locus-tag	class	description
SI82_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SI82_RS00010	COG0592	DNA-directed DNA polymerase activity
SI82_RS00020	COG0012	GTP binding
SI82_RS00025	COG0193	aminoacyl-tRNA hydrolase activity
SI82_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SI82_RS00035	COG2244	polysaccharide biosynthetic process
SI82_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SI82_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SI82_RS00100	COG0531	amino acid
SI82_RS00110	COG2801	Transposase and inactivated derivatives
SI82_RS00115	COG3328	transposase activity
SI82_RS00130	COG2801	Transposase and inactivated derivatives
SI82_RS00250	COG3942	CHAP domain
SI82_RS00260	COG0436	Aminotransferase
SI82_RS00270	COG0416	fatty acid biosynthetic process
SI82_RS00275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SI82_RS00280	COG2188	Transcriptional regulator
SI82_RS00285	COG2222	sugar isomerase
SI82_RS00305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SI82_RS00310	COG3715	PTS system
SI82_RS00315	COG3716	PTS system mannose fructose sorbose family IID component
SI82_RS00320	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SI82_RS00320	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SI82_RS00340	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SI82_RS00350	COG2255	four-way junction helicase activity
SI82_RS00355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SI82_RS00365	COG2755	lipolytic protein G-D-S-L family
SI82_RS00365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SI82_RS00370	COG1454	alcohol dehydrogenase
SI82_RS00370	COG1012	belongs to the aldehyde dehydrogenase family
SI82_RS00380	COG0534	Mate efflux family protein
SI82_RS00390	COG0051	transcription antitermination factor activity, RNA binding
SI82_RS00395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SI82_RS00400	COG0088	Forms part of the polypeptide exit tunnel
SI82_RS00405	COG0089	rRNA binding
SI82_RS00425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SI82_RS00490	COG0200	Binds to the 23S rRNA
SI82_RS00495	COG0201	protein transport
SI82_RS00500	COG0563	adenylate kinase activity
SI82_RS00510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SI82_RS00645	COG2963	transposase activity
SI82_RS00650	COG2801	Transposase and inactivated derivatives
SI82_RS00705	COG1064	alcohol dehydrogenase
SI82_RS00720	COG2963	transposase activity
SI82_RS00725	COG2801	Transposase and inactivated derivatives
SI82_RS00745	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SI82_RS00760	COG1252	NADH dehydrogenase
SI82_RS00765	COG1271	oxidase subunit
SI82_RS00770	COG1294	oxidase, subunit
SI82_RS00775	COG4988	ABC transporter
SI82_RS00780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SI82_RS00785	COG0142	geranyltranstransferase activity
SI82_RS00790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SI82_RS00800	COG1121	(ABC) transporter
SI82_RS00805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SI82_RS00815	COG4499	WXG100 protein secretion system (Wss), protein YukC
SI82_RS00815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SI82_RS00825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SI82_RS00835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SI82_RS00840	COG1459	type II secretion system
SI82_RS00845	COG4537	Required for transformation and DNA binding
SI82_RS00870	COG0827	DNA restriction-modification system
SI82_RS00895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SI82_RS00900	COG1363	Peptidase, m42
SI82_RS00910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SI82_RS00915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SI82_RS00940	COG4120	Belongs to the binding-protein-dependent transport system permease family
SI82_RS00945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SI82_RS00950	COG1428	Deoxynucleoside kinase
SI82_RS00955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SI82_RS00960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SI82_RS01000	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SI82_RS01015	COG1349	DNA-binding transcription factor activity
SI82_RS01020	COG1882	Formate acetyltransferase
SI82_RS01055	COG3328	transposase activity
SI82_RS01090	COG2017	converts alpha-aldose to the beta-anomer
SI82_RS01095	COG0745	RESPONSE REGULATOR receiver
SI82_RS01100	COG5002	protein histidine kinase activity
SI82_RS01110	COG4808	Protein conserved in bacteria
SI82_RS01125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SI82_RS01145	COG1914	H( )-stimulated, divalent metal cation uptake system
SI82_RS01150	COG1902	pentaerythritol trinitrate reductase activity
SI82_RS01155	COG3711	transcriptional antiterminator
SI82_RS01155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SI82_RS01160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SI82_RS01165	COG3775	system Galactitol-specific IIC component
SI82_RS01170	COG3414	Phosphotransferase system galactitol-specific IIB component
SI82_RS01220	COG3443	Belongs to the bacterial solute-binding protein 9 family
SI82_RS01220	COG0803	Belongs to the bacterial solute-binding protein 9 family
SI82_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
SI82_RS01265	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SI82_RS01270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SI82_RS01275	COG3715	PTS system
SI82_RS01280	COG3716	PTS system mannose fructose sorbose family IID component
SI82_RS01290	COG1609	Transcriptional regulator
SI82_RS01295	COG5492	domain, Protein
SI82_RS01300	COG1131	(ABC) transporter
SI82_RS01310	COG2203	Gaf domain
SI82_RS01310	COG4585	Histidine kinase
SI82_RS01315	COG2197	response regulator
SI82_RS01320	COG0789	Transcriptional regulator
SI82_RS01320	COG4978	Transcriptional regulator
SI82_RS01335	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SI82_RS01340	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SI82_RS01345	COG1012	belongs to the aldehyde dehydrogenase family
SI82_RS01350	COG1882	Formate acetyltransferase
SI82_RS01355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SI82_RS01370	COG1454	alcohol dehydrogenase
SI82_RS01370	COG1012	belongs to the aldehyde dehydrogenase family
SI82_RS01385	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SI82_RS01400	COG1012	belongs to the aldehyde dehydrogenase family
SI82_RS01400	COG1454	alcohol dehydrogenase
SI82_RS01405	COG4869	propanediol catabolic process
SI82_RS01435	COG0577	efflux transmembrane transporter activity
SI82_RS01440	COG1136	(ABC) transporter
SI82_RS01445	COG0745	RESPONSE REGULATOR receiver
SI82_RS01450	COG5002	protein histidine kinase activity
SI82_RS01460	COG1396	sequence-specific DNA binding
SI82_RS01505	COG3328	transposase activity
SI82_RS01510	COG1131	(ABC) transporter
SI82_RS01525	COG3328	transposase activity
SI82_RS01545	COG2801	Transposase and inactivated derivatives
SI82_RS01550	COG2801	Transposase and inactivated derivatives
SI82_RS01555	COG2963	transposase activity
SI82_RS01565	COG2963	transposase activity
SI82_RS01580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SI82_RS01585	COG0512	Glutamine amidotransferase of anthranilate synthase
SI82_RS01590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SI82_RS01595	COG0154	amidase activity
SI82_RS01610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SI82_RS01625	COG1263	PTS System
SI82_RS01625	COG2190	(PTS) system
SI82_RS01625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SI82_RS01635	COG1363	Peptidase, m42
SI82_RS01645	COG0737	Belongs to the 5'-nucleotidase family
SI82_RS01675	COG3842	ATPase activity
SI82_RS01695	COG1609	Transcriptional regulator
SI82_RS01700	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SI82_RS01705	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SI82_RS01710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SI82_RS01720	COG1862	Preprotein translocase
SI82_RS01730	COG4589	Belongs to the CDS family
SI82_RS01740	COG0442	prolyl-tRNA aminoacylation
SI82_RS01780	COG0242	peptide deformylase activity
SI82_RS01795	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SI82_RS01810	COG1045	serine acetyltransferase
SI82_RS01820	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SI82_RS01850	COG0383	alpha-mannosidase activity
SI82_RS01865	COG4209	transmembrane transport
SI82_RS01870	COG0395	ABC-type sugar transport system, permease component
SI82_RS01875	COG1653	transport
SI82_RS01885	COG2972	Histidine kinase
SI82_RS01890	COG2207	Transcriptional regulator
SI82_RS01890	COG4753	response regulator
SI82_RS01895	COG2723	6-phospho-beta-galactosidase activity
SI82_RS01915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SI82_RS01940	COG2826	transposase and inactivated derivatives, IS30 family
SI82_RS01945	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SI82_RS01950	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SI82_RS01985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SI82_RS02030	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
SI82_RS02045	COG2851	Citrate transporter
SI82_RS02055	COG0511	ligase activity, forming carbon-carbon bonds
SI82_RS02060	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
SI82_RS02070	COG3052	prosthetic group binding
SI82_RS02095	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SI82_RS02105	COG0392	lysyltransferase activity
SI82_RS02105	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SI82_RS02120	COG1122	ATPase activity
SI82_RS02125	COG4720	Psort location CytoplasmicMembrane, score
SI82_RS02165	COG0527	aspartate kinase activity
SI82_RS02170	COG0101	tRNA pseudouridine synthase activity
SI82_RS02175	COG0351	phosphomethylpyrimidine kinase
SI82_RS02175	COG0352	thiamine-phosphate diphosphorylase activity
SI82_RS02180	COG4720	Psort location CytoplasmicMembrane, score
SI82_RS02190	COG0668	transmembrane transport
SI82_RS02195	COG0544	peptidyl-prolyl cis-trans isomerase activity
SI82_RS02200	COG0546	phosphoglycolate phosphatase activity
SI82_RS02210	COG3343	RNA polymerase activity
SI82_RS02220	COG3275	phosphorelay sensor kinase activity
SI82_RS02225	COG3279	Response regulator of the LytR AlgR family
SI82_RS02235	COG1346	cytolysis
SI82_RS02280	COG1126	abc transporter atp-binding protein
SI82_RS02285	COG0765	amino acid transport
SI82_RS02300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SI82_RS02310	COG0719	Fe-S assembly protein
SI82_RS02315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SI82_RS02325	COG0719	Fe-S assembly protein
SI82_RS02335	COG2963	transposase activity
SI82_RS02340	COG2801	Transposase and inactivated derivatives
SI82_RS02345	COG1686	Belongs to the peptidase S11 family
SI82_RS02350	COG1686	Belongs to the peptidase S11 family
SI82_RS02355	COG4166	transmembrane transport
SI82_RS02360	COG0601	transmembrane transport
SI82_RS02365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SI82_RS02370	COG0444	Belongs to the ABC transporter superfamily
SI82_RS02450	COG2137	regulation of response to DNA damage stimulus
SI82_RS02460	COG1216	Glycosyl transferase, family 2
SI82_RS02460	COG1442	glycosyl transferase family 8
SI82_RS02475	COG1442	glycosyl transferase family 8
SI82_RS02475	COG1216	Glycosyl transferase, family 2
SI82_RS02480	COG1442	glycosyl transferase family 8
SI82_RS02505	COG1073	alpha beta
SI82_RS02540	COG3328	transposase activity
SI82_RS02560	COG1131	(ABC) transporter
SI82_RS02565	COG2207	Transcriptional regulator
SI82_RS02575	COG1175	transmembrane transport
SI82_RS02580	COG0395	ABC-type sugar transport system, permease component
SI82_RS02595	COG1247	-acetyltransferase
SI82_RS02615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SI82_RS02620	COG0586	Pfam SNARE associated Golgi protein
SI82_RS02625	COG1668	transmembrane transport
SI82_RS02630	COG4152	abc transporter atp-binding protein
SI82_RS02665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SI82_RS02715	COG3591	Belongs to the peptidase S1B family
SI82_RS02740	COG2963	transposase activity
SI82_RS02745	COG2801	Transposase and inactivated derivatives
SI82_RS02755	COG2972	Histidine kinase
SI82_RS02760	COG4753	response regulator
SI82_RS02760	COG2207	Transcriptional regulator
SI82_RS02765	COG1840	ABC-type Fe3 transport system, periplasmic component
SI82_RS02770	COG3842	ATPase activity
SI82_RS02775	COG1178	ABC-type Fe3 transport system permease component
SI82_RS02780	COG0673	inositol 2-dehydrogenase activity
SI82_RS02810	COG0454	-acetyltransferase
SI82_RS02820	COG1288	antiporter activity
SI82_RS02825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SI82_RS02830	COG0549	Belongs to the carbamate kinase family
SI82_RS02840	COG0742	ribosomal rna small subunit methyltransferase
SI82_RS02845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SI82_RS02855	COG1609	Transcriptional regulator
SI82_RS02860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SI82_RS02865	COG1869	D-ribose catabolic process
SI82_RS02875	COG1172	Belongs to the binding-protein-dependent transport system permease family
SI82_RS02880	COG1879	ABC-type sugar transport system periplasmic component
SI82_RS02885	COG0737	Belongs to the 5'-nucleotidase family
SI82_RS02890	COG4470	Protein conserved in bacteria
SI82_RS02895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SI82_RS02905	COG1132	(ABC) transporter
SI82_RS02910	COG1132	(ABC) transporter
SI82_RS02920	COG1940	carbohydrate kinase activity
SI82_RS02925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SI82_RS02930	COG1217	gtp-binding protein TYPA
SI82_RS02940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SI82_RS02945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SI82_RS02965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SI82_RS02970	COG1799	cell septum assembly
SI82_RS02985	COG3599	regulation of cell shape
SI82_RS03005	COG0542	response to heat
SI82_RS03010	COG4703	Protein of unknown function (DUF1797)
SI82_RS03015	COG0765	amino acid transport
SI82_RS03020	COG1126	abc transporter atp-binding protein
SI82_RS03025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SI82_RS03045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SI82_RS03050	COG1438	arginine binding
SI82_RS03055	COG0497	DNA recombination
SI82_RS03065	COG2801	Transposase and inactivated derivatives
SI82_RS03075	COG2755	lipolytic protein G-D-S-L family
SI82_RS03090	COG2217	Heavy metal translocating P-type atpase
SI82_RS03100	COG0167	dihydroorotate dehydrogenase activity
SI82_RS03110	COG1827	regulation of RNA biosynthetic process
SI82_RS03120	COG2116	formate transmembrane transporter activity
SI82_RS03125	COG0768	penicillin binding
SI82_RS03130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SI82_RS03135	COG1181	Belongs to the D-alanine--D-alanine ligase family
SI82_RS03140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SI82_RS03170	COG0561	phosphatase activity
SI82_RS03175	COG0513	Belongs to the DEAD box helicase family
SI82_RS03190	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SI82_RS03195	COG0204	Acyl-transferase
SI82_RS03200	COG1596	polysaccharide export
SI82_RS03200	COG1555	photosystem II stabilization
SI82_RS03205	COG2333	competence protein COMEC
SI82_RS03205	COG0658	competence protein
SI82_RS03240	COG1187	pseudouridine synthase activity
SI82_RS03250	COG3328	transposase activity
SI82_RS03280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SI82_RS03285	COG4122	O-methyltransferase activity
SI82_RS03290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SI82_RS03310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SI82_RS03315	COG0436	Aminotransferase
SI82_RS03320	COG2801	Transposase and inactivated derivatives
SI82_RS03340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SI82_RS03345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SI82_RS03350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SI82_RS03370	COG0726	polysaccharide deacetylase
SI82_RS03375	COG0513	Belongs to the DEAD box helicase family
SI82_RS03380	COG0572	uridine kinase
SI82_RS03395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SI82_RS03415	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SI82_RS03425	COG2211	Major facilitator Superfamily
SI82_RS03430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SI82_RS03435	COG2186	Transcriptional regulator
SI82_RS03440	COG0800	Aldolase
SI82_RS03450	COG1312	Catalyzes the dehydration of D-mannonate
SI82_RS03455	COG1028	Short-chain dehydrogenase reductase Sdr
SI82_RS03480	COG4109	DRTGG domain
SI82_RS03485	COG0024	Methionine aminopeptidase
SI82_RS03545	COG2801	Transposase and inactivated derivatives
SI82_RS03550	COG2963	transposase activity
SI82_RS03555	COG3328	transposase activity
SI82_RS03570	COG1136	(ABC) transporter
SI82_RS03570	COG0577	efflux transmembrane transporter activity
SI82_RS03580	COG0584	glycerophosphoryl diester phosphodiesterase
SI82_RS03595	COG3328	transposase activity
SI82_RS03605	COG0318	PFAM AMP-dependent synthetase and ligase
SI82_RS03610	COG1960	acyl-CoA dehydrogenase activity
SI82_RS03615	COG0427	acetyl-CoA hydrolase
SI82_RS03620	COG1024	Enoyl-CoA hydratase
SI82_RS03620	COG1250	3-hydroxyacyl-CoA dehydrogenase
SI82_RS03625	COG0183	Belongs to the thiolase family
SI82_RS03630	COG0583	DNA-binding transcription factor activity
SI82_RS03635	COG2050	protein possibly involved in aromatic compounds catabolism
SI82_RS03640	COG4619	ABC transporter
SI82_RS03645	COG0390	transport system, permease component
SI82_RS03650	COG4868	Belongs to the UPF0371 family
SI82_RS03655	COG2814	Major facilitator Superfamily
SI82_RS03670	COG1187	pseudouridine synthase activity
SI82_RS03675	COG0598	Magnesium transport protein CorA
SI82_RS03680	COG1132	(ABC) transporter
SI82_RS03690	COG2309	aminopeptidase activity
SI82_RS03695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SI82_RS03710	COG0488	(ABC) transporter
SI82_RS03715	COG1126	abc transporter atp-binding protein
SI82_RS03725	COG0556	nucleotide-excision repair
SI82_RS03740	COG1696	Membrane protein involved in D-alanine export
SI82_RS03745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SI82_RS03750	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SI82_RS03755	COG2182	Extracellular solute-binding protein
SI82_RS03760	COG0366	Alpha amylase catalytic
SI82_RS03770	COG1175	transmembrane transport
SI82_RS03775	COG3833	ABC-type maltose transport systems, permease component
SI82_RS03795	COG3833	ABC-type maltose transport systems, permease component
SI82_RS03800	COG1175	transmembrane transport
SI82_RS03810	COG1609	Transcriptional regulator
SI82_RS03815	COG1640	4-alpha-glucanotransferase
SI82_RS03820	COG0058	SHG alpha-glucan phosphorylase activity
SI82_RS03830	COG1054	Belongs to the UPF0176 family
SI82_RS03850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SI82_RS03865	COG0300	oxidoreductase activity
SI82_RS03870	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SI82_RS03870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SI82_RS03875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SI82_RS03885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SI82_RS03890	COG2384	SAM-dependent methyltransferase
SI82_RS03905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SI82_RS03910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SI82_RS03920	COG1088	dTDP-glucose 4,6-dehydratase activity
SI82_RS03930	COG2706	6-phosphogluconolactonase activity
SI82_RS03935	COG1051	belongs to the nudix hydrolase family
SI82_RS03940	COG2801	Transposase and inactivated derivatives
SI82_RS03945	COG2963	transposase activity
SI82_RS03950	COG1051	belongs to the nudix hydrolase family
SI82_RS03955	COG0628	permease
SI82_RS03960	COG0457	Tetratricopeptide repeat
SI82_RS03965	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SI82_RS03980	COG3842	ATPase activity
SI82_RS04000	COG0488	(ABC) transporter
SI82_RS04010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SI82_RS04015	COG0508	dehydrogenase complex catalyzes the overall conversion of
SI82_RS04015	COG0022	dehydrogenase e1 component
SI82_RS04020	COG0508	dehydrogenase complex catalyzes the overall conversion of
SI82_RS04030	COG0095	Lipoate-protein ligase
SI82_RS04035	COG3442	glutamine amidotransferase
SI82_RS04040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SI82_RS04045	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SI82_RS04055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SI82_RS04065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SI82_RS04095	COG1518	maintenance of DNA repeat elements
SI82_RS04100	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SI82_RS04125	COG0481	GTPase activity
SI82_RS04135	COG1418	mRNA catabolic process
SI82_RS04150	COG0656	L-ascorbic acid biosynthetic process
SI82_RS04165	COG2259	Doxx family
SI82_RS04170	COG1011	Hydrolase
SI82_RS04175	COG1012	belongs to the aldehyde dehydrogenase family
SI82_RS04180	COG0322	excinuclease ABC activity
SI82_RS04200	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SI82_RS04210	COG1393	Belongs to the ArsC family
SI82_RS04220	COG0813	purine-nucleoside phosphorylase activity
SI82_RS04230	COG0583	DNA-binding transcription factor activity
SI82_RS04235	COG1316	TRANSCRIPTIONal
SI82_RS04260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SI82_RS04270	COG0438	transferase activity, transferring glycosyl groups
SI82_RS04270	COG4641	Protein conserved in bacteria
SI82_RS04275	COG0110	maltose O-acetyltransferase activity
SI82_RS04340	COG1881	PFAM PEBP family protein
SI82_RS04350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SI82_RS04355	COG0765	amino acid transport
SI82_RS04360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SI82_RS04365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SI82_RS04375	COG0187	DNA topoisomerase II activity
SI82_RS04390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SI82_RS04410	COG0539	negative regulation of cytoplasmic translation
SI82_RS04435	COG1131	(ABC) transporter
SI82_RS04440	COG1725	Transcriptional regulator
SI82_RS04450	COG0205	6-phosphofructokinase activity
SI82_RS04455	COG0469	pyruvate kinase activity
SI82_RS04470	COG2213	PTS system mannitol-specific
SI82_RS04475	COG3711	transcriptional antiterminator
SI82_RS04480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SI82_RS04485	COG0246	Mannitol dehydrogenase
SI82_RS04490	COG2824	Alkylphosphonate utilization operon protein PhnA
SI82_RS04495	COG0765	amino acid transport
SI82_RS04500	COG1126	abc transporter atp-binding protein
SI82_RS04505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SI82_RS04515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SI82_RS04520	COG1115	amino acid carrier protein
SI82_RS04535	COG2261	transglycosylase associated protein
SI82_RS04580	COG1136	(ABC) transporter
SI82_RS04610	COG0196	riboflavin kinase activity
SI82_RS04620	COG4476	Belongs to the UPF0223 family
SI82_RS04625	COG0483	inositol monophosphate 1-phosphatase activity
SI82_RS04635	COG0573	inorganic phosphate transmembrane transporter activity
SI82_RS04640	COG0581	inorganic phosphate transmembrane transporter activity
SI82_RS04655	COG0704	Plays a role in the regulation of phosphate uptake
SI82_RS04665	COG0745	RESPONSE REGULATOR receiver
SI82_RS04670	COG5002	protein histidine kinase activity
SI82_RS04685	COG2813	Specifically methylates the guanine in position
SI82_RS04690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SI82_RS04695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SI82_RS04700	COG0295	cytidine deaminase activity
SI82_RS04705	COG1744	ABC transporter substrate-binding protein PnrA-like
SI82_RS04710	COG3845	ABC transporter
SI82_RS04715	COG4603	Belongs to the binding-protein-dependent transport system permease family
SI82_RS04720	COG1079	Belongs to the binding-protein-dependent transport system permease family
SI82_RS04735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SI82_RS04740	COG4684	Psort location CytoplasmicMembrane, score
SI82_RS04745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SI82_RS04750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SI82_RS04760	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SI82_RS04765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SI82_RS04770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SI82_RS04775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SI82_RS04780	COG1328	CTP reductase activity
SI82_RS04780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SI82_RS04785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SI82_RS04790	COG0488	(ABC) transporter
SI82_RS04815	COG1272	protein, Hemolysin III
SI82_RS04835	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SI82_RS04845	COG0110	maltose O-acetyltransferase activity
SI82_RS04850	COG0758	DNA mediated transformation
SI82_RS04855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SI82_RS04860	COG0583	DNA-binding transcription factor activity
SI82_RS04885	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SI82_RS04895	COG1136	(ABC) transporter
SI82_RS04900	COG0577	efflux transmembrane transporter activity
SI82_RS04905	COG0745	RESPONSE REGULATOR receiver
SI82_RS04910	COG2205	protein histidine kinase activity
SI82_RS04920	COG4974	Belongs to the 'phage' integrase family
SI82_RS04930	COG0515	serine threonine protein kinase
SI82_RS04930	COG2815	serine threonine protein kinase
SI82_RS04970	COG0662	Cupin 2, conserved barrel domain protein
SI82_RS04975	COG0673	inositol 2-dehydrogenase activity
SI82_RS04990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SI82_RS04995	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SI82_RS05000	COG2188	Transcriptional regulator
SI82_RS05030	COG3104	oligopeptide transport
SI82_RS05035	COG0386	Belongs to the glutathione peroxidase family
SI82_RS05055	COG3328	transposase activity
SI82_RS05065	COG0346	lactoylglutathione lyase activity
SI82_RS05070	COG3764	Sortase (surface protein transpeptidase)
SI82_RS05080	COG0039	L-malate dehydrogenase activity
SI82_RS05100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SI82_RS05105	COG3153	acetyltransferase
SI82_RS05110	COG0009	L-threonylcarbamoyladenylate synthase
SI82_RS05115	COG2890	protein-(glutamine-N5) methyltransferase activity
SI82_RS05120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SI82_RS05130	COG2826	transposase and inactivated derivatives, IS30 family
SI82_RS05160	COG2801	Transposase and inactivated derivatives
SI82_RS05165	COG2233	PERMEase
SI82_RS05175	COG0516	GMP reductase activity
SI82_RS05180	COG1174	glycine betaine transport
SI82_RS05185	COG0517	IMP dehydrogenase activity
SI82_RS05185	COG1125	glycine betaine transport
SI82_RS05200	COG4221	oxidoreductase activity
SI82_RS05205	COG0280	phosphate acetyltransferase
SI82_RS05210	COG0564	pseudouridine synthase activity
SI82_RS05220	COG2357	RelA SpoT domain protein
SI82_RS05235	COG1104	cysteine desulfurase activity
SI82_RS05255	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SI82_RS05265	COG0628	permease
SI82_RS05270	COG2723	6-phospho-beta-galactosidase activity
SI82_RS05285	COG2723	6-phospho-beta-galactosidase activity
SI82_RS05290	COG2207	Transcriptional regulator
SI82_RS05295	COG1263	PTS System
SI82_RS05295	COG2190	(PTS) system
SI82_RS05295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SI82_RS05320	COG3493	citrate carrier protein
SI82_RS05325	COG3290	protein histidine kinase activity
SI82_RS05330	COG4565	transcriptional regulatory protein
SI82_RS05340	COG1177	transmembrane transport
SI82_RS05345	COG1176	ABC-type spermidine putrescine transport system, permease component I
SI82_RS05355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SI82_RS05360	COG2826	transposase and inactivated derivatives, IS30 family
SI82_RS05365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SI82_RS05380	COG0302	gtp cyclohydrolase
SI82_RS05385	COG0285	dihydrofolate synthase activity
SI82_RS05390	COG0083	homoserine kinase activity
SI82_RS05405	COG3328	transposase activity
SI82_RS05440	COG2801	Transposase and inactivated derivatives
SI82_RS05465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SI82_RS05475	COG3425	synthase
SI82_RS05485	COG1304	FMN binding
SI82_RS05500	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SI82_RS05505	COG1132	(ABC) transporter
SI82_RS05510	COG1132	(ABC) transporter
SI82_RS05515	COG0737	Belongs to the 5'-nucleotidase family
SI82_RS05520	COG0242	peptide deformylase activity
SI82_RS05525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SI82_RS05545	COG0488	(ABC) transporter
SI82_RS05550	COG0617	tRNA 3'-terminal CCA addition
SI82_RS05555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SI82_RS05580	COG1705	Flagellar rod assembly protein muramidase FlgJ
SI82_RS05580	COG1388	LysM domain
SI82_RS05585	COG1388	LysM domain
SI82_RS05585	COG1705	Flagellar rod assembly protein muramidase FlgJ
SI82_RS05590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SI82_RS05590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SI82_RS05590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SI82_RS05595	COG1105	Belongs to the carbohydrate kinase PfkB family
SI82_RS05600	COG1349	DNA-binding transcription factor activity
SI82_RS05620	COG0336	Belongs to the RNA methyltransferase TrmD family
SI82_RS05625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SI82_RS05635	COG1837	Belongs to the UPF0109 family
SI82_RS05640	COG0228	four-way junction DNA binding
SI82_RS05650	COG0577	efflux transmembrane transporter activity
SI82_RS05655	COG1136	(ABC) transporter
SI82_RS05670	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SI82_RS05675	COG0564	pseudouridine synthase activity
SI82_RS05685	COG0583	DNA-binding transcription factor activity
SI82_RS05690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SI82_RS05730	COG1104	cysteine desulfurase activity
SI82_RS05740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SI82_RS05765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SI82_RS05770	COG1368	sulfuric ester hydrolase activity
SI82_RS05780	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SI82_RS05790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SI82_RS05825	COG1216	Glycosyl transferase, family 2
SI82_RS05825	COG1442	glycosyl transferase family 8
SI82_RS05840	COG0463	Glycosyl transferase, family 2
SI82_RS05875	COG0463	Glycosyl transferase, family 2
SI82_RS05890	COG2151	metal-sulfur cluster biosynthetic enzyme
SI82_RS05895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SI82_RS05905	COG1970	mechanosensitive ion channel activity
SI82_RS05915	COG1074	ATP-dependent DNA helicase activity
SI82_RS05925	COG2321	neutral zinc metallopeptidase
SI82_RS05930	COG1136	(ABC) transporter
SI82_RS05935	COG0577	efflux transmembrane transporter activity
SI82_RS05975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SI82_RS05980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SI82_RS05985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SI82_RS06005	COG0356	it plays a direct role in the translocation of protons across the membrane
SI82_RS06015	COG0297	glycogen (starch) synthase activity
SI82_RS06020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SI82_RS06025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SI82_RS06035	COG1523	belongs to the glycosyl hydrolase 13 family
SI82_RS06040	COG1597	lipid kinase activity
SI82_RS06045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SI82_RS06050	COG4708	membrane
SI82_RS06075	COG1131	(ABC) transporter
SI82_RS06110	COG0148	phosphopyruvate hydratase activity
SI82_RS06130	COG0560	Phosphoserine phosphatase
SI82_RS06135	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SI82_RS06150	COG0772	Belongs to the SEDS family
SI82_RS06165	COG0335	large ribosomal subunit rRNA binding
SI82_RS06170	COG0038	chloride channel
SI82_RS06180	COG0716	FMN binding
SI82_RS06190	COG0625	glutathione transferase activity
SI82_RS06200	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SI82_RS06205	COG2153	protein acetylation
SI82_RS06210	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SI82_RS06225	COG2826	transposase and inactivated derivatives, IS30 family
SI82_RS06255	COG1660	Displays ATPase and GTPase activities
SI82_RS06265	COG0017	Asparaginyl-tRNA synthetase
SI82_RS06270	COG0436	Aminotransferase
SI82_RS06275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SI82_RS06275	COG1199	ATP-dependent helicase activity
SI82_RS06285	COG2177	Part of the ABC transporter FtsEX involved in
SI82_RS06290	COG2884	Cell division ATP-binding protein ftsE
SI82_RS06295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SI82_RS06300	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SI82_RS06305	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SI82_RS06315	COG0584	glycerophosphoryl diester phosphodiesterase
SI82_RS06335	COG1078	dGTPase activity
SI82_RS06370	COG1595	DNA-templated transcription, initiation
SI82_RS06375	COG0772	Belongs to the SEDS family
SI82_RS06385	COG1164	Oligoendopeptidase f
SI82_RS06405	COG3859	Proton-coupled thiamine transporter YuaJ
SI82_RS06410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SI82_RS06415	COG3304	Inner membrane component domain
SI82_RS06420	COG0406	alpha-ribazole phosphatase activity
SI82_RS06460	COG0285	dihydrofolate synthase activity
SI82_RS06465	COG2986	histidine ammonia-lyase
SI82_RS06470	COG0531	amino acid
SI82_RS06485	COG3404	Formiminotransferase-cyclodeaminase
SI82_RS06500	COG1228	amidohydrolase
SI82_RS06510	COG4166	transmembrane transport
SI82_RS06515	COG4443	Transcriptional Coactivator p15 (PC4)
SI82_RS06520	COG0826	peptidase U32
SI82_RS06545	COG2826	transposase and inactivated derivatives, IS30 family
SI82_RS06565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SI82_RS06585	COG2183	response to ionizing radiation
SI82_RS06595	COG0704	Plays a role in the regulation of phosphate uptake
SI82_RS06600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SI82_RS06605	COG0581	inorganic phosphate transmembrane transporter activity
SI82_RS06610	COG0573	inorganic phosphate transmembrane transporter activity
SI82_RS06615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SI82_RS06620	COG5002	protein histidine kinase activity
SI82_RS06625	COG0745	RESPONSE REGULATOR receiver
SI82_RS06630	COG0346	lactoylglutathione lyase activity
SI82_RS06640	COG0701	Predicted permease
SI82_RS06645	COG3689	TIGRFAM TIGR03943 family protein
SI82_RS06650	COG1090	epimerase
SI82_RS06655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SI82_RS06665	COG1447	Phosphotransferase system cellobiose-specific component IIA
SI82_RS06675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SI82_RS06675	COG3711	transcriptional antiterminator
SI82_RS06685	COG2723	6-phospho-beta-galactosidase activity
SI82_RS06695	COG0552	protein localization to endoplasmic reticulum
SI82_RS06700	COG0561	phosphatase activity
SI82_RS06705	COG0561	phosphatase activity
SI82_RS06725	COG1196	nuclear chromosome segregation
SI82_RS06730	COG0571	ribonuclease III activity
SI82_RS06735	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SI82_RS06740	COG5002	protein histidine kinase activity
SI82_RS06745	COG0745	RESPONSE REGULATOR receiver
SI82_RS06750	COG1126	abc transporter atp-binding protein
SI82_RS06755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SI82_RS06760	COG0765	amino acid transport
SI82_RS06765	COG0765	amino acid transport
SI82_RS06775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SI82_RS06780	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SI82_RS06785	COG1461	Dihydroxyacetone kinase
SI82_RS06790	COG2376	Dihydroxyacetone kinase
SI82_RS06800	COG2376	Dihydroxyacetone kinase
SI82_RS06805	COG2963	transposase activity
SI82_RS06810	COG2801	Transposase and inactivated derivatives
SI82_RS06815	COG1131	(ABC) transporter
SI82_RS06830	COG1131	(ABC) transporter
SI82_RS06840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SI82_RS06845	COG0438	transferase activity, transferring glycosyl groups
SI82_RS06855	COG1609	Transcriptional regulator
SI82_RS06860	COG0006	proline dipeptidase activity
SI82_RS06870	COG0778	Nitroreductase
SI82_RS06875	COG0346	lactoylglutathione lyase activity
SI82_RS06880	COG0463	Glycosyl transferase, family 2
SI82_RS06910	COG0557	exoribonuclease II activity
SI82_RS06920	COG0433	COG0433 Predicted ATPase
SI82_RS06925	COG2364	Membrane
SI82_RS06955	COG1131	(ABC) transporter
SI82_RS06985	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SI82_RS06990	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SI82_RS06995	COG1573	uracil-dna glycosylase
SI82_RS07000	COG1702	phosphate starvation-inducible protein PhoH
SI82_RS07010	COG3328	transposase activity
SI82_RS07020	COG4479	Belongs to the UPF0346 family
SI82_RS07025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SI82_RS07035	COG0233	cytoplasmic translational termination
SI82_RS07045	COG0081	regulation of translation
SI82_RS07050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SI82_RS07055	COG2826	transposase and inactivated derivatives, IS30 family
SI82_RS07095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SI82_RS07105	COG0494	nUDIX hydrolase
SI82_RS07110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SI82_RS07115	COG0673	inositol 2-dehydrogenase activity
SI82_RS07120	COG1028	Short-chain dehydrogenase reductase Sdr
SI82_RS07130	COG0582	viral genome integration into host DNA
SI82_RS07150	COG1114	Component of the transport system for branched-chain amino acids
SI82_RS07180	COG1304	FMN binding
SI82_RS07185	COG1620	l-lactate permease
SI82_RS07195	COG0640	Transcriptional regulator
SI82_RS07200	COG0708	Exodeoxyribonuclease III
SI82_RS07230	COG1393	Belongs to the ArsC family
SI82_RS07235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SI82_RS07240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SI82_RS07250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SI82_RS07270	COG1774	PSP1 C-terminal conserved region
SI82_RS07275	COG0470	DNA polymerase III
SI82_RS07280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SI82_RS07285	COG0517	IMP dehydrogenase activity
SI82_RS07305	COG0559	Belongs to the binding-protein-dependent transport system permease family
SI82_RS07315	COG4471	UPF0298 protein
SI82_RS07340	COG2244	polysaccharide biosynthetic process
SI82_RS07360	COG1120	ATPase activity
SI82_RS07365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SI82_RS07370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SI82_RS07375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SI82_RS07390	COG1227	inorganic diphosphatase activity
SI82_RS07400	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SI82_RS07405	COG1253	flavin adenine dinucleotide binding
SI82_RS07415	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SI82_RS07415	COG1605	Chorismate mutase
SI82_RS07430	COG1131	(ABC) transporter
SI82_RS07435	COG1242	4 iron, 4 sulfur cluster binding
SI82_RS07440	COG0671	phosphoesterase, PA-phosphatase related
SI82_RS07445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SI82_RS07455	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SI82_RS07460	COG1187	pseudouridine synthase activity
SI82_RS07470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SI82_RS07495	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SI82_RS07500	COG3763	UPF0154 protein
SI82_RS07520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SI82_RS07525	COG1254	Belongs to the acylphosphatase family
SI82_RS07540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SI82_RS07560	COG2826	transposase and inactivated derivatives, IS30 family
SI82_RS07590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SI82_RS07600	COG1484	DNA-dependent DNA replication
SI82_RS07610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SI82_RS07620	COG0745	RESPONSE REGULATOR receiver
SI82_RS07630	COG0501	Belongs to the peptidase M48B family
SI82_RS07635	COG1704	LemA family
SI82_RS07645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SI82_RS07650	COG0569	domain protein
SI82_RS07660	COG3328	transposase activity
SI82_RS07665	COG1114	Component of the transport system for branched-chain amino acids
SI82_RS07680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SI82_RS07685	COG1464	Belongs to the NlpA lipoprotein family
SI82_RS07690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SI82_RS07705	COG0789	Transcriptional regulator
SI82_RS07720	COG2226	methyltransferase
SI82_RS07725	COG0799	negative regulation of ribosome biogenesis
SI82_RS07730	COG1713	HD superfamily hydrolase involved in NAD metabolism
SI82_RS07740	COG1534	Rna-binding protein
SI82_RS07745	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SI82_RS07750	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SI82_RS07790	COG2801	Transposase and inactivated derivatives
SI82_RS07805	COG1040	competence protein
SI82_RS07810	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SI82_RS07815	COG1739	Uncharacterized protein family UPF0029
SI82_RS07830	COG1098	S1 RNA binding domain
SI82_RS07840	COG2197	response regulator
SI82_RS07845	COG4585	Histidine kinase
SI82_RS07855	COG0515	serine threonine protein kinase
SI82_RS07855	COG2815	serine threonine protein kinase
SI82_RS07865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SI82_RS07865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SI82_RS07875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SI82_RS07880	COG1758	RNA polymerase activity
SI82_RS07895	COG1854	S-ribosylhomocysteine lyase activity
SI82_RS07905	COG0116	Belongs to the methyltransferase superfamily
SI82_RS07920	COG4474	Belongs to the UPF0398 family
SI82_RS07925	COG3331	DNA recombination
SI82_RS07930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SI82_RS07935	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SI82_RS07940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SI82_RS07955	COG1113	amino acid transport
SI82_RS07960	COG0492	ferredoxin-NADP+ reductase activity
SI82_RS07970	COG1126	abc transporter atp-binding protein
SI82_RS07975	COG0765	amino acid transport
SI82_RS07980	COG0513	Belongs to the DEAD box helicase family
SI82_RS07985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SI82_RS07990	COG0768	penicillin binding
SI82_RS08000	COG0275	rRNA processing
SI82_RS08010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SI82_RS08020	COG1131	(ABC) transporter
SI82_RS08040	COG0446	pyridine nucleotide-disulphide oxidoreductase
SI82_RS08045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SI82_RS08070	COG0751	glycine-tRNA ligase activity
SI82_RS08080	COG1755	Isoprenylcysteine carboxyl methyltransferase
SI82_RS08085	COG0656	L-ascorbic acid biosynthetic process
SI82_RS08100	COG0561	phosphatase activity
SI82_RS08110	COG3250	beta-galactosidase activity
SI82_RS08145	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SI82_RS08150	COG0195	Participates in both transcription termination and antitermination
SI82_RS08160	COG1368	sulfuric ester hydrolase activity
SI82_RS08200	COG1131	(ABC) transporter
SI82_RS08205	COG0537	adenosine 5'-monophosphoramidase activity
SI82_RS08215	COG1316	TRANSCRIPTIONal
SI82_RS08225	COG0802	atpase or kinase
SI82_RS08230	COG2252	PERMEase
SI82_RS08235	COG0561	phosphatase activity
SI82_RS08245	COG3715	PTS system
SI82_RS08250	COG3716	PTS system mannose fructose sorbose family IID component
SI82_RS08265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SI82_RS08285	COG0439	Biotin carboxylase
SI82_RS08300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SI82_RS08305	COG1028	Short-chain dehydrogenase reductase Sdr
SI82_RS08310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SI82_RS08325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SI82_RS08335	COG1024	Enoyl-CoA hydratase
SI82_RS08340	COG0484	heat shock protein binding
SI82_RS08350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SI82_RS08355	COG1420	regulation of RNA biosynthetic process
SI82_RS08360	COG1388	LysM domain
SI82_RS08360	COG1705	Flagellar rod assembly protein muramidase FlgJ
SI82_RS08370	COG0588	phosphoglycerate mutase activity
SI82_RS08375	COG2848	UPF0210 protein
SI82_RS08380	COG3830	Belongs to the UPF0237 family
SI82_RS08385	COG2261	transglycosylase associated protein
SI82_RS08400	COG0154	amidase activity
SI82_RS08405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SI82_RS08410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SI82_RS08410	COG0574	Belongs to the PEP-utilizing enzyme family
SI82_RS08415	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SI82_RS08420	COG0517	IMP dehydrogenase activity
SI82_RS08425	COG1054	Belongs to the UPF0176 family
SI82_RS08440	COG1937	Protein conserved in bacteria
SI82_RS08445	COG1335	isochorismatase
SI82_RS08450	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SI82_RS08455	COG0436	Aminotransferase
SI82_RS08460	COG0589	response to stress
SI82_RS08465	COG0561	phosphatase activity
SI82_RS08475	COG0252	asparaginase activity
SI82_RS08480	COG4989	oxidoreductase activity
SI82_RS08485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SI82_RS08490	COG1129	ABC transporter
SI82_RS08505	COG1132	(ABC) transporter
SI82_RS08510	COG4988	ABC transporter
SI82_RS08515	COG1120	ATPase activity
SI82_RS08540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SI82_RS08545	COG0736	holo-[acyl-carrier-protein] synthase activity
SI82_RS08550	COG0653	protein targeting
SI82_RS08555	COG1482	cell wall glycoprotein biosynthetic process
SI82_RS08560	COG1940	carbohydrate kinase activity
SI82_RS08565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SI82_RS08565	COG2190	(PTS) system
SI82_RS08565	COG1263	PTS System
SI82_RS08570	COG1621	beta-fructofuranosidase activity
SI82_RS08575	COG1609	Transcriptional regulator
SI82_RS08580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SI82_RS08600	COG2131	deaminase
SI82_RS08605	COG0006	proline dipeptidase activity
SI82_RS08635	COG1368	sulfuric ester hydrolase activity
SI82_RS08660	COG1194	a g-specific adenine glycosylase
SI82_RS08670	COG3118	belongs to the thioredoxin family
SI82_RS08675	COG1193	negative regulation of DNA recombination
SI82_RS08690	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SI82_RS08695	COG0681	Belongs to the peptidase S26 family
SI82_RS08700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SI82_RS08715	COG1882	Formate acetyltransferase
SI82_RS08730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SI82_RS08745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SI82_RS08750	COG2936	dipeptidyl-peptidase activity
SI82_RS08765	COG3942	CHAP domain
SI82_RS08765	COG1705	Flagellar rod assembly protein muramidase FlgJ
SI82_RS08815	COG2801	Transposase and inactivated derivatives
SI82_RS08820	COG2963	transposase activity
SI82_RS08835	COG1476	TRANSCRIPTIONal
SI82_RS08870	COG0582	viral genome integration into host DNA
SI82_RS08900	COG2081	HI0933 family
SI82_RS08920	COG1214	PFAM Peptidase M22, glycoprotease
SI82_RS08925	COG5503	Protein of unknown function (DUF1447)
SI82_RS08935	COG4608	Belongs to the ABC transporter superfamily
SI82_RS08940	COG0444	Belongs to the ABC transporter superfamily
SI82_RS08945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SI82_RS08950	COG0601	transmembrane transport
SI82_RS08955	COG4166	transmembrane transport
SI82_RS08960	COG0174	glutamine synthetase
SI82_RS08965	COG0789	Transcriptional regulator
SI82_RS08980	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SI82_RS09010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SI82_RS09040	COG1288	antiporter activity
SI82_RS09045	COG0549	Belongs to the carbamate kinase family
SI82_RS09050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SI82_RS09055	COG4191	Histidine kinase
SI82_RS09060	COG0784	Response regulator, receiver
SI82_RS09065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SI82_RS09070	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SI82_RS09075	COG0084	hydrolase, TatD family'
SI82_RS09090	COG2801	Transposase and inactivated derivatives
SI82_RS09105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SI82_RS09120	COG0395	ABC-type sugar transport system, permease component
SI82_RS09145	COG0395	ABC-type sugar transport system, permease component
SI82_RS09150	COG1175	transmembrane transport
SI82_RS09185	COG3279	Response regulator of the LytR AlgR family
SI82_RS09195	COG1131	(ABC) transporter
SI82_RS09210	COG0594	ribonuclease P activity
SI82_RS09215	COG0165	Argininosuccinate lyase
SI82_RS09275	COG0756	dUTP diphosphatase activity
SI82_RS09280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SI82_RS09280	COG1263	PTS System
SI82_RS09285	COG0366	Alpha amylase catalytic
SI82_RS09295	COG1737	Transcriptional regulator
SI82_RS09300	COG2832	Protein of unknown function (DUF454)
SI82_RS09330	COG1132	(ABC) transporter
SI82_RS09335	COG1132	(ABC) transporter
SI82_RS09345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SI82_RS09350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SI82_RS09365	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SI82_RS09370	COG1215	transferase activity, transferring glycosyl groups
SI82_RS09375	COG1473	amidohydrolase
SI82_RS09385	COG0166	Belongs to the GPI family
SI82_RS09425	COG1234	tRNA 3'-trailer cleavage
SI82_RS09430	COG1268	BioY protein
SI82_RS09445	COG0343	queuine tRNA-ribosyltransferase activity
SI82_RS09455	COG0735	belongs to the Fur family
SI82_RS09460	COG1832	CoA-binding protein
SI82_RS09465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SI82_RS09465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SI82_RS09475	COG4175	Glycine betaine
SI82_RS09475	COG3448	diguanylate cyclase activity
SI82_RS09480	COG1597	lipid kinase activity
SI82_RS09490	COG0415	Belongs to the DNA photolyase family
SI82_RS09515	COG3775	system Galactitol-specific IIC component
SI82_RS09520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SI82_RS09530	COG1609	Transcriptional regulator
SI82_RS09540	COG3623	hexulose-6-phosphate isomerase
SI82_RS09550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SI82_RS09565	COG1929	Belongs to the glycerate kinase type-1 family
SI82_RS09575	COG2964	Protein conserved in bacteria
SI82_RS09580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SI82_RS09585	COG0626	cystathionine gamma-synthase activity
SI82_RS09590	COG0251	oxidation-reduction process
SI82_RS09600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SI82_RS09620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SI82_RS09635	COG0564	pseudouridine synthase activity
SI82_RS09660	COG0459	protein refolding
SI82_RS09670	COG0542	response to heat
SI82_RS09675	COG4463	regulation of RNA biosynthetic process
SI82_RS09690	COG0025	NhaP-type Na H and K H
SI82_RS09700	COG0450	alkyl hydroperoxide reductase
SI82_RS09720	COG3590	peptidase
SI82_RS09725	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SI82_RS09730	COG3959	Transketolase, thiamine diphosphate binding domain
SI82_RS09745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SI82_RS09750	COG0366	Alpha amylase catalytic
SI82_RS09755	COG1263	PTS System
SI82_RS09755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SI82_RS09760	COG2188	Transcriptional regulator
SI82_RS09770	COG0602	queuosine metabolic process
SI82_RS09780	COG0673	inositol 2-dehydrogenase activity
SI82_RS09785	COG1328	CTP reductase activity
SI82_RS09810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SI82_RS09815	COG4472	Bacterial protein of unknown function (DUF965)
SI82_RS09820	COG1393	Belongs to the ArsC family
SI82_RS09825	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SI82_RS09835	COG0519	Catalyzes the synthesis of GMP from XMP
SI82_RS09850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SI82_RS09870	COG0018	arginyl-trna synthetase
SI82_RS09875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SI82_RS09885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SI82_RS09915	COG2801	Transposase and inactivated derivatives
SI82_RS09930	COG5002	protein histidine kinase activity
SI82_RS09970	COG3759	membrane
SI82_RS09980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SI82_RS09990	COG0305	Participates in initiation and elongation during chromosome replication
SI82_RS09995	COG0359	binds to the 23S rRNA
SI82_RS10020	COG1760	l-serine dehydratase
SI82_RS10025	COG1760	l-serine dehydratase
SI82_RS10035	COG0741	lytic transglycosylase activity
SI82_RS10055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SI82_RS10065	COG0612	Peptidase, M16
SI82_RS10070	COG0612	Peptidase, M16
SI82_RS10100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SI82_RS10105	COG0488	(ABC) transporter
SI82_RS10135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SI82_RS10140	COG1475	DNA binding
SI82_RS10165	COG1523	belongs to the glycosyl hydrolase 13 family
SI82_RS10170	COG1523	belongs to the glycosyl hydrolase 13 family