locus-tag	class	description
BTR42_RS00010	COG0592	DNA-directed DNA polymerase activity
BTR42_RS00025	COG0012	GTP binding
BTR42_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTR42_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BTR42_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTR42_RS00240	COG1792	Involved in formation and maintenance of cell shape
BTR42_RS00250	COG3942	CHAP domain
BTR42_RS00260	COG0436	Aminotransferase
BTR42_RS00270	COG0416	fatty acid biosynthetic process
BTR42_RS00275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTR42_RS00280	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BTR42_RS00285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTR42_RS00295	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BTR42_RS00300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTR42_RS00315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTR42_RS00340	COG2409	Drug exporters of the RND superfamily
BTR42_RS00350	COG2197	response regulator
BTR42_RS00355	COG0583	DNA-binding transcription factor activity
BTR42_RS00365	COG0051	transcription antitermination factor activity, RNA binding
BTR42_RS00375	COG0088	Forms part of the polypeptide exit tunnel
BTR42_RS00380	COG0089	rRNA binding
BTR42_RS00410	COG0255	Belongs to the universal ribosomal protein uL29 family
BTR42_RS00425	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BTR42_RS00435	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BTR42_RS00455	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BTR42_RS00460	COG1841	ribosomal large subunit assembly
BTR42_RS00470	COG0201	protein transport
BTR42_RS00475	COG0563	adenylate kinase activity
BTR42_RS00490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BTR42_RS00495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BTR42_RS00500	COG0202	RNA polymerase activity
BTR42_RS00505	COG0203	ribosomal protein L17
BTR42_RS00590	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BTR42_RS00600	COG1121	(ABC) transporter
BTR42_RS00605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTR42_RS00635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTR42_RS00640	COG1459	type II secretion system
BTR42_RS00645	COG4537	Required for transformation and DNA binding
BTR42_RS00695	COG1266	CAAX protease self-immunity
BTR42_RS00705	COG0151	Belongs to the GarS family
BTR42_RS00710	COG1683	Conserved Protein
BTR42_RS00715	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTR42_RS00730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTR42_RS00740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTR42_RS00745	COG1363	Peptidase, m42
BTR42_RS00760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTR42_RS00765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTR42_RS00780	COG2391	methyltransferase activity
BTR42_RS00785	COG0425	Belongs to the sulfur carrier protein TusA family
BTR42_RS00790	COG0561	phosphatase activity
BTR42_RS00810	COG4585	Histidine kinase
BTR42_RS00815	COG2197	response regulator
BTR42_RS00835	COG3715	PTS system
BTR42_RS00840	COG3716	PTS system mannose fructose sorbose family IID component
BTR42_RS00855	COG4120	Belongs to the binding-protein-dependent transport system permease family
BTR42_RS00860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTR42_RS00875	COG1396	sequence-specific DNA binding
BTR42_RS00890	COG0564	pseudouridine synthase activity
BTR42_RS00900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTR42_RS00925	COG4667	esterase of the alpha-beta hydrolase superfamily
BTR42_RS00935	COG2017	converts alpha-aldose to the beta-anomer
BTR42_RS00945	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTR42_RS00975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTR42_RS01000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTR42_RS01005	COG1609	Transcriptional regulator
BTR42_RS01010	COG1263	PTS System
BTR42_RS01010	COG2190	(PTS) system
BTR42_RS01010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS01025	COG1363	Peptidase, m42
BTR42_RS01035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTR42_RS01040	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTR42_RS01045	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS01050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTR42_RS01055	COG2188	Transcriptional regulator
BTR42_RS01060	COG1482	cell wall glycoprotein biosynthetic process
BTR42_RS01070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BTR42_RS01075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BTR42_RS01085	COG1653	transport
BTR42_RS01090	COG1175	transmembrane transport
BTR42_RS01095	COG0395	ABC-type sugar transport system, permease component
BTR42_RS01110	COG2188	Transcriptional regulator
BTR42_RS01115	COG1940	carbohydrate kinase activity
BTR42_RS01145	COG3842	ATPase activity
BTR42_RS01160	COG0698	ribose 5-phosphate isomerase
BTR42_RS01190	COG3775	system Galactitol-specific IIC component
BTR42_RS01200	COG3711	transcriptional antiterminator
BTR42_RS01205	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS01210	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTR42_RS01220	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BTR42_RS01225	COG2207	Transcriptional regulator
BTR42_RS01230	COG3345	alpha-galactosidase
BTR42_RS01235	COG1653	transport
BTR42_RS01240	COG1175	transmembrane transport
BTR42_RS01245	COG0395	ABC-type sugar transport system, permease component
BTR42_RS01250	COG0366	Alpha amylase catalytic
BTR42_RS01255	COG0366	Alpha amylase catalytic
BTR42_RS01260	COG1609	Transcriptional regulator
BTR42_RS01265	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BTR42_RS01270	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BTR42_RS01275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTR42_RS01285	COG1862	Preprotein translocase
BTR42_RS01290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BTR42_RS01295	COG4589	Belongs to the CDS family
BTR42_RS01330	COG0242	peptide deformylase activity
BTR42_RS01350	COG0346	lactoylglutathione lyase activity
BTR42_RS01355	COG0561	phosphatase activity
BTR42_RS01365	COG1454	alcohol dehydrogenase
BTR42_RS01365	COG1012	belongs to the aldehyde dehydrogenase family
BTR42_RS01380	COG1185	polyribonucleotide nucleotidyltransferase activity
BTR42_RS01390	COG1045	serine acetyltransferase
BTR42_RS01400	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BTR42_RS01430	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BTR42_RS01440	COG4974	Belongs to the 'phage' integrase family
BTR42_RS01470	COG3935	DnaD domain protein
BTR42_RS01500	COG4974	Belongs to the 'phage' integrase family
BTR42_RS01520	COG3942	CHAP domain
BTR42_RS01520	COG1705	Flagellar rod assembly protein muramidase FlgJ
BTR42_RS01535	COG0433	COG0433 Predicted ATPase
BTR42_RS01575	COG4115	mRNA cleavage
BTR42_RS01585	COG1674	ftsk spoiiie
BTR42_RS01620	COG1396	sequence-specific DNA binding
BTR42_RS01700	COG1216	Glycosyl transferase, family 2
BTR42_RS01700	COG1442	glycosyl transferase family 8
BTR42_RS01745	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BTR42_RS01760	COG0745	RESPONSE REGULATOR receiver
BTR42_RS01780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTR42_RS01785	COG2140	Oxalate decarboxylase
BTR42_RS01840	COG4716	Myosin-crossreactive antigen
BTR42_RS01845	COG1819	glycosyl
BTR42_RS01950	COG3830	Belongs to the UPF0237 family
BTR42_RS01955	COG2848	UPF0210 protein
BTR42_RS01965	COG0588	phosphoglycerate mutase activity
BTR42_RS01975	COG1705	Flagellar rod assembly protein muramidase FlgJ
BTR42_RS01990	COG0443	Heat shock 70 kDa protein
BTR42_RS02000	COG0596	Alpha beta hydrolase
BTR42_RS02010	COG0352	thiamine-phosphate diphosphorylase activity
BTR42_RS02010	COG0351	phosphomethylpyrimidine kinase
BTR42_RS02025	COG0668	transmembrane transport
BTR42_RS02040	COG0504	CTP synthase activity
BTR42_RS02055	COG0191	fructose-bisphosphate aldolase activity
BTR42_RS02080	COG1461	Dihydroxyacetone kinase
BTR42_RS02085	COG0129	dihydroxy-acid dehydratase activity
BTR42_RS02090	COG0028	Belongs to the TPP enzyme family
BTR42_RS02095	COG0440	acetolactate synthase activity
BTR42_RS02100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BTR42_RS02105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTR42_RS02120	COG1126	abc transporter atp-binding protein
BTR42_RS02125	COG0765	amino acid transport
BTR42_RS02145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTR42_RS02155	COG0719	Fe-S assembly protein
BTR42_RS02160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTR42_RS02170	COG0719	Fe-S assembly protein
BTR42_RS02175	COG1686	Belongs to the peptidase S11 family
BTR42_RS02180	COG4166	transmembrane transport
BTR42_RS02185	COG0601	transmembrane transport
BTR42_RS02190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTR42_RS02195	COG0444	Belongs to the ABC transporter superfamily
BTR42_RS02200	COG4608	Belongs to the ABC transporter superfamily
BTR42_RS02235	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BTR42_RS02235	COG2755	lipolytic protein G-D-S-L family
BTR42_RS02240	COG0527	aspartate kinase activity
BTR42_RS02245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTR42_RS02250	COG1024	Enoyl-CoA hydratase
BTR42_RS02260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTR42_RS02270	COG2070	2-Nitropropane dioxygenase
BTR42_RS02275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTR42_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
BTR42_RS02285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTR42_RS02300	COG0439	Biotin carboxylase
BTR42_RS02315	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BTR42_RS02325	COG3716	PTS system mannose fructose sorbose family IID component
BTR42_RS02330	COG3715	PTS system
BTR42_RS02340	COG0561	phosphatase activity
BTR42_RS02355	COG2252	PERMEase
BTR42_RS02360	COG0802	atpase or kinase
BTR42_RS02370	COG1316	TRANSCRIPTIONal
BTR42_RS02380	COG0537	adenosine 5'-monophosphoramidase activity
BTR42_RS02385	COG1131	(ABC) transporter
BTR42_RS02390	COG4473	ABC transporter
BTR42_RS02400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BTR42_RS02410	COG5001	Diguanylate cyclase
BTR42_RS02410	COG3300	MHYT domain
BTR42_RS02415	COG0463	Glycosyl transferase, family 2
BTR42_RS02440	COG0195	Participates in both transcription termination and antitermination
BTR42_RS02445	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BTR42_RS02455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BTR42_RS02460	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTR42_RS02480	COG2217	Heavy metal translocating P-type atpase
BTR42_RS02490	COG2860	membrane
BTR42_RS02495	COG0561	phosphatase activity
BTR42_RS02505	COG1309	transcriptional regulator
BTR42_RS02530	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTR42_RS02555	COG3711	transcriptional antiterminator
BTR42_RS02555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTR42_RS02595	COG1131	(ABC) transporter
BTR42_RS02605	COG1263	PTS System
BTR42_RS02605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS02605	COG2190	(PTS) system
BTR42_RS02610	COG1737	Transcriptional regulator
BTR42_RS02615	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS02620	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BTR42_RS02625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BTR42_RS02640	COG0768	penicillin binding
BTR42_RS02645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTR42_RS02650	COG0513	Belongs to the DEAD box helicase family
BTR42_RS02655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR42_RS02665	COG1126	abc transporter atp-binding protein
BTR42_RS02700	COG1476	TRANSCRIPTIONal
BTR42_RS02760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTR42_RS02915	COG3942	CHAP domain
BTR42_RS02915	COG1388	LysM domain
BTR42_RS02935	COG2095	MarC family integral membrane protein
BTR42_RS02940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTR42_RS02945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BTR42_RS02950	COG3579	cysteine-type endopeptidase activity
BTR42_RS02955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTR42_RS02960	COG3331	DNA recombination
BTR42_RS02970	COG3599	regulation of cell shape
BTR42_RS02980	COG0116	Belongs to the methyltransferase superfamily
BTR42_RS02995	COG1854	S-ribosylhomocysteine lyase activity
BTR42_RS03015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTR42_RS03020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTR42_RS03025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTR42_RS03025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTR42_RS03045	COG4585	Histidine kinase
BTR42_RS03050	COG2197	response regulator
BTR42_RS03060	COG1098	S1 RNA binding domain
BTR42_RS03070	COG1739	Uncharacterized protein family UPF0029
BTR42_RS03075	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BTR42_RS03080	COG1040	competence protein
BTR42_RS03155	COG3557	Belongs to the UPF0374 family
BTR42_RS03160	COG2137	regulation of response to DNA damage stimulus
BTR42_RS03170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTR42_RS03200	COG1428	Deoxynucleoside kinase
BTR42_RS03230	COG0519	Catalyzes the synthesis of GMP from XMP
BTR42_RS03240	COG0525	valine-tRNA ligase activity
BTR42_RS03275	COG0742	ribosomal rna small subunit methyltransferase
BTR42_RS03280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BTR42_RS03285	COG3480	Lon protease (S16) C-terminal proteolytic domain
BTR42_RS03295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BTR42_RS03305	COG0737	Belongs to the 5'-nucleotidase family
BTR42_RS03310	COG4470	Protein conserved in bacteria
BTR42_RS03325	COG1132	(ABC) transporter
BTR42_RS03330	COG1132	(ABC) transporter
BTR42_RS03345	COG4585	Histidine kinase
BTR42_RS03350	COG2197	response regulator
BTR42_RS03355	COG4842	Belongs to the WXG100 family
BTR42_RS03370	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTR42_RS03375	COG1674	ftsk spoiiie
BTR42_RS03500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTR42_RS03505	COG0512	Glutamine amidotransferase of anthranilate synthase
BTR42_RS03515	COG0134	indole-3-glycerol-phosphate synthase activity
BTR42_RS03520	COG0135	phosphoribosylanthranilate isomerase activity
BTR42_RS03525	COG0133	tryptophan synthase activity
BTR42_RS03530	COG0159	tryptophan synthase activity
BTR42_RS03535	COG1914	H( )-stimulated, divalent metal cation uptake system
BTR42_RS03545	COG0783	Belongs to the Dps family
BTR42_RS03555	COG1940	carbohydrate kinase activity
BTR42_RS03560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTR42_RS03580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTR42_RS03585	COG2207	Transcriptional regulator
BTR42_RS03590	COG1217	gtp-binding protein TYPA
BTR42_RS03625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTR42_RS03630	COG1799	cell septum assembly
BTR42_RS03645	COG3599	regulation of cell shape
BTR42_RS03665	COG0542	response to heat
BTR42_RS03680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BTR42_RS03685	COG4703	Protein of unknown function (DUF1797)
BTR42_RS03690	COG0765	amino acid transport
BTR42_RS03695	COG1126	abc transporter atp-binding protein
BTR42_RS03720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BTR42_RS03735	COG3942	CHAP domain
BTR42_RS03750	COG1376	ErfK ybiS ycfS ynhG family protein
