locus-tag	class	description
GGS_RS00010	COG0592	DNA-directed DNA polymerase activity
GGS_RS00030	COG0012	GTP binding
GGS_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GGS_RS00045	COG2244	polysaccharide biosynthetic process
GGS_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GGS_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GGS_RS00080	COG0531	amino acid
GGS_RS00190	COG3942	CHAP domain
GGS_RS00210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GGS_RS00215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GGS_RS00220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GGS_RS00230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GGS_RS00235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GGS_RS00250	COG3942	CHAP domain
GGS_RS00255	COG0151	Belongs to the GarS family
GGS_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GGS_RS00275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GGS_RS00285	COG5433	transposase activity
GGS_RS00295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGS_RS00310	COG1012	belongs to the aldehyde dehydrogenase family
GGS_RS00310	COG1454	alcohol dehydrogenase
GGS_RS00315	COG1064	alcohol dehydrogenase
GGS_RS00320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GGS_RS00335	COG0051	transcription antitermination factor activity, RNA binding
GGS_RS00435	COG0200	Binds to the 23S rRNA
GGS_RS00440	COG0201	protein transport
GGS_RS00455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GGS_RS00565	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GGS_RS00575	COG1252	NADH dehydrogenase
GGS_RS00580	COG1271	oxidase subunit
GGS_RS00585	COG1294	oxidase, subunit
GGS_RS00590	COG4988	ABC transporter
GGS_RS00595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GGS_RS00600	COG0142	geranyltranstransferase activity
GGS_RS00615	COG1121	(ABC) transporter
GGS_RS00620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GGS_RS00630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GGS_RS00630	COG4499	WXG100 protein secretion system (Wss), protein YukC
GGS_RS00650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGS_RS00655	COG1459	type II secretion system
GGS_RS00660	COG4537	Required for transformation and DNA binding
GGS_RS00700	COG1266	CAAX protease self-immunity
GGS_RS00710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GGS_RS00725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGS_RS00730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGS_RS00755	COG4120	Belongs to the binding-protein-dependent transport system permease family
GGS_RS00770	COG1428	Deoxynucleoside kinase
GGS_RS00775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGS_RS00840	COG0251	oxidation-reduction process
GGS_RS00865	COG1744	ABC transporter substrate-binding protein PnrA-like
GGS_RS00870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGS_RS00875	COG1349	DNA-binding transcription factor activity
GGS_RS00880	COG2390	Transcriptional regulator
GGS_RS00885	COG1447	Phosphotransferase system cellobiose-specific component IIA
GGS_RS00890	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GGS_RS00895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GGS_RS00900	COG1882	Formate acetyltransferase
GGS_RS00945	COG3655	Transcriptional regulator
GGS_RS00960	COG0488	(ABC) transporter
GGS_RS01010	COG1132	(ABC) transporter
GGS_RS01035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GGS_RS01040	COG0512	Glutamine amidotransferase of anthranilate synthase
GGS_RS01045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GGS_RS01060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GGS_RS01065	COG1609	Transcriptional regulator
GGS_RS01070	COG2190	(PTS) system
GGS_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGS_RS01070	COG1263	PTS System
GGS_RS01085	COG1363	Peptidase, m42
GGS_RS01135	COG3842	ATPase activity
GGS_RS01145	COG1523	belongs to the glycosyl hydrolase 13 family
GGS_RS01160	COG1862	Preprotein translocase
GGS_RS01170	COG4589	Belongs to the CDS family
GGS_RS01195	COG1846	Transcriptional regulator
GGS_RS01200	COG0431	NADPH-dependent FMN reductase
GGS_RS01225	COG3711	transcriptional antiterminator
GGS_RS01240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GGS_RS01255	COG1045	serine acetyltransferase
GGS_RS01270	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GGS_RS01290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGS_RS01310	COG1476	TRANSCRIPTIONal
GGS_RS01320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GGS_RS01340	COG1705	Flagellar rod assembly protein muramidase FlgJ
GGS_RS01340	COG3942	CHAP domain
GGS_RS01355	COG0433	COG0433 Predicted ATPase
GGS_RS01390	COG1674	ftsk spoiiie
GGS_RS01405	COG5433	transposase activity
GGS_RS01410	COG3620	sequence-specific DNA binding
GGS_RS01425	COG3620	sequence-specific DNA binding
GGS_RS01430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GGS_RS01465	COG2217	Heavy metal translocating P-type atpase
GGS_RS01550	COG3775	system Galactitol-specific IIC component
GGS_RS01555	COG3414	Phosphotransferase system galactitol-specific IIB component
