locus-tag	class	description
SGGB_RS00015	COG0592	DNA-directed DNA polymerase activity
SGGB_RS00030	COG0012	GTP binding
SGGB_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SGGB_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SGGB_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SGGB_RS00190	COG1792	Involved in formation and maintenance of cell shape
SGGB_RS00200	COG3942	CHAP domain
SGGB_RS00210	COG0436	Aminotransferase
SGGB_RS00220	COG0416	fatty acid biosynthetic process
SGGB_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGGB_RS00230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SGGB_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGGB_RS00245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SGGB_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SGGB_RS00265	COG0151	Belongs to the GarS family
SGGB_RS00270	COG1683	Conserved Protein
SGGB_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SGGB_RS00290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SGGB_RS00305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGGB_RS00330	COG2409	Drug exporters of the RND superfamily
SGGB_RS00340	COG2197	response regulator
SGGB_RS00345	COG0583	DNA-binding transcription factor activity
SGGB_RS00360	COG0051	transcription antitermination factor activity, RNA binding
SGGB_RS00370	COG0088	Forms part of the polypeptide exit tunnel
SGGB_RS00375	COG0089	rRNA binding
SGGB_RS00405	COG0255	Belongs to the universal ribosomal protein uL29 family
SGGB_RS00420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SGGB_RS00430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SGGB_RS00450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SGGB_RS00455	COG1841	ribosomal large subunit assembly
SGGB_RS00465	COG0201	protein transport
SGGB_RS00470	COG0563	adenylate kinase activity
SGGB_RS00485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SGGB_RS00490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SGGB_RS00495	COG0202	RNA polymerase activity
SGGB_RS00500	COG0203	ribosomal protein L17
SGGB_RS00585	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SGGB_RS00595	COG1121	(ABC) transporter
SGGB_RS00600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGGB_RS00630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SGGB_RS00635	COG1459	type II secretion system
SGGB_RS00640	COG4537	Required for transformation and DNA binding
SGGB_RS00690	COG1266	CAAX protease self-immunity
SGGB_RS00695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SGGB_RS00700	COG1363	Peptidase, m42
SGGB_RS00705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SGGB_RS00710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGGB_RS00725	COG2391	methyltransferase activity
SGGB_RS00730	COG0425	Belongs to the sulfur carrier protein TusA family
SGGB_RS00735	COG0561	phosphatase activity
SGGB_RS00740	COG1621	beta-fructofuranosidase activity
SGGB_RS00740	COG3583	domain protein
SGGB_RS00740	COG5492	domain, Protein
SGGB_RS00750	COG4585	Histidine kinase
SGGB_RS00755	COG2197	response regulator
SGGB_RS00775	COG3715	PTS system
SGGB_RS00780	COG3716	PTS system mannose fructose sorbose family IID component
SGGB_RS00790	COG4120	Belongs to the binding-protein-dependent transport system permease family
SGGB_RS00795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGGB_RS00810	COG1396	sequence-specific DNA binding
SGGB_RS00820	COG0564	pseudouridine synthase activity
SGGB_RS00830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGGB_RS00850	COG4667	esterase of the alpha-beta hydrolase superfamily
SGGB_RS00860	COG2017	converts alpha-aldose to the beta-anomer
SGGB_RS00870	COG2249	NAD(P)H dehydrogenase (quinone) activity
SGGB_RS00895	COG1396	sequence-specific DNA binding
SGGB_RS00970	COG1674	ftsk spoiiie
SGGB_RS01005	COG2161	toxin-antitoxin pair type II binding
SGGB_RS01055	COG0433	COG0433 Predicted ATPase
SGGB_RS01075	COG3764	Sortase (surface protein transpeptidase)
SGGB_RS01120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SGGB_RS01145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SGGB_RS01150	COG1609	Transcriptional regulator
SGGB_RS01155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS01155	COG2190	(PTS) system
SGGB_RS01155	COG1263	PTS System
SGGB_RS01165	COG1363	Peptidase, m42
SGGB_RS01175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGB_RS01180	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGGB_RS01185	COG2723	6-phospho-beta-galactosidase activity
SGGB_RS01190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGB_RS01195	COG2188	Transcriptional regulator
SGGB_RS01200	COG1482	cell wall glycoprotein biosynthetic process
SGGB_RS01210	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SGGB_RS01215	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SGGB_RS01225	COG1653	transport
SGGB_RS01230	COG1175	transmembrane transport
SGGB_RS01235	COG0395	ABC-type sugar transport system, permease component
SGGB_RS01250	COG2188	Transcriptional regulator
SGGB_RS01255	COG1940	carbohydrate kinase activity
SGGB_RS01285	COG3842	ATPase activity
SGGB_RS01325	COG3775	system Galactitol-specific IIC component
SGGB_RS01335	COG3711	transcriptional antiterminator
SGGB_RS01340	COG2723	6-phospho-beta-galactosidase activity
SGGB_RS01345	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGGB_RS01350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGB_RS01350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGB_RS01355	COG3867	Arabinogalactan endo-beta-1,4-galactanase
SGGB_RS01360	COG2207	Transcriptional regulator
SGGB_RS01365	COG3345	alpha-galactosidase
SGGB_RS01370	COG1653	transport
SGGB_RS01375	COG1175	transmembrane transport
SGGB_RS01380	COG0395	ABC-type sugar transport system, permease component
SGGB_RS01385	COG0366	Alpha amylase catalytic
SGGB_RS01390	COG0366	Alpha amylase catalytic
SGGB_RS01395	COG1609	Transcriptional regulator
SGGB_RS01400	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SGGB_RS01405	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SGGB_RS01410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGGB_RS01420	COG1862	Preprotein translocase
SGGB_RS01425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGGB_RS01430	COG4589	Belongs to the CDS family
SGGB_RS01465	COG0242	peptide deformylase activity
SGGB_RS01485	COG0346	lactoylglutathione lyase activity
SGGB_RS01490	COG0561	phosphatase activity
SGGB_RS01500	COG1454	alcohol dehydrogenase
SGGB_RS01500	COG1012	belongs to the aldehyde dehydrogenase family
SGGB_RS01515	COG1185	polyribonucleotide nucleotidyltransferase activity
SGGB_RS01525	COG1045	serine acetyltransferase
SGGB_RS01535	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SGGB_RS01565	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SGGB_RS01575	COG4974	Belongs to the 'phage' integrase family
SGGB_RS01595	COG3942	CHAP domain
SGGB_RS01595	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGGB_RS01610	COG0433	COG0433 Predicted ATPase
SGGB_RS01625	COG0739	heme binding
SGGB_RS01650	COG1674	ftsk spoiiie
SGGB_RS01685	COG1881	PFAM PEBP family protein
SGGB_RS01690	COG1396	sequence-specific DNA binding
SGGB_RS01770	COG3830	Belongs to the UPF0237 family
SGGB_RS01775	COG2848	UPF0210 protein
SGGB_RS01780	COG0588	phosphoglycerate mutase activity
SGGB_RS01790	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGGB_RS01805	COG0443	Heat shock 70 kDa protein
SGGB_RS01825	COG0351	phosphomethylpyrimidine kinase
SGGB_RS01825	COG0352	thiamine-phosphate diphosphorylase activity
SGGB_RS01840	COG0668	transmembrane transport
SGGB_RS01855	COG0504	CTP synthase activity
SGGB_RS01870	COG0191	fructose-bisphosphate aldolase activity
SGGB_RS01880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SGGB_RS01890	COG1461	Dihydroxyacetone kinase
SGGB_RS01895	COG0129	dihydroxy-acid dehydratase activity
SGGB_RS01900	COG0028	Belongs to the TPP enzyme family
SGGB_RS01905	COG0440	acetolactate synthase activity
SGGB_RS01910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SGGB_RS01915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SGGB_RS01930	COG1126	abc transporter atp-binding protein
SGGB_RS01935	COG0765	amino acid transport
SGGB_RS01955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGGB_RS01965	COG0719	Fe-S assembly protein
SGGB_RS01970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGGB_RS01980	COG0719	Fe-S assembly protein
SGGB_RS01985	COG1686	Belongs to the peptidase S11 family
SGGB_RS01990	COG4166	transmembrane transport
SGGB_RS01995	COG0601	transmembrane transport
SGGB_RS02000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGGB_RS02005	COG0444	Belongs to the ABC transporter superfamily
SGGB_RS02010	COG4608	Belongs to the ABC transporter superfamily
SGGB_RS02045	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SGGB_RS02045	COG2755	lipolytic protein G-D-S-L family
SGGB_RS02050	COG0527	aspartate kinase activity
SGGB_RS02055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGGB_RS02060	COG1024	Enoyl-CoA hydratase
SGGB_RS02070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGGB_RS02080	COG2070	2-Nitropropane dioxygenase
SGGB_RS02085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SGGB_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
SGGB_RS02095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGGB_RS02110	COG0439	Biotin carboxylase
SGGB_RS02125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SGGB_RS02135	COG3716	PTS system mannose fructose sorbose family IID component
SGGB_RS02140	COG3715	PTS system
SGGB_RS02150	COG0561	phosphatase activity
SGGB_RS02165	COG2252	PERMEase
SGGB_RS02170	COG0802	atpase or kinase
SGGB_RS02180	COG1316	TRANSCRIPTIONal
SGGB_RS02190	COG0537	adenosine 5'-monophosphoramidase activity
SGGB_RS02195	COG1131	(ABC) transporter
SGGB_RS02200	COG4473	ABC transporter
SGGB_RS02210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SGGB_RS02220	COG3300	MHYT domain
SGGB_RS02220	COG5001	Diguanylate cyclase
SGGB_RS02245	COG0195	Participates in both transcription termination and antitermination
SGGB_RS02250	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SGGB_RS02260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SGGB_RS02265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SGGB_RS02275	COG2801	Transposase and inactivated derivatives
SGGB_RS02295	COG2217	Heavy metal translocating P-type atpase
SGGB_RS02305	COG2860	membrane
SGGB_RS02310	COG0561	phosphatase activity
SGGB_RS02320	COG1309	transcriptional regulator
SGGB_RS02345	COG1283	sodium-dependent phosphate transmembrane transporter activity
SGGB_RS02370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGB_RS02370	COG3711	transcriptional antiterminator
SGGB_RS02380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SGGB_RS02380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGB_RS02380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGB_RS02395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SGGB_RS02415	COG1131	(ABC) transporter
SGGB_RS02425	COG1263	PTS System
SGGB_RS02425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS02430	COG1737	Transcriptional regulator
SGGB_RS02435	COG2723	6-phospho-beta-galactosidase activity
SGGB_RS02440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SGGB_RS02445	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SGGB_RS02460	COG0768	penicillin binding
SGGB_RS02465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGGB_RS02470	COG0513	Belongs to the DEAD box helicase family
SGGB_RS02485	COG1126	abc transporter atp-binding protein
SGGB_RS02500	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SGGB_RS02505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SGGB_RS02510	COG3579	cysteine-type endopeptidase activity
SGGB_RS02515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGGB_RS02520	COG3331	DNA recombination
SGGB_RS02530	COG3599	regulation of cell shape
SGGB_RS02535	COG0116	Belongs to the methyltransferase superfamily
SGGB_RS02550	COG1854	S-ribosylhomocysteine lyase activity
SGGB_RS02570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SGGB_RS02575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SGGB_RS02580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SGGB_RS02580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGGB_RS02600	COG4585	Histidine kinase
SGGB_RS02605	COG2197	response regulator
SGGB_RS02615	COG1098	S1 RNA binding domain
SGGB_RS02625	COG1739	Uncharacterized protein family UPF0029
SGGB_RS02630	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SGGB_RS02635	COG1040	competence protein
SGGB_RS02705	COG3557	Belongs to the UPF0374 family
SGGB_RS02710	COG2137	regulation of response to DNA damage stimulus
SGGB_RS02720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGGB_RS02750	COG1428	Deoxynucleoside kinase
SGGB_RS02775	COG0519	Catalyzes the synthesis of GMP from XMP
SGGB_RS02785	COG0525	valine-tRNA ligase activity
SGGB_RS02805	COG1309	transcriptional regulator
SGGB_RS02825	COG0742	ribosomal rna small subunit methyltransferase
SGGB_RS02830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SGGB_RS02835	COG3480	Lon protease (S16) C-terminal proteolytic domain
SGGB_RS02845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SGGB_RS02855	COG0737	Belongs to the 5'-nucleotidase family
SGGB_RS02860	COG4470	Protein conserved in bacteria
SGGB_RS02875	COG1132	(ABC) transporter
SGGB_RS02880	COG1132	(ABC) transporter
SGGB_RS02885	COG1131	(ABC) transporter
SGGB_RS02895	COG4585	Histidine kinase
SGGB_RS02900	COG2197	response regulator
SGGB_RS02905	COG4842	Belongs to the WXG100 family
SGGB_RS02920	COG4499	WXG100 protein secretion system (Wss), protein YukC
SGGB_RS02925	COG1674	ftsk spoiiie
SGGB_RS03050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGGB_RS03055	COG0512	Glutamine amidotransferase of anthranilate synthase
SGGB_RS03065	COG0134	indole-3-glycerol-phosphate synthase activity
SGGB_RS03070	COG0135	phosphoribosylanthranilate isomerase activity
SGGB_RS03075	COG0133	tryptophan synthase activity
SGGB_RS03080	COG0159	tryptophan synthase activity
SGGB_RS03085	COG1914	H( )-stimulated, divalent metal cation uptake system
SGGB_RS03095	COG0783	Belongs to the Dps family
SGGB_RS03105	COG1940	carbohydrate kinase activity
SGGB_RS03110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SGGB_RS03130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGB_RS03135	COG2207	Transcriptional regulator
SGGB_RS03140	COG1217	gtp-binding protein TYPA
SGGB_RS03175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SGGB_RS03180	COG1799	cell septum assembly
SGGB_RS03195	COG3599	regulation of cell shape
SGGB_RS03215	COG0542	response to heat
SGGB_RS03230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SGGB_RS03235	COG4703	Protein of unknown function (DUF1797)
SGGB_RS03240	COG0765	amino acid transport
SGGB_RS03245	COG1126	abc transporter atp-binding protein
SGGB_RS03270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SGGB_RS03300	COG1376	ErfK ybiS ycfS ynhG family protein
SGGB_RS03320	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SGGB_RS03325	COG1438	arginine binding
SGGB_RS03330	COG0497	DNA recombination
SGGB_RS03335	COG1307	EDD domain protein, DegV family
SGGB_RS03340	COG2755	lipolytic protein G-D-S-L family
SGGB_RS03345	COG4698	Protein conserved in bacteria
SGGB_RS03365	COG3104	oligopeptide transport
SGGB_RS03370	COG0167	dihydroorotate dehydrogenase activity
SGGB_RS03375	COG0604	alcohol dehydrogenase
SGGB_RS03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGGB_RS03375	COG3321	synthase
SGGB_RS03375	COG4221	oxidoreductase activity
SGGB_RS03380	COG0640	Transcriptional regulator
SGGB_RS03385	COG2217	Heavy metal translocating P-type atpase
SGGB_RS03390	COG2076	Multidrug Resistance protein
SGGB_RS03415	COG1827	regulation of RNA biosynthetic process
SGGB_RS03425	COG0768	penicillin binding
SGGB_RS03430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SGGB_RS03435	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGGB_RS03445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SGGB_RS03460	COG0513	Belongs to the DEAD box helicase family
SGGB_RS03470	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SGGB_RS03475	COG0204	Acyl-transferase
SGGB_RS03480	COG1555	photosystem II stabilization
SGGB_RS03480	COG1596	polysaccharide export
SGGB_RS03485	COG2333	competence protein COMEC
SGGB_RS03485	COG0658	competence protein
SGGB_RS03495	COG1598	PFAM Uncharacterised protein family UPF0150
SGGB_RS03510	COG1466	dna polymerase III delta subunit
SGGB_RS03515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SGGB_RS03520	COG0217	transcriptional regulatory protein
SGGB_RS03535	COG0363	glucosamine-6-phosphate deaminase activity
SGGB_RS03540	COG1187	pseudouridine synthase activity
SGGB_RS03560	COG0546	phosphoglycolate phosphatase activity
SGGB_RS03565	COG4122	O-methyltransferase activity
SGGB_RS03575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SGGB_RS03585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGGB_RS03590	COG0436	Aminotransferase
SGGB_RS03610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SGGB_RS03615	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SGGB_RS03620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGGB_RS03625	COG2249	NAD(P)H dehydrogenase (quinone) activity
SGGB_RS03630	COG1902	pentaerythritol trinitrate reductase activity
SGGB_RS03640	COG0789	Transcriptional regulator
SGGB_RS03650	COG1476	TRANSCRIPTIONal
SGGB_RS03660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGGB_RS03660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGGB_RS03665	COG0307	riboflavin synthase, alpha
SGGB_RS03670	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGGB_RS03670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGGB_RS03690	COG0656	L-ascorbic acid biosynthetic process
SGGB_RS03695	COG0656	L-ascorbic acid biosynthetic process
SGGB_RS03710	COG3859	Proton-coupled thiamine transporter YuaJ
SGGB_RS03715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGGB_RS03720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGGB_RS03725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SGGB_RS03730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SGGB_RS03735	COG0372	Belongs to the citrate synthase family
SGGB_RS03755	COG1609	Transcriptional regulator
SGGB_RS03760	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SGGB_RS03765	COG0251	oxidation-reduction process
SGGB_RS03775	COG1309	transcriptional regulator
SGGB_RS03830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGGB_RS03835	COG1660	Displays ATPase and GTPase activities
SGGB_RS03865	COG1396	sequence-specific DNA binding
SGGB_RS03890	COG1388	LysM domain
SGGB_RS03890	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGGB_RS03900	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SGGB_RS03920	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SGGB_RS03945	COG1609	Transcriptional regulator
SGGB_RS03955	COG2182	Extracellular solute-binding protein
SGGB_RS03960	COG1175	transmembrane transport
SGGB_RS03965	COG3833	ABC-type maltose transport systems, permease component
SGGB_RS03990	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SGGB_RS03995	COG0066	3-isopropylmalate dehydratase activity
SGGB_RS04000	COG1956	GAF domain-containing protein
SGGB_RS04005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SGGB_RS04015	COG2801	Transposase and inactivated derivatives
SGGB_RS04025	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SGGB_RS04025	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SGGB_RS04030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SGGB_RS04045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGGB_RS04055	COG4109	DRTGG domain
SGGB_RS04060	COG0024	Methionine aminopeptidase
SGGB_RS04070	COG2246	polysaccharide biosynthetic process
SGGB_RS04075	COG4708	membrane
SGGB_RS04080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGGB_RS04085	COG1597	lipid kinase activity
SGGB_RS04090	COG1523	belongs to the glycosyl hydrolase 13 family
SGGB_RS04095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SGGB_RS04100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SGGB_RS04110	COG0297	glycogen (starch) synthase activity
SGGB_RS04115	COG0058	SHG alpha-glucan phosphorylase activity
SGGB_RS04125	COG0356	it plays a direct role in the translocation of protons across the membrane
SGGB_RS04130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SGGB_RS04165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGGB_RS04180	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SGGB_RS04185	COG0456	acetyltransferase
SGGB_RS04195	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SGGB_RS04200	COG1074	ATP-dependent DNA helicase activity
SGGB_RS04225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SGGB_RS04240	COG0300	oxidoreductase activity
SGGB_RS04245	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SGGB_RS04245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SGGB_RS04270	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SGGB_RS04310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SGGB_RS04315	COG2384	SAM-dependent methyltransferase
SGGB_RS04325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SGGB_RS04335	COG0135	phosphoribosylanthranilate isomerase activity
SGGB_RS04340	COG1088	dTDP-glucose 4,6-dehydratase activity
SGGB_RS04350	COG1051	belongs to the nudix hydrolase family
SGGB_RS04355	COG0628	permease
SGGB_RS04360	COG0457	Tetratricopeptide repeat
SGGB_RS04370	COG0640	Transcriptional regulator
SGGB_RS04380	COG0028	Belongs to the TPP enzyme family
SGGB_RS04385	COG3527	Alpha-acetolactate decarboxylase
SGGB_RS04390	COG0531	amino acid
SGGB_RS04395	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SGGB_RS04400	COG0583	DNA-binding transcription factor activity
SGGB_RS04405	COG1126	abc transporter atp-binding protein
SGGB_RS04410	COG0765	amino acid transport
SGGB_RS04415	COG1834	amidinotransferase
SGGB_RS04420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGGB_RS04425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGGB_RS04430	COG4187	Peptidase family M20/M25/M40
SGGB_RS04440	COG4120	Belongs to the binding-protein-dependent transport system permease family
SGGB_RS04445	COG3842	ATPase activity
SGGB_RS04490	COG0488	(ABC) transporter
SGGB_RS04500	COG1132	(ABC) transporter
SGGB_RS04505	COG1132	(ABC) transporter
SGGB_RS04515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SGGB_RS04520	COG0022	dehydrogenase e1 component
SGGB_RS04520	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGGB_RS04530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGGB_RS04535	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGGB_RS04540	COG4605	iron ion homeostasis
SGGB_RS04545	COG4604	ABC transporter, ATP-binding protein
SGGB_RS04555	COG0697	spore germination
SGGB_RS04560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGGB_RS04565	COG0095	Lipoate-protein ligase
SGGB_RS04580	COG0583	DNA-binding transcription factor activity
SGGB_RS04590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SGGB_RS04620	COG2814	Major facilitator Superfamily
SGGB_RS04635	COG0477	Major facilitator Superfamily
SGGB_RS04640	COG3976	FMN-binding domain protein
SGGB_RS04640	COG0431	NADPH-dependent FMN reductase
SGGB_RS04640	COG1053	succinate dehydrogenase
SGGB_RS04650	COG3976	FMN-binding domain protein
SGGB_RS04650	COG1053	succinate dehydrogenase
SGGB_RS04650	COG0431	NADPH-dependent FMN reductase
SGGB_RS04655	COG3976	FMN-binding domain protein
SGGB_RS04655	COG1053	succinate dehydrogenase
SGGB_RS04655	COG0431	NADPH-dependent FMN reductase
SGGB_RS04665	COG1937	Protein conserved in bacteria
SGGB_RS04675	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGGB_RS04685	COG1418	mRNA catabolic process
SGGB_RS04705	COG0583	DNA-binding transcription factor activity
SGGB_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
SGGB_RS04720	COG1979	alcohol dehydrogenase
SGGB_RS04735	COG0789	Transcriptional regulator
SGGB_RS04740	COG0656	L-ascorbic acid biosynthetic process
SGGB_RS04765	COG1011	Hydrolase
SGGB_RS04775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SGGB_RS04785	COG0583	DNA-binding transcription factor activity
SGGB_RS04790	COG2855	membrane
SGGB_RS04795	COG1012	belongs to the aldehyde dehydrogenase family
SGGB_RS04805	COG0322	excinuclease ABC activity
SGGB_RS04835	COG1573	uracil-dna glycosylase
SGGB_RS04860	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SGGB_RS04865	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SGGB_RS04895	COG1316	TRANSCRIPTIONal
SGGB_RS04905	COG3944	biosynthesis protein
SGGB_RS04915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGGB_RS04920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SGGB_RS04935	COG0438	transferase activity, transferring glycosyl groups
SGGB_RS04940	COG1442	glycosyl transferase family 8
SGGB_RS04940	COG1216	Glycosyl transferase, family 2
SGGB_RS04970	COG1216	Glycosyl transferase, family 2
SGGB_RS04970	COG1442	glycosyl transferase family 8
SGGB_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
SGGB_RS04990	COG2337	Toxic component of a toxin-antitoxin (TA) module
SGGB_RS05010	COG2801	Transposase and inactivated derivatives
SGGB_RS05020	COG0167	dihydroorotate dehydrogenase activity
SGGB_RS05025	COG0284	orotidine-5'-phosphate decarboxylase activity
SGGB_RS05030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SGGB_RS05040	COG1881	PFAM PEBP family protein
SGGB_RS05060	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SGGB_RS05065	COG0187	DNA topoisomerase II activity
SGGB_RS05070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGGB_RS05075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SGGB_RS05095	COG0539	negative regulation of cytoplasmic translation
SGGB_RS05105	COG1346	cytolysis
SGGB_RS05125	COG1131	(ABC) transporter
SGGB_RS05130	COG1725	Transcriptional regulator
SGGB_RS05140	COG0205	6-phosphofructokinase activity
SGGB_RS05145	COG0469	pyruvate kinase activity
SGGB_RS05160	COG2213	PTS system mannitol-specific
SGGB_RS05165	COG3711	transcriptional antiterminator
SGGB_RS05170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGB_RS05175	COG0246	Mannitol dehydrogenase
SGGB_RS05180	COG2824	Alkylphosphonate utilization operon protein PhnA
SGGB_RS05185	COG0765	amino acid transport
SGGB_RS05190	COG1126	abc transporter atp-binding protein
SGGB_RS05195	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SGGB_RS05205	COG1115	amino acid carrier protein
SGGB_RS05210	COG2723	6-phospho-beta-galactosidase activity
SGGB_RS05220	COG0406	alpha-ribazole phosphatase activity
SGGB_RS05230	COG0628	permease
SGGB_RS05235	COG1442	glycosyl transferase family 8
SGGB_RS05245	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SGGB_RS05255	COG1104	cysteine desulfurase activity
SGGB_RS05270	COG2357	RelA SpoT domain protein
SGGB_RS05280	COG0564	pseudouridine synthase activity
SGGB_RS05285	COG0280	phosphate acetyltransferase
SGGB_RS05290	COG4221	oxidoreductase activity
SGGB_RS05300	COG0561	phosphatase activity
SGGB_RS05305	COG2723	6-phospho-beta-galactosidase activity
SGGB_RS05310	COG1136	(ABC) transporter
SGGB_RS05315	COG0577	efflux transmembrane transporter activity
SGGB_RS05320	COG0516	GMP reductase activity
SGGB_RS05325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SGGB_RS05345	COG2233	PERMEase
SGGB_RS05375	COG2890	protein-(glutamine-N5) methyltransferase activity
SGGB_RS05380	COG0009	L-threonylcarbamoyladenylate synthase
SGGB_RS05405	COG1132	(ABC) transporter
SGGB_RS05425	COG3711	transcriptional antiterminator
SGGB_RS05440	COG2723	6-phospho-beta-galactosidase activity
SGGB_RS05445	COG0519	Catalyzes the synthesis of GMP from XMP
SGGB_RS05445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SGGB_RS05450	COG4106	trans-aconitate 2-methyltransferase activity
SGGB_RS05460	COG1819	glycosyl
SGGB_RS05465	COG1396	sequence-specific DNA binding
SGGB_RS05470	COG5263	repeat protein
SGGB_RS05470	COG0366	Alpha amylase catalytic
SGGB_RS05475	COG1396	sequence-specific DNA binding
SGGB_RS05480	COG0366	Alpha amylase catalytic
SGGB_RS05480	COG5263	repeat protein
SGGB_RS05490	COG0534	Mate efflux family protein
SGGB_RS05500	COG2376	Dihydroxyacetone kinase
SGGB_RS05505	COG1309	transcriptional regulator
SGGB_RS05510	COG2376	Dihydroxyacetone kinase
SGGB_RS05515	COG1461	Dihydroxyacetone kinase
SGGB_RS05520	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SGGB_RS05525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SGGB_RS05540	COG5290	Psort location Cytoplasmic, score
SGGB_RS05545	COG2188	Transcriptional regulator
SGGB_RS05560	COG0673	inositol 2-dehydrogenase activity
SGGB_RS05570	COG0673	inositol 2-dehydrogenase activity
SGGB_RS05575	COG4115	mRNA cleavage
SGGB_RS05585	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SGGB_RS05590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SGGB_RS05600	COG1132	(ABC) transporter
SGGB_RS05605	COG4974	Belongs to the 'phage' integrase family
SGGB_RS05615	COG5002	protein histidine kinase activity
SGGB_RS05620	COG0745	RESPONSE REGULATOR receiver
SGGB_RS05625	COG0577	efflux transmembrane transporter activity
SGGB_RS05630	COG1136	(ABC) transporter
SGGB_RS05640	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SGGB_RS05660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SGGB_RS05665	COG0758	DNA mediated transformation
SGGB_RS05670	COG0110	maltose O-acetyltransferase activity
SGGB_RS05675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SGGB_RS05680	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SGGB_RS05725	COG1131	(ABC) transporter
SGGB_RS05730	COG0488	(ABC) transporter
SGGB_RS05745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGGB_RS05750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGGB_RS05755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SGGB_RS05760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SGGB_RS05795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SGGB_RS05800	COG4684	Psort location CytoplasmicMembrane, score
SGGB_RS05805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGGB_RS05820	COG0346	lactoylglutathione lyase activity
SGGB_RS05825	COG3764	Sortase (surface protein transpeptidase)
SGGB_RS05845	COG2801	Transposase and inactivated derivatives
SGGB_RS05855	COG1079	Belongs to the binding-protein-dependent transport system permease family
SGGB_RS05860	COG4603	Belongs to the binding-protein-dependent transport system permease family
SGGB_RS05865	COG3845	ABC transporter
SGGB_RS05870	COG1744	ABC transporter substrate-binding protein PnrA-like
SGGB_RS05875	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SGGB_RS05880	COG2813	Specifically methylates the guanine in position
SGGB_RS05885	COG1072	(Pantothenic acid kinase))
SGGB_RS05895	COG5002	protein histidine kinase activity
SGGB_RS05910	COG0704	Plays a role in the regulation of phosphate uptake
SGGB_RS05915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGGB_RS05920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGGB_RS05925	COG0581	inorganic phosphate transmembrane transporter activity
SGGB_RS05930	COG0573	inorganic phosphate transmembrane transporter activity
SGGB_RS05950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGGB_RS05970	COG0519	Catalyzes the synthesis of GMP from XMP
SGGB_RS05975	COG0483	inositol monophosphate 1-phosphatase activity
SGGB_RS05980	COG4476	Belongs to the UPF0223 family
SGGB_RS05985	COG1393	Belongs to the ArsC family
SGGB_RS05990	COG0196	riboflavin kinase activity
SGGB_RS05995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SGGB_RS06025	COG1129	ABC transporter
SGGB_RS06045	COG4988	ABC transporter
SGGB_RS06075	COG2873	o-acetylhomoserine
SGGB_RS06085	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SGGB_RS06130	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SGGB_RS06140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGGB_RS06145	COG1115	amino acid carrier protein
SGGB_RS06170	COG0561	phosphatase activity
SGGB_RS06190	COG2814	Major facilitator Superfamily
SGGB_RS06205	COG0561	phosphatase activity
SGGB_RS06210	COG0561	phosphatase activity
SGGB_RS06215	COG0110	maltose O-acetyltransferase activity
SGGB_RS06225	COG1028	Short-chain dehydrogenase reductase Sdr
SGGB_RS06235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGB_RS06245	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGGB_RS06250	COG3711	transcriptional antiterminator
SGGB_RS06250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGB_RS06255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGB_RS06275	COG2723	6-phospho-beta-galactosidase activity
SGGB_RS06295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS06295	COG2190	(PTS) system
SGGB_RS06295	COG1263	PTS System
SGGB_RS06300	COG3711	transcriptional antiterminator
SGGB_RS06315	COG1177	transmembrane transport
SGGB_RS06320	COG1176	ABC-type spermidine putrescine transport system, permease component I
SGGB_RS06330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SGGB_RS06355	COG0285	dihydrofolate synthase activity
SGGB_RS06360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGB_RS06365	COG1126	abc transporter atp-binding protein
SGGB_RS06370	COG4215	(ABC) transporter
SGGB_RS06380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGGB_RS06385	COG2962	Rard protein
SGGB_RS06400	COG0726	polysaccharide deacetylase
SGGB_RS06415	COG1309	transcriptional regulator
SGGB_RS06430	COG0222	ribosome binding
SGGB_RS06455	COG2040	homocysteine
SGGB_RS06460	COG0833	amino acid
SGGB_RS06480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SGGB_RS06485	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SGGB_RS06490	COG3425	synthase
SGGB_RS06505	COG1272	protein, Hemolysin III
SGGB_RS06510	COG1304	FMN binding
SGGB_RS06525	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SGGB_RS06530	COG0435	Glutathione S-transferase
SGGB_RS06535	COG0435	Glutathione S-transferase
SGGB_RS06550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGB_RS06555	COG1126	abc transporter atp-binding protein
SGGB_RS06560	COG0765	amino acid transport
SGGB_RS06565	COG0765	amino acid transport
SGGB_RS06570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGB_RS06580	COG0583	DNA-binding transcription factor activity
SGGB_RS06585	COG0656	L-ascorbic acid biosynthetic process
SGGB_RS06595	COG0745	RESPONSE REGULATOR receiver
SGGB_RS06600	COG2357	RelA SpoT domain protein
SGGB_RS06635	COG1132	(ABC) transporter
SGGB_RS06650	COG0242	peptide deformylase activity
SGGB_RS06655	COG0456	acetyltransferase
SGGB_RS06660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SGGB_RS06670	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SGGB_RS06675	COG0602	queuosine metabolic process
SGGB_RS06680	COG0720	synthase
SGGB_RS06685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SGGB_RS06690	COG1132	(ABC) transporter
SGGB_RS06700	COG0488	(ABC) transporter
SGGB_RS06705	COG0617	tRNA 3'-terminal CCA addition
SGGB_RS06730	COG1388	LysM domain
SGGB_RS06730	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGGB_RS06735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SGGB_RS06755	COG0667	Aldo Keto reductase
SGGB_RS06765	COG0646	methionine synthase
SGGB_RS06765	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SGGB_RS06770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SGGB_RS06775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGB_RS06775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGB_RS06775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGB_RS06780	COG1105	Belongs to the carbohydrate kinase PfkB family
SGGB_RS06785	COG1349	DNA-binding transcription factor activity
SGGB_RS06790	COG0492	ferredoxin-NADP+ reductase activity
SGGB_RS06805	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SGGB_RS06820	COG1837	Belongs to the UPF0109 family
SGGB_RS06840	COG2136	Putative SAM-dependent methyltransferase
SGGB_RS06840	COG2521	methyltransferase
SGGB_RS06850	COG0577	efflux transmembrane transporter activity
SGGB_RS06855	COG1136	(ABC) transporter
SGGB_RS06870	COG0505	Belongs to the CarA family
SGGB_RS06875	COG0540	Belongs to the ATCase OTCase family
SGGB_RS06890	COG0564	pseudouridine synthase activity
SGGB_RS06900	COG0583	DNA-binding transcription factor activity
SGGB_RS06905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SGGB_RS06930	COG0301	tRNA thio-modification
SGGB_RS06935	COG1104	cysteine desulfurase activity
SGGB_RS06945	COG0285	dihydrofolate synthase activity
SGGB_RS06960	COG0287	Prephenate dehydrogenase
SGGB_RS06970	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGGB_RS06975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SGGB_RS06985	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SGGB_RS06990	COG1368	sulfuric ester hydrolase activity
SGGB_RS06995	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SGGB_RS07000	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SGGB_RS07005	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SGGB_RS07025	COG2195	Cleaves the N-terminal amino acid of tripeptides
SGGB_RS07040	COG3942	CHAP domain
SGGB_RS07050	COG0463	Glycosyl transferase, family 2
SGGB_RS07065	COG1368	sulfuric ester hydrolase activity
SGGB_RS07075	COG1216	Glycosyl transferase, family 2
SGGB_RS07075	COG1442	glycosyl transferase family 8
SGGB_RS07090	COG0463	Glycosyl transferase, family 2
SGGB_RS07100	COG1091	dTDP-4-dehydrorhamnose reductase activity
SGGB_RS07105	COG2151	metal-sulfur cluster biosynthetic enzyme
SGGB_RS07110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGGB_RS07115	COG0358	DNA primase activity
SGGB_RS07120	COG1970	mechanosensitive ion channel activity
SGGB_RS07150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGB_RS07155	COG0436	Aminotransferase
SGGB_RS07160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGB_RS07170	COG0058	SHG alpha-glucan phosphorylase activity
SGGB_RS07175	COG1640	4-alpha-glucanotransferase
SGGB_RS07180	COG1609	Transcriptional regulator
SGGB_RS07190	COG1175	transmembrane transport
SGGB_RS07195	COG3833	ABC-type maltose transport systems, permease component
SGGB_RS07200	COG2816	NAD+ diphosphatase activity
SGGB_RS07210	COG0556	nucleotide-excision repair
SGGB_RS07215	COG0765	amino acid transport
SGGB_RS07220	COG1126	abc transporter atp-binding protein
SGGB_RS07225	COG0488	(ABC) transporter
SGGB_RS07240	COG1187	pseudouridine synthase activity
SGGB_RS07245	COG4166	transmembrane transport
SGGB_RS07250	COG4166	transmembrane transport
SGGB_RS07265	COG0659	secondary active sulfate transmembrane transporter activity
SGGB_RS07275	COG0590	tRNA wobble adenosine to inosine editing
SGGB_RS07330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGGB_RS07335	COG1316	TRANSCRIPTIONal
SGGB_RS07340	COG0077	Prephenate dehydratase
SGGB_RS07345	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SGGB_RS07350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGGB_RS07355	COG0481	GTPase activity
SGGB_RS07370	COG1518	maintenance of DNA repeat elements
SGGB_RS07405	COG1518	maintenance of DNA repeat elements
SGGB_RS07410	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SGGB_RS07425	COG0647	UMP catabolic process
SGGB_RS07430	COG1051	belongs to the nudix hydrolase family
SGGB_RS07440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SGGB_RS07445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGGB_RS07455	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SGGB_RS07465	COG3442	glutamine amidotransferase
SGGB_RS07470	COG0148	phosphopyruvate hydratase activity
SGGB_RS07490	COG1523	belongs to the glycosyl hydrolase 13 family
SGGB_RS07505	COG0107	imidazoleglycerol-phosphate synthase activity
SGGB_RS07515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SGGB_RS07525	COG0560	Phosphoserine phosphatase
SGGB_RS07530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SGGB_RS07540	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SGGB_RS07560	COG0187	DNA topoisomerase II activity
SGGB_RS07570	COG0772	Belongs to the SEDS family
SGGB_RS07585	COG0038	chloride channel
SGGB_RS07590	COG0287	Prephenate dehydrogenase
SGGB_RS07590	COG1605	Chorismate mutase
SGGB_RS07605	COG0716	FMN binding
SGGB_RS07620	COG0017	Asparaginyl-tRNA synthetase
SGGB_RS07630	COG0436	Aminotransferase
SGGB_RS07640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SGGB_RS07640	COG1199	ATP-dependent helicase activity
SGGB_RS07655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SGGB_RS07675	COG2177	Part of the ABC transporter FtsEX involved in
SGGB_RS07680	COG2884	Cell division ATP-binding protein ftsE
SGGB_RS07685	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SGGB_RS07690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGGB_RS07715	COG1078	dGTPase activity
SGGB_RS07740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SGGB_RS07755	COG0772	Belongs to the SEDS family
SGGB_RS07765	COG1164	Oligoendopeptidase f
SGGB_RS07770	COG0386	Belongs to the glutathione peroxidase family
SGGB_RS07790	COG0588	phosphoglycerate mutase activity
SGGB_RS07820	COG1268	BioY protein
SGGB_RS07825	COG4443	Transcriptional Coactivator p15 (PC4)
SGGB_RS07835	COG0826	peptidase U32
SGGB_RS07880	COG2183	response to ionizing radiation
SGGB_RS07890	COG0701	Predicted permease
SGGB_RS07895	COG3689	TIGRFAM TIGR03943 family protein
SGGB_RS07900	COG3321	synthase
SGGB_RS07900	COG0604	alcohol dehydrogenase
SGGB_RS07905	COG0789	Transcriptional regulator
SGGB_RS07915	COG0552	protein localization to endoplasmic reticulum
SGGB_RS07920	COG0561	phosphatase activity
SGGB_RS07925	COG0561	phosphatase activity
SGGB_RS07935	COG1196	nuclear chromosome segregation
SGGB_RS07945	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SGGB_RS07950	COG5002	protein histidine kinase activity
SGGB_RS07955	COG0745	RESPONSE REGULATOR receiver
SGGB_RS07960	COG1126	abc transporter atp-binding protein
SGGB_RS07965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGB_RS07970	COG0765	amino acid transport
SGGB_RS07975	COG0765	amino acid transport
SGGB_RS08000	COG0745	RESPONSE REGULATOR receiver
SGGB_RS08025	COG4716	Myosin-crossreactive antigen
SGGB_RS08090	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SGGB_RS08095	COG0438	transferase activity, transferring glycosyl groups
SGGB_RS08105	COG1609	Transcriptional regulator
SGGB_RS08110	COG0006	proline dipeptidase activity
SGGB_RS08120	COG2816	NAD+ diphosphatase activity
SGGB_RS08165	COG0741	lytic transglycosylase activity
SGGB_RS08165	COG0791	NLP P60 protein
SGGB_RS08195	COG2946	Replication initiation factor
SGGB_RS08200	COG1674	ftsk spoiiie
SGGB_RS08220	COG1263	PTS System
SGGB_RS08220	COG2190	(PTS) system
SGGB_RS08220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS08240	COG0583	DNA-binding transcription factor activity
SGGB_RS08245	COG0534	Mate efflux family protein
SGGB_RS08255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGGB_RS08280	COG0667	Aldo Keto reductase
SGGB_RS08290	COG2211	Major facilitator Superfamily
SGGB_RS08300	COG3394	polysaccharide catabolic process
SGGB_RS08305	COG1263	PTS System
SGGB_RS08305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS08305	COG2190	(PTS) system
SGGB_RS08320	COG1263	PTS System
SGGB_RS08320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS08320	COG2190	(PTS) system
SGGB_RS08340	COG0163	prenyltransferase activity
SGGB_RS08345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SGGB_RS08350	COG0583	DNA-binding transcription factor activity
SGGB_RS08355	COG1811	Na channel or pump
SGGB_RS08370	COG0778	Nitroreductase
SGGB_RS08375	COG2723	6-phospho-beta-galactosidase activity
SGGB_RS08380	COG1263	PTS System
SGGB_RS08380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS08380	COG2190	(PTS) system
SGGB_RS08395	COG0557	exoribonuclease II activity
SGGB_RS08405	COG2814	Major facilitator Superfamily
SGGB_RS08410	COG0237	dephospho-CoA kinase activity
SGGB_RS08415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGGB_RS08425	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SGGB_RS08430	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SGGB_RS08435	COG0366	Alpha amylase catalytic
SGGB_RS08450	COG1702	phosphate starvation-inducible protein PhoH
SGGB_RS08460	COG4479	Belongs to the UPF0346 family
SGGB_RS08470	COG2996	Protein conserved in bacteria
SGGB_RS08505	COG0582	viral genome integration into host DNA
SGGB_RS08535	COG3764	Sortase (surface protein transpeptidase)
SGGB_RS08550	COG0433	COG0433 Predicted ATPase
SGGB_RS08595	COG2801	Transposase and inactivated derivatives
SGGB_RS08605	COG3620	sequence-specific DNA binding
SGGB_RS08625	COG1674	ftsk spoiiie
SGGB_RS08680	COG1396	sequence-specific DNA binding
SGGB_RS08705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGGB_RS08715	COG2223	nitrite transmembrane transporter activity
SGGB_RS08725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SGGB_RS08750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SGGB_RS08765	COG1028	Short-chain dehydrogenase reductase Sdr
SGGB_RS08780	COG1695	Transcriptional regulator
SGGB_RS08795	COG0534	Mate efflux family protein
SGGB_RS08805	COG0708	Exodeoxyribonuclease III
SGGB_RS08810	COG2814	Major facilitator Superfamily
SGGB_RS08830	COG0656	L-ascorbic acid biosynthetic process
SGGB_RS08840	COG0583	DNA-binding transcription factor activity
SGGB_RS08845	COG1393	Belongs to the ArsC family
SGGB_RS08850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGGB_RS08860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGGB_RS08885	COG0004	ammonium transporteR
SGGB_RS08900	COG1774	PSP1 C-terminal conserved region
SGGB_RS08905	COG0470	DNA polymerase III
SGGB_RS08915	COG0517	IMP dehydrogenase activity
SGGB_RS08915	COG1227	inorganic diphosphatase activity
SGGB_RS08965	COG0583	DNA-binding transcription factor activity
SGGB_RS08970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SGGB_RS08975	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SGGB_RS08980	COG0626	cystathionine gamma-synthase activity
SGGB_RS08985	COG2244	polysaccharide biosynthetic process
SGGB_RS08990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SGGB_RS08995	COG1120	ATPase activity
SGGB_RS09000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGGB_RS09005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGGB_RS09010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGGB_RS09035	COG1227	inorganic diphosphatase activity
SGGB_RS09045	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SGGB_RS09050	COG1253	flavin adenine dinucleotide binding
SGGB_RS09055	COG1119	ATPase activity
SGGB_RS09060	COG0025	NhaP-type Na H and K H
SGGB_RS09070	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SGGB_RS09075	COG1242	4 iron, 4 sulfur cluster binding
SGGB_RS09080	COG0671	phosphoesterase, PA-phosphatase related
SGGB_RS09090	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SGGB_RS09100	COG0300	oxidoreductase activity
SGGB_RS09105	COG0789	Transcriptional regulator
SGGB_RS09115	COG0569	domain protein
SGGB_RS09120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SGGB_RS09125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SGGB_RS09130	COG1187	pseudouridine synthase activity
SGGB_RS09145	COG0582	viral genome integration into host DNA
SGGB_RS09165	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SGGB_RS09170	COG3763	UPF0154 protein
SGGB_RS09190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGGB_RS09195	COG1254	Belongs to the acylphosphatase family
SGGB_RS09210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SGGB_RS09220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SGGB_RS09230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SGGB_RS09240	COG1484	DNA-dependent DNA replication
SGGB_RS09255	COG5002	protein histidine kinase activity
SGGB_RS09260	COG0745	RESPONSE REGULATOR receiver
SGGB_RS09270	COG0501	Belongs to the peptidase M48B family
SGGB_RS09275	COG1704	LemA family
SGGB_RS09285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SGGB_RS09290	COG0569	domain protein
SGGB_RS09300	COG1122	ATPase activity
SGGB_RS09320	COG1114	Component of the transport system for branched-chain amino acids
SGGB_RS09325	COG2910	NAD(P)H-binding
SGGB_RS09330	COG1959	2 iron, 2 sulfur cluster binding
SGGB_RS09355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGB_RS09360	COG1473	amidohydrolase
SGGB_RS09365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGB_RS09370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SGGB_RS09375	COG0217	transcriptional regulatory protein
SGGB_RS09380	COG2190	(PTS) system
SGGB_RS09380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS09380	COG1263	PTS System
SGGB_RS09385	COG2723	6-phospho-beta-galactosidase activity
SGGB_RS09390	COG1737	Transcriptional regulator
SGGB_RS09395	COG0702	epimerase
SGGB_RS09400	COG0789	Transcriptional regulator
SGGB_RS09405	COG1323	Belongs to the UPF0348 family
SGGB_RS09420	COG2226	methyltransferase
SGGB_RS09425	COG0799	negative regulation of ribosome biogenesis
SGGB_RS09430	COG1335	isochorismatase
SGGB_RS09435	COG1713	HD superfamily hydrolase involved in NAD metabolism
SGGB_RS09440	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SGGB_RS09445	COG1534	Rna-binding protein
SGGB_RS09450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SGGB_RS09460	COG2814	Major facilitator Superfamily
SGGB_RS09465	COG1846	Transcriptional regulator
SGGB_RS09480	COG0154	amidase activity
SGGB_RS09485	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGGB_RS09490	COG1335	isochorismatase
SGGB_RS09495	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SGGB_RS09500	COG0436	Aminotransferase
SGGB_RS09510	COG0589	response to stress
SGGB_RS09515	COG0561	phosphatase activity
SGGB_RS09520	COG0252	asparaginase activity
SGGB_RS09525	COG3655	Transcriptional regulator
SGGB_RS09540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SGGB_RS09555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SGGB_RS09560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SGGB_RS09570	COG1940	carbohydrate kinase activity
SGGB_RS09575	COG1263	PTS System
SGGB_RS09575	COG2190	(PTS) system
SGGB_RS09575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS09580	COG1621	beta-fructofuranosidase activity
SGGB_RS09585	COG1609	Transcriptional regulator
SGGB_RS09590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGGB_RS09600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SGGB_RS09615	COG2131	deaminase
SGGB_RS09620	COG0006	proline dipeptidase activity
SGGB_RS09640	COG0598	Magnesium transport protein CorA
SGGB_RS09655	COG3655	Transcriptional regulator
SGGB_RS09665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SGGB_RS09670	COG0629	single-stranded DNA binding
SGGB_RS09690	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SGGB_RS09700	COG3634	alkyl hydroperoxide reductase activity
SGGB_RS09705	COG0450	alkyl hydroperoxide reductase
SGGB_RS09710	COG1116	anion transmembrane transporter activity
SGGB_RS09715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGGB_RS09725	COG0318	PFAM AMP-dependent synthetase and ligase
SGGB_RS09740	COG1194	a g-specific adenine glycosylase
SGGB_RS09750	COG2223	nitrite transmembrane transporter activity
SGGB_RS09775	COG1063	alcohol dehydrogenase
SGGB_RS09780	COG3118	belongs to the thioredoxin family
SGGB_RS09785	COG0157	Belongs to the NadC ModD family
SGGB_RS09795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SGGB_RS09805	COG3842	ATPase activity
SGGB_RS09835	COG1902	pentaerythritol trinitrate reductase activity
SGGB_RS09845	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SGGB_RS09850	COG0681	Belongs to the peptidase S26 family
SGGB_RS09855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SGGB_RS09870	COG1882	Formate acetyltransferase
SGGB_RS09885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGGB_RS09905	COG5002	protein histidine kinase activity
SGGB_RS09920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGGB_RS09925	COG0581	inorganic phosphate transmembrane transporter activity
SGGB_RS09930	COG0573	inorganic phosphate transmembrane transporter activity
SGGB_RS09945	COG0789	Transcriptional regulator
SGGB_RS09960	COG2081	HI0933 family
SGGB_RS09990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SGGB_RS09995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SGGB_RS10005	COG3414	Phosphotransferase system galactitol-specific IIB component
SGGB_RS10010	COG3775	system Galactitol-specific IIC component
SGGB_RS10020	COG1349	DNA-binding transcription factor activity
SGGB_RS10035	COG0456	acetyltransferase
SGGB_RS10040	COG1214	PFAM Peptidase M22, glycoprotease
SGGB_RS10045	COG5503	Protein of unknown function (DUF1447)
SGGB_RS10055	COG3942	CHAP domain
SGGB_RS10060	COG0493	'glutamate synthase
SGGB_RS10065	COG0069	glutamate synthase activity
SGGB_RS10065	COG0067	glutamate synthase
SGGB_RS10065	COG0070	glutamate synthase
SGGB_RS10070	COG0174	glutamine synthetase
SGGB_RS10075	COG0789	Transcriptional regulator
SGGB_RS10085	COG0126	phosphoglycerate kinase activity
SGGB_RS10095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGGB_RS10110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SGGB_RS10130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SGGB_RS10155	COG3290	protein histidine kinase activity
SGGB_RS10240	COG2274	protein secretion by the type I secretion system
SGGB_RS10250	COG1266	CAAX protease self-immunity
SGGB_RS10275	COG0084	hydrolase, TatD family'
SGGB_RS10295	COG2217	Heavy metal translocating P-type atpase
SGGB_RS10325	COG2226	methyltransferase
SGGB_RS10330	COG1132	(ABC) transporter
SGGB_RS10355	COG0281	malic enzyme
SGGB_RS10360	COG0583	DNA-binding transcription factor activity
SGGB_RS10375	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SGGB_RS10380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGGB_RS10385	COG1696	Membrane protein involved in D-alanine export
SGGB_RS10405	COG1394	ATPase activity, coupled to movement of substances
SGGB_RS10410	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
SGGB_RS10420	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
SGGB_RS10425	COG1527	subunit (C
SGGB_RS10435	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGGB_RS10440	COG1269	ATP hydrolysis coupled proton transport
SGGB_RS10485	COG1131	(ABC) transporter
SGGB_RS10500	COG0594	ribonuclease P activity
SGGB_RS10515	COG2211	Major facilitator Superfamily
SGGB_RS10525	COG2807	transmembrane transport
SGGB_RS10530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SGGB_RS10550	COG0756	dUTP diphosphatase activity
SGGB_RS10575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SGGB_RS10580	COG0457	Tetratricopeptide repeat
SGGB_RS10580	COG0705	Rhomboid family
SGGB_RS10585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SGGB_RS10595	COG2171	N-acyltransferase activity
SGGB_RS10600	COG0166	Belongs to the GPI family
SGGB_RS10610	COG1234	tRNA 3'-trailer cleavage
SGGB_RS10615	COG1268	BioY protein
SGGB_RS10625	COG0343	queuine tRNA-ribosyltransferase activity
SGGB_RS10640	COG3479	Phenolic acid decarboxylase
SGGB_RS10645	COG1695	Transcriptional regulator
SGGB_RS10650	COG1832	CoA-binding protein
SGGB_RS10655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGGB_RS10655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGGB_RS10665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SGGB_RS10680	COG3711	transcriptional antiterminator
SGGB_RS10680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGB_RS10685	COG0800	Aldolase
SGGB_RS10690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGGB_RS10725	COG3623	hexulose-6-phosphate isomerase
SGGB_RS10735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGB_RS10745	COG3037	sugar-specific permease SgaT UlaA
SGGB_RS10755	COG1979	alcohol dehydrogenase
SGGB_RS10760	COG1464	Belongs to the NlpA lipoprotein family
SGGB_RS10765	COG2011	ABC-type metal ion transport system permease component
SGGB_RS10770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGGB_RS10780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SGGB_RS10785	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGGB_RS10785	COG2918	glutathione biosynthetic process
SGGB_RS10855	COG0582	viral genome integration into host DNA
SGGB_RS10885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGGB_RS10910	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SGGB_RS10915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SGGB_RS10920	COG0542	response to heat
SGGB_RS10925	COG4463	regulation of RNA biosynthetic process
SGGB_RS10945	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SGGB_RS10965	COG3764	Sortase (surface protein transpeptidase)
SGGB_RS11020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGGB_RS11070	COG0542	response to heat
SGGB_RS11075	COG0551	DNA topoisomerase type I activity
SGGB_RS11075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SGGB_RS11200	COG0270	DNA (cytosine-5-)-methyltransferase activity
SGGB_RS11210	COG1619	proteins homologs of microcin C7 resistance protein MccF
SGGB_RS11215	COG1396	sequence-specific DNA binding
SGGB_RS11220	COG3590	peptidase
SGGB_RS11230	COG0366	Alpha amylase catalytic
SGGB_RS11235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGB_RS11235	COG1263	PTS System
SGGB_RS11240	COG2188	Transcriptional regulator
SGGB_RS11265	COG2255	four-way junction helicase activity
SGGB_RS11270	COG0602	queuosine metabolic process
SGGB_RS11300	COG4472	Bacterial protein of unknown function (DUF965)
SGGB_RS11305	COG1393	Belongs to the ArsC family
SGGB_RS11315	COG1546	Belongs to the CinA family
SGGB_RS11315	COG1058	Belongs to the CinA family
SGGB_RS11385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGGB_RS11390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGGB_RS11415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SGGB_RS11460	COG1674	ftsk spoiiie
SGGB_RS11480	COG0582	viral genome integration into host DNA
SGGB_RS11515	COG3759	membrane
SGGB_RS11520	COG1511	domain protein
SGGB_RS11525	COG1309	transcriptional regulator
SGGB_RS11535	COG4466	Protein conserved in bacteria
SGGB_RS11540	COG0305	Participates in initiation and elongation during chromosome replication
SGGB_RS11555	COG0445	tRNA wobble uridine modification
SGGB_RS11565	COG0482	sulfurtransferase activity
SGGB_RS11570	COG1760	l-serine dehydratase
SGGB_RS11575	COG1760	l-serine dehydratase
SGGB_RS11580	COG0546	phosphoglycolate phosphatase activity
SGGB_RS11585	COG0741	lytic transglycosylase activity
SGGB_RS11600	COG1122	ATPase activity
SGGB_RS11605	COG1122	ATPase activity
SGGB_RS11610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SGGB_RS11620	COG0612	Peptidase, M16
SGGB_RS11625	COG0612	Peptidase, M16
SGGB_RS11635	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SGGB_RS11645	COG0516	GMP reductase activity
SGGB_RS11645	COG0517	IMP dehydrogenase activity
SGGB_RS11655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGGB_RS11660	COG0488	(ABC) transporter
SGGB_RS11690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGGB_RS11695	COG1475	DNA binding