS16610	COG3833	ABC-type maltose transport systems, permease component
SDSE_RS16635	COG0366	Alpha amylase catalytic
SDSE_RS16640	COG2182	Extracellular solute-binding protein
SDSE_RS16645	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SDSE_RS16655	COG1696	Membrane protein involved in D-alanine export
SDSE_RS16675	COG0765	amino acid transport
SDSE_RS16680	COG1126	abc transporter atp-binding protein
SDSE_RS16700	COG2309	aminopeptidase activity
SDSE_RS16715	COG1187	pseudouridine synthase activity
SDSE_RS16725	COG2814	Major facilitator Superfamily
SDSE_RS16735	COG0390	transport system, permease component
SDSE_RS16740	COG4619	ABC transporter
SDSE_RS16770	COG0270	DNA (cytosine-5-)-methyltransferase activity
SDSE_RS16820	COG0534	Mate efflux family protein
SDSE_RS16825	COG1129	ABC transporter
SDSE_RS16840	COG1132	(ABC) transporter
SDSE_RS16845	COG2375	cellular response to nickel ion
SDSE_RS16845	COG1132	(ABC) transporter
SDSE_RS16850	COG1309	transcriptional regulator
SDSE_RS16865	COG4581	dead DEAH box helicase
SDSE_RS16885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SDSE_RS16885	COG0551	DNA topoisomerase type I activity
SDSE_RS16960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SDSE_RS16980	COG0860	N-Acetylmuramoyl-L-alanine amidase
SDSE_RS16980	COG1388	LysM domain
SDSE_RS17055	COG0740	serine-type endopeptidase activity
SDSE_RS17060	COG4695	Portal protein
SDSE_RS17105	COG0270	DNA (cytosine-5-)-methyltransferase activity
SDSE_RS17125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SDSE_RS17170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDSE_RS17170	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDSE_RS17230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SDSE_RS17275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SDSE_RS17285	COG0305	Participates in initiation and elongation during chromosome replication
SDSE_RS17320	COG4109	DRTGG domain
SDSE_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
SDSE_RS17365	COG0800	Aldolase
SDSE_RS17370	COG2186	Transcriptional regulator
SDSE_RS17375	COG3250	beta-galactosidase activity
SDSE_RS17385	COG2211	Major facilitator Superfamily
SDSE_RS17405	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SDSE_RS17405	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SDSE_RS17410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SDSE_RS17415	COG1956	GAF domain-containing protein
SDSE_RS17435	COG0513	Belongs to the DEAD box helicase family
SDSE_RS17440	COG0726	polysaccharide deacetylase
SDSE_RS17460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SDSE_RS17465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SDSE_RS17470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SDSE_RS17490	COG1476	TRANSCRIPTIONal
SDSE_RS17510	COG4122	O-methyltransferase activity
SDSE_RS17515	COG2223	nitrite transmembrane transporter activity
SDSE_RS17530	COG0431	NADPH-dependent FMN reductase
SDSE_RS17550	COG1187	pseudouridine synthase activity
SDSE_RS17585	COG0658	competence protein
SDSE_RS17585	COG2333	competence protein COMEC
SDSE_RS17610	COG0860	N-Acetylmuramoyl-L-alanine amidase
SDSE_RS17610	COG1388	LysM domain
SDSE_RS17680	COG0740	serine-type endopeptidase activity
SDSE_RS17715	COG0270	DNA (cytosine-5-)-methyltransferase activity
SDSE_RS17785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDSE_RS17785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDSE_RS17805	COG1401	restriction endodeoxyribonuclease activity
SDSE_RS17830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SDSE_RS17850	COG0488	(ABC) transporter
SDSE_RS17880	COG1596	polysaccharide export
SDSE_RS17880	COG1555	photosystem II stabilization
SDSE_RS17885	COG0204	Acyl-transferase
SDSE_RS17890	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SDSE_RS17905	COG0513	Belongs to the DEAD box helicase family
SDSE_RS17910	COG1464	Belongs to the NlpA lipoprotein family
SDSE_RS17920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SDSE_RS17940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SDSE_RS17955	COG0768	penicillin binding
SDSE_RS17960	COG2116	formate transmembrane transporter activity
SDSE_RS17970	COG1827	regulation of RNA biosynthetic process