GGS_RS01575	COG0561	phosphatase activity
GGS_RS01630	COG0351	phosphomethylpyrimidine kinase
GGS_RS01635	COG4720	Psort location CytoplasmicMembrane, score
GGS_RS01645	COG0668	transmembrane transport
GGS_RS01655	COG0366	Alpha amylase catalytic
GGS_RS01665	COG3343	RNA polymerase activity
GGS_RS01680	COG3279	Response regulator of the LytR AlgR family
GGS_RS01690	COG1346	cytolysis
GGS_RS01735	COG0765	amino acid transport
GGS_RS01755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGS_RS01765	COG0719	Fe-S assembly protein
GGS_RS01770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GGS_RS01790	COG1686	Belongs to the peptidase S11 family
GGS_RS01795	COG1686	Belongs to the peptidase S11 family
GGS_RS01800	COG4166	transmembrane transport
GGS_RS01805	COG0601	transmembrane transport
GGS_RS01810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGS_RS01815	COG0444	Belongs to the ABC transporter superfamily
GGS_RS01870	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GGS_RS01875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GGS_RS01880	COG1534	Rna-binding protein
GGS_RS01890	COG1713	HD superfamily hydrolase involved in NAD metabolism
GGS_RS01900	COG0799	negative regulation of ribosome biogenesis
GGS_RS01905	COG2226	methyltransferase
GGS_RS01915	COG0789	Transcriptional regulator
GGS_RS01935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GGS_RS01945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGS_RS01955	COG1464	Belongs to the NlpA lipoprotein family
GGS_RS01960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGS_RS01975	COG1114	Component of the transport system for branched-chain amino acids
GGS_RS01985	COG0569	domain protein
GGS_RS01990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGS_RS02000	COG1704	LemA family
GGS_RS02015	COG0745	RESPONSE REGULATOR receiver
GGS_RS02020	COG5002	protein histidine kinase activity
GGS_RS02025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GGS_RS02035	COG1484	DNA-dependent DNA replication
GGS_RS02045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GGS_RS02065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GGS_RS02085	COG1254	Belongs to the acylphosphatase family
GGS_RS02090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGS_RS02125	COG4175	Glycine betaine
GGS_RS02145	COG1187	pseudouridine synthase activity
GGS_RS02165	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GGS_RS02170	COG0671	phosphoesterase, PA-phosphatase related
GGS_RS02175	COG1242	4 iron, 4 sulfur cluster binding
GGS_RS02180	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GGS_RS02185	COG1253	flavin adenine dinucleotide binding
GGS_RS02190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGS_RS02205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGS_RS02210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGS_RS02215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGS_RS02220	COG1120	ATPase activity
GGS_RS02230	COG2244	polysaccharide biosynthetic process
GGS_RS02265	COG0559	Belongs to the binding-protein-dependent transport system permease family
GGS_RS02275	COG0411	ABC transporter
GGS_RS02285	COG0517	IMP dehydrogenase activity
GGS_RS02295	COG0470	DNA polymerase III
GGS_RS02300	COG1774	PSP1 C-terminal conserved region
GGS_RS02325	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GGS_RS02340	COG1393	Belongs to the ArsC family
GGS_RS02355	COG1609	Transcriptional regulator
GGS_RS02360	COG0561	phosphatase activity
GGS_RS02365	COG0708	Exodeoxyribonuclease III
GGS_RS02375	COG1620	l-lactate permease
GGS_RS02380	COG1304	FMN binding
GGS_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
GGS_RS02450	COG0673	inositol 2-dehydrogenase activity
GGS_RS02465	COG0494	nUDIX hydrolase
GGS_RS02475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GGS_RS02500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGS_RS02565	COG1702	phosphate starvation-inducible protein PhoH
GGS_RS02570	COG1573	uracil-dna glycosylase
GGS_RS02605	COG3328	transposase activity
GGS_RS02610	COG3328	transposase activity
GGS_RS02650	COG1396	sequence-specific DNA binding
GGS_RS02665	COG1131	(ABC) transporter
GGS_RS02675	COG0433	COG0433 Predicted ATPase
GGS_RS02685	COG2814	Major facilitator Superfamily
GGS_RS02695	COG0557	exoribonuclease II activity
GGS_RS02700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GGS_RS02710	COG2801	Transposase and inactivated derivatives
GGS_RS02720	COG0463	Glycosyl transferase, family 2
GGS_RS02730	COG0346	lactoylglutathione lyase activity
GGS_RS02735	COG0778	Nitroreductase
GGS_RS02740	COG0006	proline dipeptidase activity
GGS_RS02745	COG1609	Transcriptional regulator
GGS_RS02760	COG0438	transferase activity, transferring glycosyl groups
GGS_RS02770	COG4555	ABC transporter
GGS_RS02790	COG2376	Dihydroxyacetone kinase
GGS_RS02800	COG2376	Dihydroxyacetone kinase
GGS_RS02805	COG1461	Dihydroxyacetone kinase
GGS_RS02810	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GGS_RS02815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GGS_RS02825	COG0183	Belongs to the thiolase family
GGS_RS02830	COG0318	PFAM AMP-dependent synthetase and ligase
