locus-tag	class	description
SEQ_RS00010	COG0592	DNA-directed DNA polymerase activity
SEQ_RS00025	COG0012	GTP binding
SEQ_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SEQ_RS00040	COG2244	polysaccharide biosynthetic process
SEQ_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SEQ_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SEQ_RS00075	COG0531	amino acid
SEQ_RS00195	COG3942	CHAP domain
SEQ_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SEQ_RS00225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SEQ_RS00240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SEQ_RS00255	COG0151	Belongs to the GarS family
SEQ_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SEQ_RS00275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SEQ_RS00290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SEQ_RS00305	COG1454	alcohol dehydrogenase
SEQ_RS00305	COG1012	belongs to the aldehyde dehydrogenase family
SEQ_RS00310	COG1063	alcohol dehydrogenase
SEQ_RS00315	COG1064	alcohol dehydrogenase
SEQ_RS00320	COG1132	(ABC) transporter
SEQ_RS00335	COG1396	sequence-specific DNA binding
SEQ_RS00340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SEQ_RS00350	COG0051	transcription antitermination factor activity, RNA binding
SEQ_RS00455	COG0201	protein transport
SEQ_RS00595	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SEQ_RS00610	COG1121	(ABC) transporter
SEQ_RS00615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SEQ_RS00625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SEQ_RS00625	COG4499	WXG100 protein secretion system (Wss), protein YukC
SEQ_RS00660	COG1136	(ABC) transporter
SEQ_RS00665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SEQ_RS00670	COG1459	type II secretion system
SEQ_RS00675	COG4537	Required for transformation and DNA binding
SEQ_RS00725	COG2801	Transposase and inactivated derivatives
SEQ_RS00735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEQ_RS00750	COG3959	Transketolase, thiamine diphosphate binding domain
SEQ_RS00755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SEQ_RS00760	COG3590	peptidase
SEQ_RS00780	COG0450	alkyl hydroperoxide reductase
SEQ_RS00790	COG0582	viral genome integration into host DNA
SEQ_RS00800	COG1396	sequence-specific DNA binding
SEQ_RS00845	COG3723	Recombinational DNA repair protein, rece pathway
SEQ_RS01045	COG1705	Flagellar rod assembly protein muramidase FlgJ
SEQ_RS01085	COG4463	regulation of RNA biosynthetic process
SEQ_RS01120	COG2801	Transposase and inactivated derivatives
SEQ_RS01145	COG2801	Transposase and inactivated derivatives
SEQ_RS01150	COG1051	belongs to the nudix hydrolase family
SEQ_RS01175	COG1116	anion transmembrane transporter activity
SEQ_RS01195	COG0564	pseudouridine synthase activity
SEQ_RS01215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SEQ_RS01270	COG3037	sugar-specific permease SgaT UlaA
SEQ_RS01290	COG3623	hexulose-6-phosphate isomerase
SEQ_RS01315	COG4175	Glycine betaine
SEQ_RS01315	COG3448	diguanylate cyclase activity
SEQ_RS01325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SEQ_RS01325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SEQ_RS01330	COG1832	CoA-binding protein
SEQ_RS01365	COG2801	Transposase and inactivated derivatives
SEQ_RS01380	COG1268	BioY protein
SEQ_RS01385	COG1234	tRNA 3'-trailer cleavage
SEQ_RS01405	COG1215	transferase activity, transferring glycosyl groups
SEQ_RS01420	COG0457	Tetratricopeptide repeat
SEQ_RS01420	COG0705	Rhomboid family
SEQ_RS01425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SEQ_RS01465	COG3732	PTS system glucitol sorbitol-specific
SEQ_RS01470	COG3730	PTS system glucitol sorbitol-specific
SEQ_RS01480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEQ_RS01480	COG3711	transcriptional antiterminator
SEQ_RS01510	COG1132	(ABC) transporter
SEQ_RS01515	COG1132	(ABC) transporter
SEQ_RS01525	COG0756	dUTP diphosphatase activity
SEQ_RS01580	COG1847	R3H domain protein
SEQ_RS01625	COG2190	(PTS) system
SEQ_RS01625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEQ_RS01625	COG1263	PTS System
SEQ_RS01655	COG1175	transmembrane transport
SEQ_RS01660	COG0395	ABC-type sugar transport system, permease component
SEQ_RS01665	COG2731	YhcH YjgK YiaL family protein
SEQ_RS01675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SEQ_RS01690	COG1737	Transcriptional regulator
SEQ_RS01695	COG0084	hydrolase, TatD family'
SEQ_RS01720	COG1564	THIamine pyrophosphokinase
SEQ_RS01735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SEQ_RS01770	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SEQ_RS01785	COG0789	Transcriptional regulator
SEQ_RS01790	COG0174	glutamine synthetase
SEQ_RS01795	COG4166	transmembrane transport
SEQ_RS01800	COG0601	transmembrane transport
SEQ_RS01805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SEQ_RS01810	COG0444	Belongs to the ABC transporter superfamily
SEQ_RS01815	COG4608	Belongs to the ABC transporter superfamily
SEQ_RS01830	COG1214	PFAM Peptidase M22, glycoprotease
SEQ_RS01860	COG2081	HI0933 family
SEQ_RS01875	COG0789	Transcriptional regulator
SEQ_RS01900	COG2801	Transposase and inactivated derivatives
SEQ_RS01905	COG5002	protein histidine kinase activity
SEQ_RS01950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SEQ_RS01955	COG2814	Major facilitator Superfamily
SEQ_RS01965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SEQ_RS01975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SEQ_RS01985	COG1882	Formate acetyltransferase
SEQ_RS02000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SEQ_RS02005	COG0681	Belongs to the peptidase S26 family
SEQ_RS02020	COG1286	toxin biosynthetic process
SEQ_RS02030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SEQ_RS02035	COG3118	belongs to the thioredoxin family
SEQ_RS02050	COG1194	a g-specific adenine glycosylase
SEQ_RS02080	COG2801	Transposase and inactivated derivatives
SEQ_RS02100	COG0006	proline dipeptidase activity
SEQ_RS02105	COG2131	deaminase
SEQ_RS02160	COG1609	Transcriptional regulator
SEQ_RS02165	COG1621	beta-fructofuranosidase activity
SEQ_RS02170	COG2190	(PTS) system
SEQ_RS02170	COG1263	PTS System
SEQ_RS02170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEQ_RS02180	COG1940	carbohydrate kinase activity
SEQ_RS02185	COG1482	cell wall glycoprotein biosynthetic process
SEQ_RS02210	COG2801	Transposase and inactivated derivatives
SEQ_RS02225	COG3942	CHAP domain
SEQ_RS02225	COG1388	LysM domain
SEQ_RS02250	COG1120	ATPase activity
SEQ_RS02255	COG4988	ABC transporter
SEQ_RS02260	COG1132	(ABC) transporter
SEQ_RS02275	COG1129	ABC transporter
SEQ_RS02280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SEQ_RS02285	COG0252	asparaginase activity
SEQ_RS02290	COG0561	phosphatase activity
SEQ_RS02300	COG0436	Aminotransferase
SEQ_RS02310	COG1335	isochorismatase
SEQ_RS02330	COG0697	spore germination
SEQ_RS02335	COG2261	transglycosylase associated protein
SEQ_RS02345	COG3830	Belongs to the UPF0237 family
SEQ_RS02355	COG0588	phosphoglycerate mutase activity
SEQ_RS02360	COG1876	peptidase activity
SEQ_RS02385	COG0484	heat shock protein binding
SEQ_RS02390	COG1024	Enoyl-CoA hydratase
SEQ_RS02410	COG2070	2-Nitropropane dioxygenase
SEQ_RS02415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SEQ_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
SEQ_RS02425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SEQ_RS02440	COG0439	Biotin carboxylase
SEQ_RS02470	COG3716	PTS system mannose fructose sorbose family IID component
SEQ_RS02475	COG3715	PTS system
SEQ_RS02495	COG2252	PERMEase
SEQ_RS02500	COG0802	atpase or kinase
SEQ_RS02510	COG1316	TRANSCRIPTIONal
SEQ_RS02520	COG0537	adenosine 5'-monophosphoramidase activity
SEQ_RS02530	COG1131	(ABC) transporter
SEQ_RS02535	COG4473	ABC transporter
SEQ_RS02565	COG0195	Participates in both transcription termination and antitermination
SEQ_RS02570	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SEQ_RS02600	COG2217	Heavy metal translocating P-type atpase
SEQ_RS02650	COG2860	membrane
SEQ_RS02655	COG0561	phosphatase activity
SEQ_RS02685	COG0656	L-ascorbic acid biosynthetic process
SEQ_RS02690	COG1136	(ABC) transporter
SEQ_RS02690	COG0577	efflux transmembrane transporter activity
SEQ_RS02695	COG1755	Isoprenylcysteine carboxyl methyltransferase
SEQ_RS02740	COG1131	(ABC) transporter
SEQ_RS02780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SEQ_RS02785	COG1393	Belongs to the ArsC family
SEQ_RS02790	COG0708	Exodeoxyribonuclease III
SEQ_RS02840	COG2801	Transposase and inactivated derivatives
SEQ_RS02890	COG0785	Cytochrome C biogenesis protein
SEQ_RS02895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SEQ_RS02905	COG4753	response regulator
SEQ_RS02905	COG2207	Transcriptional regulator
SEQ_RS02910	COG2972	Histidine kinase
SEQ_RS02915	COG2315	Protein conserved in bacteria
SEQ_RS02945	COG0454	-acetyltransferase
SEQ_RS02955	COG1288	antiporter activity
SEQ_RS02960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SEQ_RS02965	COG0549	Belongs to the carbamate kinase family
SEQ_RS02975	COG0742	ribosomal rna small subunit methyltransferase
SEQ_RS02985	COG3480	Lon protease (S16) C-terminal proteolytic domain
SEQ_RS02990	COG4470	Protein conserved in bacteria
SEQ_RS03005	COG0783	Belongs to the Dps family
SEQ_RS03010	COG4483	Protein conserved in bacteria
SEQ_RS03015	COG1940	carbohydrate kinase activity
SEQ_RS03025	COG1217	gtp-binding protein TYPA
SEQ_RS03050	COG0849	cell division
SEQ_RS03060	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SEQ_RS03080	COG3599	regulation of cell shape
SEQ_RS03095	COG0494	nUDIX hydrolase
SEQ_RS03100	COG0542	response to heat
SEQ_RS03105	COG4703	Protein of unknown function (DUF1797)
SEQ_RS03115	COG0765	amino acid transport
SEQ_RS03120	COG1126	abc transporter atp-binding protein
SEQ_RS03130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SEQ_RS03140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SEQ_RS03160	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SEQ_RS03165	COG1438	arginine binding
SEQ_RS03170	COG0497	DNA recombination
SEQ_RS03185	COG2755	lipolytic protein G-D-S-L family
SEQ_RS03190	COG4698	Protein conserved in bacteria
SEQ_RS03210	COG1396	sequence-specific DNA binding
SEQ_RS03230	COG1827	regulation of RNA biosynthetic process
SEQ_RS03240	COG2116	formate transmembrane transporter activity
SEQ_RS03245	COG0768	penicillin binding
SEQ_RS03265	COG2801	Transposase and inactivated derivatives
SEQ_RS03280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SEQ_RS03295	COG0513	Belongs to the DEAD box helicase family
SEQ_RS03305	COG2801	Transposase and inactivated derivatives
SEQ_RS03320	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SEQ_RS03325	COG0204	Acyl-transferase
SEQ_RS03335	COG0658	competence protein
SEQ_RS03335	COG2333	competence protein COMEC
SEQ_RS03365	COG1187	pseudouridine synthase activity
SEQ_RS03380	COG2801	Transposase and inactivated derivatives
SEQ_RS03405	COG0546	phosphoglycolate phosphatase activity
SEQ_RS03410	COG4122	O-methyltransferase activity
SEQ_RS03430	COG0726	polysaccharide deacetylase
SEQ_RS03435	COG0513	Belongs to the DEAD box helicase family
SEQ_RS03455	COG1956	GAF domain-containing protein
SEQ_RS03460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SEQ_RS03470	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SEQ_RS03470	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SEQ_RS03495	COG2801	Transposase and inactivated derivatives
SEQ_RS03510	COG2211	Major facilitator Superfamily
SEQ_RS03520	COG3250	beta-galactosidase activity
SEQ_RS03525	COG2186	Transcriptional regulator
SEQ_RS03530	COG0800	Aldolase
SEQ_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
SEQ_RS03570	COG4109	DRTGG domain
SEQ_RS03575	COG0024	Methionine aminopeptidase
SEQ_RS03595	COG1316	TRANSCRIPTIONal
SEQ_RS03600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SEQ_RS03685	COG2801	Transposase and inactivated derivatives
SEQ_RS03750	COG2801	Transposase and inactivated derivatives
SEQ_RS03770	COG1373	ATPase (AAA superfamily
SEQ_RS03775	COG0588	phosphoglycerate mutase activity
SEQ_RS03785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SEQ_RS03790	COG3859	Proton-coupled thiamine transporter YuaJ
SEQ_RS03810	COG0386	Belongs to the glutathione peroxidase family
SEQ_RS03825	COG0772	Belongs to the SEDS family
SEQ_RS03830	COG2801	Transposase and inactivated derivatives
SEQ_RS03840	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SEQ_RS03850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SEQ_RS03855	COG2884	Cell division ATP-binding protein ftsE
SEQ_RS03860	COG2177	Part of the ABC transporter FtsEX involved in
SEQ_RS03870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SEQ_RS03870	COG1199	ATP-dependent helicase activity
SEQ_RS03870	COG1199	ATP-dependent helicase activity
SEQ_RS03870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SEQ_RS03875	COG4974	Belongs to the 'phage' integrase family
SEQ_RS03895	COG2801	Transposase and inactivated derivatives
SEQ_RS04000	COG1598	PFAM Uncharacterised protein family UPF0150
SEQ_RS04130	COG0860	N-Acetylmuramoyl-L-alanine amidase
SEQ_RS04130	COG1388	LysM domain
SEQ_RS04165	COG0436	Aminotransferase
SEQ_RS04170	COG0017	Asparaginyl-tRNA synthetase
SEQ_RS04205	COG2188	Transcriptional regulator
SEQ_RS04210	COG2222	sugar isomerase
SEQ_RS04215	COG3684	Belongs to the aldolase LacD family
SEQ_RS04220	COG2188	Transcriptional regulator
SEQ_RS04230	COG2801	Transposase and inactivated derivatives
SEQ_RS04245	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEQ_RS04245	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEQ_RS04255	COG3716	PTS system mannose fructose sorbose family IID component
SEQ_RS04270	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SEQ_RS04275	COG2153	protein acetylation
SEQ_RS04285	COG0716	FMN binding
SEQ_RS04295	COG0038	chloride channel
SEQ_RS04315	COG1476	TRANSCRIPTIONal
SEQ_RS04335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SEQ_RS04340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SEQ_RS04345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEQ_RS04355	COG1012	belongs to the aldehyde dehydrogenase family
SEQ_RS04360	COG0772	Belongs to the SEDS family
SEQ_RS04420	COG4708	membrane
SEQ_RS04430	COG1597	lipid kinase activity
SEQ_RS04435	COG1523	belongs to the glycosyl hydrolase 13 family
SEQ_RS04445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SEQ_RS04450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SEQ_RS04460	COG0058	SHG alpha-glucan phosphorylase activity
SEQ_RS04510	COG2801	Transposase and inactivated derivatives
SEQ_RS04550	COG0577	efflux transmembrane transporter activity
SEQ_RS04615	COG1523	belongs to the glycosyl hydrolase 13 family
SEQ_RS04620	COG1595	DNA-templated transcription, initiation
SEQ_RS04660	COG1074	ATP-dependent DNA helicase activity
SEQ_RS04665	COG0436	Aminotransferase
SEQ_RS04670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SEQ_RS04680	COG1970	mechanosensitive ion channel activity
SEQ_RS04685	COG0358	DNA primase activity
SEQ_RS04690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SEQ_RS04695	COG2151	metal-sulfur cluster biosynthetic enzyme
SEQ_RS04700	COG1091	dTDP-4-dehydrorhamnose reductase activity
SEQ_RS04710	COG1215	transferase activity, transferring glycosyl groups
SEQ_RS04735	COG0463	Glycosyl transferase, family 2
SEQ_RS04755	COG0297	glycogen (starch) synthase activity
SEQ_RS04760	COG1368	sulfuric ester hydrolase activity
SEQ_RS04765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SEQ_RS04815	COG1368	sulfuric ester hydrolase activity
SEQ_RS04830	COG2801	Transposase and inactivated derivatives
SEQ_RS04840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SEQ_RS04860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SEQ_RS04870	COG1104	cysteine desulfurase activity
SEQ_RS04905	COG1131	(ABC) transporter
SEQ_RS04910	COG1725	Transcriptional regulator
SEQ_RS04925	COG2801	Transposase and inactivated derivatives
SEQ_RS04945	COG0469	pyruvate kinase activity
SEQ_RS04960	COG2824	Alkylphosphonate utilization operon protein PhnA
SEQ_RS04965	COG0765	amino acid transport
SEQ_RS04970	COG1126	abc transporter atp-binding protein
SEQ_RS04975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SEQ_RS04980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SEQ_RS04985	COG1115	amino acid carrier protein
SEQ_RS05035	COG4591	ABC-type transport system involved in lipoprotein release permease component
SEQ_RS05035	COG1136	(ABC) transporter
SEQ_RS05070	COG0196	riboflavin kinase activity
SEQ_RS05085	COG0483	inositol monophosphate 1-phosphatase activity
SEQ_RS05090	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SEQ_RS05090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SEQ_RS05100	COG0573	inorganic phosphate transmembrane transporter activity
SEQ_RS05105	COG0581	inorganic phosphate transmembrane transporter activity
SEQ_RS05120	COG0704	Plays a role in the regulation of phosphate uptake
SEQ_RS05130	COG0745	RESPONSE REGULATOR receiver
SEQ_RS05135	COG5002	protein histidine kinase activity
SEQ_RS05170	COG2813	Specifically methylates the guanine in position
SEQ_RS05175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SEQ_RS05190	COG1744	ABC transporter substrate-binding protein PnrA-like
SEQ_RS05195	COG3845	ABC transporter
SEQ_RS05200	COG4603	Belongs to the binding-protein-dependent transport system permease family
SEQ_RS05215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SEQ_RS05225	COG2801	Transposase and inactivated derivatives
SEQ_RS05240	COG4684	Psort location CytoplasmicMembrane, score
SEQ_RS05245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SEQ_RS05270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SEQ_RS05280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SEQ_RS05285	COG1328	CTP reductase activity
SEQ_RS05285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SEQ_RS05290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SEQ_RS05305	COG0488	(ABC) transporter
SEQ_RS05320	COG1272	protein, Hemolysin III
SEQ_RS05330	COG2226	methyltransferase
SEQ_RS05355	COG1131	(ABC) transporter
SEQ_RS05365	COG2801	Transposase and inactivated derivatives
SEQ_RS05385	COG1132	(ABC) transporter
SEQ_RS05415	COG3425	synthase
SEQ_RS05425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SEQ_RS05455	COG0105	UTP biosynthetic process
SEQ_RS05465	COG0726	polysaccharide deacetylase
SEQ_RS05470	COG0460	homoserine dehydrogenase
SEQ_RS05480	COG0285	dihydrofolate synthase activity
SEQ_RS05485	COG0302	gtp cyclohydrolase
SEQ_RS05500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SEQ_RS05515	COG1176	ABC-type spermidine putrescine transport system, permease component I
SEQ_RS05520	COG1177	transmembrane transport
SEQ_RS05540	COG0628	permease
SEQ_RS05550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SEQ_RS05565	COG1104	cysteine desulfurase activity
SEQ_RS05580	COG2357	RelA SpoT domain protein
SEQ_RS05590	COG0564	pseudouridine synthase activity
SEQ_RS05595	COG0280	phosphate acetyltransferase
SEQ_RS05600	COG4221	oxidoreductase activity
SEQ_RS05635	COG2801	Transposase and inactivated derivatives
SEQ_RS05650	COG1942	4-Oxalocrotonate Tautomerase
SEQ_RS05665	COG2890	protein-(glutamine-N5) methyltransferase activity
SEQ_RS05670	COG0009	L-threonylcarbamoyladenylate synthase
SEQ_RS05710	COG3764	Sortase (surface protein transpeptidase)
SEQ_RS05715	COG0346	lactoylglutathione lyase activity
SEQ_RS05720	COG0803	Belongs to the bacterial solute-binding protein 9 family
SEQ_RS05740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SEQ_RS05750	COG2188	Transcriptional regulator
SEQ_RS05765	COG1396	sequence-specific DNA binding
SEQ_RS05780	COG2205	protein histidine kinase activity
SEQ_RS05785	COG0745	RESPONSE REGULATOR receiver
SEQ_RS05800	COG2801	Transposase and inactivated derivatives
SEQ_RS05805	COG0577	efflux transmembrane transporter activity
SEQ_RS05810	COG1136	(ABC) transporter
SEQ_RS05860	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SEQ_RS05865	COG0511	ligase activity, forming carbon-carbon bonds
SEQ_RS05875	COG2851	Citrate transporter
SEQ_RS05895	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SEQ_RS05900	COG2801	Transposase and inactivated derivatives
SEQ_RS05935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SEQ_RS05940	COG0758	DNA mediated transformation
SEQ_RS05950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SEQ_RS05975	COG2801	Transposase and inactivated derivatives
SEQ_RS06010	COG1132	(ABC) transporter
SEQ_RS06020	COG1129	ABC transporter
SEQ_RS06045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SEQ_RS06045	COG2226	methyltransferase
SEQ_RS06045	COG3433	isochorismatase activity
SEQ_RS06050	COG1021	2,3-dihydroxybenzoate-AMP ligase
SEQ_RS06105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SEQ_RS06105	COG0551	DNA topoisomerase type I activity
SEQ_RS06170	COG1136	(ABC) transporter
SEQ_RS06170	COG0577	efflux transmembrane transporter activity
SEQ_RS06185	COG2205	protein histidine kinase activity
SEQ_RS06185	COG0784	Response regulator, receiver
SEQ_RS06195	COG1475	DNA binding
SEQ_RS06200	COG1192	Involved in chromosome partitioning
SEQ_RS06205	COG1132	(ABC) transporter
SEQ_RS06210	COG1132	(ABC) transporter
SEQ_RS06215	COG0737	Belongs to the 5'-nucleotidase family
SEQ_RS06220	COG0242	peptide deformylase activity
SEQ_RS06225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SEQ_RS06260	COG2801	Transposase and inactivated derivatives
SEQ_RS06270	COG1388	LysM domain
SEQ_RS06270	COG1705	Flagellar rod assembly protein muramidase FlgJ
SEQ_RS06295	COG1476	TRANSCRIPTIONal
SEQ_RS06305	COG1705	Flagellar rod assembly protein muramidase FlgJ
SEQ_RS06305	COG1388	LysM domain
SEQ_RS06310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEQ_RS06310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SEQ_RS06310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SEQ_RS06315	COG1105	Belongs to the carbohydrate kinase PfkB family
SEQ_RS06320	COG1349	DNA-binding transcription factor activity
SEQ_RS06355	COG1837	Belongs to the UPF0109 family
SEQ_RS06370	COG0577	efflux transmembrane transporter activity
SEQ_RS06375	COG1136	(ABC) transporter
SEQ_RS06380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SEQ_RS06415	COG0564	pseudouridine synthase activity
SEQ_RS06470	COG2801	Transposase and inactivated derivatives
SEQ_RS06495	COG0539	negative regulation of cytoplasmic translation
SEQ_RS06515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SEQ_RS06530	COG0187	DNA topoisomerase II activity
SEQ_RS06555	COG0765	amino acid transport
SEQ_RS06560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SEQ_RS06575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SEQ_RS06590	COG0583	DNA-binding transcription factor activity
SEQ_RS06660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SEQ_RS06675	COG1840	ABC-type Fe3 transport system, periplasmic component
SEQ_RS06680	COG2207	Transcriptional regulator
SEQ_RS06680	COG4753	response regulator
SEQ_RS06685	COG2972	Histidine kinase
SEQ_RS06690	COG3716	PTS system mannose fructose sorbose family IID component
SEQ_RS06695	COG3715	PTS system
SEQ_RS06745	COG2274	protein secretion by the type I secretion system
SEQ_RS06750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SEQ_RS06795	COG0647	UMP catabolic process
SEQ_RS06805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SEQ_RS06825	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SEQ_RS06830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SEQ_RS06835	COG3442	glutamine amidotransferase
SEQ_RS06840	COG0095	Lipoate-protein ligase
SEQ_RS06850	COG0508	dehydrogenase complex catalyzes the overall conversion of
SEQ_RS06855	COG0508	dehydrogenase complex catalyzes the overall conversion of
SEQ_RS06855	COG0022	dehydrogenase e1 component
SEQ_RS06860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SEQ_RS06865	COG0488	(ABC) transporter
SEQ_RS06880	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SEQ_RS06895	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SEQ_RS06900	COG0457	Tetratricopeptide repeat
SEQ_RS06905	COG0628	permease
SEQ_RS06910	COG1051	belongs to the nudix hydrolase family
SEQ_RS06915	COG1088	dTDP-glucose 4,6-dehydratase activity
SEQ_RS06925	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SEQ_RS06930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SEQ_RS06940	COG2384	SAM-dependent methyltransferase
SEQ_RS06945	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SEQ_RS06965	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SEQ_RS06965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SEQ_RS06970	COG0300	oxidoreductase activity
SEQ_RS06980	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SEQ_RS06985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SEQ_RS07000	COG0058	SHG alpha-glucan phosphorylase activity
SEQ_RS07005	COG1640	4-alpha-glucanotransferase
SEQ_RS07010	COG1609	Transcriptional regulator
SEQ_RS07020	COG1175	transmembrane transport
SEQ_RS07025	COG3833	ABC-type maltose transport systems, permease component
SEQ_RS07035	COG2801	Transposase and inactivated derivatives
SEQ_RS07045	COG3833	ABC-type maltose transport systems, permease component
SEQ_RS07050	COG1175	transmembrane transport
SEQ_RS07060	COG0366	Alpha amylase catalytic
SEQ_RS07065	COG2182	Extracellular solute-binding protein
SEQ_RS07070	COG0657	acetylesterase activity
SEQ_RS07075	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SEQ_RS07085	COG1696	Membrane protein involved in D-alanine export
SEQ_RS07105	COG0765	amino acid transport
SEQ_RS07110	COG1126	abc transporter atp-binding protein
SEQ_RS07115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEQ_RS07125	COG1447	Phosphotransferase system cellobiose-specific component IIA
SEQ_RS07135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEQ_RS07135	COG3711	transcriptional antiterminator
SEQ_RS07145	COG2723	6-phospho-beta-galactosidase activity
SEQ_RS07165	COG2309	aminopeptidase activity
SEQ_RS07165	COG2309	aminopeptidase activity
SEQ_RS07170	COG1187	pseudouridine synthase activity
SEQ_RS07180	COG2814	Major facilitator Superfamily
SEQ_RS07200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SEQ_RS07215	COG2801	Transposase and inactivated derivatives
SEQ_RS07225	COG0800	Aldolase
SEQ_RS07230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SEQ_RS07240	COG1028	Short-chain dehydrogenase reductase Sdr
SEQ_RS07255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEQ_RS07260	COG3715	PTS system
SEQ_RS07265	COG3716	PTS system mannose fructose sorbose family IID component
SEQ_RS07270	COG1609	Transcriptional regulator
SEQ_RS07310	COG1078	dGTPase activity
SEQ_RS07405	COG2801	Transposase and inactivated derivatives
SEQ_RS07435	COG4443	Transcriptional Coactivator p15 (PC4)
SEQ_RS07445	COG0826	peptidase U32
SEQ_RS07495	COG2183	response to ionizing radiation
SEQ_RS07505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SEQ_RS07515	COG0573	inorganic phosphate transmembrane transporter activity
SEQ_RS07520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SEQ_RS07525	COG5002	protein histidine kinase activity
SEQ_RS07530	COG0745	RESPONSE REGULATOR receiver
SEQ_RS07540	COG0701	Predicted permease
SEQ_RS07545	COG3689	TIGRFAM TIGR03943 family protein
SEQ_RS07555	COG2190	(PTS) system
SEQ_RS07555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEQ_RS07555	COG1263	PTS System
SEQ_RS07560	COG3711	transcriptional antiterminator
SEQ_RS07565	COG0552	protein localization to endoplasmic reticulum
SEQ_RS07570	COG0561	phosphatase activity
SEQ_RS07575	COG0561	phosphatase activity
SEQ_RS07585	COG1136	(ABC) transporter
SEQ_RS07615	COG1196	nuclear chromosome segregation
SEQ_RS07645	COG2801	Transposase and inactivated derivatives
SEQ_RS07655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SEQ_RS07660	COG5002	protein histidine kinase activity
SEQ_RS07665	COG0745	RESPONSE REGULATOR receiver
SEQ_RS07680	COG0183	Belongs to the thiolase family
SEQ_RS07695	COG2801	Transposase and inactivated derivatives
SEQ_RS07700	COG1131	(ABC) transporter
SEQ_RS07725	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SEQ_RS07730	COG0438	transferase activity, transferring glycosyl groups
SEQ_RS07745	COG1609	Transcriptional regulator
SEQ_RS07750	COG0006	proline dipeptidase activity
SEQ_RS07760	COG2274	protein secretion by the type I secretion system
SEQ_RS07775	COG0463	Glycosyl transferase, family 2
SEQ_RS07785	COG0557	exoribonuclease II activity
SEQ_RS07830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEQ_RS07835	COG1447	Phosphotransferase system cellobiose-specific component IIA
SEQ_RS07840	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEQ_RS07850	COG1940	carbohydrate kinase activity
SEQ_RS07870	COG2801	Transposase and inactivated derivatives
SEQ_RS07875	COG2610	gluconate transmembrane transporter activity
SEQ_RS07880	COG1028	Short-chain dehydrogenase reductase Sdr
SEQ_RS07890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SEQ_RS07895	COG0183	Belongs to the thiolase family
SEQ_RS07900	COG0583	DNA-binding transcription factor activity
SEQ_RS07910	COG1131	(ABC) transporter
SEQ_RS07925	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SEQ_RS07940	COG1573	uracil-dna glycosylase
SEQ_RS07945	COG1702	phosphate starvation-inducible protein PhoH
SEQ_RS07950	COG4479	Belongs to the UPF0346 family
SEQ_RS07980	COG0444	Belongs to the ABC transporter superfamily
SEQ_RS07985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SEQ_RS07990	COG0601	transmembrane transport
SEQ_RS07995	COG0747	negative chemotaxis
SEQ_RS08060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SEQ_RS08080	COG0673	inositol 2-dehydrogenase activity
SEQ_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
SEQ_RS08120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SEQ_RS08145	COG1605	Chorismate mutase
SEQ_RS08145	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SEQ_RS08165	COG3250	beta-galactosidase activity
SEQ_RS08170	COG2207	Transcriptional regulator
SEQ_RS08170	COG4753	response regulator
SEQ_RS08175	COG2972	Histidine kinase
SEQ_RS08185	COG1653	transport
SEQ_RS08190	COG0395	ABC-type sugar transport system, permease component
SEQ_RS08195	COG1175	transmembrane transport
SEQ_RS08200	COG1940	carbohydrate kinase activity
SEQ_RS08210	COG2723	6-phospho-beta-galactosidase activity
SEQ_RS08215	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SEQ_RS08215	COG3291	Pkd domain containing protein
SEQ_RS08230	COG0383	alpha-mannosidase activity
SEQ_RS08235	COG1136	(ABC) transporter
SEQ_RS08260	COG2801	Transposase and inactivated derivatives
SEQ_RS08290	COG2274	protein secretion by the type I secretion system
SEQ_RS08305	COG3290	protein histidine kinase activity
SEQ_RS08420	COG1040	competence protein
SEQ_RS08440	COG1705	Flagellar rod assembly protein muramidase FlgJ
SEQ_RS08575	COG1783	phage Terminase large subunit
SEQ_RS08580	COG2801	Transposase and inactivated derivatives
SEQ_RS08605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SEQ_RS08610	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SEQ_RS08615	COG1739	Uncharacterized protein family UPF0029
SEQ_RS08625	COG1098	S1 RNA binding domain
SEQ_RS08635	COG2197	response regulator
SEQ_RS08640	COG4585	Histidine kinase
SEQ_RS08650	COG2815	serine threonine protein kinase
SEQ_RS08650	COG0515	serine threonine protein kinase
SEQ_RS08660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SEQ_RS08660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SEQ_RS08670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SEQ_RS08700	COG2801	Transposase and inactivated derivatives
SEQ_RS08710	COG0116	Belongs to the methyltransferase superfamily
SEQ_RS08730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SEQ_RS08735	COG3579	cysteine-type endopeptidase activity
SEQ_RS08745	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SEQ_RS08750	COG1113	amino acid transport
SEQ_RS08755	COG0492	ferredoxin-NADP+ reductase activity
SEQ_RS08765	COG1126	abc transporter atp-binding protein
SEQ_RS08775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SEQ_RS08785	COG0513	Belongs to the DEAD box helicase family
SEQ_RS08795	COG0768	penicillin binding
SEQ_RS08835	COG2801	Transposase and inactivated derivatives
SEQ_RS08850	COG1131	(ABC) transporter
SEQ_RS08910	COG1774	PSP1 C-terminal conserved region
SEQ_RS08915	COG0470	DNA polymerase III
SEQ_RS08945	COG2244	polysaccharide biosynthetic process
SEQ_RS08955	COG1120	ATPase activity
SEQ_RS08960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SEQ_RS08965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SEQ_RS08970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SEQ_RS08990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SEQ_RS08995	COG1253	flavin adenine dinucleotide binding
SEQ_RS09000	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SEQ_RS09005	COG3231	kanamycin kinase activity
SEQ_RS09010	COG1242	4 iron, 4 sulfur cluster binding
SEQ_RS09015	COG0671	phosphoesterase, PA-phosphatase related
SEQ_RS09020	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SEQ_RS09075	COG1187	pseudouridine synthase activity
SEQ_RS09130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SEQ_RS09140	COG2801	Transposase and inactivated derivatives
SEQ_RS09155	COG1254	Belongs to the acylphosphatase family
SEQ_RS09170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SEQ_RS09200	COG1484	DNA-dependent DNA replication
SEQ_RS09215	COG5002	protein histidine kinase activity
SEQ_RS09220	COG0745	RESPONSE REGULATOR receiver
SEQ_RS09235	COG1704	LemA family
SEQ_RS09245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SEQ_RS09250	COG0569	domain protein
SEQ_RS09260	COG1114	Component of the transport system for branched-chain amino acids
SEQ_RS09275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SEQ_RS09280	COG1464	Belongs to the NlpA lipoprotein family
SEQ_RS09285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SEQ_RS09295	COG0789	Transcriptional regulator
SEQ_RS09305	COG2226	methyltransferase
SEQ_RS09310	COG0799	negative regulation of ribosome biogenesis
SEQ_RS09315	COG1713	HD superfamily hydrolase involved in NAD metabolism
SEQ_RS09320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SEQ_RS09325	COG1534	Rna-binding protein
SEQ_RS09330	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SEQ_RS09335	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SEQ_RS09380	COG0444	Belongs to the ABC transporter superfamily
SEQ_RS09385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SEQ_RS09390	COG0601	transmembrane transport
SEQ_RS09395	COG4166	transmembrane transport
SEQ_RS09400	COG1686	Belongs to the peptidase S11 family
SEQ_RS09405	COG1686	Belongs to the peptidase S11 family
SEQ_RS09425	COG0719	Fe-S assembly protein
SEQ_RS09435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SEQ_RS09440	COG0719	Fe-S assembly protein
SEQ_RS09450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SEQ_RS09465	COG0765	amino acid transport
SEQ_RS09470	COG1126	abc transporter atp-binding protein
SEQ_RS09500	COG0191	fructose-bisphosphate aldolase activity
SEQ_RS09530	COG0366	Alpha amylase catalytic
SEQ_RS09535	COG0668	transmembrane transport
SEQ_RS09550	COG0352	thiamine-phosphate diphosphorylase activity
SEQ_RS09550	COG0351	phosphomethylpyrimidine kinase
SEQ_RS09560	COG0527	aspartate kinase activity
SEQ_RS09670	COG0803	Belongs to the bacterial solute-binding protein 9 family
SEQ_RS09680	COG1597	lipid kinase activity
SEQ_RS09685	COG1609	Transcriptional regulator
SEQ_RS09690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SEQ_RS09695	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SEQ_RS09700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SEQ_RS09705	COG2017	converts alpha-aldose to the beta-anomer
SEQ_RS09800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SEQ_RS09825	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SEQ_RS09835	COG1045	serine acetyltransferase
SEQ_RS09855	COG2801	Transposase and inactivated derivatives
SEQ_RS09875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SEQ_RS09880	COG1846	Transcriptional regulator
SEQ_RS09905	COG4589	Belongs to the CDS family
SEQ_RS09915	COG1862	Preprotein translocase
SEQ_RS09930	COG3842	ATPase activity
SEQ_RS09975	COG2190	(PTS) system
SEQ_RS09975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEQ_RS09975	COG1263	PTS System
SEQ_RS09985	COG1609	Transcriptional regulator
SEQ_RS09995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SEQ_RS10030	COG0512	Glutamine amidotransferase of anthranilate synthase
SEQ_RS10035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SEQ_RS10040	COG2801	Transposase and inactivated derivatives
SEQ_RS10055	COG1396	sequence-specific DNA binding
SEQ_RS10190	COG1783	phage Terminase large subunit
SEQ_RS10315	COG0582	viral genome integration into host DNA
SEQ_RS10325	COG2801	Transposase and inactivated derivatives
SEQ_RS10385	COG1882	Formate acetyltransferase
SEQ_RS10390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEQ_RS10395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEQ_RS10400	COG1447	Phosphotransferase system cellobiose-specific component IIA
SEQ_RS10410	COG1349	DNA-binding transcription factor activity
SEQ_RS10415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SEQ_RS10455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SEQ_RS10475	COG4120	Belongs to the binding-protein-dependent transport system permease family
SEQ_RS10500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SEQ_RS10505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SEQ_RS10515	COG1363	Peptidase, m42
SEQ_RS10520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SEQ_RS10550	COG0602	queuosine metabolic process
SEQ_RS10565	COG1328	CTP reductase activity
SEQ_RS10590	COG1393	Belongs to the ArsC family
SEQ_RS10620	COG0519	Catalyzes the synthesis of GMP from XMP
SEQ_RS10630	COG2814	Major facilitator Superfamily
SEQ_RS10650	COG1438	arginine binding
SEQ_RS10660	COG0488	(ABC) transporter
SEQ_RS10665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SEQ_RS10670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SEQ_RS10675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SEQ_RS10690	COG1131	(ABC) transporter
SEQ_RS10745	COG2197	response regulator
SEQ_RS10760	COG2801	Transposase and inactivated derivatives
SEQ_RS10775	COG1136	(ABC) transporter
SEQ_RS10775	COG0577	efflux transmembrane transporter activity
SEQ_RS10805	COG2801	Transposase and inactivated derivatives
SEQ_RS10825	COG1511	domain protein
SEQ_RS10845	COG0305	Participates in initiation and elongation during chromosome replication
SEQ_RS10865	COG2816	NAD+ diphosphatase activity
SEQ_RS10875	COG1760	l-serine dehydratase
SEQ_RS10880	COG1760	l-serine dehydratase
SEQ_RS10890	COG0741	lytic transglycosylase activity
SEQ_RS10910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SEQ_RS10920	COG0612	Peptidase, M16
SEQ_RS10930	COG2501	S4 domain
SEQ_RS10980	COG0516	GMP reductase activity
SEQ_RS10980	COG0517	IMP dehydrogenase activity
SEQ_RS10990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SEQ_RS10995	COG0488	(ABC) transporter
SEQ_RS11025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SEQ_RS11030	COG1475	DNA binding
SEQ_RS11055	COG0270	DNA (cytosine-5-)-methyltransferase activity