locus-tag	class	description
FOC63_RS00015	COG1175	transmembrane transport
FOC63_RS00020	COG3833	ABC-type maltose transport systems, permease component
FOC63_RS00025	COG2816	NAD+ diphosphatase activity
FOC63_RS00030	COG0556	nucleotide-excision repair
FOC63_RS00035	COG0765	amino acid transport
FOC63_RS00040	COG1126	abc transporter atp-binding protein
FOC63_RS00045	COG0488	(ABC) transporter
FOC63_RS00065	COG1187	pseudouridine synthase activity
FOC63_RS00070	COG4166	transmembrane transport
FOC63_RS00075	COG4166	transmembrane transport
FOC63_RS00090	COG0659	secondary active sulfate transmembrane transporter activity
FOC63_RS00110	COG0590	tRNA wobble adenosine to inosine editing
FOC63_RS00120	COG0456	acetyltransferase
FOC63_RS00165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC63_RS00180	COG1316	TRANSCRIPTIONal
FOC63_RS00185	COG0077	Prephenate dehydratase
FOC63_RS00190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC63_RS00195	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOC63_RS00200	COG0481	GTPase activity
FOC63_RS00230	COG1518	maintenance of DNA repeat elements
FOC63_RS00235	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FOC63_RS00250	COG0647	UMP catabolic process
FOC63_RS00255	COG1051	belongs to the nudix hydrolase family
FOC63_RS00265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC63_RS00270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC63_RS00280	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC63_RS00285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC63_RS00290	COG3442	glutamine amidotransferase
FOC63_RS00295	COG0148	phosphopyruvate hydratase activity
FOC63_RS00315	COG1523	belongs to the glycosyl hydrolase 13 family
FOC63_RS00330	COG0107	imidazoleglycerol-phosphate synthase activity
FOC63_RS00340	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOC63_RS00350	COG0560	Phosphoserine phosphatase
FOC63_RS00355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC63_RS00365	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FOC63_RS00385	COG0187	DNA topoisomerase II activity
FOC63_RS00395	COG0772	Belongs to the SEDS family
FOC63_RS00410	COG0038	chloride channel
FOC63_RS00415	COG0287	Prephenate dehydrogenase
FOC63_RS00415	COG1605	Chorismate mutase
FOC63_RS00430	COG0716	FMN binding
FOC63_RS00440	COG3344	reverse transcriptase
FOC63_RS00450	COG0017	Asparaginyl-tRNA synthetase
FOC63_RS00460	COG0436	Aminotransferase
FOC63_RS00470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC63_RS00470	COG1199	ATP-dependent helicase activity
FOC63_RS00485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOC63_RS00500	COG2177	Part of the ABC transporter FtsEX involved in
FOC63_RS00505	COG2884	Cell division ATP-binding protein ftsE
FOC63_RS00515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC63_RS00540	COG1078	dGTPase activity
FOC63_RS00565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOC63_RS00580	COG0772	Belongs to the SEDS family
FOC63_RS00590	COG1164	Oligoendopeptidase f
FOC63_RS00595	COG0386	Belongs to the glutathione peroxidase family
FOC63_RS00615	COG0588	phosphoglycerate mutase activity
FOC63_RS00645	COG1268	BioY protein
FOC63_RS00650	COG4443	Transcriptional Coactivator p15 (PC4)
FOC63_RS00705	COG2183	response to ionizing radiation
FOC63_RS00715	COG0701	Predicted permease
FOC63_RS00720	COG3689	TIGRFAM TIGR03943 family protein
FOC63_RS00730	COG0789	Transcriptional regulator
FOC63_RS00740	COG0552	protein localization to endoplasmic reticulum
FOC63_RS00745	COG0561	phosphatase activity
FOC63_RS00750	COG0561	phosphatase activity
FOC63_RS00760	COG1196	nuclear chromosome segregation
FOC63_RS00770	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC63_RS00775	COG5002	protein histidine kinase activity
FOC63_RS00780	COG0745	RESPONSE REGULATOR receiver
FOC63_RS00785	COG1126	abc transporter atp-binding protein
FOC63_RS00790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC63_RS00795	COG0765	amino acid transport
FOC63_RS00800	COG0765	amino acid transport
FOC63_RS00820	COG0745	RESPONSE REGULATOR receiver
FOC63_RS00845	COG4716	Myosin-crossreactive antigen
FOC63_RS00920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC63_RS00925	COG0438	transferase activity, transferring glycosyl groups
FOC63_RS00935	COG1609	Transcriptional regulator
FOC63_RS00940	COG0006	proline dipeptidase activity
FOC63_RS00960	COG2190	(PTS) system
FOC63_RS00960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC63_RS00960	COG1263	PTS System
FOC63_RS00980	COG3394	polysaccharide catabolic process
FOC63_RS00990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC63_RS00990	COG1263	PTS System
FOC63_RS00990	COG2190	(PTS) system
FOC63_RS01010	COG0163	prenyltransferase activity
FOC63_RS01015	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOC63_RS01020	COG0583	DNA-binding transcription factor activity
FOC63_RS01025	COG1811	Na channel or pump
FOC63_RS01040	COG0778	Nitroreductase
FOC63_RS01045	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS01050	COG2190	(PTS) system
FOC63_RS01050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC63_RS01050	COG1263	PTS System
FOC63_RS01065	COG0557	exoribonuclease II activity
FOC63_RS01080	COG2814	Major facilitator Superfamily
FOC63_RS01085	COG0237	dephospho-CoA kinase activity
FOC63_RS01090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOC63_RS01100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC63_RS01105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOC63_RS01110	COG0366	Alpha amylase catalytic
FOC63_RS01125	COG1702	phosphate starvation-inducible protein PhoH
FOC63_RS01135	COG4479	Belongs to the UPF0346 family
FOC63_RS01145	COG2996	Protein conserved in bacteria
FOC63_RS01185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC63_RS01195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC63_RS01210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC63_RS01225	COG1028	Short-chain dehydrogenase reductase Sdr
FOC63_RS01240	COG1695	Transcriptional regulator
FOC63_RS01255	COG0534	Mate efflux family protein
FOC63_RS01265	COG0708	Exodeoxyribonuclease III
FOC63_RS01270	COG2814	Major facilitator Superfamily
FOC63_RS01290	COG0656	L-ascorbic acid biosynthetic process
FOC63_RS01300	COG0583	DNA-binding transcription factor activity
FOC63_RS01305	COG1393	Belongs to the ArsC family
FOC63_RS01310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC63_RS01320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC63_RS01345	COG0004	ammonium transporteR
FOC63_RS01360	COG1774	PSP1 C-terminal conserved region
FOC63_RS01365	COG0470	DNA polymerase III
FOC63_RS01375	COG0517	IMP dehydrogenase activity
FOC63_RS01375	COG1227	inorganic diphosphatase activity
FOC63_RS01425	COG0583	DNA-binding transcription factor activity
FOC63_RS01430	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOC63_RS01435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC63_RS01440	COG0626	cystathionine gamma-synthase activity
FOC63_RS01445	COG2244	polysaccharide biosynthetic process
FOC63_RS01450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC63_RS01455	COG1120	ATPase activity
FOC63_RS01460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC63_RS01465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC63_RS01470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC63_RS01485	COG3022	response to hydroperoxide
FOC63_RS01495	COG1227	inorganic diphosphatase activity
FOC63_RS01505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC63_RS01510	COG1253	flavin adenine dinucleotide binding
FOC63_RS01515	COG1119	ATPase activity
FOC63_RS01520	COG0025	NhaP-type Na H and K H
FOC63_RS01530	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC63_RS01535	COG1242	4 iron, 4 sulfur cluster binding
FOC63_RS01540	COG0671	phosphoesterase, PA-phosphatase related
FOC63_RS01550	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC63_RS01560	COG0300	oxidoreductase activity
FOC63_RS01565	COG0789	Transcriptional regulator
FOC63_RS01570	COG0531	amino acid
FOC63_RS01575	COG0569	domain protein
FOC63_RS01580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC63_RS01585	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOC63_RS01590	COG1187	pseudouridine synthase activity
FOC63_RS01605	COG0582	viral genome integration into host DNA
FOC63_RS01625	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC63_RS01630	COG3763	UPF0154 protein
FOC63_RS01650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC63_RS01655	COG1254	Belongs to the acylphosphatase family
FOC63_RS01670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC63_RS01680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC63_RS01690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC63_RS01700	COG1484	DNA-dependent DNA replication
FOC63_RS01715	COG5002	protein histidine kinase activity
FOC63_RS01720	COG0745	RESPONSE REGULATOR receiver
FOC63_RS01770	COG0791	NLP P60 protein
FOC63_RS01770	COG0741	lytic transglycosylase activity
FOC63_RS01800	COG2946	Replication initiation factor
FOC63_RS01810	COG1674	ftsk spoiiie
FOC63_RS01830	COG0501	Belongs to the peptidase M48B family
FOC63_RS01835	COG1704	LemA family
FOC63_RS01845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC63_RS01850	COG0569	domain protein
FOC63_RS01860	COG1122	ATPase activity
FOC63_RS01880	COG1114	Component of the transport system for branched-chain amino acids
FOC63_RS01895	COG2910	NAD(P)H-binding
FOC63_RS01900	COG1959	2 iron, 2 sulfur cluster binding
FOC63_RS01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC63_RS01930	COG1473	amidohydrolase
FOC63_RS01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC63_RS01940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOC63_RS01945	COG0217	transcriptional regulatory protein
FOC63_RS01950	COG2190	(PTS) system
FOC63_RS01950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC63_RS01950	COG1263	PTS System
FOC63_RS01955	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS01960	COG1737	Transcriptional regulator
FOC63_RS01965	COG0702	epimerase
FOC63_RS01970	COG0789	Transcriptional regulator
FOC63_RS01975	COG1323	Belongs to the UPF0348 family
FOC63_RS01980	COG2226	methyltransferase
FOC63_RS01985	COG0799	negative regulation of ribosome biogenesis
FOC63_RS01990	COG1335	isochorismatase
FOC63_RS01995	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC63_RS02000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOC63_RS02005	COG1534	Rna-binding protein
FOC63_RS02010	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC63_RS02020	COG2814	Major facilitator Superfamily
FOC63_RS02025	COG1846	Transcriptional regulator
FOC63_RS02040	COG0154	amidase activity
FOC63_RS02045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOC63_RS02050	COG1335	isochorismatase
FOC63_RS02055	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FOC63_RS02060	COG0436	Aminotransferase
FOC63_RS02070	COG0589	response to stress
FOC63_RS02075	COG0561	phosphatase activity
FOC63_RS02080	COG0252	asparaginase activity
FOC63_RS02085	COG3655	Transcriptional regulator
FOC63_RS02100	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC63_RS02115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC63_RS02120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC63_RS02130	COG1940	carbohydrate kinase activity
FOC63_RS02135	COG2190	(PTS) system
FOC63_RS02135	COG1263	PTS System
FOC63_RS02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC63_RS02140	COG1621	beta-fructofuranosidase activity
FOC63_RS02145	COG1609	Transcriptional regulator
FOC63_RS02150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC63_RS02160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOC63_RS02175	COG2131	deaminase
FOC63_RS02180	COG0006	proline dipeptidase activity
FOC63_RS02200	COG0598	Magnesium transport protein CorA
FOC63_RS02215	COG3655	Transcriptional regulator
FOC63_RS02225	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOC63_RS02230	COG0629	single-stranded DNA binding
FOC63_RS02250	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOC63_RS02260	COG3634	alkyl hydroperoxide reductase activity
FOC63_RS02265	COG0450	alkyl hydroperoxide reductase
FOC63_RS02270	COG1116	anion transmembrane transporter activity
FOC63_RS02275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC63_RS02285	COG0318	PFAM AMP-dependent synthetase and ligase
FOC63_RS02300	COG1194	a g-specific adenine glycosylase
FOC63_RS02310	COG2223	nitrite transmembrane transporter activity
FOC63_RS02365	COG1063	alcohol dehydrogenase
FOC63_RS02370	COG3118	belongs to the thioredoxin family
FOC63_RS02380	COG0157	Belongs to the NadC ModD family
FOC63_RS02390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOC63_RS02405	COG3842	ATPase activity
FOC63_RS02425	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOC63_RS02430	COG0681	Belongs to the peptidase S26 family
FOC63_RS02435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC63_RS02450	COG1882	Formate acetyltransferase
FOC63_RS02465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC63_RS02485	COG5002	protein histidine kinase activity
FOC63_RS02500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC63_RS02505	COG0581	inorganic phosphate transmembrane transporter activity
FOC63_RS02510	COG0573	inorganic phosphate transmembrane transporter activity
FOC63_RS02530	COG0789	Transcriptional regulator
FOC63_RS02545	COG2081	HI0933 family
FOC63_RS02575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOC63_RS02585	COG0456	acetyltransferase
FOC63_RS02590	COG1214	PFAM Peptidase M22, glycoprotease
FOC63_RS02605	COG3942	CHAP domain
FOC63_RS02610	COG0493	'glutamate synthase
FOC63_RS02615	COG0067	glutamate synthase
FOC63_RS02615	COG0070	glutamate synthase
FOC63_RS02615	COG0069	glutamate synthase activity
FOC63_RS02620	COG0174	glutamine synthetase
FOC63_RS02625	COG0789	Transcriptional regulator
FOC63_RS02635	COG0126	phosphoglycerate kinase activity
FOC63_RS02645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC63_RS02660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC63_RS02680	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC63_RS02705	COG3290	protein histidine kinase activity
FOC63_RS02785	COG2274	protein secretion by the type I secretion system