GGS_RS02840	COG0765	amino acid transport
GGS_RS02845	COG0765	amino acid transport
GGS_RS02850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGS_RS02860	COG0745	RESPONSE REGULATOR receiver
GGS_RS02870	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GGS_RS02880	COG1196	nuclear chromosome segregation
GGS_RS02895	COG5433	transposase activity
GGS_RS02900	COG0561	phosphatase activity
GGS_RS02905	COG0561	phosphatase activity
GGS_RS02910	COG0552	protein localization to endoplasmic reticulum
GGS_RS02915	COG0477	Major facilitator Superfamily
GGS_RS02920	COG3711	transcriptional antiterminator
GGS_RS02925	COG1263	PTS System
GGS_RS02925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGS_RS02925	COG2190	(PTS) system
GGS_RS02935	COG3689	TIGRFAM TIGR03943 family protein
GGS_RS02940	COG0701	Predicted permease
GGS_RS02960	COG0745	RESPONSE REGULATOR receiver
GGS_RS02965	COG5002	protein histidine kinase activity
GGS_RS02970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GGS_RS02975	COG0573	inorganic phosphate transmembrane transporter activity
GGS_RS02985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGS_RS02990	COG0704	Plays a role in the regulation of phosphate uptake
GGS_RS03000	COG2183	response to ionizing radiation
GGS_RS03045	COG0826	peptidase U32
GGS_RS03050	COG4443	Transcriptional Coactivator p15 (PC4)
GGS_RS03065	COG0004	ammonium transporteR
GGS_RS03090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGS_RS03125	COG0386	Belongs to the glutathione peroxidase family
GGS_RS03130	COG1164	Oligoendopeptidase f
GGS_RS03140	COG0772	Belongs to the SEDS family
GGS_RS03145	COG1191	sigma factor activity
GGS_RS03190	COG2801	Transposase and inactivated derivatives
GGS_RS03230	COG1078	dGTPase activity
GGS_RS03250	COG1609	Transcriptional regulator
GGS_RS03260	COG3716	PTS system mannose fructose sorbose family IID component
GGS_RS03265	COG3715	PTS system
GGS_RS03270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGS_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
GGS_RS03305	COG5492	domain, Protein
GGS_RS03340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGS_RS03345	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GGS_RS03350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GGS_RS03355	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GGS_RS03360	COG2884	Cell division ATP-binding protein ftsE
GGS_RS03365	COG2177	Part of the ABC transporter FtsEX involved in
GGS_RS03375	COG1199	ATP-dependent helicase activity
GGS_RS03375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GGS_RS03380	COG0436	Aminotransferase
GGS_RS03385	COG0017	Asparaginyl-tRNA synthetase
GGS_RS03420	COG2188	Transcriptional regulator
GGS_RS03450	COG3715	PTS system
GGS_RS03455	COG3716	PTS system mannose fructose sorbose family IID component
GGS_RS03475	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GGS_RS03480	COG2153	protein acetylation
GGS_RS03485	COG0625	glutathione transferase activity
GGS_RS03495	COG0716	FMN binding
GGS_RS03505	COG0038	chloride channel
GGS_RS03520	COG0772	Belongs to the SEDS family
GGS_RS03540	COG0560	Phosphoserine phosphatase
GGS_RS03580	COG1131	(ABC) transporter
GGS_RS03600	COG4708	membrane
GGS_RS03610	COG1597	lipid kinase activity
GGS_RS03615	COG1523	belongs to the glycosyl hydrolase 13 family
GGS_RS03620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GGS_RS03625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GGS_RS03720	COG0577	efflux transmembrane transporter activity
GGS_RS03730	COG2321	neutral zinc metallopeptidase
GGS_RS03745	COG0436	Aminotransferase
GGS_RS03760	COG1970	mechanosensitive ion channel activity
GGS_RS03765	COG0358	DNA primase activity
GGS_RS03770	COG2151	metal-sulfur cluster biosynthetic enzyme
GGS_RS03785	COG1216	Glycosyl transferase, family 2
GGS_RS03785	COG1442	glycosyl transferase family 8
GGS_RS03825	COG0463	Glycosyl transferase, family 2
GGS_RS03840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GGS_RS03890	COG1368	sulfuric ester hydrolase activity
GGS_RS03915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGS_RS03920	COG0285	dihydrofolate synthase activity
GGS_RS03930	COG1104	cysteine desulfurase activity
GGS_RS03960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GGS_RS03965	COG0583	DNA-binding transcription factor activity
GGS_RS03975	COG0564	pseudouridine synthase activity
GGS_RS04010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGS_RS04015	COG1136	(ABC) transporter
GGS_RS04020	COG0577	efflux transmembrane transporter activity
GGS_RS04030	COG0584	glycerophosphoryl diester phosphodiesterase
GGS_RS04040	COG1837	Belongs to the UPF0109 family
GGS_RS04095	COG1105	Belongs to the carbohydrate kinase PfkB family
GGS_RS04100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGS_RS04100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGS_RS04100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGS_RS04105	COG1388	LysM domain
GGS_RS04105	COG1705	Flagellar rod assembly protein muramidase FlgJ
GGS_RS04110	COG1388	LysM domain
GGS_RS04110	COG1705	Flagellar rod assembly protein muramidase FlgJ
