locus-tag	class	description
SDEG_RS00010	COG0592	DNA-directed DNA polymerase activity
SDEG_RS00030	COG0012	GTP binding
SDEG_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SDEG_RS00045	COG2244	polysaccharide biosynthetic process
SDEG_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SDEG_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SDEG_RS00080	COG0531	amino acid
SDEG_RS00195	COG3942	CHAP domain
SDEG_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SDEG_RS00220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SDEG_RS00225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SDEG_RS00235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SDEG_RS00240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SDEG_RS00255	COG3942	CHAP domain
SDEG_RS00260	COG0151	Belongs to the GarS family
SDEG_RS00265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SDEG_RS00285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SDEG_RS00295	COG2255	four-way junction helicase activity
SDEG_RS00300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SDEG_RS00315	COG1012	belongs to the aldehyde dehydrogenase family
SDEG_RS00315	COG1454	alcohol dehydrogenase
SDEG_RS00320	COG1064	alcohol dehydrogenase
SDEG_RS00325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SDEG_RS00340	COG0051	transcription antitermination factor activity, RNA binding
SDEG_RS00440	COG0200	Binds to the 23S rRNA
SDEG_RS00445	COG0201	protein transport
SDEG_RS00460	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SDEG_RS00570	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SDEG_RS00580	COG1252	NADH dehydrogenase
SDEG_RS00585	COG1271	oxidase subunit
SDEG_RS00590	COG1294	oxidase, subunit
SDEG_RS00595	COG4988	ABC transporter
SDEG_RS00600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SDEG_RS00605	COG0142	geranyltranstransferase activity
SDEG_RS00620	COG1121	(ABC) transporter
SDEG_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SDEG_RS00635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDEG_RS00635	COG4499	WXG100 protein secretion system (Wss), protein YukC
SDEG_RS00655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SDEG_RS00660	COG1459	type II secretion system
SDEG_RS00665	COG4537	Required for transformation and DNA binding
SDEG_RS00705	COG1266	CAAX protease self-immunity
SDEG_RS00715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SDEG_RS00720	COG1363	Peptidase, m42
SDEG_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDEG_RS00735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SDEG_RS00745	COG1428	Deoxynucleoside kinase
SDEG_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SDEG_RS00795	COG0251	oxidation-reduction process
SDEG_RS00820	COG1744	ABC transporter substrate-binding protein PnrA-like
SDEG_RS00825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDEG_RS00830	COG1349	DNA-binding transcription factor activity
SDEG_RS00835	COG2390	Transcriptional regulator
SDEG_RS00840	COG1447	Phosphotransferase system cellobiose-specific component IIA
SDEG_RS00845	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SDEG_RS00850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SDEG_RS00855	COG1882	Formate acetyltransferase
SDEG_RS00875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SDEG_RS00900	COG3655	Transcriptional regulator
SDEG_RS00915	COG0488	(ABC) transporter
SDEG_RS00970	COG1132	(ABC) transporter
SDEG_RS01040	COG1122	ATPase activity
SDEG_RS01060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SDEG_RS01065	COG0512	Glutamine amidotransferase of anthranilate synthase
SDEG_RS01070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SDEG_RS01085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SDEG_RS01090	COG1609	Transcriptional regulator
SDEG_RS01095	COG2190	(PTS) system
SDEG_RS01095	COG1263	PTS System
SDEG_RS01095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDEG_RS01110	COG1363	Peptidase, m42
SDEG_RS01160	COG3842	ATPase activity
SDEG_RS01170	COG1523	belongs to the glycosyl hydrolase 13 family
SDEG_RS01185	COG1862	Preprotein translocase
SDEG_RS01195	COG4589	Belongs to the CDS family
SDEG_RS01220	COG1846	Transcriptional regulator
SDEG_RS01250	COG3711	transcriptional antiterminator
SDEG_RS01265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SDEG_RS01280	COG1045	serine acetyltransferase
SDEG_RS01295	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SDEG_RS01315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDEG_RS01335	COG1476	TRANSCRIPTIONal
SDEG_RS01345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SDEG_RS01355	COG4974	Belongs to the 'phage' integrase family
SDEG_RS01490	COG3775	system Galactitol-specific IIC component
SDEG_RS01495	COG3414	Phosphotransferase system galactitol-specific IIB component
SDEG_RS01515	COG0561	phosphatase activity
SDEG_RS01555	COG0527	aspartate kinase activity
SDEG_RS01565	COG0351	phosphomethylpyrimidine kinase
SDEG_RS01570	COG4720	Psort location CytoplasmicMembrane, score
SDEG_RS01580	COG0668	transmembrane transport
SDEG_RS01585	COG0366	Alpha amylase catalytic
SDEG_RS01590	COG0366	Alpha amylase catalytic
SDEG_RS01600	COG3343	RNA polymerase activity