FOC63_RS02790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC63_RS02795	COG1266	CAAX protease self-immunity
FOC63_RS02820	COG0084	hydrolase, TatD family'
FOC63_RS02840	COG2217	Heavy metal translocating P-type atpase
FOC63_RS02865	COG0681	Belongs to the peptidase S26 family
FOC63_RS02875	COG2226	methyltransferase
FOC63_RS02880	COG1132	(ABC) transporter
FOC63_RS02905	COG0281	malic enzyme
FOC63_RS02910	COG0583	DNA-binding transcription factor activity
FOC63_RS02920	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC63_RS02925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC63_RS02930	COG1696	Membrane protein involved in D-alanine export
FOC63_RS02955	COG1394	ATPase activity, coupled to movement of substances
FOC63_RS02960	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FOC63_RS02970	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
FOC63_RS02975	COG1527	subunit (C
FOC63_RS02985	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC63_RS02990	COG1269	ATP hydrolysis coupled proton transport
FOC63_RS03025	COG1131	(ABC) transporter
FOC63_RS03040	COG0594	ribonuclease P activity
FOC63_RS03055	COG2211	Major facilitator Superfamily
FOC63_RS03085	COG2205	protein histidine kinase activity
FOC63_RS03090	COG2807	transmembrane transport
FOC63_RS03095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC63_RS03120	COG0756	dUTP diphosphatase activity
FOC63_RS03140	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOC63_RS03145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC63_RS03150	COG0705	Rhomboid family
FOC63_RS03150	COG0457	Tetratricopeptide repeat
FOC63_RS03155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC63_RS03165	COG2171	N-acyltransferase activity
FOC63_RS03175	COG0166	Belongs to the GPI family
FOC63_RS03195	COG1234	tRNA 3'-trailer cleavage
FOC63_RS03200	COG1268	BioY protein
FOC63_RS03210	COG0343	queuine tRNA-ribosyltransferase activity
FOC63_RS03225	COG3479	Phenolic acid decarboxylase
FOC63_RS03230	COG1695	Transcriptional regulator
FOC63_RS03235	COG1832	CoA-binding protein
FOC63_RS03240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC63_RS03240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC63_RS03255	COG0697	spore germination
FOC63_RS03270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC63_RS03270	COG0473	3-isopropylmalate dehydrogenase activity
FOC63_RS03275	COG0473	3-isopropylmalate dehydrogenase activity
FOC63_RS03275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC63_RS03285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC63_RS03290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOC63_RS03315	COG3623	hexulose-6-phosphate isomerase
FOC63_RS03325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC63_RS03335	COG3037	sugar-specific permease SgaT UlaA
FOC63_RS03345	COG1979	alcohol dehydrogenase
FOC63_RS03350	COG1464	Belongs to the NlpA lipoprotein family
FOC63_RS03355	COG2011	ABC-type metal ion transport system permease component
FOC63_RS03360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC63_RS03370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOC63_RS03375	COG2918	glutathione biosynthetic process
FOC63_RS03375	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOC63_RS03405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC63_RS03435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOC63_RS03440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC63_RS03445	COG0542	response to heat
FOC63_RS03450	COG4463	regulation of RNA biosynthetic process
FOC63_RS03470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOC63_RS03485	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC63_RS03490	COG1396	sequence-specific DNA binding
FOC63_RS03495	COG3590	peptidase
FOC63_RS03505	COG0366	Alpha amylase catalytic
FOC63_RS03510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC63_RS03510	COG1263	PTS System
FOC63_RS03515	COG2188	Transcriptional regulator
FOC63_RS03540	COG2255	four-way junction helicase activity
FOC63_RS03545	COG0602	queuosine metabolic process
FOC63_RS03580	COG4472	Bacterial protein of unknown function (DUF965)
FOC63_RS03585	COG1393	Belongs to the ArsC family
FOC63_RS03595	COG1058	Belongs to the CinA family
FOC63_RS03595	COG1546	Belongs to the CinA family
FOC63_RS03665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC63_RS03670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC63_RS03695	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC63_RS03730	COG3759	membrane
FOC63_RS03735	COG1511	domain protein
FOC63_RS03750	COG4466	Protein conserved in bacteria
FOC63_RS03755	COG0305	Participates in initiation and elongation during chromosome replication
FOC63_RS03770	COG0445	tRNA wobble uridine modification
FOC63_RS03780	COG0482	sulfurtransferase activity
FOC63_RS03785	COG1760	l-serine dehydratase
FOC63_RS03790	COG1760	l-serine dehydratase
FOC63_RS03795	COG0546	phosphoglycolate phosphatase activity
FOC63_RS03800	COG0741	lytic transglycosylase activity
FOC63_RS03815	COG1122	ATPase activity
FOC63_RS03820	COG1122	ATPase activity
FOC63_RS03825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC63_RS03835	COG0612	Peptidase, M16
FOC63_RS03840	COG0612	Peptidase, M16
FOC63_RS03850	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC63_RS03860	COG0516	GMP reductase activity
FOC63_RS03860	COG0517	IMP dehydrogenase activity
FOC63_RS03870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC63_RS03875	COG0488	(ABC) transporter
FOC63_RS03905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC63_RS03910	COG1475	DNA binding
FOC63_RS03920	COG0592	DNA-directed DNA polymerase activity
FOC63_RS03935	COG0012	GTP binding
FOC63_RS03945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC63_RS03955	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC63_RS03985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC63_RS04160	COG1792	Involved in formation and maintenance of cell shape
FOC63_RS04170	COG3942	CHAP domain
FOC63_RS04180	COG0436	Aminotransferase
FOC63_RS04190	COG0416	fatty acid biosynthetic process
FOC63_RS04195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC63_RS04200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOC63_RS04205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC63_RS04215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOC63_RS04220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC63_RS04235	COG0151	Belongs to the GarS family
FOC63_RS04240	COG1683	Conserved Protein
FOC63_RS04245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC63_RS04260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC63_RS04270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC63_RS04295	COG2409	Drug exporters of the RND superfamily
FOC63_RS04305	COG2197	response regulator
FOC63_RS04310	COG0583	DNA-binding transcription factor activity
FOC63_RS04320	COG0051	transcription antitermination factor activity, RNA binding
FOC63_RS04330	COG0088	Forms part of the polypeptide exit tunnel
FOC63_RS04335	COG0089	rRNA binding
