locus-tag	class	description
H1R75_RS00010	COG0592	DNA-directed DNA polymerase activity
H1R75_RS00015	COG1597	lipid kinase activity
H1R75_RS00025	COG0012	GTP binding
H1R75_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1R75_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1R75_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1R75_RS00245	COG1792	Involved in formation and maintenance of cell shape
H1R75_RS00255	COG3942	CHAP domain
H1R75_RS00265	COG0436	Aminotransferase
H1R75_RS00275	COG0416	fatty acid biosynthetic process
H1R75_RS00280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1R75_RS00285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H1R75_RS00290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1R75_RS00300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H1R75_RS00305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1R75_RS00315	COG0151	Belongs to the GarS family
H1R75_RS00320	COG1683	Conserved Protein
H1R75_RS00325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H1R75_RS00335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1R75_RS00345	COG2255	four-way junction helicase activity
H1R75_RS00350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1R75_RS00360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H1R75_RS00360	COG2755	lipolytic protein G-D-S-L family
H1R75_RS00370	COG0534	Mate efflux family protein
H1R75_RS00375	COG0051	transcription antitermination factor activity, RNA binding
H1R75_RS00385	COG0088	Forms part of the polypeptide exit tunnel
H1R75_RS00390	COG0089	rRNA binding
H1R75_RS00415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H1R75_RS00420	COG0255	Belongs to the universal ribosomal protein uL29 family
H1R75_RS00435	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H1R75_RS00445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H1R75_RS00465	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H1R75_RS00470	COG1841	ribosomal large subunit assembly
H1R75_RS00480	COG0201	protein transport
H1R75_RS00505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H1R75_RS00510	COG0202	RNA polymerase activity
H1R75_RS00515	COG0203	ribosomal protein L17
H1R75_RS00625	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H1R75_RS00635	COG1121	(ABC) transporter
H1R75_RS00640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1R75_RS00660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H1R75_RS00670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1R75_RS00675	COG1459	type II secretion system
H1R75_RS00680	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1R75_RS00745	COG0629	single-stranded DNA binding
H1R75_RS00955	COG4537	Required for transformation and DNA binding
H1R75_RS00980	COG0827	DNA restriction-modification system
H1R75_RS01005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H1R75_RS01010	COG1363	Peptidase, m42
H1R75_RS01020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1R75_RS01025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1R75_RS01035	COG0561	phosphatase activity
H1R75_RS01040	COG5492	domain, Protein
H1R75_RS01040	COG3583	domain protein
H1R75_RS01040	COG1621	beta-fructofuranosidase activity
H1R75_RS01050	COG4585	Histidine kinase
H1R75_RS01055	COG2197	response regulator
H1R75_RS01075	COG3715	PTS system
H1R75_RS01080	COG3716	PTS system mannose fructose sorbose family IID component
H1R75_RS01090	COG4120	Belongs to the binding-protein-dependent transport system permease family
H1R75_RS01095	COG1116	anion transmembrane transporter activity
H1R75_RS01095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1R75_RS01110	COG1396	sequence-specific DNA binding
H1R75_RS01125	COG0564	pseudouridine synthase activity
H1R75_RS01135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1R75_RS01175	COG1028	Short-chain dehydrogenase reductase Sdr
H1R75_RS01180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1R75_RS01185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H1R75_RS01190	COG1131	(ABC) transporter
H1R75_RS01205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H1R75_RS01225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1R75_RS01230	COG4667	esterase of the alpha-beta hydrolase superfamily
H1R75_RS01285	COG2017	converts alpha-aldose to the beta-anomer
H1R75_RS01290	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1R75_RS01295	COG0681	Belongs to the peptidase S26 family
H1R75_RS01330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1R75_RS01335	COG0456	acetyltransferase
H1R75_RS01350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1R75_RS01355	COG1609	Transcriptional regulator
H1R75_RS01365	COG2190	(PTS) system
H1R75_RS01365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R75_RS01365	COG1263	PTS System
H1R75_RS01380	COG1363	Peptidase, m42
H1R75_RS01390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1R75_RS01395	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1R75_RS01400	COG2723	6-phospho-beta-galactosidase activity
H1R75_RS01405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1R75_RS01410	COG2188	Transcriptional regulator
H1R75_RS01415	COG1482	cell wall glycoprotein biosynthetic process
H1R75_RS01425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H1R75_RS01430	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H1R75_RS01440	COG2188	Transcriptional regulator
H1R75_RS01445	COG1940	carbohydrate kinase activity
H1R75_RS01470	COG3842	ATPase activity
H1R75_RS01480	COG0698	ribose 5-phosphate isomerase
H1R75_RS01505	COG3711	transcriptional antiterminator
H1R75_RS01510	COG2723	6-phospho-beta-galactosidase activity
H1R75_RS01515	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1R75_RS01520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1R75_RS01520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1R75_RS01525	COG3867	Arabinogalactan endo-beta-1,4-galactanase
H1R75_RS01530	COG2207	Transcriptional regulator
