locus-tag	class	description
GPA00_RS00005	COG0719	Fe-S assembly protein
GPA00_RS00010	COG0716	FMN binding
GPA00_RS00020	COG1454	alcohol dehydrogenase
GPA00_RS00025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GPA00_RS00035	COG1388	LysM domain
GPA00_RS00035	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPA00_RS00060	COG1660	Displays ATPase and GTPase activities
GPA00_RS00070	COG1309	transcriptional regulator
GPA00_RS00085	COG0251	oxidation-reduction process
GPA00_RS00105	COG0017	Asparaginyl-tRNA synthetase
GPA00_RS00115	COG0436	Aminotransferase
GPA00_RS00125	COG1199	ATP-dependent helicase activity
GPA00_RS00125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPA00_RS00140	COG2177	Part of the ABC transporter FtsEX involved in
GPA00_RS00145	COG2884	Cell division ATP-binding protein ftsE
GPA00_RS00155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPA00_RS00175	COG1078	dGTPase activity
GPA00_RS00200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPA00_RS00215	COG0772	Belongs to the SEDS family
GPA00_RS00225	COG1164	Oligoendopeptidase f
GPA00_RS00230	COG0386	Belongs to the glutathione peroxidase family
GPA00_RS00250	COG0588	phosphoglycerate mutase activity
GPA00_RS00295	COG1309	transcriptional regulator
GPA00_RS00310	COG4443	Transcriptional Coactivator p15 (PC4)
GPA00_RS00320	COG0826	peptidase U32
GPA00_RS00360	COG3091	SprT-like family
GPA00_RS00365	COG2183	response to ionizing radiation
GPA00_RS00375	COG0701	Predicted permease
GPA00_RS00380	COG3689	TIGRFAM TIGR03943 family protein
GPA00_RS00390	COG0552	protein localization to endoplasmic reticulum
GPA00_RS00395	COG0561	phosphatase activity
GPA00_RS00400	COG0561	phosphatase activity
GPA00_RS00415	COG1196	nuclear chromosome segregation
GPA00_RS00480	COG0741	lytic transglycosylase activity
GPA00_RS00480	COG0791	NLP P60 protein
GPA00_RS00510	COG2946	Replication initiation factor
GPA00_RS00520	COG1674	ftsk spoiiie
GPA00_RS00540	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GPA00_RS00545	COG5002	protein histidine kinase activity
GPA00_RS00550	COG0745	RESPONSE REGULATOR receiver
GPA00_RS00555	COG1126	abc transporter atp-binding protein
GPA00_RS00560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA00_RS00565	COG0765	amino acid transport
GPA00_RS00570	COG0765	amino acid transport
GPA00_RS00585	COG5002	protein histidine kinase activity
GPA00_RS00585	COG3850	Histidine kinase
GPA00_RS00590	COG0745	RESPONSE REGULATOR receiver
GPA00_RS00605	COG4716	Myosin-crossreactive antigen
GPA00_RS00615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPA00_RS00620	COG0438	transferase activity, transferring glycosyl groups
GPA00_RS00630	COG1609	Transcriptional regulator
GPA00_RS00635	COG0006	proline dipeptidase activity
GPA00_RS00645	COG2816	NAD+ diphosphatase activity
GPA00_RS00655	COG1811	Na channel or pump
GPA00_RS00660	COG1321	iron dependent repressor
GPA00_RS00665	COG1846	Transcriptional regulator
GPA00_RS00675	COG0778	Nitroreductase
GPA00_RS00690	COG1846	Transcriptional regulator
GPA00_RS00700	COG0557	exoribonuclease II activity
GPA00_RS00715	COG2814	Major facilitator Superfamily
GPA00_RS00725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPA00_RS00735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPA00_RS00740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPA00_RS00745	COG0366	Alpha amylase catalytic
GPA00_RS00760	COG1702	phosphate starvation-inducible protein PhoH
GPA00_RS00765	COG4479	Belongs to the UPF0346 family
GPA00_RS00775	COG2996	Protein conserved in bacteria
GPA00_RS00805	COG1674	ftsk spoiiie
GPA00_RS00810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPA00_RS00835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPA00_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
GPA00_RS00865	COG1695	Transcriptional regulator
GPA00_RS00890	COG0640	Transcriptional regulator
GPA00_RS00895	COG0708	Exodeoxyribonuclease III
GPA00_RS00900	COG1393	Belongs to the ArsC family
GPA00_RS00905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPA00_RS00920	COG0347	Belongs to the P(II) protein family
GPA00_RS00925	COG0004	ammonium transporteR
GPA00_RS00940	COG1774	PSP1 C-terminal conserved region
GPA00_RS00945	COG0470	DNA polymerase III
GPA00_RS00955	COG0516	GMP reductase activity
GPA00_RS00955	COG0517	IMP dehydrogenase activity
GPA00_RS00985	COG4471	UPF0298 protein
GPA00_RS01005	COG0583	DNA-binding transcription factor activity
GPA00_RS01015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GPA00_RS01020	COG0626	cystathionine gamma-synthase activity
GPA00_RS01025	COG2244	polysaccharide biosynthetic process
GPA00_RS01035	COG1120	ATPase activity
GPA00_RS01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPA00_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA00_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPA00_RS01065	COG3022	response to hydroperoxide
GPA00_RS01090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPA00_RS01095	COG1253	flavin adenine dinucleotide binding
GPA00_RS01100	COG2190	(PTS) system
GPA00_RS01100	COG2211	Major facilitator Superfamily
GPA00_RS01105	COG1119	ATPase activity
GPA00_RS01110	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GPA00_RS01115	COG1242	4 iron, 4 sulfur cluster binding
GPA00_RS01120	COG0671	phosphoesterase, PA-phosphatase related
GPA00_RS01125	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPA00_RS01135	COG0531	amino acid
GPA00_RS01140	COG0569	domain protein
GPA00_RS01145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPA00_RS01150	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPA00_RS01155	COG1187	pseudouridine synthase activity
GPA00_RS01170	COG0582	viral genome integration into host DNA
GPA00_RS01190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPA00_RS01195	COG3763	UPF0154 protein
GPA00_RS01215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPA00_RS01220	COG1254	Belongs to the acylphosphatase family
GPA00_RS01235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPA00_RS01265	COG1484	DNA-dependent DNA replication
GPA00_RS01280	COG5002	protein histidine kinase activity
GPA00_RS01285	COG0745	RESPONSE REGULATOR receiver
GPA00_RS01295	COG0501	Belongs to the peptidase M48B family
GPA00_RS01300	COG1704	LemA family
GPA00_RS01310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPA00_RS01315	COG0569	domain protein
GPA00_RS01325	COG1122	ATPase activity
GPA00_RS01335	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPA00_RS01340	COG1114	Component of the transport system for branched-chain amino acids
GPA00_RS01345	COG2910	NAD(P)H-binding
GPA00_RS01350	COG1959	2 iron, 2 sulfur cluster binding
GPA00_RS01370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA00_RS01375	COG1473	amidohydrolase
GPA00_RS01380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA00_RS01385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GPA00_RS01390	COG0217	transcriptional regulatory protein
GPA00_RS01395	COG0789	Transcriptional regulator
GPA00_RS01415	COG2226	methyltransferase
GPA00_RS01420	COG0799	negative regulation of ribosome biogenesis
GPA00_RS01425	COG1713	HD superfamily hydrolase involved in NAD metabolism
GPA00_RS01430	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPA00_RS01435	COG1534	Rna-binding protein
GPA00_RS01440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPA00_RS01445	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GPA00_RS01455	COG0477	Major facilitator Superfamily
GPA00_RS01465	COG0697	spore germination
GPA00_RS01480	COG0154	amidase activity
GPA00_RS01485	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPA00_RS01490	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GPA00_RS01495	COG0436	Aminotransferase
GPA00_RS01505	COG0589	response to stress
GPA00_RS01510	COG0561	phosphatase activity
GPA00_RS01515	COG0252	asparaginase activity
GPA00_RS01525	COG3655	Transcriptional regulator
GPA00_RS01545	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPA00_RS01560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPA00_RS01565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPA00_RS01575	COG1940	carbohydrate kinase activity
GPA00_RS01580	COG2190	(PTS) system
GPA00_RS01580	COG1263	PTS System
GPA00_RS01580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA00_RS01585	COG1621	beta-fructofuranosidase activity
GPA00_RS01590	COG1609	Transcriptional regulator
GPA00_RS01595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPA00_RS01605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPA00_RS01620	COG2131	deaminase
GPA00_RS01625	COG0006	proline dipeptidase activity
GPA00_RS01650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPA00_RS01685	COG0681	Belongs to the peptidase S26 family
GPA00_RS01695	COG1194	a g-specific adenine glycosylase
GPA00_RS01700	COG3976	FMN-binding domain protein
GPA00_RS01700	COG0431	NADPH-dependent FMN reductase
GPA00_RS01700	COG1053	succinate dehydrogenase
GPA00_RS01750	COG1063	alcohol dehydrogenase
GPA00_RS01755	COG3118	belongs to the thioredoxin family
GPA00_RS01765	COG0157	Belongs to the NadC ModD family
GPA00_RS01775	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPA00_RS01800	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPA00_RS01805	COG0681	Belongs to the peptidase S26 family
GPA00_RS01810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPA00_RS01825	COG1882	Formate acetyltransferase
GPA00_RS01840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GPA00_RS01880	COG2081	HI0933 family
GPA00_RS01905	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GPA00_RS01915	COG0456	acetyltransferase
GPA00_RS01920	COG1214	PFAM Peptidase M22, glycoprotease
GPA00_RS01925	COG5503	Protein of unknown function (DUF1447)
GPA00_RS01935	COG3942	CHAP domain
GPA00_RS01940	COG0493	'glutamate synthase
GPA00_RS01945	COG0067	glutamate synthase
GPA00_RS01945	COG0069	glutamate synthase activity
GPA00_RS01945	COG0070	glutamate synthase
GPA00_RS01950	COG0174	glutamine synthetase
GPA00_RS01955	COG0789	Transcriptional regulator
GPA00_RS01965	COG0126	phosphoglycerate kinase activity
GPA00_RS01970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPA00_RS01975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPA00_RS01980	COG0049	tRNA binding
GPA00_RS01990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPA00_RS02005	COG1564	THIamine pyrophosphokinase
GPA00_RS02010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPA00_RS02030	COG3290	protein histidine kinase activity
GPA00_RS02070	COG0463	Glycosyl transferase, family 2
GPA00_RS02105	COG2274	protein secretion by the type I secretion system
GPA00_RS02110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPA00_RS02130	COG0084	hydrolase, TatD family'
GPA00_RS02140	COG0281	malic enzyme
GPA00_RS02145	COG0583	DNA-binding transcription factor activity
GPA00_RS02150	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GPA00_RS02155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPA00_RS02160	COG1696	Membrane protein involved in D-alanine export
GPA00_RS02175	COG5002	protein histidine kinase activity
GPA00_RS02180	COG0745	RESPONSE REGULATOR receiver
GPA00_RS02185	COG2207	Transcriptional regulator
GPA00_RS02190	COG2273	Hydrolase Family 16
GPA00_RS02200	COG0395	ABC-type sugar transport system, permease component
GPA00_RS02225	COG2273	Hydrolase Family 16
GPA00_RS02255	COG1131	(ABC) transporter
GPA00_RS02270	COG0594	ribonuclease P activity
GPA00_RS02280	COG0137	argininosuccinate synthase activity
GPA00_RS02285	COG2807	transmembrane transport
GPA00_RS02290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPA00_RS02295	COG4989	oxidoreductase activity
GPA00_RS02315	COG0756	dUTP diphosphatase activity
GPA00_RS02330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GPA00_RS02340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPA00_RS02350	COG2171	N-acyltransferase activity
GPA00_RS02355	COG0166	Belongs to the GPI family
GPA00_RS02370	COG1234	tRNA 3'-trailer cleavage
GPA00_RS02375	COG1268	BioY protein
GPA00_RS02385	COG0343	queuine tRNA-ribosyltransferase activity
GPA00_RS02400	COG1832	CoA-binding protein
GPA00_RS02405	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPA00_RS02405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPA00_RS02430	COG0464	growth
GPA00_RS02465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPA00_RS02470	COG0542	response to heat
GPA00_RS02475	COG4463	regulation of RNA biosynthetic process
GPA00_RS02485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPA00_RS02505	COG1396	sequence-specific DNA binding
GPA00_RS02510	COG3590	peptidase
GPA00_RS02540	COG1309	transcriptional regulator
GPA00_RS02555	COG1328	CTP reductase activity
GPA00_RS02555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPA00_RS02575	COG4472	Bacterial protein of unknown function (DUF965)
GPA00_RS02580	COG1393	Belongs to the ArsC family
GPA00_RS02590	COG1058	Belongs to the CinA family
GPA00_RS02590	COG1546	Belongs to the CinA family
GPA00_RS02600	COG0519	Catalyzes the synthesis of GMP from XMP
GPA00_RS02635	COG1263	PTS System
GPA00_RS02635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA00_RS02635	COG2190	(PTS) system
GPA00_RS02640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPA00_RS02645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPA00_RS02665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPA00_RS02675	COG0366	Alpha amylase catalytic
GPA00_RS02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA00_RS02680	COG1263	PTS System
GPA00_RS02685	COG2188	Transcriptional regulator
GPA00_RS02735	COG1674	ftsk spoiiie
GPA00_RS02740	COG4499	WXG100 protein secretion system (Wss), protein YukC
GPA00_RS02755	COG4842	Belongs to the WXG100 family
GPA00_RS02775	COG3759	membrane
GPA00_RS02780	COG1511	domain protein
GPA00_RS02780	COG1511	domain protein
GPA00_RS02785	COG1309	transcriptional regulator
GPA00_RS02795	COG4466	Protein conserved in bacteria
GPA00_RS02800	COG0305	Participates in initiation and elongation during chromosome replication
GPA00_RS02815	COG0445	tRNA wobble uridine modification
GPA00_RS02825	COG1760	l-serine dehydratase
GPA00_RS02830	COG1760	l-serine dehydratase
GPA00_RS02835	COG0546	phosphoglycolate phosphatase activity
GPA00_RS02855	COG1122	ATPase activity
GPA00_RS02860	COG1122	ATPase activity
GPA00_RS02865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPA00_RS02875	COG0612	Peptidase, M16
GPA00_RS02880	COG0612	Peptidase, M16
GPA00_RS02890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPA00_RS02900	COG0517	IMP dehydrogenase activity
GPA00_RS02900	COG0516	GMP reductase activity
GPA00_RS02915	COG0488	(ABC) transporter
GPA00_RS02920	COG4485	Bacterial membrane protein, YfhO
GPA00_RS02945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPA00_RS02950	COG1475	DNA binding
GPA00_RS02960	COG0592	DNA-directed DNA polymerase activity
GPA00_RS02965	COG1597	lipid kinase activity
GPA00_RS02975	COG0012	GTP binding
GPA00_RS02985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPA00_RS02990	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPA00_RS03020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPA00_RS03195	COG1792	Involved in formation and maintenance of cell shape
GPA00_RS03205	COG3942	CHAP domain
GPA00_RS03215	COG0436	Aminotransferase
GPA00_RS03225	COG0416	fatty acid biosynthetic process
GPA00_RS03230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPA00_RS03235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPA00_RS03240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPA00_RS03250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPA00_RS03255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPA00_RS03265	COG0151	Belongs to the GarS family
GPA00_RS03270	COG1683	Conserved Protein
GPA00_RS03275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPA00_RS03290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPA00_RS03300	COG2255	four-way junction helicase activity
GPA00_RS03305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPA00_RS03315	COG2755	lipolytic protein G-D-S-L family
GPA00_RS03315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GPA00_RS03330	COG0534	Mate efflux family protein
GPA00_RS03335	COG0051	transcription antitermination factor activity, RNA binding
GPA00_RS03345	COG0088	Forms part of the polypeptide exit tunnel
GPA00_RS03350	COG0089	rRNA binding
GPA00_RS03375	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPA00_RS03380	COG0255	Belongs to the universal ribosomal protein uL29 family
GPA00_RS03395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPA00_RS03405	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPA00_RS03425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPA00_RS03430	COG1841	ribosomal large subunit assembly
GPA00_RS03440	COG0201	protein transport
GPA00_RS03465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPA00_RS03470	COG0202	RNA polymerase activity
GPA00_RS03475	COG0203	ribosomal protein L17
GPA00_RS03585	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPA00_RS03595	COG1121	(ABC) transporter
GPA00_RS03600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPA00_RS03620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPA00_RS03630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPA00_RS03635	COG1459	type II secretion system
GPA00_RS03640	COG4537	Required for transformation and DNA binding
GPA00_RS03665	COG0827	DNA restriction-modification system
GPA00_RS03690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPA00_RS03695	COG1363	Peptidase, m42
GPA00_RS03705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPA00_RS03710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPA00_RS03725	COG0561	phosphatase activity
GPA00_RS03730	COG1621	beta-fructofuranosidase activity
GPA00_RS03730	COG3583	domain protein
GPA00_RS03730	COG5492	domain, Protein
GPA00_RS03740	COG4585	Histidine kinase
GPA00_RS03745	COG2197	response regulator
GPA00_RS03765	COG3715	PTS system
GPA00_RS03770	COG3716	PTS system mannose fructose sorbose family IID component
GPA00_RS03780	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPA00_RS03785	COG1116	anion transmembrane transporter activity
GPA00_RS03785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPA00_RS03800	COG1396	sequence-specific DNA binding
GPA00_RS03820	COG0564	pseudouridine synthase activity
GPA00_RS03830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPA00_RS03850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPA00_RS03855	COG4667	esterase of the alpha-beta hydrolase superfamily
GPA00_RS03865	COG1609	Transcriptional regulator
GPA00_RS03880	COG2160	L-arabinose isomerase activity
GPA00_RS03885	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GPA00_RS03925	COG3940	Belongs to the glycosyl hydrolase 43 family
GPA00_RS03930	COG3507	Belongs to the glycosyl hydrolase 43 family
GPA00_RS03935	COG3507	Belongs to the glycosyl hydrolase 43 family
GPA00_RS03950	COG3534	alpha-L-arabinofuranosidase
GPA00_RS03955	COG0534	Mate efflux family protein
GPA00_RS03960	COG2017	converts alpha-aldose to the beta-anomer
GPA00_RS03965	COG0657	acetylesterase activity
GPA00_RS03970	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPA00_RS03975	COG0681	Belongs to the peptidase S26 family
GPA00_RS04010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPA00_RS04015	COG0456	acetyltransferase
GPA00_RS04030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPA00_RS04035	COG1609	Transcriptional regulator
GPA00_RS04045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA00_RS04045	COG2190	(PTS) system
GPA00_RS04045	COG1263	PTS System
GPA00_RS04060	COG1363	Peptidase, m42
GPA00_RS04070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA00_RS04075	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPA00_RS04080	COG2723	6-phospho-beta-galactosidase activity
GPA00_RS04085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA00_RS04090	COG2188	Transcriptional regulator
GPA00_RS04095	COG1482	cell wall glycoprotein biosynthetic process
GPA00_RS04105	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPA00_RS04110	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPA00_RS04120	COG2188	Transcriptional regulator
GPA00_RS04125	COG1940	carbohydrate kinase activity
GPA00_RS04150	COG3842	ATPase activity
GPA00_RS04160	COG0698	ribose 5-phosphate isomerase
GPA00_RS04185	COG3711	transcriptional antiterminator
GPA00_RS04190	COG2723	6-phospho-beta-galactosidase activity
GPA00_RS04195	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPA00_RS04200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA00_RS04200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA00_RS04205	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GPA00_RS04210	COG2207	Transcriptional regulator
GPA00_RS04215	COG3345	alpha-galactosidase
GPA00_RS04220	COG1653	transport
GPA00_RS04225	COG1175	transmembrane transport
GPA00_RS04230	COG0395	ABC-type sugar transport system, permease component
GPA00_RS04235	COG0366	Alpha amylase catalytic
GPA00_RS04240	COG0366	Alpha amylase catalytic
GPA00_RS04275	COG1609	Transcriptional regulator
GPA00_RS04280	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPA00_RS04285	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GPA00_RS04290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPA00_RS04300	COG1862	Preprotein translocase
GPA00_RS04305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPA00_RS04310	COG4589	Belongs to the CDS family
GPA00_RS04335	COG1846	Transcriptional regulator
GPA00_RS04340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPA00_RS04365	COG1454	alcohol dehydrogenase
GPA00_RS04365	COG1012	belongs to the aldehyde dehydrogenase family
GPA00_RS04375	COG1185	polyribonucleotide nucleotidyltransferase activity
GPA00_RS04385	COG1045	serine acetyltransferase
GPA00_RS04395	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPA00_RS04420	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPA00_RS04445	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GPA00_RS04465	COG1674	ftsk spoiiie
GPA00_RS04520	COG3830	Belongs to the UPF0237 family
GPA00_RS04525	COG2848	UPF0210 protein
GPA00_RS04530	COG0588	phosphoglycerate mutase activity
GPA00_RS04535	COG1876	peptidase activity
GPA00_RS04555	COG0443	Heat shock 70 kDa protein
GPA00_RS04580	COG0351	phosphomethylpyrimidine kinase
GPA00_RS04595	COG0668	transmembrane transport
GPA00_RS04610	COG0504	CTP synthase activity
GPA00_RS04625	COG0191	fructose-bisphosphate aldolase activity
GPA00_RS04635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GPA00_RS04645	COG1461	Dihydroxyacetone kinase
GPA00_RS04650	COG0129	dihydroxy-acid dehydratase activity
GPA00_RS04655	COG0028	Belongs to the TPP enzyme family
GPA00_RS04660	COG0440	acetolactate synthase activity
GPA00_RS04670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GPA00_RS04685	COG1126	abc transporter atp-binding protein
GPA00_RS04690	COG0765	amino acid transport
GPA00_RS04710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPA00_RS04720	COG0719	Fe-S assembly protein
GPA00_RS04725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPA00_RS04740	COG1686	Belongs to the peptidase S11 family
GPA00_RS04745	COG4166	transmembrane transport
GPA00_RS04750	COG0601	transmembrane transport
GPA00_RS04755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPA00_RS04760	COG0444	Belongs to the ABC transporter superfamily
GPA00_RS04765	COG4608	Belongs to the ABC transporter superfamily
GPA00_RS04800	COG0527	aspartate kinase activity
GPA00_RS04805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPA00_RS04810	COG1024	Enoyl-CoA hydratase
GPA00_RS04820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPA00_RS04830	COG2070	2-Nitropropane dioxygenase
GPA00_RS04835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GPA00_RS04840	COG1028	Short-chain dehydrogenase reductase Sdr
GPA00_RS04845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPA00_RS04860	COG0439	Biotin carboxylase
GPA00_RS04875	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPA00_RS04885	COG3716	PTS system mannose fructose sorbose family IID component
GPA00_RS04890	COG3715	PTS system
GPA00_RS04900	COG0561	phosphatase activity
GPA00_RS04915	COG2252	PERMEase
GPA00_RS04920	COG0802	atpase or kinase
GPA00_RS04930	COG1316	TRANSCRIPTIONal
GPA00_RS04940	COG0537	adenosine 5'-monophosphoramidase activity
GPA00_RS04945	COG1131	(ABC) transporter
GPA00_RS04950	COG4473	ABC transporter
GPA00_RS04960	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPA00_RS04970	COG5001	Diguanylate cyclase
GPA00_RS04970	COG3300	MHYT domain
GPA00_RS04975	COG0463	Glycosyl transferase, family 2
GPA00_RS04995	COG0195	Participates in both transcription termination and antitermination
GPA00_RS05000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GPA00_RS05010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPA00_RS05015	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPA00_RS05020	COG1611	Belongs to the LOG family
GPA00_RS05035	COG2217	Heavy metal translocating P-type atpase
GPA00_RS05045	COG2860	membrane
GPA00_RS05050	COG0561	phosphatase activity
GPA00_RS05075	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPA00_RS05110	COG1131	(ABC) transporter
GPA00_RS05120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPA00_RS05125	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPA00_RS05130	COG0275	rRNA processing
GPA00_RS05140	COG0768	penicillin binding
GPA00_RS05150	COG0513	Belongs to the DEAD box helicase family
GPA00_RS05165	COG1126	abc transporter atp-binding protein
GPA00_RS05175	COG0492	ferredoxin-NADP+ reductase activity
GPA00_RS05180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPA00_RS05185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPA00_RS05190	COG3579	cysteine-type endopeptidase activity
GPA00_RS05195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPA00_RS05200	COG3331	DNA recombination
GPA00_RS05210	COG3599	regulation of cell shape
GPA00_RS05220	COG0116	Belongs to the methyltransferase superfamily
GPA00_RS05235	COG1854	S-ribosylhomocysteine lyase activity
GPA00_RS05255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPA00_RS05265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPA00_RS05265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPA00_RS05275	COG2815	serine threonine protein kinase
GPA00_RS05275	COG0515	serine threonine protein kinase
GPA00_RS05285	COG4585	Histidine kinase
GPA00_RS05290	COG2197	response regulator
GPA00_RS05300	COG1098	S1 RNA binding domain
GPA00_RS05310	COG1739	Uncharacterized protein family UPF0029
GPA00_RS05315	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GPA00_RS05320	COG1040	competence protein
GPA00_RS05390	COG3557	Belongs to the UPF0374 family
GPA00_RS05395	COG2137	regulation of response to DNA damage stimulus
GPA00_RS05405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPA00_RS05420	COG1428	Deoxynucleoside kinase
GPA00_RS05440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPA00_RS05475	COG0742	ribosomal rna small subunit methyltransferase
GPA00_RS05480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPA00_RS05485	COG3480	Lon protease (S16) C-terminal proteolytic domain
GPA00_RS05495	COG0737	Belongs to the 5'-nucleotidase family
GPA00_RS05500	COG4470	Protein conserved in bacteria
GPA00_RS05515	COG1132	(ABC) transporter
GPA00_RS05520	COG1132	(ABC) transporter
GPA00_RS05525	COG1131	(ABC) transporter
GPA00_RS05535	COG4585	Histidine kinase
GPA00_RS05540	COG2197	response regulator
GPA00_RS05550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPA00_RS05555	COG0512	Glutamine amidotransferase of anthranilate synthase
GPA00_RS05565	COG0134	indole-3-glycerol-phosphate synthase activity
GPA00_RS05570	COG0135	phosphoribosylanthranilate isomerase activity
GPA00_RS05575	COG0133	tryptophan synthase activity
GPA00_RS05580	COG0159	tryptophan synthase activity
GPA00_RS05585	COG1914	H( )-stimulated, divalent metal cation uptake system
GPA00_RS05595	COG0783	Belongs to the Dps family
GPA00_RS05605	COG1940	carbohydrate kinase activity
GPA00_RS05610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPA00_RS05615	COG1217	gtp-binding protein TYPA
GPA00_RS05650	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPA00_RS05655	COG1799	cell septum assembly
GPA00_RS05670	COG3599	regulation of cell shape
GPA00_RS05690	COG0542	response to heat
GPA00_RS05695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPA00_RS05700	COG4703	Protein of unknown function (DUF1797)
GPA00_RS05705	COG0765	amino acid transport
GPA00_RS05710	COG1126	abc transporter atp-binding protein
GPA00_RS05720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GPA00_RS05720	COG1918	ferrous iron import across plasma membrane
GPA00_RS05730	COG2205	protein histidine kinase activity
GPA00_RS05735	COG0745	RESPONSE REGULATOR receiver
GPA00_RS05775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPA00_RS05805	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GPA00_RS05810	COG1438	arginine binding
GPA00_RS05815	COG0497	DNA recombination
GPA00_RS05820	COG1307	EDD domain protein, DegV family
GPA00_RS05825	COG2755	lipolytic protein G-D-S-L family
GPA00_RS05830	COG4698	Protein conserved in bacteria
GPA00_RS05845	COG3104	oligopeptide transport
GPA00_RS05850	COG0167	dihydroorotate dehydrogenase activity
GPA00_RS05855	COG0640	Transcriptional regulator
GPA00_RS05860	COG2217	Heavy metal translocating P-type atpase
GPA00_RS05865	COG0588	phosphoglycerate mutase activity
GPA00_RS05870	COG1827	regulation of RNA biosynthetic process
GPA00_RS05880	COG0768	penicillin binding
GPA00_RS05885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPA00_RS05900	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPA00_RS05910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPA00_RS05925	COG0513	Belongs to the DEAD box helicase family
GPA00_RS05940	COG2169	Transcriptional regulator
GPA00_RS05955	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPA00_RS05960	COG0204	Acyl-transferase
GPA00_RS05965	COG1596	polysaccharide export
GPA00_RS05965	COG1555	photosystem II stabilization
GPA00_RS05970	COG2333	competence protein COMEC
GPA00_RS05970	COG0658	competence protein
GPA00_RS05985	COG0217	transcriptional regulatory protein
GPA00_RS05990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPA00_RS06000	COG1136	(ABC) transporter
GPA00_RS06005	COG0577	efflux transmembrane transporter activity
GPA00_RS06020	COG0363	glucosamine-6-phosphate deaminase activity
GPA00_RS06025	COG1187	pseudouridine synthase activity
GPA00_RS06045	COG0546	phosphoglycolate phosphatase activity
GPA00_RS06050	COG4122	O-methyltransferase activity
GPA00_RS06055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPA00_RS06060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPA00_RS06065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPA00_RS06070	COG0436	Aminotransferase
GPA00_RS06090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GPA00_RS06095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPA00_RS06100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPA00_RS06105	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPA00_RS06110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPA00_RS06110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPA00_RS06120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPA00_RS06120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPA00_RS06130	COG3859	Proton-coupled thiamine transporter YuaJ
GPA00_RS06140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPA00_RS06145	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPA00_RS06150	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GPA00_RS06155	COG0372	Belongs to the citrate synthase family
GPA00_RS06185	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPA00_RS06225	COG0066	3-isopropylmalate dehydratase activity
GPA00_RS06230	COG1956	GAF domain-containing protein
GPA00_RS06235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPA00_RS06250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPA00_RS06255	COG3708	Transcriptional regulator
GPA00_RS06255	COG2207	Transcriptional regulator
GPA00_RS06260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPA00_RS06265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPA00_RS06270	COG4109	DRTGG domain
GPA00_RS06275	COG0024	Methionine aminopeptidase
GPA00_RS06285	COG2246	polysaccharide biosynthetic process
GPA00_RS06290	COG4708	membrane
GPA00_RS06295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPA00_RS06300	COG1597	lipid kinase activity
GPA00_RS06350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPA00_RS06365	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPA00_RS06380	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GPA00_RS06385	COG1074	ATP-dependent DNA helicase activity
GPA00_RS06415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPA00_RS06430	COG0300	oxidoreductase activity
GPA00_RS06435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPA00_RS06435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GPA00_RS06440	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GPA00_RS06450	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPA00_RS06460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPA00_RS06465	COG2384	SAM-dependent methyltransferase
GPA00_RS06475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPA00_RS06485	COG1088	dTDP-glucose 4,6-dehydratase activity
GPA00_RS06500	COG1051	belongs to the nudix hydrolase family
GPA00_RS06505	COG0628	permease
GPA00_RS06510	COG0457	Tetratricopeptide repeat
GPA00_RS06520	COG0028	Belongs to the TPP enzyme family
GPA00_RS06525	COG3527	Alpha-acetolactate decarboxylase
GPA00_RS06530	COG0531	amino acid
GPA00_RS06535	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GPA00_RS06540	COG0583	DNA-binding transcription factor activity
GPA00_RS06545	COG1126	abc transporter atp-binding protein
GPA00_RS06550	COG0765	amino acid transport
GPA00_RS06560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPA00_RS06565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPA00_RS06570	COG4187	Peptidase family M20/M25/M40
GPA00_RS06585	COG3842	ATPase activity
GPA00_RS06605	COG0488	(ABC) transporter
GPA00_RS06615	COG1132	(ABC) transporter
GPA00_RS06620	COG1132	(ABC) transporter
GPA00_RS06630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GPA00_RS06635	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPA00_RS06635	COG0022	dehydrogenase e1 component
GPA00_RS06650	COG0697	spore germination
GPA00_RS06655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPA00_RS06660	COG0095	Lipoate-protein ligase
GPA00_RS06665	COG0583	DNA-binding transcription factor activity
GPA00_RS06675	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GPA00_RS06715	COG1937	Protein conserved in bacteria
GPA00_RS06725	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPA00_RS06735	COG1418	mRNA catabolic process
GPA00_RS06750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GPA00_RS06760	COG0583	DNA-binding transcription factor activity
GPA00_RS06765	COG1028	Short-chain dehydrogenase reductase Sdr
GPA00_RS06780	COG0789	Transcriptional regulator
GPA00_RS06785	COG0656	L-ascorbic acid biosynthetic process
GPA00_RS06830	COG1136	(ABC) transporter
GPA00_RS06835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPA00_RS06845	COG0583	DNA-binding transcription factor activity
GPA00_RS06850	COG2855	membrane
GPA00_RS06855	COG0322	excinuclease ABC activity
GPA00_RS06880	COG1573	uracil-dna glycosylase
GPA00_RS06885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPA00_RS06905	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GPA00_RS06915	COG0813	purine-nucleoside phosphorylase activity
GPA00_RS06925	COG1316	TRANSCRIPTIONal
GPA00_RS06940	COG0489	protein tyrosine kinase activity
GPA00_RS06945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPA00_RS06955	COG0438	transferase activity, transferring glycosyl groups
GPA00_RS07000	COG2244	polysaccharide biosynthetic process
GPA00_RS07015	COG1091	dTDP-4-dehydrorhamnose reductase activity
GPA00_RS07030	COG0167	dihydroorotate dehydrogenase activity
GPA00_RS07035	COG0284	orotidine-5'-phosphate decarboxylase activity
GPA00_RS07045	COG1881	PFAM PEBP family protein
GPA00_RS07065	COG0187	DNA topoisomerase II activity
GPA00_RS07070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPA00_RS07075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPA00_RS07095	COG0539	negative regulation of cytoplasmic translation
GPA00_RS07105	COG1346	cytolysis
GPA00_RS07110	COG1380	Effector of murein hydrolase LrgA
GPA00_RS07115	COG0398	Pfam SNARE associated Golgi protein
GPA00_RS07130	COG1131	(ABC) transporter
GPA00_RS07135	COG1725	Transcriptional regulator
GPA00_RS07145	COG0205	6-phosphofructokinase activity
GPA00_RS07150	COG0469	pyruvate kinase activity
GPA00_RS07155	COG0681	Belongs to the peptidase S26 family
GPA00_RS07160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GPA00_RS07165	COG2824	Alkylphosphonate utilization operon protein PhnA
GPA00_RS07170	COG0765	amino acid transport
GPA00_RS07175	COG1126	abc transporter atp-binding protein
GPA00_RS07185	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPA00_RS07190	COG1115	amino acid carrier protein
GPA00_RS07195	COG2723	6-phospho-beta-galactosidase activity
GPA00_RS07205	COG0406	alpha-ribazole phosphatase activity
GPA00_RS07210	COG0628	permease
GPA00_RS07230	COG1104	cysteine desulfurase activity
GPA00_RS07240	COG4116	CYTH
GPA00_RS07245	COG2357	RelA SpoT domain protein
GPA00_RS07255	COG0564	pseudouridine synthase activity
GPA00_RS07260	COG0280	phosphate acetyltransferase
GPA00_RS07270	COG0433	COG0433 Predicted ATPase
GPA00_RS07275	COG4221	oxidoreductase activity
GPA00_RS07285	COG2723	6-phospho-beta-galactosidase activity
GPA00_RS07290	COG1136	(ABC) transporter
GPA00_RS07295	COG0577	efflux transmembrane transporter activity
GPA00_RS07300	COG0516	GMP reductase activity
GPA00_RS07310	COG2233	PERMEase
GPA00_RS07335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPA00_RS07340	COG2890	protein-(glutamine-N5) methyltransferase activity
GPA00_RS07345	COG0009	L-threonylcarbamoyladenylate synthase
GPA00_RS07370	COG1132	(ABC) transporter
GPA00_RS07385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPA00_RS07385	COG0519	Catalyzes the synthesis of GMP from XMP
GPA00_RS07460	COG1396	sequence-specific DNA binding
GPA00_RS07465	COG0366	Alpha amylase catalytic
GPA00_RS07465	COG5263	repeat protein
GPA00_RS07480	COG1461	Dihydroxyacetone kinase
GPA00_RS07485	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GPA00_RS07500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPA00_RS07525	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GPA00_RS07530	COG0732	type I restriction modification DNA specificity domain
GPA00_RS07545	COG2188	Transcriptional regulator
GPA00_RS07555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPA00_RS07590	COG1129	ABC transporter
GPA00_RS07595	COG4974	Belongs to the 'phage' integrase family
GPA00_RS07600	COG5002	protein histidine kinase activity
GPA00_RS07605	COG0745	RESPONSE REGULATOR receiver
GPA00_RS07610	COG0577	efflux transmembrane transporter activity
GPA00_RS07615	COG1136	(ABC) transporter
GPA00_RS07640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPA00_RS07645	COG0758	DNA mediated transformation
GPA00_RS07650	COG0110	maltose O-acetyltransferase activity
GPA00_RS07655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPA00_RS07660	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPA00_RS07675	COG0488	(ABC) transporter
GPA00_RS07690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPA00_RS07695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPA00_RS07700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPA00_RS07710	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GPA00_RS07715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPA00_RS07730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPA00_RS07735	COG4684	Psort location CytoplasmicMembrane, score
GPA00_RS07740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPA00_RS07755	COG0346	lactoylglutathione lyase activity
GPA00_RS07760	COG3764	Sortase (surface protein transpeptidase)
GPA00_RS07780	COG1079	Belongs to the binding-protein-dependent transport system permease family
GPA00_RS07785	COG4603	Belongs to the binding-protein-dependent transport system permease family
GPA00_RS07790	COG3845	ABC transporter
GPA00_RS07795	COG1744	ABC transporter substrate-binding protein PnrA-like
GPA00_RS07805	COG2813	Specifically methylates the guanine in position
GPA00_RS07810	COG1072	(Pantothenic acid kinase))
GPA00_RS07820	COG5002	protein histidine kinase activity
GPA00_RS07825	COG0745	RESPONSE REGULATOR receiver
GPA00_RS07835	COG0704	Plays a role in the regulation of phosphate uptake
GPA00_RS07840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPA00_RS07845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPA00_RS07850	COG0581	inorganic phosphate transmembrane transporter activity
GPA00_RS07855	COG0573	inorganic phosphate transmembrane transporter activity
GPA00_RS07865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPA00_RS07865	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPA00_RS07870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPA00_RS07890	COG0483	inositol monophosphate 1-phosphatase activity
GPA00_RS07895	COG4476	Belongs to the UPF0223 family
GPA00_RS07900	COG1393	Belongs to the ArsC family
GPA00_RS07905	COG0196	riboflavin kinase activity
GPA00_RS07910	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPA00_RS07940	COG1136	(ABC) transporter
GPA00_RS07940	COG0577	efflux transmembrane transporter activity
GPA00_RS07945	COG2873	o-acetylhomoserine
GPA00_RS07955	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPA00_RS07965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPA00_RS08000	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GPA00_RS08010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPA00_RS08015	COG1115	amino acid carrier protein
GPA00_RS08020	COG0561	phosphatase activity
GPA00_RS08030	COG2723	6-phospho-beta-galactosidase activity
GPA00_RS08045	COG0561	phosphatase activity
GPA00_RS08050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA00_RS08060	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPA00_RS08065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA00_RS08065	COG3711	transcriptional antiterminator
GPA00_RS08070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPA00_RS08090	COG4095	Psort location CytoplasmicMembrane, score
GPA00_RS08095	COG2723	6-phospho-beta-galactosidase activity
GPA00_RS08110	COG2207	Transcriptional regulator
GPA00_RS08115	COG1263	PTS System
GPA00_RS08115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPA00_RS08115	COG2190	(PTS) system
GPA00_RS08135	COG1177	transmembrane transport
GPA00_RS08140	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPA00_RS08150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPA00_RS08175	COG0285	dihydrofolate synthase activity
GPA00_RS08185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPA00_RS08190	COG2962	Rard protein
GPA00_RS08220	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPA00_RS08235	COG2040	homocysteine
GPA00_RS08240	COG0833	amino acid
GPA00_RS08250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPA00_RS08260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPA00_RS08270	COG3425	synthase
GPA00_RS08285	COG1272	protein, Hemolysin III
GPA00_RS08315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA00_RS08320	COG1126	abc transporter atp-binding protein
GPA00_RS08325	COG4215	(ABC) transporter
GPA00_RS08330	COG0765	amino acid transport
GPA00_RS08335	COG1126	abc transporter atp-binding protein
GPA00_RS08340	COG0765	amino acid transport
GPA00_RS08345	COG0765	amino acid transport
GPA00_RS08350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA00_RS08360	COG0583	DNA-binding transcription factor activity
GPA00_RS08365	COG0656	L-ascorbic acid biosynthetic process
GPA00_RS08385	COG0745	RESPONSE REGULATOR receiver
GPA00_RS08390	COG2357	RelA SpoT domain protein
GPA00_RS08410	COG1132	(ABC) transporter
GPA00_RS08425	COG0242	peptide deformylase activity
GPA00_RS08430	COG1214	PFAM Peptidase M22, glycoprotease
GPA00_RS08430	COG0456	acetyltransferase
GPA00_RS08435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GPA00_RS08450	COG0720	synthase
GPA00_RS08455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPA00_RS08460	COG1132	(ABC) transporter
GPA00_RS08470	COG0488	(ABC) transporter
GPA00_RS08475	COG0617	tRNA 3'-terminal CCA addition
GPA00_RS08495	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPA00_RS08495	COG1388	LysM domain
GPA00_RS08500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPA00_RS08505	COG0646	methionine synthase
GPA00_RS08505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPA00_RS08510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPA00_RS08515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPA00_RS08515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPA00_RS08515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPA00_RS08520	COG1105	Belongs to the carbohydrate kinase PfkB family
GPA00_RS08525	COG1349	DNA-binding transcription factor activity
GPA00_RS08530	COG0492	ferredoxin-NADP+ reductase activity
GPA00_RS08535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPA00_RS08540	COG0336	Belongs to the RNA methyltransferase TrmD family
GPA00_RS08545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPA00_RS08560	COG1837	Belongs to the UPF0109 family
GPA00_RS08585	COG0577	efflux transmembrane transporter activity
GPA00_RS08590	COG1136	(ABC) transporter
GPA00_RS08605	COG0505	Belongs to the CarA family
GPA00_RS08610	COG0540	Belongs to the ATCase OTCase family
GPA00_RS08625	COG0564	pseudouridine synthase activity
GPA00_RS08635	COG0583	DNA-binding transcription factor activity
GPA00_RS08640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GPA00_RS08665	COG0301	tRNA thio-modification
GPA00_RS08670	COG1104	cysteine desulfurase activity
GPA00_RS08680	COG0285	dihydrofolate synthase activity
GPA00_RS08695	COG0287	Prephenate dehydrogenase
GPA00_RS08705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPA00_RS08710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPA00_RS08720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPA00_RS08725	COG1368	sulfuric ester hydrolase activity
GPA00_RS08730	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPA00_RS08735	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GPA00_RS08740	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPA00_RS08745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPA00_RS08765	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPA00_RS08785	COG3942	CHAP domain
GPA00_RS08790	COG0463	Glycosyl transferase, family 2
GPA00_RS08795	COG0438	transferase activity, transferring glycosyl groups
GPA00_RS08805	COG1368	sulfuric ester hydrolase activity
GPA00_RS08810	COG1442	glycosyl transferase family 8
GPA00_RS08810	COG1216	Glycosyl transferase, family 2
GPA00_RS08830	COG1216	Glycosyl transferase, family 2
GPA00_RS08860	COG0463	Glycosyl transferase, family 2
GPA00_RS08875	COG0444	Belongs to the ABC transporter superfamily
GPA00_RS08880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPA00_RS08885	COG0601	transmembrane transport
GPA00_RS08890	COG4166	transmembrane transport
GPA00_RS08895	COG2151	metal-sulfur cluster biosynthetic enzyme
GPA00_RS08900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPA00_RS08905	COG0358	DNA primase activity
GPA00_RS08910	COG1970	mechanosensitive ion channel activity
GPA00_RS08930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPA00_RS08940	COG0058	SHG alpha-glucan phosphorylase activity
GPA00_RS08945	COG1640	4-alpha-glucanotransferase
GPA00_RS08950	COG1609	Transcriptional regulator
GPA00_RS08960	COG1175	transmembrane transport
GPA00_RS08965	COG3833	ABC-type maltose transport systems, permease component
GPA00_RS08970	COG2816	NAD+ diphosphatase activity
GPA00_RS08985	COG0765	amino acid transport
GPA00_RS08990	COG1126	abc transporter atp-binding protein
GPA00_RS08995	COG1592	Rubrerythrin
GPA00_RS09000	COG0488	(ABC) transporter
GPA00_RS09020	COG1187	pseudouridine synthase activity
GPA00_RS09025	COG4166	transmembrane transport
GPA00_RS09030	COG4166	transmembrane transport
GPA00_RS09035	COG0659	secondary active sulfate transmembrane transporter activity
GPA00_RS09060	COG0456	acetyltransferase
GPA00_RS09075	COG1131	(ABC) transporter
GPA00_RS09095	COG2211	Major facilitator Superfamily
GPA00_RS09120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPA00_RS09125	COG1316	TRANSCRIPTIONal
GPA00_RS09130	COG0077	Prephenate dehydratase
GPA00_RS09135	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPA00_RS09140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPA00_RS09145	COG0481	GTPase activity
GPA00_RS09160	COG1518	maintenance of DNA repeat elements
GPA00_RS09190	COG0647	UMP catabolic process
GPA00_RS09200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPA00_RS09215	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPA00_RS09220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPA00_RS09225	COG3442	glutamine amidotransferase
GPA00_RS09235	COG0148	phosphopyruvate hydratase activity
GPA00_RS09250	COG0366	Alpha amylase catalytic
GPA00_RS09250	COG1874	Beta-galactosidase
GPA00_RS09265	COG0107	imidazoleglycerol-phosphate synthase activity
GPA00_RS09275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPA00_RS09285	COG0560	Phosphoserine phosphatase
GPA00_RS09290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPA00_RS09300	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GPA00_RS09315	COG0187	DNA topoisomerase II activity
GPA00_RS09325	COG0772	Belongs to the SEDS family
GPA00_RS09340	COG0038	chloride channel
GPA00_RS09345	COG1605	Chorismate mutase
GPA00_RS09345	COG0287	Prephenate dehydrogenase
GPA00_RS09410	COG4974	Belongs to the 'phage' integrase family
GPA00_RS09455	COG4974	Belongs to the 'phage' integrase family
GPA00_RS09505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPA00_RS09650	COG2003	Belongs to the UPF0758 family
GPA00_RS09675	COG3764	Sortase (surface protein transpeptidase)