locus-tag	class	description
KV238_RS00010	COG0826	peptidase U32
KV238_RS00055	COG2183	response to ionizing radiation
KV238_RS00065	COG0704	Plays a role in the regulation of phosphate uptake
KV238_RS00070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KV238_RS00080	COG0573	inorganic phosphate transmembrane transporter activity
KV238_RS00085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KV238_RS00090	COG5002	protein histidine kinase activity
KV238_RS00095	COG0745	RESPONSE REGULATOR receiver
KV238_RS00105	COG0701	Predicted permease
KV238_RS00110	COG3689	TIGRFAM TIGR03943 family protein
KV238_RS00120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV238_RS00120	COG1263	PTS System
KV238_RS00120	COG2190	(PTS) system
KV238_RS00125	COG3711	transcriptional antiterminator
KV238_RS00130	COG0552	protein localization to endoplasmic reticulum
KV238_RS00135	COG0561	phosphatase activity
KV238_RS00140	COG0561	phosphatase activity
KV238_RS00180	COG1196	nuclear chromosome segregation
KV238_RS00185	COG0571	ribonuclease III activity
KV238_RS00205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KV238_RS00210	COG5002	protein histidine kinase activity
KV238_RS00215	COG0745	RESPONSE REGULATOR receiver
KV238_RS00230	COG0183	Belongs to the thiolase family
KV238_RS00250	COG4555	ABC transporter
KV238_RS00265	COG1131	(ABC) transporter
KV238_RS00295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KV238_RS00300	COG0438	transferase activity, transferring glycosyl groups
KV238_RS00315	COG1609	Transcriptional regulator
KV238_RS00320	COG0006	proline dipeptidase activity
KV238_RS00335	COG0463	Glycosyl transferase, family 2
KV238_RS00345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KV238_RS00350	COG0557	exoribonuclease II activity
KV238_RS00360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KV238_RS00395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV238_RS00400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV238_RS00405	COG1447	Phosphotransferase system cellobiose-specific component IIA
KV238_RS00410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV238_RS00420	COG1940	carbohydrate kinase activity
KV238_RS00430	COG2610	gluconate transmembrane transporter activity
KV238_RS00435	COG1028	Short-chain dehydrogenase reductase Sdr
KV238_RS00445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KV238_RS00450	COG0183	Belongs to the thiolase family
KV238_RS00455	COG0583	DNA-binding transcription factor activity
KV238_RS00465	COG1131	(ABC) transporter
KV238_RS00485	COG1136	(ABC) transporter
KV238_RS00490	COG1770	oligopeptidase
KV238_RS00520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KV238_RS00535	COG1573	uracil-dna glycosylase
KV238_RS00540	COG1702	phosphate starvation-inducible protein PhoH
KV238_RS00575	COG0444	Belongs to the ABC transporter superfamily
KV238_RS00580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KV238_RS00585	COG0601	transmembrane transport
KV238_RS00590	COG0747	negative chemotaxis
KV238_RS00655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KV238_RS00675	COG0673	inositol 2-dehydrogenase activity
KV238_RS00685	COG1028	Short-chain dehydrogenase reductase Sdr
KV238_RS00700	COG1376	ErfK ybiS ycfS ynhG family protein
KV238_RS00715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KV238_RS00740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KV238_RS00740	COG1605	Chorismate mutase
KV238_RS00745	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KV238_RS00760	COG3250	beta-galactosidase activity
KV238_RS00765	COG4753	response regulator
KV238_RS00765	COG2207	Transcriptional regulator
KV238_RS00770	COG2972	Histidine kinase
KV238_RS00780	COG1653	transport
KV238_RS00785	COG0395	ABC-type sugar transport system, permease component
KV238_RS00790	COG1175	transmembrane transport
KV238_RS00795	COG1940	carbohydrate kinase activity
KV238_RS00810	COG2188	Transcriptional regulator
KV238_RS00820	COG0383	alpha-mannosidase activity
KV238_RS00825	COG1136	(ABC) transporter
KV238_RS00885	COG2274	protein secretion by the type I secretion system
KV238_RS00900	COG3290	protein histidine kinase activity
KV238_RS01005	COG1040	competence protein
KV238_RS01010	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KV238_RS01015	COG1739	Uncharacterized protein family UPF0029
KV238_RS01025	COG1098	S1 RNA binding domain
KV238_RS01035	COG2197	response regulator
KV238_RS01040	COG4585	Histidine kinase
KV238_RS01050	COG2815	serine threonine protein kinase
KV238_RS01050	COG0515	serine threonine protein kinase
KV238_RS01060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KV238_RS01060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KV238_RS01065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KV238_RS01070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KV238_RS01090	COG1854	S-ribosylhomocysteine lyase activity
KV238_RS01100	COG0116	Belongs to the methyltransferase superfamily
KV238_RS01115	COG4474	Belongs to the UPF0398 family
KV238_RS01125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KV238_RS01130	COG3579	cysteine-type endopeptidase activity
KV238_RS01140	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KV238_RS01145	COG1113	amino acid transport
KV238_RS01150	COG0492	ferredoxin-NADP+ reductase activity
KV238_RS01160	COG1126	abc transporter atp-binding protein
KV238_RS01170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV238_RS01180	COG0513	Belongs to the DEAD box helicase family
KV238_RS01190	COG0768	penicillin binding
KV238_RS01230	COG1131	(ABC) transporter
KV238_RS01290	COG1774	PSP1 C-terminal conserved region
KV238_RS01295	COG0470	DNA polymerase III
KV238_RS01305	COG4471	UPF0298 protein
KV238_RS01325	COG2244	polysaccharide biosynthetic process
KV238_RS01335	COG1120	ATPase activity
KV238_RS01340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KV238_RS01345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV238_RS01350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KV238_RS01365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KV238_RS01370	COG1253	flavin adenine dinucleotide binding
KV238_RS01375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KV238_RS01380	COG3231	kanamycin kinase activity
KV238_RS01385	COG1242	4 iron, 4 sulfur cluster binding
KV238_RS01390	COG0671	phosphoesterase, PA-phosphatase related
KV238_RS01395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KV238_RS01470	COG1187	pseudouridine synthase activity
KV238_RS01480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KV238_RS01525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KV238_RS01530	COG1254	Belongs to the acylphosphatase family
KV238_RS01545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KV238_RS01575	COG1484	DNA-dependent DNA replication
KV238_RS01590	COG5002	protein histidine kinase activity
KV238_RS01595	COG0745	RESPONSE REGULATOR receiver
KV238_RS01610	COG1704	LemA family
KV238_RS01620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KV238_RS01625	COG0569	domain protein
KV238_RS01630	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KV238_RS01635	COG1114	Component of the transport system for branched-chain amino acids
KV238_RS01655	COG1464	Belongs to the NlpA lipoprotein family
KV238_RS01660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV238_RS01670	COG0789	Transcriptional regulator
KV238_RS01680	COG2226	methyltransferase
KV238_RS01685	COG0799	negative regulation of ribosome biogenesis
KV238_RS01690	COG1713	HD superfamily hydrolase involved in NAD metabolism
KV238_RS01695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KV238_RS01700	COG1534	Rna-binding protein
KV238_RS01705	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KV238_RS01710	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KV238_RS01825	COG0444	Belongs to the ABC transporter superfamily
KV238_RS01830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KV238_RS01835	COG0601	transmembrane transport
KV238_RS01840	COG4166	transmembrane transport
KV238_RS01845	COG1686	Belongs to the peptidase S11 family
KV238_RS01850	COG1686	Belongs to the peptidase S11 family
KV238_RS01860	COG0719	Fe-S assembly protein
KV238_RS01870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KV238_RS01875	COG0719	Fe-S assembly protein
KV238_RS01885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KV238_RS01900	COG0765	amino acid transport
KV238_RS01905	COG1126	abc transporter atp-binding protein
KV238_RS01940	COG0191	fructose-bisphosphate aldolase activity
KV238_RS01955	COG0504	CTP synthase activity
KV238_RS01970	COG0366	Alpha amylase catalytic
KV238_RS01975	COG0668	transmembrane transport
KV238_RS01985	COG4720	Psort location CytoplasmicMembrane, score
KV238_RS01990	COG0351	phosphomethylpyrimidine kinase
KV238_RS01990	COG0352	thiamine-phosphate diphosphorylase activity
KV238_RS02000	COG0527	aspartate kinase activity
KV238_RS02045	COG0803	Belongs to the bacterial solute-binding protein 9 family
KV238_RS02055	COG1597	lipid kinase activity
KV238_RS02060	COG1609	Transcriptional regulator
KV238_RS02065	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KV238_RS02070	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KV238_RS02075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KV238_RS02080	COG2017	converts alpha-aldose to the beta-anomer
KV238_RS02125	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KV238_RS02130	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KV238_RS02145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KV238_RS02155	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KV238_RS02165	COG1045	serine acetyltransferase
KV238_RS02200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KV238_RS02205	COG1846	Transcriptional regulator
KV238_RS02220	COG0442	prolyl-tRNA aminoacylation
KV238_RS02230	COG4589	Belongs to the CDS family
KV238_RS02240	COG1862	Preprotein translocase
KV238_RS02255	COG3842	ATPase activity
KV238_RS02310	COG1263	PTS System
KV238_RS02310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV238_RS02310	COG2190	(PTS) system
KV238_RS02315	COG1609	Transcriptional regulator
KV238_RS02320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KV238_RS02325	COG2264	protein methyltransferase activity
KV238_RS02345	COG3732	PTS system glucitol sorbitol-specific
KV238_RS02350	COG3730	PTS system glucitol sorbitol-specific
KV238_RS02360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV238_RS02360	COG3711	transcriptional antiterminator
KV238_RS02390	COG1215	transferase activity, transferring glycosyl groups
KV238_RS02415	COG1234	tRNA 3'-trailer cleavage
KV238_RS02420	COG1268	BioY protein
KV238_RS02475	COG1832	CoA-binding protein
KV238_RS02480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KV238_RS02480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KV238_RS02490	COG3448	diguanylate cyclase activity
KV238_RS02490	COG4175	Glycine betaine
KV238_RS02510	COG3623	hexulose-6-phosphate isomerase
KV238_RS02530	COG3037	sugar-specific permease SgaT UlaA
KV238_RS02570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KV238_RS02590	COG0564	pseudouridine synthase activity
KV238_RS02610	COG1116	anion transmembrane transporter activity
KV238_RS02630	COG1396	sequence-specific DNA binding
KV238_RS02635	COG1051	belongs to the nudix hydrolase family
KV238_RS02695	COG4463	regulation of RNA biosynthetic process
KV238_RS02715	COG0450	alkyl hydroperoxide reductase
KV238_RS02730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KV238_RS02735	COG3590	peptidase
KV238_RS02740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KV238_RS02745	COG3959	Transketolase, thiamine diphosphate binding domain
KV238_RS02760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV238_RS02800	COG4537	Required for transformation and DNA binding
KV238_RS02805	COG1459	type II secretion system
KV238_RS02810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KV238_RS02815	COG1136	(ABC) transporter
KV238_RS02840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KV238_RS02850	COG4499	WXG100 protein secretion system (Wss), protein YukC
KV238_RS02850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KV238_RS02860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KV238_RS02865	COG1121	(ABC) transporter
KV238_RS02880	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KV238_RS03035	COG0563	adenylate kinase activity
KV238_RS03040	COG0201	protein transport
KV238_RS03130	COG0089	rRNA binding
KV238_RS03135	COG0088	Forms part of the polypeptide exit tunnel
KV238_RS03145	COG0051	transcription antitermination factor activity, RNA binding
KV238_RS03155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KV238_RS03165	COG1064	alcohol dehydrogenase
KV238_RS03170	COG1063	alcohol dehydrogenase
KV238_RS03175	COG1454	alcohol dehydrogenase
KV238_RS03175	COG1012	belongs to the aldehyde dehydrogenase family
KV238_RS03190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KV238_RS03205	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KV238_RS03220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KV238_RS03225	COG0151	Belongs to the GarS family
KV238_RS03240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KV238_RS03265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KV238_RS03270	COG0416	fatty acid biosynthetic process
KV238_RS03285	COG3942	CHAP domain
KV238_RS03405	COG0531	amino acid
KV238_RS03410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KV238_RS03435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KV238_RS03440	COG2244	polysaccharide biosynthetic process
KV238_RS03445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KV238_RS03455	COG0012	GTP binding
KV238_RS03470	COG0592	DNA-directed DNA polymerase activity
KV238_RS03480	COG1475	DNA binding
KV238_RS03485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KV238_RS03515	COG0488	(ABC) transporter
KV238_RS03520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV238_RS03535	COG0517	IMP dehydrogenase activity
KV238_RS03535	COG0516	GMP reductase activity
KV238_RS03575	COG2501	S4 domain
KV238_RS03585	COG0612	Peptidase, M16
KV238_RS03595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KV238_RS03625	COG1760	l-serine dehydratase
KV238_RS03630	COG1760	l-serine dehydratase
KV238_RS03640	COG2816	NAD+ diphosphatase activity
KV238_RS03660	COG0305	Participates in initiation and elongation during chromosome replication
KV238_RS03700	COG1511	domain protein
KV238_RS03720	COG0494	nUDIX hydrolase
KV238_RS03740	COG0577	efflux transmembrane transporter activity
KV238_RS03740	COG1136	(ABC) transporter
KV238_RS03755	COG2197	response regulator
KV238_RS03780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KV238_RS03785	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KV238_RS03795	COG0124	histidyl-tRNA synthetase
KV238_RS03805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV238_RS03810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV238_RS03815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KV238_RS03820	COG0488	(ABC) transporter
KV238_RS03825	COG0018	arginyl-trna synthetase
KV238_RS03830	COG1438	arginine binding
KV238_RS03850	COG2814	Major facilitator Superfamily
KV238_RS03855	COG0632	four-way junction helicase activity
KV238_RS03860	COG0519	Catalyzes the synthesis of GMP from XMP
KV238_RS03890	COG1393	Belongs to the ArsC family
KV238_RS03900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KV238_RS03915	COG1328	CTP reductase activity
KV238_RS03935	COG0602	queuosine metabolic process
KV238_RS03965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KV238_RS03970	COG1363	Peptidase, m42
KV238_RS03980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV238_RS03985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KV238_RS04005	COG4120	Belongs to the binding-protein-dependent transport system permease family
KV238_RS04020	COG1428	Deoxynucleoside kinase
KV238_RS04025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KV238_RS04095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KV238_RS04100	COG1349	DNA-binding transcription factor activity
KV238_RS04110	COG1447	Phosphotransferase system cellobiose-specific component IIA
KV238_RS04115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV238_RS04120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV238_RS04125	COG1882	Formate acetyltransferase
KV238_RS04200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KV238_RS04205	COG0512	Glutamine amidotransferase of anthranilate synthase
KV238_RS04210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KV238_RS04370	COG1396	sequence-specific DNA binding
KV238_RS04375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KV238_RS04470	COG1192	Involved in chromosome partitioning
KV238_RS04525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KV238_RS04530	COG0705	Rhomboid family
KV238_RS04530	COG0457	Tetratricopeptide repeat
KV238_RS04540	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KV238_RS04550	COG1132	(ABC) transporter
KV238_RS04555	COG1132	(ABC) transporter
KV238_RS04565	COG0756	dUTP diphosphatase activity
KV238_RS04615	COG1131	(ABC) transporter
KV238_RS04645	COG1847	R3H domain protein
KV238_RS04690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV238_RS04690	COG1263	PTS System
KV238_RS04690	COG2190	(PTS) system
KV238_RS04695	COG1263	PTS System
KV238_RS04695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV238_RS04695	COG2190	(PTS) system
KV238_RS04715	COG1175	transmembrane transport
KV238_RS04720	COG0395	ABC-type sugar transport system, permease component
KV238_RS04725	COG2731	YhcH YjgK YiaL family protein
KV238_RS04735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KV238_RS04745	COG3458	cephalosporin-C deacetylase activity
KV238_RS04750	COG1737	Transcriptional regulator
KV238_RS04760	COG0084	hydrolase, TatD family'
KV238_RS04785	COG1564	THIamine pyrophosphokinase
KV238_RS04800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KV238_RS04830	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KV238_RS04835	COG0126	phosphoglycerate kinase activity
KV238_RS04845	COG0789	Transcriptional regulator
KV238_RS04850	COG0174	glutamine synthetase
KV238_RS04855	COG4166	transmembrane transport
KV238_RS04860	COG0601	transmembrane transport
KV238_RS04865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KV238_RS04870	COG0444	Belongs to the ABC transporter superfamily
KV238_RS04875	COG4608	Belongs to the ABC transporter superfamily
KV238_RS04885	COG5503	Protein of unknown function (DUF1447)
KV238_RS04890	COG1214	PFAM Peptidase M22, glycoprotease
KV238_RS04905	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KV238_RS04915	COG2081	HI0933 family
KV238_RS04930	COG0789	Transcriptional regulator
KV238_RS04950	COG5002	protein histidine kinase activity
KV238_RS04990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KV238_RS04995	COG2814	Major facilitator Superfamily
KV238_RS05005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KV238_RS05020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KV238_RS05030	COG1882	Formate acetyltransferase
KV238_RS05045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KV238_RS05050	COG0681	Belongs to the peptidase S26 family
KV238_RS05065	COG1286	toxin biosynthetic process
KV238_RS05075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KV238_RS05080	COG3118	belongs to the thioredoxin family
KV238_RS05100	COG1194	a g-specific adenine glycosylase
KV238_RS05150	COG0006	proline dipeptidase activity
KV238_RS05155	COG2131	deaminase
KV238_RS05195	COG1609	Transcriptional regulator
KV238_RS05200	COG1621	beta-fructofuranosidase activity
KV238_RS05205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV238_RS05205	COG1263	PTS System
KV238_RS05205	COG2190	(PTS) system
KV238_RS05215	COG1940	carbohydrate kinase activity
KV238_RS05220	COG1482	cell wall glycoprotein biosynthetic process
KV238_RS05225	COG0653	protein targeting
KV238_RS05240	COG1388	LysM domain
KV238_RS05240	COG3942	CHAP domain
KV238_RS05265	COG1120	ATPase activity
KV238_RS05270	COG4988	ABC transporter
KV238_RS05275	COG1132	(ABC) transporter
KV238_RS05290	COG1129	ABC transporter
KV238_RS05295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KV238_RS05300	COG0252	asparaginase activity
KV238_RS05305	COG0561	phosphatase activity
KV238_RS05315	COG0436	Aminotransferase
KV238_RS05320	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KV238_RS05325	COG1335	isochorismatase
KV238_RS05335	COG0154	amidase activity
KV238_RS05345	COG0697	spore germination
KV238_RS05350	COG2261	transglycosylase associated protein
KV238_RS05360	COG3830	Belongs to the UPF0237 family
KV238_RS05370	COG0588	phosphoglycerate mutase activity
KV238_RS05375	COG1876	peptidase activity
KV238_RS05405	COG1024	Enoyl-CoA hydratase
KV238_RS05415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KV238_RS05425	COG2070	2-Nitropropane dioxygenase
KV238_RS05430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KV238_RS05435	COG1028	Short-chain dehydrogenase reductase Sdr
KV238_RS05440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KV238_RS05455	COG0439	Biotin carboxylase
KV238_RS05485	COG3716	PTS system mannose fructose sorbose family IID component
KV238_RS05490	COG3715	PTS system
KV238_RS05500	COG0561	phosphatase activity
KV238_RS05505	COG2252	PERMEase
KV238_RS05510	COG0802	atpase or kinase
KV238_RS05520	COG1316	TRANSCRIPTIONal
KV238_RS05530	COG0537	adenosine 5'-monophosphoramidase activity
KV238_RS05540	COG1131	(ABC) transporter
KV238_RS05545	COG4473	ABC transporter
KV238_RS05570	COG0195	Participates in both transcription termination and antitermination
KV238_RS05575	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KV238_RS05605	COG2217	Heavy metal translocating P-type atpase
KV238_RS05625	COG0698	ribose 5-phosphate isomerase
KV238_RS05630	COG0698	ribose 5-phosphate isomerase
KV238_RS05645	COG3711	transcriptional antiterminator
KV238_RS05650	COG1447	Phosphotransferase system cellobiose-specific component IIA
KV238_RS05655	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV238_RS05655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV238_RS05660	COG2723	6-phospho-beta-galactosidase activity
KV238_RS05670	COG2860	membrane
KV238_RS05675	COG0561	phosphatase activity
KV238_RS05690	COG1609	Transcriptional regulator
KV238_RS05695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KV238_RS05700	COG1869	D-ribose catabolic process
KV238_RS05710	COG1172	Belongs to the binding-protein-dependent transport system permease family
KV238_RS05715	COG1879	ABC-type sugar transport system periplasmic component
KV238_RS05725	COG1283	sodium-dependent phosphate transmembrane transporter activity
KV238_RS05735	COG0656	L-ascorbic acid biosynthetic process
KV238_RS05745	COG1755	Isoprenylcysteine carboxyl methyltransferase
KV238_RS05795	COG1131	(ABC) transporter
KV238_RS05840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KV238_RS05845	COG1393	Belongs to the ArsC family
KV238_RS05850	COG0708	Exodeoxyribonuclease III
KV238_RS05905	COG2274	protein secretion by the type I secretion system
KV238_RS05910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KV238_RS05935	COG1114	Component of the transport system for branched-chain amino acids
KV238_RS06065	COG1518	maintenance of DNA repeat elements
KV238_RS06070	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KV238_RS06080	COG0785	Cytochrome C biogenesis protein
KV238_RS06085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KV238_RS06095	COG2207	Transcriptional regulator
KV238_RS06095	COG4753	response regulator
KV238_RS06100	COG2972	Histidine kinase
KV238_RS06105	COG2315	Protein conserved in bacteria
KV238_RS06130	COG2235	arginine
KV238_RS06145	COG1288	antiporter activity
KV238_RS06150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KV238_RS06155	COG0549	Belongs to the carbamate kinase family
KV238_RS06165	COG0742	ribosomal rna small subunit methyltransferase
KV238_RS06170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KV238_RS06175	COG3480	Lon protease (S16) C-terminal proteolytic domain
KV238_RS06180	COG4470	Protein conserved in bacteria
KV238_RS06190	COG1131	(ABC) transporter
KV238_RS06200	COG0842	Transport permease protein
KV238_RS06205	COG4585	Histidine kinase
KV238_RS06210	COG2197	response regulator
KV238_RS06220	COG0783	Belongs to the Dps family
KV238_RS06225	COG4483	Protein conserved in bacteria
KV238_RS06230	COG1940	carbohydrate kinase activity
KV238_RS06235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KV238_RS06240	COG1217	gtp-binding protein TYPA
KV238_RS06265	COG0849	cell division
KV238_RS06275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KV238_RS06295	COG3599	regulation of cell shape
KV238_RS06310	COG0494	nUDIX hydrolase
KV238_RS06315	COG0542	response to heat
KV238_RS06320	COG4703	Protein of unknown function (DUF1797)
KV238_RS06330	COG0765	amino acid transport
KV238_RS06335	COG1126	abc transporter atp-binding protein
KV238_RS06340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KV238_RS06350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KV238_RS06370	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KV238_RS06375	COG1438	arginine binding
KV238_RS06380	COG0497	DNA recombination
KV238_RS06395	COG2755	lipolytic protein G-D-S-L family
KV238_RS06400	COG4698	Protein conserved in bacteria
KV238_RS06420	COG1396	sequence-specific DNA binding
KV238_RS06440	COG1827	regulation of RNA biosynthetic process
KV238_RS06450	COG2116	formate transmembrane transporter activity
KV238_RS06455	COG0768	penicillin binding
KV238_RS06470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KV238_RS06485	COG0513	Belongs to the DEAD box helicase family
KV238_RS06490	COG3158	transport of potassium into the cell
KV238_RS06505	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KV238_RS06510	COG0204	Acyl-transferase
KV238_RS06520	COG0658	competence protein
KV238_RS06520	COG2333	competence protein COMEC
KV238_RS06555	COG0363	glucosamine-6-phosphate deaminase activity
KV238_RS06560	COG1187	pseudouridine synthase activity
KV238_RS06585	COG0546	phosphoglycolate phosphatase activity
KV238_RS06590	COG4122	O-methyltransferase activity
KV238_RS06615	COG0726	polysaccharide deacetylase
KV238_RS06640	COG1956	GAF domain-containing protein
KV238_RS06645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KV238_RS06655	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KV238_RS06655	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KV238_RS06675	COG2211	Major facilitator Superfamily
KV238_RS06685	COG3250	beta-galactosidase activity
KV238_RS06690	COG2186	Transcriptional regulator
KV238_RS06695	COG0800	Aldolase
KV238_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
KV238_RS06735	COG4109	DRTGG domain
KV238_RS06740	COG0024	Methionine aminopeptidase
KV238_RS06760	COG1316	TRANSCRIPTIONal
KV238_RS06865	COG5290	Psort location Cytoplasmic, score
KV238_RS06880	COG1373	ATPase (AAA superfamily
KV238_RS06890	COG0588	phosphoglycerate mutase activity
KV238_RS06900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KV238_RS06905	COG3859	Proton-coupled thiamine transporter YuaJ
KV238_RS06930	COG0386	Belongs to the glutathione peroxidase family
KV238_RS06935	COG1164	Oligoendopeptidase f
KV238_RS06945	COG0772	Belongs to the SEDS family
KV238_RS06955	COG1131	(ABC) transporter
KV238_RS06970	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KV238_RS06985	COG2884	Cell division ATP-binding protein ftsE
KV238_RS06990	COG2177	Part of the ABC transporter FtsEX involved in
KV238_RS07000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KV238_RS07000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KV238_RS07000	COG1199	ATP-dependent helicase activity
KV238_RS07000	COG1199	ATP-dependent helicase activity
KV238_RS07010	COG0436	Aminotransferase
KV238_RS07015	COG0017	Asparaginyl-tRNA synthetase
KV238_RS07050	COG2188	Transcriptional regulator
KV238_RS07055	COG2222	sugar isomerase
KV238_RS07060	COG3684	Belongs to the aldolase LacD family
KV238_RS07065	COG2188	Transcriptional regulator
KV238_RS07075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV238_RS07075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV238_RS07080	COG3715	PTS system
KV238_RS07085	COG3716	PTS system mannose fructose sorbose family IID component
KV238_RS07100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KV238_RS07105	COG2153	protein acetylation
KV238_RS07115	COG0716	FMN binding
KV238_RS07125	COG0038	chloride channel
KV238_RS07145	COG1476	TRANSCRIPTIONal
KV238_RS07165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KV238_RS07170	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KV238_RS07175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV238_RS07185	COG1012	belongs to the aldehyde dehydrogenase family
KV238_RS07190	COG0772	Belongs to the SEDS family
KV238_RS07265	COG4708	membrane
KV238_RS07275	COG1597	lipid kinase activity
KV238_RS07280	COG1523	belongs to the glycosyl hydrolase 13 family
KV238_RS07285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KV238_RS07290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KV238_RS07295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KV238_RS07305	COG0058	SHG alpha-glucan phosphorylase activity
KV238_RS07385	COG0577	efflux transmembrane transporter activity
KV238_RS07450	COG1523	belongs to the glycosyl hydrolase 13 family
KV238_RS07455	COG1595	DNA-templated transcription, initiation
KV238_RS07495	COG1074	ATP-dependent DNA helicase activity
KV238_RS07500	COG0436	Aminotransferase
KV238_RS07505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV238_RS07515	COG1970	mechanosensitive ion channel activity
KV238_RS07520	COG0358	DNA primase activity
KV238_RS07525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KV238_RS07530	COG2151	metal-sulfur cluster biosynthetic enzyme
KV238_RS07535	COG1091	dTDP-4-dehydrorhamnose reductase activity
KV238_RS07545	COG0463	Glycosyl transferase, family 2
KV238_RS07570	COG0463	Glycosyl transferase, family 2
KV238_RS07590	COG0297	glycogen (starch) synthase activity
KV238_RS07595	COG1368	sulfuric ester hydrolase activity
KV238_RS07600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KV238_RS07650	COG1368	sulfuric ester hydrolase activity
KV238_RS07655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KV238_RS07660	COG0710	3-dehydroquinate dehydratase activity
KV238_RS07670	COG3679	Belongs to the UPF0342 family
KV238_RS07675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KV238_RS07685	COG1104	cysteine desulfurase activity
KV238_RS07745	COG3561	AntA/AntB antirepressor
KV238_RS07820	COG0582	viral genome integration into host DNA
KV238_RS07855	COG0740	serine-type endopeptidase activity
KV238_RS07955	COG0860	N-Acetylmuramoyl-L-alanine amidase
KV238_RS07955	COG1388	LysM domain
KV238_RS07990	COG1131	(ABC) transporter
KV238_RS07995	COG1725	Transcriptional regulator
KV238_RS08010	COG0469	pyruvate kinase activity
KV238_RS08025	COG2824	Alkylphosphonate utilization operon protein PhnA
KV238_RS08030	COG0765	amino acid transport
KV238_RS08035	COG1126	abc transporter atp-binding protein
KV238_RS08040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV238_RS08045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KV238_RS08050	COG1115	amino acid carrier protein
KV238_RS08100	COG1136	(ABC) transporter
KV238_RS08100	COG4591	ABC-type transport system involved in lipoprotein release permease component
KV238_RS08130	COG0196	riboflavin kinase activity
KV238_RS08145	COG0483	inositol monophosphate 1-phosphatase activity
KV238_RS08150	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KV238_RS08150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KV238_RS08160	COG0573	inorganic phosphate transmembrane transporter activity
KV238_RS08165	COG0581	inorganic phosphate transmembrane transporter activity
KV238_RS08180	COG0704	Plays a role in the regulation of phosphate uptake
KV238_RS08190	COG0745	RESPONSE REGULATOR receiver
KV238_RS08195	COG5002	protein histidine kinase activity
KV238_RS08270	COG2813	Specifically methylates the guanine in position
KV238_RS08275	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KV238_RS08290	COG1744	ABC transporter substrate-binding protein PnrA-like
KV238_RS08295	COG3845	ABC transporter
KV238_RS08300	COG4603	Belongs to the binding-protein-dependent transport system permease family
KV238_RS08305	COG1079	Belongs to the binding-protein-dependent transport system permease family
KV238_RS08310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KV238_RS08315	COG4684	Psort location CytoplasmicMembrane, score
KV238_RS08320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KV238_RS08330	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KV238_RS08345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KV238_RS08350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KV238_RS08355	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KV238_RS08355	COG1328	CTP reductase activity
KV238_RS08360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KV238_RS08375	COG0488	(ABC) transporter
KV238_RS08385	COG1597	lipid kinase activity
KV238_RS08390	COG1272	protein, Hemolysin III
KV238_RS08400	COG2226	methyltransferase
KV238_RS08425	COG1131	(ABC) transporter
KV238_RS08455	COG1136	(ABC) transporter
KV238_RS08455	COG0577	efflux transmembrane transporter activity
KV238_RS08460	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KV238_RS08470	COG0758	DNA mediated transformation
KV238_RS08475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KV238_RS08490	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KV238_RS08495	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KV238_RS08505	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KV238_RS08515	COG2851	Citrate transporter
KV238_RS08525	COG0511	ligase activity, forming carbon-carbon bonds
KV238_RS08530	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KV238_RS08565	COG1136	(ABC) transporter
KV238_RS08570	COG0577	efflux transmembrane transporter activity
KV238_RS08575	COG0745	RESPONSE REGULATOR receiver
KV238_RS08580	COG5002	protein histidine kinase activity
KV238_RS08585	COG4974	Belongs to the 'phage' integrase family
KV238_RS08595	COG1396	sequence-specific DNA binding
KV238_RS08620	COG2188	Transcriptional regulator
KV238_RS08630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KV238_RS08650	COG0803	Belongs to the bacterial solute-binding protein 9 family
KV238_RS08655	COG0346	lactoylglutathione lyase activity
KV238_RS08660	COG3764	Sortase (surface protein transpeptidase)
KV238_RS08690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KV238_RS08695	COG1247	-acetyltransferase
KV238_RS08700	COG0009	L-threonylcarbamoyladenylate synthase
KV238_RS08705	COG2890	protein-(glutamine-N5) methyltransferase activity
KV238_RS08720	COG1942	4-Oxalocrotonate Tautomerase
KV238_RS08730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KV238_RS08735	COG0516	GMP reductase activity
KV238_RS08740	COG1174	glycine betaine transport
KV238_RS08755	COG4221	oxidoreductase activity
KV238_RS08760	COG0280	phosphate acetyltransferase
KV238_RS08765	COG0564	pseudouridine synthase activity
KV238_RS08775	COG2357	RelA SpoT domain protein
KV238_RS08790	COG1104	cysteine desulfurase activity
KV238_RS08805	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KV238_RS08815	COG0628	permease
KV238_RS08835	COG1177	transmembrane transport
KV238_RS08840	COG1176	ABC-type spermidine putrescine transport system, permease component I
KV238_RS08850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KV238_RS08855	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KV238_RS08870	COG0302	gtp cyclohydrolase
KV238_RS08875	COG0285	dihydrofolate synthase activity
KV238_RS08885	COG0460	homoserine dehydrogenase
KV238_RS08890	COG0726	polysaccharide deacetylase
KV238_RS08915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KV238_RS08930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KV238_RS08940	COG3425	synthase
KV238_RS08970	COG1132	(ABC) transporter
KV238_RS08975	COG1132	(ABC) transporter
KV238_RS08980	COG0737	Belongs to the 5'-nucleotidase family
KV238_RS08985	COG0242	peptide deformylase activity
KV238_RS08990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KV238_RS09005	COG0488	(ABC) transporter
KV238_RS09025	COG1388	LysM domain
KV238_RS09025	COG1705	Flagellar rod assembly protein muramidase FlgJ
KV238_RS09045	COG1476	TRANSCRIPTIONal
KV238_RS09050	COG1388	LysM domain
KV238_RS09050	COG1705	Flagellar rod assembly protein muramidase FlgJ
KV238_RS09055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KV238_RS09055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KV238_RS09055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV238_RS09060	COG1105	Belongs to the carbohydrate kinase PfkB family
KV238_RS09065	COG1349	DNA-binding transcription factor activity
KV238_RS09090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KV238_RS09105	COG1837	Belongs to the UPF0109 family
KV238_RS09120	COG0577	efflux transmembrane transporter activity
KV238_RS09125	COG1136	(ABC) transporter
KV238_RS09130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KV238_RS09135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KV238_RS09165	COG0564	pseudouridine synthase activity
KV238_RS09180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KV238_RS09230	COG1705	Flagellar rod assembly protein muramidase FlgJ
KV238_RS09330	COG0740	serine-type endopeptidase activity
KV238_RS09365	COG0582	viral genome integration into host DNA
KV238_RS09470	COG3561	AntA/AntB antirepressor
KV238_RS09485	COG1396	sequence-specific DNA binding
KV238_RS09515	COG0539	negative regulation of cytoplasmic translation
KV238_RS09535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KV238_RS09550	COG0187	DNA topoisomerase II activity
KV238_RS09575	COG0765	amino acid transport
KV238_RS09580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KV238_RS09595	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KV238_RS09600	COG0284	orotidine-5'-phosphate decarboxylase activity
KV238_RS09610	COG0583	DNA-binding transcription factor activity
KV238_RS09635	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KV238_RS09685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KV238_RS09695	COG0322	excinuclease ABC activity
KV238_RS09705	COG2207	Transcriptional regulator
KV238_RS09705	COG4753	response regulator
KV238_RS09710	COG2972	Histidine kinase
KV238_RS09715	COG3716	PTS system mannose fructose sorbose family IID component
KV238_RS09720	COG3715	PTS system
KV238_RS09745	COG0481	GTPase activity
KV238_RS09845	COG0745	RESPONSE REGULATOR receiver
KV238_RS09850	COG2205	protein histidine kinase activity
KV238_RS09940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KV238_RS09960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KV238_RS09965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KV238_RS09970	COG3442	glutamine amidotransferase
KV238_RS09975	COG0095	Lipoate-protein ligase
KV238_RS09985	COG0508	dehydrogenase complex catalyzes the overall conversion of
KV238_RS09990	COG0508	dehydrogenase complex catalyzes the overall conversion of
KV238_RS09990	COG0022	dehydrogenase e1 component
KV238_RS09995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KV238_RS10000	COG0488	(ABC) transporter
KV238_RS10030	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KV238_RS10035	COG0457	Tetratricopeptide repeat
KV238_RS10040	COG0628	permease
KV238_RS10045	COG1051	belongs to the nudix hydrolase family
KV238_RS10050	COG1088	dTDP-glucose 4,6-dehydratase activity
KV238_RS10060	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KV238_RS10065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KV238_RS10075	COG2384	SAM-dependent methyltransferase
KV238_RS10080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KV238_RS10100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KV238_RS10100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KV238_RS10105	COG0300	oxidoreductase activity
KV238_RS10115	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KV238_RS10120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KV238_RS10125	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KV238_RS10140	COG0058	SHG alpha-glucan phosphorylase activity
KV238_RS10145	COG1640	4-alpha-glucanotransferase
KV238_RS10150	COG1609	Transcriptional regulator
KV238_RS10160	COG1175	transmembrane transport
KV238_RS10165	COG3833	ABC-type maltose transport systems, permease component
KV238_RS10175	COG3833	ABC-type maltose transport systems, permease component
KV238_RS10180	COG1175	transmembrane transport
KV238_RS10190	COG0366	Alpha amylase catalytic
KV238_RS10195	COG2182	Extracellular solute-binding protein
KV238_RS10200	COG0657	acetylesterase activity
KV238_RS10205	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KV238_RS10215	COG1696	Membrane protein involved in D-alanine export
KV238_RS10230	COG0556	nucleotide-excision repair
KV238_RS10235	COG0765	amino acid transport
KV238_RS10240	COG1126	abc transporter atp-binding protein
KV238_RS10250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KV238_RS10260	COG1447	Phosphotransferase system cellobiose-specific component IIA
KV238_RS10270	COG3711	transcriptional antiterminator
KV238_RS10270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KV238_RS10280	COG2723	6-phospho-beta-galactosidase activity
KV238_RS10295	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KV238_RS10305	COG2309	aminopeptidase activity
KV238_RS10310	COG1187	pseudouridine synthase activity
KV238_RS10320	COG2814	Major facilitator Superfamily
KV238_RS10325	COG4868	Belongs to the UPF0371 family
KV238_RS10355	COG0800	Aldolase
KV238_RS10360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KV238_RS10370	COG1028	Short-chain dehydrogenase reductase Sdr
KV238_RS10385	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KV238_RS10390	COG3715	PTS system
KV238_RS10395	COG3716	PTS system mannose fructose sorbose family IID component
KV238_RS10400	COG1609	Transcriptional regulator
KV238_RS10440	COG1078	dGTPase activity
KV238_RS10480	COG1191	sigma factor activity
KV238_RS10545	COG2814	Major facilitator Superfamily
KV238_RS10560	COG4443	Transcriptional Coactivator p15 (PC4)
KV238_RS10570	COG0826	peptidase U32
KV238_RS10615	COG2183	response to ionizing radiation
KV238_RS10625	COG0704	Plays a role in the regulation of phosphate uptake
KV238_RS10630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KV238_RS10640	COG0573	inorganic phosphate transmembrane transporter activity
KV238_RS10645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KV238_RS10650	COG5002	protein histidine kinase activity
KV238_RS10655	COG0745	RESPONSE REGULATOR receiver
KV238_RS10665	COG0701	Predicted permease
KV238_RS10670	COG3689	TIGRFAM TIGR03943 family protein