H1R75_RS01535	COG3345	alpha-galactosidase
H1R75_RS01540	COG1653	transport
H1R75_RS01545	COG1175	transmembrane transport
H1R75_RS01550	COG0395	ABC-type sugar transport system, permease component
H1R75_RS01555	COG0366	Alpha amylase catalytic
H1R75_RS01560	COG0366	Alpha amylase catalytic
H1R75_RS01590	COG1609	Transcriptional regulator
H1R75_RS01595	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H1R75_RS01600	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H1R75_RS01605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1R75_RS01615	COG1862	Preprotein translocase
H1R75_RS01620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1R75_RS01625	COG4589	Belongs to the CDS family
H1R75_RS01645	COG1846	Transcriptional regulator
H1R75_RS01650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1R75_RS01675	COG1454	alcohol dehydrogenase
H1R75_RS01675	COG1012	belongs to the aldehyde dehydrogenase family
H1R75_RS01685	COG1185	polyribonucleotide nucleotidyltransferase activity
H1R75_RS01695	COG1045	serine acetyltransferase
H1R75_RS01705	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H1R75_RS01730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H1R75_RS01750	COG3942	CHAP domain
H1R75_RS01765	COG0433	COG0433 Predicted ATPase
H1R75_RS01800	COG1674	ftsk spoiiie
H1R75_RS01815	COG3620	sequence-specific DNA binding
H1R75_RS01830	COG0641	radical SAM
H1R75_RS01845	COG1132	(ABC) transporter
H1R75_RS01850	COG2226	methyltransferase
H1R75_RS01890	COG1132	(ABC) transporter
H1R75_RS01895	COG0515	serine threonine protein kinase
H1R75_RS01900	COG1770	oligopeptidase
H1R75_RS01905	COG0577	efflux transmembrane transporter activity
H1R75_RS01905	COG1136	(ABC) transporter
H1R75_RS01960	COG3830	Belongs to the UPF0237 family
H1R75_RS01965	COG2848	UPF0210 protein
H1R75_RS01970	COG0588	phosphoglycerate mutase activity
H1R75_RS01975	COG1876	peptidase activity
H1R75_RS02020	COG0351	phosphomethylpyrimidine kinase
H1R75_RS02035	COG0668	transmembrane transport
H1R75_RS02050	COG0504	CTP synthase activity
H1R75_RS02065	COG0191	fructose-bisphosphate aldolase activity
H1R75_RS02075	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H1R75_RS02085	COG1461	Dihydroxyacetone kinase
H1R75_RS02090	COG0129	dihydroxy-acid dehydratase activity
H1R75_RS02095	COG0028	Belongs to the TPP enzyme family
H1R75_RS02100	COG0440	acetolactate synthase activity
H1R75_RS02110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1R75_RS02125	COG1126	abc transporter atp-binding protein
H1R75_RS02130	COG0765	amino acid transport
H1R75_RS02150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1R75_RS02160	COG0719	Fe-S assembly protein
H1R75_RS02165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1R75_RS02180	COG1686	Belongs to the peptidase S11 family
H1R75_RS02185	COG4166	transmembrane transport
H1R75_RS02190	COG0601	transmembrane transport
H1R75_RS02195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1R75_RS02205	COG4608	Belongs to the ABC transporter superfamily
H1R75_RS02240	COG0527	aspartate kinase activity
H1R75_RS02245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1R75_RS02250	COG1024	Enoyl-CoA hydratase
H1R75_RS02260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H1R75_RS02270	COG2070	2-Nitropropane dioxygenase
H1R75_RS02275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1R75_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
H1R75_RS02285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1R75_RS02300	COG0439	Biotin carboxylase
H1R75_RS02315	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H1R75_RS02325	COG3716	PTS system mannose fructose sorbose family IID component
H1R75_RS02330	COG3715	PTS system
H1R75_RS02340	COG0561	phosphatase activity
H1R75_RS02355	COG2252	PERMEase
H1R75_RS02360	COG0802	atpase or kinase
H1R75_RS02370	COG1316	TRANSCRIPTIONal
H1R75_RS02380	COG0537	adenosine 5'-monophosphoramidase activity
H1R75_RS02385	COG1131	(ABC) transporter
H1R75_RS02390	COG4473	ABC transporter
H1R75_RS02400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1R75_RS02410	COG2199	diguanylate cyclase activity
H1R75_RS02415	COG0463	Glycosyl transferase, family 2
H1R75_RS02435	COG0195	Participates in both transcription termination and antitermination
H1R75_RS02440	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H1R75_RS02450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H1R75_RS02455	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H1R75_RS02460	COG1611	Belongs to the LOG family
H1R75_RS02475	COG2217	Heavy metal translocating P-type atpase
H1R75_RS02485	COG2860	membrane
H1R75_RS02490	COG0561	phosphatase activity
H1R75_RS02550	COG1131	(ABC) transporter
H1R75_RS02565	COG2723	6-phospho-beta-galactosidase activity
H1R75_RS02570	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H1R75_RS02575	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H1R75_RS02580	COG0275	rRNA processing
H1R75_RS02590	COG0768	penicillin binding
H1R75_RS02600	COG0513	Belongs to the DEAD box helicase family
H1R75_RS02610	COG0765	amino acid transport
H1R75_RS02615	COG1126	abc transporter atp-binding protein
H1R75_RS02625	COG0492	ferredoxin-NADP+ reductase activity
H1R75_RS02630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H1R75_RS02635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1R75_RS02640	COG3579	cysteine-type endopeptidase activity
H1R75_RS02645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1R75_RS02650	COG3331	DNA recombination
H1R75_RS02660	COG3599	regulation of cell shape
H1R75_RS02670	COG0116	Belongs to the methyltransferase superfamily
H1R75_RS02685	COG1854	S-ribosylhomocysteine lyase activity
H1R75_RS02705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1R75_RS02715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H1R75_RS02715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H1R75_RS02725	COG2815	serine threonine protein kinase
H1R75_RS02725	COG0515	serine threonine protein kinase