SDSE_RS17985	COG2217	Heavy metal translocating P-type atpase
SDSE_RS18010	COG2755	lipolytic protein G-D-S-L family
SDSE_RS18025	COG0497	DNA recombination
SDSE_RS18030	COG1438	arginine binding
SDSE_RS18035	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SDSE_RS18065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SDSE_RS18070	COG0415	Belongs to the DNA photolyase family
SDSE_RS18095	COG0765	amino acid transport
SDSE_RS18100	COG4703	Protein of unknown function (DUF1797)
SDSE_RS18105	COG0542	response to heat
SDSE_RS18110	COG1051	belongs to the nudix hydrolase family
SDSE_RS18125	COG3599	regulation of cell shape
SDSE_RS18145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SDSE_RS18155	COG0849	cell division
SDSE_RS18185	COG1217	gtp-binding protein TYPA
SDSE_RS18190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SDSE_RS18195	COG1940	carbohydrate kinase activity
SDSE_RS18205	COG0783	Belongs to the Dps family
SDSE_RS18215	COG1132	(ABC) transporter
SDSE_RS18220	COG1132	(ABC) transporter
SDSE_RS18230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SDSE_RS18235	COG4470	Protein conserved in bacteria
SDSE_RS18250	COG1879	ABC-type sugar transport system periplasmic component
SDSE_RS18255	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDSE_RS18265	COG1869	D-ribose catabolic process
SDSE_RS18270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDSE_RS18275	COG1609	Transcriptional regulator
SDSE_RS18280	COG3480	Lon protease (S16) C-terminal proteolytic domain
SDSE_RS18290	COG0742	ribosomal rna small subunit methyltransferase
SDSE_RS18300	COG0549	Belongs to the carbamate kinase family
SDSE_RS18310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDSE_RS18315	COG1288	antiporter activity
SDSE_RS18325	COG0454	-acetyltransferase
SDSE_RS18330	COG2235	arginine
SDSE_RS18335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SDSE_RS18355	COG2972	Histidine kinase
SDSE_RS18370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDSE_RS18375	COG0785	Cytochrome C biogenesis protein
SDSE_RS18385	COG0673	inositol 2-dehydrogenase activity
SDSE_RS18390	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SDSE_RS18395	COG1518	maintenance of DNA repeat elements
SDSE_RS18430	COG5433	transposase activity
SDSE_RS18450	COG0346	lactoylglutathione lyase activity
SDSE_RS18530	COG0433	COG0433 Predicted ATPase
SDSE_RS18565	COG3620	sequence-specific DNA binding
SDSE_RS18580	COG1674	ftsk spoiiie
SDSE_RS18660	COG1605	Chorismate mutase
SDSE_RS18660	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SDSE_RS18690	COG3250	beta-galactosidase activity
SDSE_RS18695	COG4753	response regulator
SDSE_RS18695	COG2207	Transcriptional regulator
SDSE_RS18700	COG2972	Histidine kinase
SDSE_RS18710	COG1653	transport
SDSE_RS18715	COG0395	ABC-type sugar transport system, permease component
SDSE_RS18720	COG1175	transmembrane transport
SDSE_RS18725	COG1940	carbohydrate kinase activity
SDSE_RS18740	COG2723	6-phospho-beta-galactosidase activity
SDSE_RS18745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SDSE_RS18760	COG0383	alpha-mannosidase activity
SDSE_RS18780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SDSE_RS18790	COG2070	2-Nitropropane dioxygenase
SDSE_RS18800	COG1024	Enoyl-CoA hydratase
SDSE_RS18800	COG1250	3-hydroxyacyl-CoA dehydrogenase
SDSE_RS18900	COG1040	competence protein
SDSE_RS18905	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SDSE_RS18910	COG1739	Uncharacterized protein family UPF0029
SDSE_RS18920	COG1098	S1 RNA binding domain
SDSE_RS18930	COG2197	response regulator
SDSE_RS18935	COG4585	Histidine kinase
SDSE_RS18945	COG0515	serine threonine protein kinase
SDSE_RS18945	COG2815	serine threonine protein kinase
SDSE_RS18955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SDSE_RS18955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SDSE_RS18965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SDSE_RS18985	COG0583	DNA-binding transcription factor activity
SDSE_RS18990	COG0183	Belongs to the thiolase family
SDSE_RS18995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SDSE_RS19005	COG1028	Short-chain dehydrogenase reductase Sdr
SDSE_RS19025	COG0116	Belongs to the methyltransferase superfamily
SDSE_RS19045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDSE_RS19050	COG3579	cysteine-type endopeptidase activity
SDSE_RS19060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SDSE_RS19065	COG1113	amino acid transport
SDSE_RS19070	COG0492	ferredoxin-NADP+ reductase activity
SDSE_RS19080	COG1126	abc transporter atp-binding protein
SDSE_RS19085	COG0765	amino acid transport
SDSE_RS19095	COG0513	Belongs to the DEAD box helicase family
SDSE_RS19105	COG0768	penicillin binding
SDSE_RS19135	COG1131	(ABC) transporter
SDSE_RS19160	COG0446	pyridine nucleotide-disulphide oxidoreductase
SDSE_RS19165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDSE_RS19200	COG1755	Isoprenylcysteine carboxyl methyltransferase
SDSE_RS19205	COG0656	L-ascorbic acid biosynthetic process
SDSE_RS19215	COG1283	sodium-dependent phosphate transmembrane transporter activity
SDSE_RS19235	COG0561	phosphatase activity
SDSE_RS19240	COG2860	membrane
SDSE_RS19250	COG1105	Belongs to the carbohydrate kinase PfkB family
SDSE_RS19275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDSE_RS19290	COG2217	Heavy metal translocating P-type atpase
SDSE_RS19320	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SDSE_RS19325	COG0195	Participates in both transcription termination and antitermination
SDSE_RS19350	COG4473	ABC transporter
SDSE_RS19355	COG1131	(ABC) transporter
SDSE_RS19360	COG0537	adenosine 5'-monophosphoramidase activity
SDSE_RS19370	COG1316	TRANSCRIPTIONal
SDSE_RS19375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SDSE_RS19380	COG0802	atpase or kinase
SDSE_RS19385	COG2252	PERMEase
SDSE_RS19390	COG0561	phosphatase activity
SDSE_RS19400	COG3715	PTS system
SDSE_RS19405	COG3716	PTS system mannose fructose sorbose family IID component
SDSE_RS19435	COG0439	Biotin carboxylase
SDSE_RS19450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDSE_RS19455	COG1028	Short-chain dehydrogenase reductase Sdr
SDSE_RS19460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SDSE_RS19465	COG2070	2-Nitropropane dioxygenase
SDSE_RS19485	COG1024	Enoyl-CoA hydratase
SDSE_RS19490	COG0484	heat shock protein binding
SDSE_RS19510	COG1420	regulation of RNA biosynthetic process
SDSE_RS19530	COG0588	phosphoglycerate mutase activity
SDSE_RS19535	COG2261	transglycosylase associated protein
SDSE_RS19540	COG0697	spore germination
SDSE_RS19560	COG0574	Belongs to the PEP-utilizing enzyme family
SDSE_RS19560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SDSE_RS19565	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SDSE_RS19570	COG0517	IMP dehydrogenase activity
SDSE_RS19580	COG0446	pyridine nucleotide-disulphide oxidoreductase
SDSE_RS19590	COG1937	Protein conserved in bacteria
SDSE_RS19595	COG1335	isochorismatase
SDSE_RS19605	COG0436	Aminotransferase
SDSE_RS19615	COG0561	phosphatase activity
SDSE_RS19620	COG0252	asparaginase activity
SDSE_RS19625	COG4989	oxidoreductase activity
SDSE_RS19630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SDSE_RS19635	COG1129	ABC transporter
SDSE_RS19650	COG1132	(ABC) transporter
SDSE_RS19655	COG4988	ABC transporter
SDSE_RS19660	COG1120	ATPase activity
SDSE_RS19685	COG3942	CHAP domain
SDSE_RS19685	COG1388	LysM domain
SDSE_RS19705	COG1482	cell wall glycoprotein biosynthetic process
SDSE_RS19710	COG1940	carbohydrate kinase activity
SDSE_RS19715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDSE_RS19715	COG1263	PTS System
SDSE_RS19715	COG2190	(PTS) system
SDSE_RS19720	COG1621	beta-fructofuranosidase activity
SDSE_RS19725	COG1609	Transcriptional regulator
SDSE_RS19745	COG2131	deaminase
SDSE_RS19750	COG0006	proline dipeptidase activity
SDSE_RS19790	COG1194	a g-specific adenine glycosylase
SDSE_RS19805	COG3118	belongs to the thioredoxin family
SDSE_RS19810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SDSE_RS19835	COG0681	Belongs to the peptidase S26 family
SDSE_RS19840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SDSE_RS19855	COG1882	Formate acetyltransferase
SDSE_RS19860	COG2153	protein acetylation
SDSE_RS19870	COG1653	transport
SDSE_RS19880	COG0395	ABC-type sugar transport system, permease component
SDSE_RS19885	COG4209	transmembrane transport
SDSE_RS19895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SDSE_RS19910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDSE_RS19940	COG0789	Transcriptional regulator
SDSE_RS19955	COG2081	HI0933 family
SDSE_RS19990	COG1214	PFAM Peptidase M22, glycoprotease
SDSE_RS19995	COG5503	Protein of unknown function (DUF1447)
SDSE_RS20005	COG4608	Belongs to the ABC transporter superfamily
SDSE_RS20010	COG0444	Belongs to the ABC transporter superfamily
SDSE_RS20015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SDSE_RS20020	COG0601	transmembrane transport
SDSE_RS20025	COG4166	transmembrane transport
SDSE_RS20030	COG0174	glutamine synthetase
SDSE_RS20035	COG0789	Transcriptional regulator
SDSE_RS20055	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SDSE_RS20085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SDSE_RS20100	COG1564	THIamine pyrophosphokinase
SDSE_RS20125	COG0084	hydrolase, TatD family'
SDSE_RS20135	COG1335	isochorismatase
SDSE_RS20150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SDSE_RS20165	COG0395	ABC-type sugar transport system, permease component
SDSE_RS20170	COG1175	transmembrane transport
SDSE_RS20190	COG1847	R3H domain protein
SDSE_RS20255	COG0756	dUTP diphosphatase activity
SDSE_RS20265	COG1132	(ABC) transporter
SDSE_RS20270	COG1132	(ABC) transporter
SDSE_RS20285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SDSE_RS20295	COG0457	Tetratricopeptide repeat
SDSE_RS20295	COG0705	Rhomboid family
SDSE_RS20300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SDSE_RS20340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDSE_RS20365	COG1234	tRNA 3'-trailer cleavage
SDSE_RS20370	COG1268	BioY protein
SDSE_RS20390	COG1832	CoA-binding protein
SDSE_RS20395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDSE_RS20395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDSE_RS20405	COG3448	diguanylate cyclase activity
SDSE_RS20405	COG4175	Glycine betaine
SDSE_RS20410	COG1597	lipid kinase activity
SDSE_RS20435	COG3623	hexulose-6-phosphate isomerase
SDSE_RS20490	COG1132	(ABC) transporter
SDSE_RS20495	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SDSE_RS20535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDSE_RS20550	COG0564	pseudouridine synthase activity
SDSE_RS20580	COG0542	response to heat
SDSE_RS20585	COG4463	regulation of RNA biosynthetic process
SDSE_RS20615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SDSE_RS20635	COG0450	alkyl hydroperoxide reductase
SDSE_RS20650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SDSE_RS20660	COG3404	Formiminotransferase-cyclodeaminase
SDSE_RS20675	COG0531	amino acid
SDSE_RS20705	COG3590	peptidase
SDSE_RS20710	COG0366	Alpha amylase catalytic
SDSE_RS20715	COG1263	PTS System
SDSE_RS20715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDSE_RS20720	COG2188	Transcriptional regulator
SDSE_RS20740	COG0602	queuosine metabolic process
SDSE_RS20775	COG4472	Bacterial protein of unknown function (DUF965)
SDSE_RS20780	COG1393	Belongs to the ArsC family
SDSE_RS20805	COG0519	Catalyzes the synthesis of GMP from XMP
SDSE_RS20815	COG2814	Major facilitator Superfamily
SDSE_RS20855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDSE_RS20860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDSE_RS20865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDSE_RS20950	COG1511	domain protein
SDSE_RS21080	COG0582	viral genome integration into host DNA
SDSE_RS21085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SDSE_RS21095	COG5433	transposase activity
SDSE_RS21110	COG0305	Participates in initiation and elongation during chromosome replication
SDSE_RS21135	COG2095	MarC family integral membrane protein
SDSE_RS21145	COG1760	l-serine dehydratase
SDSE_RS21150	COG1760	l-serine dehydratase
SDSE_RS21160	COG0741	lytic transglycosylase activity
SDSE_RS21180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SDSE_RS21190	COG0612	Peptidase, M16
SDSE_RS21215	COG0517	IMP dehydrogenase activity
SDSE_RS21215	COG0516	GMP reductase activity
SDSE_RS21225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDSE_RS21230	COG0488	(ABC) transporter
SDSE_RS21265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain