locus-tag	class	description
SEZ_RS00010	COG0592	DNA-directed DNA polymerase activity
SEZ_RS00025	COG0012	GTP binding
SEZ_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SEZ_RS00040	COG2244	polysaccharide biosynthetic process
SEZ_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SEZ_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SEZ_RS00075	COG0531	amino acid
SEZ_RS00195	COG3942	CHAP domain
SEZ_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SEZ_RS00240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SEZ_RS00255	COG0151	Belongs to the GarS family
SEZ_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SEZ_RS00290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SEZ_RS00305	COG1012	belongs to the aldehyde dehydrogenase family
SEZ_RS00305	COG1454	alcohol dehydrogenase
SEZ_RS00315	COG1063	alcohol dehydrogenase
SEZ_RS00320	COG1064	alcohol dehydrogenase
SEZ_RS00325	COG1132	(ABC) transporter
SEZ_RS00330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SEZ_RS00340	COG1396	sequence-specific DNA binding
SEZ_RS00350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SEZ_RS00375	COG0089	rRNA binding
SEZ_RS00460	COG0201	protein transport
SEZ_RS00595	COG0582	viral genome integration into host DNA
SEZ_RS00605	COG2946	Replication initiation factor
SEZ_RS00615	COG1674	ftsk spoiiie
SEZ_RS00655	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SEZ_RS00670	COG1121	(ABC) transporter
SEZ_RS00675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SEZ_RS00685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SEZ_RS00685	COG4499	WXG100 protein secretion system (Wss), protein YukC
SEZ_RS00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SEZ_RS00720	COG1136	(ABC) transporter
SEZ_RS00725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SEZ_RS00730	COG1459	type II secretion system
SEZ_RS00735	COG4537	Required for transformation and DNA binding
SEZ_RS00760	COG2801	Transposase and inactivated derivatives
SEZ_RS00785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEZ_RS00800	COG3959	Transketolase, thiamine diphosphate binding domain
SEZ_RS00805	COG3958	Transketolase
SEZ_RS00810	COG3590	peptidase
SEZ_RS00835	COG0450	alkyl hydroperoxide reductase
SEZ_RS00850	COG4463	regulation of RNA biosynthetic process
SEZ_RS00855	COG0542	response to heat
SEZ_RS00895	COG1051	belongs to the nudix hydrolase family
SEZ_RS00915	COG1116	anion transmembrane transporter activity
SEZ_RS00935	COG0564	pseudouridine synthase activity
SEZ_RS00955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SEZ_RS00995	COG3037	sugar-specific permease SgaT UlaA
SEZ_RS01015	COG3623	hexulose-6-phosphate isomerase
SEZ_RS01035	COG4175	Glycine betaine
SEZ_RS01035	COG3448	diguanylate cyclase activity
SEZ_RS01055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SEZ_RS01055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SEZ_RS01060	COG1832	CoA-binding protein
SEZ_RS01100	COG1268	BioY protein
SEZ_RS01105	COG1234	tRNA 3'-trailer cleavage
SEZ_RS01130	COG1215	transferase activity, transferring glycosyl groups
SEZ_RS01160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEZ_RS01160	COG3711	transcriptional antiterminator
SEZ_RS01170	COG3730	PTS system glucitol sorbitol-specific
SEZ_RS01175	COG3732	PTS system glucitol sorbitol-specific
SEZ_RS01210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SEZ_RS01215	COG0705	Rhomboid family
SEZ_RS01215	COG0457	Tetratricopeptide repeat
SEZ_RS01235	COG1132	(ABC) transporter
SEZ_RS01240	COG1132	(ABC) transporter
SEZ_RS01250	COG0756	dUTP diphosphatase activity
SEZ_RS01300	COG1131	(ABC) transporter
SEZ_RS01335	COG1847	R3H domain protein
SEZ_RS01355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEZ_RS01355	COG2190	(PTS) system
SEZ_RS01355	COG1263	PTS System
SEZ_RS01360	COG2190	(PTS) system
SEZ_RS01360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEZ_RS01360	COG1263	PTS System
SEZ_RS01380	COG1175	transmembrane transport
SEZ_RS01385	COG0395	ABC-type sugar transport system, permease component
SEZ_RS01390	COG2731	YhcH YjgK YiaL family protein
SEZ_RS01400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SEZ_RS01410	COG3458	cephalosporin-C deacetylase activity
SEZ_RS01415	COG1737	Transcriptional regulator
SEZ_RS01420	COG0084	hydrolase, TatD family'
SEZ_RS01450	COG1564	THIamine pyrophosphokinase
SEZ_RS01465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SEZ_RS01500	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SEZ_RS01520	COG0174	glutamine synthetase
SEZ_RS01525	COG4166	transmembrane transport
SEZ_RS01530	COG0601	transmembrane transport
SEZ_RS01535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SEZ_RS01540	COG0444	Belongs to the ABC transporter superfamily
SEZ_RS01545	COG4608	Belongs to the ABC transporter superfamily
SEZ_RS01560	COG1214	PFAM Peptidase M22, glycoprotease
SEZ_RS01575	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SEZ_RS01585	COG2081	HI0933 family
SEZ_RS01600	COG0789	Transcriptional regulator
SEZ_RS01610	COG2801	Transposase and inactivated derivatives
SEZ_RS01620	COG0582	viral genome integration into host DNA
SEZ_RS01690	COG5002	protein histidine kinase activity
SEZ_RS01730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SEZ_RS01735	COG2814	Major facilitator Superfamily
SEZ_RS01745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SEZ_RS01755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SEZ_RS01760	COG1882	Formate acetyltransferase
SEZ_RS01775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SEZ_RS01780	COG0681	Belongs to the peptidase S26 family
SEZ_RS01795	COG1286	toxin biosynthetic process
SEZ_RS01810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SEZ_RS01815	COG3118	belongs to the thioredoxin family
SEZ_RS01830	COG1194	a g-specific adenine glycosylase
SEZ_RS01865	COG2801	Transposase and inactivated derivatives
SEZ_RS01885	COG0006	proline dipeptidase activity
SEZ_RS01890	COG2131	deaminase
SEZ_RS01905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SEZ_RS01940	COG1609	Transcriptional regulator
SEZ_RS01945	COG1621	beta-fructofuranosidase activity
SEZ_RS01950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEZ_RS01950	COG2190	(PTS) system
SEZ_RS01950	COG1263	PTS System
SEZ_RS01960	COG1940	carbohydrate kinase activity
SEZ_RS01965	COG1482	cell wall glycoprotein biosynthetic process
SEZ_RS01985	COG3942	CHAP domain
SEZ_RS01985	COG1388	LysM domain
SEZ_RS02010	COG1120	ATPase activity
SEZ_RS02015	COG4988	ABC transporter
SEZ_RS02020	COG1132	(ABC) transporter
SEZ_RS02035	COG1129	ABC transporter
SEZ_RS02040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SEZ_RS02045	COG0252	asparaginase activity
SEZ_RS02050	COG0561	phosphatase activity
SEZ_RS02070	COG1335	isochorismatase
SEZ_RS02090	COG0697	spore germination
SEZ_RS02095	COG2261	transglycosylase associated protein
SEZ_RS02105	COG3830	Belongs to the UPF0237 family
SEZ_RS02115	COG0588	phosphoglycerate mutase activity
SEZ_RS02120	COG1876	peptidase activity
SEZ_RS02150	COG1024	Enoyl-CoA hydratase
SEZ_RS02170	COG2070	2-Nitropropane dioxygenase
SEZ_RS02175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SEZ_RS02180	COG1028	Short-chain dehydrogenase reductase Sdr
SEZ_RS02185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SEZ_RS02230	COG3716	PTS system mannose fructose sorbose family IID component
SEZ_RS02235	COG3715	PTS system
SEZ_RS02250	COG0561	phosphatase activity
SEZ_RS02255	COG2252	PERMEase
SEZ_RS02260	COG0802	atpase or kinase
SEZ_RS02270	COG1316	TRANSCRIPTIONal
SEZ_RS02280	COG0537	adenosine 5'-monophosphoramidase activity
SEZ_RS02295	COG4473	ABC transporter
SEZ_RS02325	COG0195	Participates in both transcription termination and antitermination
SEZ_RS02330	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SEZ_RS02360	COG2217	Heavy metal translocating P-type atpase
SEZ_RS02400	COG3711	transcriptional antiterminator
SEZ_RS02405	COG1447	Phosphotransferase system cellobiose-specific component IIA
SEZ_RS02410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEZ_RS02410	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEZ_RS02425	COG2860	membrane
SEZ_RS02430	COG0561	phosphatase activity
SEZ_RS02445	COG1609	Transcriptional regulator
SEZ_RS02450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SEZ_RS02455	COG1869	D-ribose catabolic process
SEZ_RS02465	COG1172	Belongs to the binding-protein-dependent transport system permease family
SEZ_RS02470	COG1879	ABC-type sugar transport system periplasmic component
SEZ_RS02480	COG1283	sodium-dependent phosphate transmembrane transporter activity
SEZ_RS02490	COG0656	L-ascorbic acid biosynthetic process
SEZ_RS02515	COG1755	Isoprenylcysteine carboxyl methyltransferase
SEZ_RS02560	COG1131	(ABC) transporter
SEZ_RS02600	COG5433	transposase activity
SEZ_RS02605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SEZ_RS02610	COG1393	Belongs to the ArsC family
SEZ_RS02615	COG0708	Exodeoxyribonuclease III
SEZ_RS02670	COG2274	protein secretion by the type I secretion system
SEZ_RS02675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SEZ_RS02700	COG1114	Component of the transport system for branched-chain amino acids
SEZ_RS02825	COG1518	maintenance of DNA repeat elements
SEZ_RS02830	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SEZ_RS02845	COG0785	Cytochrome C biogenesis protein
SEZ_RS02850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SEZ_RS02860	COG2207	Transcriptional regulator
SEZ_RS02860	COG4753	response regulator
SEZ_RS02865	COG2972	Histidine kinase
SEZ_RS02870	COG2315	Protein conserved in bacteria
SEZ_RS02900	COG0454	-acetyltransferase
SEZ_RS02910	COG1288	antiporter activity
SEZ_RS02915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SEZ_RS02920	COG0549	Belongs to the carbamate kinase family
SEZ_RS02930	COG0742	ribosomal rna small subunit methyltransferase
SEZ_RS02940	COG3480	Lon protease (S16) C-terminal proteolytic domain
SEZ_RS02945	COG4470	Protein conserved in bacteria
SEZ_RS02955	COG1131	(ABC) transporter
SEZ_RS02960	COG0842	Transport permease protein
SEZ_RS02965	COG4585	Histidine kinase
SEZ_RS02970	COG2197	response regulator
SEZ_RS02980	COG0783	Belongs to the Dps family
SEZ_RS02985	COG4483	Protein conserved in bacteria
SEZ_RS02990	COG1940	carbohydrate kinase activity
SEZ_RS02995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SEZ_RS03000	COG1217	gtp-binding protein TYPA
SEZ_RS03025	COG0849	cell division
SEZ_RS03035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SEZ_RS03055	COG3599	regulation of cell shape
SEZ_RS03070	COG0494	nUDIX hydrolase
SEZ_RS03075	COG0542	response to heat
SEZ_RS03080	COG4703	Protein of unknown function (DUF1797)
SEZ_RS03095	COG1126	abc transporter atp-binding protein
SEZ_RS03100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SEZ_RS03110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SEZ_RS03130	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SEZ_RS03135	COG1438	arginine binding
SEZ_RS03140	COG0497	DNA recombination
SEZ_RS03155	COG2755	lipolytic protein G-D-S-L family
SEZ_RS03160	COG4698	Protein conserved in bacteria
SEZ_RS03180	COG1396	sequence-specific DNA binding
SEZ_RS03190	COG0167	dihydroorotate dehydrogenase activity
SEZ_RS03205	COG1827	regulation of RNA biosynthetic process
SEZ_RS03215	COG2116	formate transmembrane transporter activity
SEZ_RS03220	COG0768	penicillin binding
SEZ_RS03235	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SEZ_RS03250	COG0513	Belongs to the DEAD box helicase family
SEZ_RS03265	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SEZ_RS03270	COG0204	Acyl-transferase
SEZ_RS03280	COG0658	competence protein
SEZ_RS03280	COG2333	competence protein COMEC
SEZ_RS03310	COG1187	pseudouridine synthase activity
SEZ_RS03335	COG0546	phosphoglycolate phosphatase activity
SEZ_RS03340	COG4122	O-methyltransferase activity
SEZ_RS03360	COG0726	polysaccharide deacetylase
SEZ_RS03365	COG0513	Belongs to the DEAD box helicase family
SEZ_RS03385	COG1956	GAF domain-containing protein
SEZ_RS03390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SEZ_RS03425	COG2211	Major facilitator Superfamily
SEZ_RS03435	COG3250	beta-galactosidase activity
SEZ_RS03440	COG2186	Transcriptional regulator
SEZ_RS03445	COG0800	Aldolase
SEZ_RS03460	COG1028	Short-chain dehydrogenase reductase Sdr
SEZ_RS03480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SEZ_RS03485	COG4109	DRTGG domain
SEZ_RS03490	COG0024	Methionine aminopeptidase
SEZ_RS03510	COG1316	TRANSCRIPTIONal
SEZ_RS03520	COG0588	phosphoglycerate mutase activity
SEZ_RS03530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SEZ_RS03535	COG3859	Proton-coupled thiamine transporter YuaJ
SEZ_RS03555	COG0386	Belongs to the glutathione peroxidase family
SEZ_RS03560	COG1164	Oligoendopeptidase f
SEZ_RS03570	COG0772	Belongs to the SEDS family
SEZ_RS03575	COG1396	sequence-specific DNA binding
SEZ_RS03585	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SEZ_RS03595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SEZ_RS03600	COG2884	Cell division ATP-binding protein ftsE
SEZ_RS03605	COG2177	Part of the ABC transporter FtsEX involved in
SEZ_RS03615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SEZ_RS03615	COG1199	ATP-dependent helicase activity
SEZ_RS03625	COG0436	Aminotransferase
SEZ_RS03630	COG0017	Asparaginyl-tRNA synthetase
SEZ_RS03670	COG2188	Transcriptional regulator
SEZ_RS03675	COG2222	sugar isomerase
SEZ_RS03680	COG3684	Belongs to the aldolase LacD family
SEZ_RS03685	COG2188	Transcriptional regulator
SEZ_RS03695	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEZ_RS03695	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEZ_RS03700	COG3715	PTS system
SEZ_RS03705	COG3716	PTS system mannose fructose sorbose family IID component
SEZ_RS03720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SEZ_RS03725	COG2153	protein acetylation
SEZ_RS03735	COG0716	FMN binding
SEZ_RS03765	COG1476	TRANSCRIPTIONal
SEZ_RS03790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SEZ_RS03795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEZ_RS03805	COG1012	belongs to the aldehyde dehydrogenase family
SEZ_RS03810	COG0772	Belongs to the SEDS family
SEZ_RS03865	COG2801	Transposase and inactivated derivatives
SEZ_RS03880	COG4708	membrane
SEZ_RS03890	COG1597	lipid kinase activity
SEZ_RS03895	COG1523	belongs to the glycosyl hydrolase 13 family
SEZ_RS03900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SEZ_RS03905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SEZ_RS03910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SEZ_RS03920	COG0058	SHG alpha-glucan phosphorylase activity
SEZ_RS04005	COG0577	efflux transmembrane transporter activity
SEZ_RS04020	COG1309	transcriptional regulator
SEZ_RS04070	COG1523	belongs to the glycosyl hydrolase 13 family
SEZ_RS04075	COG1595	DNA-templated transcription, initiation
SEZ_RS04120	COG0436	Aminotransferase
SEZ_RS04125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SEZ_RS04135	COG1970	mechanosensitive ion channel activity
SEZ_RS04140	COG0358	DNA primase activity
SEZ_RS04145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SEZ_RS04150	COG2151	metal-sulfur cluster biosynthetic enzyme
SEZ_RS04155	COG1091	dTDP-4-dehydrorhamnose reductase activity
SEZ_RS04165	COG0463	Glycosyl transferase, family 2
SEZ_RS04190	COG0463	Glycosyl transferase, family 2
SEZ_RS04210	COG0297	glycogen (starch) synthase activity
SEZ_RS04215	COG1368	sulfuric ester hydrolase activity
SEZ_RS04220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SEZ_RS04270	COG1368	sulfuric ester hydrolase activity
SEZ_RS04275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SEZ_RS04295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SEZ_RS04305	COG1104	cysteine desulfurase activity
SEZ_RS04310	COG0301	tRNA thio-modification
SEZ_RS04330	COG5433	transposase activity
SEZ_RS04345	COG1131	(ABC) transporter
SEZ_RS04350	COG1725	Transcriptional regulator
SEZ_RS04365	COG0469	pyruvate kinase activity
SEZ_RS04380	COG2824	Alkylphosphonate utilization operon protein PhnA
SEZ_RS04385	COG0765	amino acid transport
SEZ_RS04390	COG1126	abc transporter atp-binding protein
SEZ_RS04395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SEZ_RS04400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SEZ_RS04405	COG1115	amino acid carrier protein
SEZ_RS04450	COG1136	(ABC) transporter
SEZ_RS04450	COG4591	ABC-type transport system involved in lipoprotein release permease component
SEZ_RS04480	COG0196	riboflavin kinase activity
SEZ_RS04495	COG0483	inositol monophosphate 1-phosphatase activity
SEZ_RS04500	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SEZ_RS04500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SEZ_RS04510	COG0573	inorganic phosphate transmembrane transporter activity
SEZ_RS04515	COG0581	inorganic phosphate transmembrane transporter activity
SEZ_RS04530	COG0704	Plays a role in the regulation of phosphate uptake
SEZ_RS04540	COG0745	RESPONSE REGULATOR receiver
SEZ_RS04545	COG5002	protein histidine kinase activity
SEZ_RS04605	COG2813	Specifically methylates the guanine in position
SEZ_RS04610	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SEZ_RS04625	COG1744	ABC transporter substrate-binding protein PnrA-like
SEZ_RS04630	COG3845	ABC transporter
SEZ_RS04635	COG4603	Belongs to the binding-protein-dependent transport system permease family
SEZ_RS04640	COG1079	Belongs to the binding-protein-dependent transport system permease family
SEZ_RS04645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SEZ_RS04650	COG4684	Psort location CytoplasmicMembrane, score
SEZ_RS04655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SEZ_RS04675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SEZ_RS04680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SEZ_RS04685	COG1328	CTP reductase activity
SEZ_RS04685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SEZ_RS04690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SEZ_RS04705	COG0488	(ABC) transporter
SEZ_RS04720	COG5433	transposase activity
SEZ_RS04725	COG1597	lipid kinase activity
SEZ_RS04730	COG1272	protein, Hemolysin III
SEZ_RS04740	COG2226	methyltransferase
SEZ_RS04765	COG1131	(ABC) transporter
SEZ_RS04795	COG1136	(ABC) transporter
SEZ_RS04795	COG0577	efflux transmembrane transporter activity
SEZ_RS04800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SEZ_RS04810	COG0758	DNA mediated transformation
SEZ_RS04815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SEZ_RS04840	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SEZ_RS04860	COG2851	Citrate transporter
SEZ_RS04875	COG0511	ligase activity, forming carbon-carbon bonds
SEZ_RS04880	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SEZ_RS04920	COG1136	(ABC) transporter
SEZ_RS04925	COG0577	efflux transmembrane transporter activity
SEZ_RS04930	COG0745	RESPONSE REGULATOR receiver
SEZ_RS04935	COG5002	protein histidine kinase activity
SEZ_RS04950	COG1396	sequence-specific DNA binding
SEZ_RS04965	COG2188	Transcriptional regulator
SEZ_RS04975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SEZ_RS04995	COG0803	Belongs to the bacterial solute-binding protein 9 family
SEZ_RS05000	COG0346	lactoylglutathione lyase activity
SEZ_RS05005	COG3764	Sortase (surface protein transpeptidase)
SEZ_RS05040	COG1247	-acetyltransferase
SEZ_RS05045	COG0009	L-threonylcarbamoyladenylate synthase
SEZ_RS05050	COG2890	protein-(glutamine-N5) methyltransferase activity
SEZ_RS05070	COG1942	4-Oxalocrotonate Tautomerase
SEZ_RS05080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SEZ_RS05085	COG0516	GMP reductase activity
SEZ_RS05090	COG1174	glycine betaine transport
SEZ_RS05105	COG4221	oxidoreductase activity
SEZ_RS05115	COG0564	pseudouridine synthase activity
SEZ_RS05125	COG2357	RelA SpoT domain protein
SEZ_RS05140	COG1104	cysteine desulfurase activity
SEZ_RS05155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SEZ_RS05165	COG0628	permease
SEZ_RS05190	COG1177	transmembrane transport
SEZ_RS05195	COG1176	ABC-type spermidine putrescine transport system, permease component I
SEZ_RS05205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SEZ_RS05210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SEZ_RS05225	COG0302	gtp cyclohydrolase
SEZ_RS05235	COG0083	homoserine kinase activity
SEZ_RS05240	COG0460	homoserine dehydrogenase
SEZ_RS05255	COG0105	UTP biosynthetic process
SEZ_RS05270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SEZ_RS05285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SEZ_RS05295	COG3425	synthase
SEZ_RS05325	COG1132	(ABC) transporter
SEZ_RS05335	COG0737	Belongs to the 5'-nucleotidase family
SEZ_RS05340	COG0242	peptide deformylase activity
SEZ_RS05345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SEZ_RS05350	COG1132	(ABC) transporter
SEZ_RS05360	COG0488	(ABC) transporter
SEZ_RS05380	COG1705	Flagellar rod assembly protein muramidase FlgJ
SEZ_RS05380	COG1388	LysM domain
SEZ_RS05400	COG1476	TRANSCRIPTIONal
SEZ_RS05405	COG1705	Flagellar rod assembly protein muramidase FlgJ
SEZ_RS05405	COG1388	LysM domain
SEZ_RS05410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEZ_RS05410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SEZ_RS05410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SEZ_RS05415	COG1105	Belongs to the carbohydrate kinase PfkB family
SEZ_RS05420	COG1349	DNA-binding transcription factor activity
SEZ_RS05450	COG2801	Transposase and inactivated derivatives
SEZ_RS05475	COG1837	Belongs to the UPF0109 family
SEZ_RS05490	COG0577	efflux transmembrane transporter activity
SEZ_RS05495	COG1136	(ABC) transporter
SEZ_RS05500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SEZ_RS05505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SEZ_RS05535	COG0564	pseudouridine synthase activity
SEZ_RS05550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SEZ_RS05600	COG0539	negative regulation of cytoplasmic translation
SEZ_RS05620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SEZ_RS05635	COG0187	DNA topoisomerase II activity
SEZ_RS05660	COG0765	amino acid transport
SEZ_RS05680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SEZ_RS05695	COG0583	DNA-binding transcription factor activity
SEZ_RS05785	COG2207	Transcriptional regulator
SEZ_RS05785	COG4753	response regulator
SEZ_RS05795	COG3716	PTS system mannose fructose sorbose family IID component
SEZ_RS05800	COG3715	PTS system
SEZ_RS05820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SEZ_RS05850	COG2274	protein secretion by the type I secretion system
SEZ_RS05855	COG2274	protein secretion by the type I secretion system
SEZ_RS05895	COG0647	UMP catabolic process
SEZ_RS05905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SEZ_RS05925	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SEZ_RS05935	COG3442	glutamine amidotransferase
SEZ_RS05945	COG0095	Lipoate-protein ligase
SEZ_RS05955	COG0508	dehydrogenase complex catalyzes the overall conversion of
SEZ_RS05960	COG0508	dehydrogenase complex catalyzes the overall conversion of
SEZ_RS05960	COG0022	dehydrogenase e1 component
SEZ_RS05965	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SEZ_RS05970	COG0488	(ABC) transporter
SEZ_RS06005	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SEZ_RS06010	COG0457	Tetratricopeptide repeat
SEZ_RS06015	COG0628	permease
SEZ_RS06020	COG1051	belongs to the nudix hydrolase family
SEZ_RS06025	COG1088	dTDP-glucose 4,6-dehydratase activity
SEZ_RS06035	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SEZ_RS06040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SEZ_RS06050	COG2384	SAM-dependent methyltransferase
SEZ_RS06055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SEZ_RS06075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SEZ_RS06075	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SEZ_RS06080	COG0300	oxidoreductase activity
SEZ_RS06090	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SEZ_RS06095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SEZ_RS06110	COG0058	SHG alpha-glucan phosphorylase activity
SEZ_RS06115	COG1640	4-alpha-glucanotransferase
SEZ_RS06120	COG1609	Transcriptional regulator
SEZ_RS06130	COG1175	transmembrane transport
SEZ_RS06135	COG3833	ABC-type maltose transport systems, permease component
SEZ_RS06150	COG1175	transmembrane transport
SEZ_RS06160	COG0366	Alpha amylase catalytic
SEZ_RS06165	COG2182	Extracellular solute-binding protein
SEZ_RS06170	COG0657	acetylesterase activity
SEZ_RS06175	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SEZ_RS06185	COG1696	Membrane protein involved in D-alanine export
SEZ_RS06205	COG0765	amino acid transport
SEZ_RS06210	COG1126	abc transporter atp-binding protein
SEZ_RS06215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEZ_RS06225	COG1447	Phosphotransferase system cellobiose-specific component IIA
SEZ_RS06235	COG3711	transcriptional antiterminator
SEZ_RS06235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SEZ_RS06265	COG2309	aminopeptidase activity
SEZ_RS06270	COG1187	pseudouridine synthase activity
SEZ_RS06280	COG2814	Major facilitator Superfamily
SEZ_RS06310	COG5492	domain, Protein
SEZ_RS06315	COG0800	Aldolase
SEZ_RS06330	COG1028	Short-chain dehydrogenase reductase Sdr
SEZ_RS06345	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEZ_RS06350	COG3715	PTS system
SEZ_RS06355	COG3716	PTS system mannose fructose sorbose family IID component
SEZ_RS06360	COG1609	Transcriptional regulator
SEZ_RS06395	COG1078	dGTPase activity
SEZ_RS06440	COG1191	sigma factor activity
SEZ_RS06455	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SEZ_RS06460	COG1518	maintenance of DNA repeat elements
SEZ_RS06525	COG2801	Transposase and inactivated derivatives
SEZ_RS06540	COG2814	Major facilitator Superfamily
SEZ_RS06555	COG4443	Transcriptional Coactivator p15 (PC4)
SEZ_RS06565	COG0826	peptidase U32
SEZ_RS06610	COG2183	response to ionizing radiation
SEZ_RS06625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SEZ_RS06635	COG0573	inorganic phosphate transmembrane transporter activity
SEZ_RS06640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SEZ_RS06645	COG5002	protein histidine kinase activity
SEZ_RS06650	COG0745	RESPONSE REGULATOR receiver
SEZ_RS06660	COG0701	Predicted permease
SEZ_RS06680	COG3711	transcriptional antiterminator
SEZ_RS06685	COG0552	protein localization to endoplasmic reticulum
SEZ_RS06690	COG0561	phosphatase activity
SEZ_RS06695	COG0561	phosphatase activity
SEZ_RS06705	COG1136	(ABC) transporter
SEZ_RS06740	COG1196	nuclear chromosome segregation
SEZ_RS06745	COG0571	ribonuclease III activity
SEZ_RS06760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SEZ_RS06765	COG5002	protein histidine kinase activity
SEZ_RS06770	COG0745	RESPONSE REGULATOR receiver
SEZ_RS06785	COG0183	Belongs to the thiolase family
SEZ_RS06805	COG4555	ABC transporter
SEZ_RS06810	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SEZ_RS06815	COG0438	transferase activity, transferring glycosyl groups
SEZ_RS06830	COG1609	Transcriptional regulator
SEZ_RS06845	COG0463	Glycosyl transferase, family 2
SEZ_RS06855	COG0557	exoribonuclease II activity
SEZ_RS06890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEZ_RS06895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEZ_RS06900	COG1447	Phosphotransferase system cellobiose-specific component IIA
SEZ_RS06905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEZ_RS06915	COG1940	carbohydrate kinase activity
SEZ_RS06925	COG2610	gluconate transmembrane transporter activity
SEZ_RS06930	COG1028	Short-chain dehydrogenase reductase Sdr
SEZ_RS06940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SEZ_RS06945	COG0183	Belongs to the thiolase family
SEZ_RS06950	COG0583	DNA-binding transcription factor activity
SEZ_RS06965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SEZ_RS06980	COG1573	uracil-dna glycosylase
SEZ_RS06985	COG1702	phosphate starvation-inducible protein PhoH
SEZ_RS07020	COG0444	Belongs to the ABC transporter superfamily
SEZ_RS07025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SEZ_RS07030	COG0601	transmembrane transport
SEZ_RS07035	COG0747	negative chemotaxis
SEZ_RS07105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SEZ_RS07125	COG0673	inositol 2-dehydrogenase activity
SEZ_RS07135	COG1028	Short-chain dehydrogenase reductase Sdr
SEZ_RS07150	COG1376	ErfK ybiS ycfS ynhG family protein
SEZ_RS07165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SEZ_RS07185	COG1605	Chorismate mutase
SEZ_RS07185	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SEZ_RS07190	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SEZ_RS07215	COG3250	beta-galactosidase activity
SEZ_RS07220	COG4753	response regulator
SEZ_RS07220	COG2207	Transcriptional regulator
SEZ_RS07225	COG2972	Histidine kinase
SEZ_RS07235	COG1653	transport
SEZ_RS07240	COG0395	ABC-type sugar transport system, permease component
SEZ_RS07245	COG1175	transmembrane transport
SEZ_RS07250	COG1940	carbohydrate kinase activity
SEZ_RS07260	COG2723	6-phospho-beta-galactosidase activity
SEZ_RS07265	COG3291	Pkd domain containing protein
SEZ_RS07265	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SEZ_RS07280	COG0383	alpha-mannosidase activity
SEZ_RS07285	COG1136	(ABC) transporter
SEZ_RS07335	COG2801	Transposase and inactivated derivatives
SEZ_RS07350	COG2274	protein secretion by the type I secretion system
SEZ_RS07365	COG3290	protein histidine kinase activity
SEZ_RS07405	COG2801	Transposase and inactivated derivatives
SEZ_RS07410	COG3655	Transcriptional regulator
SEZ_RS07435	COG1204	response to ionizing radiation
SEZ_RS07520	COG1040	competence protein
SEZ_RS07525	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SEZ_RS07530	COG1739	Uncharacterized protein family UPF0029
SEZ_RS07540	COG1098	S1 RNA binding domain
SEZ_RS07550	COG2197	response regulator
SEZ_RS07555	COG4585	Histidine kinase
SEZ_RS07565	COG2815	serine threonine protein kinase
SEZ_RS07565	COG0515	serine threonine protein kinase
SEZ_RS07575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SEZ_RS07575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SEZ_RS07580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SEZ_RS07585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SEZ_RS07605	COG1854	S-ribosylhomocysteine lyase activity
SEZ_RS07615	COG0116	Belongs to the methyltransferase superfamily
SEZ_RS07635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SEZ_RS07640	COG3579	cysteine-type endopeptidase activity
SEZ_RS07650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SEZ_RS07655	COG1113	amino acid transport
SEZ_RS07660	COG0492	ferredoxin-NADP+ reductase activity
SEZ_RS07670	COG1126	abc transporter atp-binding protein
SEZ_RS07690	COG0513	Belongs to the DEAD box helicase family
SEZ_RS07700	COG0768	penicillin binding
SEZ_RS07805	COG1774	PSP1 C-terminal conserved region
SEZ_RS07810	COG0470	DNA polymerase III
SEZ_RS07840	COG2244	polysaccharide biosynthetic process
SEZ_RS07850	COG1120	ATPase activity
SEZ_RS07855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SEZ_RS07860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SEZ_RS07865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SEZ_RS07885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SEZ_RS07890	COG1253	flavin adenine dinucleotide binding
SEZ_RS07895	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SEZ_RS07905	COG1242	4 iron, 4 sulfur cluster binding
SEZ_RS07910	COG0671	phosphoesterase, PA-phosphatase related
SEZ_RS07915	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SEZ_RS07975	COG1187	pseudouridine synthase activity
SEZ_RS08035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SEZ_RS08045	COG1254	Belongs to the acylphosphatase family
SEZ_RS08060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SEZ_RS08090	COG1484	DNA-dependent DNA replication
SEZ_RS08105	COG5002	protein histidine kinase activity
SEZ_RS08110	COG0745	RESPONSE REGULATOR receiver
SEZ_RS08125	COG1704	LemA family
SEZ_RS08135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SEZ_RS08140	COG0569	domain protein
SEZ_RS08165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SEZ_RS08170	COG1464	Belongs to the NlpA lipoprotein family
SEZ_RS08175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SEZ_RS08185	COG0789	Transcriptional regulator
SEZ_RS08195	COG2226	methyltransferase
SEZ_RS08200	COG0799	negative regulation of ribosome biogenesis
SEZ_RS08205	COG1713	HD superfamily hydrolase involved in NAD metabolism
SEZ_RS08210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SEZ_RS08215	COG1534	Rna-binding protein
SEZ_RS08220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SEZ_RS08225	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SEZ_RS08270	COG0444	Belongs to the ABC transporter superfamily
SEZ_RS08275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SEZ_RS08280	COG0601	transmembrane transport
SEZ_RS08285	COG4166	transmembrane transport
SEZ_RS08290	COG1686	Belongs to the peptidase S11 family
SEZ_RS08295	COG1686	Belongs to the peptidase S11 family
SEZ_RS08305	COG0719	Fe-S assembly protein
SEZ_RS08315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SEZ_RS08320	COG0719	Fe-S assembly protein
SEZ_RS08330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SEZ_RS08345	COG0765	amino acid transport
SEZ_RS08350	COG1126	abc transporter atp-binding protein
SEZ_RS08375	COG0191	fructose-bisphosphate aldolase activity
SEZ_RS08405	COG0366	Alpha amylase catalytic
SEZ_RS08410	COG0668	transmembrane transport
SEZ_RS08420	COG4720	Psort location CytoplasmicMembrane, score
SEZ_RS08425	COG0351	phosphomethylpyrimidine kinase
SEZ_RS08425	COG0352	thiamine-phosphate diphosphorylase activity
SEZ_RS08435	COG0527	aspartate kinase activity
SEZ_RS08480	COG0803	Belongs to the bacterial solute-binding protein 9 family
SEZ_RS08490	COG5433	transposase activity
SEZ_RS08495	COG1597	lipid kinase activity
SEZ_RS08500	COG1609	Transcriptional regulator
SEZ_RS08505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SEZ_RS08510	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SEZ_RS08515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SEZ_RS08520	COG2017	converts alpha-aldose to the beta-anomer
SEZ_RS08530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SEZ_RS08550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SEZ_RS08560	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SEZ_RS08570	COG1045	serine acetyltransferase
SEZ_RS08600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SEZ_RS08605	COG1846	Transcriptional regulator
SEZ_RS08620	COG0442	prolyl-tRNA aminoacylation
SEZ_RS08630	COG4589	Belongs to the CDS family
SEZ_RS08640	COG1862	Preprotein translocase
SEZ_RS08655	COG3842	ATPase activity
SEZ_RS08700	COG2190	(PTS) system
SEZ_RS08700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SEZ_RS08700	COG1263	PTS System
SEZ_RS08710	COG1609	Transcriptional regulator
SEZ_RS08725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SEZ_RS08760	COG0512	Glutamine amidotransferase of anthranilate synthase
SEZ_RS08765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SEZ_RS08830	COG1882	Formate acetyltransferase
SEZ_RS08835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEZ_RS08840	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SEZ_RS08845	COG1447	Phosphotransferase system cellobiose-specific component IIA
SEZ_RS08850	COG2390	Transcriptional regulator
SEZ_RS08855	COG1349	DNA-binding transcription factor activity
SEZ_RS08860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SEZ_RS08935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SEZ_RS08940	COG1428	Deoxynucleoside kinase
SEZ_RS08955	COG4120	Belongs to the binding-protein-dependent transport system permease family
SEZ_RS08990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SEZ_RS08995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SEZ_RS09005	COG1363	Peptidase, m42
SEZ_RS09010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SEZ_RS09040	COG0602	queuosine metabolic process
SEZ_RS09055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SEZ_RS09055	COG1328	CTP reductase activity
SEZ_RS09070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SEZ_RS09080	COG1393	Belongs to the ArsC family
SEZ_RS09100	COG2801	Transposase and inactivated derivatives
SEZ_RS09135	COG0519	Catalyzes the synthesis of GMP from XMP
SEZ_RS09145	COG2814	Major facilitator Superfamily
SEZ_RS09165	COG1438	arginine binding
SEZ_RS09175	COG0488	(ABC) transporter
SEZ_RS09180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SEZ_RS09185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SEZ_RS09190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SEZ_RS09230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SEZ_RS09245	COG2197	response regulator
SEZ_RS09260	COG0577	efflux transmembrane transporter activity
SEZ_RS09260	COG1136	(ABC) transporter
SEZ_RS09280	COG0494	nUDIX hydrolase
SEZ_RS09300	COG1511	domain protein
SEZ_RS09345	COG0305	Participates in initiation and elongation during chromosome replication
SEZ_RS09365	COG2816	NAD+ diphosphatase activity
SEZ_RS09375	COG1760	l-serine dehydratase
SEZ_RS09380	COG1760	l-serine dehydratase
SEZ_RS09410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SEZ_RS09420	COG0612	Peptidase, M16
SEZ_RS09430	COG2501	S4 domain
SEZ_RS09465	COG0516	GMP reductase activity
SEZ_RS09465	COG0517	IMP dehydrogenase activity
SEZ_RS09480	COG0488	(ABC) transporter
SEZ_RS09510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SEZ_RS09515	COG1475	DNA binding
SEZ_RS09550	COG1396	sequence-specific DNA binding