locus-tag	class	description
GO596_RS00005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GO596_RS00010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO596_RS00015	COG4122	O-methyltransferase activity
GO596_RS00020	COG0546	phosphoglycolate phosphatase activity
GO596_RS00040	COG1187	pseudouridine synthase activity
GO596_RS00045	COG0363	glucosamine-6-phosphate deaminase activity
GO596_RS00055	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GO596_RS00060	COG0217	transcriptional regulatory protein
GO596_RS00065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GO596_RS00075	COG2333	competence protein COMEC
GO596_RS00075	COG0658	competence protein
GO596_RS00080	COG1596	polysaccharide export
GO596_RS00080	COG1555	photosystem II stabilization
GO596_RS00085	COG0204	Acyl-transferase
GO596_RS00090	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GO596_RS00105	COG2169	Transcriptional regulator
GO596_RS00120	COG0513	Belongs to the DEAD box helicase family
GO596_RS00135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GO596_RS00145	COG1181	Belongs to the D-alanine--D-alanine ligase family
GO596_RS00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GO596_RS00155	COG0768	penicillin binding
GO596_RS00165	COG1827	regulation of RNA biosynthetic process
GO596_RS00170	COG0588	phosphoglycerate mutase activity
GO596_RS00175	COG2217	Heavy metal translocating P-type atpase
GO596_RS00180	COG0640	Transcriptional regulator
GO596_RS00185	COG0167	dihydroorotate dehydrogenase activity
GO596_RS00190	COG3104	oligopeptide transport
GO596_RS00205	COG4698	Protein conserved in bacteria
GO596_RS00210	COG2755	lipolytic protein G-D-S-L family
GO596_RS00215	COG1307	EDD domain protein, DegV family
GO596_RS00220	COG0497	DNA recombination
GO596_RS00225	COG1438	arginine binding
GO596_RS00230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GO596_RS00260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GO596_RS00265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GO596_RS00275	COG1918	ferrous iron import across plasma membrane
GO596_RS00275	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GO596_RS00285	COG1126	abc transporter atp-binding protein
GO596_RS00290	COG0765	amino acid transport
GO596_RS00295	COG4703	Protein of unknown function (DUF1797)
GO596_RS00300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GO596_RS00305	COG0542	response to heat
GO596_RS00325	COG3599	regulation of cell shape
GO596_RS00340	COG1799	cell septum assembly
GO596_RS00345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GO596_RS00380	COG1217	gtp-binding protein TYPA
GO596_RS00385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO596_RS00390	COG1940	carbohydrate kinase activity
GO596_RS00400	COG0783	Belongs to the Dps family
GO596_RS00410	COG1914	H( )-stimulated, divalent metal cation uptake system
GO596_RS00415	COG0159	tryptophan synthase activity
GO596_RS00420	COG0133	tryptophan synthase activity
GO596_RS00425	COG0135	phosphoribosylanthranilate isomerase activity
GO596_RS00430	COG0134	indole-3-glycerol-phosphate synthase activity
GO596_RS00440	COG0512	Glutamine amidotransferase of anthranilate synthase
GO596_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO596_RS00455	COG2197	response regulator
GO596_RS00460	COG4585	Histidine kinase
GO596_RS00470	COG1131	(ABC) transporter
GO596_RS00475	COG1132	(ABC) transporter
GO596_RS00480	COG1132	(ABC) transporter
GO596_RS00495	COG4470	Protein conserved in bacteria
GO596_RS00500	COG0737	Belongs to the 5'-nucleotidase family
GO596_RS00510	COG3480	Lon protease (S16) C-terminal proteolytic domain
GO596_RS00515	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GO596_RS00520	COG0742	ribosomal rna small subunit methyltransferase
GO596_RS00575	COG1428	Deoxynucleoside kinase
GO596_RS00590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO596_RS00600	COG2137	regulation of response to DNA damage stimulus
GO596_RS00605	COG3557	Belongs to the UPF0374 family
GO596_RS00675	COG1040	competence protein
GO596_RS00680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GO596_RS00685	COG1739	Uncharacterized protein family UPF0029
GO596_RS00695	COG1098	S1 RNA binding domain
GO596_RS00705	COG2197	response regulator
GO596_RS00710	COG4585	Histidine kinase
GO596_RS00720	COG0515	serine threonine protein kinase
GO596_RS00720	COG2815	serine threonine protein kinase
GO596_RS00730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GO596_RS00730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GO596_RS00740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GO596_RS00760	COG1854	S-ribosylhomocysteine lyase activity
GO596_RS00775	COG0116	Belongs to the methyltransferase superfamily
GO596_RS00785	COG3599	regulation of cell shape
GO596_RS00795	COG3331	DNA recombination
GO596_RS00800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO596_RS00805	COG3579	cysteine-type endopeptidase activity
GO596_RS00810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GO596_RS00815	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GO596_RS00820	COG0492	ferredoxin-NADP+ reductase activity
GO596_RS00830	COG1126	abc transporter atp-binding protein
GO596_RS00835	COG0765	amino acid transport
GO596_RS00845	COG0513	Belongs to the DEAD box helicase family
GO596_RS00855	COG0768	penicillin binding
GO596_RS00865	COG0275	rRNA processing
GO596_RS00870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GO596_RS00875	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GO596_RS00885	COG1131	(ABC) transporter
GO596_RS00920	COG1283	sodium-dependent phosphate transmembrane transporter activity
GO596_RS00945	COG0561	phosphatase activity
GO596_RS00950	COG2860	membrane
GO596_RS00960	COG2217	Heavy metal translocating P-type atpase
GO596_RS00975	COG1611	Belongs to the LOG family
GO596_RS00995	COG1131	(ABC) transporter
GO596_RS01000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GO596_RS01005	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GO596_RS01015	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GO596_RS01020	COG0195	Participates in both transcription termination and antitermination
GO596_RS01040	COG0463	Glycosyl transferase, family 2
GO596_RS01045	COG5001	Diguanylate cyclase
GO596_RS01045	COG3300	MHYT domain
GO596_RS01055	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GO596_RS01065	COG4473	ABC transporter
GO596_RS01070	COG1131	(ABC) transporter
GO596_RS01075	COG0537	adenosine 5'-monophosphoramidase activity
GO596_RS01085	COG1316	TRANSCRIPTIONal
GO596_RS01095	COG0802	atpase or kinase
GO596_RS01100	COG2252	PERMEase
GO596_RS01115	COG0561	phosphatase activity
GO596_RS01125	COG3715	PTS system
GO596_RS01130	COG3716	PTS system mannose fructose sorbose family IID component
GO596_RS01140	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GO596_RS01155	COG0439	Biotin carboxylase
GO596_RS01170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO596_RS01175	COG1028	Short-chain dehydrogenase reductase Sdr
GO596_RS01180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GO596_RS01185	COG2070	2-Nitropropane dioxygenase
GO596_RS01195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GO596_RS01205	COG1024	Enoyl-CoA hydratase
GO596_RS01210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO596_RS01215	COG0527	aspartate kinase activity
GO596_RS01250	COG4608	Belongs to the ABC transporter superfamily
GO596_RS01255	COG0444	Belongs to the ABC transporter superfamily
GO596_RS01260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO596_RS01265	COG0601	transmembrane transport
GO596_RS01270	COG4166	transmembrane transport
GO596_RS01275	COG1686	Belongs to the peptidase S11 family
GO596_RS01290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GO596_RS01295	COG0719	Fe-S assembly protein
GO596_RS01305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GO596_RS01325	COG0765	amino acid transport
GO596_RS01330	COG1126	abc transporter atp-binding protein
GO596_RS01345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GO596_RS01355	COG0440	acetolactate synthase activity
GO596_RS01360	COG0028	Belongs to the TPP enzyme family
GO596_RS01365	COG0129	dihydroxy-acid dehydratase activity
GO596_RS01370	COG1461	Dihydroxyacetone kinase
GO596_RS01380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GO596_RS01390	COG0191	fructose-bisphosphate aldolase activity
GO596_RS01405	COG0504	CTP synthase activity
GO596_RS01420	COG0668	transmembrane transport
GO596_RS01435	COG0351	phosphomethylpyrimidine kinase
GO596_RS01460	COG0443	Heat shock 70 kDa protein
GO596_RS01480	COG1876	peptidase activity
GO596_RS01485	COG0588	phosphoglycerate mutase activity
GO596_RS01490	COG2848	UPF0210 protein
GO596_RS01495	COG3830	Belongs to the UPF0237 family
GO596_RS01535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GO596_RS01560	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GO596_RS01570	COG1045	serine acetyltransferase
GO596_RS01580	COG1185	polyribonucleotide nucleotidyltransferase activity
GO596_RS01590	COG1454	alcohol dehydrogenase
GO596_RS01590	COG1012	belongs to the aldehyde dehydrogenase family
GO596_RS01615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GO596_RS01620	COG1846	Transcriptional regulator
GO596_RS01640	COG4589	Belongs to the CDS family
GO596_RS01645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GO596_RS01650	COG1862	Preprotein translocase
GO596_RS01660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GO596_RS01665	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GO596_RS01670	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GO596_RS01675	COG1609	Transcriptional regulator
GO596_RS01680	COG0366	Alpha amylase catalytic
GO596_RS01685	COG0366	Alpha amylase catalytic
GO596_RS01690	COG0395	ABC-type sugar transport system, permease component
GO596_RS01695	COG1175	transmembrane transport
GO596_RS01700	COG1653	transport
GO596_RS01705	COG3345	alpha-galactosidase
GO596_RS01710	COG2207	Transcriptional regulator
GO596_RS01715	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GO596_RS01720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO596_RS01720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO596_RS01725	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO596_RS01730	COG2723	6-phospho-beta-galactosidase activity
GO596_RS01735	COG3711	transcriptional antiterminator
GO596_RS01760	COG0698	ribose 5-phosphate isomerase
GO596_RS01770	COG3842	ATPase activity
GO596_RS01795	COG1940	carbohydrate kinase activity
GO596_RS01800	COG2188	Transcriptional regulator
GO596_RS01810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GO596_RS01815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GO596_RS01825	COG1482	cell wall glycoprotein biosynthetic process
GO596_RS01830	COG2188	Transcriptional regulator
GO596_RS01835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO596_RS01840	COG2723	6-phospho-beta-galactosidase activity
GO596_RS01845	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO596_RS01850	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO596_RS01860	COG1363	Peptidase, m42
GO596_RS01875	COG2190	(PTS) system
GO596_RS01875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO596_RS01875	COG1263	PTS System
GO596_RS01885	COG1609	Transcriptional regulator
GO596_RS01890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GO596_RS01905	COG0456	acetyltransferase
GO596_RS01910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GO596_RS01945	COG0681	Belongs to the peptidase S26 family
GO596_RS01950	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO596_RS01955	COG2017	converts alpha-aldose to the beta-anomer
GO596_RS01960	COG0534	Mate efflux family protein
GO596_RS01965	COG3534	alpha-L-arabinofuranosidase
GO596_RS01980	COG3507	Belongs to the glycosyl hydrolase 43 family
GO596_RS01985	COG3507	Belongs to the glycosyl hydrolase 43 family
GO596_RS01990	COG3940	Belongs to the glycosyl hydrolase 43 family
GO596_RS02030	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GO596_RS02035	COG2160	L-arabinose isomerase activity
GO596_RS02050	COG1609	Transcriptional regulator
GO596_RS02060	COG4667	esterase of the alpha-beta hydrolase superfamily
GO596_RS02065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO596_RS02085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GO596_RS02100	COG1131	(ABC) transporter
GO596_RS02105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO596_RS02110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO596_RS02115	COG1028	Short-chain dehydrogenase reductase Sdr
GO596_RS02155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO596_RS02165	COG0564	pseudouridine synthase activity
GO596_RS02180	COG1396	sequence-specific DNA binding
GO596_RS02195	COG1116	anion transmembrane transporter activity
GO596_RS02195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO596_RS02200	COG4120	Belongs to the binding-protein-dependent transport system permease family
GO596_RS02210	COG3716	PTS system mannose fructose sorbose family IID component
GO596_RS02215	COG3715	PTS system
GO596_RS02235	COG2197	response regulator
GO596_RS02240	COG4585	Histidine kinase
GO596_RS02250	COG1621	beta-fructofuranosidase activity
GO596_RS02250	COG3583	domain protein
GO596_RS02250	COG5492	domain, Protein
GO596_RS02255	COG0561	phosphatase activity
GO596_RS02265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO596_RS02270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GO596_RS02280	COG1363	Peptidase, m42
GO596_RS02285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GO596_RS02310	COG0827	DNA restriction-modification system
GO596_RS02335	COG4537	Required for transformation and DNA binding
GO596_RS02340	COG1459	type II secretion system
GO596_RS02345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GO596_RS02375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO596_RS02380	COG1121	(ABC) transporter
GO596_RS02390	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GO596_RS02430	COG0535	radical SAM domain protein
GO596_RS02435	COG1396	sequence-specific DNA binding
GO596_RS02445	COG1280	lysine exporter protein (LysE YggA)
GO596_RS02455	COG1136	(ABC) transporter
GO596_RS02455	COG0577	efflux transmembrane transporter activity
GO596_RS02460	COG1770	oligopeptidase
GO596_RS02465	COG0515	serine threonine protein kinase
GO596_RS02470	COG1132	(ABC) transporter
GO596_RS02495	COG3620	sequence-specific DNA binding
GO596_RS02510	COG1674	ftsk spoiiie
GO596_RS02545	COG0433	COG0433 Predicted ATPase
GO596_RS02560	COG3942	CHAP domain
GO596_RS02655	COG0203	ribosomal protein L17
GO596_RS02660	COG0202	RNA polymerase activity
GO596_RS02665	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GO596_RS02690	COG0201	protein transport
GO596_RS02700	COG1841	ribosomal large subunit assembly
GO596_RS02705	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GO596_RS02725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GO596_RS02735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GO596_RS02750	COG0255	Belongs to the universal ribosomal protein uL29 family
GO596_RS02755	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GO596_RS02780	COG0089	rRNA binding
GO596_RS02785	COG0088	Forms part of the polypeptide exit tunnel
GO596_RS02795	COG0051	transcription antitermination factor activity, RNA binding
GO596_RS02800	COG0534	Mate efflux family protein
GO596_RS02815	COG2755	lipolytic protein G-D-S-L family
GO596_RS02815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GO596_RS02825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GO596_RS02830	COG2255	four-way junction helicase activity
GO596_RS02840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GO596_RS02850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GO596_RS02855	COG1683	Conserved Protein
GO596_RS02860	COG0151	Belongs to the GarS family
GO596_RS02865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GO596_RS02875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GO596_RS02880	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GO596_RS02895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GO596_RS02900	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO596_RS02905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO596_RS02910	COG0416	fatty acid biosynthetic process
GO596_RS02920	COG0436	Aminotransferase
GO596_RS02930	COG3942	CHAP domain
GO596_RS02940	COG1792	Involved in formation and maintenance of cell shape
GO596_RS03115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GO596_RS03145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GO596_RS03150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GO596_RS03160	COG0012	GTP binding
GO596_RS03170	COG1597	lipid kinase activity
GO596_RS03175	COG0592	DNA-directed DNA polymerase activity
GO596_RS03185	COG1475	DNA binding
GO596_RS03190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO596_RS03215	COG4485	Bacterial membrane protein, YfhO
GO596_RS03220	COG0488	(ABC) transporter
GO596_RS03235	COG0516	GMP reductase activity
GO596_RS03235	COG0517	IMP dehydrogenase activity
GO596_RS03245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GO596_RS03255	COG0612	Peptidase, M16
GO596_RS03260	COG0612	Peptidase, M16
GO596_RS03270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GO596_RS03275	COG1122	ATPase activity
GO596_RS03280	COG1122	ATPase activity
GO596_RS03300	COG0546	phosphoglycolate phosphatase activity
GO596_RS03305	COG1760	l-serine dehydratase
GO596_RS03310	COG1760	l-serine dehydratase
GO596_RS03320	COG0445	tRNA wobble uridine modification
GO596_RS03335	COG0305	Participates in initiation and elongation during chromosome replication
GO596_RS03340	COG4466	Protein conserved in bacteria
GO596_RS03350	COG1309	transcriptional regulator
GO596_RS03355	COG1511	domain protein
GO596_RS03355	COG1511	domain protein
GO596_RS03360	COG3759	membrane
GO596_RS03385	COG2188	Transcriptional regulator
GO596_RS03390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO596_RS03390	COG1263	PTS System
GO596_RS03395	COG0366	Alpha amylase catalytic
GO596_RS03405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GO596_RS03425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GO596_RS03430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GO596_RS03435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO596_RS03435	COG2190	(PTS) system
GO596_RS03435	COG1263	PTS System
GO596_RS03470	COG0519	Catalyzes the synthesis of GMP from XMP
GO596_RS03480	COG1058	Belongs to the CinA family
GO596_RS03480	COG1546	Belongs to the CinA family
GO596_RS03490	COG1393	Belongs to the ArsC family
GO596_RS03495	COG4472	Bacterial protein of unknown function (DUF965)
GO596_RS03515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GO596_RS03515	COG1328	CTP reductase activity
GO596_RS03525	COG0602	queuosine metabolic process
GO596_RS03530	COG1309	transcriptional regulator
GO596_RS03560	COG3590	peptidase
GO596_RS03565	COG1396	sequence-specific DNA binding
GO596_RS03580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GO596_RS03590	COG4463	regulation of RNA biosynthetic process
GO596_RS03595	COG0542	response to heat
GO596_RS03600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO596_RS03655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO596_RS03655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO596_RS03660	COG1832	CoA-binding protein
GO596_RS03675	COG0343	queuine tRNA-ribosyltransferase activity
GO596_RS03685	COG1268	BioY protein
GO596_RS03690	COG1234	tRNA 3'-trailer cleavage
GO596_RS03705	COG0166	Belongs to the GPI family
GO596_RS03710	COG2171	N-acyltransferase activity
GO596_RS03720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GO596_RS03730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GO596_RS03745	COG0756	dUTP diphosphatase activity
GO596_RS03760	COG4989	oxidoreductase activity
GO596_RS03765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO596_RS03770	COG2807	transmembrane transport
GO596_RS03785	COG0594	ribonuclease P activity
GO596_RS03800	COG1131	(ABC) transporter
GO596_RS03830	COG2273	Hydrolase Family 16
GO596_RS03855	COG0395	ABC-type sugar transport system, permease component
GO596_RS03865	COG2273	Hydrolase Family 16
GO596_RS03875	COG0745	RESPONSE REGULATOR receiver
GO596_RS03880	COG5002	protein histidine kinase activity
GO596_RS03895	COG1696	Membrane protein involved in D-alanine export
GO596_RS03900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO596_RS03905	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GO596_RS03910	COG0583	DNA-binding transcription factor activity
GO596_RS03915	COG0281	malic enzyme
GO596_RS03925	COG0084	hydrolase, TatD family'
GO596_RS04005	COG3290	protein histidine kinase activity
GO596_RS04030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GO596_RS04050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GO596_RS04060	COG0049	tRNA binding
GO596_RS04065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GO596_RS04070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO596_RS04075	COG0126	phosphoglycerate kinase activity
GO596_RS04085	COG0789	Transcriptional regulator
GO596_RS04090	COG0174	glutamine synthetase
GO596_RS04095	COG0067	glutamate synthase
GO596_RS04095	COG0069	glutamate synthase activity
GO596_RS04095	COG0070	glutamate synthase
GO596_RS04100	COG0493	'glutamate synthase
GO596_RS04105	COG3942	CHAP domain
GO596_RS04115	COG5503	Protein of unknown function (DUF1447)
GO596_RS04120	COG1214	PFAM Peptidase M22, glycoprotease
GO596_RS04125	COG0456	acetyltransferase
GO596_RS04135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GO596_RS04160	COG2081	HI0933 family
GO596_RS04180	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GO596_RS04200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GO596_RS04215	COG1882	Formate acetyltransferase
GO596_RS04230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GO596_RS04235	COG0681	Belongs to the peptidase S26 family
GO596_RS04240	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GO596_RS04260	COG1132	(ABC) transporter
GO596_RS04270	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GO596_RS04280	COG0157	Belongs to the NadC ModD family
GO596_RS04290	COG3118	belongs to the thioredoxin family
GO596_RS04295	COG1063	alcohol dehydrogenase
GO596_RS04330	COG0431	NADPH-dependent FMN reductase
GO596_RS04330	COG1053	succinate dehydrogenase
GO596_RS04330	COG3976	FMN-binding domain protein
GO596_RS04335	COG1194	a g-specific adenine glycosylase
GO596_RS04345	COG0681	Belongs to the peptidase S26 family
GO596_RS04380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GO596_RS04405	COG0006	proline dipeptidase activity
GO596_RS04415	COG2131	deaminase
GO596_RS04425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GO596_RS04435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GO596_RS04440	COG1609	Transcriptional regulator
GO596_RS04445	COG1621	beta-fructofuranosidase activity
GO596_RS04450	COG1263	PTS System
GO596_RS04450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO596_RS04450	COG2190	(PTS) system
GO596_RS04455	COG1940	carbohydrate kinase activity
GO596_RS04465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO596_RS04470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO596_RS04485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GO596_RS04505	COG3655	Transcriptional regulator
GO596_RS04510	COG0252	asparaginase activity
GO596_RS04515	COG0561	phosphatase activity
GO596_RS04520	COG0589	response to stress
GO596_RS04530	COG0436	Aminotransferase
GO596_RS04535	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GO596_RS04540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GO596_RS04545	COG0154	amidase activity
GO596_RS04560	COG0697	spore germination
GO596_RS04570	COG0477	Major facilitator Superfamily
GO596_RS04580	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GO596_RS04585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GO596_RS04590	COG1534	Rna-binding protein
GO596_RS04595	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GO596_RS04600	COG1713	HD superfamily hydrolase involved in NAD metabolism
GO596_RS04605	COG1335	isochorismatase
GO596_RS04610	COG0799	negative regulation of ribosome biogenesis
GO596_RS04615	COG2226	methyltransferase
GO596_RS04620	COG1002	Type II restriction enzyme, methylase subunits
GO596_RS04625	COG1061	Type III restriction enzyme res subunit
GO596_RS04630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GO596_RS04640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GO596_RS04650	COG0789	Transcriptional regulator
GO596_RS04655	COG0217	transcriptional regulatory protein
GO596_RS04660	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GO596_RS04665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO596_RS04670	COG1473	amidohydrolase
GO596_RS04675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO596_RS04695	COG1959	2 iron, 2 sulfur cluster binding
GO596_RS04700	COG2910	NAD(P)H-binding
GO596_RS04705	COG1114	Component of the transport system for branched-chain amino acids
GO596_RS04710	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GO596_RS04720	COG1122	ATPase activity
GO596_RS04730	COG0569	domain protein
GO596_RS04735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO596_RS04745	COG1704	LemA family
GO596_RS04750	COG0501	Belongs to the peptidase M48B family
GO596_RS04760	COG0745	RESPONSE REGULATOR receiver
GO596_RS04765	COG5002	protein histidine kinase activity
GO596_RS04780	COG1484	DNA-dependent DNA replication
GO596_RS04810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GO596_RS04825	COG1254	Belongs to the acylphosphatase family
GO596_RS04830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO596_RS04850	COG3763	UPF0154 protein
GO596_RS04855	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GO596_RS04875	COG0582	viral genome integration into host DNA
GO596_RS04890	COG1187	pseudouridine synthase activity
GO596_RS04895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GO596_RS04900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO596_RS04905	COG0569	domain protein
GO596_RS04910	COG0531	amino acid
GO596_RS04920	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GO596_RS04925	COG0671	phosphoesterase, PA-phosphatase related
GO596_RS04930	COG1242	4 iron, 4 sulfur cluster binding
GO596_RS04935	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GO596_RS04940	COG1119	ATPase activity
GO596_RS04945	COG2211	Major facilitator Superfamily
GO596_RS04945	COG2190	(PTS) system
GO596_RS04950	COG1253	flavin adenine dinucleotide binding
GO596_RS04955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GO596_RS04980	COG3022	response to hydroperoxide
GO596_RS04995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO596_RS05000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO596_RS05005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GO596_RS05010	COG1120	ATPase activity
GO596_RS05020	COG2244	polysaccharide biosynthetic process
GO596_RS05025	COG0626	cystathionine gamma-synthase activity
GO596_RS05030	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GO596_RS05040	COG0583	DNA-binding transcription factor activity
GO596_RS05060	COG4471	UPF0298 protein
GO596_RS05090	COG0517	IMP dehydrogenase activity
GO596_RS05090	COG0516	GMP reductase activity
GO596_RS05100	COG0470	DNA polymerase III
GO596_RS05105	COG1774	PSP1 C-terminal conserved region
GO596_RS05120	COG0004	ammonium transporteR
GO596_RS05125	COG0347	Belongs to the P(II) protein family
GO596_RS05140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO596_RS05145	COG1393	Belongs to the ArsC family
GO596_RS05150	COG0708	Exodeoxyribonuclease III
GO596_RS05155	COG0640	Transcriptional regulator
GO596_RS05185	COG1028	Short-chain dehydrogenase reductase Sdr
GO596_RS05200	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GO596_RS05225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GO596_RS05230	COG1674	ftsk spoiiie
GO596_RS05260	COG2996	Protein conserved in bacteria
GO596_RS05270	COG4479	Belongs to the UPF0346 family
GO596_RS05275	COG1702	phosphate starvation-inducible protein PhoH
GO596_RS05290	COG0366	Alpha amylase catalytic
GO596_RS05295	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GO596_RS05300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GO596_RS05310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GO596_RS05320	COG2814	Major facilitator Superfamily
GO596_RS05335	COG0557	exoribonuclease II activity
GO596_RS05345	COG1846	Transcriptional regulator
GO596_RS05360	COG0778	Nitroreductase
GO596_RS05370	COG1846	Transcriptional regulator
GO596_RS05375	COG1321	iron dependent repressor
GO596_RS05380	COG1811	Na channel or pump
GO596_RS05390	COG2816	NAD+ diphosphatase activity
GO596_RS05400	COG0006	proline dipeptidase activity
GO596_RS05405	COG1609	Transcriptional regulator
GO596_RS05415	COG0438	transferase activity, transferring glycosyl groups
GO596_RS05420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GO596_RS05430	COG4716	Myosin-crossreactive antigen
GO596_RS05445	COG0745	RESPONSE REGULATOR receiver
GO596_RS05450	COG5002	protein histidine kinase activity
GO596_RS05450	COG3850	Histidine kinase
GO596_RS05465	COG0765	amino acid transport
GO596_RS05470	COG0765	amino acid transport
GO596_RS05475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO596_RS05480	COG1126	abc transporter atp-binding protein
GO596_RS05485	COG0745	RESPONSE REGULATOR receiver
GO596_RS05490	COG5002	protein histidine kinase activity
GO596_RS05495	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GO596_RS05515	COG1674	ftsk spoiiie
GO596_RS05525	COG2946	Replication initiation factor
GO596_RS05555	COG0791	NLP P60 protein
GO596_RS05555	COG0741	lytic transglycosylase activity
GO596_RS05620	COG1196	nuclear chromosome segregation
GO596_RS05630	COG0561	phosphatase activity
GO596_RS05635	COG0561	phosphatase activity
GO596_RS05640	COG0552	protein localization to endoplasmic reticulum
GO596_RS05650	COG3689	TIGRFAM TIGR03943 family protein
GO596_RS05655	COG0701	Predicted permease
GO596_RS05665	COG2183	response to ionizing radiation
GO596_RS05670	COG3091	SprT-like family
GO596_RS05710	COG0826	peptidase U32
GO596_RS05720	COG4443	Transcriptional Coactivator p15 (PC4)
GO596_RS05735	COG1309	transcriptional regulator
GO596_RS05755	COG0406	alpha-ribazole phosphatase activity
GO596_RS05775	COG0386	Belongs to the glutathione peroxidase family
GO596_RS05780	COG1164	Oligoendopeptidase f
GO596_RS05790	COG0772	Belongs to the SEDS family
GO596_RS05805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GO596_RS05830	COG1078	dGTPase activity
GO596_RS05850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO596_RS05860	COG2884	Cell division ATP-binding protein ftsE
GO596_RS05865	COG2177	Part of the ABC transporter FtsEX involved in
GO596_RS05880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO596_RS05880	COG1199	ATP-dependent helicase activity
GO596_RS05890	COG0436	Aminotransferase
GO596_RS05900	COG0017	Asparaginyl-tRNA synthetase
GO596_RS05920	COG0251	oxidation-reduction process
GO596_RS05935	COG1309	transcriptional regulator
GO596_RS05945	COG1660	Displays ATPase and GTPase activities
GO596_RS05970	COG1388	LysM domain
GO596_RS05970	COG1705	Flagellar rod assembly protein muramidase FlgJ
GO596_RS05980	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GO596_RS05985	COG1454	alcohol dehydrogenase
GO596_RS05995	COG0716	FMN binding
GO596_RS06005	COG1605	Chorismate mutase
GO596_RS06005	COG0287	Prephenate dehydrogenase
GO596_RS06010	COG0038	chloride channel
GO596_RS06025	COG0772	Belongs to the SEDS family
GO596_RS06035	COG0187	DNA topoisomerase II activity
GO596_RS06050	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GO596_RS06060	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GO596_RS06065	COG0560	Phosphoserine phosphatase
GO596_RS06075	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GO596_RS06085	COG0107	imidazoleglycerol-phosphate synthase activity
GO596_RS06100	COG1874	Beta-galactosidase
GO596_RS06100	COG0366	Alpha amylase catalytic
