locus-tag	class	description
SDE12394_RS00010	COG0592	DNA-directed DNA polymerase activity
SDE12394_RS00030	COG0012	GTP binding
SDE12394_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SDE12394_RS00045	COG2244	polysaccharide biosynthetic process
SDE12394_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SDE12394_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SDE12394_RS00080	COG0531	amino acid
SDE12394_RS00200	COG3942	CHAP domain
SDE12394_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SDE12394_RS00225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SDE12394_RS00230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SDE12394_RS00240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SDE12394_RS00245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SDE12394_RS00260	COG3942	CHAP domain
SDE12394_RS00265	COG0151	Belongs to the GarS family
SDE12394_RS00270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SDE12394_RS00290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SDE12394_RS00305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SDE12394_RS00320	COG1454	alcohol dehydrogenase
SDE12394_RS00320	COG1012	belongs to the aldehyde dehydrogenase family
SDE12394_RS00325	COG1064	alcohol dehydrogenase
SDE12394_RS00330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SDE12394_RS00350	COG0051	transcription antitermination factor activity, RNA binding
SDE12394_RS00450	COG0200	Binds to the 23S rRNA
SDE12394_RS00455	COG0201	protein transport
SDE12394_RS00470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SDE12394_RS00580	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SDE12394_RS00590	COG1252	NADH dehydrogenase
SDE12394_RS00595	COG1271	oxidase subunit
SDE12394_RS00600	COG1294	oxidase, subunit
SDE12394_RS00605	COG4988	ABC transporter
SDE12394_RS00610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SDE12394_RS00615	COG0142	geranyltranstransferase activity
SDE12394_RS00630	COG1121	(ABC) transporter
SDE12394_RS00635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SDE12394_RS00645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDE12394_RS00645	COG4499	WXG100 protein secretion system (Wss), protein YukC
SDE12394_RS00665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SDE12394_RS00670	COG1459	type II secretion system
SDE12394_RS00675	COG4537	Required for transformation and DNA binding
SDE12394_RS00715	COG1266	CAAX protease self-immunity
SDE12394_RS00725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SDE12394_RS00730	COG1363	Peptidase, m42
SDE12394_RS00740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDE12394_RS00745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SDE12394_RS00755	COG1428	Deoxynucleoside kinase
SDE12394_RS00760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SDE12394_RS00805	COG0251	oxidation-reduction process
SDE12394_RS00830	COG1744	ABC transporter substrate-binding protein PnrA-like
SDE12394_RS00835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDE12394_RS00840	COG1349	DNA-binding transcription factor activity
SDE12394_RS00845	COG2390	Transcriptional regulator
SDE12394_RS00850	COG1447	Phosphotransferase system cellobiose-specific component IIA
SDE12394_RS00855	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SDE12394_RS00860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SDE12394_RS00865	COG1882	Formate acetyltransferase
SDE12394_RS00885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SDE12394_RS00910	COG3655	Transcriptional regulator
SDE12394_RS00925	COG0488	(ABC) transporter
SDE12394_RS00975	COG1132	(ABC) transporter
SDE12394_RS01030	COG1674	ftsk spoiiie
SDE12394_RS01055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SDE12394_RS01060	COG0512	Glutamine amidotransferase of anthranilate synthase
SDE12394_RS01065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SDE12394_RS01080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SDE12394_RS01085	COG1609	Transcriptional regulator
SDE12394_RS01090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDE12394_RS01090	COG2190	(PTS) system
SDE12394_RS01090	COG1263	PTS System
SDE12394_RS01105	COG1363	Peptidase, m42
SDE12394_RS01135	COG0737	Belongs to the 5'-nucleotidase family
SDE12394_RS01160	COG3842	ATPase activity
SDE12394_RS01170	COG1523	belongs to the glycosyl hydrolase 13 family
SDE12394_RS01185	COG1862	Preprotein translocase
SDE12394_RS01195	COG4589	Belongs to the CDS family
SDE12394_RS01220	COG1846	Transcriptional regulator
SDE12394_RS01260	COG1126	abc transporter atp-binding protein
SDE12394_RS01270	COG3711	transcriptional antiterminator
SDE12394_RS01285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SDE12394_RS01300	COG1045	serine acetyltransferase
SDE12394_RS01315	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SDE12394_RS01335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDE12394_RS01355	COG1476	TRANSCRIPTIONal
SDE12394_RS01365	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SDE12394_RS01400	COG0433	COG0433 Predicted ATPase
SDE12394_RS01435	COG4115	mRNA cleavage
SDE12394_RS01445	COG1674	ftsk spoiiie
SDE12394_RS01465	COG3620	sequence-specific DNA binding
SDE12394_RS01485	COG3620	sequence-specific DNA binding
SDE12394_RS01530	COG3775	system Galactitol-specific IIC component
SDE12394_RS01535	COG3414	Phosphotransferase system galactitol-specific IIB component
SDE12394_RS01600	COG0527	aspartate kinase activity
SDE12394_RS01610	COG0351	phosphomethylpyrimidine kinase
SDE12394_RS01615	COG4720	Psort location CytoplasmicMembrane, score
SDE12394_RS01625	COG0668	transmembrane transport
SDE12394_RS01630	COG0366	Alpha amylase catalytic
SDE12394_RS01635	COG0366	Alpha amylase catalytic
SDE12394_RS01645	COG3343	RNA polymerase activity
SDE12394_RS01660	COG3279	Response regulator of the LytR AlgR family
SDE12394_RS01670	COG1346	cytolysis
SDE12394_RS01715	COG0765	amino acid transport
SDE12394_RS01735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SDE12394_RS01745	COG0719	Fe-S assembly protein
SDE12394_RS01750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SDE12394_RS01765	COG1686	Belongs to the peptidase S11 family
SDE12394_RS01775	COG1686	Belongs to the peptidase S11 family
SDE12394_RS01780	COG4166	transmembrane transport
SDE12394_RS01785	COG0601	transmembrane transport
SDE12394_RS01790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SDE12394_RS01795	COG0444	Belongs to the ABC transporter superfamily
SDE12394_RS01850	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SDE12394_RS01855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SDE12394_RS01860	COG1534	Rna-binding protein
SDE12394_RS01870	COG1713	HD superfamily hydrolase involved in NAD metabolism
SDE12394_RS01880	COG0799	negative regulation of ribosome biogenesis
SDE12394_RS01885	COG2226	methyltransferase
SDE12394_RS01895	COG0789	Transcriptional regulator
SDE12394_RS01910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SDE12394_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDE12394_RS01930	COG1464	Belongs to the NlpA lipoprotein family
SDE12394_RS01950	COG1114	Component of the transport system for branched-chain amino acids
SDE12394_RS01960	COG0569	domain protein
SDE12394_RS01965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SDE12394_RS01975	COG1704	LemA family
SDE12394_RS01990	COG0745	RESPONSE REGULATOR receiver
SDE12394_RS01995	COG5002	protein histidine kinase activity
SDE12394_RS02000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SDE12394_RS02010	COG1484	DNA-dependent DNA replication
SDE12394_RS02020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SDE12394_RS02040	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SDE12394_RS02055	COG1254	Belongs to the acylphosphatase family
SDE12394_RS02060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDE12394_RS02095	COG4175	Glycine betaine
SDE12394_RS02115	COG1187	pseudouridine synthase activity
SDE12394_RS02130	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SDE12394_RS02135	COG0671	phosphoesterase, PA-phosphatase related
SDE12394_RS02140	COG1242	4 iron, 4 sulfur cluster binding
SDE12394_RS02145	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SDE12394_RS02150	COG1253	flavin adenine dinucleotide binding
SDE12394_RS02155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDE12394_RS02170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDE12394_RS02175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDE12394_RS02180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SDE12394_RS02185	COG1120	ATPase activity
SDE12394_RS02195	COG2244	polysaccharide biosynthetic process
SDE12394_RS02235	COG0559	Belongs to the binding-protein-dependent transport system permease family
SDE12394_RS02245	COG0411	ABC transporter
SDE12394_RS02255	COG0517	IMP dehydrogenase activity
SDE12394_RS02265	COG0470	DNA polymerase III
SDE12394_RS02295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SDE12394_RS02310	COG1393	Belongs to the ArsC family
SDE12394_RS02325	COG1609	Transcriptional regulator
SDE12394_RS02330	COG0561	phosphatase activity
SDE12394_RS02335	COG0708	Exodeoxyribonuclease III
SDE12394_RS02345	COG1620	l-lactate permease
SDE12394_RS02350	COG1304	FMN binding
SDE12394_RS02390	COG1114	Component of the transport system for branched-chain amino acids
SDE12394_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
SDE12394_RS02420	COG0673	inositol 2-dehydrogenase activity
SDE12394_RS02445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SDE12394_RS02470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SDE12394_RS02535	COG1702	phosphate starvation-inducible protein PhoH
SDE12394_RS02540	COG1573	uracil-dna glycosylase
SDE12394_RS02550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SDE12394_RS02610	COG2274	protein secretion by the type I secretion system
SDE12394_RS02670	COG1396	sequence-specific DNA binding
SDE12394_RS02685	COG1131	(ABC) transporter
SDE12394_RS02695	COG0433	COG0433 Predicted ATPase
SDE12394_RS02705	COG2814	Major facilitator Superfamily
SDE12394_RS02715	COG0557	exoribonuclease II activity
SDE12394_RS02720	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SDE12394_RS02730	COG0463	Glycosyl transferase, family 2
SDE12394_RS02740	COG0346	lactoylglutathione lyase activity
SDE12394_RS02745	COG0778	Nitroreductase
SDE12394_RS02750	COG0006	proline dipeptidase activity
SDE12394_RS02755	COG1609	Transcriptional regulator
SDE12394_RS02770	COG0438	transferase activity, transferring glycosyl groups
SDE12394_RS02780	COG4555	ABC transporter
SDE12394_RS02795	COG2376	Dihydroxyacetone kinase
SDE12394_RS02805	COG2376	Dihydroxyacetone kinase
SDE12394_RS02810	COG1461	Dihydroxyacetone kinase
SDE12394_RS02815	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SDE12394_RS02820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDE12394_RS02845	COG0765	amino acid transport