H1R75_RS02735	COG4585	Histidine kinase
H1R75_RS02740	COG2197	response regulator
H1R75_RS02750	COG1098	S1 RNA binding domain
H1R75_RS02760	COG1739	Uncharacterized protein family UPF0029
H1R75_RS02765	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H1R75_RS02770	COG1040	competence protein
H1R75_RS02840	COG3557	Belongs to the UPF0374 family
H1R75_RS02845	COG2137	regulation of response to DNA damage stimulus
H1R75_RS02855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H1R75_RS02870	COG1428	Deoxynucleoside kinase
H1R75_RS02905	COG0270	DNA (cytosine-5-)-methyltransferase activity
H1R75_RS02940	COG0742	ribosomal rna small subunit methyltransferase
H1R75_RS02945	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H1R75_RS02950	COG3480	Lon protease (S16) C-terminal proteolytic domain
H1R75_RS02960	COG0737	Belongs to the 5'-nucleotidase family
H1R75_RS02965	COG4470	Protein conserved in bacteria
H1R75_RS02980	COG1132	(ABC) transporter
H1R75_RS02985	COG1132	(ABC) transporter
H1R75_RS02990	COG1131	(ABC) transporter
H1R75_RS03000	COG4585	Histidine kinase
H1R75_RS03005	COG2197	response regulator
H1R75_RS03015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1R75_RS03020	COG0512	Glutamine amidotransferase of anthranilate synthase
H1R75_RS03030	COG0134	indole-3-glycerol-phosphate synthase activity
H1R75_RS03035	COG0135	phosphoribosylanthranilate isomerase activity
H1R75_RS03040	COG0133	tryptophan synthase activity
H1R75_RS03045	COG0159	tryptophan synthase activity
H1R75_RS03050	COG1914	H( )-stimulated, divalent metal cation uptake system
H1R75_RS03060	COG0783	Belongs to the Dps family
H1R75_RS03070	COG1940	carbohydrate kinase activity
H1R75_RS03075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1R75_RS03115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H1R75_RS03120	COG1799	cell septum assembly
H1R75_RS03135	COG3599	regulation of cell shape
H1R75_RS03155	COG0542	response to heat
H1R75_RS03160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H1R75_RS03165	COG4703	Protein of unknown function (DUF1797)
H1R75_RS03170	COG0765	amino acid transport
H1R75_RS03185	COG1918	ferrous iron import across plasma membrane
H1R75_RS03185	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H1R75_RS03195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H1R75_RS03200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1R75_RS03235	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H1R75_RS03240	COG1438	arginine binding
H1R75_RS03245	COG0497	DNA recombination
H1R75_RS03250	COG1307	EDD domain protein, DegV family
H1R75_RS03255	COG2755	lipolytic protein G-D-S-L family
H1R75_RS03260	COG4698	Protein conserved in bacteria
H1R75_RS03270	COG0582	viral genome integration into host DNA
H1R75_RS03335	COG3723	Recombinational DNA repair protein, rece pathway
H1R75_RS03540	COG3104	oligopeptide transport
H1R75_RS03545	COG0167	dihydroorotate dehydrogenase activity
H1R75_RS03550	COG0640	Transcriptional regulator
H1R75_RS03555	COG2217	Heavy metal translocating P-type atpase
H1R75_RS03560	COG0588	phosphoglycerate mutase activity
H1R75_RS03565	COG1827	regulation of RNA biosynthetic process
H1R75_RS03575	COG0768	penicillin binding
H1R75_RS03580	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1R75_RS03585	COG1181	Belongs to the D-alanine--D-alanine ligase family
H1R75_RS03595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1R75_RS03610	COG0513	Belongs to the DEAD box helicase family
H1R75_RS03625	COG2169	Transcriptional regulator
H1R75_RS03640	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H1R75_RS03645	COG0204	Acyl-transferase
H1R75_RS03650	COG1555	photosystem II stabilization
H1R75_RS03650	COG1596	polysaccharide export
H1R75_RS03655	COG2333	competence protein COMEC
H1R75_RS03655	COG0658	competence protein
H1R75_RS03660	COG1466	dna polymerase III delta subunit
H1R75_RS03675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H1R75_RS03690	COG1187	pseudouridine synthase activity
H1R75_RS03710	COG0546	phosphoglycolate phosphatase activity
H1R75_RS03715	COG4122	O-methyltransferase activity
H1R75_RS03720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1R75_RS03725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H1R75_RS03730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1R75_RS03735	COG0436	Aminotransferase
H1R75_RS03750	COG1132	(ABC) transporter
H1R75_RS03765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1R75_RS03770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H1R75_RS03775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1R75_RS03780	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1R75_RS03785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1R75_RS03785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1R75_RS03795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1R75_RS03795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1R75_RS03805	COG3859	Proton-coupled thiamine transporter YuaJ
H1R75_RS03815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1R75_RS03820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1R75_RS03825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1R75_RS03830	COG0372	Belongs to the citrate synthase family
H1R75_RS03860	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H1R75_RS03900	COG0066	3-isopropylmalate dehydratase activity
H1R75_RS03905	COG1956	GAF domain-containing protein
H1R75_RS03910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1R75_RS03925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H1R75_RS03935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1R75_RS03945	COG4109	DRTGG domain
H1R75_RS03950	COG0024	Methionine aminopeptidase
H1R75_RS03960	COG2246	polysaccharide biosynthetic process
H1R75_RS03965	COG4708	membrane
H1R75_RS03970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H1R75_RS03975	COG1597	lipid kinase activity
H1R75_RS04025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1R75_RS04040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H1R75_RS04055	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H1R75_RS04060	COG1074	ATP-dependent DNA helicase activity
H1R75_RS04090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1R75_RS04105	COG0300	oxidoreductase activity
H1R75_RS04110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1R75_RS04110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H1R75_RS04115	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
H1R75_RS04125	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H1R75_RS04135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1R75_RS04150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H1R75_RS04160	COG1088	dTDP-glucose 4,6-dehydratase activity
H1R75_RS04170	COG1051	belongs to the nudix hydrolase family
H1R75_RS04175	COG0628	permease
H1R75_RS04180	COG0457	Tetratricopeptide repeat
H1R75_RS04190	COG0028	Belongs to the TPP enzyme family
H1R75_RS04195	COG3527	Alpha-acetolactate decarboxylase
H1R75_RS04200	COG0531	amino acid
H1R75_RS04205	COG1293	RNA-binding protein homologous to eukaryotic snRNP
H1R75_RS04220	COG3842	ATPase activity
H1R75_RS04235	COG0488	(ABC) transporter
H1R75_RS04240	COG1396	sequence-specific DNA binding
H1R75_RS04255	COG1132	(ABC) transporter
H1R75_RS04260	COG1132	(ABC) transporter
H1R75_RS04270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1R75_RS04275	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1R75_RS04275	COG0022	dehydrogenase e1 component
H1R75_RS04290	COG0697	spore germination
H1R75_RS04295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1R75_RS04300	COG0095	Lipoate-protein ligase
H1R75_RS04305	COG0583	DNA-binding transcription factor activity
H1R75_RS04315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H1R75_RS04355	COG1937	Protein conserved in bacteria
H1R75_RS04365	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1R75_RS04375	COG1418	mRNA catabolic process
H1R75_RS04390	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1R75_RS04400	COG0789	Transcriptional regulator
H1R75_RS04405	COG0656	L-ascorbic acid biosynthetic process
H1R75_RS04445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1R75_RS04450	COG1011	Hydrolase
H1R75_RS04460	COG2855	membrane
H1R75_RS04465	COG0322	excinuclease ABC activity
H1R75_RS04485	COG1573	uracil-dna glycosylase
H1R75_RS04490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H1R75_RS04510	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H1R75_RS04520	COG0813	purine-nucleoside phosphorylase activity
H1R75_RS04530	COG1316	TRANSCRIPTIONal
H1R75_RS04545	COG0489	protein tyrosine kinase activity
H1R75_RS04560	COG0438	transferase activity, transferring glycosyl groups
H1R75_RS04595	COG3754	Rhamnan synthesis protein F
H1R75_RS04605	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H1R75_RS04620	COG1091	dTDP-4-dehydrorhamnose reductase activity
H1R75_RS04635	COG0167	dihydroorotate dehydrogenase activity
H1R75_RS04640	COG0284	orotidine-5'-phosphate decarboxylase activity
H1R75_RS04645	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1R75_RS04655	COG1881	PFAM PEBP family protein
H1R75_RS04675	COG0187	DNA topoisomerase II activity
H1R75_RS04680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H1R75_RS04685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1R75_RS04705	COG0539	negative regulation of cytoplasmic translation
H1R75_RS04715	COG1346	cytolysis
H1R75_RS04720	COG1380	Effector of murein hydrolase LrgA
H1R75_RS04725	COG0398	Pfam SNARE associated Golgi protein
H1R75_RS04740	COG1131	(ABC) transporter
H1R75_RS04745	COG1725	Transcriptional regulator
H1R75_RS04755	COG0205	6-phosphofructokinase activity
H1R75_RS04760	COG0469	pyruvate kinase activity
H1R75_RS04775	COG2824	Alkylphosphonate utilization operon protein PhnA
H1R75_RS04780	COG0765	amino acid transport
H1R75_RS04785	COG1126	abc transporter atp-binding protein
H1R75_RS04795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H1R75_RS04805	COG2723	6-phospho-beta-galactosidase activity
H1R75_RS04810	COG0406	alpha-ribazole phosphatase activity
H1R75_RS04815	COG0628	permease
H1R75_RS04835	COG1104	cysteine desulfurase activity
H1R75_RS04845	COG4116	CYTH
H1R75_RS04850	COG2357	RelA SpoT domain protein
H1R75_RS04860	COG0564	pseudouridine synthase activity
H1R75_RS04865	COG0280	phosphate acetyltransferase
H1R75_RS04870	COG4221	oxidoreductase activity
H1R75_RS04880	COG2723	6-phospho-beta-galactosidase activity
H1R75_RS04885	COG1136	(ABC) transporter
H1R75_RS04890	COG0577	efflux transmembrane transporter activity
H1R75_RS04895	COG0516	GMP reductase activity
H1R75_RS04905	COG2233	PERMEase
H1R75_RS04930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H1R75_RS04935	COG2890	protein-(glutamine-N5) methyltransferase activity
H1R75_RS04940	COG0009	L-threonylcarbamoyladenylate synthase
H1R75_RS04965	COG1132	(ABC) transporter
H1R75_RS04980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1R75_RS04980	COG0519	Catalyzes the synthesis of GMP from XMP
H1R75_RS05015	COG1396	sequence-specific DNA binding
H1R75_RS05020	COG0366	Alpha amylase catalytic
H1R75_RS05020	COG5263	repeat protein
H1R75_RS05040	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
H1R75_RS05075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1R75_RS05095	COG2188	Transcriptional regulator
H1R75_RS05105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1R75_RS05135	COG1132	(ABC) transporter
H1R75_RS05165	COG2205	protein histidine kinase activity
H1R75_RS05170	COG0745	RESPONSE REGULATOR receiver
H1R75_RS05175	COG0577	efflux transmembrane transporter activity
H1R75_RS05180	COG1136	(ABC) transporter
H1R75_RS05205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1R75_RS05210	COG0758	DNA mediated transformation
H1R75_RS05215	COG0110	maltose O-acetyltransferase activity
H1R75_RS05220	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1R75_RS05225	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H1R75_RS05240	COG0488	(ABC) transporter
H1R75_RS05255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1R75_RS05260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1R75_RS05265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1R75_RS05270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1R75_RS05285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1R75_RS05290	COG4684	Psort location CytoplasmicMembrane, score
H1R75_RS05295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1R75_RS05310	COG0346	lactoylglutathione lyase activity
H1R75_RS05315	COG3764	Sortase (surface protein transpeptidase)
H1R75_RS05350	COG1744	ABC transporter substrate-binding protein PnrA-like
H1R75_RS05360	COG2813	Specifically methylates the guanine in position
H1R75_RS05365	COG1072	(Pantothenic acid kinase))
H1R75_RS05375	COG5002	protein histidine kinase activity
H1R75_RS05380	COG0745	RESPONSE REGULATOR receiver
H1R75_RS05390	COG0704	Plays a role in the regulation of phosphate uptake
H1R75_RS05395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1R75_RS05400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1R75_RS05405	COG0581	inorganic phosphate transmembrane transporter activity
H1R75_RS05410	COG0573	inorganic phosphate transmembrane transporter activity
H1R75_RS05420	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
H1R75_RS05420	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H1R75_RS05425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1R75_RS05445	COG0483	inositol monophosphate 1-phosphatase activity
H1R75_RS05450	COG4476	Belongs to the UPF0223 family
H1R75_RS05455	COG1393	Belongs to the ArsC family
H1R75_RS05460	COG0196	riboflavin kinase activity
H1R75_RS05465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1R75_RS05485	COG1136	(ABC) transporter
H1R75_RS05485	COG0577	efflux transmembrane transporter activity
H1R75_RS05490	COG2873	o-acetylhomoserine
H1R75_RS05500	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H1R75_RS05510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1R75_RS05535	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
H1R75_RS05545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1R75_RS05550	COG1115	amino acid carrier protein
H1R75_RS05555	COG0561	phosphatase activity
H1R75_RS05565	COG2723	6-phospho-beta-galactosidase activity
H1R75_RS05575	COG0561	phosphatase activity
H1R75_RS05580	COG0561	phosphatase activity
H1R75_RS05585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1R75_RS05595	COG1447	Phosphotransferase system cellobiose-specific component IIA
H1R75_RS05600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R75_RS05600	COG3711	transcriptional antiterminator
H1R75_RS05605	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H1R75_RS05630	COG2723	6-phospho-beta-galactosidase activity
H1R75_RS05645	COG2207	Transcriptional regulator
H1R75_RS05650	COG2190	(PTS) system
H1R75_RS05650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R75_RS05650	COG1263	PTS System
H1R75_RS05670	COG1177	transmembrane transport
H1R75_RS05675	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1R75_RS05685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H1R75_RS05710	COG0285	dihydrofolate synthase activity
H1R75_RS05720	COG2962	Rard protein
H1R75_RS05755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H1R75_RS05770	COG2040	homocysteine
H1R75_RS05775	COG0833	amino acid
H1R75_RS05785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H1R75_RS05790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1R75_RS05800	COG3425	synthase
H1R75_RS05815	COG1272	protein, Hemolysin III
H1R75_RS05840	COG1126	abc transporter atp-binding protein
H1R75_RS05845	COG0765	amino acid transport
H1R75_RS05850	COG0765	amino acid transport
H1R75_RS05855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R75_RS05865	COG0583	DNA-binding transcription factor activity
H1R75_RS05870	COG0656	L-ascorbic acid biosynthetic process
H1R75_RS05880	COG0745	RESPONSE REGULATOR receiver
H1R75_RS05885	COG2357	RelA SpoT domain protein
H1R75_RS05905	COG1132	(ABC) transporter
H1R75_RS05920	COG0242	peptide deformylase activity
H1R75_RS05925	COG1247	-acetyltransferase
H1R75_RS05930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1R75_RS05945	COG0602	queuosine metabolic process
H1R75_RS05950	COG0720	synthase
H1R75_RS05955	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1R75_RS05960	COG1132	(ABC) transporter
H1R75_RS05970	COG0488	(ABC) transporter
H1R75_RS05975	COG0617	tRNA 3'-terminal CCA addition
H1R75_RS05995	COG1705	Flagellar rod assembly protein muramidase FlgJ
H1R75_RS05995	COG1388	LysM domain
H1R75_RS06000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H1R75_RS06020	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1R75_RS06025	COG0667	Aldo Keto reductase
H1R75_RS06050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H1R75_RS06055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R75_RS06055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1R75_RS06055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1R75_RS06060	COG1105	Belongs to the carbohydrate kinase PfkB family
H1R75_RS06065	COG1349	DNA-binding transcription factor activity
H1R75_RS06070	COG0492	ferredoxin-NADP+ reductase activity
H1R75_RS06075	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1R75_RS06085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1R75_RS06100	COG1837	Belongs to the UPF0109 family
H1R75_RS06125	COG0577	efflux transmembrane transporter activity
H1R75_RS06130	COG1136	(ABC) transporter
H1R75_RS06145	COG0505	Belongs to the CarA family
H1R75_RS06150	COG0540	Belongs to the ATCase OTCase family
H1R75_RS06160	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H1R75_RS06165	COG0564	pseudouridine synthase activity
H1R75_RS06175	COG0583	DNA-binding transcription factor activity