GO596_RS06115	COG0148	phosphopyruvate hydratase activity
GO596_RS06135	COG3442	glutamine amidotransferase
GO596_RS06140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GO596_RS06145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GO596_RS06160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GO596_RS06170	COG0647	UMP catabolic process
GO596_RS06185	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GO596_RS06190	COG1518	maintenance of DNA repeat elements
GO596_RS06220	COG0481	GTPase activity
GO596_RS06225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GO596_RS06230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GO596_RS06235	COG0077	Prephenate dehydratase
GO596_RS06240	COG1316	TRANSCRIPTIONal
GO596_RS06245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO596_RS06260	COG2211	Major facilitator Superfamily
GO596_RS06280	COG1131	(ABC) transporter
GO596_RS06295	COG0456	acetyltransferase
GO596_RS06325	COG0659	secondary active sulfate transmembrane transporter activity
GO596_RS06330	COG4166	transmembrane transport
GO596_RS06335	COG4166	transmembrane transport
GO596_RS06340	COG1187	pseudouridine synthase activity
GO596_RS06360	COG0488	(ABC) transporter
GO596_RS06365	COG1592	Rubrerythrin
GO596_RS06370	COG1126	abc transporter atp-binding protein
GO596_RS06375	COG0765	amino acid transport
GO596_RS06400	COG1396	sequence-specific DNA binding
GO596_RS06410	COG2814	Major facilitator Superfamily
GO596_RS06435	COG3833	ABC-type maltose transport systems, permease component
GO596_RS06440	COG1175	transmembrane transport
GO596_RS06450	COG1609	Transcriptional regulator
GO596_RS06455	COG1640	4-alpha-glucanotransferase
GO596_RS06460	COG0058	SHG alpha-glucan phosphorylase activity
GO596_RS06470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO596_RS06475	COG0436	Aminotransferase
GO596_RS06500	COG1970	mechanosensitive ion channel activity
GO596_RS06505	COG0358	DNA primase activity
GO596_RS06510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GO596_RS06515	COG2151	metal-sulfur cluster biosynthetic enzyme
GO596_RS06525	COG0463	Glycosyl transferase, family 2
GO596_RS06555	COG1216	Glycosyl transferase, family 2
GO596_RS06575	COG1216	Glycosyl transferase, family 2
GO596_RS06580	COG1216	Glycosyl transferase, family 2
GO596_RS06585	COG1368	sulfuric ester hydrolase activity
GO596_RS06595	COG0438	transferase activity, transferring glycosyl groups
GO596_RS06600	COG0463	Glycosyl transferase, family 2
GO596_RS06605	COG3942	CHAP domain
GO596_RS06620	COG2195	Cleaves the N-terminal amino acid of tripeptides
GO596_RS06640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GO596_RS06645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GO596_RS06650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GO596_RS06655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GO596_RS06660	COG1368	sulfuric ester hydrolase activity
GO596_RS06665	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GO596_RS06675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GO596_RS06680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GO596_RS06690	COG0287	Prephenate dehydrogenase
GO596_RS06705	COG0285	dihydrofolate synthase activity
GO596_RS06715	COG1104	cysteine desulfurase activity
GO596_RS06720	COG0301	tRNA thio-modification
GO596_RS06745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GO596_RS06750	COG0583	DNA-binding transcription factor activity
GO596_RS06760	COG0564	pseudouridine synthase activity
GO596_RS06765	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GO596_RS06775	COG0540	Belongs to the ATCase OTCase family
GO596_RS06780	COG0505	Belongs to the CarA family
GO596_RS06795	COG1136	(ABC) transporter
GO596_RS06800	COG0577	efflux transmembrane transporter activity
GO596_RS06820	COG1837	Belongs to the UPF0109 family
GO596_RS06835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GO596_RS06845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GO596_RS06850	COG0492	ferredoxin-NADP+ reductase activity
GO596_RS06855	COG1349	DNA-binding transcription factor activity
GO596_RS06860	COG1105	Belongs to the carbohydrate kinase PfkB family
GO596_RS06865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO596_RS06865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO596_RS06865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO596_RS06870	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GO596_RS06875	COG0646	methionine synthase
GO596_RS06875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GO596_RS06880	COG0667	Aldo Keto reductase
GO596_RS06895	COG0667	Aldo Keto reductase
GO596_RS06900	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO596_RS06910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GO596_RS06915	COG1705	Flagellar rod assembly protein muramidase FlgJ
GO596_RS06915	COG1388	LysM domain
GO596_RS06935	COG0617	tRNA 3'-terminal CCA addition
GO596_RS06940	COG0488	(ABC) transporter
GO596_RS06950	COG1132	(ABC) transporter
GO596_RS06955	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GO596_RS06960	COG0720	synthase
GO596_RS06965	COG0602	queuosine metabolic process
GO596_RS06980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GO596_RS06985	COG0456	acetyltransferase
GO596_RS06985	COG1214	PFAM Peptidase M22, glycoprotease
GO596_RS06990	COG0242	peptide deformylase activity
GO596_RS07005	COG1132	(ABC) transporter
GO596_RS07020	COG1917	Cupin 2, conserved barrel domain protein
GO596_RS07020	COG2207	Transcriptional regulator
GO596_RS07025	COG1263	PTS System
GO596_RS07025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO596_RS07025	COG2190	(PTS) system
GO596_RS07030	COG3394	polysaccharide catabolic process
GO596_RS07085	COG3279	Response regulator of the LytR AlgR family
GO596_RS07100	COG3290	protein histidine kinase activity
GO596_RS07135	COG1733	regulation of RNA biosynthetic process
GO596_RS07155	COG0517	IMP dehydrogenase activity
GO596_RS07155	COG1125	glycine betaine transport
GO596_RS07165	COG2357	RelA SpoT domain protein
GO596_RS07170	COG0745	RESPONSE REGULATOR receiver
GO596_RS07180	COG0656	L-ascorbic acid biosynthetic process
GO596_RS07185	COG0583	DNA-binding transcription factor activity
GO596_RS07195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO596_RS07200	COG0765	amino acid transport
GO596_RS07205	COG0765	amino acid transport
GO596_RS07210	COG1126	abc transporter atp-binding protein
GO596_RS07215	COG0765	amino acid transport
GO596_RS07220	COG0765	amino acid transport
GO596_RS07225	COG1126	abc transporter atp-binding protein
GO596_RS07230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO596_RS07255	COG1272	protein, Hemolysin III
GO596_RS07270	COG3425	synthase
GO596_RS07280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GO596_RS07290	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GO596_RS07300	COG0833	amino acid
GO596_RS07305	COG2040	homocysteine
GO596_RS07320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GO596_RS07350	COG2962	Rard protein
GO596_RS07355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO596_RS07360	COG0285	dihydrofolate synthase activity
GO596_RS07385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GO596_RS07395	COG1176	ABC-type spermidine putrescine transport system, permease component I
GO596_RS07400	COG1177	transmembrane transport
GO596_RS07420	COG1263	PTS System
GO596_RS07420	COG2190	(PTS) system
GO596_RS07420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO596_RS07425	COG2207	Transcriptional regulator
GO596_RS07440	COG2723	6-phospho-beta-galactosidase activity
GO596_RS07465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO596_RS07470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO596_RS07470	COG3711	transcriptional antiterminator
GO596_RS07475	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO596_RS07485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO596_RS07490	COG0561	phosphatase activity
GO596_RS07495	COG0561	phosphatase activity
GO596_RS07505	COG2723	6-phospho-beta-galactosidase activity
GO596_RS07515	COG0561	phosphatase activity
GO596_RS07520	COG1115	amino acid carrier protein
GO596_RS07525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO596_RS07535	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GO596_RS07560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GO596_RS07570	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GO596_RS07580	COG2873	o-acetylhomoserine
GO596_RS07585	COG0577	efflux transmembrane transporter activity
GO596_RS07585	COG1136	(ABC) transporter
GO596_RS07605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GO596_RS07610	COG0196	riboflavin kinase activity
GO596_RS07615	COG1393	Belongs to the ArsC family
GO596_RS07620	COG4476	Belongs to the UPF0223 family
GO596_RS07625	COG0483	inositol monophosphate 1-phosphatase activity
GO596_RS07645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO596_RS07650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GO596_RS07650	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GO596_RS07660	COG0573	inorganic phosphate transmembrane transporter activity
GO596_RS07665	COG0581	inorganic phosphate transmembrane transporter activity
GO596_RS07670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GO596_RS07675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GO596_RS07680	COG0704	Plays a role in the regulation of phosphate uptake
GO596_RS07690	COG0745	RESPONSE REGULATOR receiver
GO596_RS07695	COG5002	protein histidine kinase activity
GO596_RS07705	COG1072	(Pantothenic acid kinase))
GO596_RS07710	COG2813	Specifically methylates the guanine in position
GO596_RS07720	COG1744	ABC transporter substrate-binding protein PnrA-like
GO596_RS07725	COG3845	ABC transporter
GO596_RS07730	COG4603	Belongs to the binding-protein-dependent transport system permease family
GO596_RS07735	COG1079	Belongs to the binding-protein-dependent transport system permease family
GO596_RS07755	COG3764	Sortase (surface protein transpeptidase)
GO596_RS07760	COG0346	lactoylglutathione lyase activity
GO596_RS07775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GO596_RS07780	COG4684	Psort location CytoplasmicMembrane, score
GO596_RS07785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GO596_RS07800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GO596_RS07805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GO596_RS07810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO596_RS07815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO596_RS07830	COG0488	(ABC) transporter
GO596_RS07845	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GO596_RS07850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GO596_RS07855	COG0110	maltose O-acetyltransferase activity
GO596_RS07860	COG0758	DNA mediated transformation
GO596_RS07865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GO596_RS07890	COG1136	(ABC) transporter
GO596_RS07895	COG0577	efflux transmembrane transporter activity
GO596_RS07900	COG0745	RESPONSE REGULATOR receiver
GO596_RS07905	COG2205	protein histidine kinase activity
GO596_RS07910	COG4974	Belongs to the 'phage' integrase family
GO596_RS07915	COG1129	ABC transporter
GO596_RS07935	COG2375	cellular response to nickel ion
GO596_RS07935	COG1132	(ABC) transporter
GO596_RS07945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GO596_RS07955	COG2188	Transcriptional regulator
GO596_RS07985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GO596_RS08000	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GO596_RS08005	COG1461	Dihydroxyacetone kinase
GO596_RS08015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GO596_RS08045	COG1401	restriction endodeoxyribonuclease activity
GO596_RS08050	COG0542	response to heat
GO596_RS08060	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GO596_RS08080	COG5263	repeat protein
GO596_RS08080	COG0366	Alpha amylase catalytic
GO596_RS08085	COG1396	sequence-specific DNA binding
GO596_RS08160	COG0519	Catalyzes the synthesis of GMP from XMP
GO596_RS08160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GO596_RS08175	COG1132	(ABC) transporter
GO596_RS08200	COG0009	L-threonylcarbamoyladenylate synthase
GO596_RS08205	COG2890	protein-(glutamine-N5) methyltransferase activity
GO596_RS08210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GO596_RS08235	COG2233	PERMEase
GO596_RS08245	COG0516	GMP reductase activity
GO596_RS08250	COG0577	efflux transmembrane transporter activity
GO596_RS08255	COG1136	(ABC) transporter
GO596_RS08260	COG2723	6-phospho-beta-galactosidase activity
GO596_RS08270	COG4221	oxidoreductase activity
GO596_RS08275	COG0280	phosphate acetyltransferase
GO596_RS08280	COG0564	pseudouridine synthase activity
GO596_RS08290	COG2357	RelA SpoT domain protein
GO596_RS08295	COG4116	CYTH
GO596_RS08305	COG1104	cysteine desulfurase activity
GO596_RS08325	COG0628	permease
GO596_RS08340	COG2723	6-phospho-beta-galactosidase activity
GO596_RS08345	COG1115	amino acid carrier protein
GO596_RS08350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GO596_RS08360	COG1126	abc transporter atp-binding protein
GO596_RS08365	COG0765	amino acid transport
GO596_RS08370	COG2824	Alkylphosphonate utilization operon protein PhnA
GO596_RS08385	COG0469	pyruvate kinase activity
GO596_RS08390	COG0205	6-phosphofructokinase activity
GO596_RS08400	COG1725	Transcriptional regulator
GO596_RS08405	COG1131	(ABC) transporter
GO596_RS08420	COG0398	Pfam SNARE associated Golgi protein
GO596_RS08425	COG1380	Effector of murein hydrolase LrgA
GO596_RS08430	COG1346	cytolysis
GO596_RS08440	COG0539	negative regulation of cytoplasmic translation
GO596_RS08460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GO596_RS08465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GO596_RS08470	COG0187	DNA topoisomerase II activity
GO596_RS08495	COG1881	PFAM PEBP family protein
GO596_RS08505	COG0284	orotidine-5'-phosphate decarboxylase activity
GO596_RS08510	COG0167	dihydroorotate dehydrogenase activity
GO596_RS08525	COG1091	dTDP-4-dehydrorhamnose reductase activity
GO596_RS08555	COG0438	transferase activity, transferring glycosyl groups
GO596_RS08575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GO596_RS08580	COG0489	protein tyrosine kinase activity
GO596_RS08595	COG1316	TRANSCRIPTIONal
GO596_RS08605	COG0813	purine-nucleoside phosphorylase activity
GO596_RS08615	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GO596_RS08630	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GO596_RS08635	COG1573	uracil-dna glycosylase
GO596_RS08655	COG0322	excinuclease ABC activity
GO596_RS08660	COG2855	membrane
GO596_RS08665	COG0583	DNA-binding transcription factor activity
GO596_RS08675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GO596_RS08680	COG1136	(ABC) transporter
GO596_RS08710	COG0656	L-ascorbic acid biosynthetic process
GO596_RS08715	COG0789	Transcriptional regulator
GO596_RS08725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GO596_RS08740	COG1418	mRNA catabolic process
GO596_RS08750	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO596_RS08760	COG1937	Protein conserved in bacteria
GO596_RS08775	COG2814	Major facilitator Superfamily
GO596_RS08800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GO596_RS08810	COG0583	DNA-binding transcription factor activity
GO596_RS08815	COG0095	Lipoate-protein ligase
GO596_RS08820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO596_RS08825	COG0697	spore germination
GO596_RS08840	COG0022	dehydrogenase e1 component
GO596_RS08840	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO596_RS08845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO596_RS08855	COG1132	(ABC) transporter
GO596_RS08860	COG1132	(ABC) transporter
GO596_RS08870	COG0488	(ABC) transporter
GO596_RS08885	COG3842	ATPase activity
GO596_RS08900	COG4187	Peptidase family M20/M25/M40
GO596_RS08905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GO596_RS08910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GO596_RS08920	COG0765	amino acid transport
GO596_RS08925	COG1126	abc transporter atp-binding protein
GO596_RS08930	COG0583	DNA-binding transcription factor activity
GO596_RS08935	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GO596_RS08940	COG0531	amino acid
GO596_RS08945	COG3527	Alpha-acetolactate decarboxylase
GO596_RS08950	COG0028	Belongs to the TPP enzyme family
GO596_RS08960	COG0457	Tetratricopeptide repeat
GO596_RS08965	COG0628	permease
GO596_RS08970	COG1051	belongs to the nudix hydrolase family
GO596_RS08980	COG1088	dTDP-glucose 4,6-dehydratase activity
GO596_RS08990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GO596_RS09000	COG2384	SAM-dependent methyltransferase
GO596_RS09005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GO596_RS09015	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GO596_RS09025	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GO596_RS09030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GO596_RS09030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GO596_RS09035	COG0300	oxidoreductase activity
GO596_RS09050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GO596_RS09080	COG1074	ATP-dependent DNA helicase activity
GO596_RS09085	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GO596_RS09100	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GO596_RS09115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GO596_RS09165	COG1597	lipid kinase activity
GO596_RS09170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GO596_RS09175	COG4708	membrane
GO596_RS09180	COG2246	polysaccharide biosynthetic process
GO596_RS09190	COG0024	Methionine aminopeptidase
GO596_RS09195	COG4109	DRTGG domain
GO596_RS09200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO596_RS09205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GO596_RS09210	COG2207	Transcriptional regulator
GO596_RS09210	COG3708	Transcriptional regulator
GO596_RS09215	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GO596_RS09230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GO596_RS09235	COG1956	GAF domain-containing protein
GO596_RS09240	COG0066	3-isopropylmalate dehydratase activity
GO596_RS09280	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GO596_RS09310	COG0372	Belongs to the citrate synthase family
GO596_RS09315	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GO596_RS09320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GO596_RS09325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GO596_RS09335	COG3859	Proton-coupled thiamine transporter YuaJ
GO596_RS09345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GO596_RS09345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GO596_RS09355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO596_RS09355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO596_RS09365	COG1476	TRANSCRIPTIONal
GO596_RS09370	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO596_RS09375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GO596_RS09380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GO596_RS09385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GO596_RS09405	COG0436	Aminotransferase
GO596_RS09410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source