SDEG_RS01615	COG3279	Response regulator of the LytR AlgR family
SDEG_RS01625	COG1346	cytolysis
SDEG_RS01675	COG0765	amino acid transport
SDEG_RS01695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SDEG_RS01705	COG0719	Fe-S assembly protein
SDEG_RS01710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SDEG_RS01725	COG1686	Belongs to the peptidase S11 family
SDEG_RS01730	COG1686	Belongs to the peptidase S11 family
SDEG_RS01735	COG4166	transmembrane transport
SDEG_RS01740	COG0601	transmembrane transport
SDEG_RS01745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SDEG_RS01750	COG0444	Belongs to the ABC transporter superfamily
SDEG_RS01805	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SDEG_RS01810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SDEG_RS01815	COG1534	Rna-binding protein
SDEG_RS01825	COG1713	HD superfamily hydrolase involved in NAD metabolism
SDEG_RS01835	COG0799	negative regulation of ribosome biogenesis
SDEG_RS01840	COG2226	methyltransferase
SDEG_RS01850	COG0789	Transcriptional regulator
SDEG_RS01870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SDEG_RS01880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDEG_RS01890	COG1464	Belongs to the NlpA lipoprotein family
SDEG_RS01895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDEG_RS01910	COG1114	Component of the transport system for branched-chain amino acids
SDEG_RS01920	COG0569	domain protein
SDEG_RS01925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SDEG_RS01935	COG1704	LemA family
SDEG_RS01950	COG0745	RESPONSE REGULATOR receiver
SDEG_RS01955	COG5002	protein histidine kinase activity
SDEG_RS01960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SDEG_RS01970	COG1484	DNA-dependent DNA replication
SDEG_RS01980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SDEG_RS02000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SDEG_RS02015	COG1254	Belongs to the acylphosphatase family
SDEG_RS02020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDEG_RS02055	COG4175	Glycine betaine
SDEG_RS02075	COG1187	pseudouridine synthase activity
SDEG_RS02090	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SDEG_RS02095	COG0671	phosphoesterase, PA-phosphatase related
SDEG_RS02100	COG1242	4 iron, 4 sulfur cluster binding
SDEG_RS02105	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SDEG_RS02110	COG1253	flavin adenine dinucleotide binding
SDEG_RS02115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDEG_RS02130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDEG_RS02135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SDEG_RS02140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SDEG_RS02145	COG1120	ATPase activity
SDEG_RS02155	COG2244	polysaccharide biosynthetic process
SDEG_RS02195	COG0559	Belongs to the binding-protein-dependent transport system permease family
SDEG_RS02205	COG0411	ABC transporter
SDEG_RS02215	COG0517	IMP dehydrogenase activity
SDEG_RS02225	COG0470	DNA polymerase III
SDEG_RS02230	COG1774	PSP1 C-terminal conserved region
SDEG_RS02255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SDEG_RS02270	COG1393	Belongs to the ArsC family
SDEG_RS02285	COG1609	Transcriptional regulator
SDEG_RS02290	COG0561	phosphatase activity
SDEG_RS02295	COG0708	Exodeoxyribonuclease III
SDEG_RS02305	COG1620	l-lactate permease
SDEG_RS02310	COG1304	FMN binding
SDEG_RS02350	COG1114	Component of the transport system for branched-chain amino acids
SDEG_RS02370	COG1028	Short-chain dehydrogenase reductase Sdr
SDEG_RS02385	COG0673	inositol 2-dehydrogenase activity
SDEG_RS02410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SDEG_RS02435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SDEG_RS02505	COG1702	phosphate starvation-inducible protein PhoH
SDEG_RS02510	COG1573	uracil-dna glycosylase
SDEG_RS02520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SDEG_RS02530	COG2274	protein secretion by the type I secretion system
SDEG_RS02560	COG3279	Response regulator of the LytR AlgR family
SDEG_RS02575	COG2274	protein secretion by the type I secretion system
SDEG_RS02630	COG1396	sequence-specific DNA binding
SDEG_RS02645	COG1131	(ABC) transporter
SDEG_RS02655	COG0433	COG0433 Predicted ATPase
SDEG_RS02665	COG2814	Major facilitator Superfamily
SDEG_RS02675	COG0557	exoribonuclease II activity
SDEG_RS02680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SDEG_RS02690	COG0463	Glycosyl transferase, family 2
SDEG_RS02700	COG0346	lactoylglutathione lyase activity
SDEG_RS02705	COG0778	Nitroreductase
SDEG_RS02710	COG0006	proline dipeptidase activity
SDEG_RS02715	COG1609	Transcriptional regulator
SDEG_RS02730	COG0438	transferase activity, transferring glycosyl groups
SDEG_RS02740	COG4555	ABC transporter
SDEG_RS02760	COG2376	Dihydroxyacetone kinase
SDEG_RS02770	COG2376	Dihydroxyacetone kinase
SDEG_RS02775	COG1461	Dihydroxyacetone kinase
SDEG_RS02780	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SDEG_RS02785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDEG_RS02795	COG0183	Belongs to the thiolase family
SDEG_RS02815	COG0765	amino acid transport
SDEG_RS02820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDEG_RS02830	COG0745	RESPONSE REGULATOR receiver
SDEG_RS02835	COG5002	protein histidine kinase activity
SDEG_RS02840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SDEG_RS02850	COG1196	nuclear chromosome segregation
SDEG_RS02870	COG0561	phosphatase activity
SDEG_RS02875	COG0552	protein localization to endoplasmic reticulum
SDEG_RS02885	COG3711	transcriptional antiterminator
SDEG_RS02890	COG1263	PTS System
SDEG_RS02890	COG2190	(PTS) system
SDEG_RS02890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDEG_RS02900	COG3689	TIGRFAM TIGR03943 family protein
SDEG_RS02905	COG0701	Predicted permease
SDEG_RS02920	COG0745	RESPONSE REGULATOR receiver
SDEG_RS02925	COG5002	protein histidine kinase activity
SDEG_RS02930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SDEG_RS02935	COG0573	inorganic phosphate transmembrane transporter activity
SDEG_RS02945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SDEG_RS02950	COG0704	Plays a role in the regulation of phosphate uptake
SDEG_RS02965	COG2183	response to ionizing radiation
SDEG_RS03010	COG0826	peptidase U32
SDEG_RS03015	COG4443	Transcriptional Coactivator p15 (PC4)
SDEG_RS03030	COG0004	ammonium transporteR
SDEG_RS03055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SDEG_RS03080	COG0386	Belongs to the glutathione peroxidase family
SDEG_RS03085	COG1164	Oligoendopeptidase f
SDEG_RS03095	COG0772	Belongs to the SEDS family
SDEG_RS03100	COG1191	sigma factor activity
SDEG_RS03135	COG2801	Transposase and inactivated derivatives
SDEG_RS03175	COG1078	dGTPase activity
SDEG_RS03195	COG1609	Transcriptional regulator
SDEG_RS03205	COG3716	PTS system mannose fructose sorbose family IID component
SDEG_RS03210	COG3715	PTS system
SDEG_RS03215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDEG_RS03230	COG1028	Short-chain dehydrogenase reductase Sdr
SDEG_RS03250	COG5492	domain, Protein
SDEG_RS03275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDEG_RS03280	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SDEG_RS03285	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SDEG_RS03290	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SDEG_RS03295	COG2884	Cell division ATP-binding protein ftsE
SDEG_RS03300	COG2177	Part of the ABC transporter FtsEX involved in
SDEG_RS03310	COG1199	ATP-dependent helicase activity
SDEG_RS03310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDEG_RS03315	COG0436	Aminotransferase
SDEG_RS03320	COG0017	Asparaginyl-tRNA synthetase
SDEG_RS03355	COG2188	Transcriptional regulator
SDEG_RS03360	COG2222	sugar isomerase
SDEG_RS03380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDEG_RS03380	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDEG_RS03385	COG3715	PTS system
SDEG_RS03390	COG3716	PTS system mannose fructose sorbose family IID component
SDEG_RS03415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SDEG_RS03420	COG2153	protein acetylation
SDEG_RS03425	COG0625	glutathione transferase activity
SDEG_RS03435	COG0716	FMN binding
SDEG_RS03445	COG0038	chloride channel
SDEG_RS03460	COG0772	Belongs to the SEDS family
SDEG_RS03480	COG0560	Phosphoserine phosphatase
SDEG_RS03520	COG1131	(ABC) transporter
SDEG_RS03540	COG4708	membrane
SDEG_RS03550	COG1597	lipid kinase activity
SDEG_RS03555	COG1523	belongs to the glycosyl hydrolase 13 family
SDEG_RS03560	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SDEG_RS03565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SDEG_RS03570	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SDEG_RS03660	COG0577	efflux transmembrane transporter activity
SDEG_RS03670	COG2321	neutral zinc metallopeptidase
SDEG_RS03685	COG0436	Aminotransferase
SDEG_RS03700	COG1970	mechanosensitive ion channel activity
SDEG_RS03705	COG0358	DNA primase activity
SDEG_RS03710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SDEG_RS03715	COG2151	metal-sulfur cluster biosynthetic enzyme
SDEG_RS03730	COG1216	Glycosyl transferase, family 2
SDEG_RS03730	COG1442	glycosyl transferase family 8
SDEG_RS03770	COG0463	Glycosyl transferase, family 2
SDEG_RS03785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SDEG_RS03835	COG1368	sulfuric ester hydrolase activity
SDEG_RS03840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SDEG_RS03860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SDEG_RS03865	COG0285	dihydrofolate synthase activity
SDEG_RS03875	COG1104	cysteine desulfurase activity
SDEG_RS03905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SDEG_RS03910	COG0583	DNA-binding transcription factor activity
SDEG_RS03920	COG0564	pseudouridine synthase activity
SDEG_RS03955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDEG_RS03960	COG1136	(ABC) transporter
SDEG_RS03965	COG0577	efflux transmembrane transporter activity
SDEG_RS03975	COG0584	glycerophosphoryl diester phosphodiesterase
SDEG_RS03985	COG1837	Belongs to the UPF0109 family
SDEG_RS04020	COG1349	DNA-binding transcription factor activity
SDEG_RS04025	COG1105	Belongs to the carbohydrate kinase PfkB family
SDEG_RS04030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDEG_RS04030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDEG_RS04030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDEG_RS04035	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDEG_RS04035	COG1388	LysM domain