H1R75_RS06180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H1R75_RS06205	COG0301	tRNA thio-modification
H1R75_RS06210	COG1104	cysteine desulfurase activity
H1R75_RS06220	COG0285	dihydrofolate synthase activity
H1R75_RS06235	COG0287	Prephenate dehydrogenase
H1R75_RS06245	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H1R75_RS06250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H1R75_RS06260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H1R75_RS06270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H1R75_RS06275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H1R75_RS06280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H1R75_RS06285	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H1R75_RS06305	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1R75_RS06320	COG1368	sulfuric ester hydrolase activity
H1R75_RS06325	COG3942	CHAP domain
H1R75_RS06330	COG0463	Glycosyl transferase, family 2
H1R75_RS06350	COG3754	Rhamnan synthesis protein F
H1R75_RS06370	COG0463	Glycosyl transferase, family 2
H1R75_RS06385	COG0444	Belongs to the ABC transporter superfamily
H1R75_RS06390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1R75_RS06395	COG0601	transmembrane transport
H1R75_RS06400	COG4166	transmembrane transport
H1R75_RS06405	COG2151	metal-sulfur cluster biosynthetic enzyme
H1R75_RS06410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1R75_RS06415	COG0358	DNA primase activity
H1R75_RS06420	COG1970	mechanosensitive ion channel activity
H1R75_RS06445	COG0436	Aminotransferase
H1R75_RS06450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R75_RS06460	COG0058	SHG alpha-glucan phosphorylase activity
H1R75_RS06465	COG1640	4-alpha-glucanotransferase
H1R75_RS06470	COG1609	Transcriptional regulator
H1R75_RS06480	COG1175	transmembrane transport
H1R75_RS06485	COG3833	ABC-type maltose transport systems, permease component
H1R75_RS06490	COG2816	NAD+ diphosphatase activity
H1R75_RS06500	COG0765	amino acid transport
H1R75_RS06505	COG1126	abc transporter atp-binding protein
H1R75_RS06510	COG1592	Rubrerythrin
H1R75_RS06515	COG0488	(ABC) transporter
H1R75_RS06535	COG1187	pseudouridine synthase activity
H1R75_RS06540	COG4166	transmembrane transport
H1R75_RS06545	COG4166	transmembrane transport
H1R75_RS06550	COG1621	beta-fructofuranosidase activity
H1R75_RS06560	COG1609	Transcriptional regulator
H1R75_RS06565	COG0659	secondary active sulfate transmembrane transporter activity
H1R75_RS06595	COG0456	acetyltransferase
H1R75_RS06630	COG1131	(ABC) transporter
H1R75_RS06685	COG1316	TRANSCRIPTIONal
H1R75_RS06690	COG0077	Prephenate dehydratase
H1R75_RS06695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H1R75_RS06700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1R75_RS06705	COG0481	GTPase activity
H1R75_RS06735	COG0647	UMP catabolic process
H1R75_RS06745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1R75_RS06760	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H1R75_RS06765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1R75_RS06770	COG3442	glutamine amidotransferase
H1R75_RS06780	COG0148	phosphopyruvate hydratase activity
H1R75_RS06795	COG1523	belongs to the glycosyl hydrolase 13 family
H1R75_RS06810	COG0107	imidazoleglycerol-phosphate synthase activity
H1R75_RS06820	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1R75_RS06830	COG0560	Phosphoserine phosphatase
H1R75_RS06835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1R75_RS06845	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H1R75_RS06860	COG0187	DNA topoisomerase II activity
H1R75_RS06870	COG0772	Belongs to the SEDS family
H1R75_RS06885	COG0038	chloride channel
H1R75_RS06890	COG0287	Prephenate dehydrogenase
H1R75_RS06890	COG1605	Chorismate mutase
H1R75_RS06900	COG0716	FMN binding
H1R75_RS06910	COG1454	alcohol dehydrogenase
H1R75_RS06915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H1R75_RS06925	COG0582	viral genome integration into host DNA
H1R75_RS06985	COG1660	Displays ATPase and GTPase activities
H1R75_RS06995	COG1309	transcriptional regulator
H1R75_RS07010	COG0251	oxidation-reduction process
H1R75_RS07030	COG0017	Asparaginyl-tRNA synthetase
H1R75_RS07040	COG0436	Aminotransferase
H1R75_RS07050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1R75_RS07050	COG1199	ATP-dependent helicase activity
H1R75_RS07065	COG2177	Part of the ABC transporter FtsEX involved in
H1R75_RS07070	COG2884	Cell division ATP-binding protein ftsE
H1R75_RS07080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1R75_RS07100	COG1078	dGTPase activity
H1R75_RS07125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H1R75_RS07130	COG0772	Belongs to the SEDS family
H1R75_RS07140	COG1164	Oligoendopeptidase f
H1R75_RS07145	COG0386	Belongs to the glutathione peroxidase family
H1R75_RS07165	COG0406	alpha-ribazole phosphatase activity
H1R75_RS07195	COG1260	myo-inositol-1-phosphate synthase
H1R75_RS07220	COG1309	transcriptional regulator
H1R75_RS07235	COG4443	Transcriptional Coactivator p15 (PC4)
H1R75_RS07285	COG3091	SprT-like family
H1R75_RS07290	COG2183	response to ionizing radiation
H1R75_RS07300	COG0701	Predicted permease
H1R75_RS07305	COG3689	TIGRFAM TIGR03943 family protein
H1R75_RS07315	COG0552	protein localization to endoplasmic reticulum
H1R75_RS07320	COG0561	phosphatase activity
H1R75_RS07325	COG0561	phosphatase activity
H1R75_RS07335	COG1196	nuclear chromosome segregation
H1R75_RS07345	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H1R75_RS07350	COG5002	protein histidine kinase activity
H1R75_RS07355	COG0745	RESPONSE REGULATOR receiver
H1R75_RS07360	COG1126	abc transporter atp-binding protein
H1R75_RS07365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R75_RS07370	COG0765	amino acid transport
H1R75_RS07375	COG0765	amino acid transport
H1R75_RS07390	COG3850	Histidine kinase
H1R75_RS07390	COG5002	protein histidine kinase activity
H1R75_RS07395	COG0745	RESPONSE REGULATOR receiver
H1R75_RS07410	COG4716	Myosin-crossreactive antigen
H1R75_RS07420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H1R75_RS07425	COG0438	transferase activity, transferring glycosyl groups
H1R75_RS07435	COG1609	Transcriptional regulator
H1R75_RS07440	COG0006	proline dipeptidase activity
H1R75_RS07450	COG2816	NAD+ diphosphatase activity
H1R75_RS07460	COG1811	Na channel or pump
H1R75_RS07465	COG1321	iron dependent repressor
H1R75_RS07480	COG0778	Nitroreductase
H1R75_RS07495	COG1846	Transcriptional regulator
H1R75_RS07505	COG0557	exoribonuclease II activity
H1R75_RS07530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H1R75_RS07540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H1R75_RS07545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H1R75_RS07550	COG0366	Alpha amylase catalytic
H1R75_RS07565	COG1702	phosphate starvation-inducible protein PhoH
H1R75_RS07570	COG4479	Belongs to the UPF0346 family
H1R75_RS07580	COG2996	Protein conserved in bacteria
H1R75_RS07610	COG1674	ftsk spoiiie
H1R75_RS07640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H1R75_RS07665	COG1028	Short-chain dehydrogenase reductase Sdr
H1R75_RS07680	COG1695	Transcriptional regulator
H1R75_RS07705	COG0640	Transcriptional regulator
H1R75_RS07710	COG0708	Exodeoxyribonuclease III
H1R75_RS07720	COG1136	(ABC) transporter
H1R75_RS07740	COG1393	Belongs to the ArsC family
H1R75_RS07745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1R75_RS07760	COG0347	Belongs to the P(II) protein family
H1R75_RS07765	COG0004	ammonium transporteR
H1R75_RS07780	COG1774	PSP1 C-terminal conserved region
H1R75_RS07785	COG0470	DNA polymerase III
H1R75_RS07795	COG0516	GMP reductase activity
H1R75_RS07795	COG0517	IMP dehydrogenase activity
H1R75_RS07825	COG4471	UPF0298 protein
H1R75_RS07845	COG0583	DNA-binding transcription factor activity
H1R75_RS07855	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H1R75_RS07860	COG0626	cystathionine gamma-synthase activity
H1R75_RS07865	COG2244	polysaccharide biosynthetic process
H1R75_RS07880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1R75_RS07885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1R75_RS07890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1R75_RS07905	COG3022	response to hydroperoxide
H1R75_RS07925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1R75_RS07930	COG1253	flavin adenine dinucleotide binding
H1R75_RS07935	COG2190	(PTS) system
H1R75_RS07935	COG2211	Major facilitator Superfamily
H1R75_RS07940	COG1119	ATPase activity
H1R75_RS07945	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H1R75_RS07950	COG1242	4 iron, 4 sulfur cluster binding
H1R75_RS07955	COG0671	phosphoesterase, PA-phosphatase related
H1R75_RS07960	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H1R75_RS07970	COG0531	amino acid
H1R75_RS07975	COG0569	domain protein
H1R75_RS07980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1R75_RS07985	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H1R75_RS08005	COG0582	viral genome integration into host DNA
H1R75_RS08025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1R75_RS08030	COG3763	UPF0154 protein
H1R75_RS08050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1R75_RS08055	COG1254	Belongs to the acylphosphatase family
H1R75_RS08070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1R75_RS08100	COG1484	DNA-dependent DNA replication
H1R75_RS08115	COG5002	protein histidine kinase activity
H1R75_RS08120	COG0745	RESPONSE REGULATOR receiver
H1R75_RS08130	COG0501	Belongs to the peptidase M48B family
H1R75_RS08135	COG1704	LemA family
H1R75_RS08150	COG0569	domain protein
H1R75_RS08160	COG1122	ATPase activity
H1R75_RS08170	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H1R75_RS08175	COG1114	Component of the transport system for branched-chain amino acids
H1R75_RS08195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R75_RS08200	COG1473	amidohydrolase
H1R75_RS08205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1R75_RS08210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H1R75_RS08215	COG0217	transcriptional regulatory protein
H1R75_RS08220	COG0789	Transcriptional regulator
H1R75_RS08225	COG1323	Belongs to the UPF0348 family
H1R75_RS08235	COG0640	Transcriptional regulator
H1R75_RS08245	COG2226	methyltransferase
H1R75_RS08250	COG0799	negative regulation of ribosome biogenesis
H1R75_RS08255	COG1335	isochorismatase
H1R75_RS08260	COG1713	HD superfamily hydrolase involved in NAD metabolism
H1R75_RS08265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H1R75_RS08270	COG1534	Rna-binding protein
H1R75_RS08275	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H1R75_RS08280	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H1R75_RS08290	COG0477	Major facilitator Superfamily
H1R75_RS08300	COG0697	spore germination
H1R75_RS08315	COG0154	amidase activity
H1R75_RS08320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1R75_RS08325	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1R75_RS08330	COG0436	Aminotransferase
H1R75_RS08340	COG0589	response to stress
H1R75_RS08345	COG0561	phosphatase activity
H1R75_RS08350	COG0252	asparaginase activity
H1R75_RS08355	COG3655	Transcriptional regulator
H1R75_RS08375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1R75_RS08390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1R75_RS08395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1R75_RS08405	COG1940	carbohydrate kinase activity
H1R75_RS08410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R75_RS08410	COG2190	(PTS) system
H1R75_RS08410	COG1263	PTS System
H1R75_RS08415	COG1621	beta-fructofuranosidase activity
H1R75_RS08420	COG1609	Transcriptional regulator
H1R75_RS08425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H1R75_RS08435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H1R75_RS08445	COG2131	deaminase
H1R75_RS08450	COG0006	proline dipeptidase activity
H1R75_RS08480	COG3655	Transcriptional regulator
H1R75_RS08490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H1R75_RS08525	COG0681	Belongs to the peptidase S26 family
H1R75_RS08535	COG1194	a g-specific adenine glycosylase
H1R75_RS08540	COG3976	FMN-binding domain protein
H1R75_RS08540	COG1053	succinate dehydrogenase
H1R75_RS08540	COG0431	NADPH-dependent FMN reductase
H1R75_RS08570	COG3118	belongs to the thioredoxin family
H1R75_RS08580	COG0157	Belongs to the NadC ModD family
H1R75_RS08590	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1R75_RS08615	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1R75_RS08620	COG0681	Belongs to the peptidase S26 family
H1R75_RS08640	COG1882	Formate acetyltransferase
H1R75_RS08655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1R75_RS08675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H1R75_RS08680	COG0789	Transcriptional regulator
H1R75_RS08695	COG2081	HI0933 family
H1R75_RS08710	COG0456	acetyltransferase
H1R75_RS08715	COG1214	PFAM Peptidase M22, glycoprotease
H1R75_RS08730	COG3942	CHAP domain
H1R75_RS08735	COG0493	'glutamate synthase
H1R75_RS08740	COG0069	glutamate synthase activity
H1R75_RS08740	COG0070	glutamate synthase
H1R75_RS08740	COG0067	glutamate synthase
H1R75_RS08745	COG0174	glutamine synthetase
H1R75_RS08750	COG0789	Transcriptional regulator
H1R75_RS08760	COG0126	phosphoglycerate kinase activity
H1R75_RS08765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1R75_RS08770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H1R75_RS08775	COG0049	tRNA binding
H1R75_RS08785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H1R75_RS08800	COG1564	THIamine pyrophosphokinase
H1R75_RS08805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1R75_RS08830	COG3290	protein histidine kinase activity
H1R75_RS08835	COG3290	protein histidine kinase activity
H1R75_RS08875	COG1266	CAAX protease self-immunity
H1R75_RS08905	COG0084	hydrolase, TatD family'
H1R75_RS08915	COG0281	malic enzyme
H1R75_RS08920	COG0583	DNA-binding transcription factor activity
H1R75_RS08925	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H1R75_RS08930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1R75_RS08935	COG1696	Membrane protein involved in D-alanine export
H1R75_RS08950	COG5002	protein histidine kinase activity
H1R75_RS08955	COG0745	RESPONSE REGULATOR receiver
H1R75_RS08960	COG2207	Transcriptional regulator
H1R75_RS08965	COG2273	Hydrolase Family 16
H1R75_RS08975	COG0395	ABC-type sugar transport system, permease component
H1R75_RS09000	COG2273	Hydrolase Family 16
H1R75_RS09035	COG1131	(ABC) transporter
H1R75_RS09050	COG0594	ribonuclease P activity
H1R75_RS09060	COG0137	argininosuccinate synthase activity
H1R75_RS09065	COG2807	transmembrane transport
H1R75_RS09070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1R75_RS09075	COG4989	oxidoreductase activity
H1R75_RS09090	COG0756	dUTP diphosphatase activity
H1R75_RS09105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1R75_RS09115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1R75_RS09125	COG2171	N-acyltransferase activity
H1R75_RS09130	COG0166	Belongs to the GPI family
H1R75_RS09145	COG1234	tRNA 3'-trailer cleavage
H1R75_RS09150	COG1268	BioY protein
H1R75_RS09160	COG0343	queuine tRNA-ribosyltransferase activity
H1R75_RS09175	COG1832	CoA-binding protein
H1R75_RS09180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1R75_RS09180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1R75_RS09220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1R75_RS09225	COG0542	response to heat
H1R75_RS09230	COG4463	regulation of RNA biosynthetic process
H1R75_RS09240	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H1R75_RS09255	COG1396	sequence-specific DNA binding
H1R75_RS09260	COG3590	peptidase
H1R75_RS09290	COG1309	transcriptional regulator
H1R75_RS09295	COG0602	queuosine metabolic process
H1R75_RS09330	COG4472	Bacterial protein of unknown function (DUF965)
H1R75_RS09335	COG1393	Belongs to the ArsC family
H1R75_RS09345	COG1058	Belongs to the CinA family
H1R75_RS09345	COG1546	Belongs to the CinA family
H1R75_RS09355	COG0519	Catalyzes the synthesis of GMP from XMP
H1R75_RS09390	COG1263	PTS System
H1R75_RS09390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R75_RS09390	COG2190	(PTS) system
H1R75_RS09395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1R75_RS09400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H1R75_RS09420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H1R75_RS09430	COG0366	Alpha amylase catalytic
H1R75_RS09435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1R75_RS09435	COG1263	PTS System
H1R75_RS09440	COG2188	Transcriptional regulator
H1R75_RS09520	COG1674	ftsk spoiiie
H1R75_RS09525	COG4499	WXG100 protein secretion system (Wss), protein YukC
H1R75_RS09540	COG4842	Belongs to the WXG100 family
H1R75_RS09560	COG1511	domain protein
H1R75_RS09560	COG1511	domain protein
H1R75_RS09565	COG1309	transcriptional regulator
H1R75_RS09575	COG4466	Protein conserved in bacteria
H1R75_RS09580	COG0305	Participates in initiation and elongation during chromosome replication
H1R75_RS09595	COG0445	tRNA wobble uridine modification
H1R75_RS09605	COG1760	l-serine dehydratase
H1R75_RS09610	COG1760	l-serine dehydratase
H1R75_RS09615	COG0546	phosphoglycolate phosphatase activity
H1R75_RS09620	COG0741	lytic transglycosylase activity
H1R75_RS09635	COG1122	ATPase activity
H1R75_RS09640	COG1122	ATPase activity
H1R75_RS09645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1R75_RS09655	COG0612	Peptidase, M16
H1R75_RS09660	COG0612	Peptidase, M16
H1R75_RS09670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H1R75_RS09680	COG0516	GMP reductase activity
H1R75_RS09680	COG0517	IMP dehydrogenase activity
H1R75_RS09695	COG0488	(ABC) transporter
H1R75_RS09700	COG4485	Bacterial membrane protein, YfhO
H1R75_RS09725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1R75_RS09730	COG1475	DNA binding