SDE12394_RS02850	COG0765	amino acid transport
SDE12394_RS02865	COG0745	RESPONSE REGULATOR receiver
SDE12394_RS02870	COG5002	protein histidine kinase activity
SDE12394_RS02875	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SDE12394_RS02885	COG1196	nuclear chromosome segregation
SDE12394_RS02900	COG0561	phosphatase activity
SDE12394_RS02905	COG0561	phosphatase activity
SDE12394_RS02910	COG0552	protein localization to endoplasmic reticulum
SDE12394_RS02915	COG0477	Major facilitator Superfamily
SDE12394_RS02920	COG3711	transcriptional antiterminator
SDE12394_RS02925	COG1263	PTS System
SDE12394_RS02925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDE12394_RS02925	COG2190	(PTS) system
SDE12394_RS02935	COG3689	TIGRFAM TIGR03943 family protein
SDE12394_RS02940	COG0701	Predicted permease
SDE12394_RS02960	COG0745	RESPONSE REGULATOR receiver
SDE12394_RS02965	COG5002	protein histidine kinase activity
SDE12394_RS02970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SDE12394_RS02975	COG0573	inorganic phosphate transmembrane transporter activity
SDE12394_RS02985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SDE12394_RS02990	COG0704	Plays a role in the regulation of phosphate uptake
SDE12394_RS03000	COG2183	response to ionizing radiation
SDE12394_RS03045	COG0826	peptidase U32
SDE12394_RS03050	COG4443	Transcriptional Coactivator p15 (PC4)
SDE12394_RS03065	COG0004	ammonium transporteR
SDE12394_RS03070	COG0582	viral genome integration into host DNA
SDE12394_RS03080	COG3942	CHAP domain
SDE12394_RS03080	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDE12394_RS03100	COG0433	COG0433 Predicted ATPase
SDE12394_RS03150	COG1674	ftsk spoiiie
SDE12394_RS03170	COG3620	sequence-specific DNA binding
SDE12394_RS03190	COG3620	sequence-specific DNA binding
SDE12394_RS03195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SDE12394_RS03245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SDE12394_RS03275	COG0386	Belongs to the glutathione peroxidase family
SDE12394_RS03280	COG1164	Oligoendopeptidase f
SDE12394_RS03290	COG0772	Belongs to the SEDS family
SDE12394_RS03295	COG1191	sigma factor activity
SDE12394_RS03335	COG2801	Transposase and inactivated derivatives
SDE12394_RS03380	COG1078	dGTPase activity
SDE12394_RS03400	COG1609	Transcriptional regulator
SDE12394_RS03410	COG3716	PTS system mannose fructose sorbose family IID component
SDE12394_RS03415	COG3715	PTS system
SDE12394_RS03420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDE12394_RS03435	COG1028	Short-chain dehydrogenase reductase Sdr
SDE12394_RS03455	COG5492	domain, Protein
SDE12394_RS03475	COG1396	sequence-specific DNA binding
SDE12394_RS03480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SDE12394_RS03485	COG0542	response to heat
SDE12394_RS03500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDE12394_RS03510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SDE12394_RS03515	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SDE12394_RS03520	COG2884	Cell division ATP-binding protein ftsE
SDE12394_RS03525	COG2177	Part of the ABC transporter FtsEX involved in
SDE12394_RS03535	COG1199	ATP-dependent helicase activity
SDE12394_RS03535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDE12394_RS03540	COG0436	Aminotransferase
SDE12394_RS03545	COG0017	Asparaginyl-tRNA synthetase
SDE12394_RS03580	COG2188	Transcriptional regulator
SDE12394_RS03585	COG2222	sugar isomerase
SDE12394_RS03610	COG3715	PTS system
SDE12394_RS03615	COG3716	PTS system mannose fructose sorbose family IID component
SDE12394_RS03635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SDE12394_RS03640	COG2153	protein acetylation
SDE12394_RS03645	COG0625	glutathione transferase activity
SDE12394_RS03655	COG0716	FMN binding
SDE12394_RS03665	COG0038	chloride channel
SDE12394_RS03680	COG0772	Belongs to the SEDS family
SDE12394_RS03700	COG0560	Phosphoserine phosphatase
SDE12394_RS03740	COG1131	(ABC) transporter
SDE12394_RS03760	COG4708	membrane
SDE12394_RS03770	COG1597	lipid kinase activity
SDE12394_RS03775	COG1523	belongs to the glycosyl hydrolase 13 family
SDE12394_RS03780	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SDE12394_RS03790	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SDE12394_RS03880	COG0577	efflux transmembrane transporter activity
SDE12394_RS03885	COG1136	(ABC) transporter
SDE12394_RS03890	COG2321	neutral zinc metallopeptidase
SDE12394_RS03905	COG0436	Aminotransferase
SDE12394_RS03920	COG1970	mechanosensitive ion channel activity
SDE12394_RS03930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SDE12394_RS03935	COG2151	metal-sulfur cluster biosynthetic enzyme
SDE12394_RS03950	COG1216	Glycosyl transferase, family 2
SDE12394_RS03950	COG1442	glycosyl transferase family 8
SDE12394_RS04005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SDE12394_RS04060	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SDE12394_RS04080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SDE12394_RS04085	COG0285	dihydrofolate synthase activity
SDE12394_RS04095	COG1104	cysteine desulfurase activity
SDE12394_RS04125	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SDE12394_RS04130	COG0583	DNA-binding transcription factor activity
SDE12394_RS04140	COG0564	pseudouridine synthase activity
SDE12394_RS04175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDE12394_RS04180	COG1136	(ABC) transporter