SDEG_RS04040	COG1388	LysM domain
SDEG_RS04040	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDEG_RS04065	COG0488	(ABC) transporter
SDEG_RS04075	COG1132	(ABC) transporter
SDEG_RS04080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SDEG_RS04085	COG0242	peptide deformylase activity
SDEG_RS04090	COG0737	Belongs to the 5'-nucleotidase family
SDEG_RS04100	COG0745	RESPONSE REGULATOR receiver
SDEG_RS04120	COG1132	(ABC) transporter
SDEG_RS04125	COG1132	(ABC) transporter
SDEG_RS04185	COG3425	synthase
SDEG_RS04200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SDEG_RS04245	COG1686	Belongs to the peptidase S11 family
SDEG_RS04250	COG0726	polysaccharide deacetylase
SDEG_RS04265	COG0285	dihydrofolate synthase activity
SDEG_RS04270	COG0302	gtp cyclohydrolase
SDEG_RS04300	COG1176	ABC-type spermidine putrescine transport system, permease component I
SDEG_RS04305	COG1177	transmembrane transport
SDEG_RS04315	COG4565	transcriptional regulatory protein
SDEG_RS04320	COG3290	protein histidine kinase activity
SDEG_RS04325	COG3493	citrate carrier protein
SDEG_RS04335	COG0038	chloride channel
SDEG_RS04340	COG2207	Transcriptional regulator
SDEG_RS04350	COG0628	permease
SDEG_RS04360	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SDEG_RS04380	COG1104	cysteine desulfurase activity
SDEG_RS04395	COG2357	RelA SpoT domain protein
SDEG_RS04405	COG0564	pseudouridine synthase activity
SDEG_RS04410	COG0280	phosphate acetyltransferase
SDEG_RS04415	COG4221	oxidoreductase activity
SDEG_RS04430	COG1174	glycine betaine transport
SDEG_RS04445	COG2233	PERMEase
SDEG_RS04470	COG2890	protein-(glutamine-N5) methyltransferase activity
SDEG_RS04475	COG0009	L-threonylcarbamoyladenylate synthase
SDEG_RS04500	COG1132	(ABC) transporter
SDEG_RS04505	COG1132	(ABC) transporter
SDEG_RS04515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SDEG_RS04530	COG3764	Sortase (surface protein transpeptidase)
SDEG_RS04535	COG0346	lactoylglutathione lyase activity
SDEG_RS04550	COG0803	Belongs to the bacterial solute-binding protein 9 family
SDEG_RS04585	COG1136	(ABC) transporter
SDEG_RS04590	COG0577	efflux transmembrane transporter activity
SDEG_RS04595	COG0745	RESPONSE REGULATOR receiver
SDEG_RS04600	COG2205	protein histidine kinase activity
SDEG_RS04605	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDEG_RS04605	COG3942	CHAP domain
SDEG_RS04630	COG0803	Belongs to the bacterial solute-binding protein 9 family
SDEG_RS04650	COG1122	ATPase activity
SDEG_RS04660	COG0601	transmembrane transport
SDEG_RS04725	COG2188	Transcriptional regulator
SDEG_RS04735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SDEG_RS04755	COG0673	inositol 2-dehydrogenase activity
SDEG_RS04765	COG5002	protein histidine kinase activity
SDEG_RS04770	COG0662	Cupin 2, conserved barrel domain protein
SDEG_RS04805	COG5002	protein histidine kinase activity
SDEG_RS04810	COG0745	RESPONSE REGULATOR receiver
SDEG_RS04815	COG0577	efflux transmembrane transporter activity
SDEG_RS04820	COG1136	(ABC) transporter
SDEG_RS04835	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SDEG_RS04875	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SDEG_RS04880	COG0511	ligase activity, forming carbon-carbon bonds
SDEG_RS04890	COG2851	Citrate transporter
SDEG_RS04910	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SDEG_RS04915	COG0511	ligase activity, forming carbon-carbon bonds
SDEG_RS04965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SDEG_RS04970	COG0758	DNA mediated transformation
SDEG_RS04990	COG1396	sequence-specific DNA binding
SDEG_RS05000	COG1272	protein, Hemolysin III
SDEG_RS05020	COG0488	(ABC) transporter
SDEG_RS05040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SDEG_RS05045	COG1328	CTP reductase activity
SDEG_RS05045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SDEG_RS05050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SDEG_RS05055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SDEG_RS05115	COG0095	Lipoate-protein ligase
SDEG_RS05125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SDEG_RS05130	COG4684	Psort location CytoplasmicMembrane, score
SDEG_RS05135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SDEG_RS05140	COG1079	Belongs to the binding-protein-dependent transport system permease family
SDEG_RS05145	COG4603	Belongs to the binding-protein-dependent transport system permease family
SDEG_RS05150	COG3845	ABC transporter
SDEG_RS05155	COG1744	ABC transporter substrate-binding protein PnrA-like
SDEG_RS05170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SDEG_RS05175	COG2813	Specifically methylates the guanine in position
SDEG_RS05190	COG5002	protein histidine kinase activity
SDEG_RS05195	COG0745	RESPONSE REGULATOR receiver
SDEG_RS05205	COG0704	Plays a role in the regulation of phosphate uptake
SDEG_RS05220	COG0581	inorganic phosphate transmembrane transporter activity
SDEG_RS05225	COG0573	inorganic phosphate transmembrane transporter activity
SDEG_RS05235	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SDEG_RS05235	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SDEG_RS05240	COG0483	inositol monophosphate 1-phosphatase activity
SDEG_RS05255	COG0196	riboflavin kinase activity
SDEG_RS05290	COG1136	(ABC) transporter
SDEG_RS05290	COG4591	ABC-type transport system involved in lipoprotein release permease component
SDEG_RS05330	COG2261	transglycosylase associated protein
SDEG_RS05340	COG1115	amino acid carrier protein
SDEG_RS05345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SDEG_RS05355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDEG_RS05360	COG1126	abc transporter atp-binding protein
SDEG_RS05365	COG0765	amino acid transport
SDEG_RS05370	COG2824	Alkylphosphonate utilization operon protein PhnA
SDEG_RS05385	COG0469	pyruvate kinase activity
SDEG_RS05400	COG1725	Transcriptional regulator
SDEG_RS05405	COG1131	(ABC) transporter
SDEG_RS05415	COG0398	Pfam SNARE associated Golgi protein
SDEG_RS05440	COG0860	N-Acetylmuramoyl-L-alanine amidase
SDEG_RS05440	COG1388	LysM domain
SDEG_RS05450	COG4824	toxin secretion phage lysis holin
SDEG_RS05630	COG3723	Recombinational DNA repair protein, rece pathway
SDEG_RS05730	COG0539	negative regulation of cytoplasmic translation
SDEG_RS05750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SDEG_RS05770	COG0187	DNA topoisomerase II activity
SDEG_RS05790	COG0765	amino acid transport
SDEG_RS05795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDEG_RS05805	COG2801	Transposase and inactivated derivatives
SDEG_RS05850	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SDEG_RS05875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDEG_RS05885	COG0028	Belongs to the TPP enzyme family
SDEG_RS05890	COG0028	Belongs to the TPP enzyme family
SDEG_RS05915	COG1012	belongs to the aldehyde dehydrogenase family
SDEG_RS05920	COG1011	Hydrolase
SDEG_RS05930	COG0701	Predicted permease
SDEG_RS05955	COG2207	Transcriptional regulator
SDEG_RS05955	COG4753	response regulator
SDEG_RS05960	COG2972	Histidine kinase
SDEG_RS05965	COG3716	PTS system mannose fructose sorbose family IID component
SDEG_RS05970	COG3715	PTS system
SDEG_RS06005	COG1418	mRNA catabolic process
SDEG_RS06030	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SDEG_RS06035	COG1518	maintenance of DNA repeat elements
SDEG_RS06050	COG0647	UMP catabolic process
SDEG_RS06060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SDEG_RS06080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SDEG_RS06085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SDEG_RS06090	COG3442	glutamine amidotransferase
SDEG_RS06095	COG0095	Lipoate-protein ligase
SDEG_RS06105	COG1695	Transcriptional regulator
SDEG_RS06120	COG0508	dehydrogenase complex catalyzes the overall conversion of
SDEG_RS06125	COG0022	dehydrogenase e1 component
SDEG_RS06125	COG0508	dehydrogenase complex catalyzes the overall conversion of
SDEG_RS06130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SDEG_RS06135	COG0488	(ABC) transporter
SDEG_RS06155	COG1122	ATPase activity
SDEG_RS06185	COG3700	Belongs to the class B bacterial acid phosphatase family
SDEG_RS06205	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SDEG_RS06210	COG0457	Tetratricopeptide repeat
SDEG_RS06215	COG0628	permease
SDEG_RS06220	COG1051	belongs to the nudix hydrolase family
SDEG_RS06235	COG1088	dTDP-glucose 4,6-dehydratase activity
SDEG_RS06245	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SDEG_RS06250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SDEG_RS06265	COG2384	SAM-dependent methyltransferase
SDEG_RS06270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SDEG_RS06285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SDEG_RS06285	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SDEG_RS06290	COG0300	oxidoreductase activity
SDEG_RS06305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SDEG_RS06330	COG1054	Belongs to the UPF0176 family
SDEG_RS06340	COG0431	NADPH-dependent FMN reductase
SDEG_RS06345	COG0058	SHG alpha-glucan phosphorylase activity
SDEG_RS06350	COG1640	4-alpha-glucanotransferase
SDEG_RS06355	COG1609	Transcriptional regulator
SDEG_RS06365	COG2182	Extracellular solute-binding protein
SDEG_RS06375	COG3833	ABC-type maltose transport systems, permease component
SDEG_RS06390	COG3833	ABC-type maltose transport systems, permease component
SDEG_RS06400	COG0366	Alpha amylase catalytic
SDEG_RS06405	COG2182	Extracellular solute-binding protein
SDEG_RS06410	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SDEG_RS06420	COG1696	Membrane protein involved in D-alanine export
SDEG_RS06435	COG0556	nucleotide-excision repair
SDEG_RS06440	COG0765	amino acid transport
SDEG_RS06445	COG1126	abc transporter atp-binding protein
SDEG_RS06465	COG2309	aminopeptidase activity
SDEG_RS06475	COG1187	pseudouridine synthase activity
SDEG_RS06485	COG2814	Major facilitator Superfamily
SDEG_RS06495	COG0390	transport system, permease component
SDEG_RS06500	COG4619	ABC transporter
SDEG_RS06515	COG1464	Belongs to the NlpA lipoprotein family
SDEG_RS06530	COG0488	(ABC) transporter
SDEG_RS06535	COG0488	(ABC) transporter
SDEG_RS06580	COG3620	sequence-specific DNA binding
SDEG_RS06615	COG1484	DNA-dependent DNA replication
SDEG_RS06660	COG4109	DRTGG domain
SDEG_RS06685	COG1028	Short-chain dehydrogenase reductase Sdr