GGS_RS04135	COG0488	(ABC) transporter
GGS_RS04145	COG1132	(ABC) transporter
GGS_RS04150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GGS_RS04155	COG0242	peptide deformylase activity
GGS_RS04160	COG0737	Belongs to the 5'-nucleotidase family
GGS_RS04170	COG0745	RESPONSE REGULATOR receiver
GGS_RS04225	COG3425	synthase
GGS_RS04235	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GGS_RS04290	COG1349	DNA-binding transcription factor activity
GGS_RS04300	COG0698	ribose 5-phosphate isomerase
GGS_RS04305	COG1105	Belongs to the carbohydrate kinase PfkB family
GGS_RS04310	COG3684	Belongs to the aldolase LacD family
GGS_RS04315	COG3711	transcriptional antiterminator
GGS_RS04320	COG1447	Phosphotransferase system cellobiose-specific component IIA
GGS_RS04325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GGS_RS04325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GGS_RS04330	COG2723	6-phospho-beta-galactosidase activity
GGS_RS04345	COG1396	sequence-specific DNA binding
GGS_RS04360	COG1686	Belongs to the peptidase S11 family
GGS_RS04365	COG0726	polysaccharide deacetylase
GGS_RS04380	COG0285	dihydrofolate synthase activity
GGS_RS04385	COG0302	gtp cyclohydrolase
GGS_RS04415	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGS_RS04420	COG1177	transmembrane transport
GGS_RS04430	COG4565	transcriptional regulatory protein
GGS_RS04435	COG3290	protein histidine kinase activity
GGS_RS04440	COG3493	citrate carrier protein
GGS_RS04450	COG0038	chloride channel
GGS_RS04455	COG1917	Cupin 2, conserved barrel domain protein
GGS_RS04455	COG4977	sequence-specific DNA binding
GGS_RS04465	COG0628	permease
GGS_RS04475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GGS_RS04495	COG1104	cysteine desulfurase activity
GGS_RS04510	COG2357	RelA SpoT domain protein
GGS_RS04520	COG0564	pseudouridine synthase activity
GGS_RS04525	COG0280	phosphate acetyltransferase
GGS_RS04530	COG4221	oxidoreductase activity
GGS_RS04545	COG1174	glycine betaine transport
GGS_RS04560	COG2233	PERMEase
GGS_RS04585	COG2890	protein-(glutamine-N5) methyltransferase activity
GGS_RS04590	COG0009	L-threonylcarbamoyladenylate synthase
GGS_RS04615	COG1132	(ABC) transporter
GGS_RS04620	COG1132	(ABC) transporter
GGS_RS04630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GGS_RS04645	COG3764	Sortase (surface protein transpeptidase)
GGS_RS04650	COG0346	lactoylglutathione lyase activity
GGS_RS04670	COG0803	Belongs to the bacterial solute-binding protein 9 family
GGS_RS04705	COG1136	(ABC) transporter
GGS_RS04710	COG0577	efflux transmembrane transporter activity
GGS_RS04715	COG0745	RESPONSE REGULATOR receiver
GGS_RS04720	COG2205	protein histidine kinase activity
GGS_RS04725	COG1705	Flagellar rod assembly protein muramidase FlgJ
GGS_RS04725	COG3942	CHAP domain
GGS_RS04755	COG0803	Belongs to the bacterial solute-binding protein 9 family
GGS_RS04785	COG0601	transmembrane transport
GGS_RS04935	COG2188	Transcriptional regulator
GGS_RS04945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GGS_RS04965	COG0673	inositol 2-dehydrogenase activity
GGS_RS04990	COG4939	FMN-binding domain protein
GGS_RS04995	COG0142	geranyltranstransferase activity
GGS_RS05000	COG1252	NADH dehydrogenase
GGS_RS05010	COG5002	protein histidine kinase activity
GGS_RS05015	COG0745	RESPONSE REGULATOR receiver
GGS_RS05020	COG0577	efflux transmembrane transporter activity
GGS_RS05025	COG1136	(ABC) transporter
GGS_RS05040	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GGS_RS05085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGS_RS05090	COG0758	DNA mediated transformation
GGS_RS05100	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GGS_RS05110	COG1396	sequence-specific DNA binding
GGS_RS05120	COG1272	protein, Hemolysin III
GGS_RS05140	COG0488	(ABC) transporter
GGS_RS05175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GGS_RS05175	COG1328	CTP reductase activity
GGS_RS05180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGS_RS05185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGS_RS05245	COG0095	Lipoate-protein ligase
GGS_RS05255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GGS_RS05260	COG4684	Psort location CytoplasmicMembrane, score
GGS_RS05265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGS_RS05270	COG1079	Belongs to the binding-protein-dependent transport system permease family
GGS_RS05275	COG4603	Belongs to the binding-protein-dependent transport system permease family
GGS_RS05280	COG3845	ABC transporter
GGS_RS05285	COG1744	ABC transporter substrate-binding protein PnrA-like
GGS_RS05300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GGS_RS05305	COG2813	Specifically methylates the guanine in position
GGS_RS05320	COG5002	protein histidine kinase activity
GGS_RS05325	COG0745	RESPONSE REGULATOR receiver
GGS_RS05335	COG0704	Plays a role in the regulation of phosphate uptake
GGS_RS05350	COG0581	inorganic phosphate transmembrane transporter activity
GGS_RS05355	COG0573	inorganic phosphate transmembrane transporter activity