FOC63_RS04365	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC63_RS04380	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOC63_RS04390	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOC63_RS04410	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOC63_RS04415	COG1841	ribosomal large subunit assembly
FOC63_RS04425	COG0201	protein transport
FOC63_RS04430	COG0563	adenylate kinase activity
FOC63_RS04445	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOC63_RS04450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOC63_RS04455	COG0202	RNA polymerase activity
FOC63_RS04460	COG0203	ribosomal protein L17
FOC63_RS04545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOC63_RS04555	COG1121	(ABC) transporter
FOC63_RS04560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC63_RS04590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC63_RS04595	COG1459	type II secretion system
FOC63_RS04600	COG4537	Required for transformation and DNA binding
FOC63_RS04650	COG1266	CAAX protease self-immunity
FOC63_RS04655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC63_RS04660	COG1363	Peptidase, m42
FOC63_RS04675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC63_RS04680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC63_RS04695	COG2391	methyltransferase activity
FOC63_RS04700	COG0425	Belongs to the sulfur carrier protein TusA family
FOC63_RS04705	COG0561	phosphatase activity
FOC63_RS04710	COG1621	beta-fructofuranosidase activity
FOC63_RS04710	COG3583	domain protein
FOC63_RS04710	COG5492	domain, Protein
FOC63_RS04720	COG4585	Histidine kinase
FOC63_RS04725	COG2197	response regulator
FOC63_RS04745	COG3715	PTS system
FOC63_RS04750	COG3716	PTS system mannose fructose sorbose family IID component
FOC63_RS04760	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOC63_RS04765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC63_RS04780	COG1396	sequence-specific DNA binding
FOC63_RS04790	COG0564	pseudouridine synthase activity
FOC63_RS04800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC63_RS04825	COG4667	esterase of the alpha-beta hydrolase superfamily
FOC63_RS04835	COG2017	converts alpha-aldose to the beta-anomer
FOC63_RS04845	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC63_RS04865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC63_RS04890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC63_RS04895	COG1609	Transcriptional regulator
FOC63_RS04900	COG1263	PTS System
FOC63_RS04900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC63_RS04900	COG2190	(PTS) system
FOC63_RS04915	COG1363	Peptidase, m42
FOC63_RS04925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC63_RS04930	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC63_RS04935	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS04940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC63_RS04945	COG2188	Transcriptional regulator
FOC63_RS04950	COG1482	cell wall glycoprotein biosynthetic process
FOC63_RS04960	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOC63_RS04965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOC63_RS04975	COG1653	transport
FOC63_RS04980	COG1175	transmembrane transport
FOC63_RS04985	COG0395	ABC-type sugar transport system, permease component
FOC63_RS05000	COG2188	Transcriptional regulator
FOC63_RS05005	COG1940	carbohydrate kinase activity
FOC63_RS05035	COG3842	ATPase activity
FOC63_RS05075	COG3775	system Galactitol-specific IIC component
FOC63_RS05085	COG3711	transcriptional antiterminator
FOC63_RS05090	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS05095	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC63_RS05100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC63_RS05100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC63_RS05105	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FOC63_RS05110	COG2207	Transcriptional regulator
FOC63_RS05115	COG3345	alpha-galactosidase
FOC63_RS05120	COG1653	transport
FOC63_RS05125	COG1175	transmembrane transport
FOC63_RS05130	COG0395	ABC-type sugar transport system, permease component
FOC63_RS05135	COG0366	Alpha amylase catalytic
FOC63_RS05140	COG0366	Alpha amylase catalytic
FOC63_RS05145	COG1609	Transcriptional regulator
FOC63_RS05150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOC63_RS05155	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FOC63_RS05160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC63_RS05170	COG1862	Preprotein translocase
FOC63_RS05175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC63_RS05180	COG4589	Belongs to the CDS family
FOC63_RS05215	COG0242	peptide deformylase activity
FOC63_RS05235	COG0346	lactoylglutathione lyase activity
FOC63_RS05240	COG0561	phosphatase activity
FOC63_RS05250	COG1454	alcohol dehydrogenase
FOC63_RS05250	COG1012	belongs to the aldehyde dehydrogenase family
FOC63_RS05265	COG1185	polyribonucleotide nucleotidyltransferase activity
FOC63_RS05275	COG1045	serine acetyltransferase
FOC63_RS05285	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FOC63_RS05315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOC63_RS05355	COG3830	Belongs to the UPF0237 family
FOC63_RS05360	COG2848	UPF0210 protein
FOC63_RS05365	COG0588	phosphoglycerate mutase activity
FOC63_RS05375	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOC63_RS05390	COG0443	Heat shock 70 kDa protein
FOC63_RS05410	COG0351	phosphomethylpyrimidine kinase
FOC63_RS05410	COG0352	thiamine-phosphate diphosphorylase activity
FOC63_RS05425	COG0668	transmembrane transport
FOC63_RS05440	COG0504	CTP synthase activity
FOC63_RS05465	COG0191	fructose-bisphosphate aldolase activity
FOC63_RS05475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOC63_RS05485	COG1461	Dihydroxyacetone kinase
FOC63_RS05490	COG0129	dihydroxy-acid dehydratase activity
FOC63_RS05495	COG0028	Belongs to the TPP enzyme family
FOC63_RS05500	COG0440	acetolactate synthase activity
FOC63_RS05505	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC63_RS05510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC63_RS05530	COG1126	abc transporter atp-binding protein
FOC63_RS05535	COG0765	amino acid transport
FOC63_RS05555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC63_RS05565	COG0719	Fe-S assembly protein
FOC63_RS05570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC63_RS05580	COG0719	Fe-S assembly protein
FOC63_RS05585	COG1686	Belongs to the peptidase S11 family
FOC63_RS05590	COG4166	transmembrane transport
FOC63_RS05595	COG0601	transmembrane transport
FOC63_RS05600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC63_RS05605	COG0444	Belongs to the ABC transporter superfamily
FOC63_RS05610	COG4608	Belongs to the ABC transporter superfamily
FOC63_RS05645	COG2755	lipolytic protein G-D-S-L family
FOC63_RS05645	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FOC63_RS05650	COG0527	aspartate kinase activity
FOC63_RS05655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC63_RS05660	COG1024	Enoyl-CoA hydratase
FOC63_RS05670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC63_RS05680	COG2070	2-Nitropropane dioxygenase
FOC63_RS05685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC63_RS05690	COG1028	Short-chain dehydrogenase reductase Sdr
FOC63_RS05695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC63_RS05710	COG0439	Biotin carboxylase
FOC63_RS05725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOC63_RS05735	COG3716	PTS system mannose fructose sorbose family IID component
FOC63_RS05740	COG3715	PTS system
FOC63_RS05750	COG0561	phosphatase activity
FOC63_RS05765	COG2252	PERMEase
FOC63_RS05770	COG0802	atpase or kinase
FOC63_RS05780	COG1316	TRANSCRIPTIONal
FOC63_RS05790	COG0537	adenosine 5'-monophosphoramidase activity
FOC63_RS05795	COG1131	(ABC) transporter
FOC63_RS05800	COG4473	ABC transporter
FOC63_RS05810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOC63_RS05820	COG3300	MHYT domain
FOC63_RS05820	COG5001	Diguanylate cyclase
FOC63_RS05825	COG0463	Glycosyl transferase, family 2
FOC63_RS05845	COG0195	Participates in both transcription termination and antitermination
FOC63_RS05850	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC63_RS05860	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOC63_RS05865	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOC63_RS05890	COG2217	Heavy metal translocating P-type atpase
FOC63_RS05900	COG2860	membrane
FOC63_RS05905	COG0561	phosphatase activity
FOC63_RS05940	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC63_RS05965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC63_RS05965	COG3711	transcriptional antiterminator
FOC63_RS05975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC63_RS05975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC63_RS05975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC63_RS05980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC63_RS05990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC63_RS06010	COG1131	(ABC) transporter
FOC63_RS06020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC63_RS06020	COG2190	(PTS) system
FOC63_RS06020	COG1263	PTS System
FOC63_RS06025	COG1737	Transcriptional regulator
FOC63_RS06030	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS06035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC63_RS06040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOC63_RS06055	COG0768	penicillin binding
FOC63_RS06060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC63_RS06065	COG0513	Belongs to the DEAD box helicase family
FOC63_RS06080	COG1126	abc transporter atp-binding protein
FOC63_RS06105	COG2314	TM2 domain
FOC63_RS06170	COG3935	DnaD domain protein
FOC63_RS06200	COG0629	single-stranded DNA binding
FOC63_RS06370	COG1388	LysM domain
FOC63_RS06370	COG3942	CHAP domain
FOC63_RS06385	COG2095	MarC family integral membrane protein
FOC63_RS06390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC63_RS06395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOC63_RS06400	COG3579	cysteine-type endopeptidase activity
FOC63_RS06405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC63_RS06410	COG3331	DNA recombination
FOC63_RS06420	COG3599	regulation of cell shape
FOC63_RS06430	COG0116	Belongs to the methyltransferase superfamily
FOC63_RS06445	COG1854	S-ribosylhomocysteine lyase activity
FOC63_RS06465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC63_RS06475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC63_RS06475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC63_RS06495	COG4585	Histidine kinase
FOC63_RS06500	COG2197	response regulator
FOC63_RS06510	COG1098	S1 RNA binding domain
FOC63_RS06520	COG1739	Uncharacterized protein family UPF0029
FOC63_RS06525	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC63_RS06530	COG1040	competence protein
FOC63_RS06600	COG3557	Belongs to the UPF0374 family
FOC63_RS06605	COG2137	regulation of response to DNA damage stimulus
FOC63_RS06615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC63_RS06635	COG1428	Deoxynucleoside kinase
FOC63_RS06660	COG0519	Catalyzes the synthesis of GMP from XMP
FOC63_RS06670	COG0525	valine-tRNA ligase activity
FOC63_RS06675	COG1396	sequence-specific DNA binding
FOC63_RS06695	COG1309	transcriptional regulator
FOC63_RS06720	COG0742	ribosomal rna small subunit methyltransferase
FOC63_RS06725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOC63_RS06730	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC63_RS06740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC63_RS06750	COG0737	Belongs to the 5'-nucleotidase family
FOC63_RS06755	COG4470	Protein conserved in bacteria
FOC63_RS06770	COG1132	(ABC) transporter
FOC63_RS06775	COG1132	(ABC) transporter
FOC63_RS06780	COG1131	(ABC) transporter
FOC63_RS06790	COG4585	Histidine kinase
FOC63_RS06795	COG2197	response regulator
FOC63_RS07005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC63_RS07010	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC63_RS07020	COG0134	indole-3-glycerol-phosphate synthase activity
FOC63_RS07025	COG0135	phosphoribosylanthranilate isomerase activity
FOC63_RS07030	COG0133	tryptophan synthase activity
FOC63_RS07035	COG0159	tryptophan synthase activity
FOC63_RS07040	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC63_RS07050	COG0783	Belongs to the Dps family
FOC63_RS07060	COG1120	ATPase activity
FOC63_RS07100	COG1940	carbohydrate kinase activity
FOC63_RS07105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC63_RS07125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC63_RS07130	COG2207	Transcriptional regulator
FOC63_RS07170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC63_RS07175	COG1799	cell septum assembly
FOC63_RS07190	COG3599	regulation of cell shape
FOC63_RS07210	COG0542	response to heat
FOC63_RS07225	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOC63_RS07230	COG4703	Protein of unknown function (DUF1797)
FOC63_RS07235	COG0765	amino acid transport
FOC63_RS07240	COG1126	abc transporter atp-binding protein
FOC63_RS07265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOC63_RS07280	COG1376	ErfK ybiS ycfS ynhG family protein
FOC63_RS07300	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC63_RS07305	COG1438	arginine binding
FOC63_RS07310	COG0497	DNA recombination
FOC63_RS07315	COG1307	EDD domain protein, DegV family
FOC63_RS07320	COG2755	lipolytic protein G-D-S-L family
FOC63_RS07325	COG4698	Protein conserved in bacteria
FOC63_RS07340	COG3104	oligopeptide transport
FOC63_RS07345	COG0167	dihydroorotate dehydrogenase activity
FOC63_RS07350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC63_RS07350	COG3321	synthase
FOC63_RS07350	COG4221	oxidoreductase activity
FOC63_RS07350	COG0604	alcohol dehydrogenase
FOC63_RS07355	COG0640	Transcriptional regulator
FOC63_RS07360	COG2217	Heavy metal translocating P-type atpase
FOC63_RS07365	COG2076	Multidrug Resistance protein
FOC63_RS07475	COG1827	regulation of RNA biosynthetic process
FOC63_RS07485	COG0768	penicillin binding
FOC63_RS07490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOC63_RS07495	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOC63_RS07505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC63_RS07520	COG0513	Belongs to the DEAD box helicase family
FOC63_RS07530	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC63_RS07535	COG0204	Acyl-transferase
FOC63_RS07540	COG1555	photosystem II stabilization
FOC63_RS07540	COG1596	polysaccharide export
FOC63_RS07545	COG0658	competence protein
FOC63_RS07545	COG2333	competence protein COMEC
FOC63_RS07550	COG1466	dna polymerase III delta subunit
FOC63_RS07555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC63_RS07560	COG0217	transcriptional regulatory protein
FOC63_RS07575	COG0363	glucosamine-6-phosphate deaminase activity
FOC63_RS07580	COG1187	pseudouridine synthase activity
FOC63_RS07600	COG0546	phosphoglycolate phosphatase activity
FOC63_RS07605	COG4122	O-methyltransferase activity
FOC63_RS07615	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC63_RS07630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC63_RS07635	COG0436	Aminotransferase
FOC63_RS07655	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC63_RS07660	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOC63_RS07665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC63_RS07670	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC63_RS07675	COG0583	DNA-binding transcription factor activity
FOC63_RS07680	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC63_RS07690	COG0656	L-ascorbic acid biosynthetic process
FOC63_RS07695	COG1902	pentaerythritol trinitrate reductase activity
FOC63_RS07705	COG0789	Transcriptional regulator
FOC63_RS07715	COG1476	TRANSCRIPTIONal
FOC63_RS07725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC63_RS07725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC63_RS07730	COG0307	riboflavin synthase, alpha
FOC63_RS07735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC63_RS07735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC63_RS07755	COG0656	L-ascorbic acid biosynthetic process
FOC63_RS07760	COG0656	L-ascorbic acid biosynthetic process
FOC63_RS07775	COG3859	Proton-coupled thiamine transporter YuaJ
FOC63_RS07780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC63_RS07785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC63_RS07790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC63_RS07795	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC63_RS07800	COG0372	Belongs to the citrate synthase family
FOC63_RS07820	COG1609	Transcriptional regulator
FOC63_RS07825	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC63_RS07830	COG0251	oxidation-reduction process
FOC63_RS07840	COG1309	transcriptional regulator
FOC63_RS07920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC63_RS07925	COG1660	Displays ATPase and GTPase activities
FOC63_RS07945	COG1396	sequence-specific DNA binding
FOC63_RS07970	COG2226	methyltransferase
FOC63_RS07985	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOC63_RS07985	COG1388	LysM domain
FOC63_RS08030	COG0582	viral genome integration into host DNA
FOC63_RS08040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC63_RS08065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FOC63_RS08075	COG0513	Belongs to the DEAD box helicase family
FOC63_RS08100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC63_RS08105	COG0066	3-isopropylmalate dehydratase activity
FOC63_RS08110	COG1956	GAF domain-containing protein
FOC63_RS08115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC63_RS08130	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOC63_RS08130	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOC63_RS08135	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOC63_RS08150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC63_RS08160	COG4109	DRTGG domain
FOC63_RS08165	COG0024	Methionine aminopeptidase
FOC63_RS08175	COG2246	polysaccharide biosynthetic process
FOC63_RS08180	COG4708	membrane
FOC63_RS08185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC63_RS08190	COG1597	lipid kinase activity
FOC63_RS08195	COG1523	belongs to the glycosyl hydrolase 13 family
FOC63_RS08200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOC63_RS08205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC63_RS08210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC63_RS08215	COG0297	glycogen (starch) synthase activity
FOC63_RS08220	COG0058	SHG alpha-glucan phosphorylase activity
FOC63_RS08230	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC63_RS08235	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOC63_RS08270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC63_RS08285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOC63_RS08290	COG0456	acetyltransferase
FOC63_RS08300	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOC63_RS08305	COG1074	ATP-dependent DNA helicase activity
FOC63_RS08340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC63_RS08355	COG0300	oxidoreductase activity
FOC63_RS08360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC63_RS08360	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC63_RS08385	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC63_RS08425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC63_RS08430	COG2384	SAM-dependent methyltransferase
FOC63_RS08440	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC63_RS08450	COG1088	dTDP-glucose 4,6-dehydratase activity
FOC63_RS08460	COG1051	belongs to the nudix hydrolase family
FOC63_RS08465	COG0628	permease
FOC63_RS08470	COG0457	Tetratricopeptide repeat
FOC63_RS08480	COG0640	Transcriptional regulator
FOC63_RS08485	COG1902	pentaerythritol trinitrate reductase activity
FOC63_RS08490	COG0028	Belongs to the TPP enzyme family
FOC63_RS08495	COG3527	Alpha-acetolactate decarboxylase
FOC63_RS08500	COG0531	amino acid
FOC63_RS08505	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FOC63_RS08510	COG0583	DNA-binding transcription factor activity
FOC63_RS08515	COG1126	abc transporter atp-binding protein
FOC63_RS08530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC63_RS08535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC63_RS08540	COG4187	Peptidase family M20/M25/M40
FOC63_RS08550	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOC63_RS08555	COG3842	ATPase activity
FOC63_RS08600	COG0488	(ABC) transporter
FOC63_RS08610	COG1132	(ABC) transporter
FOC63_RS08615	COG1132	(ABC) transporter
FOC63_RS08625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC63_RS08630	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC63_RS08630	COG0022	dehydrogenase e1 component
FOC63_RS08645	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC63_RS08650	COG4605	iron ion homeostasis
FOC63_RS08655	COG4604	ABC transporter, ATP-binding protein
FOC63_RS08665	COG0697	spore germination
FOC63_RS08670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC63_RS08675	COG0095	Lipoate-protein ligase
FOC63_RS08690	COG0583	DNA-binding transcription factor activity
FOC63_RS08700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC63_RS08730	COG2814	Major facilitator Superfamily
FOC63_RS08745	COG0477	Major facilitator Superfamily
FOC63_RS08750	COG3976	FMN-binding domain protein
FOC63_RS08750	COG1053	succinate dehydrogenase
FOC63_RS08750	COG0431	NADPH-dependent FMN reductase
FOC63_RS08760	COG3976	FMN-binding domain protein
FOC63_RS08760	COG1053	succinate dehydrogenase
FOC63_RS08760	COG0431	NADPH-dependent FMN reductase
FOC63_RS08765	COG3976	FMN-binding domain protein
FOC63_RS08765	COG1053	succinate dehydrogenase
FOC63_RS08765	COG0431	NADPH-dependent FMN reductase
FOC63_RS08775	COG1937	Protein conserved in bacteria
FOC63_RS08785	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC63_RS08795	COG1418	mRNA catabolic process
FOC63_RS08815	COG0583	DNA-binding transcription factor activity
FOC63_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
FOC63_RS08830	COG1979	alcohol dehydrogenase
FOC63_RS08845	COG0789	Transcriptional regulator
FOC63_RS08850	COG0656	L-ascorbic acid biosynthetic process
FOC63_RS08875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC63_RS08880	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS08885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC63_RS08890	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC63_RS08895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC63_RS08895	COG3711	transcriptional antiterminator
FOC63_RS08900	COG1011	Hydrolase
FOC63_RS08910	COG0583	DNA-binding transcription factor activity
FOC63_RS08915	COG2855	membrane
FOC63_RS08920	COG1012	belongs to the aldehyde dehydrogenase family
FOC63_RS08930	COG0322	excinuclease ABC activity
FOC63_RS08955	COG1573	uracil-dna glycosylase
FOC63_RS08980	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOC63_RS08985	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOC63_RS09015	COG1316	TRANSCRIPTIONal
FOC63_RS09035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC63_RS09045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOC63_RS09050	COG3475	LICD family
FOC63_RS09065	COG1442	glycosyl transferase family 8
FOC63_RS09065	COG1216	Glycosyl transferase, family 2
FOC63_RS09100	COG0167	dihydroorotate dehydrogenase activity
FOC63_RS09105	COG0284	orotidine-5'-phosphate decarboxylase activity
FOC63_RS09110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOC63_RS09120	COG1881	PFAM PEBP family protein
FOC63_RS09140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC63_RS09145	COG0187	DNA topoisomerase II activity
FOC63_RS09150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC63_RS09155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC63_RS09175	COG0539	negative regulation of cytoplasmic translation
FOC63_RS09185	COG1346	cytolysis
FOC63_RS09190	COG1380	Effector of murein hydrolase LrgA
FOC63_RS09210	COG1131	(ABC) transporter
FOC63_RS09215	COG1725	Transcriptional regulator
FOC63_RS09225	COG0205	6-phosphofructokinase activity
FOC63_RS09230	COG0469	pyruvate kinase activity
FOC63_RS09245	COG2213	PTS system mannitol-specific
FOC63_RS09250	COG3711	transcriptional antiterminator
FOC63_RS09255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC63_RS09260	COG0246	Mannitol dehydrogenase
FOC63_RS09265	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC63_RS09270	COG0765	amino acid transport
FOC63_RS09275	COG1126	abc transporter atp-binding protein
FOC63_RS09280	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOC63_RS09285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC63_RS09290	COG1115	amino acid carrier protein
FOC63_RS09295	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS09305	COG0406	alpha-ribazole phosphatase activity
FOC63_RS09315	COG0628	permease
FOC63_RS09320	COG1442	glycosyl transferase family 8
FOC63_RS09330	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FOC63_RS09340	COG1104	cysteine desulfurase activity
FOC63_RS09355	COG2357	RelA SpoT domain protein
FOC63_RS09365	COG0564	pseudouridine synthase activity
FOC63_RS09370	COG0280	phosphate acetyltransferase
FOC63_RS09375	COG4221	oxidoreductase activity
FOC63_RS09385	COG0561	phosphatase activity
FOC63_RS09390	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS09395	COG1136	(ABC) transporter
FOC63_RS09400	COG0577	efflux transmembrane transporter activity
FOC63_RS09405	COG0516	GMP reductase activity
FOC63_RS09410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC63_RS09430	COG2233	PERMEase
FOC63_RS09460	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC63_RS09465	COG0009	L-threonylcarbamoyladenylate synthase
FOC63_RS09485	COG1132	(ABC) transporter
FOC63_RS09490	COG1132	(ABC) transporter
FOC63_RS09510	COG3711	transcriptional antiterminator
FOC63_RS09525	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS09530	COG0519	Catalyzes the synthesis of GMP from XMP
FOC63_RS09530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC63_RS09555	COG1819	glycosyl
FOC63_RS09560	COG1396	sequence-specific DNA binding
FOC63_RS09570	COG1396	sequence-specific DNA binding
FOC63_RS09575	COG5263	repeat protein
FOC63_RS09575	COG0366	Alpha amylase catalytic
FOC63_RS09585	COG0534	Mate efflux family protein
FOC63_RS09605	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC63_RS09610	COG0210	DNA helicase
FOC63_RS09615	COG2188	Transcriptional regulator
FOC63_RS09645	COG1737	Transcriptional regulator
FOC63_RS09650	COG0673	inositol 2-dehydrogenase activity
FOC63_RS09660	COG0673	inositol 2-dehydrogenase activity
FOC63_RS09665	COG4115	mRNA cleavage
FOC63_RS09675	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FOC63_RS09680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC63_RS09690	COG1132	(ABC) transporter
FOC63_RS09695	COG1132	(ABC) transporter
FOC63_RS09720	COG4974	Belongs to the 'phage' integrase family
FOC63_RS09730	COG5002	protein histidine kinase activity
FOC63_RS09735	COG0745	RESPONSE REGULATOR receiver
FOC63_RS09740	COG0577	efflux transmembrane transporter activity
FOC63_RS09745	COG1136	(ABC) transporter
FOC63_RS09750	COG3344	reverse transcriptase
FOC63_RS09760	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FOC63_RS09780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC63_RS09790	COG0110	maltose O-acetyltransferase activity
FOC63_RS09795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOC63_RS09800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC63_RS09845	COG1131	(ABC) transporter
FOC63_RS09850	COG0488	(ABC) transporter
FOC63_RS09865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC63_RS09870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC63_RS09875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC63_RS09880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC63_RS09915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC63_RS09920	COG4684	Psort location CytoplasmicMembrane, score
FOC63_RS09925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC63_RS09940	COG0346	lactoylglutathione lyase activity
FOC63_RS09945	COG3764	Sortase (surface protein transpeptidase)
FOC63_RS09985	COG1744	ABC transporter substrate-binding protein PnrA-like
FOC63_RS09990	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOC63_RS09995	COG2813	Specifically methylates the guanine in position
FOC63_RS10000	COG1072	(Pantothenic acid kinase))
FOC63_RS10010	COG5002	protein histidine kinase activity
FOC63_RS10015	COG0745	RESPONSE REGULATOR receiver
FOC63_RS10025	COG0704	Plays a role in the regulation of phosphate uptake
FOC63_RS10030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC63_RS10035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC63_RS10040	COG0581	inorganic phosphate transmembrane transporter activity
FOC63_RS10045	COG0573	inorganic phosphate transmembrane transporter activity
FOC63_RS10065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC63_RS10085	COG0519	Catalyzes the synthesis of GMP from XMP
FOC63_RS10090	COG0483	inositol monophosphate 1-phosphatase activity
FOC63_RS10095	COG4476	Belongs to the UPF0223 family
FOC63_RS10100	COG1393	Belongs to the ArsC family
FOC63_RS10105	COG0196	riboflavin kinase activity
FOC63_RS10110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC63_RS10140	COG1129	ABC transporter
FOC63_RS10155	COG1132	(ABC) transporter
FOC63_RS10160	COG4988	ABC transporter
FOC63_RS10190	COG2873	o-acetylhomoserine
FOC63_RS10200	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOC63_RS10245	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FOC63_RS10255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC63_RS10260	COG1115	amino acid carrier protein
FOC63_RS10305	COG2814	Major facilitator Superfamily
FOC63_RS10320	COG0561	phosphatase activity
FOC63_RS10325	COG0561	phosphatase activity
FOC63_RS10330	COG0110	maltose O-acetyltransferase activity
FOC63_RS10340	COG1028	Short-chain dehydrogenase reductase Sdr
FOC63_RS10350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC63_RS10360	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC63_RS10365	COG3711	transcriptional antiterminator
FOC63_RS10365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC63_RS10370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC63_RS10390	COG2723	6-phospho-beta-galactosidase activity
FOC63_RS10410	COG2190	(PTS) system
FOC63_RS10410	COG1263	PTS System
FOC63_RS10410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC63_RS10415	COG3711	transcriptional antiterminator
FOC63_RS10425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC63_RS10430	COG1177	transmembrane transport
FOC63_RS10435	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC63_RS10445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC63_RS10470	COG0285	dihydrofolate synthase activity
FOC63_RS10480	COG1126	abc transporter atp-binding protein
FOC63_RS10485	COG4215	(ABC) transporter
FOC63_RS10495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC63_RS10500	COG2962	Rard protein
FOC63_RS10515	COG0726	polysaccharide deacetylase
FOC63_RS10520	COG1309	transcriptional regulator
FOC63_RS10535	COG0222	ribosome binding
FOC63_RS10560	COG2040	homocysteine
FOC63_RS10565	COG0833	amino acid
FOC63_RS10585	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC63_RS10590	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOC63_RS10595	COG3425	synthase
FOC63_RS10610	COG1272	protein, Hemolysin III
FOC63_RS10615	COG1304	FMN binding
FOC63_RS10630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOC63_RS10635	COG0435	Glutathione S-transferase
FOC63_RS10640	COG0435	Glutathione S-transferase
FOC63_RS10655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC63_RS10660	COG1126	abc transporter atp-binding protein
FOC63_RS10665	COG0765	amino acid transport
FOC63_RS10670	COG0765	amino acid transport
FOC63_RS10675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC63_RS10685	COG0583	DNA-binding transcription factor activity
FOC63_RS10690	COG0656	L-ascorbic acid biosynthetic process
FOC63_RS10700	COG0745	RESPONSE REGULATOR receiver
FOC63_RS10705	COG2357	RelA SpoT domain protein
FOC63_RS10740	COG1132	(ABC) transporter
FOC63_RS10755	COG0242	peptide deformylase activity
FOC63_RS10760	COG0456	acetyltransferase
FOC63_RS10765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC63_RS10775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC63_RS10780	COG0602	queuosine metabolic process
FOC63_RS10785	COG0720	synthase
FOC63_RS10790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOC63_RS10795	COG1132	(ABC) transporter
FOC63_RS10805	COG0488	(ABC) transporter
FOC63_RS10810	COG0617	tRNA 3'-terminal CCA addition
FOC63_RS10835	COG1388	LysM domain
FOC63_RS10835	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOC63_RS10840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOC63_RS10860	COG0667	Aldo Keto reductase
FOC63_RS10870	COG0646	methionine synthase
FOC63_RS10870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC63_RS10875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOC63_RS10880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC63_RS10880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC63_RS10880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC63_RS10885	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC63_RS10890	COG1349	DNA-binding transcription factor activity
FOC63_RS10895	COG0492	ferredoxin-NADP+ reductase activity
FOC63_RS10900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC63_RS10905	COG0336	Belongs to the RNA methyltransferase TrmD family
FOC63_RS10910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOC63_RS10930	COG1837	Belongs to the UPF0109 family
FOC63_RS10950	COG2136	Putative SAM-dependent methyltransferase
FOC63_RS10950	COG2521	methyltransferase
FOC63_RS10960	COG0577	efflux transmembrane transporter activity
FOC63_RS10965	COG1136	(ABC) transporter
FOC63_RS10980	COG0505	Belongs to the CarA family
FOC63_RS10985	COG0540	Belongs to the ATCase OTCase family
FOC63_RS11000	COG0564	pseudouridine synthase activity
FOC63_RS11010	COG0583	DNA-binding transcription factor activity
FOC63_RS11015	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOC63_RS11040	COG0301	tRNA thio-modification
FOC63_RS11045	COG1104	cysteine desulfurase activity
FOC63_RS11055	COG0285	dihydrofolate synthase activity
FOC63_RS11070	COG0287	Prephenate dehydrogenase
FOC63_RS11080	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOC63_RS11085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOC63_RS11095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC63_RS11100	COG1368	sulfuric ester hydrolase activity
FOC63_RS11105	COG3344	reverse transcriptase
FOC63_RS11110	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOC63_RS11115	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOC63_RS11120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC63_RS11145	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC63_RS11165	COG0463	Glycosyl transferase, family 2
FOC63_RS11180	COG1368	sulfuric ester hydrolase activity
FOC63_RS11190	COG1216	Glycosyl transferase, family 2
FOC63_RS11190	COG1442	glycosyl transferase family 8
FOC63_RS11205	COG0463	Glycosyl transferase, family 2
FOC63_RS11215	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC63_RS11225	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC63_RS11230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC63_RS11235	COG0358	DNA primase activity
FOC63_RS11240	COG1970	mechanosensitive ion channel activity
FOC63_RS11255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC63_RS11260	COG0436	Aminotransferase
FOC63_RS11265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC63_RS11275	COG0058	SHG alpha-glucan phosphorylase activity
FOC63_RS11280	COG1640	4-alpha-glucanotransferase