SDE12394_RS04185	COG0577	efflux transmembrane transporter activity
SDE12394_RS04205	COG1837	Belongs to the UPF0109 family
SDE12394_RS04240	COG1349	DNA-binding transcription factor activity
SDE12394_RS04245	COG1105	Belongs to the carbohydrate kinase PfkB family
SDE12394_RS04250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDE12394_RS04250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDE12394_RS04250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDE12394_RS04255	COG1388	LysM domain
SDE12394_RS04255	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDE12394_RS04260	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDE12394_RS04260	COG1388	LysM domain
SDE12394_RS04285	COG0488	(ABC) transporter
SDE12394_RS04295	COG1132	(ABC) transporter
SDE12394_RS04300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SDE12394_RS04305	COG0242	peptide deformylase activity
SDE12394_RS04310	COG0737	Belongs to the 5'-nucleotidase family
SDE12394_RS04320	COG0745	RESPONSE REGULATOR receiver
SDE12394_RS04375	COG3425	synthase
SDE12394_RS04385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SDE12394_RS04430	COG0270	DNA (cytosine-5-)-methyltransferase activity
SDE12394_RS04565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SDE12394_RS04600	COG2217	Heavy metal translocating P-type atpase
SDE12394_RS04605	COG2217	Heavy metal translocating P-type atpase
SDE12394_RS04635	COG2801	Transposase and inactivated derivatives
SDE12394_RS04655	COG3843	relaxase mobilization nuclease domain protein
SDE12394_RS04660	COG1396	sequence-specific DNA binding
SDE12394_RS04670	COG4974	Belongs to the 'phage' integrase family
SDE12394_RS04675	COG1686	Belongs to the peptidase S11 family
SDE12394_RS04680	COG0726	polysaccharide deacetylase
SDE12394_RS04695	COG0285	dihydrofolate synthase activity
SDE12394_RS04700	COG0302	gtp cyclohydrolase
SDE12394_RS04730	COG1176	ABC-type spermidine putrescine transport system, permease component I
SDE12394_RS04735	COG1177	transmembrane transport
SDE12394_RS04745	COG4565	transcriptional regulatory protein
SDE12394_RS04750	COG3290	protein histidine kinase activity
SDE12394_RS04755	COG3493	citrate carrier protein
SDE12394_RS04765	COG0038	chloride channel
SDE12394_RS04770	COG4977	sequence-specific DNA binding
SDE12394_RS04770	COG1917	Cupin 2, conserved barrel domain protein
SDE12394_RS04780	COG0628	permease
SDE12394_RS04790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SDE12394_RS04810	COG1104	cysteine desulfurase activity
SDE12394_RS04840	COG0280	phosphate acetyltransferase
SDE12394_RS04845	COG4221	oxidoreductase activity
SDE12394_RS04860	COG1174	glycine betaine transport
SDE12394_RS04875	COG2233	PERMEase
SDE12394_RS04900	COG2890	protein-(glutamine-N5) methyltransferase activity
SDE12394_RS04905	COG0009	L-threonylcarbamoyladenylate synthase
SDE12394_RS04930	COG1132	(ABC) transporter
SDE12394_RS04935	COG1132	(ABC) transporter
SDE12394_RS04945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SDE12394_RS04960	COG3764	Sortase (surface protein transpeptidase)
SDE12394_RS04965	COG0346	lactoylglutathione lyase activity
SDE12394_RS04980	COG0803	Belongs to the bacterial solute-binding protein 9 family
SDE12394_RS05015	COG1136	(ABC) transporter
SDE12394_RS05020	COG0577	efflux transmembrane transporter activity
SDE12394_RS05025	COG0745	RESPONSE REGULATOR receiver
SDE12394_RS05035	COG3942	CHAP domain
SDE12394_RS05035	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDE12394_RS05065	COG0803	Belongs to the bacterial solute-binding protein 9 family
SDE12394_RS05085	COG1122	ATPase activity
SDE12394_RS05095	COG0601	transmembrane transport
SDE12394_RS05145	COG2188	Transcriptional regulator
SDE12394_RS05155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SDE12394_RS05175	COG0673	inositol 2-dehydrogenase activity
SDE12394_RS05185	COG5002	protein histidine kinase activity
SDE12394_RS05190	COG0662	Cupin 2, conserved barrel domain protein
SDE12394_RS05220	COG4939	FMN-binding domain protein
SDE12394_RS05225	COG0142	geranyltranstransferase activity
SDE12394_RS05230	COG1252	NADH dehydrogenase
SDE12394_RS05240	COG5002	protein histidine kinase activity
SDE12394_RS05245	COG0745	RESPONSE REGULATOR receiver
SDE12394_RS05255	COG1136	(ABC) transporter
SDE12394_RS05270	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SDE12394_RS05310	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SDE12394_RS05315	COG0511	ligase activity, forming carbon-carbon bonds
SDE12394_RS05325	COG2851	Citrate transporter
SDE12394_RS05345	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SDE12394_RS05350	COG0511	ligase activity, forming carbon-carbon bonds
SDE12394_RS05400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SDE12394_RS05405	COG0758	DNA mediated transformation
SDE12394_RS05445	COG1396	sequence-specific DNA binding
SDE12394_RS05455	COG1272	protein, Hemolysin III
SDE12394_RS05475	COG0488	(ABC) transporter
SDE12394_RS05495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SDE12394_RS05500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SDE12394_RS05500	COG1328	CTP reductase activity
SDE12394_RS05505	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SDE12394_RS05510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SDE12394_RS05575	COG0095	Lipoate-protein ligase
SDE12394_RS05585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SDE12394_RS05590	COG4684	Psort location CytoplasmicMembrane, score
SDE12394_RS05595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SDE12394_RS05600	COG1079	Belongs to the binding-protein-dependent transport system permease family
SDE12394_RS05605	COG4603	Belongs to the binding-protein-dependent transport system permease family
SDE12394_RS05610	COG3845	ABC transporter
SDE12394_RS05615	COG1744	ABC transporter substrate-binding protein PnrA-like
SDE12394_RS05630	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SDE12394_RS05635	COG2813	Specifically methylates the guanine in position
SDE12394_RS05650	COG5002	protein histidine kinase activity
SDE12394_RS05655	COG0745	RESPONSE REGULATOR receiver
SDE12394_RS05665	COG0704	Plays a role in the regulation of phosphate uptake
SDE12394_RS05680	COG0581	inorganic phosphate transmembrane transporter activity
SDE12394_RS05685	COG0573	inorganic phosphate transmembrane transporter activity
SDE12394_RS05695	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SDE12394_RS05695	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SDE12394_RS05700	COG0483	inositol monophosphate 1-phosphatase activity
SDE12394_RS05715	COG0196	riboflavin kinase activity
SDE12394_RS05745	COG1136	(ABC) transporter
SDE12394_RS05745	COG4591	ABC-type transport system involved in lipoprotein release permease component
SDE12394_RS05785	COG2261	transglycosylase associated protein
SDE12394_RS05795	COG1115	amino acid carrier protein
SDE12394_RS05800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SDE12394_RS05810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDE12394_RS05815	COG1126	abc transporter atp-binding protein
SDE12394_RS05820	COG0765	amino acid transport
SDE12394_RS05825	COG2824	Alkylphosphonate utilization operon protein PhnA
SDE12394_RS05840	COG0469	pyruvate kinase activity
SDE12394_RS05855	COG1725	Transcriptional regulator
SDE12394_RS05860	COG1131	(ABC) transporter
SDE12394_RS05870	COG0398	Pfam SNARE associated Golgi protein
SDE12394_RS05890	COG0539	negative regulation of cytoplasmic translation
SDE12394_RS05910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SDE12394_RS05925	COG0187	DNA topoisomerase II activity
SDE12394_RS05945	COG0765	amino acid transport
SDE12394_RS05960	COG2801	Transposase and inactivated derivatives
SDE12394_RS06000	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SDE12394_RS06030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDE12394_RS06040	COG0028	Belongs to the TPP enzyme family
SDE12394_RS06045	COG0028	Belongs to the TPP enzyme family
SDE12394_RS06070	COG1012	belongs to the aldehyde dehydrogenase family
SDE12394_RS06075	COG1011	Hydrolase
SDE12394_RS06085	COG0110	maltose O-acetyltransferase activity
SDE12394_RS06090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDE12394_RS06110	COG2972	Histidine kinase
SDE12394_RS06115	COG3716	PTS system mannose fructose sorbose family IID component
SDE12394_RS06120	COG3715	PTS system
SDE12394_RS06180	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SDE12394_RS06185	COG1518	maintenance of DNA repeat elements
SDE12394_RS06210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SDE12394_RS06230	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SDE12394_RS06235	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SDE12394_RS06245	COG0095	Lipoate-protein ligase
SDE12394_RS06255	COG1695	Transcriptional regulator
SDE12394_RS06270	COG0508	dehydrogenase complex catalyzes the overall conversion of
SDE12394_RS06275	COG0508	dehydrogenase complex catalyzes the overall conversion of
SDE12394_RS06275	COG0022	dehydrogenase e1 component
SDE12394_RS06280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SDE12394_RS06285	COG0488	(ABC) transporter
SDE12394_RS06305	COG1122	ATPase activity
SDE12394_RS06335	COG3700	Belongs to the class B bacterial acid phosphatase family
SDE12394_RS06365	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SDE12394_RS06370	COG0457	Tetratricopeptide repeat
SDE12394_RS06375	COG0628	permease
SDE12394_RS06380	COG1051	belongs to the nudix hydrolase family
SDE12394_RS06395	COG1088	dTDP-glucose 4,6-dehydratase activity
SDE12394_RS06405	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SDE12394_RS06410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SDE12394_RS06425	COG2384	SAM-dependent methyltransferase
SDE12394_RS06430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SDE12394_RS06445	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SDE12394_RS06445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SDE12394_RS06450	COG0300	oxidoreductase activity
SDE12394_RS06465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SDE12394_RS06485	COG0572	uridine kinase
SDE12394_RS06490	COG1054	Belongs to the UPF0176 family
SDE12394_RS06500	COG0431	NADPH-dependent FMN reductase
SDE12394_RS06505	COG0058	SHG alpha-glucan phosphorylase activity
SDE12394_RS06510	COG1640	4-alpha-glucanotransferase
SDE12394_RS06525	COG2182	Extracellular solute-binding protein
SDE12394_RS06535	COG3833	ABC-type maltose transport systems, permease component
SDE12394_RS06550	COG3833	ABC-type maltose transport systems, permease component
SDE12394_RS06560	COG0366	Alpha amylase catalytic
SDE12394_RS06565	COG2182	Extracellular solute-binding protein
SDE12394_RS06580	COG1696	Membrane protein involved in D-alanine export
SDE12394_RS06595	COG0765	amino acid transport
SDE12394_RS06600	COG1126	abc transporter atp-binding protein
SDE12394_RS06605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SDE12394_RS06615	COG1447	Phosphotransferase system cellobiose-specific component IIA
SDE12394_RS06625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDE12394_RS06625	COG3711	transcriptional antiterminator
SDE12394_RS06635	COG2723	6-phospho-beta-galactosidase activity
SDE12394_RS06655	COG2309	aminopeptidase activity
SDE12394_RS06675	COG2814	Major facilitator Superfamily
SDE12394_RS06685	COG0390	transport system, permease component
SDE12394_RS06690	COG4619	ABC transporter
SDE12394_RS06705	COG1464	Belongs to the NlpA lipoprotein family
SDE12394_RS06755	COG0534	Mate efflux family protein
SDE12394_RS06760	COG1129	ABC transporter
SDE12394_RS06780	COG1132	(ABC) transporter
SDE12394_RS06780	COG2375	cellular response to nickel ion
SDE12394_RS06835	COG0551	DNA topoisomerase type I activity
SDE12394_RS06835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SDE12394_RS06905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SDE12394_RS06935	COG4109	DRTGG domain
SDE12394_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
SDE12394_RS06975	COG0800	Aldolase
SDE12394_RS06980	COG2186	Transcriptional regulator
SDE12394_RS06985	COG3250	beta-galactosidase activity
SDE12394_RS06995	COG2211	Major facilitator Superfamily
SDE12394_RS07015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SDE12394_RS07015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SDE12394_RS07020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SDE12394_RS07025	COG1956	GAF domain-containing protein
SDE12394_RS07050	COG0726	polysaccharide deacetylase
SDE12394_RS07070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SDE12394_RS07075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SDE12394_RS07080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SDE12394_RS07100	COG1476	TRANSCRIPTIONal
SDE12394_RS07125	COG4122	O-methyltransferase activity
SDE12394_RS07130	COG2223	nitrite transmembrane transporter activity
SDE12394_RS07145	COG0431	NADPH-dependent FMN reductase
SDE12394_RS07170	COG1187	pseudouridine synthase activity
SDE12394_RS07205	COG0658	competence protein
SDE12394_RS07205	COG2333	competence protein COMEC
SDE12394_RS07210	COG1596	polysaccharide export
SDE12394_RS07210	COG1555	photosystem II stabilization
SDE12394_RS07215	COG0204	Acyl-transferase
SDE12394_RS07220	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SDE12394_RS07235	COG0513	Belongs to the DEAD box helicase family
SDE12394_RS07240	COG1464	Belongs to the NlpA lipoprotein family
SDE12394_RS07250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SDE12394_RS07270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SDE12394_RS07285	COG0768	penicillin binding
SDE12394_RS07290	COG2116	formate transmembrane transporter activity
SDE12394_RS07300	COG1827	regulation of RNA biosynthetic process
SDE12394_RS07315	COG2217	Heavy metal translocating P-type atpase
SDE12394_RS07340	COG2755	lipolytic protein G-D-S-L family
SDE12394_RS07360	COG0497	DNA recombination
SDE12394_RS07365	COG1438	arginine binding
SDE12394_RS07370	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SDE12394_RS07390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SDE12394_RS07400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SDE12394_RS07405	COG0415	Belongs to the DNA photolyase family
SDE12394_RS07430	COG0765	amino acid transport
SDE12394_RS07435	COG4703	Protein of unknown function (DUF1797)
SDE12394_RS07440	COG0542	response to heat
SDE12394_RS07460	COG3599	regulation of cell shape
SDE12394_RS07480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SDE12394_RS07520	COG2801	Transposase and inactivated derivatives
SDE12394_RS07530	COG1217	gtp-binding protein TYPA
SDE12394_RS07535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SDE12394_RS07540	COG1940	carbohydrate kinase activity
SDE12394_RS07560	COG1132	(ABC) transporter
SDE12394_RS07565	COG1132	(ABC) transporter
SDE12394_RS07575	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SDE12394_RS07580	COG4470	Protein conserved in bacteria
SDE12394_RS07600	COG1129	ABC transporter
SDE12394_RS07605	COG1869	D-ribose catabolic process
SDE12394_RS07610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDE12394_RS07615	COG1609	Transcriptional regulator
SDE12394_RS07620	COG3480	Lon protease (S16) C-terminal proteolytic domain
SDE12394_RS07630	COG0742	ribosomal rna small subunit methyltransferase
SDE12394_RS07640	COG0549	Belongs to the carbamate kinase family
SDE12394_RS07650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDE12394_RS07655	COG1288	antiporter activity
SDE12394_RS07665	COG0454	-acetyltransferase
SDE12394_RS07670	COG2235	arginine
SDE12394_RS07675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SDE12394_RS07695	COG2972	Histidine kinase
SDE12394_RS07710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDE12394_RS07715	COG0785	Cytochrome C biogenesis protein
SDE12394_RS07725	COG0673	inositol 2-dehydrogenase activity
SDE12394_RS07730	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SDE12394_RS07735	COG1518	maintenance of DNA repeat elements
SDE12394_RS07780	COG0346	lactoylglutathione lyase activity
SDE12394_RS07800	COG0534	Mate efflux family protein
SDE12394_RS07810	COG1605	Chorismate mutase
SDE12394_RS07810	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SDE12394_RS07845	COG3250	beta-galactosidase activity