SDEG_RS06690	COG1312	Catalyzes the dehydration of D-mannonate
SDEG_RS06700	COG0800	Aldolase
SDEG_RS06705	COG2186	Transcriptional regulator
SDEG_RS06710	COG3250	beta-galactosidase activity
SDEG_RS06720	COG2211	Major facilitator Superfamily
SDEG_RS06740	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SDEG_RS06740	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SDEG_RS06745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SDEG_RS06750	COG1956	GAF domain-containing protein
SDEG_RS06770	COG0513	Belongs to the DEAD box helicase family
SDEG_RS06780	COG2801	Transposase and inactivated derivatives
SDEG_RS06785	COG2801	Transposase and inactivated derivatives
SDEG_RS06790	COG0561	phosphatase activity
SDEG_RS06800	COG2723	6-phospho-beta-galactosidase activity
SDEG_RS06810	COG0406	alpha-ribazole phosphatase activity
SDEG_RS06835	COG0561	phosphatase activity
SDEG_RS06845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SDEG_RS06855	COG1447	Phosphotransferase system cellobiose-specific component IIA
SDEG_RS06860	COG3711	transcriptional antiterminator
SDEG_RS06860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDEG_RS06885	COG3328	transposase activity
SDEG_RS06890	COG4095	Psort location CytoplasmicMembrane, score
SDEG_RS06895	COG2723	6-phospho-beta-galactosidase activity
SDEG_RS06900	COG1744	ABC transporter substrate-binding protein PnrA-like
SDEG_RS06925	COG4977	sequence-specific DNA binding
SDEG_RS06925	COG1917	Cupin 2, conserved barrel domain protein
SDEG_RS06930	COG1263	PTS System
SDEG_RS06930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDEG_RS06930	COG2190	(PTS) system
SDEG_RS06935	COG3711	transcriptional antiterminator
SDEG_RS06945	COG2801	Transposase and inactivated derivatives
SDEG_RS06950	COG0726	polysaccharide deacetylase
SDEG_RS06970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SDEG_RS06975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SDEG_RS06980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SDEG_RS07000	COG1476	TRANSCRIPTIONal
SDEG_RS07025	COG4122	O-methyltransferase activity
SDEG_RS07030	COG2223	nitrite transmembrane transporter activity
SDEG_RS07045	COG0431	NADPH-dependent FMN reductase
SDEG_RS07070	COG1187	pseudouridine synthase activity
SDEG_RS07105	COG2333	competence protein COMEC
SDEG_RS07105	COG0658	competence protein
SDEG_RS07110	COG1555	photosystem II stabilization
SDEG_RS07110	COG1596	polysaccharide export
SDEG_RS07115	COG0204	Acyl-transferase
SDEG_RS07120	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SDEG_RS07135	COG0513	Belongs to the DEAD box helicase family
SDEG_RS07140	COG1464	Belongs to the NlpA lipoprotein family
SDEG_RS07150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SDEG_RS07170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SDEG_RS07185	COG0768	penicillin binding
SDEG_RS07190	COG2116	formate transmembrane transporter activity
SDEG_RS07200	COG1827	regulation of RNA biosynthetic process
SDEG_RS07220	COG2217	Heavy metal translocating P-type atpase
SDEG_RS07245	COG2755	lipolytic protein G-D-S-L family
SDEG_RS07260	COG0497	DNA recombination
SDEG_RS07265	COG1438	arginine binding
SDEG_RS07270	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SDEG_RS07290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SDEG_RS07300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SDEG_RS07305	COG0415	Belongs to the DNA photolyase family
SDEG_RS07330	COG0765	amino acid transport
SDEG_RS07335	COG4703	Protein of unknown function (DUF1797)
SDEG_RS07340	COG0542	response to heat
SDEG_RS07345	COG1051	belongs to the nudix hydrolase family
SDEG_RS07360	COG3599	regulation of cell shape
SDEG_RS07380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SDEG_RS07390	COG0849	cell division
SDEG_RS07425	COG1217	gtp-binding protein TYPA
SDEG_RS07430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SDEG_RS07435	COG1940	carbohydrate kinase activity
SDEG_RS07445	COG0783	Belongs to the Dps family
SDEG_RS07455	COG2197	response regulator
SDEG_RS07460	COG4585	Histidine kinase
SDEG_RS07465	COG0842	Transport permease protein
SDEG_RS07470	COG1131	(ABC) transporter
SDEG_RS07475	COG1132	(ABC) transporter
SDEG_RS07490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SDEG_RS07495	COG4470	Protein conserved in bacteria
SDEG_RS07510	COG1879	ABC-type sugar transport system periplasmic component
SDEG_RS07520	COG1869	D-ribose catabolic process
SDEG_RS07525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDEG_RS07530	COG1609	Transcriptional regulator
SDEG_RS07535	COG3480	Lon protease (S16) C-terminal proteolytic domain
SDEG_RS07545	COG0742	ribosomal rna small subunit methyltransferase
SDEG_RS07555	COG0549	Belongs to the carbamate kinase family
SDEG_RS07565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDEG_RS07570	COG1288	antiporter activity
SDEG_RS07580	COG0454	-acetyltransferase
SDEG_RS07585	COG2235	arginine
SDEG_RS07590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SDEG_RS07610	COG2972	Histidine kinase
SDEG_RS07625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDEG_RS07630	COG0785	Cytochrome C biogenesis protein
SDEG_RS07640	COG0673	inositol 2-dehydrogenase activity
SDEG_RS07665	COG0346	lactoylglutathione lyase activity
SDEG_RS07685	COG0534	Mate efflux family protein
SDEG_RS07695	COG1605	Chorismate mutase
SDEG_RS07695	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SDEG_RS07725	COG3250	beta-galactosidase activity
SDEG_RS07730	COG2207	Transcriptional regulator
SDEG_RS07730	COG4753	response regulator
SDEG_RS07735	COG2972	Histidine kinase
SDEG_RS07745	COG1653	transport
SDEG_RS07750	COG0395	ABC-type sugar transport system, permease component
SDEG_RS07755	COG1175	transmembrane transport
SDEG_RS07760	COG1940	carbohydrate kinase activity
SDEG_RS07775	COG2723	6-phospho-beta-galactosidase activity
SDEG_RS07780	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SDEG_RS07795	COG0383	alpha-mannosidase activity
SDEG_RS07810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SDEG_RS07820	COG2070	2-Nitropropane dioxygenase
SDEG_RS07825	COG0183	Belongs to the thiolase family
SDEG_RS07830	COG1250	3-hydroxyacyl-CoA dehydrogenase
SDEG_RS07830	COG1024	Enoyl-CoA hydratase
SDEG_RS07995	COG1783	phage Terminase large subunit
SDEG_RS08215	COG1040	competence protein
SDEG_RS08220	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SDEG_RS08225	COG1739	Uncharacterized protein family UPF0029
SDEG_RS08235	COG1098	S1 RNA binding domain
SDEG_RS08245	COG2197	response regulator
SDEG_RS08250	COG4585	Histidine kinase
SDEG_RS08260	COG2815	serine threonine protein kinase
SDEG_RS08260	COG0515	serine threonine protein kinase
SDEG_RS08270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SDEG_RS08270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SDEG_RS08280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SDEG_RS08300	COG0583	DNA-binding transcription factor activity
SDEG_RS08305	COG0183	Belongs to the thiolase family
SDEG_RS08310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SDEG_RS08320	COG1028	Short-chain dehydrogenase reductase Sdr
SDEG_RS08340	COG0116	Belongs to the methyltransferase superfamily
SDEG_RS08360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDEG_RS08365	COG3579	cysteine-type endopeptidase activity
SDEG_RS08375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SDEG_RS08380	COG1113	amino acid transport
SDEG_RS08385	COG0492	ferredoxin-NADP+ reductase activity
SDEG_RS08395	COG1126	abc transporter atp-binding protein
SDEG_RS08400	COG0765	amino acid transport
SDEG_RS08410	COG0513	Belongs to the DEAD box helicase family
SDEG_RS08420	COG0768	penicillin binding
SDEG_RS08450	COG1131	(ABC) transporter
SDEG_RS08475	COG0446	pyridine nucleotide-disulphide oxidoreductase
SDEG_RS08480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDEG_RS08515	COG1755	Isoprenylcysteine carboxyl methyltransferase
SDEG_RS08520	COG0656	L-ascorbic acid biosynthetic process
SDEG_RS08530	COG1283	sodium-dependent phosphate transmembrane transporter activity
SDEG_RS08550	COG0561	phosphatase activity
SDEG_RS08555	COG2860	membrane
SDEG_RS08590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDEG_RS08605	COG2217	Heavy metal translocating P-type atpase
SDEG_RS08640	COG4509	Sortase family
SDEG_RS08700	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SDEG_RS08705	COG0195	Participates in both transcription termination and antitermination
SDEG_RS08730	COG4473	ABC transporter
SDEG_RS08735	COG1131	(ABC) transporter
SDEG_RS08740	COG0537	adenosine 5'-monophosphoramidase activity
SDEG_RS08750	COG1316	TRANSCRIPTIONal
SDEG_RS08755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SDEG_RS08760	COG0802	atpase or kinase
SDEG_RS08765	COG2252	PERMEase
SDEG_RS08770	COG0561	phosphatase activity
SDEG_RS08780	COG3715	PTS system
SDEG_RS08785	COG3716	PTS system mannose fructose sorbose family IID component
SDEG_RS08815	COG0439	Biotin carboxylase
SDEG_RS08830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDEG_RS08835	COG1028	Short-chain dehydrogenase reductase Sdr
SDEG_RS08840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SDEG_RS08845	COG2070	2-Nitropropane dioxygenase
SDEG_RS08865	COG1024	Enoyl-CoA hydratase
SDEG_RS08870	COG0484	heat shock protein binding
SDEG_RS08890	COG1420	regulation of RNA biosynthetic process
SDEG_RS08905	COG0588	phosphoglycerate mutase activity
SDEG_RS08910	COG2261	transglycosylase associated protein
SDEG_RS08915	COG0697	spore germination
SDEG_RS08925	COG5433	transposase activity
SDEG_RS08945	COG0574	Belongs to the PEP-utilizing enzyme family
SDEG_RS08945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SDEG_RS08950	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SDEG_RS08955	COG0517	IMP dehydrogenase activity
SDEG_RS08965	COG0446	pyridine nucleotide-disulphide oxidoreductase
SDEG_RS08975	COG1937	Protein conserved in bacteria
SDEG_RS08980	COG1335	isochorismatase
SDEG_RS08990	COG0436	Aminotransferase
SDEG_RS09000	COG0561	phosphatase activity
SDEG_RS09005	COG0252	asparaginase activity
SDEG_RS09010	COG4989	oxidoreductase activity
SDEG_RS09015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SDEG_RS09020	COG1129	ABC transporter
SDEG_RS09035	COG1132	(ABC) transporter
SDEG_RS09040	COG4988	ABC transporter
SDEG_RS09045	COG1120	ATPase activity
SDEG_RS09070	COG1388	LysM domain
