locus-tag	class	description
KCL43_RS00010	COG0592	DNA-directed DNA polymerase activity
KCL43_RS00025	COG0012	GTP binding
KCL43_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
KCL43_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCL43_RS00040	COG2244	polysaccharide biosynthetic process
KCL43_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KCL43_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCL43_RS00080	COG0531	amino acid
KCL43_RS00200	COG3942	CHAP domain
KCL43_RS00215	COG0416	fatty acid biosynthetic process
KCL43_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCL43_RS00245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCL43_RS00260	COG0151	Belongs to the GarS family
KCL43_RS00265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KCL43_RS00285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCL43_RS00305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCL43_RS00320	COG1012	belongs to the aldehyde dehydrogenase family
KCL43_RS00320	COG1454	alcohol dehydrogenase
KCL43_RS00325	COG1063	alcohol dehydrogenase
KCL43_RS00330	COG1064	alcohol dehydrogenase
KCL43_RS00335	COG1132	(ABC) transporter
KCL43_RS00340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KCL43_RS00350	COG1396	sequence-specific DNA binding
KCL43_RS00355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KCL43_RS00365	COG0051	transcription antitermination factor activity, RNA binding
KCL43_RS00380	COG0089	rRNA binding
KCL43_RS00470	COG0201	protein transport
KCL43_RS00505	COG0203	ribosomal protein L17
KCL43_RS00625	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KCL43_RS00640	COG1121	(ABC) transporter
KCL43_RS00645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KCL43_RS00655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCL43_RS00655	COG4499	WXG100 protein secretion system (Wss), protein YukC
KCL43_RS00665	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCL43_RS00705	COG1136	(ABC) transporter
KCL43_RS00710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCL43_RS00715	COG1459	type II secretion system
KCL43_RS00720	COG4537	Required for transformation and DNA binding
KCL43_RS00765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCL43_RS00780	COG3959	Transketolase, thiamine diphosphate binding domain
KCL43_RS00785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCL43_RS00790	COG3590	peptidase
KCL43_RS00795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCL43_RS00820	COG0450	alkyl hydroperoxide reductase
KCL43_RS00835	COG4463	regulation of RNA biosynthetic process
KCL43_RS00890	COG1051	belongs to the nudix hydrolase family
KCL43_RS00915	COG1116	anion transmembrane transporter activity
KCL43_RS00935	COG0564	pseudouridine synthase activity
KCL43_RS00955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCL43_RS00995	COG3037	sugar-specific permease SgaT UlaA
KCL43_RS01015	COG3623	hexulose-6-phosphate isomerase
KCL43_RS01040	COG3448	diguanylate cyclase activity
KCL43_RS01040	COG4175	Glycine betaine
KCL43_RS01050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCL43_RS01050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCL43_RS01055	COG1832	CoA-binding protein
KCL43_RS01080	COG0343	queuine tRNA-ribosyltransferase activity
KCL43_RS01110	COG1268	BioY protein
KCL43_RS01115	COG1234	tRNA 3'-trailer cleavage
KCL43_RS01130	COG5433	transposase activity
KCL43_RS01145	COG1215	transferase activity, transferring glycosyl groups
KCL43_RS01175	COG3711	transcriptional antiterminator
KCL43_RS01175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCL43_RS01185	COG3730	PTS system glucitol sorbitol-specific
KCL43_RS01190	COG3732	PTS system glucitol sorbitol-specific
KCL43_RS01220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCL43_RS01225	COG0705	Rhomboid family
KCL43_RS01225	COG0457	Tetratricopeptide repeat
KCL43_RS01245	COG1132	(ABC) transporter
KCL43_RS01250	COG1132	(ABC) transporter
KCL43_RS01260	COG0756	dUTP diphosphatase activity
KCL43_RS01315	COG1847	R3H domain protein
KCL43_RS01355	COG2190	(PTS) system
KCL43_RS01355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCL43_RS01355	COG1263	PTS System
KCL43_RS01360	COG2190	(PTS) system
KCL43_RS01360	COG1263	PTS System
KCL43_RS01360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCL43_RS01385	COG1175	transmembrane transport
KCL43_RS01390	COG0395	ABC-type sugar transport system, permease component
KCL43_RS01395	COG2731	YhcH YjgK YiaL family protein
KCL43_RS01405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCL43_RS01415	COG3458	cephalosporin-C deacetylase activity
KCL43_RS01420	COG1737	Transcriptional regulator
KCL43_RS01425	COG0084	hydrolase, TatD family'
KCL43_RS01450	COG1564	THIamine pyrophosphokinase
KCL43_RS01465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCL43_RS01495	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KCL43_RS01510	COG0789	Transcriptional regulator
KCL43_RS01515	COG0174	glutamine synthetase
KCL43_RS01520	COG4166	transmembrane transport
KCL43_RS01525	COG0601	transmembrane transport
KCL43_RS01530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCL43_RS01535	COG0444	Belongs to the ABC transporter superfamily
KCL43_RS01540	COG4608	Belongs to the ABC transporter superfamily
KCL43_RS01555	COG1214	PFAM Peptidase M22, glycoprotease
KCL43_RS01570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KCL43_RS01585	COG2081	HI0933 family
KCL43_RS01600	COG0789	Transcriptional regulator
KCL43_RS01605	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCL43_RS01620	COG5002	protein histidine kinase activity
KCL43_RS01660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCL43_RS01665	COG2814	Major facilitator Superfamily
KCL43_RS01675	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KCL43_RS01685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KCL43_RS01695	COG1882	Formate acetyltransferase
KCL43_RS01710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KCL43_RS01715	COG0681	Belongs to the peptidase S26 family
KCL43_RS01730	COG1286	toxin biosynthetic process
KCL43_RS01735	COG1193	negative regulation of DNA recombination
KCL43_RS01740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCL43_RS01745	COG3118	belongs to the thioredoxin family
KCL43_RS01760	COG1194	a g-specific adenine glycosylase
KCL43_RS01800	COG0006	proline dipeptidase activity
KCL43_RS01805	COG2131	deaminase
KCL43_RS01845	COG1609	Transcriptional regulator
KCL43_RS01850	COG1621	beta-fructofuranosidase activity
KCL43_RS01855	COG2190	(PTS) system
KCL43_RS01855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCL43_RS01855	COG1263	PTS System
KCL43_RS01865	COG1940	carbohydrate kinase activity
KCL43_RS01870	COG1482	cell wall glycoprotein biosynthetic process
KCL43_RS01875	COG0653	protein targeting
KCL43_RS01890	COG3942	CHAP domain
KCL43_RS01890	COG1388	LysM domain
KCL43_RS01915	COG1120	ATPase activity
KCL43_RS01920	COG4988	ABC transporter
KCL43_RS01925	COG1132	(ABC) transporter
KCL43_RS01940	COG1129	ABC transporter
KCL43_RS01945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCL43_RS01950	COG0252	asparaginase activity
KCL43_RS01955	COG0561	phosphatase activity
KCL43_RS01965	COG0436	Aminotransferase
KCL43_RS01970	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KCL43_RS01975	COG1335	isochorismatase
KCL43_RS01990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCL43_RS01995	COG0697	spore germination
KCL43_RS02000	COG2261	transglycosylase associated protein
KCL43_RS02010	COG3830	Belongs to the UPF0237 family
KCL43_RS02020	COG0588	phosphoglycerate mutase activity
KCL43_RS02025	COG1876	peptidase activity
KCL43_RS02035	COG1420	regulation of RNA biosynthetic process
KCL43_RS02050	COG0484	heat shock protein binding
KCL43_RS02055	COG1024	Enoyl-CoA hydratase
KCL43_RS02065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCL43_RS02075	COG2070	2-Nitropropane dioxygenase
KCL43_RS02080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KCL43_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
KCL43_RS02090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCL43_RS02105	COG0439	Biotin carboxylase
KCL43_RS02110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCL43_RS02135	COG3716	PTS system mannose fructose sorbose family IID component
KCL43_RS02140	COG3715	PTS system
KCL43_RS02155	COG0561	phosphatase activity
KCL43_RS02160	COG2252	PERMEase
KCL43_RS02165	COG0802	atpase or kinase
KCL43_RS02175	COG1316	TRANSCRIPTIONal
KCL43_RS02185	COG0537	adenosine 5'-monophosphoramidase activity
KCL43_RS02195	COG1131	(ABC) transporter
KCL43_RS02200	COG4473	ABC transporter
KCL43_RS02225	COG4974	Belongs to the 'phage' integrase family
KCL43_RS02240	COG1396	sequence-specific DNA binding
KCL43_RS02335	COG1783	phage Terminase large subunit
KCL43_RS02490	COG0195	Participates in both transcription termination and antitermination
KCL43_RS02495	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KCL43_RS02525	COG2217	Heavy metal translocating P-type atpase
KCL43_RS02545	COG0698	ribose 5-phosphate isomerase
KCL43_RS02565	COG3711	transcriptional antiterminator
KCL43_RS02570	COG1447	Phosphotransferase system cellobiose-specific component IIA
KCL43_RS02575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCL43_RS02575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCL43_RS02580	COG2723	6-phospho-beta-galactosidase activity
KCL43_RS02590	COG2860	membrane
KCL43_RS02595	COG0561	phosphatase activity
KCL43_RS02610	COG1609	Transcriptional regulator
KCL43_RS02615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCL43_RS02620	COG1869	D-ribose catabolic process
KCL43_RS02630	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCL43_RS02635	COG1879	ABC-type sugar transport system periplasmic component
KCL43_RS02645	COG1283	sodium-dependent phosphate transmembrane transporter activity
KCL43_RS02655	COG0656	L-ascorbic acid biosynthetic process
KCL43_RS02665	COG1755	Isoprenylcysteine carboxyl methyltransferase
KCL43_RS02715	COG1131	(ABC) transporter
KCL43_RS02760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KCL43_RS02765	COG1393	Belongs to the ArsC family
KCL43_RS02780	COG0708	Exodeoxyribonuclease III
KCL43_RS02840	COG2274	protein secretion by the type I secretion system
KCL43_RS02845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCL43_RS02870	COG1114	Component of the transport system for branched-chain amino acids
KCL43_RS03005	COG1518	maintenance of DNA repeat elements
KCL43_RS03010	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCL43_RS03015	COG0785	Cytochrome C biogenesis protein
KCL43_RS03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCL43_RS03030	COG2207	Transcriptional regulator
KCL43_RS03030	COG4753	response regulator
KCL43_RS03035	COG2972	Histidine kinase
KCL43_RS03040	COG2315	Protein conserved in bacteria
KCL43_RS03075	COG0454	-acetyltransferase
KCL43_RS03085	COG1288	antiporter activity
KCL43_RS03090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCL43_RS03095	COG0549	Belongs to the carbamate kinase family
KCL43_RS03105	COG0742	ribosomal rna small subunit methyltransferase
KCL43_RS03115	COG3480	Lon protease (S16) C-terminal proteolytic domain
KCL43_RS03120	COG4470	Protein conserved in bacteria
KCL43_RS03135	COG0783	Belongs to the Dps family
KCL43_RS03140	COG4483	Protein conserved in bacteria
KCL43_RS03145	COG1940	carbohydrate kinase activity
KCL43_RS03150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCL43_RS03155	COG1217	gtp-binding protein TYPA
KCL43_RS03180	COG0849	cell division
KCL43_RS03190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCL43_RS03210	COG3599	regulation of cell shape
KCL43_RS03225	COG0494	nUDIX hydrolase
KCL43_RS03230	COG0542	response to heat
KCL43_RS03235	COG4703	Protein of unknown function (DUF1797)
KCL43_RS03245	COG0765	amino acid transport
KCL43_RS03250	COG1126	abc transporter atp-binding protein
KCL43_RS03255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCL43_RS03265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KCL43_RS03285	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KCL43_RS03290	COG1438	arginine binding
KCL43_RS03295	COG0497	DNA recombination
KCL43_RS03310	COG2755	lipolytic protein G-D-S-L family
KCL43_RS03315	COG4698	Protein conserved in bacteria
KCL43_RS03335	COG1396	sequence-specific DNA binding
KCL43_RS03345	COG0167	dihydroorotate dehydrogenase activity
KCL43_RS03355	COG1827	regulation of RNA biosynthetic process
KCL43_RS03365	COG2116	formate transmembrane transporter activity
KCL43_RS03370	COG0768	penicillin binding
KCL43_RS03385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCL43_RS03405	COG0513	Belongs to the DEAD box helicase family
KCL43_RS03420	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KCL43_RS03425	COG0204	Acyl-transferase
KCL43_RS03430	COG1555	photosystem II stabilization
KCL43_RS03435	COG0658	competence protein
KCL43_RS03435	COG2333	competence protein COMEC
KCL43_RS03475	COG1187	pseudouridine synthase activity
KCL43_RS03500	COG0546	phosphoglycolate phosphatase activity
KCL43_RS03505	COG4122	O-methyltransferase activity
KCL43_RS03510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KCL43_RS03525	COG0726	polysaccharide deacetylase
KCL43_RS03530	COG0513	Belongs to the DEAD box helicase family
KCL43_RS03550	COG1956	GAF domain-containing protein
KCL43_RS03555	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCL43_RS03565	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KCL43_RS03565	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KCL43_RS03590	COG2211	Major facilitator Superfamily
KCL43_RS03600	COG3250	beta-galactosidase activity
KCL43_RS03605	COG2186	Transcriptional regulator
KCL43_RS03610	COG0800	Aldolase
KCL43_RS03625	COG1028	Short-chain dehydrogenase reductase Sdr
KCL43_RS03645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCL43_RS03650	COG4109	DRTGG domain
KCL43_RS03655	COG0024	Methionine aminopeptidase
KCL43_RS03665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KCL43_RS03675	COG1316	TRANSCRIPTIONal
KCL43_RS03680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCL43_RS03735	COG1373	ATPase (AAA superfamily
KCL43_RS03745	COG0588	phosphoglycerate mutase activity
KCL43_RS03755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCL43_RS03760	COG3859	Proton-coupled thiamine transporter YuaJ
KCL43_RS03785	COG0386	Belongs to the glutathione peroxidase family
KCL43_RS03790	COG1164	Oligoendopeptidase f
KCL43_RS03800	COG0772	Belongs to the SEDS family
KCL43_RS03810	COG1131	(ABC) transporter
KCL43_RS03825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KCL43_RS03840	COG2884	Cell division ATP-binding protein ftsE
KCL43_RS03845	COG2177	Part of the ABC transporter FtsEX involved in
KCL43_RS03855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCL43_RS03855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCL43_RS03855	COG1199	ATP-dependent helicase activity
KCL43_RS03855	COG1199	ATP-dependent helicase activity
KCL43_RS03865	COG0436	Aminotransferase
KCL43_RS03870	COG0017	Asparaginyl-tRNA synthetase
KCL43_RS03905	COG2188	Transcriptional regulator
KCL43_RS03910	COG2222	sugar isomerase
KCL43_RS03915	COG3684	Belongs to the aldolase LacD family
KCL43_RS03920	COG2188	Transcriptional regulator
KCL43_RS03930	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCL43_RS03930	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCL43_RS03935	COG3715	PTS system
KCL43_RS03955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KCL43_RS03960	COG2153	protein acetylation
KCL43_RS03965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KCL43_RS03970	COG0716	FMN binding
KCL43_RS03980	COG0038	chloride channel
KCL43_RS04000	COG1476	TRANSCRIPTIONal
KCL43_RS04020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCL43_RS04025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KCL43_RS04030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCL43_RS04040	COG1012	belongs to the aldehyde dehydrogenase family
KCL43_RS04045	COG0772	Belongs to the SEDS family
KCL43_RS04095	COG4708	membrane
KCL43_RS04105	COG1597	lipid kinase activity
KCL43_RS04110	COG1523	belongs to the glycosyl hydrolase 13 family
KCL43_RS04115	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCL43_RS04120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCL43_RS04125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCL43_RS04135	COG0058	SHG alpha-glucan phosphorylase activity
KCL43_RS04210	COG0577	efflux transmembrane transporter activity
KCL43_RS04225	COG1309	transcriptional regulator
KCL43_RS04275	COG1523	belongs to the glycosyl hydrolase 13 family
KCL43_RS04280	COG1595	DNA-templated transcription, initiation
KCL43_RS04330	COG1074	ATP-dependent DNA helicase activity
KCL43_RS04335	COG0436	Aminotransferase
KCL43_RS04340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCL43_RS04350	COG1970	mechanosensitive ion channel activity
KCL43_RS04355	COG0358	DNA primase activity
KCL43_RS04360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCL43_RS04365	COG2151	metal-sulfur cluster biosynthetic enzyme
KCL43_RS04370	COG1091	dTDP-4-dehydrorhamnose reductase activity
KCL43_RS04380	COG0463	Glycosyl transferase, family 2
KCL43_RS04405	COG0463	Glycosyl transferase, family 2
KCL43_RS04425	COG0297	glycogen (starch) synthase activity
KCL43_RS04430	COG1368	sulfuric ester hydrolase activity
KCL43_RS04435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KCL43_RS04485	COG1368	sulfuric ester hydrolase activity
KCL43_RS04490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KCL43_RS04505	COG3679	Belongs to the UPF0342 family
KCL43_RS04510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCL43_RS04520	COG1104	cysteine desulfurase activity
KCL43_RS04560	COG1131	(ABC) transporter
KCL43_RS04565	COG1725	Transcriptional regulator
KCL43_RS04580	COG0469	pyruvate kinase activity
KCL43_RS04595	COG2824	Alkylphosphonate utilization operon protein PhnA
KCL43_RS04600	COG0765	amino acid transport
KCL43_RS04605	COG1126	abc transporter atp-binding protein
KCL43_RS04610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCL43_RS04615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCL43_RS04620	COG1115	amino acid carrier protein
KCL43_RS04670	COG4591	ABC-type transport system involved in lipoprotein release permease component
KCL43_RS04670	COG1136	(ABC) transporter
KCL43_RS04700	COG0196	riboflavin kinase activity
KCL43_RS04715	COG0483	inositol monophosphate 1-phosphatase activity
KCL43_RS04720	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KCL43_RS04720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCL43_RS04730	COG0573	inorganic phosphate transmembrane transporter activity
KCL43_RS04735	COG0581	inorganic phosphate transmembrane transporter activity
KCL43_RS04750	COG0704	Plays a role in the regulation of phosphate uptake
KCL43_RS04760	COG0745	RESPONSE REGULATOR receiver
KCL43_RS04765	COG5002	protein histidine kinase activity
KCL43_RS04845	COG1072	(Pantothenic acid kinase))
KCL43_RS04850	COG2813	Specifically methylates the guanine in position
KCL43_RS04855	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KCL43_RS04870	COG1744	ABC transporter substrate-binding protein PnrA-like
KCL43_RS04875	COG3845	ABC transporter
KCL43_RS04880	COG4603	Belongs to the binding-protein-dependent transport system permease family
KCL43_RS04885	COG1079	Belongs to the binding-protein-dependent transport system permease family
KCL43_RS04890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCL43_RS04895	COG4684	Psort location CytoplasmicMembrane, score
KCL43_RS04900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCL43_RS04920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCL43_RS04925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCL43_RS04930	COG1328	CTP reductase activity
KCL43_RS04930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCL43_RS04935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCL43_RS04950	COG0488	(ABC) transporter
KCL43_RS04960	COG1597	lipid kinase activity
KCL43_RS04965	COG1272	protein, Hemolysin III
KCL43_RS04975	COG2226	methyltransferase
KCL43_RS05000	COG1131	(ABC) transporter
KCL43_RS05025	COG1136	(ABC) transporter
KCL43_RS05025	COG0577	efflux transmembrane transporter activity
KCL43_RS05030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCL43_RS05040	COG0758	DNA mediated transformation
KCL43_RS05045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCL43_RS05060	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KCL43_RS05065	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KCL43_RS05085	COG2851	Citrate transporter
KCL43_RS05095	COG0511	ligase activity, forming carbon-carbon bonds
KCL43_RS05100	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KCL43_RS05105	COG3052	prosthetic group binding
KCL43_RS05135	COG1136	(ABC) transporter
KCL43_RS05140	COG0577	efflux transmembrane transporter activity
KCL43_RS05145	COG0745	RESPONSE REGULATOR receiver
KCL43_RS05150	COG5002	protein histidine kinase activity
KCL43_RS05155	COG4974	Belongs to the 'phage' integrase family
KCL43_RS05165	COG1396	sequence-specific DNA binding
KCL43_RS05170	COG0582	viral genome integration into host DNA
KCL43_RS05195	COG2188	Transcriptional regulator
KCL43_RS05205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCL43_RS05225	COG0803	Belongs to the bacterial solute-binding protein 9 family
KCL43_RS05230	COG0346	lactoylglutathione lyase activity
KCL43_RS05235	COG3764	Sortase (surface protein transpeptidase)
KCL43_RS05265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCL43_RS05270	COG1247	-acetyltransferase
KCL43_RS05275	COG0009	L-threonylcarbamoyladenylate synthase
KCL43_RS05280	COG2890	protein-(glutamine-N5) methyltransferase activity
KCL43_RS05295	COG1942	4-Oxalocrotonate Tautomerase
KCL43_RS05305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCL43_RS05315	COG1174	glycine betaine transport
KCL43_RS05330	COG4221	oxidoreductase activity
KCL43_RS05335	COG0280	phosphate acetyltransferase
KCL43_RS05340	COG0564	pseudouridine synthase activity
KCL43_RS05350	COG2357	RelA SpoT domain protein
KCL43_RS05365	COG1104	cysteine desulfurase activity
KCL43_RS05380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KCL43_RS05390	COG0628	permease
KCL43_RS05410	COG1177	transmembrane transport
KCL43_RS05415	COG1176	ABC-type spermidine putrescine transport system, permease component I
KCL43_RS05425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KCL43_RS05430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCL43_RS05445	COG0302	gtp cyclohydrolase
KCL43_RS05450	COG0285	dihydrofolate synthase activity
KCL43_RS05460	COG0460	homoserine dehydrogenase
KCL43_RS05465	COG0726	polysaccharide deacetylase
KCL43_RS05475	COG0105	UTP biosynthetic process
KCL43_RS05490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KCL43_RS05495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCL43_RS05505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCL43_RS05515	COG3425	synthase
KCL43_RS05545	COG1132	(ABC) transporter
KCL43_RS05550	COG1132	(ABC) transporter
KCL43_RS05555	COG0737	Belongs to the 5'-nucleotidase family
KCL43_RS05560	COG0242	peptide deformylase activity
KCL43_RS05565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KCL43_RS05570	COG1132	(ABC) transporter
KCL43_RS05580	COG0488	(ABC) transporter
KCL43_RS05600	COG1705	Flagellar rod assembly protein muramidase FlgJ
KCL43_RS05600	COG1388	LysM domain
KCL43_RS05620	COG1476	TRANSCRIPTIONal
KCL43_RS05635	COG0693	protein deglycase activity
KCL43_RS05650	COG1705	Flagellar rod assembly protein muramidase FlgJ
KCL43_RS05650	COG1388	LysM domain
KCL43_RS05655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCL43_RS05655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCL43_RS05655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCL43_RS05660	COG1105	Belongs to the carbohydrate kinase PfkB family
KCL43_RS05665	COG1349	DNA-binding transcription factor activity
KCL43_RS05685	COG0336	Belongs to the RNA methyltransferase TrmD family
KCL43_RS05690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCL43_RS05710	COG1837	Belongs to the UPF0109 family
KCL43_RS05725	COG0577	efflux transmembrane transporter activity
KCL43_RS05730	COG1136	(ABC) transporter
KCL43_RS05735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCL43_RS05745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KCL43_RS05775	COG0564	pseudouridine synthase activity
KCL43_RS05790	COG5433	transposase activity
KCL43_RS05795	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KCL43_RS05855	COG0539	negative regulation of cytoplasmic translation
KCL43_RS05875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCL43_RS05890	COG0187	DNA topoisomerase II activity
KCL43_RS05905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCL43_RS05915	COG0765	amino acid transport
KCL43_RS05935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCL43_RS05940	COG0284	orotidine-5'-phosphate decarboxylase activity
KCL43_RS05950	COG0583	DNA-binding transcription factor activity
KCL43_RS05970	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCL43_RS06065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCL43_RS06085	COG2207	Transcriptional regulator
KCL43_RS06085	COG4753	response regulator
KCL43_RS06090	COG2972	Histidine kinase
KCL43_RS06095	COG3716	PTS system mannose fructose sorbose family IID component
KCL43_RS06100	COG3715	PTS system
KCL43_RS06125	COG0481	GTPase activity
KCL43_RS06190	COG0647	UMP catabolic process
KCL43_RS06200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KCL43_RS06220	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCL43_RS06225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCL43_RS06230	COG3442	glutamine amidotransferase
KCL43_RS06235	COG0095	Lipoate-protein ligase
KCL43_RS06245	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCL43_RS06250	COG0022	dehydrogenase e1 component
KCL43_RS06250	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCL43_RS06255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KCL43_RS06260	COG0488	(ABC) transporter
KCL43_RS06275	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KCL43_RS06290	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KCL43_RS06295	COG0457	Tetratricopeptide repeat
KCL43_RS06300	COG0628	permease
KCL43_RS06305	COG1051	belongs to the nudix hydrolase family
KCL43_RS06310	COG1088	dTDP-glucose 4,6-dehydratase activity
KCL43_RS06320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCL43_RS06325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCL43_RS06335	COG2384	SAM-dependent methyltransferase
KCL43_RS06340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCL43_RS06360	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KCL43_RS06360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KCL43_RS06365	COG0300	oxidoreductase activity
KCL43_RS06375	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KCL43_RS06380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCL43_RS06400	COG0058	SHG alpha-glucan phosphorylase activity
KCL43_RS06405	COG1640	4-alpha-glucanotransferase
KCL43_RS06410	COG1609	Transcriptional regulator
KCL43_RS06420	COG1175	transmembrane transport
KCL43_RS06425	COG3833	ABC-type maltose transport systems, permease component
KCL43_RS06435	COG3833	ABC-type maltose transport systems, permease component
KCL43_RS06440	COG1175	transmembrane transport
KCL43_RS06450	COG0366	Alpha amylase catalytic
KCL43_RS06455	COG2182	Extracellular solute-binding protein
KCL43_RS06460	COG0657	acetylesterase activity
KCL43_RS06465	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KCL43_RS06475	COG1696	Membrane protein involved in D-alanine export
KCL43_RS06490	COG0556	nucleotide-excision repair
KCL43_RS06495	COG0765	amino acid transport
KCL43_RS06500	COG1126	abc transporter atp-binding protein
KCL43_RS06510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCL43_RS06520	COG1447	Phosphotransferase system cellobiose-specific component IIA
KCL43_RS06530	COG3711	transcriptional antiterminator
KCL43_RS06530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCL43_RS06540	COG2723	6-phospho-beta-galactosidase activity
KCL43_RS06565	COG2309	aminopeptidase activity
KCL43_RS06570	COG1187	pseudouridine synthase activity
KCL43_RS06580	COG2814	Major facilitator Superfamily
KCL43_RS06615	COG5492	domain, Protein
KCL43_RS06620	COG0800	Aldolase
KCL43_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
KCL43_RS06650	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCL43_RS06655	COG3715	PTS system
KCL43_RS06660	COG3716	PTS system mannose fructose sorbose family IID component
KCL43_RS06665	COG1609	Transcriptional regulator
KCL43_RS06700	COG1078	dGTPase activity
KCL43_RS06740	COG1191	sigma factor activity
KCL43_RS06790	COG2814	Major facilitator Superfamily
KCL43_RS06805	COG4443	Transcriptional Coactivator p15 (PC4)
KCL43_RS06815	COG0826	peptidase U32
KCL43_RS06855	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCL43_RS06870	COG3091	SprT-like family
KCL43_RS06875	COG2183	response to ionizing radiation
KCL43_RS06885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KCL43_RS06895	COG0573	inorganic phosphate transmembrane transporter activity
KCL43_RS06900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCL43_RS06905	COG5002	protein histidine kinase activity
KCL43_RS06910	COG0745	RESPONSE REGULATOR receiver
KCL43_RS06920	COG0701	Predicted permease
KCL43_RS06925	COG3689	TIGRFAM TIGR03943 family protein
KCL43_RS06935	COG2190	(PTS) system
KCL43_RS06935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCL43_RS06935	COG1263	PTS System
KCL43_RS06940	COG3711	transcriptional antiterminator
KCL43_RS06945	COG0552	protein localization to endoplasmic reticulum
KCL43_RS06950	COG0561	phosphatase activity
KCL43_RS06955	COG0561	phosphatase activity
KCL43_RS06985	COG1196	nuclear chromosome segregation
KCL43_RS06990	COG0571	ribonuclease III activity
KCL43_RS07010	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KCL43_RS07015	COG5002	protein histidine kinase activity
KCL43_RS07020	COG0745	RESPONSE REGULATOR receiver
KCL43_RS07035	COG0183	Belongs to the thiolase family
KCL43_RS07055	COG4555	ABC transporter
KCL43_RS07070	COG1131	(ABC) transporter
KCL43_RS07100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCL43_RS07105	COG0438	transferase activity, transferring glycosyl groups
KCL43_RS07120	COG1609	Transcriptional regulator
KCL43_RS07125	COG0006	proline dipeptidase activity
KCL43_RS07130	COG2274	protein secretion by the type I secretion system
KCL43_RS07145	COG0463	Glycosyl transferase, family 2
KCL43_RS07150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KCL43_RS07155	COG0557	exoribonuclease II activity
KCL43_RS07165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KCL43_RS07200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCL43_RS07205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCL43_RS07210	COG1447	Phosphotransferase system cellobiose-specific component IIA
KCL43_RS07215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCL43_RS07225	COG1940	carbohydrate kinase activity
KCL43_RS07265	COG1136	(ABC) transporter
KCL43_RS07315	COG0613	PHP domain protein
KCL43_RS07320	COG0542	response to heat
KCL43_RS07325	COG1396	sequence-specific DNA binding
KCL43_RS07355	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KCL43_RS07375	COG1396	sequence-specific DNA binding
KCL43_RS07420	COG0583	DNA-binding transcription factor activity
KCL43_RS07450	COG1136	(ABC) transporter
KCL43_RS07455	COG1770	oligopeptidase
KCL43_RS07485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KCL43_RS07500	COG1573	uracil-dna glycosylase
KCL43_RS07505	COG1702	phosphate starvation-inducible protein PhoH
KCL43_RS07540	COG0444	Belongs to the ABC transporter superfamily
KCL43_RS07545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCL43_RS07550	COG0601	transmembrane transport
KCL43_RS07555	COG0747	negative chemotaxis
KCL43_RS07620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCL43_RS07640	COG0673	inositol 2-dehydrogenase activity
KCL43_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
KCL43_RS07670	COG1376	ErfK ybiS ycfS ynhG family protein
KCL43_RS07690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCL43_RS07710	COG1605	Chorismate mutase
KCL43_RS07710	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KCL43_RS07725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCL43_RS07730	COG3250	beta-galactosidase activity
KCL43_RS07735	COG4753	response regulator
KCL43_RS07735	COG2207	Transcriptional regulator
KCL43_RS07740	COG2972	Histidine kinase
KCL43_RS07750	COG1653	transport
KCL43_RS07755	COG0395	ABC-type sugar transport system, permease component
KCL43_RS07760	COG1175	transmembrane transport
KCL43_RS07765	COG1940	carbohydrate kinase activity
KCL43_RS07775	COG2723	6-phospho-beta-galactosidase activity
KCL43_RS07780	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KCL43_RS07780	COG3291	Pkd domain containing protein
KCL43_RS07795	COG0383	alpha-mannosidase activity
KCL43_RS07800	COG1136	(ABC) transporter
KCL43_RS07800	COG0577	efflux transmembrane transporter activity
KCL43_RS07855	COG2274	protein secretion by the type I secretion system
KCL43_RS07870	COG3290	protein histidine kinase activity
KCL43_RS07980	COG1040	competence protein
KCL43_RS08005	COG3969	phosphoadenosine phosphosulfate
KCL43_RS08010	COG1475	DNA binding
KCL43_RS08040	COG1705	Flagellar rod assembly protein muramidase FlgJ
KCL43_RS08135	COG0740	serine-type endopeptidase activity
KCL43_RS08170	COG0582	viral genome integration into host DNA
KCL43_RS08280	COG1739	Uncharacterized protein family UPF0029
KCL43_RS08290	COG1098	S1 RNA binding domain
KCL43_RS08300	COG2197	response regulator
KCL43_RS08305	COG4585	Histidine kinase
KCL43_RS08315	COG2815	serine threonine protein kinase
KCL43_RS08315	COG0515	serine threonine protein kinase
KCL43_RS08325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCL43_RS08325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCL43_RS08330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCL43_RS08335	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCL43_RS08355	COG1854	S-ribosylhomocysteine lyase activity
KCL43_RS08365	COG0116	Belongs to the methyltransferase superfamily
KCL43_RS08390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCL43_RS08395	COG3579	cysteine-type endopeptidase activity
KCL43_RS08405	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCL43_RS08410	COG1113	amino acid transport
KCL43_RS08420	COG0492	ferredoxin-NADP+ reductase activity
KCL43_RS08430	COG1126	abc transporter atp-binding protein
KCL43_RS08440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCL43_RS08450	COG0513	Belongs to the DEAD box helicase family
KCL43_RS08460	COG0768	penicillin binding
KCL43_RS08500	COG1131	(ABC) transporter
KCL43_RS08555	COG1774	PSP1 C-terminal conserved region
KCL43_RS08560	COG0470	DNA polymerase III
KCL43_RS08570	COG4471	UPF0298 protein
KCL43_RS08590	COG2244	polysaccharide biosynthetic process
KCL43_RS08600	COG1120	ATPase activity
KCL43_RS08605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KCL43_RS08610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCL43_RS08615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCL43_RS08625	COG1227	inorganic diphosphatase activity
KCL43_RS08630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCL43_RS08635	COG1253	flavin adenine dinucleotide binding
KCL43_RS08640	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KCL43_RS08650	COG1242	4 iron, 4 sulfur cluster binding
KCL43_RS08655	COG0671	phosphoesterase, PA-phosphatase related
KCL43_RS08660	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KCL43_RS08715	COG1187	pseudouridine synthase activity
KCL43_RS08725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCL43_RS08730	COG0582	viral genome integration into host DNA
KCL43_RS08770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCL43_RS08775	COG1254	Belongs to the acylphosphatase family
KCL43_RS08790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCL43_RS08820	COG1484	DNA-dependent DNA replication
KCL43_RS08835	COG5002	protein histidine kinase activity
KCL43_RS08840	COG0745	RESPONSE REGULATOR receiver
KCL43_RS08855	COG1704	LemA family
KCL43_RS08865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KCL43_RS08870	COG0569	domain protein
KCL43_RS08880	COG1114	Component of the transport system for branched-chain amino acids
KCL43_RS08895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCL43_RS08900	COG1464	Belongs to the NlpA lipoprotein family
KCL43_RS08905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCL43_RS08915	COG0789	Transcriptional regulator
KCL43_RS08925	COG2226	methyltransferase
KCL43_RS08930	COG0799	negative regulation of ribosome biogenesis
KCL43_RS08935	COG1713	HD superfamily hydrolase involved in NAD metabolism
KCL43_RS08940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCL43_RS08945	COG1534	Rna-binding protein
KCL43_RS08950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCL43_RS08955	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KCL43_RS09000	COG0444	Belongs to the ABC transporter superfamily
KCL43_RS09005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCL43_RS09010	COG0601	transmembrane transport
KCL43_RS09015	COG4166	transmembrane transport
KCL43_RS09020	COG1686	Belongs to the peptidase S11 family
KCL43_RS09025	COG1686	Belongs to the peptidase S11 family
KCL43_RS09035	COG0719	Fe-S assembly protein
KCL43_RS09045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCL43_RS09050	COG0719	Fe-S assembly protein
KCL43_RS09060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCL43_RS09070	COG1968	undecaprenyl-diphosphatase activity
KCL43_RS09075	COG0765	amino acid transport
KCL43_RS09080	COG1126	abc transporter atp-binding protein
KCL43_RS09115	COG0191	fructose-bisphosphate aldolase activity
KCL43_RS09145	COG0544	peptidyl-prolyl cis-trans isomerase activity
KCL43_RS09150	COG0366	Alpha amylase catalytic
KCL43_RS09155	COG0668	transmembrane transport
KCL43_RS09165	COG4720	Psort location CytoplasmicMembrane, score
KCL43_RS09170	COG0351	phosphomethylpyrimidine kinase
KCL43_RS09170	COG0352	thiamine-phosphate diphosphorylase activity
KCL43_RS09180	COG0527	aspartate kinase activity
KCL43_RS09290	COG0803	Belongs to the bacterial solute-binding protein 9 family
KCL43_RS09300	COG1597	lipid kinase activity
KCL43_RS09305	COG1609	Transcriptional regulator
KCL43_RS09310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCL43_RS09315	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KCL43_RS09320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KCL43_RS09325	COG2017	converts alpha-aldose to the beta-anomer
KCL43_RS09355	COG1674	ftsk spoiiie
KCL43_RS09390	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCL43_RS09405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCL43_RS09415	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KCL43_RS09425	COG1045	serine acetyltransferase
KCL43_RS09435	COG1185	polyribonucleotide nucleotidyltransferase activity
KCL43_RS09455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KCL43_RS09460	COG1846	Transcriptional regulator
KCL43_RS09475	COG0442	prolyl-tRNA aminoacylation
KCL43_RS09485	COG4589	Belongs to the CDS family
KCL43_RS09495	COG1862	Preprotein translocase
KCL43_RS09510	COG3842	ATPase activity
KCL43_RS09555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCL43_RS09555	COG2190	(PTS) system
KCL43_RS09555	COG1263	PTS System
KCL43_RS09560	COG1609	Transcriptional regulator
KCL43_RS09565	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KCL43_RS09570	COG2264	protein methyltransferase activity
KCL43_RS09595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCL43_RS09600	COG0512	Glutamine amidotransferase of anthranilate synthase
KCL43_RS09605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KCL43_RS09680	COG1882	Formate acetyltransferase
KCL43_RS09685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCL43_RS09690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KCL43_RS09695	COG1447	Phosphotransferase system cellobiose-specific component IIA
KCL43_RS09700	COG2390	Transcriptional regulator
KCL43_RS09705	COG1349	DNA-binding transcription factor activity
KCL43_RS09710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCL43_RS09785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCL43_RS09790	COG1428	Deoxynucleoside kinase
KCL43_RS09805	COG4120	Belongs to the binding-protein-dependent transport system permease family
KCL43_RS09830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCL43_RS09835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCL43_RS09845	COG1363	Peptidase, m42
KCL43_RS09850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCL43_RS09880	COG0602	queuosine metabolic process
KCL43_RS09900	COG1328	CTP reductase activity
KCL43_RS09925	COG1393	Belongs to the ArsC family
KCL43_RS09935	COG1058	Belongs to the CinA family
KCL43_RS09935	COG1546	Belongs to the CinA family
KCL43_RS09955	COG0519	Catalyzes the synthesis of GMP from XMP
KCL43_RS09960	COG0632	four-way junction helicase activity
KCL43_RS09965	COG2814	Major facilitator Superfamily
KCL43_RS09975	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCL43_RS09985	COG1438	arginine binding
KCL43_RS09990	COG0018	arginyl-trna synthetase
KCL43_RS09995	COG0488	(ABC) transporter
KCL43_RS10000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCL43_RS10005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCL43_RS10010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCL43_RS10015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KCL43_RS10025	COG1131	(ABC) transporter
KCL43_RS10045	COG0124	histidyl-tRNA synthetase
KCL43_RS10055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KCL43_RS10060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KCL43_RS10085	COG2197	response regulator
KCL43_RS10100	COG0577	efflux transmembrane transporter activity
KCL43_RS10100	COG1136	(ABC) transporter
KCL43_RS10120	COG0494	nUDIX hydrolase
KCL43_RS10140	COG1511	domain protein
KCL43_RS10195	COG0488	(ABC) transporter
KCL43_RS10200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCL43_RS10210	COG0516	GMP reductase activity
KCL43_RS10210	COG0517	IMP dehydrogenase activity
KCL43_RS10250	COG2501	S4 domain
KCL43_RS10260	COG0612	Peptidase, M16
KCL43_RS10270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCL43_RS10300	COG1760	l-serine dehydratase
KCL43_RS10305	COG1760	l-serine dehydratase
KCL43_RS10315	COG2816	NAD+ diphosphatase activity
KCL43_RS10335	COG0305	Participates in initiation and elongation during chromosome replication
KCL43_RS10360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCL43_RS10365	COG1475	DNA binding