SDE12394_RS07850	COG4753	response regulator
SDE12394_RS07850	COG2207	Transcriptional regulator
SDE12394_RS07855	COG2972	Histidine kinase
SDE12394_RS07865	COG1653	transport
SDE12394_RS07870	COG0395	ABC-type sugar transport system, permease component
SDE12394_RS07875	COG1175	transmembrane transport
SDE12394_RS07895	COG2723	6-phospho-beta-galactosidase activity
SDE12394_RS07900	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SDE12394_RS07915	COG0383	alpha-mannosidase activity
SDE12394_RS07930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SDE12394_RS07940	COG2070	2-Nitropropane dioxygenase
SDE12394_RS07945	COG0183	Belongs to the thiolase family
SDE12394_RS08050	COG1040	competence protein
SDE12394_RS08060	COG1739	Uncharacterized protein family UPF0029
SDE12394_RS08070	COG1098	S1 RNA binding domain
SDE12394_RS08080	COG2197	response regulator
SDE12394_RS08085	COG4585	Histidine kinase
SDE12394_RS08095	COG0515	serine threonine protein kinase
SDE12394_RS08095	COG2815	serine threonine protein kinase
SDE12394_RS08105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SDE12394_RS08105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SDE12394_RS08115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SDE12394_RS08140	COG0183	Belongs to the thiolase family
SDE12394_RS08145	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SDE12394_RS08155	COG1028	Short-chain dehydrogenase reductase Sdr
SDE12394_RS08175	COG0116	Belongs to the methyltransferase superfamily
SDE12394_RS08195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDE12394_RS08200	COG3579	cysteine-type endopeptidase activity
SDE12394_RS08210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SDE12394_RS08215	COG1113	amino acid transport
SDE12394_RS08220	COG0492	ferredoxin-NADP+ reductase activity
SDE12394_RS08230	COG1126	abc transporter atp-binding protein
SDE12394_RS08235	COG0765	amino acid transport
SDE12394_RS08245	COG0513	Belongs to the DEAD box helicase family
SDE12394_RS08310	COG0446	pyridine nucleotide-disulphide oxidoreductase
SDE12394_RS08315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDE12394_RS08350	COG1755	Isoprenylcysteine carboxyl methyltransferase
SDE12394_RS08355	COG0656	L-ascorbic acid biosynthetic process
SDE12394_RS08365	COG1283	sodium-dependent phosphate transmembrane transporter activity
SDE12394_RS08385	COG0561	phosphatase activity
SDE12394_RS08390	COG2860	membrane
SDE12394_RS08400	COG1105	Belongs to the carbohydrate kinase PfkB family
SDE12394_RS08425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDE12394_RS08440	COG2217	Heavy metal translocating P-type atpase
SDE12394_RS08470	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SDE12394_RS08475	COG0195	Participates in both transcription termination and antitermination
SDE12394_RS08500	COG4473	ABC transporter
SDE12394_RS08505	COG1131	(ABC) transporter
SDE12394_RS08510	COG0537	adenosine 5'-monophosphoramidase activity
SDE12394_RS08525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SDE12394_RS08530	COG0802	atpase or kinase
SDE12394_RS08535	COG2252	PERMEase
SDE12394_RS08540	COG0561	phosphatase activity
SDE12394_RS08550	COG3715	PTS system
SDE12394_RS08555	COG3716	PTS system mannose fructose sorbose family IID component
SDE12394_RS08585	COG0439	Biotin carboxylase
SDE12394_RS08600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDE12394_RS08605	COG1028	Short-chain dehydrogenase reductase Sdr
SDE12394_RS08610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SDE12394_RS08615	COG2070	2-Nitropropane dioxygenase
SDE12394_RS08635	COG1024	Enoyl-CoA hydratase
SDE12394_RS08640	COG0484	heat shock protein binding
SDE12394_RS08660	COG1420	regulation of RNA biosynthetic process
SDE12394_RS08675	COG0588	phosphoglycerate mutase activity
SDE12394_RS08680	COG2261	transglycosylase associated protein
SDE12394_RS08685	COG0697	spore germination
SDE12394_RS08705	COG0574	Belongs to the PEP-utilizing enzyme family
SDE12394_RS08705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SDE12394_RS08710	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SDE12394_RS08715	COG0517	IMP dehydrogenase activity
SDE12394_RS08725	COG0446	pyridine nucleotide-disulphide oxidoreductase
SDE12394_RS08735	COG1937	Protein conserved in bacteria
SDE12394_RS08740	COG1335	isochorismatase
SDE12394_RS08750	COG0436	Aminotransferase
SDE12394_RS08760	COG0561	phosphatase activity
SDE12394_RS08765	COG0252	asparaginase activity
SDE12394_RS08775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SDE12394_RS08780	COG1129	ABC transporter
SDE12394_RS08795	COG1132	(ABC) transporter
SDE12394_RS08805	COG1120	ATPase activity
SDE12394_RS08830	COG3942	CHAP domain
SDE12394_RS08830	COG1388	LysM domain
SDE12394_RS08850	COG1482	cell wall glycoprotein biosynthetic process
SDE12394_RS08855	COG1940	carbohydrate kinase activity
SDE12394_RS08860	COG2190	(PTS) system
SDE12394_RS08860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDE12394_RS08860	COG1263	PTS System
SDE12394_RS08870	COG1609	Transcriptional regulator
SDE12394_RS08890	COG2131	deaminase
SDE12394_RS08895	COG0006	proline dipeptidase activity
SDE12394_RS08935	COG1194	a g-specific adenine glycosylase
SDE12394_RS08940	COG3118	belongs to the thioredoxin family
SDE12394_RS08945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SDE12394_RS08970	COG0681	Belongs to the peptidase S26 family