SDEG_RS09070	COG3942	CHAP domain
SDEG_RS09090	COG1482	cell wall glycoprotein biosynthetic process
SDEG_RS09095	COG1940	carbohydrate kinase activity
SDEG_RS09100	COG1263	PTS System
SDEG_RS09100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDEG_RS09100	COG2190	(PTS) system
SDEG_RS09105	COG1621	beta-fructofuranosidase activity
SDEG_RS09110	COG1609	Transcriptional regulator
SDEG_RS09130	COG2131	deaminase
SDEG_RS09135	COG0006	proline dipeptidase activity
SDEG_RS09175	COG1194	a g-specific adenine glycosylase
SDEG_RS09180	COG3118	belongs to the thioredoxin family
SDEG_RS09185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SDEG_RS09210	COG0681	Belongs to the peptidase S26 family
SDEG_RS09215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SDEG_RS09230	COG1882	Formate acetyltransferase
SDEG_RS09235	COG2153	protein acetylation
SDEG_RS09245	COG1653	transport
SDEG_RS09255	COG0395	ABC-type sugar transport system, permease component
SDEG_RS09260	COG4209	transmembrane transport
SDEG_RS09270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SDEG_RS09285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SDEG_RS09315	COG0789	Transcriptional regulator
SDEG_RS09330	COG2081	HI0933 family
SDEG_RS09355	COG1214	PFAM Peptidase M22, glycoprotease
SDEG_RS09360	COG5503	Protein of unknown function (DUF1447)
SDEG_RS09370	COG4608	Belongs to the ABC transporter superfamily
SDEG_RS09375	COG0444	Belongs to the ABC transporter superfamily
SDEG_RS09380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SDEG_RS09385	COG0601	transmembrane transport
SDEG_RS09390	COG4166	transmembrane transport
SDEG_RS09395	COG0174	glutamine synthetase
SDEG_RS09400	COG0789	Transcriptional regulator
SDEG_RS09420	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SDEG_RS09450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SDEG_RS09465	COG1564	THIamine pyrophosphokinase
SDEG_RS09490	COG0084	hydrolase, TatD family'
SDEG_RS09495	COG1335	isochorismatase
SDEG_RS09510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SDEG_RS09525	COG0395	ABC-type sugar transport system, permease component
SDEG_RS09530	COG1175	transmembrane transport
SDEG_RS09550	COG1847	R3H domain protein
SDEG_RS09615	COG0756	dUTP diphosphatase activity
SDEG_RS09625	COG1132	(ABC) transporter
SDEG_RS09630	COG1132	(ABC) transporter
SDEG_RS09645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SDEG_RS09655	COG0705	Rhomboid family
SDEG_RS09655	COG0457	Tetratricopeptide repeat
SDEG_RS09660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SDEG_RS09690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SDEG_RS09715	COG1234	tRNA 3'-trailer cleavage
SDEG_RS09720	COG1268	BioY protein
SDEG_RS09740	COG1832	CoA-binding protein
SDEG_RS09745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDEG_RS09745	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDEG_RS09755	COG4175	Glycine betaine
SDEG_RS09755	COG3448	diguanylate cyclase activity
SDEG_RS09760	COG1597	lipid kinase activity
SDEG_RS09785	COG3623	hexulose-6-phosphate isomerase
SDEG_RS09795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDEG_RS09840	COG1132	(ABC) transporter
SDEG_RS09845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SDEG_RS09885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDEG_RS09900	COG0564	pseudouridine synthase activity
SDEG_RS09915	COG1051	belongs to the nudix hydrolase family
SDEG_RS09930	COG0542	response to heat
SDEG_RS09935	COG4463	regulation of RNA biosynthetic process
SDEG_RS09965	COG0450	alkyl hydroperoxide reductase
SDEG_RS09980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SDEG_RS09990	COG3404	Formiminotransferase-cyclodeaminase
SDEG_RS10005	COG0531	amino acid
SDEG_RS10035	COG3590	peptidase
SDEG_RS10040	COG0366	Alpha amylase catalytic
SDEG_RS10045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SDEG_RS10045	COG1263	PTS System
SDEG_RS10050	COG2188	Transcriptional regulator
SDEG_RS10070	COG0602	queuosine metabolic process
SDEG_RS10105	COG4472	Bacterial protein of unknown function (DUF965)
SDEG_RS10110	COG1393	Belongs to the ArsC family
SDEG_RS10130	COG0519	Catalyzes the synthesis of GMP from XMP
SDEG_RS10140	COG2814	Major facilitator Superfamily
SDEG_RS10170	COG0488	(ABC) transporter
SDEG_RS10175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDEG_RS10180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDEG_RS10185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDEG_RS10265	COG1511	domain protein
SDEG_RS10395	COG0582	viral genome integration into host DNA
SDEG_RS10415	COG0305	Participates in initiation and elongation during chromosome replication
SDEG_RS10440	COG2095	MarC family integral membrane protein
SDEG_RS10450	COG1760	l-serine dehydratase
SDEG_RS10455	COG1760	l-serine dehydratase
SDEG_RS10465	COG0741	lytic transglycosylase activity
SDEG_RS10485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SDEG_RS10495	COG0612	Peptidase, M16
SDEG_RS10520	COG0516	GMP reductase activity
SDEG_RS10520	COG0517	IMP dehydrogenase activity
SDEG_RS10530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SDEG_RS10535	COG0488	(ABC) transporter
SDEG_RS10570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain