locus-tag	class	description
CTW00_RS00010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CTW00_RS00015	COG1187	pseudouridine synthase activity
CTW00_RS00025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTW00_RS00050	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTW00_RS00055	COG3763	UPF0154 protein
CTW00_RS00075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTW00_RS00080	COG1254	Belongs to the acylphosphatase family
CTW00_RS00095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTW00_RS00140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CTW00_RS00150	COG1484	DNA-dependent DNA replication
CTW00_RS00160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CTW00_RS00170	COG0745	RESPONSE REGULATOR receiver
CTW00_RS00180	COG0501	Belongs to the peptidase M48B family
CTW00_RS00185	COG1704	LemA family
CTW00_RS00195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTW00_RS00200	COG0569	domain protein
CTW00_RS00210	COG3328	transposase activity
CTW00_RS00215	COG1114	Component of the transport system for branched-chain amino acids
CTW00_RS00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTW00_RS00235	COG1464	Belongs to the NlpA lipoprotein family
CTW00_RS00240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTW00_RS00255	COG0789	Transcriptional regulator
CTW00_RS00270	COG2226	methyltransferase
CTW00_RS00275	COG0799	negative regulation of ribosome biogenesis
CTW00_RS00280	COG1713	HD superfamily hydrolase involved in NAD metabolism
CTW00_RS00290	COG1534	Rna-binding protein
CTW00_RS00295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CTW00_RS00300	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CTW00_RS00350	COG1040	competence protein
CTW00_RS00355	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CTW00_RS00360	COG1739	Uncharacterized protein family UPF0029
CTW00_RS00375	COG1098	S1 RNA binding domain
CTW00_RS00385	COG2197	response regulator
CTW00_RS00390	COG4585	Histidine kinase
CTW00_RS00400	COG0515	serine threonine protein kinase
CTW00_RS00400	COG2815	serine threonine protein kinase
CTW00_RS00410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CTW00_RS00410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CTW00_RS00420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTW00_RS00425	COG1758	RNA polymerase activity
CTW00_RS00440	COG1854	S-ribosylhomocysteine lyase activity
CTW00_RS00450	COG0116	Belongs to the methyltransferase superfamily
CTW00_RS00465	COG4474	Belongs to the UPF0398 family
CTW00_RS00470	COG3331	DNA recombination
CTW00_RS00475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTW00_RS00480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTW00_RS00485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CTW00_RS00500	COG1113	amino acid transport
CTW00_RS00505	COG0492	ferredoxin-NADP+ reductase activity
CTW00_RS00515	COG1126	abc transporter atp-binding protein
CTW00_RS00520	COG0765	amino acid transport
CTW00_RS00525	COG0513	Belongs to the DEAD box helicase family
CTW00_RS00530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTW00_RS00535	COG0768	penicillin binding
CTW00_RS00545	COG0275	rRNA processing
CTW00_RS00555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CTW00_RS00565	COG1131	(ABC) transporter
CTW00_RS00585	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTW00_RS00590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CTW00_RS00615	COG0751	glycine-tRNA ligase activity
CTW00_RS00625	COG1755	Isoprenylcysteine carboxyl methyltransferase
CTW00_RS00630	COG0656	L-ascorbic acid biosynthetic process
CTW00_RS00645	COG0561	phosphatase activity
CTW00_RS00655	COG3250	beta-galactosidase activity
CTW00_RS00690	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CTW00_RS00695	COG0195	Participates in both transcription termination and antitermination
CTW00_RS00700	COG0779	Required for maturation of 30S ribosomal subunits
CTW00_RS00705	COG1368	sulfuric ester hydrolase activity
CTW00_RS00740	COG1131	(ABC) transporter
CTW00_RS00745	COG0537	adenosine 5'-monophosphoramidase activity
CTW00_RS00755	COG1316	TRANSCRIPTIONal
CTW00_RS00765	COG0802	atpase or kinase
CTW00_RS00770	COG2252	PERMEase
CTW00_RS00775	COG0561	phosphatase activity
CTW00_RS00790	COG3715	PTS system
CTW00_RS00795	COG3716	PTS system mannose fructose sorbose family IID component
CTW00_RS00810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CTW00_RS00830	COG0439	Biotin carboxylase
CTW00_RS00845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTW00_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
CTW00_RS00855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTW00_RS00870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CTW00_RS00880	COG1024	Enoyl-CoA hydratase
CTW00_RS00885	COG0484	heat shock protein binding
CTW00_RS00895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CTW00_RS00900	COG1420	regulation of RNA biosynthetic process
CTW00_RS00905	COG1705	Flagellar rod assembly protein muramidase FlgJ
CTW00_RS00905	COG1388	LysM domain
CTW00_RS00915	COG0588	phosphoglycerate mutase activity
CTW00_RS00920	COG2848	UPF0210 protein
CTW00_RS00925	COG3830	Belongs to the UPF0237 family
CTW00_RS00930	COG2261	transglycosylase associated protein
CTW00_RS00945	COG0154	amidase activity
CTW00_RS00950	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTW00_RS00955	COG0574	Belongs to the PEP-utilizing enzyme family
CTW00_RS00955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTW00_RS00960	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CTW00_RS00965	COG0517	IMP dehydrogenase activity
CTW00_RS00970	COG1054	Belongs to the UPF0176 family
CTW00_RS00985	COG1937	Protein conserved in bacteria
CTW00_RS00990	COG1335	isochorismatase
CTW00_RS00995	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CTW00_RS01000	COG0436	Aminotransferase
CTW00_RS01005	COG0589	response to stress
CTW00_RS01010	COG0561	phosphatase activity
CTW00_RS01020	COG0252	asparaginase activity
CTW00_RS01025	COG4989	oxidoreductase activity
CTW00_RS01030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTW00_RS01035	COG1129	ABC transporter
CTW00_RS01050	COG1132	(ABC) transporter
CTW00_RS01055	COG4988	ABC transporter
CTW00_RS01060	COG1120	ATPase activity
CTW00_RS01085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTW00_RS01090	COG0736	holo-[acyl-carrier-protein] synthase activity
CTW00_RS01095	COG0653	protein targeting
CTW00_RS01100	COG1482	cell wall glycoprotein biosynthetic process
CTW00_RS01105	COG1940	carbohydrate kinase activity
CTW00_RS01110	COG1263	PTS System
CTW00_RS01110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTW00_RS01110	COG2190	(PTS) system
CTW00_RS01115	COG1621	beta-fructofuranosidase activity
CTW00_RS01120	COG1609	Transcriptional regulator
CTW00_RS01125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CTW00_RS01145	COG2131	deaminase
CTW00_RS01150	COG0006	proline dipeptidase activity
CTW00_RS01180	COG1368	sulfuric ester hydrolase activity
CTW00_RS01205	COG1194	a g-specific adenine glycosylase
CTW00_RS01215	COG3118	belongs to the thioredoxin family
CTW00_RS01220	COG1193	negative regulation of DNA recombination
CTW00_RS01235	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTW00_RS01240	COG0681	Belongs to the peptidase S26 family
CTW00_RS01245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTW00_RS01260	COG1882	Formate acetyltransferase
CTW00_RS01275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTW00_RS01290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CTW00_RS01295	COG2936	dipeptidyl-peptidase activity
CTW00_RS01310	COG1705	Flagellar rod assembly protein muramidase FlgJ
CTW00_RS01310	COG3942	CHAP domain
CTW00_RS01375	COG1476	TRANSCRIPTIONal
CTW00_RS01410	COG0582	viral genome integration into host DNA
CTW00_RS01440	COG2081	HI0933 family
CTW00_RS01460	COG1214	PFAM Peptidase M22, glycoprotease
CTW00_RS01465	COG5503	Protein of unknown function (DUF1447)
CTW00_RS01475	COG4608	Belongs to the ABC transporter superfamily
CTW00_RS01480	COG0444	Belongs to the ABC transporter superfamily
CTW00_RS01485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTW00_RS01490	COG0601	transmembrane transport
CTW00_RS01495	COG4166	transmembrane transport
CTW00_RS01500	COG0174	glutamine synthetase
CTW00_RS01505	COG0789	Transcriptional regulator
CTW00_RS01520	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CTW00_RS01555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CTW00_RS01585	COG1288	antiporter activity
CTW00_RS01590	COG0549	Belongs to the carbamate kinase family
CTW00_RS01595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CTW00_RS01600	COG4191	Histidine kinase
CTW00_RS01605	COG0784	Response regulator, receiver
CTW00_RS01610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTW00_RS01615	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CTW00_RS01620	COG0084	hydrolase, TatD family'
CTW00_RS01645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTW00_RS01660	COG0395	ABC-type sugar transport system, permease component
CTW00_RS01685	COG0395	ABC-type sugar transport system, permease component
CTW00_RS01690	COG1175	transmembrane transport
CTW00_RS01725	COG3279	Response regulator of the LytR AlgR family
CTW00_RS01735	COG1131	(ABC) transporter
CTW00_RS01750	COG0594	ribonuclease P activity
CTW00_RS01755	COG0165	Argininosuccinate lyase
CTW00_RS01815	COG0756	dUTP diphosphatase activity
CTW00_RS01820	COG1263	PTS System
CTW00_RS01820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTW00_RS01825	COG0366	Alpha amylase catalytic
CTW00_RS01835	COG1737	Transcriptional regulator
CTW00_RS01840	COG2832	Protein of unknown function (DUF454)
CTW00_RS01870	COG1132	(ABC) transporter
CTW00_RS01875	COG1132	(ABC) transporter
CTW00_RS01885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CTW00_RS01890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTW00_RS01905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CTW00_RS01910	COG1215	transferase activity, transferring glycosyl groups
CTW00_RS01915	COG1473	amidohydrolase
CTW00_RS01925	COG0166	Belongs to the GPI family
CTW00_RS01970	COG1234	tRNA 3'-trailer cleavage
CTW00_RS01975	COG1268	BioY protein
CTW00_RS01990	COG0343	queuine tRNA-ribosyltransferase activity
CTW00_RS02000	COG0735	belongs to the Fur family
CTW00_RS02005	COG1832	CoA-binding protein
CTW00_RS02010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTW00_RS02010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CTW00_RS02020	COG4175	Glycine betaine
CTW00_RS02020	COG3448	diguanylate cyclase activity
CTW00_RS02025	COG1597	lipid kinase activity
CTW00_RS02035	COG0415	Belongs to the DNA photolyase family
CTW00_RS02060	COG3775	system Galactitol-specific IIC component
CTW00_RS02065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTW00_RS02075	COG1609	Transcriptional regulator
CTW00_RS02085	COG3623	hexulose-6-phosphate isomerase
CTW00_RS02095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTW00_RS02110	COG1929	Belongs to the glycerate kinase type-1 family
CTW00_RS02120	COG2964	Protein conserved in bacteria
CTW00_RS02125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTW00_RS02130	COG0626	cystathionine gamma-synthase activity
CTW00_RS02135	COG0251	oxidation-reduction process
CTW00_RS02145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CTW00_RS02170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTW00_RS02185	COG0564	pseudouridine synthase activity
CTW00_RS02205	COG0459	protein refolding
CTW00_RS02215	COG0542	response to heat
CTW00_RS02220	COG4463	regulation of RNA biosynthetic process
CTW00_RS02235	COG0025	NhaP-type Na H and K H
CTW00_RS02245	COG0450	alkyl hydroperoxide reductase
CTW00_RS02265	COG3590	peptidase
CTW00_RS02270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CTW00_RS02275	COG3959	Transketolase, thiamine diphosphate binding domain
CTW00_RS02290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTW00_RS02295	COG0366	Alpha amylase catalytic
CTW00_RS02300	COG1263	PTS System
CTW00_RS02300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTW00_RS02305	COG2188	Transcriptional regulator
CTW00_RS02315	COG0602	queuosine metabolic process
CTW00_RS02325	COG0673	inositol 2-dehydrogenase activity
CTW00_RS02335	COG1328	CTP reductase activity
CTW00_RS02365	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTW00_RS02370	COG4472	Bacterial protein of unknown function (DUF965)
CTW00_RS02375	COG1393	Belongs to the ArsC family
CTW00_RS02380	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CTW00_RS02390	COG0519	Catalyzes the synthesis of GMP from XMP
CTW00_RS02405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTW00_RS02425	COG0018	arginyl-trna synthetase
CTW00_RS02430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CTW00_RS02440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CTW00_RS02480	COG5002	protein histidine kinase activity
CTW00_RS02520	COG3759	membrane
CTW00_RS02530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CTW00_RS02540	COG0305	Participates in initiation and elongation during chromosome replication
CTW00_RS02545	COG0359	binds to the 23S rRNA
CTW00_RS02570	COG1760	l-serine dehydratase
CTW00_RS02575	COG1760	l-serine dehydratase
CTW00_RS02585	COG0741	lytic transglycosylase activity
CTW00_RS02605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTW00_RS02615	COG0612	Peptidase, M16
CTW00_RS02620	COG0612	Peptidase, M16
CTW00_RS02650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CTW00_RS02655	COG0488	(ABC) transporter
CTW00_RS02685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTW00_RS02690	COG1475	DNA binding
CTW00_RS02695	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CTW00_RS02700	COG0592	DNA-directed DNA polymerase activity
CTW00_RS02710	COG0012	GTP binding
CTW00_RS02715	COG0193	aminoacyl-tRNA hydrolase activity
CTW00_RS02720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTW00_RS02725	COG2244	polysaccharide biosynthetic process
CTW00_RS02730	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTW00_RS02760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTW00_RS02785	COG0531	amino acid
CTW00_RS02800	COG3328	transposase activity
CTW00_RS02930	COG3942	CHAP domain
CTW00_RS02940	COG0436	Aminotransferase
CTW00_RS02950	COG0416	fatty acid biosynthetic process
CTW00_RS02955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTW00_RS02960	COG2188	Transcriptional regulator
CTW00_RS02965	COG2222	sugar isomerase
CTW00_RS02985	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTW00_RS02990	COG3715	PTS system
CTW00_RS02995	COG3716	PTS system mannose fructose sorbose family IID component
CTW00_RS03000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTW00_RS03000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTW00_RS03020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTW00_RS03030	COG2255	four-way junction helicase activity
CTW00_RS03035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTW00_RS03045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CTW00_RS03045	COG2755	lipolytic protein G-D-S-L family
CTW00_RS03050	COG1454	alcohol dehydrogenase
CTW00_RS03050	COG1012	belongs to the aldehyde dehydrogenase family
CTW00_RS03075	COG0051	transcription antitermination factor activity, RNA binding
CTW00_RS03080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CTW00_RS03085	COG0088	Forms part of the polypeptide exit tunnel
CTW00_RS03090	COG0089	rRNA binding
CTW00_RS03110	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CTW00_RS03175	COG0200	Binds to the 23S rRNA
CTW00_RS03180	COG0201	protein transport
CTW00_RS03185	COG0563	adenylate kinase activity
CTW00_RS03200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CTW00_RS03365	COG1131	(ABC) transporter
CTW00_RS03405	COG1064	alcohol dehydrogenase
CTW00_RS03445	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CTW00_RS03460	COG1252	NADH dehydrogenase
CTW00_RS03465	COG1271	oxidase subunit
CTW00_RS03470	COG1294	oxidase, subunit
CTW00_RS03475	COG4988	ABC transporter
CTW00_RS03485	COG0142	geranyltranstransferase activity
CTW00_RS03490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CTW00_RS03500	COG1121	(ABC) transporter
CTW00_RS03505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTW00_RS03515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTW00_RS03515	COG4499	WXG100 protein secretion system (Wss), protein YukC
CTW00_RS03525	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CTW00_RS03535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTW00_RS03540	COG1459	type II secretion system
CTW00_RS03545	COG4537	Required for transformation and DNA binding
CTW00_RS03570	COG0827	DNA restriction-modification system
CTW00_RS03595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CTW00_RS03600	COG1363	Peptidase, m42
CTW00_RS03610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTW00_RS03615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTW00_RS03640	COG4120	Belongs to the binding-protein-dependent transport system permease family
CTW00_RS03645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTW00_RS03650	COG1428	Deoxynucleoside kinase
CTW00_RS03655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTW00_RS03660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTW00_RS03700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTW00_RS03715	COG1349	DNA-binding transcription factor activity
CTW00_RS03720	COG1882	Formate acetyltransferase
CTW00_RS03755	COG3328	transposase activity
CTW00_RS03785	COG2017	converts alpha-aldose to the beta-anomer
CTW00_RS03790	COG0745	RESPONSE REGULATOR receiver
CTW00_RS03795	COG5002	protein histidine kinase activity
CTW00_RS03805	COG4808	Protein conserved in bacteria
CTW00_RS03820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTW00_RS03840	COG1914	H( )-stimulated, divalent metal cation uptake system
CTW00_RS03845	COG1902	pentaerythritol trinitrate reductase activity
CTW00_RS03850	COG3711	transcriptional antiterminator
CTW00_RS03850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTW00_RS03855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTW00_RS03860	COG3775	system Galactitol-specific IIC component
CTW00_RS03865	COG3414	Phosphotransferase system galactitol-specific IIB component
CTW00_RS03915	COG0803	Belongs to the bacterial solute-binding protein 9 family
CTW00_RS03915	COG3443	Belongs to the bacterial solute-binding protein 9 family
CTW00_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
CTW00_RS03960	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CTW00_RS03965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTW00_RS03970	COG3715	PTS system
CTW00_RS03975	COG3716	PTS system mannose fructose sorbose family IID component
CTW00_RS03985	COG1609	Transcriptional regulator
CTW00_RS03990	COG5492	domain, Protein
CTW00_RS03995	COG1131	(ABC) transporter
CTW00_RS04005	COG4585	Histidine kinase
CTW00_RS04005	COG2203	Gaf domain
CTW00_RS04010	COG2197	response regulator
CTW00_RS04020	COG4978	Transcriptional regulator
CTW00_RS04020	COG0789	Transcriptional regulator
CTW00_RS04035	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CTW00_RS04040	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CTW00_RS04045	COG1012	belongs to the aldehyde dehydrogenase family
CTW00_RS04050	COG1882	Formate acetyltransferase
CTW00_RS04055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CTW00_RS04070	COG1012	belongs to the aldehyde dehydrogenase family
CTW00_RS04070	COG1454	alcohol dehydrogenase
CTW00_RS04085	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CTW00_RS04100	COG1012	belongs to the aldehyde dehydrogenase family
CTW00_RS04100	COG1454	alcohol dehydrogenase
CTW00_RS04105	COG4869	propanediol catabolic process
CTW00_RS04140	COG0577	efflux transmembrane transporter activity
CTW00_RS04145	COG1136	(ABC) transporter
CTW00_RS04150	COG0745	RESPONSE REGULATOR receiver
CTW00_RS04155	COG5002	protein histidine kinase activity
CTW00_RS04165	COG1396	sequence-specific DNA binding
CTW00_RS04205	COG3328	transposase activity
CTW00_RS04210	COG1131	(ABC) transporter
CTW00_RS04225	COG3328	transposase activity
CTW00_RS04280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTW00_RS04285	COG0512	Glutamine amidotransferase of anthranilate synthase
CTW00_RS04290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTW00_RS04295	COG0154	amidase activity
CTW00_RS04310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTW00_RS04325	COG2190	(PTS) system
CTW00_RS04325	COG1263	PTS System
CTW00_RS04325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTW00_RS04335	COG1363	Peptidase, m42
CTW00_RS04345	COG0737	Belongs to the 5'-nucleotidase family
CTW00_RS04375	COG3842	ATPase activity
CTW00_RS04390	COG1523	belongs to the glycosyl hydrolase 13 family
CTW00_RS04395	COG1609	Transcriptional regulator
CTW00_RS04400	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CTW00_RS04405	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CTW00_RS04410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTW00_RS04420	COG1862	Preprotein translocase
CTW00_RS04430	COG4589	Belongs to the CDS family
CTW00_RS04440	COG0442	prolyl-tRNA aminoacylation
CTW00_RS04480	COG0242	peptide deformylase activity
CTW00_RS04495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CTW00_RS04510	COG1045	serine acetyltransferase
CTW00_RS04520	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CTW00_RS04550	COG0383	alpha-mannosidase activity
CTW00_RS04565	COG4209	transmembrane transport
CTW00_RS04570	COG0395	ABC-type sugar transport system, permease component
CTW00_RS04575	COG1653	transport
CTW00_RS04585	COG2972	Histidine kinase
CTW00_RS04590	COG4753	response regulator
CTW00_RS04590	COG2207	Transcriptional regulator
CTW00_RS04595	COG2723	6-phospho-beta-galactosidase activity
CTW00_RS04615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTW00_RS04645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CTW00_RS04650	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTW00_RS04685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTW00_RS04730	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CTW00_RS04745	COG2851	Citrate transporter
CTW00_RS04755	COG0511	ligase activity, forming carbon-carbon bonds
CTW00_RS04760	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CTW00_RS04765	COG3052	prosthetic group binding
CTW00_RS04790	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CTW00_RS04800	COG0392	lysyltransferase activity
CTW00_RS04800	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CTW00_RS04815	COG1122	ATPase activity
CTW00_RS04820	COG4720	Psort location CytoplasmicMembrane, score
CTW00_RS04865	COG0527	aspartate kinase activity
CTW00_RS04870	COG0101	tRNA pseudouridine synthase activity
CTW00_RS04875	COG0352	thiamine-phosphate diphosphorylase activity
CTW00_RS04875	COG0351	phosphomethylpyrimidine kinase
CTW00_RS04880	COG4720	Psort location CytoplasmicMembrane, score
CTW00_RS04890	COG0668	transmembrane transport
CTW00_RS04895	COG0544	peptidyl-prolyl cis-trans isomerase activity
CTW00_RS04900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTW00_RS04905	COG3343	RNA polymerase activity
CTW00_RS04915	COG3275	phosphorelay sensor kinase activity
CTW00_RS04920	COG3279	Response regulator of the LytR AlgR family
CTW00_RS04930	COG1346	cytolysis
CTW00_RS04980	COG1126	abc transporter atp-binding protein
CTW00_RS04985	COG0765	amino acid transport
CTW00_RS05000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTW00_RS05010	COG0719	Fe-S assembly protein
CTW00_RS05015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTW00_RS05025	COG0719	Fe-S assembly protein
CTW00_RS05040	COG1686	Belongs to the peptidase S11 family
CTW00_RS05045	COG1686	Belongs to the peptidase S11 family
CTW00_RS05050	COG4166	transmembrane transport
CTW00_RS05055	COG0601	transmembrane transport
CTW00_RS05060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTW00_RS05065	COG0444	Belongs to the ABC transporter superfamily
CTW00_RS05145	COG2137	regulation of response to DNA damage stimulus
CTW00_RS05155	COG1442	glycosyl transferase family 8
CTW00_RS05155	COG1216	Glycosyl transferase, family 2
CTW00_RS05170	COG1216	Glycosyl transferase, family 2
CTW00_RS05170	COG1442	glycosyl transferase family 8
CTW00_RS05175	COG1442	glycosyl transferase family 8
CTW00_RS05200	COG1073	alpha beta
CTW00_RS05235	COG3328	transposase activity
CTW00_RS05260	COG1131	(ABC) transporter
CTW00_RS05265	COG2207	Transcriptional regulator
CTW00_RS05275	COG1175	transmembrane transport
CTW00_RS05280	COG0395	ABC-type sugar transport system, permease component
CTW00_RS05295	COG1247	-acetyltransferase
CTW00_RS05315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CTW00_RS05320	COG0586	Pfam SNARE associated Golgi protein
CTW00_RS05325	COG1668	transmembrane transport
CTW00_RS05330	COG4152	abc transporter atp-binding protein
CTW00_RS05365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTW00_RS05410	COG3591	Belongs to the peptidase S1B family
CTW00_RS05445	COG2972	Histidine kinase
CTW00_RS05450	COG4753	response regulator
CTW00_RS05450	COG2207	Transcriptional regulator
CTW00_RS05455	COG1840	ABC-type Fe3 transport system, periplasmic component
CTW00_RS05460	COG3842	ATPase activity
CTW00_RS05465	COG1178	ABC-type Fe3 transport system permease component
CTW00_RS05470	COG0673	inositol 2-dehydrogenase activity
CTW00_RS05500	COG0454	-acetyltransferase
CTW00_RS05510	COG1288	antiporter activity
CTW00_RS05515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CTW00_RS05520	COG0549	Belongs to the carbamate kinase family
CTW00_RS05530	COG0742	ribosomal rna small subunit methyltransferase
CTW00_RS05535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CTW00_RS05545	COG1609	Transcriptional regulator
CTW00_RS05550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTW00_RS05555	COG1869	D-ribose catabolic process
CTW00_RS05565	COG1172	Belongs to the binding-protein-dependent transport system permease family
CTW00_RS05570	COG1879	ABC-type sugar transport system periplasmic component
CTW00_RS05575	COG0737	Belongs to the 5'-nucleotidase family
CTW00_RS05580	COG4470	Protein conserved in bacteria
CTW00_RS05585	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CTW00_RS05595	COG1132	(ABC) transporter
CTW00_RS05600	COG1132	(ABC) transporter
CTW00_RS05615	COG1940	carbohydrate kinase activity
CTW00_RS05620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTW00_RS05625	COG1217	gtp-binding protein TYPA
CTW00_RS05635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CTW00_RS05640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CTW00_RS05660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CTW00_RS05665	COG1799	cell septum assembly
CTW00_RS05680	COG3599	regulation of cell shape
CTW00_RS05700	COG0542	response to heat
CTW00_RS05705	COG4703	Protein of unknown function (DUF1797)
CTW00_RS05710	COG0765	amino acid transport
CTW00_RS05715	COG1126	abc transporter atp-binding protein
CTW00_RS05720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CTW00_RS05740	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CTW00_RS05745	COG1438	arginine binding
CTW00_RS05750	COG0497	DNA recombination
CTW00_RS05765	COG2755	lipolytic protein G-D-S-L family
CTW00_RS05780	COG2217	Heavy metal translocating P-type atpase
CTW00_RS05790	COG0167	dihydroorotate dehydrogenase activity
CTW00_RS05800	COG1827	regulation of RNA biosynthetic process
CTW00_RS05810	COG2116	formate transmembrane transporter activity
CTW00_RS05815	COG0768	penicillin binding
CTW00_RS05820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTW00_RS05825	COG1181	Belongs to the D-alanine--D-alanine ligase family
CTW00_RS05830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTW00_RS05860	COG0561	phosphatase activity
CTW00_RS05865	COG0513	Belongs to the DEAD box helicase family
CTW00_RS05880	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CTW00_RS05885	COG0204	Acyl-transferase
CTW00_RS05890	COG1596	polysaccharide export
CTW00_RS05890	COG1555	photosystem II stabilization
CTW00_RS05895	COG2333	competence protein COMEC
CTW00_RS05895	COG0658	competence protein
CTW00_RS05930	COG1187	pseudouridine synthase activity
CTW00_RS05940	COG3328	transposase activity
CTW00_RS05970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTW00_RS05975	COG4122	O-methyltransferase activity
CTW00_RS05980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTW00_RS06000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTW00_RS06005	COG0436	Aminotransferase
CTW00_RS06010	COG2801	Transposase and inactivated derivatives
CTW00_RS06015	COG2801	Transposase and inactivated derivatives
CTW00_RS06030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTW00_RS06035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTW00_RS06040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTW00_RS06060	COG0726	polysaccharide deacetylase
CTW00_RS06065	COG0513	Belongs to the DEAD box helicase family
CTW00_RS06070	COG0572	uridine kinase
CTW00_RS06085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTW00_RS06105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CTW00_RS06115	COG2211	Major facilitator Superfamily
CTW00_RS06120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTW00_RS06125	COG2186	Transcriptional regulator
CTW00_RS06130	COG0800	Aldolase
CTW00_RS06140	COG1312	Catalyzes the dehydration of D-mannonate
CTW00_RS06145	COG1028	Short-chain dehydrogenase reductase Sdr
CTW00_RS06170	COG4109	DRTGG domain
CTW00_RS06175	COG0024	Methionine aminopeptidase
CTW00_RS06260	COG0577	efflux transmembrane transporter activity
CTW00_RS06260	COG1136	(ABC) transporter
CTW00_RS06270	COG0584	glycerophosphoryl diester phosphodiesterase
CTW00_RS06285	COG3328	transposase activity
CTW00_RS06300	COG0318	PFAM AMP-dependent synthetase and ligase
CTW00_RS06305	COG1960	acyl-CoA dehydrogenase activity
CTW00_RS06310	COG0427	acetyl-CoA hydrolase
CTW00_RS06315	COG1024	Enoyl-CoA hydratase
CTW00_RS06315	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTW00_RS06320	COG0183	Belongs to the thiolase family
CTW00_RS06325	COG0583	DNA-binding transcription factor activity
CTW00_RS06330	COG2050	protein possibly involved in aromatic compounds catabolism
CTW00_RS06335	COG4619	ABC transporter
CTW00_RS06340	COG0390	transport system, permease component
CTW00_RS06345	COG4868	Belongs to the UPF0371 family
CTW00_RS06350	COG2814	Major facilitator Superfamily
CTW00_RS06365	COG1187	pseudouridine synthase activity
CTW00_RS06370	COG0598	Magnesium transport protein CorA
CTW00_RS06375	COG1132	(ABC) transporter
CTW00_RS06385	COG2309	aminopeptidase activity
CTW00_RS06395	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CTW00_RS06410	COG0488	(ABC) transporter
CTW00_RS06415	COG1126	abc transporter atp-binding protein
CTW00_RS06425	COG0556	nucleotide-excision repair
CTW00_RS06440	COG1696	Membrane protein involved in D-alanine export
CTW00_RS06445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTW00_RS06450	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CTW00_RS06455	COG2182	Extracellular solute-binding protein
CTW00_RS06460	COG0366	Alpha amylase catalytic
CTW00_RS06470	COG1175	transmembrane transport
CTW00_RS06475	COG3833	ABC-type maltose transport systems, permease component
CTW00_RS06495	COG3833	ABC-type maltose transport systems, permease component
CTW00_RS06500	COG1175	transmembrane transport
CTW00_RS06510	COG1609	Transcriptional regulator
CTW00_RS06515	COG1640	4-alpha-glucanotransferase
CTW00_RS06520	COG0058	SHG alpha-glucan phosphorylase activity
CTW00_RS06530	COG1054	Belongs to the UPF0176 family
CTW00_RS06555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTW00_RS06570	COG0300	oxidoreductase activity
CTW00_RS06575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTW00_RS06575	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CTW00_RS06580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CTW00_RS06590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTW00_RS06595	COG2384	SAM-dependent methyltransferase
CTW00_RS06610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTW00_RS06615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CTW00_RS06625	COG1088	dTDP-glucose 4,6-dehydratase activity
CTW00_RS06635	COG2706	6-phosphogluconolactonase activity
CTW00_RS06655	COG0628	permease
CTW00_RS06660	COG0457	Tetratricopeptide repeat
CTW00_RS06665	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CTW00_RS06680	COG3842	ATPase activity
CTW00_RS06700	COG0488	(ABC) transporter
CTW00_RS06710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CTW00_RS06715	COG0022	dehydrogenase e1 component
CTW00_RS06715	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTW00_RS06720	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTW00_RS06730	COG0095	Lipoate-protein ligase
CTW00_RS06735	COG3442	glutamine amidotransferase
CTW00_RS06740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTW00_RS06745	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CTW00_RS06755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTW00_RS06765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTW00_RS06795	COG1518	maintenance of DNA repeat elements
CTW00_RS06800	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CTW00_RS06820	COG0481	GTPase activity
CTW00_RS06830	COG1418	mRNA catabolic process
CTW00_RS06845	COG0656	L-ascorbic acid biosynthetic process
CTW00_RS06860	COG2259	Doxx family
CTW00_RS06865	COG1011	Hydrolase
CTW00_RS06870	COG1012	belongs to the aldehyde dehydrogenase family
CTW00_RS06875	COG0322	excinuclease ABC activity
CTW00_RS06895	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CTW00_RS06905	COG1393	Belongs to the ArsC family
CTW00_RS06915	COG0813	purine-nucleoside phosphorylase activity
CTW00_RS06925	COG0583	DNA-binding transcription factor activity
CTW00_RS06930	COG1316	TRANSCRIPTIONal
CTW00_RS06955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTW00_RS06965	COG4641	Protein conserved in bacteria
CTW00_RS06965	COG0438	transferase activity, transferring glycosyl groups
CTW00_RS06970	COG0110	maltose O-acetyltransferase activity
CTW00_RS07035	COG1881	PFAM PEBP family protein
CTW00_RS07045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTW00_RS07050	COG0765	amino acid transport
CTW00_RS07055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CTW00_RS07060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CTW00_RS07070	COG0187	DNA topoisomerase II activity
CTW00_RS07085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTW00_RS07105	COG0539	negative regulation of cytoplasmic translation
CTW00_RS07135	COG1131	(ABC) transporter
CTW00_RS07140	COG1725	Transcriptional regulator
CTW00_RS07150	COG0205	6-phosphofructokinase activity
CTW00_RS07155	COG0469	pyruvate kinase activity
CTW00_RS07170	COG2213	PTS system mannitol-specific
CTW00_RS07175	COG3711	transcriptional antiterminator
CTW00_RS07180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTW00_RS07185	COG0246	Mannitol dehydrogenase
CTW00_RS07190	COG2824	Alkylphosphonate utilization operon protein PhnA
CTW00_RS07195	COG0765	amino acid transport
CTW00_RS07200	COG1126	abc transporter atp-binding protein
CTW00_RS07205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTW00_RS07215	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CTW00_RS07220	COG1115	amino acid carrier protein
CTW00_RS07230	COG2261	transglycosylase associated protein
CTW00_RS07275	COG1136	(ABC) transporter
CTW00_RS07305	COG0196	riboflavin kinase activity
CTW00_RS07315	COG4476	Belongs to the UPF0223 family
CTW00_RS07320	COG0483	inositol monophosphate 1-phosphatase activity
CTW00_RS07330	COG0573	inorganic phosphate transmembrane transporter activity
CTW00_RS07335	COG0581	inorganic phosphate transmembrane transporter activity
CTW00_RS07350	COG0704	Plays a role in the regulation of phosphate uptake
CTW00_RS07360	COG0745	RESPONSE REGULATOR receiver
CTW00_RS07365	COG5002	protein histidine kinase activity
CTW00_RS07380	COG2813	Specifically methylates the guanine in position
CTW00_RS07385	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CTW00_RS07390	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CTW00_RS07395	COG0295	cytidine deaminase activity
CTW00_RS07400	COG1744	ABC transporter substrate-binding protein PnrA-like
CTW00_RS07405	COG3845	ABC transporter
CTW00_RS07410	COG4603	Belongs to the binding-protein-dependent transport system permease family
CTW00_RS07415	COG1079	Belongs to the binding-protein-dependent transport system permease family
CTW00_RS07430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTW00_RS07435	COG4684	Psort location CytoplasmicMembrane, score
CTW00_RS07440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTW00_RS07445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTW00_RS07455	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CTW00_RS07460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTW00_RS07465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CTW00_RS07470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTW00_RS07475	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CTW00_RS07475	COG1328	CTP reductase activity
CTW00_RS07480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTW00_RS07485	COG0488	(ABC) transporter
CTW00_RS07510	COG1272	protein, Hemolysin III
CTW00_RS07530	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CTW00_RS07540	COG0110	maltose O-acetyltransferase activity
CTW00_RS07545	COG0758	DNA mediated transformation
CTW00_RS07550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CTW00_RS07555	COG0583	DNA-binding transcription factor activity
CTW00_RS07580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CTW00_RS07590	COG1136	(ABC) transporter
CTW00_RS07595	COG0577	efflux transmembrane transporter activity
CTW00_RS07600	COG0745	RESPONSE REGULATOR receiver
CTW00_RS07605	COG2205	protein histidine kinase activity
CTW00_RS07615	COG4974	Belongs to the 'phage' integrase family
CTW00_RS07625	COG0515	serine threonine protein kinase
CTW00_RS07625	COG2815	serine threonine protein kinase
CTW00_RS07665	COG0662	Cupin 2, conserved barrel domain protein
CTW00_RS07670	COG0673	inositol 2-dehydrogenase activity
CTW00_RS07685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTW00_RS07690	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CTW00_RS07695	COG2188	Transcriptional regulator
CTW00_RS07725	COG3104	oligopeptide transport
CTW00_RS07730	COG0386	Belongs to the glutathione peroxidase family
CTW00_RS07750	COG3328	transposase activity
CTW00_RS07760	COG0346	lactoylglutathione lyase activity
CTW00_RS07765	COG3764	Sortase (surface protein transpeptidase)
CTW00_RS07775	COG0039	L-malate dehydrogenase activity
CTW00_RS07795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CTW00_RS07800	COG3153	acetyltransferase
CTW00_RS07805	COG0009	L-threonylcarbamoyladenylate synthase
CTW00_RS07810	COG2890	protein-(glutamine-N5) methyltransferase activity
CTW00_RS07815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CTW00_RS07850	COG2801	Transposase and inactivated derivatives
CTW00_RS07855	COG2233	PERMEase
CTW00_RS07865	COG0516	GMP reductase activity
CTW00_RS07870	COG1174	glycine betaine transport
CTW00_RS07875	COG0517	IMP dehydrogenase activity
CTW00_RS07875	COG1125	glycine betaine transport
CTW00_RS07890	COG4221	oxidoreductase activity
CTW00_RS07895	COG0280	phosphate acetyltransferase
CTW00_RS07900	COG0564	pseudouridine synthase activity
CTW00_RS07910	COG2357	RelA SpoT domain protein
CTW00_RS07925	COG1104	cysteine desulfurase activity
CTW00_RS07945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CTW00_RS07955	COG0628	permease
CTW00_RS07960	COG2723	6-phospho-beta-galactosidase activity
CTW00_RS07975	COG2723	6-phospho-beta-galactosidase activity
CTW00_RS07980	COG2207	Transcriptional regulator
CTW00_RS07985	COG2190	(PTS) system
CTW00_RS07985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CTW00_RS07985	COG1263	PTS System
CTW00_RS08010	COG3493	citrate carrier protein
CTW00_RS08015	COG3290	protein histidine kinase activity
CTW00_RS08020	COG4565	transcriptional regulatory protein
CTW00_RS08030	COG1177	transmembrane transport
CTW00_RS08035	COG1176	ABC-type spermidine putrescine transport system, permease component I
CTW00_RS08045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CTW00_RS08050	COG2826	transposase and inactivated derivatives, IS30 family
CTW00_RS08055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTW00_RS08070	COG0302	gtp cyclohydrolase
CTW00_RS08075	COG0285	dihydrofolate synthase activity
CTW00_RS08080	COG0083	homoserine kinase activity
CTW00_RS08095	COG3328	transposase activity
CTW00_RS08155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CTW00_RS08165	COG3425	synthase
CTW00_RS08175	COG1304	FMN binding
CTW00_RS08190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CTW00_RS08195	COG1132	(ABC) transporter
CTW00_RS08200	COG1132	(ABC) transporter
CTW00_RS08205	COG0737	Belongs to the 5'-nucleotidase family
CTW00_RS08210	COG0242	peptide deformylase activity
CTW00_RS08215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTW00_RS08220	COG1132	(ABC) transporter
CTW00_RS08235	COG0488	(ABC) transporter
CTW00_RS08240	COG0617	tRNA 3'-terminal CCA addition
CTW00_RS08245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CTW00_RS08270	COG1388	LysM domain
CTW00_RS08270	COG1705	Flagellar rod assembly protein muramidase FlgJ
CTW00_RS08275	COG1705	Flagellar rod assembly protein muramidase FlgJ
CTW00_RS08275	COG1388	LysM domain
CTW00_RS08280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTW00_RS08280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTW00_RS08280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTW00_RS08285	COG1105	Belongs to the carbohydrate kinase PfkB family
CTW00_RS08290	COG1349	DNA-binding transcription factor activity
CTW00_RS08310	COG0336	Belongs to the RNA methyltransferase TrmD family
CTW00_RS08315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTW00_RS08325	COG1837	Belongs to the UPF0109 family
CTW00_RS08330	COG0228	four-way junction DNA binding
CTW00_RS08340	COG0577	efflux transmembrane transporter activity
CTW00_RS08345	COG1136	(ABC) transporter
CTW00_RS08360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CTW00_RS08365	COG0564	pseudouridine synthase activity
CTW00_RS08375	COG0583	DNA-binding transcription factor activity
CTW00_RS08380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CTW00_RS08420	COG1104	cysteine desulfurase activity
CTW00_RS08430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTW00_RS08455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CTW00_RS08460	COG1368	sulfuric ester hydrolase activity
CTW00_RS08470	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CTW00_RS08480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CTW00_RS08520	COG1216	Glycosyl transferase, family 2
CTW00_RS08520	COG1442	glycosyl transferase family 8
CTW00_RS08535	COG0463	Glycosyl transferase, family 2
CTW00_RS08570	COG0463	Glycosyl transferase, family 2
CTW00_RS08585	COG2151	metal-sulfur cluster biosynthetic enzyme
CTW00_RS08590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CTW00_RS08595	COG0358	DNA primase activity
CTW00_RS08600	COG1970	mechanosensitive ion channel activity
CTW00_RS08610	COG1074	ATP-dependent DNA helicase activity
CTW00_RS08620	COG2321	neutral zinc metallopeptidase
CTW00_RS08625	COG1136	(ABC) transporter
CTW00_RS08630	COG0577	efflux transmembrane transporter activity
CTW00_RS08675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CTW00_RS08680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CTW00_RS08685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CTW00_RS08705	COG0356	it plays a direct role in the translocation of protons across the membrane
CTW00_RS08715	COG0297	glycogen (starch) synthase activity
CTW00_RS08720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CTW00_RS08725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CTW00_RS08735	COG1523	belongs to the glycosyl hydrolase 13 family
CTW00_RS08740	COG1597	lipid kinase activity
CTW00_RS08745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CTW00_RS08750	COG4708	membrane
CTW00_RS08775	COG1131	(ABC) transporter
CTW00_RS08815	COG0148	phosphopyruvate hydratase activity
CTW00_RS08835	COG0560	Phosphoserine phosphatase
CTW00_RS08840	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CTW00_RS08855	COG0772	Belongs to the SEDS family
CTW00_RS08870	COG0335	large ribosomal subunit rRNA binding
CTW00_RS08875	COG0038	chloride channel
CTW00_RS08885	COG0716	FMN binding
CTW00_RS08895	COG0625	glutathione transferase activity
CTW00_RS08905	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CTW00_RS08910	COG2153	protein acetylation
CTW00_RS08915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CTW00_RS08955	COG1660	Displays ATPase and GTPase activities
CTW00_RS08965	COG0017	Asparaginyl-tRNA synthetase
CTW00_RS08970	COG0436	Aminotransferase
CTW00_RS08975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTW00_RS08975	COG1199	ATP-dependent helicase activity
CTW00_RS08985	COG2177	Part of the ABC transporter FtsEX involved in
CTW00_RS08990	COG2884	Cell division ATP-binding protein ftsE
CTW00_RS09000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTW00_RS09005	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CTW00_RS09015	COG0584	glycerophosphoryl diester phosphodiesterase
CTW00_RS09035	COG1078	dGTPase activity
CTW00_RS09070	COG1595	DNA-templated transcription, initiation
CTW00_RS09075	COG0772	Belongs to the SEDS family
CTW00_RS09085	COG1164	Oligoendopeptidase f
CTW00_RS09105	COG3859	Proton-coupled thiamine transporter YuaJ
CTW00_RS09110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTW00_RS09115	COG3304	Inner membrane component domain
CTW00_RS09120	COG0406	alpha-ribazole phosphatase activity
CTW00_RS09160	COG0285	dihydrofolate synthase activity
CTW00_RS09165	COG2986	histidine ammonia-lyase
CTW00_RS09170	COG0531	amino acid
CTW00_RS09185	COG3404	Formiminotransferase-cyclodeaminase
CTW00_RS09200	COG1228	amidohydrolase
CTW00_RS09210	COG4166	transmembrane transport
CTW00_RS09215	COG4443	Transcriptional Coactivator p15 (PC4)
CTW00_RS09220	COG0826	peptidase U32
CTW00_RS09260	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CTW00_RS09280	COG2183	response to ionizing radiation
CTW00_RS09290	COG0704	Plays a role in the regulation of phosphate uptake
CTW00_RS09295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTW00_RS09300	COG0581	inorganic phosphate transmembrane transporter activity
CTW00_RS09305	COG0573	inorganic phosphate transmembrane transporter activity
CTW00_RS09310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTW00_RS09315	COG5002	protein histidine kinase activity
CTW00_RS09320	COG0745	RESPONSE REGULATOR receiver
CTW00_RS09325	COG0346	lactoylglutathione lyase activity
CTW00_RS09335	COG0701	Predicted permease
CTW00_RS09340	COG3689	TIGRFAM TIGR03943 family protein
CTW00_RS09345	COG1090	epimerase
CTW00_RS09350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CTW00_RS09360	COG1447	Phosphotransferase system cellobiose-specific component IIA
CTW00_RS09370	COG3711	transcriptional antiterminator
CTW00_RS09370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTW00_RS09380	COG2723	6-phospho-beta-galactosidase activity
CTW00_RS09390	COG0552	protein localization to endoplasmic reticulum
CTW00_RS09395	COG0561	phosphatase activity
CTW00_RS09400	COG0561	phosphatase activity
CTW00_RS09425	COG1196	nuclear chromosome segregation
CTW00_RS09430	COG0571	ribonuclease III activity
CTW00_RS09435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CTW00_RS09440	COG5002	protein histidine kinase activity
CTW00_RS09445	COG0745	RESPONSE REGULATOR receiver
CTW00_RS09450	COG1126	abc transporter atp-binding protein
CTW00_RS09455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTW00_RS09460	COG0765	amino acid transport
CTW00_RS09465	COG0765	amino acid transport
CTW00_RS09475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CTW00_RS09480	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CTW00_RS09485	COG1461	Dihydroxyacetone kinase
CTW00_RS09490	COG2376	Dihydroxyacetone kinase
CTW00_RS09500	COG2376	Dihydroxyacetone kinase
CTW00_RS09510	COG4152	abc transporter atp-binding protein
CTW00_RS09525	COG1131	(ABC) transporter
CTW00_RS09535	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CTW00_RS09540	COG0438	transferase activity, transferring glycosyl groups
CTW00_RS09550	COG1609	Transcriptional regulator
CTW00_RS09555	COG0006	proline dipeptidase activity
CTW00_RS09565	COG0778	Nitroreductase
CTW00_RS09570	COG0346	lactoylglutathione lyase activity
CTW00_RS09575	COG0463	Glycosyl transferase, family 2
CTW00_RS09605	COG0557	exoribonuclease II activity
CTW00_RS09620	COG0433	COG0433 Predicted ATPase
CTW00_RS09625	COG2364	Membrane
CTW00_RS09655	COG1131	(ABC) transporter
CTW00_RS09685	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CTW00_RS09690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CTW00_RS09695	COG1573	uracil-dna glycosylase
CTW00_RS09700	COG1702	phosphate starvation-inducible protein PhoH
CTW00_RS09710	COG3328	transposase activity
CTW00_RS09720	COG4479	Belongs to the UPF0346 family
CTW00_RS09725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CTW00_RS09735	COG0233	cytoplasmic translational termination
CTW00_RS09745	COG0081	regulation of translation
CTW00_RS09750	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CTW00_RS09755	COG2826	transposase and inactivated derivatives, IS30 family
CTW00_RS09795	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTW00_RS09805	COG0494	nUDIX hydrolase
CTW00_RS09810	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CTW00_RS09815	COG0673	inositol 2-dehydrogenase activity
CTW00_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
CTW00_RS09850	COG1114	Component of the transport system for branched-chain amino acids
CTW00_RS09890	COG1304	FMN binding
CTW00_RS09895	COG1620	l-lactate permease
CTW00_RS09905	COG0640	Transcriptional regulator
CTW00_RS09910	COG0708	Exodeoxyribonuclease III
CTW00_RS09940	COG1393	Belongs to the ArsC family
CTW00_RS09945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTW00_RS09950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTW00_RS09960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CTW00_RS09980	COG1774	PSP1 C-terminal conserved region
CTW00_RS09985	COG0470	DNA polymerase III
CTW00_RS09990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CTW00_RS09995	COG0517	IMP dehydrogenase activity
CTW00_RS10015	COG0559	Belongs to the binding-protein-dependent transport system permease family
CTW00_RS10025	COG4471	UPF0298 protein
CTW00_RS10050	COG2244	polysaccharide biosynthetic process
CTW00_RS10070	COG1120	ATPase activity
CTW00_RS10075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CTW00_RS10080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTW00_RS10085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTW00_RS10100	COG1227	inorganic diphosphatase activity
CTW00_RS10110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CTW00_RS10115	COG1253	flavin adenine dinucleotide binding
CTW00_RS10125	COG1605	Chorismate mutase
CTW00_RS10125	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CTW00_RS10140	COG1131	(ABC) transporter
CTW00_RS10145	COG1242	4 iron, 4 sulfur cluster binding
CTW00_RS10150	COG0671	phosphoesterase, PA-phosphatase related
CTW00_RS10155	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CTW00_RS10165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CTW00_RS10175	COG1192	Involved in chromosome partitioning
CTW00_RS10200	COG0484	heat shock protein binding