BTR42_RS03770	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BTR42_RS03775	COG1438	arginine binding
BTR42_RS03780	COG0497	DNA recombination
BTR42_RS03785	COG1307	EDD domain protein, DegV family
BTR42_RS03790	COG2755	lipolytic protein G-D-S-L family
BTR42_RS03795	COG4698	Protein conserved in bacteria
BTR42_RS03810	COG3104	oligopeptide transport
BTR42_RS03815	COG0167	dihydroorotate dehydrogenase activity
BTR42_RS03820	COG0604	alcohol dehydrogenase
BTR42_RS03820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTR42_RS03820	COG3321	synthase
BTR42_RS03820	COG4221	oxidoreductase activity
BTR42_RS03825	COG0640	Transcriptional regulator
BTR42_RS03830	COG2217	Heavy metal translocating P-type atpase
BTR42_RS03835	COG2076	Multidrug Resistance protein
BTR42_RS03860	COG1827	regulation of RNA biosynthetic process
BTR42_RS03870	COG0768	penicillin binding
BTR42_RS03875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BTR42_RS03890	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTR42_RS03900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTR42_RS03920	COG0513	Belongs to the DEAD box helicase family
BTR42_RS03930	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BTR42_RS03935	COG0204	Acyl-transferase
BTR42_RS03940	COG1555	photosystem II stabilization
BTR42_RS03940	COG1596	polysaccharide export
BTR42_RS03945	COG2333	competence protein COMEC
BTR42_RS03945	COG0658	competence protein
BTR42_RS03950	COG1466	dna polymerase III delta subunit
BTR42_RS03955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTR42_RS03960	COG0217	transcriptional regulatory protein
BTR42_RS03975	COG1136	(ABC) transporter
BTR42_RS03980	COG0577	efflux transmembrane transporter activity
BTR42_RS03995	COG0363	glucosamine-6-phosphate deaminase activity
BTR42_RS04000	COG1187	pseudouridine synthase activity
BTR42_RS04020	COG0546	phosphoglycolate phosphatase activity
BTR42_RS04025	COG4122	O-methyltransferase activity
BTR42_RS04035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTR42_RS04045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTR42_RS04050	COG0436	Aminotransferase
BTR42_RS04070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BTR42_RS04075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BTR42_RS04080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTR42_RS04085	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTR42_RS04090	COG0583	DNA-binding transcription factor activity
BTR42_RS04095	COG0655	NAD(P)H dehydrogenase (quinone) activity
BTR42_RS04100	COG0656	L-ascorbic acid biosynthetic process
BTR42_RS04105	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTR42_RS04115	COG0656	L-ascorbic acid biosynthetic process
BTR42_RS04120	COG1902	pentaerythritol trinitrate reductase activity
BTR42_RS04130	COG0789	Transcriptional regulator
BTR42_RS04140	COG1476	TRANSCRIPTIONal
BTR42_RS04150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTR42_RS04150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTR42_RS04155	COG0307	riboflavin synthase, alpha
BTR42_RS04160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTR42_RS04160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTR42_RS04180	COG0656	L-ascorbic acid biosynthetic process
BTR42_RS04185	COG0656	L-ascorbic acid biosynthetic process
BTR42_RS04205	COG3859	Proton-coupled thiamine transporter YuaJ
BTR42_RS04210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTR42_RS04215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTR42_RS04220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTR42_RS04225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTR42_RS04230	COG0372	Belongs to the citrate synthase family
BTR42_RS04250	COG1609	Transcriptional regulator
BTR42_RS04255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTR42_RS04260	COG0251	oxidation-reduction process
BTR42_RS04270	COG1309	transcriptional regulator
BTR42_RS04325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTR42_RS04330	COG1660	Displays ATPase and GTPase activities
BTR42_RS04350	COG1396	sequence-specific DNA binding
BTR42_RS04375	COG1705	Flagellar rod assembly protein muramidase FlgJ
BTR42_RS04375	COG1388	LysM domain
BTR42_RS04385	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BTR42_RS04410	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BTR42_RS04420	COG0513	Belongs to the DEAD box helicase family
BTR42_RS04440	COG3326	Membrane
BTR42_RS04445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTR42_RS04450	COG0066	3-isopropylmalate dehydratase activity
BTR42_RS04455	COG1956	GAF domain-containing protein
BTR42_RS04460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTR42_RS04470	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BTR42_RS04470	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BTR42_RS04475	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BTR42_RS04490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTR42_RS04500	COG4109	DRTGG domain
BTR42_RS04505	COG0024	Methionine aminopeptidase
BTR42_RS04515	COG2246	polysaccharide biosynthetic process
BTR42_RS04520	COG4708	membrane
BTR42_RS04525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTR42_RS04530	COG1597	lipid kinase activity
BTR42_RS04535	COG1523	belongs to the glycosyl hydrolase 13 family
BTR42_RS04540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BTR42_RS04545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTR42_RS04550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTR42_RS04555	COG0297	glycogen (starch) synthase activity
BTR42_RS04560	COG0058	SHG alpha-glucan phosphorylase activity
BTR42_RS04570	COG0356	it plays a direct role in the translocation of protons across the membrane
BTR42_RS04575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BTR42_RS04610	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTR42_RS04630	COG4221	oxidoreductase activity
BTR42_RS04635	COG0789	Transcriptional regulator
BTR42_RS04640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BTR42_RS04645	COG0456	acetyltransferase
BTR42_RS04655	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BTR42_RS04660	COG1074	ATP-dependent DNA helicase activity
BTR42_RS04685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTR42_RS04700	COG0300	oxidoreductase activity
BTR42_RS04705	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BTR42_RS04705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTR42_RS04730	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BTR42_RS04770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTR42_RS04775	COG2384	SAM-dependent methyltransferase
BTR42_RS04785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BTR42_RS04795	COG1088	dTDP-glucose 4,6-dehydratase activity
BTR42_RS04805	COG1051	belongs to the nudix hydrolase family
BTR42_RS04810	COG0628	permease
BTR42_RS04815	COG0457	Tetratricopeptide repeat
BTR42_RS04825	COG0640	Transcriptional regulator
BTR42_RS04830	COG1902	pentaerythritol trinitrate reductase activity
BTR42_RS04835	COG0028	Belongs to the TPP enzyme family
BTR42_RS04840	COG3527	Alpha-acetolactate decarboxylase
BTR42_RS04845	COG0531	amino acid
BTR42_RS04850	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BTR42_RS04860	COG1126	abc transporter atp-binding protein
BTR42_RS04865	COG0765	amino acid transport
BTR42_RS04875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTR42_RS04890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTR42_RS04895	COG4187	Peptidase family M20/M25/M40
BTR42_RS04905	COG4120	Belongs to the binding-protein-dependent transport system permease family
BTR42_RS04910	COG3842	ATPase activity
BTR42_RS04955	COG0488	(ABC) transporter
BTR42_RS04965	COG1132	(ABC) transporter
BTR42_RS04970	COG1132	(ABC) transporter
BTR42_RS04980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTR42_RS04985	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTR42_RS04985	COG0022	dehydrogenase e1 component
BTR42_RS05000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTR42_RS05005	COG4605	iron ion homeostasis
BTR42_RS05010	COG4604	ABC transporter, ATP-binding protein
BTR42_RS05020	COG0697	spore germination
BTR42_RS05025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTR42_RS05030	COG0095	Lipoate-protein ligase
BTR42_RS05045	COG0583	DNA-binding transcription factor activity
BTR42_RS05055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BTR42_RS05095	COG0477	Major facilitator Superfamily
BTR42_RS05100	COG1053	succinate dehydrogenase
BTR42_RS05100	COG3976	FMN-binding domain protein
BTR42_RS05100	COG0431	NADPH-dependent FMN reductase
BTR42_RS05110	COG1053	succinate dehydrogenase
BTR42_RS05110	COG3976	FMN-binding domain protein
BTR42_RS05110	COG0431	NADPH-dependent FMN reductase
BTR42_RS05115	COG0431	NADPH-dependent FMN reductase
BTR42_RS05115	COG3976	FMN-binding domain protein
BTR42_RS05115	COG1053	succinate dehydrogenase
BTR42_RS05125	COG1937	Protein conserved in bacteria
BTR42_RS05135	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTR42_RS05165	COG0583	DNA-binding transcription factor activity
BTR42_RS05175	COG1028	Short-chain dehydrogenase reductase Sdr
BTR42_RS05180	COG1979	alcohol dehydrogenase
BTR42_RS05190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BTR42_RS05195	COG0789	Transcriptional regulator
BTR42_RS05200	COG0656	L-ascorbic acid biosynthetic process
BTR42_RS05225	COG1011	Hydrolase
BTR42_RS05235	COG0583	DNA-binding transcription factor activity
BTR42_RS05240	COG2855	membrane
BTR42_RS05245	COG1012	belongs to the aldehyde dehydrogenase family
BTR42_RS05255	COG0322	excinuclease ABC activity
BTR42_RS05280	COG1573	uracil-dna glycosylase
BTR42_RS05305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BTR42_RS05310	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BTR42_RS05340	COG1316	TRANSCRIPTIONal
BTR42_RS05360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTR42_RS05370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BTR42_RS05375	COG3475	LICD family
BTR42_RS05390	COG1442	glycosyl transferase family 8
BTR42_RS05390	COG1216	Glycosyl transferase, family 2
BTR42_RS05420	COG0167	dihydroorotate dehydrogenase activity
BTR42_RS05425	COG0284	orotidine-5'-phosphate decarboxylase activity
BTR42_RS05430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BTR42_RS05440	COG1881	PFAM PEBP family protein
BTR42_RS05460	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BTR42_RS05465	COG0187	DNA topoisomerase II activity
BTR42_RS05470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTR42_RS05475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTR42_RS05495	COG0539	negative regulation of cytoplasmic translation
BTR42_RS05505	COG1346	cytolysis
BTR42_RS05510	COG1380	Effector of murein hydrolase LrgA
BTR42_RS05530	COG1131	(ABC) transporter
BTR42_RS05535	COG1725	Transcriptional regulator
BTR42_RS05545	COG0205	6-phosphofructokinase activity
BTR42_RS05550	COG0469	pyruvate kinase activity
BTR42_RS05560	COG1132	(ABC) transporter
BTR42_RS05570	COG1132	(ABC) transporter
BTR42_RS05580	COG2213	PTS system mannitol-specific
BTR42_RS05585	COG3711	transcriptional antiterminator
BTR42_RS05590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTR42_RS05595	COG0246	Mannitol dehydrogenase
BTR42_RS05600	COG2824	Alkylphosphonate utilization operon protein PhnA
BTR42_RS05605	COG0765	amino acid transport
BTR42_RS05610	COG1126	abc transporter atp-binding protein
BTR42_RS05615	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BTR42_RS05620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTR42_RS05625	COG1115	amino acid carrier protein
BTR42_RS05630	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS05650	COG0628	permease
BTR42_RS05655	COG1442	glycosyl transferase family 8
BTR42_RS05665	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BTR42_RS05675	COG1104	cysteine desulfurase activity
BTR42_RS05690	COG2357	RelA SpoT domain protein
BTR42_RS05700	COG0564	pseudouridine synthase activity
BTR42_RS05705	COG0280	phosphate acetyltransferase
BTR42_RS05710	COG4221	oxidoreductase activity
BTR42_RS05720	COG0561	phosphatase activity
BTR42_RS05725	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS05735	COG1136	(ABC) transporter
BTR42_RS05740	COG0577	efflux transmembrane transporter activity
BTR42_RS05745	COG0516	GMP reductase activity
BTR42_RS05750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BTR42_RS05770	COG2233	PERMEase
BTR42_RS05800	COG2890	protein-(glutamine-N5) methyltransferase activity
BTR42_RS05805	COG0009	L-threonylcarbamoyladenylate synthase
BTR42_RS05830	COG1132	(ABC) transporter
BTR42_RS05850	COG3711	transcriptional antiterminator
BTR42_RS05865	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS05870	COG0519	Catalyzes the synthesis of GMP from XMP
BTR42_RS05870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTR42_RS05875	COG4106	trans-aconitate 2-methyltransferase activity
BTR42_RS05885	COG1819	glycosyl
BTR42_RS05890	COG1396	sequence-specific DNA binding
BTR42_RS05895	COG0366	Alpha amylase catalytic
BTR42_RS05895	COG5263	repeat protein
BTR42_RS05900	COG1396	sequence-specific DNA binding
BTR42_RS05905	COG0366	Alpha amylase catalytic
BTR42_RS05905	COG5263	repeat protein
BTR42_RS05915	COG0534	Mate efflux family protein
BTR42_RS05935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BTR42_RS05950	COG2188	Transcriptional regulator
BTR42_RS05980	COG1737	Transcriptional regulator
BTR42_RS05985	COG0673	inositol 2-dehydrogenase activity
BTR42_RS05995	COG0673	inositol 2-dehydrogenase activity
BTR42_RS06000	COG4115	mRNA cleavage
BTR42_RS06010	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BTR42_RS06015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTR42_RS06025	COG1132	(ABC) transporter
BTR42_RS06030	COG1132	(ABC) transporter
BTR42_RS06045	COG1129	ABC transporter
BTR42_RS06050	COG4974	Belongs to the 'phage' integrase family
BTR42_RS06060	COG5002	protein histidine kinase activity
BTR42_RS06065	COG0745	RESPONSE REGULATOR receiver
BTR42_RS06070	COG0577	efflux transmembrane transporter activity
BTR42_RS06075	COG1136	(ABC) transporter
BTR42_RS06085	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BTR42_RS06105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTR42_RS06110	COG0758	DNA mediated transformation
BTR42_RS06115	COG0110	maltose O-acetyltransferase activity
BTR42_RS06120	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BTR42_RS06125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BTR42_RS06145	COG0488	(ABC) transporter
BTR42_RS06160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTR42_RS06165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTR42_RS06170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTR42_RS06175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTR42_RS06210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTR42_RS06215	COG4684	Psort location CytoplasmicMembrane, score
BTR42_RS06220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTR42_RS06235	COG0346	lactoylglutathione lyase activity
BTR42_RS06240	COG3764	Sortase (surface protein transpeptidase)
BTR42_RS06260	COG1079	Belongs to the binding-protein-dependent transport system permease family
BTR42_RS06265	COG4603	Belongs to the binding-protein-dependent transport system permease family
BTR42_RS06270	COG3845	ABC transporter
BTR42_RS06275	COG1744	ABC transporter substrate-binding protein PnrA-like
BTR42_RS06280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BTR42_RS06285	COG2813	Specifically methylates the guanine in position
BTR42_RS06290	COG1072	(Pantothenic acid kinase))
BTR42_RS06300	COG5002	protein histidine kinase activity
BTR42_RS06305	COG0745	RESPONSE REGULATOR receiver
BTR42_RS06315	COG0704	Plays a role in the regulation of phosphate uptake
BTR42_RS06320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTR42_RS06325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTR42_RS06330	COG0581	inorganic phosphate transmembrane transporter activity
BTR42_RS06335	COG0573	inorganic phosphate transmembrane transporter activity
BTR42_RS06355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTR42_RS06375	COG0519	Catalyzes the synthesis of GMP from XMP
BTR42_RS06380	COG0483	inositol monophosphate 1-phosphatase activity
BTR42_RS06385	COG4476	Belongs to the UPF0223 family
BTR42_RS06390	COG1393	Belongs to the ArsC family
BTR42_RS06395	COG0196	riboflavin kinase activity
BTR42_RS06400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BTR42_RS06430	COG1129	ABC transporter
BTR42_RS06445	COG1132	(ABC) transporter
BTR42_RS06450	COG4988	ABC transporter
BTR42_RS06480	COG2873	o-acetylhomoserine
BTR42_RS06490	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BTR42_RS06535	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BTR42_RS06545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTR42_RS06550	COG1115	amino acid carrier protein
BTR42_RS06575	COG0561	phosphatase activity
BTR42_RS06595	COG2814	Major facilitator Superfamily
BTR42_RS06610	COG0561	phosphatase activity
BTR42_RS06615	COG0561	phosphatase activity
BTR42_RS06620	COG0110	maltose O-acetyltransferase activity
BTR42_RS06625	COG0300	oxidoreductase activity
BTR42_RS06630	COG1917	Cupin 2, conserved barrel domain protein
BTR42_RS06630	COG2207	Transcriptional regulator
BTR42_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
BTR42_RS06645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTR42_RS06655	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTR42_RS06660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTR42_RS06660	COG3711	transcriptional antiterminator
BTR42_RS06665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTR42_RS06685	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS06705	COG1263	PTS System
BTR42_RS06705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS06705	COG2190	(PTS) system
BTR42_RS06710	COG3711	transcriptional antiterminator
BTR42_RS06725	COG1177	transmembrane transport
BTR42_RS06730	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTR42_RS06740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BTR42_RS06765	COG0285	dihydrofolate synthase activity
BTR42_RS06770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR42_RS06775	COG1126	abc transporter atp-binding protein
BTR42_RS06780	COG4215	(ABC) transporter
BTR42_RS06790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTR42_RS06795	COG2962	Rard protein
BTR42_RS06810	COG0726	polysaccharide deacetylase
BTR42_RS06820	COG1309	transcriptional regulator
BTR42_RS06835	COG0222	ribosome binding
BTR42_RS06865	COG2040	homocysteine
BTR42_RS06870	COG0833	amino acid
BTR42_RS06885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTR42_RS06890	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BTR42_RS06895	COG3425	synthase
BTR42_RS06910	COG1272	protein, Hemolysin III
BTR42_RS06915	COG1304	FMN binding
BTR42_RS06930	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BTR42_RS06935	COG0435	Glutathione S-transferase
BTR42_RS06940	COG0435	Glutathione S-transferase
BTR42_RS06955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR42_RS06960	COG1126	abc transporter atp-binding protein
BTR42_RS06965	COG0765	amino acid transport
BTR42_RS06970	COG0765	amino acid transport
BTR42_RS06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR42_RS06990	COG0583	DNA-binding transcription factor activity
BTR42_RS06995	COG0656	L-ascorbic acid biosynthetic process
BTR42_RS07005	COG0745	RESPONSE REGULATOR receiver
BTR42_RS07010	COG2357	RelA SpoT domain protein
BTR42_RS07045	COG1132	(ABC) transporter
BTR42_RS07060	COG0242	peptide deformylase activity
BTR42_RS07065	COG0456	acetyltransferase
BTR42_RS07070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTR42_RS07085	COG0720	synthase
BTR42_RS07090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BTR42_RS07095	COG1132	(ABC) transporter
BTR42_RS07105	COG0488	(ABC) transporter
BTR42_RS07110	COG0617	tRNA 3'-terminal CCA addition
BTR42_RS07135	COG1388	LysM domain
BTR42_RS07135	COG1705	Flagellar rod assembly protein muramidase FlgJ
BTR42_RS07140	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BTR42_RS07160	COG0667	Aldo Keto reductase
BTR42_RS07170	COG0646	methionine synthase
BTR42_RS07170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTR42_RS07180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTR42_RS07180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTR42_RS07180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTR42_RS07185	COG1105	Belongs to the carbohydrate kinase PfkB family
BTR42_RS07190	COG1349	DNA-binding transcription factor activity
BTR42_RS07195	COG0492	ferredoxin-NADP+ reductase activity
BTR42_RS07200	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTR42_RS07205	COG0336	Belongs to the RNA methyltransferase TrmD family
BTR42_RS07210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BTR42_RS07230	COG1837	Belongs to the UPF0109 family
BTR42_RS07250	COG2521	methyltransferase
BTR42_RS07250	COG2136	Putative SAM-dependent methyltransferase
BTR42_RS07260	COG0577	efflux transmembrane transporter activity
BTR42_RS07265	COG1136	(ABC) transporter
BTR42_RS07280	COG0505	Belongs to the CarA family
BTR42_RS07285	COG0540	Belongs to the ATCase OTCase family
BTR42_RS07300	COG0564	pseudouridine synthase activity
BTR42_RS07310	COG0583	DNA-binding transcription factor activity
BTR42_RS07315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BTR42_RS07340	COG0301	tRNA thio-modification
BTR42_RS07345	COG1104	cysteine desulfurase activity
BTR42_RS07355	COG0285	dihydrofolate synthase activity
BTR42_RS07370	COG0287	Prephenate dehydrogenase
BTR42_RS07380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BTR42_RS07385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BTR42_RS07395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTR42_RS07400	COG1368	sulfuric ester hydrolase activity
BTR42_RS07405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BTR42_RS07410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BTR42_RS07415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BTR42_RS07440	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTR42_RS07455	COG3942	CHAP domain
BTR42_RS07465	COG0463	Glycosyl transferase, family 2
BTR42_RS07475	COG1368	sulfuric ester hydrolase activity
BTR42_RS07485	COG1442	glycosyl transferase family 8
BTR42_RS07485	COG1216	Glycosyl transferase, family 2
BTR42_RS07500	COG0463	Glycosyl transferase, family 2
BTR42_RS07510	COG1091	dTDP-4-dehydrorhamnose reductase activity
BTR42_RS07525	COG0444	Belongs to the ABC transporter superfamily
BTR42_RS07530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTR42_RS07535	COG0601	transmembrane transport
BTR42_RS07540	COG4166	transmembrane transport
BTR42_RS07545	COG2151	metal-sulfur cluster biosynthetic enzyme
BTR42_RS07550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTR42_RS07555	COG0358	DNA primase activity
BTR42_RS07560	COG1970	mechanosensitive ion channel activity
BTR42_RS07580	COG3764	Sortase (surface protein transpeptidase)
BTR42_RS07590	COG3843	relaxase mobilization nuclease domain protein
BTR42_RS07615	COG0551	DNA topoisomerase type I activity
BTR42_RS07615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTR42_RS07815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR42_RS07820	COG0436	Aminotransferase
BTR42_RS07825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR42_RS07835	COG0058	SHG alpha-glucan phosphorylase activity
BTR42_RS07840	COG1640	4-alpha-glucanotransferase
BTR42_RS07845	COG1609	Transcriptional regulator
BTR42_RS07855	COG1175	transmembrane transport
BTR42_RS07860	COG3833	ABC-type maltose transport systems, permease component
BTR42_RS07865	COG2816	NAD+ diphosphatase activity
BTR42_RS07870	COG0556	nucleotide-excision repair
BTR42_RS07875	COG0765	amino acid transport
BTR42_RS07880	COG1126	abc transporter atp-binding protein
BTR42_RS07885	COG0488	(ABC) transporter
BTR42_RS07905	COG1187	pseudouridine synthase activity
BTR42_RS07910	COG4166	transmembrane transport
BTR42_RS07915	COG4166	transmembrane transport
BTR42_RS07930	COG0659	secondary active sulfate transmembrane transporter activity
BTR42_RS07950	COG0590	tRNA wobble adenosine to inosine editing
BTR42_RS07955	COG0456	acetyltransferase
BTR42_RS08005	COG1396	sequence-specific DNA binding
BTR42_RS08015	COG1621	beta-fructofuranosidase activity
BTR42_RS08020	COG2207	Transcriptional regulator
BTR42_RS08030	COG1902	pentaerythritol trinitrate reductase activity
BTR42_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
BTR42_RS08045	COG3321	synthase
BTR42_RS08045	COG0604	alcohol dehydrogenase
BTR42_RS08080	COG3843	relaxase mobilization nuclease domain protein
BTR42_RS08110	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS08125	COG0395	ABC-type sugar transport system, permease component
BTR42_RS08130	COG1175	transmembrane transport
BTR42_RS08135	COG1653	transport
BTR42_RS08145	COG1917	Cupin 2, conserved barrel domain protein
BTR42_RS08145	COG2207	Transcriptional regulator
BTR42_RS08270	COG0270	DNA (cytosine-5-)-methyltransferase activity
BTR42_RS08295	COG1316	TRANSCRIPTIONal
BTR42_RS08300	COG0077	Prephenate dehydratase
BTR42_RS08305	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BTR42_RS08310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BTR42_RS08315	COG0481	GTPase activity
BTR42_RS08340	COG1518	maintenance of DNA repeat elements
BTR42_RS08345	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BTR42_RS08350	COG1501	Belongs to the glycosyl hydrolase 31 family
BTR42_RS08355	COG1940	carbohydrate kinase activity
BTR42_RS08365	COG4753	response regulator
BTR42_RS08365	COG2207	Transcriptional regulator
BTR42_RS08370	COG0657	acetylesterase activity
BTR42_RS08385	COG0395	ABC-type sugar transport system, permease component
BTR42_RS08390	COG1175	transmembrane transport
BTR42_RS08410	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS08425	COG0647	UMP catabolic process
BTR42_RS08430	COG1051	belongs to the nudix hydrolase family
BTR42_RS08440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTR42_RS08445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTR42_RS08455	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BTR42_RS08460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTR42_RS08465	COG3442	glutamine amidotransferase
BTR42_RS08470	COG0148	phosphopyruvate hydratase activity
BTR42_RS08490	COG1523	belongs to the glycosyl hydrolase 13 family
BTR42_RS08505	COG0107	imidazoleglycerol-phosphate synthase activity
BTR42_RS08515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BTR42_RS08525	COG0560	Phosphoserine phosphatase
BTR42_RS08530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BTR42_RS08540	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BTR42_RS08560	COG0187	DNA topoisomerase II activity
BTR42_RS08570	COG0772	Belongs to the SEDS family
BTR42_RS08585	COG0038	chloride channel
BTR42_RS08590	COG0287	Prephenate dehydrogenase
BTR42_RS08590	COG1605	Chorismate mutase
BTR42_RS08605	COG0716	FMN binding
BTR42_RS08615	COG1454	alcohol dehydrogenase
BTR42_RS08630	COG3250	beta-galactosidase activity
BTR42_RS08640	COG2207	Transcriptional regulator
BTR42_RS08660	COG3408	Glycogen debranching enzyme
BTR42_RS08665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTR42_RS08670	COG3507	Belongs to the glycosyl hydrolase 43 family
BTR42_RS08680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS08680	COG1263	PTS System
BTR42_RS08680	COG2190	(PTS) system
BTR42_RS08685	COG2207	Transcriptional regulator
BTR42_RS08685	COG1609	Transcriptional regulator
BTR42_RS08690	COG3250	beta-galactosidase activity
BTR42_RS08695	COG0235	Class ii aldolase
BTR42_RS08720	COG0017	Asparaginyl-tRNA synthetase
BTR42_RS08730	COG0436	Aminotransferase
BTR42_RS08740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTR42_RS08740	COG1199	ATP-dependent helicase activity
BTR42_RS08755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BTR42_RS08775	COG2177	Part of the ABC transporter FtsEX involved in
BTR42_RS08780	COG2884	Cell division ATP-binding protein ftsE
BTR42_RS08785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BTR42_RS08790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTR42_RS08815	COG1078	dGTPase activity
BTR42_RS08840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTR42_RS08855	COG0772	Belongs to the SEDS family
BTR42_RS08865	COG1164	Oligoendopeptidase f
BTR42_RS08870	COG0386	Belongs to the glutathione peroxidase family
BTR42_RS08890	COG0588	phosphoglycerate mutase activity
BTR42_RS08905	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BTR42_RS08925	COG1268	BioY protein
BTR42_RS08930	COG4443	Transcriptional Coactivator p15 (PC4)
BTR42_RS08940	COG0826	peptidase U32
BTR42_RS08990	COG2183	response to ionizing radiation
BTR42_RS09000	COG0701	Predicted permease
BTR42_RS09005	COG3689	TIGRFAM TIGR03943 family protein
BTR42_RS09015	COG0789	Transcriptional regulator
BTR42_RS09025	COG0552	protein localization to endoplasmic reticulum
BTR42_RS09030	COG0561	phosphatase activity
BTR42_RS09035	COG0561	phosphatase activity
BTR42_RS09045	COG1196	nuclear chromosome segregation
BTR42_RS09055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BTR42_RS09060	COG5002	protein histidine kinase activity
BTR42_RS09065	COG0745	RESPONSE REGULATOR receiver
BTR42_RS09070	COG1126	abc transporter atp-binding protein
BTR42_RS09075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR42_RS09080	COG0765	amino acid transport
BTR42_RS09085	COG0765	amino acid transport
BTR42_RS09105	COG0745	RESPONSE REGULATOR receiver
BTR42_RS09130	COG4716	Myosin-crossreactive antigen
BTR42_RS09195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTR42_RS09200	COG0438	transferase activity, transferring glycosyl groups
BTR42_RS09210	COG1609	Transcriptional regulator
BTR42_RS09215	COG0006	proline dipeptidase activity
BTR42_RS09225	COG2816	NAD+ diphosphatase activity
BTR42_RS09240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS09240	COG1263	PTS System
BTR42_RS09240	COG2190	(PTS) system
BTR42_RS09260	COG0583	DNA-binding transcription factor activity
BTR42_RS09265	COG0534	Mate efflux family protein
BTR42_RS09275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTR42_RS09300	COG0667	Aldo Keto reductase
BTR42_RS09310	COG2211	Major facilitator Superfamily
BTR42_RS09320	COG3394	polysaccharide catabolic process
BTR42_RS09325	COG1263	PTS System
BTR42_RS09325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS09325	COG2190	(PTS) system
BTR42_RS09340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS09340	COG2190	(PTS) system
BTR42_RS09340	COG1263	PTS System
BTR42_RS09360	COG0163	prenyltransferase activity
BTR42_RS09365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BTR42_RS09370	COG0583	DNA-binding transcription factor activity
BTR42_RS09375	COG1811	Na channel or pump
BTR42_RS09390	COG0778	Nitroreductase
BTR42_RS09395	COG2723	6-phospho-beta-galactosidase activity
BTR42_RS09400	COG2190	(PTS) system
BTR42_RS09400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS09400	COG1263	PTS System
BTR42_RS09415	COG0557	exoribonuclease II activity
BTR42_RS09430	COG2814	Major facilitator Superfamily
BTR42_RS09435	COG0237	dephospho-CoA kinase activity
BTR42_RS09450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTR42_RS09455	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BTR42_RS09460	COG0366	Alpha amylase catalytic
BTR42_RS09475	COG1702	phosphate starvation-inducible protein PhoH
BTR42_RS09485	COG4479	Belongs to the UPF0346 family
BTR42_RS09495	COG2996	Protein conserved in bacteria
BTR42_RS09530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTR42_RS09540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTR42_RS09555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BTR42_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
BTR42_RS09585	COG1695	Transcriptional regulator
BTR42_RS09605	COG0534	Mate efflux family protein
BTR42_RS09620	COG0640	Transcriptional regulator
BTR42_RS09625	COG0708	Exodeoxyribonuclease III
BTR42_RS09645	COG0656	L-ascorbic acid biosynthetic process
BTR42_RS09655	COG0583	DNA-binding transcription factor activity
BTR42_RS09660	COG1393	Belongs to the ArsC family
BTR42_RS09665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTR42_RS09675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTR42_RS09700	COG0004	ammonium transporteR
BTR42_RS09715	COG1774	PSP1 C-terminal conserved region
BTR42_RS09720	COG0470	DNA polymerase III
BTR42_RS09730	COG0517	IMP dehydrogenase activity
BTR42_RS09730	COG1227	inorganic diphosphatase activity
BTR42_RS09780	COG0583	DNA-binding transcription factor activity
BTR42_RS09785	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BTR42_RS09790	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BTR42_RS09795	COG0626	cystathionine gamma-synthase activity
BTR42_RS09800	COG2244	polysaccharide biosynthetic process
BTR42_RS09805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTR42_RS09810	COG1120	ATPase activity
BTR42_RS09815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTR42_RS09820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTR42_RS09825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTR42_RS09845	COG1227	inorganic diphosphatase activity
BTR42_RS09855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTR42_RS09860	COG1253	flavin adenine dinucleotide binding
BTR42_RS09865	COG1119	ATPase activity
BTR42_RS09870	COG0025	NhaP-type Na H and K H
BTR42_RS09880	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BTR42_RS09885	COG1242	4 iron, 4 sulfur cluster binding
BTR42_RS09890	COG0671	phosphoesterase, PA-phosphatase related
BTR42_RS09900	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BTR42_RS09910	COG0300	oxidoreductase activity
BTR42_RS09920	COG0531	amino acid
BTR42_RS09925	COG0569	domain protein
BTR42_RS09930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTR42_RS09935	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BTR42_RS09940	COG1187	pseudouridine synthase activity
BTR42_RS09955	COG0582	viral genome integration into host DNA
BTR42_RS09975	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BTR42_RS09980	COG3763	UPF0154 protein
BTR42_RS10000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTR42_RS10005	COG1254	Belongs to the acylphosphatase family
BTR42_RS10020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTR42_RS10030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTR42_RS10040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTR42_RS10050	COG1484	DNA-dependent DNA replication
BTR42_RS10065	COG5002	protein histidine kinase activity
BTR42_RS10070	COG0745	RESPONSE REGULATOR receiver
BTR42_RS10080	COG0501	Belongs to the peptidase M48B family
BTR42_RS10085	COG1704	LemA family
BTR42_RS10095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTR42_RS10100	COG0569	domain protein
BTR42_RS10110	COG1122	ATPase activity
BTR42_RS10130	COG1114	Component of the transport system for branched-chain amino acids
BTR42_RS10145	COG2910	NAD(P)H-binding
BTR42_RS10150	COG1959	2 iron, 2 sulfur cluster binding
BTR42_RS10175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR42_RS10180	COG1473	amidohydrolase
BTR42_RS10185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR42_RS10190	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BTR42_RS10195	COG0217	transcriptional regulatory protein
BTR42_RS10200	COG0702	epimerase
BTR42_RS10205	COG0789	Transcriptional regulator
BTR42_RS10210	COG1323	Belongs to the UPF0348 family
BTR42_RS10220	COG2226	methyltransferase
BTR42_RS10225	COG0799	negative regulation of ribosome biogenesis
BTR42_RS10230	COG1335	isochorismatase
BTR42_RS10235	COG1713	HD superfamily hydrolase involved in NAD metabolism
BTR42_RS10240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BTR42_RS10245	COG1534	Rna-binding protein
BTR42_RS10250	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BTR42_RS10255	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BTR42_RS10260	COG2814	Major facilitator Superfamily
BTR42_RS10265	COG1846	Transcriptional regulator
BTR42_RS10280	COG0154	amidase activity
BTR42_RS10285	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BTR42_RS10290	COG1335	isochorismatase
BTR42_RS10295	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BTR42_RS10300	COG0436	Aminotransferase
BTR42_RS10310	COG0589	response to stress
BTR42_RS10315	COG0561	phosphatase activity
BTR42_RS10320	COG0252	asparaginase activity
BTR42_RS10325	COG3655	Transcriptional regulator
BTR42_RS10345	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTR42_RS10360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTR42_RS10365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTR42_RS10375	COG1940	carbohydrate kinase activity
BTR42_RS10380	COG2190	(PTS) system
BTR42_RS10380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS10380	COG1263	PTS System
BTR42_RS10385	COG1621	beta-fructofuranosidase activity
BTR42_RS10390	COG1609	Transcriptional regulator
BTR42_RS10395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTR42_RS10405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTR42_RS10420	COG2131	deaminase
BTR42_RS10425	COG0006	proline dipeptidase activity
BTR42_RS10445	COG0598	Magnesium transport protein CorA
BTR42_RS10460	COG3655	Transcriptional regulator
BTR42_RS10470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BTR42_RS10475	COG0629	single-stranded DNA binding
BTR42_RS10495	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BTR42_RS10505	COG3634	alkyl hydroperoxide reductase activity
BTR42_RS10510	COG0450	alkyl hydroperoxide reductase
BTR42_RS10515	COG1116	anion transmembrane transporter activity
BTR42_RS10520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTR42_RS10530	COG0318	PFAM AMP-dependent synthetase and ligase
BTR42_RS10545	COG1194	a g-specific adenine glycosylase
BTR42_RS10555	COG2223	nitrite transmembrane transporter activity
BTR42_RS10580	COG1063	alcohol dehydrogenase
BTR42_RS10585	COG3118	belongs to the thioredoxin family
BTR42_RS10595	COG0157	Belongs to the NadC ModD family
BTR42_RS10605	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BTR42_RS10610	COG1396	sequence-specific DNA binding
BTR42_RS10620	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BTR42_RS10640	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BTR42_RS10645	COG0681	Belongs to the peptidase S26 family
BTR42_RS10705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTR42_RS10720	COG1882	Formate acetyltransferase
BTR42_RS10735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTR42_RS10755	COG5002	protein histidine kinase activity
BTR42_RS10770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTR42_RS10775	COG0581	inorganic phosphate transmembrane transporter activity
BTR42_RS10780	COG0573	inorganic phosphate transmembrane transporter activity
BTR42_RS10795	COG0789	Transcriptional regulator
BTR42_RS10810	COG2081	HI0933 family
BTR42_RS10830	COG1846	Transcriptional regulator
BTR42_RS10840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BTR42_RS10845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BTR42_RS10855	COG3414	Phosphotransferase system galactitol-specific IIB component
BTR42_RS10860	COG3775	system Galactitol-specific IIC component
BTR42_RS10870	COG1349	DNA-binding transcription factor activity
BTR42_RS10880	COG0456	acetyltransferase
BTR42_RS10885	COG1214	PFAM Peptidase M22, glycoprotease
BTR42_RS10890	COG5503	Protein of unknown function (DUF1447)
BTR42_RS10900	COG3942	CHAP domain
BTR42_RS10905	COG0493	'glutamate synthase
BTR42_RS10910	COG0069	glutamate synthase activity
BTR42_RS10910	COG0070	glutamate synthase
BTR42_RS10910	COG0067	glutamate synthase
BTR42_RS10915	COG0174	glutamine synthetase
BTR42_RS10920	COG0789	Transcriptional regulator
BTR42_RS10930	COG0126	phosphoglycerate kinase activity
BTR42_RS10940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTR42_RS10960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTR42_RS11005	COG3290	protein histidine kinase activity
BTR42_RS11055	COG0463	Glycosyl transferase, family 2
BTR42_RS11110	COG2274	protein secretion by the type I secretion system
BTR42_RS11115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTR42_RS11120	COG1266	CAAX protease self-immunity
BTR42_RS11145	COG0084	hydrolase, TatD family'
BTR42_RS11170	COG0681	Belongs to the peptidase S26 family
BTR42_RS11180	COG2226	methyltransferase
BTR42_RS11185	COG1132	(ABC) transporter
BTR42_RS11210	COG0281	malic enzyme
BTR42_RS11215	COG0583	DNA-binding transcription factor activity
BTR42_RS11230	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTR42_RS11235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTR42_RS11240	COG1696	Membrane protein involved in D-alanine export
BTR42_RS11295	COG1394	ATPase activity, coupled to movement of substances
BTR42_RS11300	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
BTR42_RS11310	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
BTR42_RS11315	COG1527	subunit (C
BTR42_RS11325	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BTR42_RS11330	COG1269	ATP hydrolysis coupled proton transport
BTR42_RS11365	COG1131	(ABC) transporter
BTR42_RS11380	COG0594	ribonuclease P activity
BTR42_RS11395	COG2211	Major facilitator Superfamily
BTR42_RS11405	COG2807	transmembrane transport
BTR42_RS11410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTR42_RS11435	COG0756	dUTP diphosphatase activity
BTR42_RS11460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTR42_RS11465	COG0705	Rhomboid family
BTR42_RS11465	COG0457	Tetratricopeptide repeat
BTR42_RS11470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTR42_RS11480	COG2171	N-acyltransferase activity
BTR42_RS11485	COG0166	Belongs to the GPI family
BTR42_RS11505	COG1234	tRNA 3'-trailer cleavage
BTR42_RS11510	COG1268	BioY protein
BTR42_RS11520	COG0343	queuine tRNA-ribosyltransferase activity
BTR42_RS11535	COG3479	Phenolic acid decarboxylase
BTR42_RS11540	COG1695	Transcriptional regulator
BTR42_RS11545	COG1832	CoA-binding protein
BTR42_RS11565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTR42_RS11565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTR42_RS11575	COG4978	Transcriptional regulator
BTR42_RS11575	COG0789	Transcriptional regulator
BTR42_RS11580	COG0534	Mate efflux family protein
BTR42_RS11585	COG0656	L-ascorbic acid biosynthetic process
BTR42_RS11595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTR42_RS11610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTR42_RS11610	COG3711	transcriptional antiterminator
BTR42_RS11615	COG0800	Aldolase
BTR42_RS11620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTR42_RS11655	COG3623	hexulose-6-phosphate isomerase
BTR42_RS11665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTR42_RS11675	COG3037	sugar-specific permease SgaT UlaA
BTR42_RS11685	COG1979	alcohol dehydrogenase
BTR42_RS11690	COG1464	Belongs to the NlpA lipoprotein family
BTR42_RS11695	COG2011	ABC-type metal ion transport system permease component
BTR42_RS11700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTR42_RS11710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BTR42_RS11715	COG2918	glutathione biosynthetic process
BTR42_RS11715	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTR42_RS11825	COG0582	viral genome integration into host DNA
BTR42_RS11855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTR42_RS11880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BTR42_RS11885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTR42_RS11890	COG0542	response to heat
BTR42_RS11895	COG4463	regulation of RNA biosynthetic process
BTR42_RS11915	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BTR42_RS11930	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTR42_RS11935	COG1396	sequence-specific DNA binding
BTR42_RS11940	COG3590	peptidase
BTR42_RS11950	COG0366	Alpha amylase catalytic
BTR42_RS11955	COG1263	PTS System
BTR42_RS11955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR42_RS11960	COG2188	Transcriptional regulator
BTR42_RS11985	COG0681	Belongs to the peptidase S26 family
BTR42_RS12000	COG2255	four-way junction helicase activity
BTR42_RS12005	COG0602	queuosine metabolic process
BTR42_RS12035	COG4472	Bacterial protein of unknown function (DUF965)
BTR42_RS12040	COG1393	Belongs to the ArsC family
BTR42_RS12115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTR42_RS12120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTR42_RS12140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTR42_RS12175	COG3759	membrane
BTR42_RS12180	COG1511	domain protein
BTR42_RS12185	COG1309	transcriptional regulator
BTR42_RS12195	COG4466	Protein conserved in bacteria
BTR42_RS12200	COG0305	Participates in initiation and elongation during chromosome replication
BTR42_RS12215	COG0445	tRNA wobble uridine modification
BTR42_RS12225	COG0482	sulfurtransferase activity
BTR42_RS12230	COG1760	l-serine dehydratase
BTR42_RS12235	COG1760	l-serine dehydratase
BTR42_RS12240	COG0546	phosphoglycolate phosphatase activity
BTR42_RS12245	COG0741	lytic transglycosylase activity
BTR42_RS12260	COG1122	ATPase activity
BTR42_RS12265	COG1122	ATPase activity
BTR42_RS12270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTR42_RS12280	COG0612	Peptidase, M16
BTR42_RS12285	COG0612	Peptidase, M16
BTR42_RS12360	COG1396	sequence-specific DNA binding
BTR42_RS12375	COG0582	viral genome integration into host DNA
BTR42_RS12385	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BTR42_RS12395	COG0517	IMP dehydrogenase activity
BTR42_RS12395	COG0516	GMP reductase activity
BTR42_RS12405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTR42_RS12410	COG0488	(ABC) transporter
BTR42_RS12440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTR42_RS12445	COG1475	DNA binding