locus-tag	class	description
SGGBAA2069_RS00010	COG0592	DNA-directed DNA polymerase activity
SGGBAA2069_RS00025	COG0012	GTP binding
SGGBAA2069_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SGGBAA2069_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SGGBAA2069_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SGGBAA2069_RS00250	COG1792	Involved in formation and maintenance of cell shape
SGGBAA2069_RS00260	COG3942	CHAP domain
SGGBAA2069_RS00270	COG0436	Aminotransferase
SGGBAA2069_RS00280	COG0416	fatty acid biosynthetic process
SGGBAA2069_RS00285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGGBAA2069_RS00290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SGGBAA2069_RS00295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGGBAA2069_RS00305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SGGBAA2069_RS00310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SGGBAA2069_RS00325	COG0151	Belongs to the GarS family
SGGBAA2069_RS00330	COG1683	Conserved Protein
SGGBAA2069_RS00335	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SGGBAA2069_RS00350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SGGBAA2069_RS00360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGGBAA2069_RS00385	COG2409	Drug exporters of the RND superfamily
SGGBAA2069_RS00395	COG2197	response regulator
SGGBAA2069_RS00400	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS00410	COG0051	transcription antitermination factor activity, RNA binding
SGGBAA2069_RS00420	COG0088	Forms part of the polypeptide exit tunnel
SGGBAA2069_RS00425	COG0089	rRNA binding
SGGBAA2069_RS00455	COG0255	Belongs to the universal ribosomal protein uL29 family
SGGBAA2069_RS00470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SGGBAA2069_RS00480	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SGGBAA2069_RS00500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SGGBAA2069_RS00505	COG1841	ribosomal large subunit assembly
SGGBAA2069_RS00515	COG0201	protein transport
SGGBAA2069_RS00520	COG0563	adenylate kinase activity
SGGBAA2069_RS00530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SGGBAA2069_RS00535	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SGGBAA2069_RS00540	COG0202	RNA polymerase activity
SGGBAA2069_RS00545	COG0203	ribosomal protein L17
SGGBAA2069_RS00640	COG0582	viral genome integration into host DNA
SGGBAA2069_RS00675	COG1131	(ABC) transporter
SGGBAA2069_RS00710	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SGGBAA2069_RS00720	COG1121	(ABC) transporter
SGGBAA2069_RS00725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGGBAA2069_RS00755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SGGBAA2069_RS00760	COG1459	type II secretion system
SGGBAA2069_RS00765	COG4537	Required for transformation and DNA binding
SGGBAA2069_RS00815	COG1266	CAAX protease self-immunity
SGGBAA2069_RS00820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SGGBAA2069_RS00825	COG1363	Peptidase, m42
SGGBAA2069_RS00830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SGGBAA2069_RS00835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGGBAA2069_RS00850	COG2391	methyltransferase activity
SGGBAA2069_RS00855	COG0425	Belongs to the sulfur carrier protein TusA family
SGGBAA2069_RS00860	COG0561	phosphatase activity
SGGBAA2069_RS00865	COG5492	domain, Protein
SGGBAA2069_RS00865	COG3583	domain protein
SGGBAA2069_RS00865	COG1621	beta-fructofuranosidase activity
SGGBAA2069_RS00875	COG4585	Histidine kinase
SGGBAA2069_RS00880	COG2197	response regulator
SGGBAA2069_RS00900	COG3715	PTS system
SGGBAA2069_RS00905	COG3716	PTS system mannose fructose sorbose family IID component
SGGBAA2069_RS00915	COG4120	Belongs to the binding-protein-dependent transport system permease family
SGGBAA2069_RS00920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGGBAA2069_RS00935	COG1396	sequence-specific DNA binding
SGGBAA2069_RS00945	COG0564	pseudouridine synthase activity
SGGBAA2069_RS00955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGGBAA2069_RS00975	COG4667	esterase of the alpha-beta hydrolase superfamily
SGGBAA2069_RS00985	COG2017	converts alpha-aldose to the beta-anomer
SGGBAA2069_RS00995	COG2249	NAD(P)H dehydrogenase (quinone) activity
SGGBAA2069_RS01010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SGGBAA2069_RS01035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SGGBAA2069_RS01040	COG1609	Transcriptional regulator
SGGBAA2069_RS01045	COG2190	(PTS) system
SGGBAA2069_RS01045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGBAA2069_RS01045	COG1263	PTS System
SGGBAA2069_RS01055	COG1363	Peptidase, m42
SGGBAA2069_RS01065	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGBAA2069_RS01070	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGGBAA2069_RS01075	COG2723	6-phospho-beta-galactosidase activity
SGGBAA2069_RS01080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGBAA2069_RS01085	COG2188	Transcriptional regulator
SGGBAA2069_RS01090	COG1482	cell wall glycoprotein biosynthetic process
SGGBAA2069_RS01100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SGGBAA2069_RS01105	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SGGBAA2069_RS01115	COG1653	transport
SGGBAA2069_RS01120	COG1175	transmembrane transport
SGGBAA2069_RS01125	COG0395	ABC-type sugar transport system, permease component
SGGBAA2069_RS01140	COG2188	Transcriptional regulator
SGGBAA2069_RS01145	COG1940	carbohydrate kinase activity
SGGBAA2069_RS01175	COG3842	ATPase activity
SGGBAA2069_RS01215	COG3775	system Galactitol-specific IIC component
SGGBAA2069_RS01225	COG3711	transcriptional antiterminator
SGGBAA2069_RS01230	COG2723	6-phospho-beta-galactosidase activity
SGGBAA2069_RS01235	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGGBAA2069_RS01240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGBAA2069_RS01240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGBAA2069_RS01245	COG3867	Arabinogalactan endo-beta-1,4-galactanase
SGGBAA2069_RS01250	COG2207	Transcriptional regulator
SGGBAA2069_RS01255	COG3345	alpha-galactosidase
SGGBAA2069_RS01260	COG1653	transport
SGGBAA2069_RS01265	COG1175	transmembrane transport
SGGBAA2069_RS01270	COG0395	ABC-type sugar transport system, permease component
SGGBAA2069_RS01275	COG0366	Alpha amylase catalytic
SGGBAA2069_RS01280	COG0366	Alpha amylase catalytic
SGGBAA2069_RS01285	COG1609	Transcriptional regulator
SGGBAA2069_RS01290	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SGGBAA2069_RS01295	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SGGBAA2069_RS01300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGGBAA2069_RS01310	COG1862	Preprotein translocase
SGGBAA2069_RS01315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGGBAA2069_RS01320	COG4589	Belongs to the CDS family
SGGBAA2069_RS01355	COG0242	peptide deformylase activity
SGGBAA2069_RS01375	COG0346	lactoylglutathione lyase activity
SGGBAA2069_RS01380	COG0561	phosphatase activity
SGGBAA2069_RS01390	COG1454	alcohol dehydrogenase
SGGBAA2069_RS01390	COG1012	belongs to the aldehyde dehydrogenase family
SGGBAA2069_RS01405	COG1185	polyribonucleotide nucleotidyltransferase activity
SGGBAA2069_RS01425	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SGGBAA2069_RS01455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SGGBAA2069_RS01485	COG2801	Transposase and inactivated derivatives
SGGBAA2069_RS01575	COG3830	Belongs to the UPF0237 family
SGGBAA2069_RS01580	COG2848	UPF0210 protein
SGGBAA2069_RS01585	COG0588	phosphoglycerate mutase activity
SGGBAA2069_RS01595	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGGBAA2069_RS01610	COG0443	Heat shock 70 kDa protein
SGGBAA2069_RS01630	COG0351	phosphomethylpyrimidine kinase
SGGBAA2069_RS01630	COG0352	thiamine-phosphate diphosphorylase activity
SGGBAA2069_RS01645	COG0668	transmembrane transport
SGGBAA2069_RS01660	COG0504	CTP synthase activity
SGGBAA2069_RS01675	COG0191	fructose-bisphosphate aldolase activity
SGGBAA2069_RS01685	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SGGBAA2069_RS01695	COG1461	Dihydroxyacetone kinase
SGGBAA2069_RS01700	COG0129	dihydroxy-acid dehydratase activity
SGGBAA2069_RS01705	COG0028	Belongs to the TPP enzyme family
SGGBAA2069_RS01710	COG0440	acetolactate synthase activity
SGGBAA2069_RS01715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SGGBAA2069_RS01720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SGGBAA2069_RS01735	COG1126	abc transporter atp-binding protein
SGGBAA2069_RS01740	COG0765	amino acid transport
SGGBAA2069_RS01760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGGBAA2069_RS01770	COG0719	Fe-S assembly protein
SGGBAA2069_RS01775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGGBAA2069_RS01785	COG0719	Fe-S assembly protein
SGGBAA2069_RS01790	COG1686	Belongs to the peptidase S11 family
SGGBAA2069_RS01795	COG4166	transmembrane transport
SGGBAA2069_RS01800	COG0601	transmembrane transport
SGGBAA2069_RS01805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGGBAA2069_RS01810	COG0444	Belongs to the ABC transporter superfamily
SGGBAA2069_RS01815	COG4608	Belongs to the ABC transporter superfamily
SGGBAA2069_RS01915	COG2755	lipolytic protein G-D-S-L family
SGGBAA2069_RS01915	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SGGBAA2069_RS01920	COG0527	aspartate kinase activity
SGGBAA2069_RS01925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGGBAA2069_RS01930	COG1024	Enoyl-CoA hydratase
SGGBAA2069_RS01940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGGBAA2069_RS01950	COG2070	2-Nitropropane dioxygenase
SGGBAA2069_RS01955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SGGBAA2069_RS01960	COG1028	Short-chain dehydrogenase reductase Sdr
SGGBAA2069_RS01965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGGBAA2069_RS01980	COG0439	Biotin carboxylase
SGGBAA2069_RS01995	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SGGBAA2069_RS02005	COG3716	PTS system mannose fructose sorbose family IID component
SGGBAA2069_RS02010	COG3715	PTS system
SGGBAA2069_RS02020	COG0561	phosphatase activity
SGGBAA2069_RS02035	COG2252	PERMEase
SGGBAA2069_RS02040	COG0802	atpase or kinase
SGGBAA2069_RS02050	COG1316	TRANSCRIPTIONal
SGGBAA2069_RS02060	COG0537	adenosine 5'-monophosphoramidase activity
SGGBAA2069_RS02065	COG1131	(ABC) transporter
SGGBAA2069_RS02070	COG4473	ABC transporter
SGGBAA2069_RS02080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SGGBAA2069_RS02090	COG3300	MHYT domain
SGGBAA2069_RS02090	COG5001	Diguanylate cyclase
SGGBAA2069_RS02115	COG0195	Participates in both transcription termination and antitermination
SGGBAA2069_RS02120	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SGGBAA2069_RS02130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SGGBAA2069_RS02135	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SGGBAA2069_RS02145	COG2801	Transposase and inactivated derivatives
SGGBAA2069_RS02165	COG2217	Heavy metal translocating P-type atpase
SGGBAA2069_RS02175	COG2860	membrane
SGGBAA2069_RS02180	COG0561	phosphatase activity
SGGBAA2069_RS02190	COG1309	transcriptional regulator
SGGBAA2069_RS02215	COG1283	sodium-dependent phosphate transmembrane transporter activity
SGGBAA2069_RS02240	COG3711	transcriptional antiterminator
SGGBAA2069_RS02240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS02250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS02250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SGGBAA2069_RS02250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS02255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGBAA2069_RS02265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SGGBAA2069_RS02285	COG1131	(ABC) transporter
SGGBAA2069_RS02295	COG1263	PTS System
SGGBAA2069_RS02295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGBAA2069_RS02300	COG1737	Transcriptional regulator
SGGBAA2069_RS02305	COG2723	6-phospho-beta-galactosidase activity
SGGBAA2069_RS02310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SGGBAA2069_RS02315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SGGBAA2069_RS02330	COG0768	penicillin binding
SGGBAA2069_RS02335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGGBAA2069_RS02340	COG0513	Belongs to the DEAD box helicase family
SGGBAA2069_RS02355	COG1126	abc transporter atp-binding protein
SGGBAA2069_RS02370	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SGGBAA2069_RS02375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SGGBAA2069_RS02380	COG3579	cysteine-type endopeptidase activity
SGGBAA2069_RS02385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGGBAA2069_RS02390	COG3331	DNA recombination
SGGBAA2069_RS02400	COG3599	regulation of cell shape
SGGBAA2069_RS02405	COG0116	Belongs to the methyltransferase superfamily
SGGBAA2069_RS02420	COG1854	S-ribosylhomocysteine lyase activity
SGGBAA2069_RS02440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SGGBAA2069_RS02445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SGGBAA2069_RS02450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SGGBAA2069_RS02450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGGBAA2069_RS02470	COG4585	Histidine kinase
SGGBAA2069_RS02475	COG2197	response regulator
SGGBAA2069_RS02485	COG1098	S1 RNA binding domain
SGGBAA2069_RS02495	COG1739	Uncharacterized protein family UPF0029
SGGBAA2069_RS02500	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SGGBAA2069_RS02505	COG1040	competence protein
SGGBAA2069_RS02575	COG3557	Belongs to the UPF0374 family
SGGBAA2069_RS02580	COG2137	regulation of response to DNA damage stimulus
SGGBAA2069_RS02590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGGBAA2069_RS02620	COG1428	Deoxynucleoside kinase
SGGBAA2069_RS02645	COG0519	Catalyzes the synthesis of GMP from XMP
SGGBAA2069_RS02655	COG0525	valine-tRNA ligase activity
SGGBAA2069_RS02675	COG1309	transcriptional regulator
SGGBAA2069_RS02700	COG2801	Transposase and inactivated derivatives
SGGBAA2069_RS02715	COG0742	ribosomal rna small subunit methyltransferase
SGGBAA2069_RS02725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SGGBAA2069_RS02730	COG3480	Lon protease (S16) C-terminal proteolytic domain
SGGBAA2069_RS02740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SGGBAA2069_RS02750	COG0737	Belongs to the 5'-nucleotidase family
SGGBAA2069_RS02755	COG4470	Protein conserved in bacteria
SGGBAA2069_RS02770	COG1132	(ABC) transporter
SGGBAA2069_RS02775	COG1132	(ABC) transporter
SGGBAA2069_RS02780	COG1131	(ABC) transporter
SGGBAA2069_RS02790	COG4585	Histidine kinase
SGGBAA2069_RS02795	COG2197	response regulator
SGGBAA2069_RS02800	COG4842	Belongs to the WXG100 family
SGGBAA2069_RS02815	COG4499	WXG100 protein secretion system (Wss), protein YukC
SGGBAA2069_RS02820	COG1674	ftsk spoiiie
SGGBAA2069_RS02945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGGBAA2069_RS02950	COG0512	Glutamine amidotransferase of anthranilate synthase
SGGBAA2069_RS02960	COG0134	indole-3-glycerol-phosphate synthase activity
SGGBAA2069_RS02965	COG0135	phosphoribosylanthranilate isomerase activity
SGGBAA2069_RS02970	COG0133	tryptophan synthase activity
SGGBAA2069_RS02975	COG0159	tryptophan synthase activity
SGGBAA2069_RS02980	COG1914	H( )-stimulated, divalent metal cation uptake system
SGGBAA2069_RS02990	COG0783	Belongs to the Dps family
SGGBAA2069_RS03000	COG1940	carbohydrate kinase activity
SGGBAA2069_RS03005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SGGBAA2069_RS03030	COG2207	Transcriptional regulator
SGGBAA2069_RS03035	COG1217	gtp-binding protein TYPA
SGGBAA2069_RS03070	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SGGBAA2069_RS03075	COG1799	cell septum assembly
SGGBAA2069_RS03090	COG3599	regulation of cell shape
SGGBAA2069_RS03110	COG0542	response to heat
SGGBAA2069_RS03120	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SGGBAA2069_RS03125	COG4703	Protein of unknown function (DUF1797)
SGGBAA2069_RS03130	COG0765	amino acid transport
SGGBAA2069_RS03135	COG1126	abc transporter atp-binding protein
SGGBAA2069_RS03160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SGGBAA2069_RS03190	COG1376	ErfK ybiS ycfS ynhG family protein
SGGBAA2069_RS03210	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SGGBAA2069_RS03215	COG1438	arginine binding
SGGBAA2069_RS03220	COG0497	DNA recombination
SGGBAA2069_RS03225	COG1307	EDD domain protein, DegV family
SGGBAA2069_RS03230	COG2755	lipolytic protein G-D-S-L family
SGGBAA2069_RS03255	COG3104	oligopeptide transport
SGGBAA2069_RS03260	COG0167	dihydroorotate dehydrogenase activity
SGGBAA2069_RS03265	COG4221	oxidoreductase activity
SGGBAA2069_RS03265	COG3321	synthase
SGGBAA2069_RS03265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGGBAA2069_RS03265	COG0604	alcohol dehydrogenase
SGGBAA2069_RS03270	COG0640	Transcriptional regulator
SGGBAA2069_RS03275	COG2217	Heavy metal translocating P-type atpase
SGGBAA2069_RS03280	COG2076	Multidrug Resistance protein
SGGBAA2069_RS03305	COG1827	regulation of RNA biosynthetic process
SGGBAA2069_RS03315	COG0768	penicillin binding
SGGBAA2069_RS03320	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SGGBAA2069_RS03325	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGGBAA2069_RS03335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SGGBAA2069_RS03355	COG0513	Belongs to the DEAD box helicase family
SGGBAA2069_RS03365	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SGGBAA2069_RS03370	COG0204	Acyl-transferase
SGGBAA2069_RS03375	COG1596	polysaccharide export
SGGBAA2069_RS03375	COG1555	photosystem II stabilization
SGGBAA2069_RS03380	COG0658	competence protein
SGGBAA2069_RS03380	COG2333	competence protein COMEC
SGGBAA2069_RS03390	COG1598	PFAM Uncharacterised protein family UPF0150
SGGBAA2069_RS03405	COG1466	dna polymerase III delta subunit
SGGBAA2069_RS03410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SGGBAA2069_RS03415	COG0217	transcriptional regulatory protein
SGGBAA2069_RS03430	COG0363	glucosamine-6-phosphate deaminase activity
SGGBAA2069_RS03435	COG1187	pseudouridine synthase activity
SGGBAA2069_RS03455	COG0546	phosphoglycolate phosphatase activity
SGGBAA2069_RS03460	COG4122	O-methyltransferase activity
SGGBAA2069_RS03470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SGGBAA2069_RS03485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGGBAA2069_RS03490	COG0436	Aminotransferase
SGGBAA2069_RS03510	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SGGBAA2069_RS03515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SGGBAA2069_RS03520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGGBAA2069_RS03525	COG2249	NAD(P)H dehydrogenase (quinone) activity
SGGBAA2069_RS03530	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS03535	COG2249	NAD(P)H dehydrogenase (quinone) activity
SGGBAA2069_RS03545	COG0656	L-ascorbic acid biosynthetic process
SGGBAA2069_RS03550	COG1902	pentaerythritol trinitrate reductase activity
SGGBAA2069_RS03560	COG0789	Transcriptional regulator
SGGBAA2069_RS03570	COG1476	TRANSCRIPTIONal
SGGBAA2069_RS03580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGGBAA2069_RS03580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGGBAA2069_RS03585	COG0307	riboflavin synthase, alpha
SGGBAA2069_RS03590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGGBAA2069_RS03590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGGBAA2069_RS03610	COG0656	L-ascorbic acid biosynthetic process
SGGBAA2069_RS03615	COG0656	L-ascorbic acid biosynthetic process
SGGBAA2069_RS03630	COG3859	Proton-coupled thiamine transporter YuaJ
SGGBAA2069_RS03635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGGBAA2069_RS03640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGGBAA2069_RS03645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SGGBAA2069_RS03650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SGGBAA2069_RS03655	COG0372	Belongs to the citrate synthase family
SGGBAA2069_RS03675	COG1609	Transcriptional regulator
SGGBAA2069_RS03680	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SGGBAA2069_RS03685	COG0251	oxidation-reduction process
SGGBAA2069_RS03695	COG1309	transcriptional regulator
SGGBAA2069_RS03775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGGBAA2069_RS03780	COG1660	Displays ATPase and GTPase activities
SGGBAA2069_RS03810	COG1396	sequence-specific DNA binding
SGGBAA2069_RS03835	COG1388	LysM domain
SGGBAA2069_RS03835	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGGBAA2069_RS03890	COG4974	Belongs to the 'phage' integrase family
SGGBAA2069_RS03900	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SGGBAA2069_RS03920	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SGGBAA2069_RS03930	COG0513	Belongs to the DEAD box helicase family
SGGBAA2069_RS03945	COG1609	Transcriptional regulator
SGGBAA2069_RS03955	COG2182	Extracellular solute-binding protein
SGGBAA2069_RS03960	COG1175	transmembrane transport
SGGBAA2069_RS03965	COG3833	ABC-type maltose transport systems, permease component
SGGBAA2069_RS03990	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SGGBAA2069_RS03995	COG0066	3-isopropylmalate dehydratase activity
SGGBAA2069_RS04000	COG1956	GAF domain-containing protein
SGGBAA2069_RS04005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SGGBAA2069_RS04015	COG2801	Transposase and inactivated derivatives
SGGBAA2069_RS04025	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SGGBAA2069_RS04025	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SGGBAA2069_RS04030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SGGBAA2069_RS04045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGGBAA2069_RS04055	COG4109	DRTGG domain
SGGBAA2069_RS04060	COG0024	Methionine aminopeptidase
SGGBAA2069_RS04070	COG2246	polysaccharide biosynthetic process
SGGBAA2069_RS04075	COG4708	membrane
SGGBAA2069_RS04080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGGBAA2069_RS04085	COG1597	lipid kinase activity
SGGBAA2069_RS04090	COG1523	belongs to the glycosyl hydrolase 13 family
SGGBAA2069_RS04095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SGGBAA2069_RS04100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SGGBAA2069_RS04105	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SGGBAA2069_RS04110	COG0297	glycogen (starch) synthase activity
SGGBAA2069_RS04115	COG0058	SHG alpha-glucan phosphorylase activity
SGGBAA2069_RS04125	COG0356	it plays a direct role in the translocation of protons across the membrane
SGGBAA2069_RS04130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SGGBAA2069_RS04165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGGBAA2069_RS04180	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SGGBAA2069_RS04185	COG0456	acetyltransferase
SGGBAA2069_RS04200	COG1074	ATP-dependent DNA helicase activity
SGGBAA2069_RS04225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SGGBAA2069_RS04240	COG0300	oxidoreductase activity
SGGBAA2069_RS04245	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SGGBAA2069_RS04245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SGGBAA2069_RS04270	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SGGBAA2069_RS04310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SGGBAA2069_RS04315	COG2384	SAM-dependent methyltransferase
SGGBAA2069_RS04325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SGGBAA2069_RS04335	COG1088	dTDP-glucose 4,6-dehydratase activity
SGGBAA2069_RS04345	COG1051	belongs to the nudix hydrolase family
SGGBAA2069_RS04350	COG0628	permease
SGGBAA2069_RS04355	COG0457	Tetratricopeptide repeat
SGGBAA2069_RS04365	COG0640	Transcriptional regulator
SGGBAA2069_RS04370	COG1902	pentaerythritol trinitrate reductase activity
SGGBAA2069_RS04375	COG0028	Belongs to the TPP enzyme family
SGGBAA2069_RS04380	COG3527	Alpha-acetolactate decarboxylase
SGGBAA2069_RS04385	COG0531	amino acid
SGGBAA2069_RS04390	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SGGBAA2069_RS04395	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS04400	COG1126	abc transporter atp-binding protein
SGGBAA2069_RS04405	COG0765	amino acid transport
SGGBAA2069_RS04415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGGBAA2069_RS04420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGGBAA2069_RS04425	COG4187	Peptidase family M20/M25/M40
SGGBAA2069_RS04435	COG4120	Belongs to the binding-protein-dependent transport system permease family
SGGBAA2069_RS04440	COG3842	ATPase activity
SGGBAA2069_RS04495	COG0488	(ABC) transporter
SGGBAA2069_RS04500	COG1396	sequence-specific DNA binding
SGGBAA2069_RS04515	COG1132	(ABC) transporter
SGGBAA2069_RS04520	COG1132	(ABC) transporter
SGGBAA2069_RS04530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SGGBAA2069_RS04535	COG0022	dehydrogenase e1 component
SGGBAA2069_RS04535	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGGBAA2069_RS04550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGGBAA2069_RS04555	COG4605	iron ion homeostasis
SGGBAA2069_RS04560	COG4604	ABC transporter, ATP-binding protein
SGGBAA2069_RS04570	COG0697	spore germination
SGGBAA2069_RS04575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGGBAA2069_RS04580	COG0095	Lipoate-protein ligase
SGGBAA2069_RS04595	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS04605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SGGBAA2069_RS04635	COG2814	Major facilitator Superfamily
SGGBAA2069_RS04650	COG0477	Major facilitator Superfamily
SGGBAA2069_RS04655	COG0431	NADPH-dependent FMN reductase
SGGBAA2069_RS04655	COG1053	succinate dehydrogenase
SGGBAA2069_RS04655	COG3976	FMN-binding domain protein
SGGBAA2069_RS04665	COG0431	NADPH-dependent FMN reductase
SGGBAA2069_RS04665	COG3976	FMN-binding domain protein
SGGBAA2069_RS04665	COG1053	succinate dehydrogenase
SGGBAA2069_RS04670	COG3976	FMN-binding domain protein
SGGBAA2069_RS04670	COG1053	succinate dehydrogenase
SGGBAA2069_RS04670	COG0431	NADPH-dependent FMN reductase
SGGBAA2069_RS04680	COG1937	Protein conserved in bacteria
SGGBAA2069_RS04690	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGGBAA2069_RS04700	COG1418	mRNA catabolic process
SGGBAA2069_RS04720	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS04730	COG1028	Short-chain dehydrogenase reductase Sdr
SGGBAA2069_RS04740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SGGBAA2069_RS04745	COG0789	Transcriptional regulator
SGGBAA2069_RS04750	COG0656	L-ascorbic acid biosynthetic process
SGGBAA2069_RS04775	COG1011	Hydrolase
SGGBAA2069_RS04785	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS04790	COG2855	membrane
SGGBAA2069_RS04795	COG1012	belongs to the aldehyde dehydrogenase family
SGGBAA2069_RS04805	COG0322	excinuclease ABC activity
SGGBAA2069_RS04830	COG1573	uracil-dna glycosylase
SGGBAA2069_RS04855	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SGGBAA2069_RS04860	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SGGBAA2069_RS04890	COG1316	TRANSCRIPTIONal
SGGBAA2069_RS04910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGGBAA2069_RS04925	COG1442	glycosyl transferase family 8
SGGBAA2069_RS04925	COG1216	Glycosyl transferase, family 2
SGGBAA2069_RS04945	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SGGBAA2069_RS04955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGBAA2069_RS04955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGBAA2069_RS04955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS04960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGBAA2069_RS04965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGBAA2069_RS04965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS04965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGBAA2069_RS04970	COG0383	alpha-mannosidase activity
SGGBAA2069_RS04985	COG2801	Transposase and inactivated derivatives
SGGBAA2069_RS04995	COG0167	dihydroorotate dehydrogenase activity
SGGBAA2069_RS05000	COG0284	orotidine-5'-phosphate decarboxylase activity
SGGBAA2069_RS05015	COG1881	PFAM PEBP family protein
SGGBAA2069_RS05035	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SGGBAA2069_RS05040	COG0187	DNA topoisomerase II activity
SGGBAA2069_RS05050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGGBAA2069_RS05055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SGGBAA2069_RS05075	COG0539	negative regulation of cytoplasmic translation
SGGBAA2069_RS05085	COG1346	cytolysis
SGGBAA2069_RS05090	COG1380	Effector of murein hydrolase LrgA
SGGBAA2069_RS05105	COG1131	(ABC) transporter
SGGBAA2069_RS05110	COG1725	Transcriptional regulator
SGGBAA2069_RS05120	COG0205	6-phosphofructokinase activity
SGGBAA2069_RS05125	COG0469	pyruvate kinase activity
SGGBAA2069_RS05140	COG2213	PTS system mannitol-specific
SGGBAA2069_RS05145	COG3711	transcriptional antiterminator
SGGBAA2069_RS05150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS05155	COG0246	Mannitol dehydrogenase
SGGBAA2069_RS05160	COG2824	Alkylphosphonate utilization operon protein PhnA
SGGBAA2069_RS05165	COG0765	amino acid transport
SGGBAA2069_RS05170	COG1126	abc transporter atp-binding protein
SGGBAA2069_RS05175	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SGGBAA2069_RS05180	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SGGBAA2069_RS05185	COG1115	amino acid carrier protein
SGGBAA2069_RS05190	COG2723	6-phospho-beta-galactosidase activity
SGGBAA2069_RS05200	COG0406	alpha-ribazole phosphatase activity
SGGBAA2069_RS05210	COG0628	permease
SGGBAA2069_RS05215	COG1442	glycosyl transferase family 8
SGGBAA2069_RS05225	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SGGBAA2069_RS05235	COG1104	cysteine desulfurase activity
SGGBAA2069_RS05250	COG2357	RelA SpoT domain protein
SGGBAA2069_RS05260	COG0564	pseudouridine synthase activity
SGGBAA2069_RS05265	COG0280	phosphate acetyltransferase
SGGBAA2069_RS05270	COG4221	oxidoreductase activity
SGGBAA2069_RS05280	COG0561	phosphatase activity
SGGBAA2069_RS05285	COG2723	6-phospho-beta-galactosidase activity
SGGBAA2069_RS05290	COG1136	(ABC) transporter
SGGBAA2069_RS05295	COG0577	efflux transmembrane transporter activity
SGGBAA2069_RS05300	COG0516	GMP reductase activity
SGGBAA2069_RS05305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SGGBAA2069_RS05325	COG2233	PERMEase
SGGBAA2069_RS05355	COG2890	protein-(glutamine-N5) methyltransferase activity
SGGBAA2069_RS05360	COG0009	L-threonylcarbamoyladenylate synthase
SGGBAA2069_RS05385	COG1132	(ABC) transporter
SGGBAA2069_RS05405	COG3711	transcriptional antiterminator
SGGBAA2069_RS05420	COG2723	6-phospho-beta-galactosidase activity
SGGBAA2069_RS05425	COG0519	Catalyzes the synthesis of GMP from XMP
SGGBAA2069_RS05425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SGGBAA2069_RS05430	COG2189	Belongs to the N(4) N(6)-methyltransferase family
SGGBAA2069_RS05435	COG3421	Type III restriction
SGGBAA2069_RS05475	COG4106	trans-aconitate 2-methyltransferase activity
SGGBAA2069_RS05485	COG1819	glycosyl
SGGBAA2069_RS05490	COG1396	sequence-specific DNA binding
SGGBAA2069_RS05495	COG5263	repeat protein
SGGBAA2069_RS05495	COG0366	Alpha amylase catalytic
SGGBAA2069_RS05500	COG1396	sequence-specific DNA binding
SGGBAA2069_RS05505	COG5263	repeat protein
SGGBAA2069_RS05505	COG0366	Alpha amylase catalytic
SGGBAA2069_RS05515	COG0534	Mate efflux family protein
SGGBAA2069_RS05530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SGGBAA2069_RS05535	COG0210	DNA helicase
SGGBAA2069_RS05540	COG2188	Transcriptional regulator
SGGBAA2069_RS05570	COG1737	Transcriptional regulator
SGGBAA2069_RS05575	COG0673	inositol 2-dehydrogenase activity
SGGBAA2069_RS05585	COG0673	inositol 2-dehydrogenase activity
SGGBAA2069_RS05600	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SGGBAA2069_RS05605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SGGBAA2069_RS05615	COG1132	(ABC) transporter
SGGBAA2069_RS05630	COG1129	ABC transporter
SGGBAA2069_RS05635	COG4974	Belongs to the 'phage' integrase family
SGGBAA2069_RS05645	COG5002	protein histidine kinase activity
SGGBAA2069_RS05650	COG0745	RESPONSE REGULATOR receiver
SGGBAA2069_RS05655	COG0577	efflux transmembrane transporter activity
SGGBAA2069_RS05660	COG1136	(ABC) transporter
SGGBAA2069_RS05670	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SGGBAA2069_RS05690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SGGBAA2069_RS05695	COG0758	DNA mediated transformation
SGGBAA2069_RS05700	COG0110	maltose O-acetyltransferase activity
SGGBAA2069_RS05705	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SGGBAA2069_RS05710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SGGBAA2069_RS05755	COG1131	(ABC) transporter
SGGBAA2069_RS05760	COG0488	(ABC) transporter
SGGBAA2069_RS05775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGGBAA2069_RS05780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGGBAA2069_RS05785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SGGBAA2069_RS05790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SGGBAA2069_RS05825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SGGBAA2069_RS05830	COG4684	Psort location CytoplasmicMembrane, score
SGGBAA2069_RS05835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGGBAA2069_RS05850	COG0346	lactoylglutathione lyase activity
SGGBAA2069_RS05855	COG3764	Sortase (surface protein transpeptidase)
SGGBAA2069_RS05875	COG2801	Transposase and inactivated derivatives
SGGBAA2069_RS05885	COG1079	Belongs to the binding-protein-dependent transport system permease family
SGGBAA2069_RS05890	COG4603	Belongs to the binding-protein-dependent transport system permease family
SGGBAA2069_RS05895	COG3845	ABC transporter
SGGBAA2069_RS05900	COG1744	ABC transporter substrate-binding protein PnrA-like
SGGBAA2069_RS05905	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SGGBAA2069_RS05910	COG2813	Specifically methylates the guanine in position
SGGBAA2069_RS05915	COG1072	(Pantothenic acid kinase))
SGGBAA2069_RS05925	COG5002	protein histidine kinase activity
SGGBAA2069_RS05930	COG0745	RESPONSE REGULATOR receiver
SGGBAA2069_RS05940	COG0704	Plays a role in the regulation of phosphate uptake
SGGBAA2069_RS05945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGGBAA2069_RS05950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGGBAA2069_RS05955	COG0581	inorganic phosphate transmembrane transporter activity
SGGBAA2069_RS05960	COG0573	inorganic phosphate transmembrane transporter activity
SGGBAA2069_RS05980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGGBAA2069_RS06000	COG0519	Catalyzes the synthesis of GMP from XMP
SGGBAA2069_RS06005	COG0483	inositol monophosphate 1-phosphatase activity
SGGBAA2069_RS06010	COG4476	Belongs to the UPF0223 family
SGGBAA2069_RS06015	COG1393	Belongs to the ArsC family
SGGBAA2069_RS06020	COG0196	riboflavin kinase activity
SGGBAA2069_RS06025	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SGGBAA2069_RS06050	COG2801	Transposase and inactivated derivatives
SGGBAA2069_RS06065	COG1129	ABC transporter
SGGBAA2069_RS06080	COG1132	(ABC) transporter
SGGBAA2069_RS06085	COG4988	ABC transporter
SGGBAA2069_RS06115	COG2873	o-acetylhomoserine
SGGBAA2069_RS06125	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SGGBAA2069_RS06170	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SGGBAA2069_RS06180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGGBAA2069_RS06185	COG1115	amino acid carrier protein
SGGBAA2069_RS06210	COG0561	phosphatase activity
SGGBAA2069_RS06230	COG2814	Major facilitator Superfamily
SGGBAA2069_RS06245	COG0561	phosphatase activity
SGGBAA2069_RS06250	COG0561	phosphatase activity
SGGBAA2069_RS06255	COG0110	maltose O-acetyltransferase activity
SGGBAA2069_RS06265	COG1028	Short-chain dehydrogenase reductase Sdr
SGGBAA2069_RS06275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGBAA2069_RS06285	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGGBAA2069_RS06290	COG3711	transcriptional antiterminator
SGGBAA2069_RS06290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS06295	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGGBAA2069_RS06315	COG2723	6-phospho-beta-galactosidase activity
SGGBAA2069_RS06335	COG1263	PTS System
SGGBAA2069_RS06335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGBAA2069_RS06335	COG2190	(PTS) system
SGGBAA2069_RS06340	COG3711	transcriptional antiterminator
SGGBAA2069_RS06355	COG1177	transmembrane transport
SGGBAA2069_RS06360	COG1176	ABC-type spermidine putrescine transport system, permease component I
SGGBAA2069_RS06370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SGGBAA2069_RS06395	COG0285	dihydrofolate synthase activity
SGGBAA2069_RS06400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGBAA2069_RS06405	COG1126	abc transporter atp-binding protein
SGGBAA2069_RS06410	COG4215	(ABC) transporter
SGGBAA2069_RS06420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGGBAA2069_RS06440	COG0726	polysaccharide deacetylase
SGGBAA2069_RS06450	COG1309	transcriptional regulator
SGGBAA2069_RS06465	COG0222	ribosome binding
SGGBAA2069_RS06490	COG2040	homocysteine
SGGBAA2069_RS06495	COG0833	amino acid
SGGBAA2069_RS06515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SGGBAA2069_RS06520	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SGGBAA2069_RS06525	COG3425	synthase
SGGBAA2069_RS06540	COG1272	protein, Hemolysin III
SGGBAA2069_RS06545	COG1304	FMN binding
SGGBAA2069_RS06560	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SGGBAA2069_RS06565	COG0435	Glutathione S-transferase
SGGBAA2069_RS06570	COG0435	Glutathione S-transferase
SGGBAA2069_RS06585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGBAA2069_RS06590	COG1126	abc transporter atp-binding protein
SGGBAA2069_RS06595	COG0765	amino acid transport
SGGBAA2069_RS06600	COG0765	amino acid transport
SGGBAA2069_RS06605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGBAA2069_RS06620	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS06625	COG0656	L-ascorbic acid biosynthetic process
SGGBAA2069_RS06635	COG0745	RESPONSE REGULATOR receiver
SGGBAA2069_RS06640	COG2357	RelA SpoT domain protein
SGGBAA2069_RS06675	COG1132	(ABC) transporter
SGGBAA2069_RS06690	COG0242	peptide deformylase activity
SGGBAA2069_RS06695	COG0456	acetyltransferase
SGGBAA2069_RS06700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SGGBAA2069_RS06710	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SGGBAA2069_RS06715	COG0602	queuosine metabolic process
SGGBAA2069_RS06720	COG0720	synthase
SGGBAA2069_RS06725	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SGGBAA2069_RS06730	COG1132	(ABC) transporter
SGGBAA2069_RS06740	COG0488	(ABC) transporter
SGGBAA2069_RS06745	COG0617	tRNA 3'-terminal CCA addition
SGGBAA2069_RS06765	COG1388	LysM domain
SGGBAA2069_RS06765	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGGBAA2069_RS06770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SGGBAA2069_RS06790	COG0667	Aldo Keto reductase
SGGBAA2069_RS06800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SGGBAA2069_RS06800	COG0646	methionine synthase
SGGBAA2069_RS06805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SGGBAA2069_RS06810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS06810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGBAA2069_RS06810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGGBAA2069_RS06815	COG1105	Belongs to the carbohydrate kinase PfkB family
SGGBAA2069_RS06820	COG1349	DNA-binding transcription factor activity
SGGBAA2069_RS06825	COG0492	ferredoxin-NADP+ reductase activity
SGGBAA2069_RS06830	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SGGBAA2069_RS06840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SGGBAA2069_RS06855	COG1837	Belongs to the UPF0109 family
SGGBAA2069_RS06875	COG2521	methyltransferase
SGGBAA2069_RS06875	COG2136	Putative SAM-dependent methyltransferase
SGGBAA2069_RS06885	COG0577	efflux transmembrane transporter activity
SGGBAA2069_RS06890	COG1136	(ABC) transporter
SGGBAA2069_RS06905	COG0505	Belongs to the CarA family
SGGBAA2069_RS06910	COG0540	Belongs to the ATCase OTCase family
SGGBAA2069_RS06925	COG0564	pseudouridine synthase activity
SGGBAA2069_RS06935	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS06940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SGGBAA2069_RS06965	COG0301	tRNA thio-modification
SGGBAA2069_RS06970	COG1104	cysteine desulfurase activity
SGGBAA2069_RS06980	COG0285	dihydrofolate synthase activity
SGGBAA2069_RS06995	COG0287	Prephenate dehydrogenase
SGGBAA2069_RS07005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGGBAA2069_RS07010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SGGBAA2069_RS07020	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SGGBAA2069_RS07025	COG1368	sulfuric ester hydrolase activity
SGGBAA2069_RS07030	COG3344	reverse transcriptase
SGGBAA2069_RS07035	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SGGBAA2069_RS07040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SGGBAA2069_RS07045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SGGBAA2069_RS07065	COG2195	Cleaves the N-terminal amino acid of tripeptides
SGGBAA2069_RS07080	COG3942	CHAP domain
SGGBAA2069_RS07090	COG0463	Glycosyl transferase, family 2
SGGBAA2069_RS07135	COG3843	relaxase mobilization nuclease domain protein
SGGBAA2069_RS07275	COG1368	sulfuric ester hydrolase activity
SGGBAA2069_RS07285	COG1216	Glycosyl transferase, family 2
SGGBAA2069_RS07285	COG1442	glycosyl transferase family 8
SGGBAA2069_RS07300	COG0463	Glycosyl transferase, family 2
SGGBAA2069_RS07310	COG1091	dTDP-4-dehydrorhamnose reductase activity
SGGBAA2069_RS07315	COG2151	metal-sulfur cluster biosynthetic enzyme
SGGBAA2069_RS07320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGGBAA2069_RS07325	COG0358	DNA primase activity
SGGBAA2069_RS07330	COG1970	mechanosensitive ion channel activity
SGGBAA2069_RS07345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGBAA2069_RS07350	COG0436	Aminotransferase
SGGBAA2069_RS07355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGBAA2069_RS07365	COG0058	SHG alpha-glucan phosphorylase activity
SGGBAA2069_RS07370	COG1640	4-alpha-glucanotransferase
SGGBAA2069_RS07375	COG1609	Transcriptional regulator
SGGBAA2069_RS07385	COG1175	transmembrane transport
SGGBAA2069_RS07390	COG3833	ABC-type maltose transport systems, permease component
SGGBAA2069_RS07395	COG2816	NAD+ diphosphatase activity
SGGBAA2069_RS07400	COG0556	nucleotide-excision repair
SGGBAA2069_RS07405	COG0765	amino acid transport
SGGBAA2069_RS07410	COG1126	abc transporter atp-binding protein
SGGBAA2069_RS07415	COG0488	(ABC) transporter
SGGBAA2069_RS07430	COG1187	pseudouridine synthase activity
SGGBAA2069_RS07435	COG4166	transmembrane transport
SGGBAA2069_RS07440	COG4166	transmembrane transport
SGGBAA2069_RS07455	COG0659	secondary active sulfate transmembrane transporter activity
SGGBAA2069_RS07475	COG0590	tRNA wobble adenosine to inosine editing
SGGBAA2069_RS07485	COG0456	acetyltransferase
SGGBAA2069_RS07530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGGBAA2069_RS07550	COG1316	TRANSCRIPTIONal
SGGBAA2069_RS07555	COG0077	Prephenate dehydratase
SGGBAA2069_RS07560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SGGBAA2069_RS07565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGGBAA2069_RS07570	COG0481	GTPase activity
SGGBAA2069_RS07600	COG1518	maintenance of DNA repeat elements
SGGBAA2069_RS07605	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
SGGBAA2069_RS07620	COG0647	UMP catabolic process
SGGBAA2069_RS07625	COG1051	belongs to the nudix hydrolase family
SGGBAA2069_RS07635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SGGBAA2069_RS07640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGGBAA2069_RS07650	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SGGBAA2069_RS07655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SGGBAA2069_RS07660	COG3442	glutamine amidotransferase
SGGBAA2069_RS07665	COG0148	phosphopyruvate hydratase activity
SGGBAA2069_RS07685	COG1523	belongs to the glycosyl hydrolase 13 family
SGGBAA2069_RS07700	COG0107	imidazoleglycerol-phosphate synthase activity
SGGBAA2069_RS07710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SGGBAA2069_RS07720	COG0560	Phosphoserine phosphatase
SGGBAA2069_RS07735	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SGGBAA2069_RS07755	COG0187	DNA topoisomerase II activity
SGGBAA2069_RS07765	COG0772	Belongs to the SEDS family
SGGBAA2069_RS07780	COG0038	chloride channel
SGGBAA2069_RS07785	COG0287	Prephenate dehydrogenase
SGGBAA2069_RS07785	COG1605	Chorismate mutase
SGGBAA2069_RS07800	COG0716	FMN binding
SGGBAA2069_RS07815	COG0017	Asparaginyl-tRNA synthetase
SGGBAA2069_RS07825	COG0436	Aminotransferase
SGGBAA2069_RS07835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SGGBAA2069_RS07835	COG1199	ATP-dependent helicase activity
SGGBAA2069_RS07850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SGGBAA2069_RS07870	COG2177	Part of the ABC transporter FtsEX involved in
SGGBAA2069_RS07875	COG2884	Cell division ATP-binding protein ftsE
SGGBAA2069_RS07880	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SGGBAA2069_RS07885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGGBAA2069_RS07910	COG1078	dGTPase activity
SGGBAA2069_RS07935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SGGBAA2069_RS07950	COG0772	Belongs to the SEDS family
SGGBAA2069_RS07965	COG0386	Belongs to the glutathione peroxidase family
SGGBAA2069_RS07985	COG0588	phosphoglycerate mutase activity
SGGBAA2069_RS08020	COG1268	BioY protein
SGGBAA2069_RS08025	COG4443	Transcriptional Coactivator p15 (PC4)
SGGBAA2069_RS08035	COG0826	peptidase U32
SGGBAA2069_RS08080	COG2183	response to ionizing radiation
SGGBAA2069_RS08090	COG0701	Predicted permease
SGGBAA2069_RS08095	COG3689	TIGRFAM TIGR03943 family protein
SGGBAA2069_RS08100	COG0604	alcohol dehydrogenase
SGGBAA2069_RS08100	COG3321	synthase
SGGBAA2069_RS08105	COG0789	Transcriptional regulator
SGGBAA2069_RS08115	COG0552	protein localization to endoplasmic reticulum
SGGBAA2069_RS08120	COG0561	phosphatase activity
SGGBAA2069_RS08125	COG0561	phosphatase activity
SGGBAA2069_RS08135	COG1196	nuclear chromosome segregation
SGGBAA2069_RS08145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SGGBAA2069_RS08150	COG5002	protein histidine kinase activity
SGGBAA2069_RS08155	COG0745	RESPONSE REGULATOR receiver
SGGBAA2069_RS08160	COG1126	abc transporter atp-binding protein
SGGBAA2069_RS08165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGBAA2069_RS08170	COG0765	amino acid transport
SGGBAA2069_RS08175	COG0765	amino acid transport
SGGBAA2069_RS08200	COG0745	RESPONSE REGULATOR receiver
SGGBAA2069_RS08225	COG4716	Myosin-crossreactive antigen
SGGBAA2069_RS08290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SGGBAA2069_RS08295	COG0438	transferase activity, transferring glycosyl groups
SGGBAA2069_RS08305	COG1609	Transcriptional regulator
SGGBAA2069_RS08310	COG0006	proline dipeptidase activity
SGGBAA2069_RS08320	COG2816	NAD+ diphosphatase activity
SGGBAA2069_RS08335	COG1263	PTS System
SGGBAA2069_RS08335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGBAA2069_RS08335	COG2190	(PTS) system
SGGBAA2069_RS08355	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS08370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGGBAA2069_RS08395	COG0667	Aldo Keto reductase
SGGBAA2069_RS08405	COG2211	Major facilitator Superfamily
SGGBAA2069_RS08415	COG3394	polysaccharide catabolic process
SGGBAA2069_RS08420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGBAA2069_RS08420	COG2190	(PTS) system
SGGBAA2069_RS08420	COG1263	PTS System
SGGBAA2069_RS08435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGBAA2069_RS08435	COG2190	(PTS) system
SGGBAA2069_RS08435	COG1263	PTS System
SGGBAA2069_RS08455	COG0163	prenyltransferase activity
SGGBAA2069_RS08460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SGGBAA2069_RS08465	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS08470	COG1811	Na channel or pump
SGGBAA2069_RS08485	COG0778	Nitroreductase
SGGBAA2069_RS08490	COG2723	6-phospho-beta-galactosidase activity
SGGBAA2069_RS08495	COG1263	PTS System
SGGBAA2069_RS08495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGBAA2069_RS08495	COG2190	(PTS) system
SGGBAA2069_RS08510	COG0557	exoribonuclease II activity
SGGBAA2069_RS08520	COG2814	Major facilitator Superfamily
SGGBAA2069_RS08525	COG0237	dephospho-CoA kinase activity
SGGBAA2069_RS08530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGGBAA2069_RS08540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SGGBAA2069_RS08545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SGGBAA2069_RS08550	COG0366	Alpha amylase catalytic
SGGBAA2069_RS08565	COG1702	phosphate starvation-inducible protein PhoH
SGGBAA2069_RS08575	COG4479	Belongs to the UPF0346 family
SGGBAA2069_RS08585	COG2996	Protein conserved in bacteria
SGGBAA2069_RS08620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SGGBAA2069_RS08645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SGGBAA2069_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
SGGBAA2069_RS08675	COG1695	Transcriptional regulator
SGGBAA2069_RS08690	COG0534	Mate efflux family protein
SGGBAA2069_RS08700	COG0708	Exodeoxyribonuclease III
SGGBAA2069_RS08705	COG2814	Major facilitator Superfamily
SGGBAA2069_RS08725	COG0656	L-ascorbic acid biosynthetic process
SGGBAA2069_RS08735	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS08740	COG1393	Belongs to the ArsC family
SGGBAA2069_RS08745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGGBAA2069_RS08755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGGBAA2069_RS08780	COG0004	ammonium transporteR
SGGBAA2069_RS08795	COG1774	PSP1 C-terminal conserved region
SGGBAA2069_RS08800	COG0470	DNA polymerase III
SGGBAA2069_RS08810	COG0517	IMP dehydrogenase activity
SGGBAA2069_RS08810	COG1227	inorganic diphosphatase activity
SGGBAA2069_RS08860	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS08865	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SGGBAA2069_RS08870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SGGBAA2069_RS08875	COG0626	cystathionine gamma-synthase activity
SGGBAA2069_RS08880	COG2244	polysaccharide biosynthetic process
SGGBAA2069_RS08890	COG1120	ATPase activity
SGGBAA2069_RS08895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGGBAA2069_RS08900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGGBAA2069_RS08905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGGBAA2069_RS08925	COG1227	inorganic diphosphatase activity
SGGBAA2069_RS08935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SGGBAA2069_RS08940	COG1253	flavin adenine dinucleotide binding
SGGBAA2069_RS08945	COG1119	ATPase activity
SGGBAA2069_RS08950	COG0025	NhaP-type Na H and K H
SGGBAA2069_RS08960	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SGGBAA2069_RS08965	COG1242	4 iron, 4 sulfur cluster binding
SGGBAA2069_RS08970	COG0671	phosphoesterase, PA-phosphatase related
SGGBAA2069_RS08980	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SGGBAA2069_RS08990	COG0300	oxidoreductase activity
SGGBAA2069_RS08995	COG0789	Transcriptional regulator
SGGBAA2069_RS09000	COG0531	amino acid
SGGBAA2069_RS09005	COG0569	domain protein
SGGBAA2069_RS09010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SGGBAA2069_RS09015	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SGGBAA2069_RS09020	COG1187	pseudouridine synthase activity
SGGBAA2069_RS09035	COG0582	viral genome integration into host DNA
SGGBAA2069_RS09055	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SGGBAA2069_RS09060	COG3763	UPF0154 protein
SGGBAA2069_RS09080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGGBAA2069_RS09085	COG1254	Belongs to the acylphosphatase family
SGGBAA2069_RS09100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SGGBAA2069_RS09110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SGGBAA2069_RS09120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SGGBAA2069_RS09130	COG1484	DNA-dependent DNA replication
SGGBAA2069_RS09145	COG5002	protein histidine kinase activity
SGGBAA2069_RS09150	COG0745	RESPONSE REGULATOR receiver
SGGBAA2069_RS09160	COG0501	Belongs to the peptidase M48B family
SGGBAA2069_RS09165	COG1704	LemA family
SGGBAA2069_RS09175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SGGBAA2069_RS09180	COG0569	domain protein
SGGBAA2069_RS09190	COG1122	ATPase activity
SGGBAA2069_RS09210	COG1114	Component of the transport system for branched-chain amino acids
SGGBAA2069_RS09220	COG2910	NAD(P)H-binding
SGGBAA2069_RS09225	COG1959	2 iron, 2 sulfur cluster binding
SGGBAA2069_RS09250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGBAA2069_RS09255	COG1473	amidohydrolase
SGGBAA2069_RS09260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGGBAA2069_RS09265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SGGBAA2069_RS09270	COG0217	transcriptional regulatory protein
SGGBAA2069_RS09300	COG2226	methyltransferase
SGGBAA2069_RS09305	COG0799	negative regulation of ribosome biogenesis
SGGBAA2069_RS09310	COG1335	isochorismatase
SGGBAA2069_RS09315	COG1713	HD superfamily hydrolase involved in NAD metabolism
SGGBAA2069_RS09320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SGGBAA2069_RS09325	COG1534	Rna-binding protein
SGGBAA2069_RS09330	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SGGBAA2069_RS09335	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SGGBAA2069_RS09340	COG2814	Major facilitator Superfamily
SGGBAA2069_RS09345	COG1846	Transcriptional regulator
SGGBAA2069_RS09360	COG0154	amidase activity
SGGBAA2069_RS09365	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGGBAA2069_RS09370	COG1335	isochorismatase
SGGBAA2069_RS09375	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SGGBAA2069_RS09380	COG0436	Aminotransferase
SGGBAA2069_RS09390	COG0589	response to stress
SGGBAA2069_RS09395	COG0561	phosphatase activity
SGGBAA2069_RS09400	COG0252	asparaginase activity
SGGBAA2069_RS09405	COG3655	Transcriptional regulator
SGGBAA2069_RS09420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SGGBAA2069_RS09435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SGGBAA2069_RS09440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SGGBAA2069_RS09450	COG1940	carbohydrate kinase activity
SGGBAA2069_RS09455	COG1263	PTS System
SGGBAA2069_RS09455	COG2190	(PTS) system
SGGBAA2069_RS09455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGBAA2069_RS09460	COG1621	beta-fructofuranosidase activity
SGGBAA2069_RS09465	COG1609	Transcriptional regulator
SGGBAA2069_RS09470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGGBAA2069_RS09480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SGGBAA2069_RS09495	COG2131	deaminase
SGGBAA2069_RS09500	COG0006	proline dipeptidase activity
SGGBAA2069_RS09510	COG0598	Magnesium transport protein CorA
SGGBAA2069_RS09525	COG3655	Transcriptional regulator
SGGBAA2069_RS09535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SGGBAA2069_RS09540	COG0629	single-stranded DNA binding
SGGBAA2069_RS09560	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SGGBAA2069_RS09570	COG3634	alkyl hydroperoxide reductase activity
SGGBAA2069_RS09575	COG0450	alkyl hydroperoxide reductase
SGGBAA2069_RS09580	COG1116	anion transmembrane transporter activity
SGGBAA2069_RS09585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGGBAA2069_RS09595	COG0318	PFAM AMP-dependent synthetase and ligase
SGGBAA2069_RS09610	COG1194	a g-specific adenine glycosylase
SGGBAA2069_RS09620	COG2223	nitrite transmembrane transporter activity
SGGBAA2069_RS09645	COG1063	alcohol dehydrogenase
SGGBAA2069_RS09650	COG3118	belongs to the thioredoxin family
SGGBAA2069_RS09660	COG0157	Belongs to the NadC ModD family
SGGBAA2069_RS09670	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SGGBAA2069_RS09700	COG1902	pentaerythritol trinitrate reductase activity
SGGBAA2069_RS09710	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SGGBAA2069_RS09715	COG0681	Belongs to the peptidase S26 family
SGGBAA2069_RS09720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SGGBAA2069_RS09735	COG1882	Formate acetyltransferase
SGGBAA2069_RS09750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGGBAA2069_RS09770	COG5002	protein histidine kinase activity
SGGBAA2069_RS09785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGGBAA2069_RS09790	COG0581	inorganic phosphate transmembrane transporter activity
SGGBAA2069_RS09795	COG0573	inorganic phosphate transmembrane transporter activity
SGGBAA2069_RS09815	COG0789	Transcriptional regulator
SGGBAA2069_RS09830	COG2081	HI0933 family
SGGBAA2069_RS09860	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SGGBAA2069_RS09865	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SGGBAA2069_RS09875	COG3414	Phosphotransferase system galactitol-specific IIB component
SGGBAA2069_RS09880	COG3775	system Galactitol-specific IIC component
SGGBAA2069_RS09890	COG1349	DNA-binding transcription factor activity
SGGBAA2069_RS09905	COG0456	acetyltransferase
SGGBAA2069_RS09910	COG1214	PFAM Peptidase M22, glycoprotease
SGGBAA2069_RS09915	COG5503	Protein of unknown function (DUF1447)
SGGBAA2069_RS09925	COG3942	CHAP domain
SGGBAA2069_RS09930	COG0493	'glutamate synthase
SGGBAA2069_RS09935	COG0070	glutamate synthase
SGGBAA2069_RS09935	COG0069	glutamate synthase activity
SGGBAA2069_RS09935	COG0067	glutamate synthase
SGGBAA2069_RS09940	COG0174	glutamine synthetase
SGGBAA2069_RS09945	COG0789	Transcriptional regulator
SGGBAA2069_RS09955	COG0126	phosphoglycerate kinase activity
SGGBAA2069_RS09965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGGBAA2069_RS09980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SGGBAA2069_RS10025	COG3290	protein histidine kinase activity
SGGBAA2069_RS10030	COG3279	Response regulator of the LytR AlgR family
SGGBAA2069_RS10075	COG0463	Glycosyl transferase, family 2
SGGBAA2069_RS10115	COG2274	protein secretion by the type I secretion system
SGGBAA2069_RS10125	COG1266	CAAX protease self-immunity
SGGBAA2069_RS10150	COG0084	hydrolase, TatD family'
SGGBAA2069_RS10170	COG2217	Heavy metal translocating P-type atpase
SGGBAA2069_RS10190	COG0681	Belongs to the peptidase S26 family
SGGBAA2069_RS10205	COG2226	methyltransferase
SGGBAA2069_RS10210	COG1132	(ABC) transporter
SGGBAA2069_RS10235	COG0281	malic enzyme
SGGBAA2069_RS10240	COG0583	DNA-binding transcription factor activity
SGGBAA2069_RS10255	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SGGBAA2069_RS10260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGGBAA2069_RS10265	COG1696	Membrane protein involved in D-alanine export
SGGBAA2069_RS10285	COG1394	ATPase activity, coupled to movement of substances
SGGBAA2069_RS10290	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
SGGBAA2069_RS10300	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
SGGBAA2069_RS10305	COG1527	subunit (C
SGGBAA2069_RS10315	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGGBAA2069_RS10320	COG1269	ATP hydrolysis coupled proton transport
SGGBAA2069_RS10360	COG3764	Sortase (surface protein transpeptidase)
SGGBAA2069_RS10385	COG3843	relaxase mobilization nuclease domain protein
SGGBAA2069_RS10545	COG1131	(ABC) transporter
SGGBAA2069_RS10560	COG0594	ribonuclease P activity
SGGBAA2069_RS10575	COG2211	Major facilitator Superfamily
SGGBAA2069_RS10585	COG2807	transmembrane transport
SGGBAA2069_RS10590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SGGBAA2069_RS10610	COG0756	dUTP diphosphatase activity
SGGBAA2069_RS10635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SGGBAA2069_RS10640	COG0705	Rhomboid family
SGGBAA2069_RS10640	COG0457	Tetratricopeptide repeat
SGGBAA2069_RS10645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SGGBAA2069_RS10655	COG2171	N-acyltransferase activity
SGGBAA2069_RS10660	COG0166	Belongs to the GPI family
SGGBAA2069_RS10670	COG1234	tRNA 3'-trailer cleavage
SGGBAA2069_RS10675	COG1268	BioY protein
SGGBAA2069_RS10685	COG0343	queuine tRNA-ribosyltransferase activity
SGGBAA2069_RS10700	COG3479	Phenolic acid decarboxylase
SGGBAA2069_RS10705	COG1695	Transcriptional regulator
SGGBAA2069_RS10710	COG1832	CoA-binding protein
SGGBAA2069_RS10715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGGBAA2069_RS10715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGGBAA2069_RS10725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SGGBAA2069_RS10740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS10740	COG3711	transcriptional antiterminator
SGGBAA2069_RS10745	COG0800	Aldolase
SGGBAA2069_RS10750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGGBAA2069_RS10785	COG3623	hexulose-6-phosphate isomerase
SGGBAA2069_RS10795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGGBAA2069_RS10805	COG3037	sugar-specific permease SgaT UlaA
SGGBAA2069_RS10815	COG1979	alcohol dehydrogenase
SGGBAA2069_RS10820	COG1464	Belongs to the NlpA lipoprotein family
SGGBAA2069_RS10825	COG2011	ABC-type metal ion transport system permease component
SGGBAA2069_RS10830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGGBAA2069_RS10840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SGGBAA2069_RS10845	COG2918	glutathione biosynthetic process
SGGBAA2069_RS10845	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGGBAA2069_RS10915	COG0582	viral genome integration into host DNA
SGGBAA2069_RS10945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGGBAA2069_RS10970	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SGGBAA2069_RS10975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SGGBAA2069_RS10980	COG0542	response to heat
SGGBAA2069_RS10985	COG4463	regulation of RNA biosynthetic process
SGGBAA2069_RS11005	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SGGBAA2069_RS11020	COG1619	proteins homologs of microcin C7 resistance protein MccF
SGGBAA2069_RS11025	COG1396	sequence-specific DNA binding
SGGBAA2069_RS11030	COG3590	peptidase
SGGBAA2069_RS11040	COG0366	Alpha amylase catalytic
SGGBAA2069_RS11045	COG1263	PTS System
SGGBAA2069_RS11045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGGBAA2069_RS11050	COG2188	Transcriptional regulator
SGGBAA2069_RS11075	COG2255	four-way junction helicase activity
SGGBAA2069_RS11080	COG0602	queuosine metabolic process
SGGBAA2069_RS11110	COG4472	Bacterial protein of unknown function (DUF965)
SGGBAA2069_RS11115	COG1393	Belongs to the ArsC family
SGGBAA2069_RS11125	COG1546	Belongs to the CinA family
SGGBAA2069_RS11125	COG1058	Belongs to the CinA family
SGGBAA2069_RS11195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGGBAA2069_RS11200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGGBAA2069_RS11225	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SGGBAA2069_RS11230	COG0582	viral genome integration into host DNA
SGGBAA2069_RS11250	COG3764	Sortase (surface protein transpeptidase)
SGGBAA2069_RS11265	COG0433	COG0433 Predicted ATPase
SGGBAA2069_RS11320	COG1674	ftsk spoiiie
SGGBAA2069_RS11495	COG1674	ftsk spoiiie
SGGBAA2069_RS11515	COG0582	viral genome integration into host DNA
SGGBAA2069_RS11550	COG3759	membrane
SGGBAA2069_RS11555	COG1511	domain protein
SGGBAA2069_RS11560	COG1309	transcriptional regulator
SGGBAA2069_RS11570	COG4466	Protein conserved in bacteria
SGGBAA2069_RS11575	COG0305	Participates in initiation and elongation during chromosome replication
SGGBAA2069_RS11590	COG0445	tRNA wobble uridine modification
SGGBAA2069_RS11600	COG0482	sulfurtransferase activity
SGGBAA2069_RS11605	COG1760	l-serine dehydratase
SGGBAA2069_RS11610	COG1760	l-serine dehydratase
SGGBAA2069_RS11615	COG0546	phosphoglycolate phosphatase activity
SGGBAA2069_RS11620	COG0741	lytic transglycosylase activity
SGGBAA2069_RS11635	COG1122	ATPase activity
SGGBAA2069_RS11640	COG1122	ATPase activity
SGGBAA2069_RS11645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SGGBAA2069_RS11655	COG0612	Peptidase, M16
SGGBAA2069_RS11660	COG0612	Peptidase, M16
SGGBAA2069_RS11670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SGGBAA2069_RS11680	COG0516	GMP reductase activity
SGGBAA2069_RS11680	COG0517	IMP dehydrogenase activity
SGGBAA2069_RS11690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGGBAA2069_RS11695	COG0488	(ABC) transporter
SGGBAA2069_RS11725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGGBAA2069_RS11730	COG1475	DNA binding