SDE12394_RS08975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SDE12394_RS08990	COG1882	Formate acetyltransferase
SDE12394_RS08995	COG2153	protein acetylation
SDE12394_RS09005	COG1653	transport
SDE12394_RS09015	COG0395	ABC-type sugar transport system, permease component
SDE12394_RS09020	COG4209	transmembrane transport
SDE12394_RS09030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SDE12394_RS09045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDE12394_RS09075	COG0789	Transcriptional regulator
SDE12394_RS09090	COG2081	HI0933 family
SDE12394_RS09125	COG1214	PFAM Peptidase M22, glycoprotease
SDE12394_RS09130	COG5503	Protein of unknown function (DUF1447)
SDE12394_RS09145	COG0444	Belongs to the ABC transporter superfamily
SDE12394_RS09150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SDE12394_RS09155	COG0601	transmembrane transport
SDE12394_RS09160	COG4166	transmembrane transport
SDE12394_RS09165	COG0174	glutamine synthetase
SDE12394_RS09170	COG0789	Transcriptional regulator
SDE12394_RS09190	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SDE12394_RS09220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SDE12394_RS09235	COG1564	THIamine pyrophosphokinase
SDE12394_RS09260	COG0084	hydrolase, TatD family'
SDE12394_RS09265	COG1335	isochorismatase
SDE12394_RS09280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SDE12394_RS09295	COG0395	ABC-type sugar transport system, permease component
SDE12394_RS09300	COG1175	transmembrane transport
SDE12394_RS09320	COG1847	R3H domain protein
SDE12394_RS09385	COG0756	dUTP diphosphatase activity
SDE12394_RS09395	COG1132	(ABC) transporter
SDE12394_RS09400	COG1132	(ABC) transporter
SDE12394_RS09415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SDE12394_RS09430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SDE12394_RS09465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDE12394_RS09490	COG4869	propanediol catabolic process
SDE12394_RS09495	COG1454	alcohol dehydrogenase
SDE12394_RS09495	COG1012	belongs to the aldehyde dehydrogenase family
SDE12394_RS09505	COG4766	ethanolamine catabolic process
SDE12394_RS09510	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SDE12394_RS09540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDE12394_RS09545	COG1882	Formate acetyltransferase
SDE12394_RS09550	COG1012	belongs to the aldehyde dehydrogenase family
SDE12394_RS09550	COG1454	alcohol dehydrogenase
SDE12394_RS09555	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SDE12394_RS09560	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SDE12394_RS09580	COG4978	Transcriptional regulator
SDE12394_RS09580	COG0789	Transcriptional regulator
SDE12394_RS09600	COG1234	tRNA 3'-trailer cleavage
SDE12394_RS09605	COG1268	BioY protein
SDE12394_RS09625	COG1832	CoA-binding protein
SDE12394_RS09630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDE12394_RS09630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDE12394_RS09640	COG3448	diguanylate cyclase activity
SDE12394_RS09640	COG4175	Glycine betaine
SDE12394_RS09645	COG1597	lipid kinase activity
SDE12394_RS09670	COG3623	hexulose-6-phosphate isomerase
SDE12394_RS09725	COG1132	(ABC) transporter
SDE12394_RS09730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SDE12394_RS09775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDE12394_RS09790	COG0564	pseudouridine synthase activity
SDE12394_RS09805	COG1051	belongs to the nudix hydrolase family
SDE12394_RS09820	COG0542	response to heat
SDE12394_RS09825	COG4463	regulation of RNA biosynthetic process
SDE12394_RS09850	COG0450	alkyl hydroperoxide reductase
SDE12394_RS09865	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SDE12394_RS09875	COG3404	Formiminotransferase-cyclodeaminase
SDE12394_RS09890	COG0531	amino acid
SDE12394_RS09920	COG3590	peptidase
SDE12394_RS09925	COG0366	Alpha amylase catalytic
SDE12394_RS09930	COG1263	PTS System
SDE12394_RS09930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDE12394_RS09935	COG2188	Transcriptional regulator
SDE12394_RS09940	COG1733	regulation of RNA biosynthetic process
SDE12394_RS09945	COG2514	catechol 2,3-dioxygenase activity
SDE12394_RS09990	COG4472	Bacterial protein of unknown function (DUF965)
SDE12394_RS09995	COG1393	Belongs to the ArsC family
SDE12394_RS10015	COG0519	Catalyzes the synthesis of GMP from XMP
SDE12394_RS10025	COG2814	Major facilitator Superfamily
SDE12394_RS10055	COG0488	(ABC) transporter
SDE12394_RS10060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDE12394_RS10065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDE12394_RS10180	COG1511	domain protein
SDE12394_RS10310	COG0582	viral genome integration into host DNA
SDE12394_RS10315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SDE12394_RS10330	COG0305	Participates in initiation and elongation during chromosome replication
SDE12394_RS10355	COG2095	MarC family integral membrane protein
SDE12394_RS10365	COG1760	l-serine dehydratase
SDE12394_RS10370	COG1760	l-serine dehydratase
SDE12394_RS10400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SDE12394_RS10410	COG0612	Peptidase, M16
SDE12394_RS10435	COG0516	GMP reductase activity
SDE12394_RS10435	COG0517	IMP dehydrogenase activity
SDE12394_RS10445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDE12394_RS10450	COG0488	(ABC) transporter
SDE12394_RS10485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SDE12394_RS10515	COG0542	response to heat