locus-tag	class	description
H1R75_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H1R75_RS00015	ENOG4105CBD	Diacylglycerol kinase
H1R75_RS00025	ENOG4105C3G	gtp-binding protein
H1R75_RS00035	ENOG4108JA2	transcriptioN-repair coupling factor
H1R75_RS00040	ENOG41082I2	s4 domain protein
H1R75_RS00070	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H1R75_RS00245	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
H1R75_RS00255	ENOG41068JE	domain protein
H1R75_RS00265	ENOG4105CHM	Aminotransferase
H1R75_RS00275	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
H1R75_RS00280	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H1R75_RS00285	ENOG4105C8V	SAICAR synthetase
H1R75_RS00295	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
H1R75_RS00300	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
H1R75_RS00305	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
H1R75_RS00315	ENOG4105C12	Phosphoribosylglycinamide synthetase
H1R75_RS00320	ENOG4105EWC	Purine nucleoside phosphorylase
H1R75_RS00325	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
H1R75_RS00330	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
H1R75_RS00335	ENOG4105C83	adenylosuccinate lyase
H1R75_RS00345	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
H1R75_RS00350	ENOG4105KJF	protein tyrosine phosphatase
H1R75_RS00360	ENOG4105EXC	Acyl-transferase
H1R75_RS00365	ENOG4105D98	threonine synthase
H1R75_RS00370	ENOG4105UQX	Mate efflux family protein
H1R75_RS00385	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
H1R75_RS00415	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
H1R75_RS00420	ENOG41082SA	50s ribosomal protein l29
H1R75_RS00435	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
H1R75_RS00445	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
H1R75_RS00465	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
H1R75_RS00470	ENOG4105VPB	50S ribosomal protein L30
H1R75_RS00480	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
H1R75_RS00505	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
H1R75_RS00510	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H1R75_RS00515	ENOG4108ZT0	50S ribosomal protein l17
H1R75_RS00625	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
H1R75_RS00635	ENOG4105FDK	ABC transporter
H1R75_RS00680	ENOG4107Y5K	Resolvase
H1R75_RS00745	ENOG4108UUM	single-stranded DNA-binding protein
H1R75_RS00955	ENOG4106855	Competence protein
H1R75_RS00990	ENOG41067QW	Transcriptional regulator
H1R75_RS01005	ENOG4105II7	pyrroline-5-carboxylate reductase
H1R75_RS01010	ENOG4105CN9	Peptidase m42 family protein
H1R75_RS01025	ENOG4108VDD	TRNA binding domain protein
H1R75_RS01035	ENOG410667J	hydrolase
H1R75_RS01040	ENOG4105D7K	pfkb domain protein
H1R75_RS01050	ENOG4105BZU	Histidine kinase
H1R75_RS01055	ENOG4105WH1	Two component transcriptional regulator luxr family
H1R75_RS01075	ENOG4105ETZ	PTS System
H1R75_RS01080	ENOG4105F3R	pts system mannose fructose sorbose family iid
H1R75_RS01090	ENOG4105C7J	ABC transporter, permease
H1R75_RS01095	ENOG4105D7T	ABC transporter
H1R75_RS01110	ENOG4105WT3	Transcriptional regulator
H1R75_RS01125	ENOG4108YBP	pseudouridine synthase
H1R75_RS01135	ENOG4105BZ4	penicillin-binding protein
H1R75_RS01175	ENOG4105CHR	reductase
H1R75_RS01180	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H1R75_RS01185	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
H1R75_RS01190	ENOG4105CJ1	ABC, transporter
H1R75_RS01205	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
H1R75_RS01225	ENOG4105EYW	Ion transport protein
H1R75_RS01230	ENOG4108NRW	Phospholipase, patatin family
H1R75_RS01285	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
H1R75_RS01290	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
H1R75_RS01330	ENOG4105D1H	recombination factor protein RarA
H1R75_RS01335	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
H1R75_RS01350	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
H1R75_RS01355	ENOG4105ETE	Transcriptional regulator (LacI family
H1R75_RS01365	ENOG4105CI1	PTS System
H1R75_RS01380	ENOG4105DER	m42 family
H1R75_RS01390	ENOG4105VZJ	PTS System
H1R75_RS01395	ENOG4105VCP	PTS System
H1R75_RS01400	ENOG4105CS2	ec 3.2.1.21
H1R75_RS01405	ENOG4105CK1	PTS System
H1R75_RS01410	ENOG4108TZY	GntR Family Transcriptional Regulator
H1R75_RS01415	ENOG4105DG6	mannose-6-phosphate isomerase
H1R75_RS01425	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
H1R75_RS01430	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
H1R75_RS01440	ENOG4108TZY	GntR Family Transcriptional Regulator
H1R75_RS01445	ENOG41066F8	ROK family
H1R75_RS01470	ENOG4108IJ9	(ABC) transporter
H1R75_RS01505	ENOG4105CID	antiterminator
H1R75_RS01510	ENOG4105CS2	ec 3.2.1.21
H1R75_RS01515	ENOG4105VCP	PTS System
H1R75_RS01520	ENOG4105CK1	PTS System
H1R75_RS01530	ENOG4108R6W	Transcriptional regulator, ARAC family
H1R75_RS01535	ENOG4105DME	alpha-galactosidase
H1R75_RS01540	ENOG4107YY3	extracellular solute-binding protein family 1
H1R75_RS01555	ENOG4107RK0	Sucrose phosphorylase
H1R75_RS01560	ENOG4105CG3	alpha amylase, catalytic region
H1R75_RS01590	ENOG4105CQ4	Transcriptional regulator
H1R75_RS01595	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
H1R75_RS01605	ENOG4105CMR	udp-glucose 4-epimerase
H1R75_RS01615	ENOG4105VIE	preprotein translocase, subunit YajC
H1R75_RS01620	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H1R75_RS01625	ENOG4105KNE	Phosphatidate cytidylyltransferase
H1R75_RS01650	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
H1R75_RS01675	ENOG4105C0A	alcohol dehydrogenase
H1R75_RS01685	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
H1R75_RS01695	ENOG4105D7W	serine acetyltransferase
H1R75_RS01705	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H1R75_RS01710	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H1R75_RS01720	ENOG4105EPR	degv family
H1R75_RS01730	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
H1R75_RS01750	ENOG41068JE	domain protein
H1R75_RS01800	ENOG4106BHR	ftsk SpoIIIE family protein
H1R75_RS01815	ENOG41067QW	Transcriptional regulator
H1R75_RS01830	ENOG4105C4X	radical SAM domain protein
H1R75_RS01845	ENOG4105BZ1	(ABC) transporter
H1R75_RS01850	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H1R75_RS01890	ENOG4105BZ1	(ABC) transporter
H1R75_RS01895	ENOG4105CJA	serine threonine protein kinase
H1R75_RS01900	ENOG4105CUG	Oligopeptidase b
H1R75_RS01905	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H1R75_RS01960	ENOG4105VUC	UPF0237 protein
H1R75_RS01965	ENOG4105CAG	UPF0210 protein
H1R75_RS01970	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H1R75_RS01975	ENOG4108VXD	carboxy-peptidase
H1R75_RS01980	ENOG4107X35	defense response to bacterium
H1R75_RS02020	ENOG4105DWF	phosphomethylpyrimidine kinase
H1R75_RS02035	ENOG4105D8X	mechanosensitive ion channel
H1R75_RS02050	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
H1R75_RS02065	ENOG4105D2N	Aldolase
H1R75_RS02075	ENOG4105VB9	50S ribosomal protein l28
H1R75_RS02085	ENOG4105DP4	dak2 domain fusion protein ylov
H1R75_RS02090	ENOG4105C01	Dihydroxy-acid dehydratase
H1R75_RS02100	ENOG4108ZP8	Acetolactate synthase small subunit
H1R75_RS02110	ENOG4105C7B	Threonine dehydratase
H1R75_RS02125	ENOG4105CDA	abc transporter atp-binding protein
H1R75_RS02130	ENOG4105E5Q	amino acid AbC transporter
H1R75_RS02150	ENOG4105ESV	Glycosyl transferase, family 4
H1R75_RS02160	ENOG4105JRK	feS assembly protein SufD
H1R75_RS02170	ENOG4108UNV	SUF system FeS assembly protein, NifU family
H1R75_RS02185	ENOG4108J59	Extracellular solute-binding protein, family 5
H1R75_RS02190	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H1R75_RS02195	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H1R75_RS02205	ENOG4108JQ7	(ABC) transporter
H1R75_RS02240	ENOG4105CFH	Aspartokinase
H1R75_RS02245	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
H1R75_RS02250	ENOG4105CGU	Enoyl-CoA hydratase
H1R75_RS02260	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
H1R75_RS02270	ENOG4105EA8	2-Nitropropane dioxygenase
H1R75_RS02275	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
H1R75_RS02280	ENOG4105CHR	reductase
H1R75_RS02285	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H1R75_RS02300	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H1R75_RS02315	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
H1R75_RS02325	ENOG4105F3R	pts system mannose fructose sorbose family iid
H1R75_RS02330	ENOG4105ETZ	PTS System
H1R75_RS02340	ENOG4108KP7	hydrolase
H1R75_RS02355	ENOG4105C7N	Xanthine uracil vitamin C permease
H1R75_RS02360	ENOG4105K8N	protein family UPF0079, ATPase
H1R75_RS02370	ENOG4108KGH	TRANSCRIPTIONal
H1R75_RS02380	ENOG4105K59	histidine triad (HIT) protein
H1R75_RS02400	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
H1R75_RS02410	ENOG4105BZU	Histidine kinase
H1R75_RS02415	ENOG4105CKK	Glycosyl transferase, family 2
H1R75_RS02435	ENOG4105CHV	Transcription elongation factor NusA
H1R75_RS02440	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
H1R75_RS02450	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
H1R75_RS02455	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
H1R75_RS02460	ENOG4108URH	decarboxylase
H1R75_RS02470	ENOG4105NA0	Transcriptional regulator
H1R75_RS02475	ENOG4105C59	p-type ATPase
H1R75_RS02485	ENOG4105EN6	Membrane
H1R75_RS02490	ENOG410667J	hydrolase
H1R75_RS02500	ENOG4108S8M	degv family
H1R75_RS02520	ENOG4105CE4	GlcNAc 6-P deacetylase
H1R75_RS02550	ENOG4105CJ1	ABC, transporter
H1R75_RS02565	ENOG4105CS2	ec 3.2.1.21
H1R75_RS02570	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
H1R75_RS02575	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
H1R75_RS02580	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
H1R75_RS02590	ENOG4105CJN	penicillin-binding protein
H1R75_RS02600	ENOG4105C1J	atp-dependent rna helicase
H1R75_RS02605	ENOG4105EAB	amino acid AbC transporter
H1R75_RS02610	ENOG4108HW4	amino acid AbC transporter
H1R75_RS02615	ENOG4105CDA	abc transporter atp-binding protein
H1R75_RS02625	ENOG4105C3M	thioredoxin reductase
H1R75_RS02630	ENOG4105DAP	Nicotinate phosphoribosyltransferase
H1R75_RS02635	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
H1R75_RS02640	ENOG4105CTZ	aminopeptidase c
H1R75_RS02645	ENOG4105BZ4	penicillin-binding protein
H1R75_RS02650	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
H1R75_RS02660	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
H1R75_RS02670	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
H1R75_RS02675	ENOG41070VT	
H1R75_RS02680	ENOG4105CHR	reductase
H1R75_RS02685	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
H1R75_RS02705	ENOG4105C25	Primosomal protein n'
H1R75_RS02715	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H1R75_RS02725	ENOG4105D9P	serine threonine protein kinase
H1R75_RS02735	ENOG4105ENE	Histidine kinase
H1R75_RS02740	ENOG4105WH1	Two component transcriptional regulator luxr family
H1R75_RS02760	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
H1R75_RS02770	ENOG41081UC	Inherit from COG: Competence protein
H1R75_RS02840	ENOG4105EVI	UPF0374 protein
H1R75_RS02845	ENOG410902V	Modulates RecA activity (By similarity)
H1R75_RS02855	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H1R75_RS02870	ENOG4105ZMH	deoxynucleoside kinase
H1R75_RS02905	ENOG4105DVF	Cytosine-specific methyltransferase
H1R75_RS02940	ENOG4106H78	methyltransferase
H1R75_RS02945	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
H1R75_RS02950	ENOG41063PX	domain protein
H1R75_RS02960	ENOG4107R8B	5'-nucleotidase
H1R75_RS02965	ENOG4105MMD	transcriptional regulator
H1R75_RS02980	ENOG4105BZ1	(ABC) transporter
H1R75_RS02985	ENOG4105BZ1	(ABC) transporter
H1R75_RS02990	ENOG4108M15	ABC transporter
H1R75_RS03000	ENOG4105BZU	Histidine kinase
H1R75_RS03005	ENOG4108S01	response regulator
H1R75_RS03015	ENOG4105CRQ	synthase (Component I)
H1R75_RS03020	ENOG4105DDQ	anthranilate synthase
H1R75_RS03030	ENOG4105DK0	Indole-3-glycerol phosphate synthase
H1R75_RS03035	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
H1R75_RS03040	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
H1R75_RS03045	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
H1R75_RS03050	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
H1R75_RS03060	ENOG4105HUF	DNA protection during starvation protein
H1R75_RS03070	ENOG4105DKQ	ROK family
H1R75_RS03075	ENOG4105WZW	rhodanese family
H1R75_RS03080	ENOG4105CI3	gtp-binding protein typa
H1R75_RS03115	ENOG4105DFA	alanine racemase domain protein
H1R75_RS03120	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
H1R75_RS03135	ENOG4105MMF	Cell division protein DIVIVA
H1R75_RS03155	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H1R75_RS03165	ENOG4107IN1	Protein of unknown function (DUF1797)
H1R75_RS03170	ENOG4105E5Q	amino acid AbC transporter
H1R75_RS03185	ENOG4105CE1	Ferrous iron transport protein b
H1R75_RS03195	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
H1R75_RS03200	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H1R75_RS03235	ENOG4105DX0	Hemolysin A
H1R75_RS03240	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
H1R75_RS03245	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
H1R75_RS03250	ENOG4108RCR	degv family
H1R75_RS03255	ENOG41090WU	lipolytic protein G-D-S-L family
H1R75_RS03260	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
H1R75_RS03335	ENOG4108PNI	recT protein
H1R75_RS03530	ENOG41068JE	domain protein
H1R75_RS03540	ENOG4105DUX	Transporter
H1R75_RS03550	ENOG4107YCR	Transcriptional regulator, ARSR family
H1R75_RS03555	ENOG4105C59	p-type ATPase
H1R75_RS03560	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H1R75_RS03570	ENOG4105RNB	
H1R75_RS03575	ENOG4107RF6	penicillin-binding protein
H1R75_RS03580	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
H1R75_RS03585	ENOG4105CPF	Cell wall formation (By similarity)
H1R75_RS03595	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
H1R75_RS03610	ENOG4105C1J	atp-dependent rna helicase
H1R75_RS03640	ENOG41060K3	Methyltransferase
H1R75_RS03645	ENOG4105F6E	Acyl-transferase
H1R75_RS03650	ENOG4105KQC	Competence protein
H1R75_RS03655	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
H1R75_RS03660	ENOG4105TQK	DNA polymerase iii, delta' subunit
H1R75_RS03675	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
H1R75_RS03710	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H1R75_RS03720	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
H1R75_RS03725	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
H1R75_RS03730	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
H1R75_RS03750	ENOG4105BZ1	(ABC) transporter
H1R75_RS03765	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
H1R75_RS03775	ENOG4105C8Y	Acetylornithine aminotransferase
H1R75_RS03780	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
H1R75_RS03785	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
H1R75_RS03795	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
H1R75_RS03805	ENOG41084PM	thiamine transporter
H1R75_RS03815	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H1R75_RS03820	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
H1R75_RS03825	ENOG4108I0Z	Aconitate hydratase
H1R75_RS03830	ENOG4105BZN	citrate synthase
H1R75_RS03835	ENOG4108HMX	isocitrate dehydrogenase (NADP)
H1R75_RS03845	ENOG4105KRI	phosphocarrier protein (HPr
H1R75_RS03850	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H1R75_RS03860	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
H1R75_RS03900	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H1R75_RS03910	ENOG4105C6E	dna polymerase iii
H1R75_RS03925	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
H1R75_RS03935	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H1R75_RS03960	ENOG4105WH5	Teichoic acid glycosylation protein
H1R75_RS03965	ENOG410807C	QueT transporter
H1R75_RS03970	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
H1R75_RS03975	ENOG4105CBD	Diacylglycerol kinase
H1R75_RS03980	ENOG4105ZA1	atp synthase
H1R75_RS04005	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
H1R75_RS04015	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
H1R75_RS04025	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H1R75_RS04035	ENOG4105ZT7	DNA-entry nuclease
H1R75_RS04040	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
H1R75_RS04055	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H1R75_RS04060	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
H1R75_RS04090	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H1R75_RS04105	ENOG4108IXY	short-chain dehydrogenase reductase
H1R75_RS04110	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
H1R75_RS04115	ENOG4107QHE	Choloylglycine hydrolase
H1R75_RS04125	ENOG4105CVG	Homoserine O-transsuccinylase
H1R75_RS04135	ENOG4105CSM	endonuclease III
H1R75_RS04150	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
H1R75_RS04160	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
H1R75_RS04180	ENOG41068YB	TPR repeat-containing protein
H1R75_RS04195	ENOG4107FQX	Alpha-acetolactate decarboxylase
H1R75_RS04200	ENOG4105CUB	amino acid
H1R75_RS04220	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H1R75_RS04235	ENOG4105C5H	ABC transporter
H1R75_RS04240	ENOG4105WT3	Transcriptional regulator
H1R75_RS04255	ENOG4105BZ1	(ABC) transporter
H1R75_RS04260	ENOG4105BZ1	(ABC) transporter
H1R75_RS04270	ENOG4107RUY	(E1 component), alpha subunit
H1R75_RS04275	ENOG4105CPP	Dehydrogenase, E1 component
H1R75_RS04280	ENOG4105C7S	Dehydrogenase
H1R75_RS04285	ENOG4107QN2	dihydrolipoyl dehydrogenase
H1R75_RS04290	ENOG4108PCN	EamA-like transporter family
H1R75_RS04295	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H1R75_RS04300	ENOG4105DF9	Lipoate-protein, ligase
H1R75_RS04305	ENOG4106P55	Transcriptional regulator
H1R75_RS04315	ENOG4105C87	Aminotransferase class I and II
H1R75_RS04345	ENOG4105ENX	hydrolase
H1R75_RS04355	ENOG4105VPX	protein, conserved in bacteria
H1R75_RS04365	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
H1R75_RS04385	ENOG41081I9	integral membrane protein
H1R75_RS04400	ENOG4105VUF	Transcriptional regulator
H1R75_RS04445	ENOG4107SVH	Potassium channel protein
H1R75_RS04460	ENOG4105HMI	Membrane
H1R75_RS04465	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
H1R75_RS04485	ENOG4108RG0	uracil-dna glycosylase
H1R75_RS04490	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
H1R75_RS04510	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
H1R75_RS04520	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
H1R75_RS04530	ENOG4108KGH	TRANSCRIPTIONal
H1R75_RS04545	ENOG4105D75	Capsular exopolysaccharide family
H1R75_RS04560	ENOG4108KMV	Glycosyl transferase (Group 1
H1R75_RS04595	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
H1R75_RS04605	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
H1R75_RS04620	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
H1R75_RS04635	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
H1R75_RS04640	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
H1R75_RS04645	ENOG4105F0N	pyrophosphate phospho-hydrolase
H1R75_RS04655	ENOG4105KIS	phospholipid-binding protein
H1R75_RS04665	ENOG4105CD3	dihydroorotase
H1R75_RS04675	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H1R75_RS04680	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H1R75_RS04685	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H1R75_RS04705	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H1R75_RS04715	ENOG41067MG	lrgb family
H1R75_RS04720	ENOG4105VAW	lrga family
H1R75_RS04740	ENOG4105CZV	ABC transporter
H1R75_RS04745	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
H1R75_RS04755	ENOG4105CTQ	phosphohexokinase
H1R75_RS04760	ENOG4105CA9	Pyruvate kinase
H1R75_RS04775	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
H1R75_RS04780	ENOG4105E5Q	amino acid AbC transporter
H1R75_RS04785	ENOG4105CDA	abc transporter atp-binding protein
H1R75_RS04805	ENOG4105CS2	ec 3.2.1.21
H1R75_RS04810	ENOG4105CVJ	phosphoglycerate mutase
H1R75_RS04815	ENOG4105C02	permease
H1R75_RS04835	ENOG4105C3J	Cysteine desulfurase
H1R75_RS04845	ENOG4105MIX	Adenylate cyclase
H1R75_RS04860	ENOG4105EMS	pseudouridine synthase
H1R75_RS04865	ENOG4108IJ2	phosphate acetyltransferase
H1R75_RS04870	ENOG4105EMU	Dehydrogenase
H1R75_RS04880	ENOG4105CS2	ec 3.2.1.21
H1R75_RS04890	ENOG4107WD8	ABC transporter, permease
H1R75_RS04895	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
H1R75_RS04905	ENOG4105C2W	permease
H1R75_RS04930	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
H1R75_RS04935	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
H1R75_RS04940	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H1R75_RS04965	ENOG4105BZ1	(ABC) transporter
H1R75_RS04980	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H1R75_RS05015	ENOG4105WT3	Transcriptional regulator
H1R75_RS05040	ENOG4105VDH	Dihydroxyacetone kinase
H1R75_RS05065	ENOG41067QW	Transcriptional regulator
H1R75_RS05075	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H1R75_RS05105	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1R75_RS05135	ENOG4105BZ1	(ABC) transporter
H1R75_RS05165	ENOG4105EWM	Histidine kinase
H1R75_RS05170	ENOG4105CJZ	response regulator
H1R75_RS05205	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
H1R75_RS05210	ENOG4105C79	DNA protecting protein DprA
H1R75_RS05215	ENOG4108UW5	maltose o-acetyltransferase
H1R75_RS05220	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H1R75_RS05225	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
H1R75_RS05240	ENOG4105C5H	ABC transporter
H1R75_RS05260	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H1R75_RS05265	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
H1R75_RS05270	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H1R75_RS05285	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
H1R75_RS05290	ENOG4105FH5	Membrane
H1R75_RS05300	ENOG4105K3M	)-transporter
H1R75_RS05310	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
H1R75_RS05315	ENOG4108Z6X	(sortase) family
H1R75_RS05325	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H1R75_RS05340	ENOG4105UIB	(ABC) transporter
H1R75_RS05345	ENOG4108JQ9	ABC transporter
H1R75_RS05350	ENOG4105DIH	basic membrane
H1R75_RS05360	ENOG4107Y49	methyltransferase
H1R75_RS05365	ENOG4105CS9	pantothenic acid kinase
H1R75_RS05375	ENOG4105US7	Histidine kinase
H1R75_RS05380	ENOG4108STX	response regulator
H1R75_RS05390	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
H1R75_RS05395	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H1R75_RS05400	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H1R75_RS05405	ENOG4105E2Z	phosphate ABC transporter (Permease
H1R75_RS05410	ENOG4105C8U	phosphate abc transporter
H1R75_RS05420	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H1R75_RS05425	ENOG4105DC8	reductase
H1R75_RS05445	ENOG4105ECY	inositol monophosphatase
H1R75_RS05455	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
H1R75_RS05460	ENOG4105DTN	riboflavin biosynthesis protein ribF
H1R75_RS05465	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
H1R75_RS05485	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H1R75_RS05500	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
H1R75_RS05510	ENOG4105JH5	thiaminase II
H1R75_RS05535	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
H1R75_RS05545	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H1R75_RS05550	ENOG4105BZG	amino acid carrier protein
H1R75_RS05555	ENOG4108HCJ	Hydrolase
H1R75_RS05565	ENOG4105CS2	ec 3.2.1.21
H1R75_RS05575	ENOG4108HCJ	Hydrolase
H1R75_RS05580	ENOG4108HCJ	Hydrolase
H1R75_RS05585	ENOG4105CK1	PTS System
H1R75_RS05595	ENOG4105VCP	PTS System
H1R75_RS05600	ENOG4105EMD	TRANSCRIPTIONal
H1R75_RS05605	ENOG4105VZJ	PTS System
H1R75_RS05625	ENOG4105W3H	MtN3 and saliva related transmembrane protein
H1R75_RS05630	ENOG4105CS2	ec 3.2.1.21
H1R75_RS05645	ENOG41075H3	AraC family transcriptional regulator
H1R75_RS05650	ENOG4105C5Y	PTS System
H1R75_RS05665	ENOG4108HM4	ABC transporter
H1R75_RS05670	ENOG4105D38	putrescine abc transporter
H1R75_RS05675	ENOG4105F38	ABC transporter, permease
H1R75_RS05685	ENOG4105D4A	Cell wall formation (By similarity)
H1R75_RS05710	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H1R75_RS05720	ENOG4105FR1	rard protein
H1R75_RS05730	ENOG4105D6E	homoserine dehydrogenase
H1R75_RS05755	ENOG4108VZM	50s ribosomal protein L10
H1R75_RS05770	ENOG4108J5H	Homocysteine s-methyltransferase
H1R75_RS05775	ENOG4108IQI	permease
H1R75_RS05785	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H1R75_RS05790	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
H1R75_RS05800	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
H1R75_RS05815	ENOG4108UT2	hemolysin iii
H1R75_RS05840	ENOG4105CDA	abc transporter atp-binding protein
H1R75_RS05865	ENOG4107R11	Transcriptional regulator
H1R75_RS05870	ENOG4105CV8	reductase
H1R75_RS05880	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H1R75_RS05905	ENOG4105BZ1	(ABC) transporter
H1R75_RS05920	ENOG4107YDN	peptide deformylase
H1R75_RS05925	ENOG4108Z7F	N-acetyltransferase
H1R75_RS05930	ENOG4107R37	Glutamate dehydrogenase
H1R75_RS05945	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
H1R75_RS05950	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
H1R75_RS05955	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
H1R75_RS05960	ENOG4105BZ1	(ABC) transporter
H1R75_RS05970	ENOG4105C5H	ABC transporter
H1R75_RS05975	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
H1R75_RS05985	ENOG4105EPR	degv family
H1R75_RS05995	ENOG4107X35	defense response to bacterium
H1R75_RS06000	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
H1R75_RS06020	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
H1R75_RS06025	ENOG4105CPC	Aldo Keto reductase
H1R75_RS06050	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
H1R75_RS06055	ENOG4105DM4	PTS System
H1R75_RS06060	ENOG4105DE4	1-phosphofructokinase
H1R75_RS06065	ENOG4105MVE	transcriptional regulator
H1R75_RS06070	ENOG4105CAY	ferredoxin--nadp reductase
H1R75_RS06075	ENOG4105RHY	Pfam:UPF0157
H1R75_RS06085	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
H1R75_RS06100	ENOG4105VB6	UPF0109 protein
H1R75_RS06125	ENOG4107RBB	ABC transporter, permease
H1R75_RS06130	ENOG4105C19	ABC transporter
H1R75_RS06145	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
H1R75_RS06150	ENOG4105CXT	aspartate transcarbamylase
H1R75_RS06160	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
H1R75_RS06165	ENOG4105C34	Pseudouridine synthase
H1R75_RS06175	ENOG4107R11	Transcriptional regulator
H1R75_RS06180	ENOG4105K46	50S ribosomal protein l27
H1R75_RS06205	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
H1R75_RS06210	ENOG4105C3J	Cysteine desulfurase
H1R75_RS06220	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H1R75_RS06235	ENOG4105EVN	Prephenate dehydrogenase
H1R75_RS06245	ENOG4105D49	3-dehydroquinate synthase
H1R75_RS06250	ENOG4105E2X	shikimate dehydrogenase
H1R75_RS06260	ENOG4105DR4	Methyltransferase
H1R75_RS06270	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
H1R75_RS06275	ENOG4105VJV	50s ribosomal protein L35
H1R75_RS06280	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
H1R75_RS06285	ENOG4105CAT	Cytidine monophosphate kinase
H1R75_RS06305	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
H1R75_RS06320	ENOG4107T7U	Sulfatase
H1R75_RS06325	ENOG41068JE	domain protein
H1R75_RS06330	ENOG4105CKK	Glycosyl transferase, family 2
H1R75_RS06340	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
H1R75_RS06350	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
H1R75_RS06360	ENOG4105EY8	ABC transporter
H1R75_RS06370	ENOG4105K64	Glycosyl transferase, family 2
H1R75_RS06380	ENOG4108JQ7	(ABC) transporter
H1R75_RS06385	ENOG4105C3U	ABC transporter
H1R75_RS06390	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H1R75_RS06395	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H1R75_RS06400	ENOG4105DIB	Oligopeptide-binding protein
H1R75_RS06405	ENOG4105VG1	fes assembly suf system protein
H1R75_RS06410	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H1R75_RS06415	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H1R75_RS06420	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
H1R75_RS06440	ENOG4106PMH	Extracellular solute-binding protein family 3
H1R75_RS06450	ENOG4107R0W	ABC transporter
H1R75_RS06455	ENOG4106PMH	Extracellular solute-binding protein family 3
H1R75_RS06460	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
H1R75_RS06465	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
H1R75_RS06470	ENOG4105FKQ	transcriptional regulator
H1R75_RS06485	ENOG4105EG2	ABC transporter, permease
H1R75_RS06490	ENOG4105E09	nadh pyrophosphatase
H1R75_RS06500	ENOG4105E5Q	amino acid AbC transporter
H1R75_RS06505	ENOG4105CDA	abc transporter atp-binding protein
H1R75_RS06510	ENOG4108RAC	Rubrerythrin
H1R75_RS06515	ENOG4105C5H	ABC transporter
H1R75_RS06540	ENOG4108J59	Extracellular solute-binding protein, family 5
H1R75_RS06545	ENOG4108J59	Extracellular solute-binding protein, family 5
H1R75_RS06555	ENOG4105C5Y	PTS System
H1R75_RS06565	ENOG4105CHH	sulfate transporter
H1R75_RS06595	ENOG4105EPI	acetyltransferase, (GNAT) family
H1R75_RS06630	ENOG4105DA5	(ABC) transporter
H1R75_RS06680	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H1R75_RS06685	ENOG4108KGH	TRANSCRIPTIONal
H1R75_RS06690	ENOG4105CQC	Prephenate dehydratase
H1R75_RS06695	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
H1R75_RS06700	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
H1R75_RS06705	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
H1R75_RS06735	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
H1R75_RS06745	ENOG4105CSA	Coproporphyrinogen iii oxidase
H1R75_RS06760	ENOG4105C8B	TIGR00159 family
H1R75_RS06765	ENOG4105DMS	mur ligase
H1R75_RS06770	ENOG4105F1K	Glutamine amidotransferase
H1R75_RS06780	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
H1R75_RS06795	ENOG4108IUM	Glycogen debranching enzyme
H1R75_RS06810	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
H1R75_RS06820	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
H1R75_RS06830	ENOG4105EAC	phosphoserine phosphatase
H1R75_RS06835	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
H1R75_RS06845	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
H1R75_RS06860	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H1R75_RS06885	ENOG4107R4J	Chloride channel
H1R75_RS06890	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
H1R75_RS06900	ENOG4105NQC	Flavodoxin
H1R75_RS06910	ENOG4105C0A	alcohol dehydrogenase
H1R75_RS06915	ENOG4105SFS	phosphoesterase RecJ domain protein
H1R75_RS06925	ENOG4107R08	Integrase
H1R75_RS06985	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
H1R75_RS06995	ENOG4105ST3	Transcriptional regulator
H1R75_RS07010	ENOG4105KME	endoribonuclease L-psp
H1R75_RS07030	ENOG4105C5S	asparaginyl-tRNA synthetase
H1R75_RS07040	ENOG4105CHM	Aminotransferase
H1R75_RS07050	ENOG4105DVT	helicase
H1R75_RS07065	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
H1R75_RS07070	ENOG4105CAK	Cell division ATP-binding protein ftsE
H1R75_RS07080	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
H1R75_RS07100	ENOG4105DCI	Phosphohydrolase
H1R75_RS07125	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H1R75_RS07130	ENOG4105CNI	cell division protein FtsW
H1R75_RS07140	ENOG4105DPN	Oligoendopeptidase f
H1R75_RS07145	ENOG4108V06	Glutathione peroxidase
H1R75_RS07165	ENOG4108TGR	phosphatase
H1R75_RS07215	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H1R75_RS07235	ENOG4105VEM	Conserved domain protein
H1R75_RS07245	ENOG4105CFP	Peptidase U32
H1R75_RS07275	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
H1R75_RS07285	ENOG410906U	SprT-like
H1R75_RS07300	ENOG4108PJD	permease
H1R75_RS07305	ENOG4108NNR	transporter substrate-binding protein
H1R75_RS07315	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
H1R75_RS07320	ENOG410667J	hydrolase
H1R75_RS07325	ENOG4108HCJ	Hydrolase
H1R75_RS07335	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
H1R75_RS07345	ENOG4105Q2H	domain protein
H1R75_RS07350	ENOG4105BZU	Histidine kinase
H1R75_RS07355	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H1R75_RS07360	ENOG4105CDA	abc transporter atp-binding protein
H1R75_RS07365	ENOG4107RP9	extracellular solute-binding protein, family 3
H1R75_RS07370	ENOG4105EAD	ABC transporter
H1R75_RS07375	ENOG4105DRP	amino acid AbC transporter
H1R75_RS07390	ENOG4105BZU	Histidine kinase
H1R75_RS07395	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H1R75_RS07410	ENOG4105CCI	Myosin-Cross-Reactive Antigen
H1R75_RS07420	ENOG4105C22	threonyL-tRNA synthetase
H1R75_RS07425	ENOG4105BZF	Glycosyl transferase (Group 1
H1R75_RS07430	ENOG4105W2C	Glycosyl transferase
H1R75_RS07435	ENOG4105ETE	Transcriptional regulator (LacI family
H1R75_RS07440	ENOG4105DC7	peptidase M24
H1R75_RS07450	ENOG4105E09	nadh pyrophosphatase
H1R75_RS07460	ENOG4108UQV	Membrane
H1R75_RS07465	ENOG4105KST	dependent repressor
H1R75_RS07480	ENOG4108RCM	Nitroreductase
H1R75_RS07485	ENOG4105DC8	reductase
H1R75_RS07495	ENOG4105K56	Transcriptional regulator
H1R75_RS07505	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
H1R75_RS07530	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
H1R75_RS07540	ENOG4107YR5	Diacylglycerol kinase
H1R75_RS07545	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
H1R75_RS07565	ENOG4105C9A	Phoh family
H1R75_RS07570	ENOG4106E6V	UPF0346 protein
H1R75_RS07580	ENOG4105QNR	S1 RNA binding domain protein
H1R75_RS07610	ENOG4105CNU	cell division protein FtsK
H1R75_RS07640	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
H1R75_RS07665	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
H1R75_RS07680	ENOG4105K7K	Transcriptional regulator
H1R75_RS07705	ENOG41082YX	Transcriptional regulator, arsr family
H1R75_RS07710	ENOG4105CGK	Exodeoxyribonuclease III
H1R75_RS07720	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H1R75_RS07740	ENOG41080E8	Transcriptional regulator, Spx MgsR family
H1R75_RS07745	ENOG4108JQ1	Dehydrogenase
H1R75_RS07760	ENOG4108YZA	Nitrogen regulatory protein pii
H1R75_RS07765	ENOG4105BZU	Histidine kinase
H1R75_RS07770	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
H1R75_RS07780	ENOG4105MA4	psp1 domain protein
H1R75_RS07785	ENOG4105FA2	dna polymerase iii
H1R75_RS07795	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H1R75_RS07800	ENOG4108IV0	ABC, transporter
H1R75_RS07805	ENOG4105C0Z	ABC transporter
H1R75_RS07810	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
H1R75_RS07815	ENOG4105C32	Amino acid ABC transporter (Permease)
H1R75_RS07820	ENOG4105CP9	extracellular ligand-binding receptor
H1R75_RS07825	ENOG4105WUC	UPF0298 protein
H1R75_RS07845	ENOG4105CR8	Transcriptional regulator
H1R75_RS07850	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
H1R75_RS07855	ENOG4105C87	Aminotransferase class I and II
H1R75_RS07860	ENOG4105C28	cystathionine
H1R75_RS07885	ENOG4105DQ5	transport system permease protein
H1R75_RS07890	ENOG4105EHG	Permease protein
H1R75_RS07905	ENOG4105D1Q	UPF0246 protein
H1R75_RS07925	ENOG4105F1A	Pyruvate formate-lyase
H1R75_RS07935	ENOG4107RBJ	symporter
H1R75_RS07940	ENOG4105DKW	ABC transporter
H1R75_RS07950	ENOG4105N5T	Radical SAM Protein
H1R75_RS07955	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
H1R75_RS07960	ENOG4108SAX	Membrane
H1R75_RS07970	ENOG4105C0X	amino acid
H1R75_RS07975	ENOG4105C1A	potassium transporter peripheral membrane
H1R75_RS07980	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
H1R75_RS07985	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
H1R75_RS08005	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
H1R75_RS08020	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H1R75_RS08025	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
H1R75_RS08040	ENOG4105HFZ	Membrane
H1R75_RS08050	ENOG4108RWN	rrna methyltransferase
H1R75_RS08060	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
H1R75_RS08115	ENOG4105GR3	Histidine kinase
H1R75_RS08120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H1R75_RS08130	ENOG4105D0M	Protease HtpX homolog
H1R75_RS08135	ENOG4108V0P	LemA family
H1R75_RS08150	ENOG4107ZYR	domain protein
H1R75_RS08160	ENOG4108JJB	ABC transporter
H1R75_RS08170	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
H1R75_RS08180	ENOG4108UMI	ABC transporter, permease
H1R75_RS08190	ENOG4105D01	(LipO)protein
H1R75_RS08215	ENOG4105CDY	transcriptional regulatory protein
H1R75_RS08220	ENOG4107TXC	Transcriptional regulator
H1R75_RS08225	ENOG4105CDE	UPF0348 protein
H1R75_RS08235	ENOG4105WAB	arsR family transcriptional regulator
H1R75_RS08245	ENOG4105DXX	methyltransferase
H1R75_RS08250	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
H1R75_RS08255	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
H1R75_RS08260	ENOG4108WF2	Metal Dependent Phosphohydrolase
H1R75_RS08265	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H1R75_RS08270	ENOG410812S	Rna-binding protein
H1R75_RS08275	ENOG4105CQW	ribosome biogenesis GTPase YqeH
H1R75_RS08280	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
H1R75_RS08290	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H1R75_RS08300	ENOG4108UZ3	Transporter
H1R75_RS08315	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H1R75_RS08320	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H1R75_RS08330	ENOG4105CHM	Aminotransferase
H1R75_RS08340	ENOG4107YZX	Universal stress protein
H1R75_RS08350	ENOG4107RB3	L-asparaginase
H1R75_RS08355	ENOG4105VMP	Transcriptional regulator
H1R75_RS08375	ENOG4105CB5	ATP-dependent DNA helicase recG
H1R75_RS08390	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
H1R75_RS08395	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
H1R75_RS08405	ENOG4105EVU	fructokinase
H1R75_RS08410	ENOG4105C5Y	PTS System
H1R75_RS08420	ENOG4105ETE	Transcriptional regulator (LacI family
H1R75_RS08425	ENOG4105M7K	Involved in the transcription termination process (By similarity)
H1R75_RS08435	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H1R75_RS08445	ENOG4108UK2	deaminase
H1R75_RS08450	ENOG4105DC7	peptidase M24
H1R75_RS08480	ENOG4105VMP	Transcriptional regulator
H1R75_RS08490	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
H1R75_RS08535	ENOG4105CEN	a g-specific adenine glycosylase
H1R75_RS08540	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
H1R75_RS08570	ENOG4105K63	Thioredoxin
H1R75_RS08580	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
H1R75_RS08590	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
H1R75_RS08615	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H1R75_RS08620	ENOG4105C3F	Signal peptidase i
H1R75_RS08640	ENOG4105C6N	Formate acetyltransferase
H1R75_RS08665	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
H1R75_RS08670	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
H1R75_RS08680	ENOG4107TXC	Transcriptional regulator
H1R75_RS08695	ENOG4105CBX	hi0933 family
H1R75_RS08710	ENOG410801F	ribosomal-protein-alanine acetyltransferase
H1R75_RS08715	ENOG41072GX	Peptidase M22 Glycoprotease
H1R75_RS08720	ENOG4106EHS	UPF0356 protein
H1R75_RS08730	ENOG41068JE	domain protein
H1R75_RS08735	ENOG4105BZ8	glutamate synthase
H1R75_RS08740	ENOG4105CBC	glutamate synthase
H1R75_RS08745	ENOG4105C5F	glutamine synthetase
H1R75_RS08750	ENOG4105KV4	Transcriptional regulator
H1R75_RS08760	ENOG4105BZA	Phosphoglycerate kinase
H1R75_RS08765	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H1R75_RS08770	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
H1R75_RS08775	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
H1R75_RS08785	ENOG4105DFT	pur operon repressor
H1R75_RS08800	ENOG4105FJ0	thiamine
H1R75_RS08805	ENOG4105DJV	ribulose-phosphate 3-epimerase
H1R75_RS08830	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
H1R75_RS08835	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
H1R75_RS08875	ENOG4108TYN	CAAX amino terminal protease family protein
H1R75_RS08905	ENOG4105F8V	Hydrolase, tatD family
H1R75_RS08915	ENOG4105C6K	Malic enzyme
H1R75_RS08920	ENOG4107ZGM	malolactic fermentation system
H1R75_RS08925	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
H1R75_RS08930	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
H1R75_RS08935	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
H1R75_RS08950	ENOG4105US7	Histidine kinase
H1R75_RS08955	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H1R75_RS08960	ENOG41075H3	AraC family transcriptional regulator
H1R75_RS08975	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
H1R75_RS09000	ENOG4108RZ2	Glycoside hydrolase family 16
H1R75_RS09035	ENOG4105CJ1	ABC, transporter
H1R75_RS09050	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
H1R75_RS09060	ENOG4105CDH	Citrulline--aspartate ligase
H1R75_RS09065	ENOG4105DJ2	Major Facilitator Superfamily
H1R75_RS09070	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
H1R75_RS09075	ENOG4107RGM	aldo keto reductase
H1R75_RS09090	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
H1R75_RS09095	ENOG4105WPN	DNA integration recombination invertion protein
H1R75_RS09105	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
H1R75_RS09115	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
H1R75_RS09125	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
H1R75_RS09130	ENOG4107QYV	phosphohexose isomerase
H1R75_RS09145	ENOG4108RQ5	Beta-lactamase domain-containing protein
H1R75_RS09150	ENOG41080Y5	BioY family
H1R75_RS09160	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
H1R75_RS09175	ENOG4105K4P	CoA-binding domain protein
H1R75_RS09180	ENOG4105C2M	dna polymerase I
H1R75_RS09220	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H1R75_RS09225	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H1R75_RS09240	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
H1R75_RS09255	ENOG4105WT3	Transcriptional regulator
H1R75_RS09260	ENOG4105C9K	Endothelin-converting enzyme 1
H1R75_RS09280	ENOG4105C3F	Signal peptidase i
H1R75_RS09290	ENOG41082JN	Transcriptional regulator
H1R75_RS09295	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
H1R75_RS09330	ENOG4105VBH	UPF0297 protein
H1R75_RS09335	ENOG410888K	transcriptional regulator, Spx
H1R75_RS09345	ENOG4105CEV	competence damage-inducible protein
H1R75_RS09355	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H1R75_RS09380	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
H1R75_RS09390	ENOG4105C5Y	PTS System
H1R75_RS09395	ENOG4108JYZ	YitT family
H1R75_RS09400	ENOG4107AYK	membrAne
H1R75_RS09430	ENOG4105CG3	alpha amylase, catalytic region
H1R75_RS09435	ENOG4105C5Y	PTS System
H1R75_RS09440	ENOG4107414	GntR family transcriptional regulator
H1R75_RS09520	ENOG4105EC2	ftsk spoIIIe
H1R75_RS09525	ENOG4108MGT	Required for secretion of EsxA and EsxB
H1R75_RS09540	ENOG410646G	Proteins of 100 residues with WXG
H1R75_RS09560	ENOG4105ECB	domain protein
H1R75_RS09560	ENOG4105ECB	domain protein
H1R75_RS09565	ENOG4105ST3	Transcriptional regulator
H1R75_RS09575	ENOG4105W42	Veg protein
H1R75_RS09580	ENOG4105CDU	Replicative dna helicase
H1R75_RS09610	ENOG4105EJQ	L-serine dehydratase
H1R75_RS09615	ENOG4107XGZ	Hydrolase
H1R75_RS09620	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
H1R75_RS09635	ENOG4108JJB	ABC transporter
H1R75_RS09640	ENOG4108JJB	ABC transporter
H1R75_RS09645	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
H1R75_RS09670	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
H1R75_RS09680	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H1R75_RS09695	ENOG4105C5H	ABC transporter
H1R75_RS09700	ENOG4105EJV	Membrane
H1R75_RS09725	ENOG4105C0H	protease
H1R75_RS09730	ENOG4105FA0	parb-like partition protein