locus-tag	class	description
GJS33_RS00010	COG0592	DNA-directed DNA polymerase activity
GJS33_RS00025	COG0012	GTP binding
GJS33_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
GJS33_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GJS33_RS00040	COG2244	polysaccharide biosynthetic process
GJS33_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GJS33_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GJS33_RS00075	COG0531	amino acid
GJS33_RS00195	COG3942	CHAP domain
GJS33_RS00210	COG0416	fatty acid biosynthetic process
GJS33_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJS33_RS00240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GJS33_RS00255	COG0151	Belongs to the GarS family
GJS33_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GJS33_RS00275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GJS33_RS00290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GJS33_RS00305	COG1012	belongs to the aldehyde dehydrogenase family
GJS33_RS00305	COG1454	alcohol dehydrogenase
GJS33_RS00310	COG1063	alcohol dehydrogenase
GJS33_RS00315	COG1064	alcohol dehydrogenase
GJS33_RS00320	COG1132	(ABC) transporter
GJS33_RS00325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GJS33_RS00335	COG1396	sequence-specific DNA binding
GJS33_RS00345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GJS33_RS00360	COG0051	transcription antitermination factor activity, RNA binding
GJS33_RS00375	COG0089	rRNA binding
GJS33_RS00465	COG0201	protein transport
GJS33_RS00470	COG0563	adenylate kinase activity
GJS33_RS00500	COG0203	ribosomal protein L17
GJS33_RS00610	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GJS33_RS00625	COG1121	(ABC) transporter
GJS33_RS00630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJS33_RS00640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GJS33_RS00645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJS33_RS00645	COG4499	WXG100 protein secretion system (Wss), protein YukC
GJS33_RS00660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GJS33_RS00710	COG1136	(ABC) transporter
GJS33_RS00715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GJS33_RS00720	COG1459	type II secretion system
GJS33_RS00725	COG4537	Required for transformation and DNA binding
GJS33_RS00770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJS33_RS00785	COG3959	Transketolase, thiamine diphosphate binding domain
GJS33_RS00790	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GJS33_RS00795	COG3590	peptidase
GJS33_RS00800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GJS33_RS00810	COG5433	transposase activity
GJS33_RS00820	COG0450	alkyl hydroperoxide reductase
GJS33_RS00835	COG4463	regulation of RNA biosynthetic process
GJS33_RS00840	COG0542	response to heat
GJS33_RS00895	COG1051	belongs to the nudix hydrolase family
GJS33_RS00920	COG1116	anion transmembrane transporter activity
GJS33_RS00940	COG0564	pseudouridine synthase activity
GJS33_RS00960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJS33_RS01015	COG1131	(ABC) transporter
GJS33_RS01020	COG3037	sugar-specific permease SgaT UlaA
GJS33_RS01040	COG3623	hexulose-6-phosphate isomerase
GJS33_RS01060	COG3448	diguanylate cyclase activity
GJS33_RS01060	COG4175	Glycine betaine
GJS33_RS01070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GJS33_RS01070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GJS33_RS01075	COG1832	CoA-binding protein
GJS33_RS01100	COG0343	queuine tRNA-ribosyltransferase activity
GJS33_RS01125	COG1268	BioY protein
GJS33_RS01130	COG1234	tRNA 3'-trailer cleavage
GJS33_RS01155	COG1215	transferase activity, transferring glycosyl groups
GJS33_RS01185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJS33_RS01185	COG3711	transcriptional antiterminator
GJS33_RS01195	COG3730	PTS system glucitol sorbitol-specific
GJS33_RS01200	COG3732	PTS system glucitol sorbitol-specific
GJS33_RS01220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GJS33_RS01225	COG0705	Rhomboid family
GJS33_RS01225	COG0457	Tetratricopeptide repeat
GJS33_RS01245	COG1132	(ABC) transporter
GJS33_RS01250	COG1132	(ABC) transporter
GJS33_RS01260	COG0756	dUTP diphosphatase activity
GJS33_RS01310	COG1131	(ABC) transporter
GJS33_RS01345	COG1847	R3H domain protein
GJS33_RS01385	COG2190	(PTS) system
GJS33_RS01385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJS33_RS01385	COG1263	PTS System
GJS33_RS01390	COG2190	(PTS) system
GJS33_RS01390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJS33_RS01390	COG1263	PTS System
GJS33_RS01410	COG1175	transmembrane transport
GJS33_RS01415	COG0395	ABC-type sugar transport system, permease component
GJS33_RS01420	COG2731	YhcH YjgK YiaL family protein
GJS33_RS01430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GJS33_RS01440	COG3458	cephalosporin-C deacetylase activity
GJS33_RS01445	COG1737	Transcriptional regulator
GJS33_RS01450	COG0084	hydrolase, TatD family'
GJS33_RS01475	COG1564	THIamine pyrophosphokinase
GJS33_RS01490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJS33_RS01520	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GJS33_RS01525	COG0126	phosphoglycerate kinase activity
GJS33_RS01535	COG0789	Transcriptional regulator
GJS33_RS01540	COG0174	glutamine synthetase
GJS33_RS01545	COG4166	transmembrane transport
GJS33_RS01550	COG0601	transmembrane transport
GJS33_RS01555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJS33_RS01560	COG0444	Belongs to the ABC transporter superfamily
GJS33_RS01565	COG4608	Belongs to the ABC transporter superfamily
GJS33_RS01580	COG1214	PFAM Peptidase M22, glycoprotease
GJS33_RS01595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GJS33_RS01605	COG2081	HI0933 family
GJS33_RS01615	COG5433	transposase activity
GJS33_RS01630	COG0789	Transcriptional regulator
GJS33_RS01635	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GJS33_RS01650	COG5002	protein histidine kinase activity
GJS33_RS01690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GJS33_RS01695	COG2814	Major facilitator Superfamily
GJS33_RS01705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJS33_RS01715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GJS33_RS01725	COG1882	Formate acetyltransferase
GJS33_RS01740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GJS33_RS01745	COG0681	Belongs to the peptidase S26 family
GJS33_RS01760	COG1286	toxin biosynthetic process
GJS33_RS01770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJS33_RS01775	COG3118	belongs to the thioredoxin family
GJS33_RS01785	COG1194	a g-specific adenine glycosylase
GJS33_RS01820	COG0006	proline dipeptidase activity
GJS33_RS01825	COG2131	deaminase
GJS33_RS01865	COG1609	Transcriptional regulator
GJS33_RS01870	COG1621	beta-fructofuranosidase activity
GJS33_RS01875	COG1263	PTS System
GJS33_RS01875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJS33_RS01875	COG2190	(PTS) system
GJS33_RS01885	COG1940	carbohydrate kinase activity
GJS33_RS01890	COG1482	cell wall glycoprotein biosynthetic process
GJS33_RS01895	COG0653	protein targeting
GJS33_RS01910	COG5433	transposase activity
GJS33_RS01915	COG3942	CHAP domain
GJS33_RS01915	COG1388	LysM domain
GJS33_RS01940	COG1120	ATPase activity
GJS33_RS01945	COG4988	ABC transporter
GJS33_RS01950	COG1132	(ABC) transporter
GJS33_RS01965	COG1129	ABC transporter
GJS33_RS01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GJS33_RS01975	COG0252	asparaginase activity
GJS33_RS01980	COG0561	phosphatase activity
GJS33_RS01990	COG0436	Aminotransferase
GJS33_RS01995	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GJS33_RS02000	COG1335	isochorismatase
GJS33_RS02015	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GJS33_RS02020	COG0697	spore germination
GJS33_RS02025	COG2261	transglycosylase associated protein
GJS33_RS02035	COG3830	Belongs to the UPF0237 family
GJS33_RS02045	COG0588	phosphoglycerate mutase activity
GJS33_RS02050	COG1876	peptidase activity
GJS33_RS02060	COG1420	regulation of RNA biosynthetic process
GJS33_RS02070	COG0443	Heat shock 70 kDa protein
GJS33_RS02075	COG0484	heat shock protein binding
GJS33_RS02080	COG1024	Enoyl-CoA hydratase
GJS33_RS02090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GJS33_RS02100	COG2070	2-Nitropropane dioxygenase
GJS33_RS02105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GJS33_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
GJS33_RS02115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJS33_RS02130	COG0439	Biotin carboxylase
GJS33_RS02135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GJS33_RS02165	COG3716	PTS system mannose fructose sorbose family IID component
GJS33_RS02170	COG3715	PTS system
GJS33_RS02185	COG0561	phosphatase activity
GJS33_RS02190	COG2252	PERMEase
GJS33_RS02195	COG0802	atpase or kinase
GJS33_RS02205	COG1316	TRANSCRIPTIONal
GJS33_RS02215	COG0537	adenosine 5'-monophosphoramidase activity
GJS33_RS02225	COG1131	(ABC) transporter
GJS33_RS02230	COG4473	ABC transporter
GJS33_RS02240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GJS33_RS02260	COG0195	Participates in both transcription termination and antitermination
GJS33_RS02265	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GJS33_RS02275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GJS33_RS02295	COG2217	Heavy metal translocating P-type atpase
GJS33_RS02340	COG3711	transcriptional antiterminator
GJS33_RS02345	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJS33_RS02350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJS33_RS02350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJS33_RS02365	COG2860	membrane
GJS33_RS02370	COG0561	phosphatase activity
GJS33_RS02390	COG1283	sodium-dependent phosphate transmembrane transporter activity
GJS33_RS02400	COG0656	L-ascorbic acid biosynthetic process
GJS33_RS02410	COG1755	Isoprenylcysteine carboxyl methyltransferase
GJS33_RS02460	COG1131	(ABC) transporter
GJS33_RS02505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GJS33_RS02510	COG1393	Belongs to the ArsC family
GJS33_RS02515	COG0708	Exodeoxyribonuclease III
GJS33_RS02570	COG2274	protein secretion by the type I secretion system
GJS33_RS02600	COG1114	Component of the transport system for branched-chain amino acids
GJS33_RS02735	COG1518	maintenance of DNA repeat elements
GJS33_RS02740	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GJS33_RS02745	COG0785	Cytochrome C biogenesis protein
GJS33_RS02750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJS33_RS02760	COG2207	Transcriptional regulator
GJS33_RS02760	COG4753	response regulator
GJS33_RS02765	COG2972	Histidine kinase
GJS33_RS02770	COG2315	Protein conserved in bacteria
GJS33_RS02790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GJS33_RS02800	COG0454	-acetyltransferase
GJS33_RS02810	COG1288	antiporter activity
GJS33_RS02815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJS33_RS02820	COG0549	Belongs to the carbamate kinase family
GJS33_RS02830	COG0742	ribosomal rna small subunit methyltransferase
GJS33_RS02840	COG3480	Lon protease (S16) C-terminal proteolytic domain
GJS33_RS02845	COG4470	Protein conserved in bacteria
GJS33_RS02860	COG0783	Belongs to the Dps family
GJS33_RS02865	COG4483	Protein conserved in bacteria
GJS33_RS02870	COG1940	carbohydrate kinase activity
GJS33_RS02875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GJS33_RS02880	COG1217	gtp-binding protein TYPA
GJS33_RS02905	COG0849	cell division
GJS33_RS02915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GJS33_RS02935	COG3599	regulation of cell shape
GJS33_RS02950	COG0494	nUDIX hydrolase
GJS33_RS02955	COG0542	response to heat
GJS33_RS02960	COG4703	Protein of unknown function (DUF1797)
GJS33_RS02970	COG0765	amino acid transport
GJS33_RS02975	COG1126	abc transporter atp-binding protein
GJS33_RS02980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJS33_RS02990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GJS33_RS03015	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GJS33_RS03020	COG1438	arginine binding
GJS33_RS03025	COG0497	DNA recombination
GJS33_RS03040	COG2755	lipolytic protein G-D-S-L family
GJS33_RS03045	COG4698	Protein conserved in bacteria
GJS33_RS03065	COG1396	sequence-specific DNA binding
GJS33_RS03070	COG0167	dihydroorotate dehydrogenase activity
GJS33_RS03080	COG1827	regulation of RNA biosynthetic process
GJS33_RS03090	COG2116	formate transmembrane transporter activity
GJS33_RS03095	COG0768	penicillin binding
GJS33_RS03110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJS33_RS03125	COG0513	Belongs to the DEAD box helicase family
GJS33_RS03130	COG3158	transport of potassium into the cell
GJS33_RS03140	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GJS33_RS03145	COG0204	Acyl-transferase
GJS33_RS03155	COG2333	competence protein COMEC
GJS33_RS03155	COG0658	competence protein
GJS33_RS03180	COG0363	glucosamine-6-phosphate deaminase activity
GJS33_RS03185	COG1187	pseudouridine synthase activity
GJS33_RS03210	COG0546	phosphoglycolate phosphatase activity
GJS33_RS03215	COG4122	O-methyltransferase activity
GJS33_RS03230	COG0726	polysaccharide deacetylase
GJS33_RS03235	COG0513	Belongs to the DEAD box helicase family
GJS33_RS03255	COG1956	GAF domain-containing protein
GJS33_RS03260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GJS33_RS03270	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GJS33_RS03270	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GJS33_RS03290	COG2211	Major facilitator Superfamily
GJS33_RS03300	COG3250	beta-galactosidase activity
GJS33_RS03305	COG2186	Transcriptional regulator
GJS33_RS03310	COG0800	Aldolase
GJS33_RS03325	COG1028	Short-chain dehydrogenase reductase Sdr
GJS33_RS03350	COG4109	DRTGG domain
GJS33_RS03355	COG0024	Methionine aminopeptidase
GJS33_RS03365	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GJS33_RS03375	COG1316	TRANSCRIPTIONal
GJS33_RS03400	COG1484	DNA-dependent DNA replication
GJS33_RS03480	COG0745	RESPONSE REGULATOR receiver
GJS33_RS03485	COG5002	protein histidine kinase activity
GJS33_RS03485	COG3850	Histidine kinase
GJS33_RS03490	COG1136	(ABC) transporter
GJS33_RS03570	COG4581	dead DEAH box helicase
GJS33_RS03580	COG0588	phosphoglycerate mutase activity
GJS33_RS03590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GJS33_RS03595	COG3859	Proton-coupled thiamine transporter YuaJ
GJS33_RS03600	COG5433	transposase activity
GJS33_RS03630	COG0386	Belongs to the glutathione peroxidase family
GJS33_RS03635	COG1164	Oligoendopeptidase f
GJS33_RS03645	COG0772	Belongs to the SEDS family
GJS33_RS03650	COG1396	sequence-specific DNA binding
GJS33_RS03675	COG1131	(ABC) transporter
GJS33_RS03690	COG1132	(ABC) transporter
GJS33_RS03710	COG2884	Cell division ATP-binding protein ftsE
GJS33_RS03715	COG2177	Part of the ABC transporter FtsEX involved in
GJS33_RS03725	COG1199	ATP-dependent helicase activity
GJS33_RS03725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GJS33_RS03735	COG0436	Aminotransferase
GJS33_RS03740	COG0017	Asparaginyl-tRNA synthetase
GJS33_RS03750	COG1660	Displays ATPase and GTPase activities
GJS33_RS03775	COG2188	Transcriptional regulator
GJS33_RS03780	COG2222	sugar isomerase
GJS33_RS03785	COG3684	Belongs to the aldolase LacD family
GJS33_RS03790	COG2188	Transcriptional regulator
GJS33_RS03800	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJS33_RS03800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJS33_RS03805	COG3715	PTS system
GJS33_RS03810	COG3716	PTS system mannose fructose sorbose family IID component
GJS33_RS03820	COG0254	rRNA binding
GJS33_RS03825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GJS33_RS03830	COG2153	protein acetylation
GJS33_RS03835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GJS33_RS03840	COG0716	FMN binding
GJS33_RS03845	COG5433	transposase activity
GJS33_RS03855	COG0038	chloride channel
GJS33_RS03875	COG1476	TRANSCRIPTIONal
GJS33_RS03895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJS33_RS03900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GJS33_RS03905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJS33_RS03915	COG1012	belongs to the aldehyde dehydrogenase family
GJS33_RS03920	COG0772	Belongs to the SEDS family
GJS33_RS03990	COG4708	membrane
GJS33_RS04000	COG1597	lipid kinase activity
GJS33_RS04005	COG1523	belongs to the glycosyl hydrolase 13 family
GJS33_RS04010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GJS33_RS04015	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GJS33_RS04020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GJS33_RS04030	COG0058	SHG alpha-glucan phosphorylase activity
GJS33_RS04105	COG0577	efflux transmembrane transporter activity
GJS33_RS04170	COG1523	belongs to the glycosyl hydrolase 13 family
GJS33_RS04175	COG1595	DNA-templated transcription, initiation
GJS33_RS04210	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GJS33_RS04215	COG1074	ATP-dependent DNA helicase activity
GJS33_RS04220	COG0436	Aminotransferase
GJS33_RS04225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJS33_RS04235	COG1970	mechanosensitive ion channel activity
GJS33_RS04240	COG0358	DNA primase activity
GJS33_RS04245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GJS33_RS04250	COG2151	metal-sulfur cluster biosynthetic enzyme
GJS33_RS04255	COG1091	dTDP-4-dehydrorhamnose reductase activity
GJS33_RS04265	COG0463	Glycosyl transferase, family 2
GJS33_RS04290	COG0463	Glycosyl transferase, family 2
GJS33_RS04310	COG0297	glycogen (starch) synthase activity
GJS33_RS04315	COG1368	sulfuric ester hydrolase activity
GJS33_RS04320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJS33_RS04370	COG1368	sulfuric ester hydrolase activity
GJS33_RS04375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GJS33_RS04390	COG3679	Belongs to the UPF0342 family
GJS33_RS04395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJS33_RS04405	COG1104	cysteine desulfurase activity
GJS33_RS04410	COG0301	tRNA thio-modification
GJS33_RS04445	COG1131	(ABC) transporter
GJS33_RS04450	COG1725	Transcriptional regulator
GJS33_RS04465	COG0469	pyruvate kinase activity
GJS33_RS04480	COG2824	Alkylphosphonate utilization operon protein PhnA
GJS33_RS04485	COG0765	amino acid transport
GJS33_RS04490	COG1126	abc transporter atp-binding protein
GJS33_RS04495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJS33_RS04500	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GJS33_RS04505	COG1115	amino acid carrier protein
GJS33_RS04555	COG4591	ABC-type transport system involved in lipoprotein release permease component
GJS33_RS04555	COG1136	(ABC) transporter
GJS33_RS04585	COG0196	riboflavin kinase activity
GJS33_RS04600	COG0483	inositol monophosphate 1-phosphatase activity
GJS33_RS04605	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GJS33_RS04605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GJS33_RS04615	COG0573	inorganic phosphate transmembrane transporter activity
GJS33_RS04620	COG0581	inorganic phosphate transmembrane transporter activity
GJS33_RS04635	COG0704	Plays a role in the regulation of phosphate uptake
GJS33_RS04645	COG0745	RESPONSE REGULATOR receiver
GJS33_RS04650	COG5002	protein histidine kinase activity
GJS33_RS04705	COG1072	(Pantothenic acid kinase))
GJS33_RS04710	COG2813	Specifically methylates the guanine in position
GJS33_RS04715	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GJS33_RS04730	COG1744	ABC transporter substrate-binding protein PnrA-like
GJS33_RS04735	COG3845	ABC transporter
GJS33_RS04740	COG4603	Belongs to the binding-protein-dependent transport system permease family
GJS33_RS04745	COG1079	Belongs to the binding-protein-dependent transport system permease family
GJS33_RS04750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJS33_RS04755	COG4684	Psort location CytoplasmicMembrane, score
GJS33_RS04760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GJS33_RS04780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GJS33_RS04785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GJS33_RS04790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GJS33_RS04790	COG1328	CTP reductase activity
GJS33_RS04795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GJS33_RS04810	COG0488	(ABC) transporter
GJS33_RS04820	COG1597	lipid kinase activity
GJS33_RS04825	COG1272	protein, Hemolysin III
GJS33_RS04835	COG2226	methyltransferase
GJS33_RS04860	COG1131	(ABC) transporter
GJS33_RS04895	COG1136	(ABC) transporter
GJS33_RS04900	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GJS33_RS04910	COG0758	DNA mediated transformation
GJS33_RS04915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GJS33_RS04930	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GJS33_RS04935	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GJS33_RS04955	COG2851	Citrate transporter
GJS33_RS04965	COG0511	ligase activity, forming carbon-carbon bonds
GJS33_RS04970	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GJS33_RS04975	COG3052	prosthetic group binding
GJS33_RS05010	COG1136	(ABC) transporter
GJS33_RS05015	COG0577	efflux transmembrane transporter activity
GJS33_RS05020	COG0745	RESPONSE REGULATOR receiver
GJS33_RS05025	COG5002	protein histidine kinase activity
GJS33_RS05030	COG4974	Belongs to the 'phage' integrase family
GJS33_RS05115	COG2815	serine threonine protein kinase
GJS33_RS05115	COG0515	serine threonine protein kinase
GJS33_RS05130	COG1396	sequence-specific DNA binding
GJS33_RS05190	COG2188	Transcriptional regulator
GJS33_RS05200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GJS33_RS05220	COG0803	Belongs to the bacterial solute-binding protein 9 family
GJS33_RS05225	COG0346	lactoylglutathione lyase activity
GJS33_RS05230	COG3764	Sortase (surface protein transpeptidase)
GJS33_RS05260	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GJS33_RS05265	COG1247	-acetyltransferase
GJS33_RS05270	COG0009	L-threonylcarbamoyladenylate synthase
GJS33_RS05275	COG2890	protein-(glutamine-N5) methyltransferase activity
GJS33_RS05290	COG1942	4-Oxalocrotonate Tautomerase
GJS33_RS05300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJS33_RS05310	COG1174	glycine betaine transport
GJS33_RS05325	COG4221	oxidoreductase activity
GJS33_RS05330	COG0280	phosphate acetyltransferase
GJS33_RS05335	COG0564	pseudouridine synthase activity
GJS33_RS05345	COG2357	RelA SpoT domain protein
GJS33_RS05360	COG1104	cysteine desulfurase activity
GJS33_RS05375	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GJS33_RS05385	COG0628	permease
GJS33_RS05405	COG1177	transmembrane transport
GJS33_RS05410	COG1176	ABC-type spermidine putrescine transport system, permease component I
GJS33_RS05420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GJS33_RS05425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GJS33_RS05440	COG0302	gtp cyclohydrolase
GJS33_RS05445	COG0285	dihydrofolate synthase activity
GJS33_RS05460	COG0726	polysaccharide deacetylase
GJS33_RS05485	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GJS33_RS05490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GJS33_RS05500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GJS33_RS05510	COG3425	synthase
GJS33_RS05540	COG1132	(ABC) transporter
GJS33_RS05545	COG1132	(ABC) transporter
GJS33_RS05550	COG0737	Belongs to the 5'-nucleotidase family
GJS33_RS05555	COG0242	peptide deformylase activity
GJS33_RS05560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GJS33_RS05575	COG0488	(ABC) transporter
GJS33_RS05595	COG1705	Flagellar rod assembly protein muramidase FlgJ
GJS33_RS05595	COG1388	LysM domain
GJS33_RS05600	COG0693	protein deglycase activity
GJS33_RS05615	COG1705	Flagellar rod assembly protein muramidase FlgJ
GJS33_RS05615	COG1388	LysM domain
GJS33_RS05620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJS33_RS05620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJS33_RS05620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJS33_RS05625	COG1105	Belongs to the carbohydrate kinase PfkB family
GJS33_RS05630	COG1349	DNA-binding transcription factor activity
GJS33_RS05655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GJS33_RS05670	COG1837	Belongs to the UPF0109 family
GJS33_RS05690	COG0577	efflux transmembrane transporter activity
GJS33_RS05695	COG1136	(ABC) transporter
GJS33_RS05700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJS33_RS05735	COG0564	pseudouridine synthase activity
GJS33_RS05750	COG5433	transposase activity
GJS33_RS05755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GJS33_RS05810	COG0539	negative regulation of cytoplasmic translation
GJS33_RS05830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GJS33_RS05845	COG0187	DNA topoisomerase II activity
GJS33_RS05860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GJS33_RS05870	COG0765	amino acid transport
GJS33_RS05875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJS33_RS05890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GJS33_RS05895	COG0284	orotidine-5'-phosphate decarboxylase activity
GJS33_RS05905	COG0583	DNA-binding transcription factor activity
GJS33_RS05970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJS33_RS05985	COG1840	ABC-type Fe3 transport system, periplasmic component
GJS33_RS05990	COG4753	response regulator
GJS33_RS05990	COG2207	Transcriptional regulator
GJS33_RS05995	COG2972	Histidine kinase
GJS33_RS06000	COG3716	PTS system mannose fructose sorbose family IID component
GJS33_RS06005	COG3715	PTS system
GJS33_RS06025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJS33_RS06030	COG0481	GTPase activity
GJS33_RS06090	COG0647	UMP catabolic process
GJS33_RS06100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GJS33_RS06120	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GJS33_RS06125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJS33_RS06130	COG3442	glutamine amidotransferase
GJS33_RS06135	COG0095	Lipoate-protein ligase
GJS33_RS06145	COG0508	dehydrogenase complex catalyzes the overall conversion of
GJS33_RS06150	COG0022	dehydrogenase e1 component
GJS33_RS06150	COG0508	dehydrogenase complex catalyzes the overall conversion of
GJS33_RS06155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GJS33_RS06160	COG0488	(ABC) transporter
GJS33_RS06195	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GJS33_RS06200	COG0457	Tetratricopeptide repeat
GJS33_RS06205	COG0628	permease
GJS33_RS06210	COG1051	belongs to the nudix hydrolase family
GJS33_RS06215	COG1088	dTDP-glucose 4,6-dehydratase activity
GJS33_RS06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GJS33_RS06230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GJS33_RS06240	COG2384	SAM-dependent methyltransferase
GJS33_RS06245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GJS33_RS06265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GJS33_RS06265	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GJS33_RS06270	COG0300	oxidoreductase activity
GJS33_RS06280	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GJS33_RS06285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GJS33_RS06290	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GJS33_RS06305	COG0058	SHG alpha-glucan phosphorylase activity
GJS33_RS06310	COG1640	4-alpha-glucanotransferase
GJS33_RS06315	COG1609	Transcriptional regulator
GJS33_RS06325	COG1175	transmembrane transport
GJS33_RS06330	COG3833	ABC-type maltose transport systems, permease component
GJS33_RS06340	COG3833	ABC-type maltose transport systems, permease component
GJS33_RS06345	COG1175	transmembrane transport
GJS33_RS06355	COG0366	Alpha amylase catalytic
GJS33_RS06360	COG2182	Extracellular solute-binding protein
GJS33_RS06365	COG0657	acetylesterase activity
GJS33_RS06370	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GJS33_RS06380	COG1696	Membrane protein involved in D-alanine export
GJS33_RS06395	COG0556	nucleotide-excision repair
GJS33_RS06400	COG0765	amino acid transport
GJS33_RS06405	COG1126	abc transporter atp-binding protein
GJS33_RS06410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJS33_RS06420	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJS33_RS06430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJS33_RS06430	COG3711	transcriptional antiterminator
GJS33_RS06440	COG2723	6-phospho-beta-galactosidase activity
GJS33_RS06465	COG2309	aminopeptidase activity
GJS33_RS06470	COG1187	pseudouridine synthase activity
GJS33_RS06480	COG2814	Major facilitator Superfamily
GJS33_RS06500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GJS33_RS06510	COG5492	domain, Protein
GJS33_RS06515	COG0800	Aldolase
GJS33_RS06530	COG1028	Short-chain dehydrogenase reductase Sdr
GJS33_RS06545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJS33_RS06550	COG3715	PTS system
GJS33_RS06555	COG3716	PTS system mannose fructose sorbose family IID component
GJS33_RS06560	COG1609	Transcriptional regulator
GJS33_RS06595	COG1078	dGTPase activity
GJS33_RS06635	COG1191	sigma factor activity
GJS33_RS06650	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GJS33_RS06655	COG1518	maintenance of DNA repeat elements
GJS33_RS06720	COG2814	Major facilitator Superfamily
GJS33_RS06730	COG4443	Transcriptional Coactivator p15 (PC4)
GJS33_RS06740	COG0826	peptidase U32
GJS33_RS06765	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GJS33_RS06780	COG3091	SprT-like family
GJS33_RS06785	COG2183	response to ionizing radiation
GJS33_RS06795	COG0704	Plays a role in the regulation of phosphate uptake
GJS33_RS06800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJS33_RS06810	COG0573	inorganic phosphate transmembrane transporter activity
GJS33_RS06815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GJS33_RS06820	COG5002	protein histidine kinase activity
GJS33_RS06825	COG0745	RESPONSE REGULATOR receiver
GJS33_RS06830	COG0701	Predicted permease
GJS33_RS06835	COG3689	TIGRFAM TIGR03943 family protein
GJS33_RS06845	COG1263	PTS System
GJS33_RS06845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJS33_RS06845	COG2190	(PTS) system
GJS33_RS06850	COG3711	transcriptional antiterminator
GJS33_RS06855	COG0552	protein localization to endoplasmic reticulum
GJS33_RS06860	COG0561	phosphatase activity
GJS33_RS06865	COG0561	phosphatase activity
GJS33_RS06920	COG1028	Short-chain dehydrogenase reductase Sdr
GJS33_RS06925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GJS33_RS06945	COG1136	(ABC) transporter
GJS33_RS06975	COG1196	nuclear chromosome segregation
GJS33_RS06980	COG0571	ribonuclease III activity
GJS33_RS06995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GJS33_RS07000	COG5002	protein histidine kinase activity
GJS33_RS07005	COG0745	RESPONSE REGULATOR receiver
GJS33_RS07040	COG4555	ABC transporter
GJS33_RS07055	COG1131	(ABC) transporter
GJS33_RS07085	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GJS33_RS07090	COG0438	transferase activity, transferring glycosyl groups
GJS33_RS07105	COG1609	Transcriptional regulator
GJS33_RS07110	COG0006	proline dipeptidase activity
GJS33_RS07115	COG2274	protein secretion by the type I secretion system
GJS33_RS07130	COG0463	Glycosyl transferase, family 2
GJS33_RS07140	COG0557	exoribonuclease II activity
GJS33_RS07150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GJS33_RS07185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJS33_RS07190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJS33_RS07195	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJS33_RS07200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJS33_RS07210	COG1940	carbohydrate kinase activity
GJS33_RS07225	COG2610	gluconate transmembrane transporter activity
GJS33_RS07230	COG1028	Short-chain dehydrogenase reductase Sdr
GJS33_RS07240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GJS33_RS07245	COG0183	Belongs to the thiolase family
GJS33_RS07250	COG0583	DNA-binding transcription factor activity
GJS33_RS07260	COG1131	(ABC) transporter
GJS33_RS07275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GJS33_RS07290	COG1573	uracil-dna glycosylase
GJS33_RS07295	COG1702	phosphate starvation-inducible protein PhoH
GJS33_RS07330	COG0444	Belongs to the ABC transporter superfamily
GJS33_RS07335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJS33_RS07340	COG0601	transmembrane transport
GJS33_RS07345	COG0747	negative chemotaxis
GJS33_RS07420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GJS33_RS07440	COG0673	inositol 2-dehydrogenase activity
GJS33_RS07450	COG1028	Short-chain dehydrogenase reductase Sdr
GJS33_RS07465	COG1376	ErfK ybiS ycfS ynhG family protein
GJS33_RS07475	COG3586	endonuclease activity
GJS33_RS07480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GJS33_RS07505	COG5433	transposase activity
GJS33_RS07510	COG1605	Chorismate mutase
GJS33_RS07510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GJS33_RS07515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GJS33_RS07530	COG3250	beta-galactosidase activity
GJS33_RS07535	COG4753	response regulator
GJS33_RS07535	COG2207	Transcriptional regulator
GJS33_RS07540	COG2972	Histidine kinase
GJS33_RS07550	COG1653	transport
GJS33_RS07555	COG0395	ABC-type sugar transport system, permease component
GJS33_RS07560	COG1175	transmembrane transport
GJS33_RS07565	COG1940	carbohydrate kinase activity
GJS33_RS07575	COG2723	6-phospho-beta-galactosidase activity
GJS33_RS07585	COG2188	Transcriptional regulator
GJS33_RS07595	COG0383	alpha-mannosidase activity
GJS33_RS07600	COG1136	(ABC) transporter
GJS33_RS07660	COG2274	protein secretion by the type I secretion system
GJS33_RS07675	COG3290	protein histidine kinase activity
GJS33_RS07785	COG1040	competence protein
GJS33_RS07790	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GJS33_RS07795	COG1739	Uncharacterized protein family UPF0029
GJS33_RS07805	COG1098	S1 RNA binding domain
GJS33_RS07815	COG2197	response regulator
GJS33_RS07820	COG4585	Histidine kinase
GJS33_RS07830	COG0515	serine threonine protein kinase
GJS33_RS07830	COG2815	serine threonine protein kinase
GJS33_RS07840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GJS33_RS07840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GJS33_RS07845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GJS33_RS07850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GJS33_RS07870	COG1854	S-ribosylhomocysteine lyase activity
GJS33_RS07880	COG0116	Belongs to the methyltransferase superfamily
GJS33_RS07905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJS33_RS07910	COG3579	cysteine-type endopeptidase activity
GJS33_RS07920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GJS33_RS07925	COG1113	amino acid transport
GJS33_RS07930	COG0492	ferredoxin-NADP+ reductase activity
GJS33_RS07940	COG1126	abc transporter atp-binding protein
GJS33_RS07950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJS33_RS07960	COG0513	Belongs to the DEAD box helicase family
GJS33_RS07970	COG0768	penicillin binding
GJS33_RS08010	COG1131	(ABC) transporter
GJS33_RS08075	COG1774	PSP1 C-terminal conserved region
GJS33_RS08080	COG0470	DNA polymerase III
GJS33_RS08085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GJS33_RS08110	COG2244	polysaccharide biosynthetic process
GJS33_RS08120	COG1120	ATPase activity
GJS33_RS08125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GJS33_RS08130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJS33_RS08135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJS33_RS08150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GJS33_RS08155	COG1253	flavin adenine dinucleotide binding
GJS33_RS08160	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GJS33_RS08165	COG3231	kanamycin kinase activity
GJS33_RS08170	COG1242	4 iron, 4 sulfur cluster binding
GJS33_RS08175	COG0671	phosphoesterase, PA-phosphatase related
GJS33_RS08180	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GJS33_RS08245	COG1187	pseudouridine synthase activity
GJS33_RS08260	COG0582	viral genome integration into host DNA
GJS33_RS08300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJS33_RS08305	COG1254	Belongs to the acylphosphatase family
GJS33_RS08320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GJS33_RS08330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GJS33_RS08350	COG1484	DNA-dependent DNA replication
GJS33_RS08365	COG5002	protein histidine kinase activity
GJS33_RS08370	COG0745	RESPONSE REGULATOR receiver
GJS33_RS08385	COG1704	LemA family
GJS33_RS08395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GJS33_RS08400	COG0569	domain protein
GJS33_RS08410	COG1114	Component of the transport system for branched-chain amino acids
GJS33_RS08425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJS33_RS08430	COG1464	Belongs to the NlpA lipoprotein family
GJS33_RS08435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJS33_RS08445	COG0789	Transcriptional regulator
GJS33_RS08455	COG2226	methyltransferase
GJS33_RS08460	COG0799	negative regulation of ribosome biogenesis
GJS33_RS08465	COG1713	HD superfamily hydrolase involved in NAD metabolism
GJS33_RS08470	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GJS33_RS08475	COG1534	Rna-binding protein
GJS33_RS08480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GJS33_RS08485	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GJS33_RS08600	COG0444	Belongs to the ABC transporter superfamily
GJS33_RS08605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJS33_RS08610	COG0601	transmembrane transport
GJS33_RS08615	COG4166	transmembrane transport
GJS33_RS08620	COG1686	Belongs to the peptidase S11 family
GJS33_RS08625	COG1686	Belongs to the peptidase S11 family
GJS33_RS08635	COG0719	Fe-S assembly protein
GJS33_RS08645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GJS33_RS08650	COG0719	Fe-S assembly protein
GJS33_RS08660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GJS33_RS08675	COG0765	amino acid transport
GJS33_RS08680	COG1126	abc transporter atp-binding protein
GJS33_RS08715	COG0191	fructose-bisphosphate aldolase activity
GJS33_RS08730	COG0504	CTP synthase activity
GJS33_RS08745	COG0366	Alpha amylase catalytic
GJS33_RS08750	COG0668	transmembrane transport
GJS33_RS08760	COG4720	Psort location CytoplasmicMembrane, score
GJS33_RS08765	COG0352	thiamine-phosphate diphosphorylase activity
GJS33_RS08765	COG0351	phosphomethylpyrimidine kinase
GJS33_RS08775	COG0527	aspartate kinase activity
GJS33_RS08790	COG5433	transposase activity
GJS33_RS08830	COG0803	Belongs to the bacterial solute-binding protein 9 family
GJS33_RS08840	COG1597	lipid kinase activity
GJS33_RS08845	COG1609	Transcriptional regulator
GJS33_RS08850	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GJS33_RS08855	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GJS33_RS08860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJS33_RS08865	COG2017	converts alpha-aldose to the beta-anomer
GJS33_RS08870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GJS33_RS08875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GJS33_RS08890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJS33_RS08900	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GJS33_RS08910	COG1045	serine acetyltransferase
GJS33_RS08940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GJS33_RS08945	COG1846	Transcriptional regulator
GJS33_RS08960	COG0442	prolyl-tRNA aminoacylation
GJS33_RS08970	COG4589	Belongs to the CDS family
GJS33_RS08980	COG1862	Preprotein translocase
GJS33_RS09000	COG3842	ATPase activity
GJS33_RS09045	COG2190	(PTS) system
GJS33_RS09045	COG1263	PTS System
GJS33_RS09045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJS33_RS09050	COG1609	Transcriptional regulator
GJS33_RS09055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GJS33_RS09090	COG0512	Glutamine amidotransferase of anthranilate synthase
GJS33_RS09095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GJS33_RS09110	COG1396	sequence-specific DNA binding
GJS33_RS09165	COG1882	Formate acetyltransferase
GJS33_RS09170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJS33_RS09175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJS33_RS09180	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJS33_RS09195	COG1349	DNA-binding transcription factor activity
GJS33_RS09200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GJS33_RS09240	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GJS33_RS09245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GJS33_RS09250	COG1428	Deoxynucleoside kinase
GJS33_RS09265	COG4120	Belongs to the binding-protein-dependent transport system permease family
GJS33_RS09290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJS33_RS09295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJS33_RS09305	COG1363	Peptidase, m42
GJS33_RS09310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GJS33_RS09335	COG3022	response to hydroperoxide
GJS33_RS09340	COG0602	queuosine metabolic process
GJS33_RS09355	COG1328	CTP reductase activity
GJS33_RS09355	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GJS33_RS09380	COG1393	Belongs to the ArsC family
GJS33_RS09410	COG0519	Catalyzes the synthesis of GMP from XMP
GJS33_RS09415	COG0632	four-way junction helicase activity
GJS33_RS09420	COG2814	Major facilitator Superfamily
GJS33_RS09440	COG1438	arginine binding
GJS33_RS09445	COG0018	arginyl-trna synthetase
GJS33_RS09450	COG0488	(ABC) transporter
GJS33_RS09455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJS33_RS09460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJS33_RS09465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJS33_RS09470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GJS33_RS09480	COG1131	(ABC) transporter
GJS33_RS09500	COG0124	histidyl-tRNA synthetase
GJS33_RS09515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GJS33_RS09540	COG2197	response regulator
GJS33_RS09555	COG0577	efflux transmembrane transporter activity
GJS33_RS09555	COG1136	(ABC) transporter
GJS33_RS09575	COG0494	nUDIX hydrolase
GJS33_RS09595	COG1511	domain protein
GJS33_RS09615	COG0305	Participates in initiation and elongation during chromosome replication
GJS33_RS09635	COG2816	NAD+ diphosphatase activity
GJS33_RS09650	COG1760	l-serine dehydratase
GJS33_RS09655	COG1760	l-serine dehydratase
GJS33_RS09685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GJS33_RS09695	COG0612	Peptidase, M16
GJS33_RS09705	COG2501	S4 domain
GJS33_RS09740	COG0516	GMP reductase activity
GJS33_RS09740	COG0517	IMP dehydrogenase activity
GJS33_RS09750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJS33_RS09755	COG0488	(ABC) transporter
GJS33_RS09785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJS33_RS09790	COG1475	DNA binding