GGS_RS05365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGS_RS05365	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GGS_RS05370	COG0483	inositol monophosphate 1-phosphatase activity
GGS_RS05385	COG0196	riboflavin kinase activity
GGS_RS05415	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGS_RS05415	COG1136	(ABC) transporter
GGS_RS05465	COG1115	amino acid carrier protein
GGS_RS05470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GGS_RS05480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGS_RS05485	COG1126	abc transporter atp-binding protein
GGS_RS05490	COG0765	amino acid transport
GGS_RS05495	COG2824	Alkylphosphonate utilization operon protein PhnA
GGS_RS05510	COG0469	pyruvate kinase activity
GGS_RS05525	COG1725	Transcriptional regulator
GGS_RS05530	COG1131	(ABC) transporter
GGS_RS05540	COG0398	Pfam SNARE associated Golgi protein
GGS_RS05565	COG0539	negative regulation of cytoplasmic translation
GGS_RS05585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGS_RS05600	COG0187	DNA topoisomerase II activity
GGS_RS05620	COG0765	amino acid transport
GGS_RS05635	COG2801	Transposase and inactivated derivatives
GGS_RS05675	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GGS_RS05700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGS_RS05710	COG0028	Belongs to the TPP enzyme family
GGS_RS05715	COG0028	Belongs to the TPP enzyme family
GGS_RS05740	COG1012	belongs to the aldehyde dehydrogenase family
GGS_RS05745	COG1011	Hydrolase
GGS_RS05760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGS_RS05775	COG4753	response regulator
GGS_RS05775	COG2207	Transcriptional regulator
GGS_RS05780	COG2972	Histidine kinase
GGS_RS05785	COG3716	PTS system mannose fructose sorbose family IID component
GGS_RS05790	COG3715	PTS system
GGS_RS05825	COG1418	mRNA catabolic process
GGS_RS05850	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GGS_RS05855	COG1518	maintenance of DNA repeat elements
GGS_RS05870	COG0647	UMP catabolic process
GGS_RS05880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGS_RS05900	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GGS_RS05905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GGS_RS05910	COG3442	glutamine amidotransferase
GGS_RS05915	COG0095	Lipoate-protein ligase
GGS_RS05925	COG1695	Transcriptional regulator
GGS_RS05940	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGS_RS05945	COG0022	dehydrogenase e1 component
GGS_RS05945	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGS_RS05950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GGS_RS05955	COG0488	(ABC) transporter
GGS_RS05975	COG1122	ATPase activity
GGS_RS06005	COG3700	Belongs to the class B bacterial acid phosphatase family
GGS_RS06035	COG5433	transposase activity
GGS_RS06040	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GGS_RS06045	COG0457	Tetratricopeptide repeat
GGS_RS06055	COG1051	belongs to the nudix hydrolase family
GGS_RS06070	COG1088	dTDP-glucose 4,6-dehydratase activity
GGS_RS06080	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GGS_RS06085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGS_RS06100	COG2384	SAM-dependent methyltransferase
GGS_RS06105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GGS_RS06120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GGS_RS06120	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GGS_RS06125	COG0300	oxidoreductase activity
GGS_RS06140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GGS_RS06160	COG0572	uridine kinase
GGS_RS06165	COG1054	Belongs to the UPF0176 family
GGS_RS06175	COG0431	NADPH-dependent FMN reductase
GGS_RS06180	COG0058	SHG alpha-glucan phosphorylase activity
GGS_RS06185	COG1640	4-alpha-glucanotransferase
GGS_RS06190	COG1609	Transcriptional regulator
GGS_RS06200	COG2182	Extracellular solute-binding protein
GGS_RS06210	COG3833	ABC-type maltose transport systems, permease component
GGS_RS06225	COG3833	ABC-type maltose transport systems, permease component
GGS_RS06235	COG0366	Alpha amylase catalytic
GGS_RS06240	COG2182	Extracellular solute-binding protein
GGS_RS06245	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GGS_RS06255	COG1696	Membrane protein involved in D-alanine export
GGS_RS06275	COG0765	amino acid transport
GGS_RS06280	COG1126	abc transporter atp-binding protein
GGS_RS06285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GGS_RS06295	COG1447	Phosphotransferase system cellobiose-specific component IIA
GGS_RS06305	COG3711	transcriptional antiterminator
GGS_RS06305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGS_RS06315	COG2723	6-phospho-beta-galactosidase activity
GGS_RS06335	COG2309	aminopeptidase activity
GGS_RS06345	COG1187	pseudouridine synthase activity
GGS_RS06355	COG2814	Major facilitator Superfamily
GGS_RS06365	COG0390	transport system, permease component
GGS_RS06370	COG4619	ABC transporter
GGS_RS06385	COG1464	Belongs to the NlpA lipoprotein family
GGS_RS06435	COG0534	Mate efflux family protein
GGS_RS06440	COG1129	ABC transporter
GGS_RS06455	COG1132	(ABC) transporter
GGS_RS06460	COG1132	(ABC) transporter
GGS_RS06460	COG2375	cellular response to nickel ion
GGS_RS06465	COG1309	transcriptional regulator
GGS_RS06480	COG4581	dead DEAH box helicase
GGS_RS06520	COG0551	DNA topoisomerase type I activity
GGS_RS06520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGS_RS06620	COG1129	ABC transporter
GGS_RS06625	COG1132	(ABC) transporter
GGS_RS06630	COG1132	(ABC) transporter
GGS_RS06635	COG1309	transcriptional regulator
GGS_RS06655	COG1484	DNA-dependent DNA replication
GGS_RS06700	COG4109	DRTGG domain
GGS_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
GGS_RS06730	COG1312	Catalyzes the dehydration of D-mannonate
GGS_RS06740	COG0800	Aldolase
GGS_RS06745	COG2186	Transcriptional regulator
GGS_RS06760	COG2211	Major facilitator Superfamily
GGS_RS06780	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GGS_RS06780	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GGS_RS06785	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GGS_RS06790	COG1956	GAF domain-containing protein
GGS_RS06810	COG0513	Belongs to the DEAD box helicase family
GGS_RS06815	COG0726	polysaccharide deacetylase
GGS_RS06835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GGS_RS06845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGS_RS06865	COG1476	TRANSCRIPTIONal
GGS_RS06890	COG4122	O-methyltransferase activity
GGS_RS06895	COG2223	nitrite transmembrane transporter activity
GGS_RS06910	COG0431	NADPH-dependent FMN reductase
GGS_RS06930	COG1187	pseudouridine synthase activity
GGS_RS06965	COG0658	competence protein
GGS_RS06965	COG2333	competence protein COMEC
GGS_RS06970	COG1596	polysaccharide export
GGS_RS06970	COG1555	photosystem II stabilization
GGS_RS06975	COG0204	Acyl-transferase
GGS_RS06980	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GGS_RS06995	COG0513	Belongs to the DEAD box helicase family
GGS_RS07000	COG1464	Belongs to the NlpA lipoprotein family
GGS_RS07010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GGS_RS07030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GGS_RS07045	COG0768	penicillin binding
GGS_RS07050	COG2116	formate transmembrane transporter activity
GGS_RS07060	COG1827	regulation of RNA biosynthetic process
GGS_RS07075	COG2217	Heavy metal translocating P-type atpase
GGS_RS07100	COG2755	lipolytic protein G-D-S-L family
GGS_RS07125	COG0497	DNA recombination
GGS_RS07130	COG1438	arginine binding
GGS_RS07135	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GGS_RS07155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GGS_RS07165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGS_RS07170	COG0415	Belongs to the DNA photolyase family
GGS_RS07195	COG0765	amino acid transport
GGS_RS07200	COG4703	Protein of unknown function (DUF1797)
GGS_RS07205	COG0542	response to heat
GGS_RS07225	COG3599	regulation of cell shape
GGS_RS07245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GGS_RS07255	COG0849	cell division
GGS_RS07295	COG1217	gtp-binding protein TYPA
GGS_RS07300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGS_RS07305	COG1940	carbohydrate kinase activity
GGS_RS07315	COG0783	Belongs to the Dps family
GGS_RS07325	COG1132	(ABC) transporter
GGS_RS07330	COG1132	(ABC) transporter
GGS_RS07340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GGS_RS07345	COG4470	Protein conserved in bacteria
GGS_RS07370	COG1172	Belongs to the binding-protein-dependent transport system permease family
GGS_RS07380	COG1869	D-ribose catabolic process
GGS_RS07385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGS_RS07390	COG1609	Transcriptional regulator
GGS_RS07395	COG3480	Lon protease (S16) C-terminal proteolytic domain
GGS_RS07405	COG0742	ribosomal rna small subunit methyltransferase
GGS_RS07415	COG0549	Belongs to the carbamate kinase family
GGS_RS07425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGS_RS07430	COG1288	antiporter activity
GGS_RS07440	COG0454	-acetyltransferase
GGS_RS07445	COG2235	arginine
GGS_RS07450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGS_RS07470	COG2972	Histidine kinase
GGS_RS07475	COG2207	Transcriptional regulator
GGS_RS07475	COG4753	response regulator
GGS_RS07485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGS_RS07490	COG0785	Cytochrome C biogenesis protein
GGS_RS07500	COG0673	inositol 2-dehydrogenase activity
GGS_RS07505	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GGS_RS07510	COG1518	maintenance of DNA repeat elements
GGS_RS07555	COG0346	lactoylglutathione lyase activity
GGS_RS07575	COG0534	Mate efflux family protein
GGS_RS07585	COG1605	Chorismate mutase
GGS_RS07585	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GGS_RS07620	COG3250	beta-galactosidase activity
GGS_RS07625	COG4753	response regulator
GGS_RS07625	COG2207	Transcriptional regulator
GGS_RS07630	COG2972	Histidine kinase
GGS_RS07640	COG1653	transport
GGS_RS07645	COG0395	ABC-type sugar transport system, permease component
GGS_RS07650	COG1175	transmembrane transport
GGS_RS07655	COG1940	carbohydrate kinase activity
GGS_RS07670	COG2723	6-phospho-beta-galactosidase activity
GGS_RS07675	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GGS_RS07690	COG0383	alpha-mannosidase activity
GGS_RS07705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GGS_RS07715	COG2070	2-Nitropropane dioxygenase
GGS_RS07720	COG0183	Belongs to the thiolase family
GGS_RS07725	COG1250	3-hydroxyacyl-CoA dehydrogenase
GGS_RS07725	COG1024	Enoyl-CoA hydratase
GGS_RS07840	COG3843	relaxase mobilization nuclease domain protein
GGS_RS07895	COG1388	LysM domain
GGS_RS07895	COG3942	CHAP domain
GGS_RS07965	COG3620	sequence-specific DNA binding
GGS_RS07995	COG1040	competence protein
GGS_RS08000	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GGS_RS08005	COG1739	Uncharacterized protein family UPF0029
GGS_RS08015	COG1098	S1 RNA binding domain
GGS_RS08025	COG2197	response regulator
GGS_RS08030	COG4585	Histidine kinase
GGS_RS08040	COG2815	serine threonine protein kinase
GGS_RS08040	COG0515	serine threonine protein kinase
GGS_RS08050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GGS_RS08050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGS_RS08060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GGS_RS08080	COG0583	DNA-binding transcription factor activity
GGS_RS08085	COG0183	Belongs to the thiolase family
GGS_RS08090	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GGS_RS08100	COG1028	Short-chain dehydrogenase reductase Sdr
GGS_RS08140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GGS_RS08145	COG3579	cysteine-type endopeptidase activity
GGS_RS08155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GGS_RS08160	COG1113	amino acid transport
GGS_RS08165	COG0492	ferredoxin-NADP+ reductase activity
GGS_RS08175	COG1126	abc transporter atp-binding protein
GGS_RS08180	COG0765	amino acid transport
GGS_RS08190	COG0513	Belongs to the DEAD box helicase family
GGS_RS08200	COG0768	penicillin binding
GGS_RS08230	COG1131	(ABC) transporter
GGS_RS08255	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGS_RS08260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GGS_RS08295	COG1755	Isoprenylcysteine carboxyl methyltransferase
GGS_RS08300	COG0656	L-ascorbic acid biosynthetic process
GGS_RS08310	COG1283	sodium-dependent phosphate transmembrane transporter activity
GGS_RS08330	COG0561	phosphatase activity
GGS_RS08335	COG2860	membrane
GGS_RS08345	COG1105	Belongs to the carbohydrate kinase PfkB family
GGS_RS08370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGS_RS08385	COG2217	Heavy metal translocating P-type atpase
GGS_RS08420	COG4509	Sortase family
GGS_RS08480	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GGS_RS08485	COG0195	Participates in both transcription termination and antitermination
GGS_RS08510	COG4473	ABC transporter
GGS_RS08515	COG1131	(ABC) transporter
GGS_RS08520	COG0537	adenosine 5'-monophosphoramidase activity
GGS_RS08530	COG1316	TRANSCRIPTIONal
GGS_RS08535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGS_RS08540	COG0802	atpase or kinase
GGS_RS08545	COG2252	PERMEase
GGS_RS08550	COG0561	phosphatase activity
GGS_RS08560	COG3715	PTS system
GGS_RS08565	COG3716	PTS system mannose fructose sorbose family IID component
GGS_RS08595	COG0439	Biotin carboxylase
GGS_RS08610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GGS_RS08615	COG1028	Short-chain dehydrogenase reductase Sdr
GGS_RS08620	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GGS_RS08625	COG2070	2-Nitropropane dioxygenase
GGS_RS08645	COG1024	Enoyl-CoA hydratase
GGS_RS08650	COG0484	heat shock protein binding
GGS_RS08670	COG1420	regulation of RNA biosynthetic process
GGS_RS08685	COG0588	phosphoglycerate mutase activity
GGS_RS08690	COG2261	transglycosylase associated protein
GGS_RS08695	COG0697	spore germination
GGS_RS08715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GGS_RS08715	COG0574	Belongs to the PEP-utilizing enzyme family
GGS_RS08720	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GGS_RS08725	COG0517	IMP dehydrogenase activity
GGS_RS08735	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGS_RS08745	COG1937	Protein conserved in bacteria
GGS_RS08750	COG1335	isochorismatase
GGS_RS08760	COG0436	Aminotransferase
GGS_RS08770	COG0561	phosphatase activity
GGS_RS08775	COG0252	asparaginase activity
GGS_RS08780	COG4989	oxidoreductase activity
GGS_RS08790	COG1129	ABC transporter
GGS_RS08805	COG1132	(ABC) transporter
GGS_RS08815	COG1120	ATPase activity
GGS_RS08840	COG1388	LysM domain
GGS_RS08840	COG3942	CHAP domain
GGS_RS08865	COG1482	cell wall glycoprotein biosynthetic process
GGS_RS08870	COG1940	carbohydrate kinase activity
GGS_RS08875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGS_RS08875	COG2190	(PTS) system
GGS_RS08875	COG1263	PTS System
GGS_RS08880	COG1621	beta-fructofuranosidase activity
GGS_RS08885	COG1609	Transcriptional regulator
GGS_RS08905	COG2131	deaminase
GGS_RS08910	COG0006	proline dipeptidase activity
GGS_RS08950	COG1194	a g-specific adenine glycosylase
GGS_RS08955	COG3118	belongs to the thioredoxin family
GGS_RS08985	COG0681	Belongs to the peptidase S26 family
GGS_RS08990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGS_RS09005	COG1882	Formate acetyltransferase
GGS_RS09010	COG2153	protein acetylation
GGS_RS09020	COG1653	transport
GGS_RS09030	COG0395	ABC-type sugar transport system, permease component
GGS_RS09035	COG4209	transmembrane transport
GGS_RS09045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GGS_RS09060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GGS_RS09130	COG1132	(ABC) transporter
GGS_RS09140	COG1309	transcriptional regulator
GGS_RS09155	COG0582	viral genome integration into host DNA
GGS_RS09165	COG0789	Transcriptional regulator
GGS_RS09180	COG2081	HI0933 family
GGS_RS09205	COG1214	PFAM Peptidase M22, glycoprotease
GGS_RS09210	COG5503	Protein of unknown function (DUF1447)
GGS_RS09220	COG4608	Belongs to the ABC transporter superfamily
GGS_RS09225	COG0444	Belongs to the ABC transporter superfamily
GGS_RS09230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGS_RS09235	COG0601	transmembrane transport
GGS_RS09240	COG4166	transmembrane transport
GGS_RS09245	COG0174	glutamine synthetase
GGS_RS09250	COG0789	Transcriptional regulator
GGS_RS09270	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GGS_RS09300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GGS_RS09315	COG1564	THIamine pyrophosphokinase
GGS_RS09340	COG0084	hydrolase, TatD family'
GGS_RS09345	COG1335	isochorismatase
GGS_RS09360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGS_RS09375	COG0395	ABC-type sugar transport system, permease component
GGS_RS09380	COG1175	transmembrane transport
GGS_RS09400	COG1847	R3H domain protein
GGS_RS09465	COG0756	dUTP diphosphatase activity
GGS_RS09475	COG1132	(ABC) transporter
GGS_RS09480	COG1132	(ABC) transporter
GGS_RS09495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GGS_RS09505	COG0457	Tetratricopeptide repeat
GGS_RS09505	COG0705	Rhomboid family
GGS_RS09510	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GGS_RS09550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGS_RS09575	COG4869	propanediol catabolic process
GGS_RS09580	COG1454	alcohol dehydrogenase
GGS_RS09580	COG1012	belongs to the aldehyde dehydrogenase family
GGS_RS09595	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
GGS_RS09625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGS_RS09630	COG1882	Formate acetyltransferase
GGS_RS09635	COG1012	belongs to the aldehyde dehydrogenase family
GGS_RS09635	COG1454	alcohol dehydrogenase
GGS_RS09640	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GGS_RS09645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
GGS_RS09665	COG4978	Transcriptional regulator
GGS_RS09665	COG0789	Transcriptional regulator
GGS_RS09685	COG1234	tRNA 3'-trailer cleavage
GGS_RS09690	COG1268	BioY protein
GGS_RS09715	COG1832	CoA-binding protein
GGS_RS09720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGS_RS09720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGS_RS09730	COG4175	Glycine betaine
GGS_RS09730	COG3448	diguanylate cyclase activity
GGS_RS09735	COG1597	lipid kinase activity
GGS_RS09760	COG3623	hexulose-6-phosphate isomerase
GGS_RS09815	COG1132	(ABC) transporter
GGS_RS09820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GGS_RS09865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GGS_RS09880	COG0564	pseudouridine synthase activity
GGS_RS09895	COG1051	belongs to the nudix hydrolase family
GGS_RS09910	COG0542	response to heat
GGS_RS09915	COG4463	regulation of RNA biosynthetic process
GGS_RS09940	COG0450	alkyl hydroperoxide reductase
GGS_RS09955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GGS_RS09965	COG3404	Formiminotransferase-cyclodeaminase
GGS_RS09980	COG0531	amino acid
GGS_RS10000	COG5433	transposase activity
GGS_RS10015	COG3590	peptidase
GGS_RS10020	COG0366	Alpha amylase catalytic
GGS_RS10025	COG1263	PTS System
GGS_RS10025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGS_RS10030	COG2188	Transcriptional regulator
GGS_RS10040	COG2514	catechol 2,3-dioxygenase activity
GGS_RS10050	COG0602	queuosine metabolic process
GGS_RS10085	COG4472	Bacterial protein of unknown function (DUF965)
GGS_RS10090	COG1393	Belongs to the ArsC family
GGS_RS10105	COG0519	Catalyzes the synthesis of GMP from XMP
GGS_RS10115	COG2814	Major facilitator Superfamily
GGS_RS10145	COG0488	(ABC) transporter
GGS_RS10150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGS_RS10155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGS_RS10160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGS_RS10215	COG1511	domain protein
GGS_RS10225	COG2801	Transposase and inactivated derivatives
GGS_RS10240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GGS_RS10255	COG0305	Participates in initiation and elongation during chromosome replication
GGS_RS10270	COG5433	transposase activity
GGS_RS10285	COG2095	MarC family integral membrane protein
GGS_RS10295	COG1760	l-serine dehydratase
GGS_RS10300	COG1760	l-serine dehydratase
GGS_RS10330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GGS_RS10340	COG0612	Peptidase, M16
GGS_RS10365	COG0517	IMP dehydrogenase activity
GGS_RS10365	COG0516	GMP reductase activity
GGS_RS10375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGS_RS10380	COG0488	(ABC) transporter
GGS_RS10415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain