locus-tag	class	description
SCIM_RS00010	COG0592	DNA-directed DNA polymerase activity
SCIM_RS00025	COG0012	GTP binding
SCIM_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
SCIM_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SCIM_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SCIM_RS00055	COG0037	tRNA processing
SCIM_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SCIM_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SCIM_RS00185	COG1792	Involved in formation and maintenance of cell shape
SCIM_RS00195	COG3942	CHAP domain
SCIM_RS00200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SCIM_RS00205	COG0436	Aminotransferase
SCIM_RS00210	COG1381	Involved in DNA repair and RecF pathway recombination
SCIM_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCIM_RS00225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SCIM_RS00230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SCIM_RS00240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SCIM_RS00245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SCIM_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SCIM_RS00260	COG0138	bifunctional purine biosynthesis protein purh
SCIM_RS00265	COG3942	CHAP domain
SCIM_RS00285	COG0151	Belongs to the GarS family
SCIM_RS00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SCIM_RS00340	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SCIM_RS00355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCIM_RS00365	COG3716	PTS system mannose fructose sorbose family IID component
SCIM_RS00375	COG2222	sugar isomerase
SCIM_RS00395	COG2255	four-way junction helicase activity
SCIM_RS00420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SCIM_RS00435	COG1012	belongs to the aldehyde dehydrogenase family
SCIM_RS00435	COG1454	alcohol dehydrogenase
SCIM_RS00440	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SCIM_RS00450	COG1175	transmembrane transport
SCIM_RS00455	COG0395	ABC-type sugar transport system, permease component
SCIM_RS00460	COG2731	YhcH YjgK YiaL family protein
SCIM_RS00470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCIM_RS00490	COG1263	PTS System
SCIM_RS00490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCIM_RS00495	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SCIM_RS00510	COG1269	ATP hydrolysis coupled proton transport
SCIM_RS00515	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SCIM_RS00525	COG1527	subunit (C
SCIM_RS00535	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SCIM_RS00540	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
SCIM_RS00545	COG1394	ATPase activity, coupled to movement of substances
SCIM_RS00570	COG1388	LysM domain
SCIM_RS00570	COG4932	domain protein
SCIM_RS00585	COG1846	Transcriptional regulator
SCIM_RS00590	COG1121	(ABC) transporter
SCIM_RS00595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SCIM_RS00600	COG0803	Belongs to the bacterial solute-binding protein 9 family
SCIM_RS00600	COG3443	Belongs to the bacterial solute-binding protein 9 family
SCIM_RS00620	COG0564	pseudouridine synthase activity
SCIM_RS00625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCIM_RS00650	COG0052	Belongs to the universal ribosomal protein uS2 family
SCIM_RS00655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SCIM_RS00665	COG4463	regulation of RNA biosynthetic process
SCIM_RS00680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SCIM_RS00685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SCIM_RS00705	COG1396	sequence-specific DNA binding
SCIM_RS00730	COG1131	(ABC) transporter
SCIM_RS00755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SCIM_RS00790	COG1132	(ABC) transporter
SCIM_RS00795	COG1132	(ABC) transporter
SCIM_RS00810	COG1129	ABC transporter
SCIM_RS00820	COG0166	Belongs to the GPI family
SCIM_RS00830	COG0594	ribonuclease P activity
SCIM_RS00850	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SCIM_RS00855	COG0084	hydrolase, TatD family'
SCIM_RS00875	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SCIM_RS00890	COG1162	GTPase activity
SCIM_RS00900	COG1564	THIamine pyrophosphokinase
SCIM_RS00910	COG3481	metal-dependent phosphohydrolase, HD sub domain
SCIM_RS00915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SCIM_RS00920	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SCIM_RS00925	COG0049	tRNA binding
SCIM_RS00930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SCIM_RS00935	COG1131	(ABC) transporter
SCIM_RS00965	COG1214	PFAM Peptidase M22, glycoprotease
SCIM_RS00975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SCIM_RS01000	COG2814	Major facilitator Superfamily
SCIM_RS01010	COG0789	Transcriptional regulator
SCIM_RS01020	COG2081	HI0933 family
SCIM_RS01035	COG0584	glycerophosphoryl diester phosphodiesterase
SCIM_RS01040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SCIM_RS01045	COG2936	dipeptidyl-peptidase activity
SCIM_RS01050	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SCIM_RS01090	COG1304	FMN binding
SCIM_RS01100	COG3425	synthase
SCIM_RS01115	COG1882	Formate acetyltransferase
SCIM_RS01120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SCIM_RS01125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SCIM_RS01130	COG0681	Belongs to the peptidase S26 family
SCIM_RS01150	COG1193	negative regulation of DNA recombination
SCIM_RS01160	COG3118	belongs to the thioredoxin family
SCIM_RS01170	COG0583	DNA-binding transcription factor activity
SCIM_RS01180	COG0531	amino acid
SCIM_RS01185	COG0668	transmembrane transport
SCIM_RS01190	COG5504	Zn-dependent protease
SCIM_RS01200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SCIM_RS01205	COG0167	dihydroorotate dehydrogenase activity
SCIM_RS01210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCIM_RS01210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCIM_RS01215	COG0402	S-adenosylhomocysteine deaminase activity
SCIM_RS01230	COG1136	(ABC) transporter
SCIM_RS01235	COG1940	carbohydrate kinase activity
SCIM_RS01240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCIM_RS01255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCIM_RS01260	COG1447	Phosphotransferase system cellobiose-specific component IIA
SCIM_RS01265	COG1309	transcriptional regulator
SCIM_RS01290	COG0346	lactoylglutathione lyase activity
SCIM_RS01335	COG0745	RESPONSE REGULATOR receiver
SCIM_RS01340	COG5002	protein histidine kinase activity
SCIM_RS01355	COG0366	Alpha amylase catalytic
SCIM_RS01365	COG1122	ATPase activity
SCIM_RS01375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SCIM_RS01385	COG2134	cdp-diacylglycerol pyrophosphatase
SCIM_RS01485	COG0629	single-stranded DNA binding
SCIM_RS01490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SCIM_RS01510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SCIM_RS01520	COG0006	proline dipeptidase activity
SCIM_RS01525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SCIM_RS01570	COG0527	aspartate kinase activity
SCIM_RS01575	COG1024	Enoyl-CoA hydratase
SCIM_RS01585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SCIM_RS01595	COG2070	2-Nitropropane dioxygenase
SCIM_RS01600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SCIM_RS01605	COG1028	Short-chain dehydrogenase reductase Sdr
SCIM_RS01610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SCIM_RS01620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SCIM_RS01625	COG0439	Biotin carboxylase
SCIM_RS01630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SCIM_RS01635	COG0825	malonyl-CoA metabolic process
SCIM_RS01640	COG0586	Pfam SNARE associated Golgi protein
SCIM_RS01655	COG3716	PTS system mannose fructose sorbose family IID component
SCIM_RS01660	COG3715	PTS system
SCIM_RS01670	COG1064	alcohol dehydrogenase
SCIM_RS01675	COG0561	phosphatase activity
SCIM_RS01685	COG2252	PERMEase
SCIM_RS01690	COG0802	atpase or kinase
SCIM_RS01700	COG1316	TRANSCRIPTIONal
SCIM_RS01710	COG0537	adenosine 5'-monophosphoramidase activity
SCIM_RS01715	COG1131	(ABC) transporter
SCIM_RS01725	COG0510	thiamine kinase activity
SCIM_RS01730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SCIM_RS01740	COG0779	Required for maturation of 30S ribosomal subunits
SCIM_RS01745	COG0195	Participates in both transcription termination and antitermination
SCIM_RS01750	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SCIM_RS01765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SCIM_RS01770	COG1283	sodium-dependent phosphate transmembrane transporter activity
SCIM_RS01795	COG1673	EVE domain
SCIM_RS01800	COG0752	glycyl-tRNA synthetase alpha subunit
SCIM_RS01805	COG0751	glycine-tRNA ligase activity
SCIM_RS01820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SCIM_RS01845	COG0768	penicillin binding
SCIM_RS01850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCIM_RS01855	COG4166	transmembrane transport
SCIM_RS01865	COG0504	CTP synthase activity
SCIM_RS01880	COG0191	fructose-bisphosphate aldolase activity
SCIM_RS01900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SCIM_RS01910	COG1461	Dihydroxyacetone kinase
SCIM_RS01915	COG1131	(ABC) transporter
SCIM_RS01925	COG4585	Histidine kinase
SCIM_RS01930	COG2197	response regulator
SCIM_RS01945	COG1126	abc transporter atp-binding protein
SCIM_RS01950	COG0765	amino acid transport
SCIM_RS01960	COG1968	undecaprenyl-diphosphatase activity
SCIM_RS01965	COG4862	establishment of competence for transformation
SCIM_RS01970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCIM_RS01980	COG0719	Fe-S assembly protein
SCIM_RS01985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SCIM_RS01995	COG1686	Belongs to the peptidase S11 family
SCIM_RS02000	COG0513	Belongs to the DEAD box helicase family
SCIM_RS02010	COG1126	abc transporter atp-binding protein
SCIM_RS02020	COG0492	ferredoxin-NADP+ reductase activity
SCIM_RS02025	COG1113	amino acid transport
SCIM_RS02040	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SCIM_RS02045	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SCIM_RS02050	COG3579	cysteine-type endopeptidase activity
SCIM_RS02055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCIM_RS02060	COG3331	DNA recombination
SCIM_RS02065	COG4474	Belongs to the UPF0398 family
SCIM_RS02070	COG3599	regulation of cell shape
SCIM_RS02075	COG0116	Belongs to the methyltransferase superfamily
SCIM_RS02085	COG0450	alkyl hydroperoxide reductase
SCIM_RS02090	COG3634	alkyl hydroperoxide reductase activity
SCIM_RS02100	COG1418	mRNA catabolic process
SCIM_RS02105	COG0194	GDP metabolic process
SCIM_RS02110	COG1758	RNA polymerase activity
SCIM_RS02115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SCIM_RS02120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SCIM_RS02125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SCIM_RS02125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SCIM_RS02130	COG0631	protein serine/threonine phosphatase activity
SCIM_RS02135	COG0515	serine threonine protein kinase
SCIM_RS02135	COG2815	serine threonine protein kinase
SCIM_RS02145	COG4585	Histidine kinase
SCIM_RS02160	COG1185	polyribonucleotide nucleotidyltransferase activity
SCIM_RS02170	COG3557	Belongs to the UPF0374 family
SCIM_RS02175	COG2137	regulation of response to DNA damage stimulus
SCIM_RS02180	COG3231	kanamycin kinase activity
SCIM_RS02185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SCIM_RS02215	COG0519	Catalyzes the synthesis of GMP from XMP
SCIM_RS02225	COG0525	valine-tRNA ligase activity
SCIM_RS02235	COG1739	Uncharacterized protein family UPF0029
SCIM_RS02240	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SCIM_RS02245	COG1040	competence protein
SCIM_RS02255	COG0742	ribosomal rna small subunit methyltransferase
SCIM_RS02260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SCIM_RS02265	COG3480	Lon protease (S16) C-terminal proteolytic domain
SCIM_RS02270	COG4470	Protein conserved in bacteria
SCIM_RS02275	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SCIM_RS02285	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SCIM_RS02305	COG1187	pseudouridine synthase activity
SCIM_RS02310	COG1217	gtp-binding protein TYPA
SCIM_RS02320	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SCIM_RS02325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SCIM_RS02330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SCIM_RS02345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SCIM_RS02350	COG1799	cell septum assembly
SCIM_RS02365	COG3599	regulation of cell shape
SCIM_RS02370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SCIM_RS02375	COG0628	permease
SCIM_RS02385	COG1253	flavin adenine dinucleotide binding
SCIM_RS02390	COG2188	Transcriptional regulator
SCIM_RS02395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCIM_RS02395	COG1263	PTS System
SCIM_RS02400	COG0366	Alpha amylase catalytic
SCIM_RS02410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SCIM_RS02435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SCIM_RS02440	COG2244	polysaccharide biosynthetic process
SCIM_RS02455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SCIM_RS02460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SCIM_RS02465	COG0740	serine-type endopeptidase activity
SCIM_RS02470	COG4471	UPF0298 protein
SCIM_RS02480	COG0559	Belongs to the binding-protein-dependent transport system permease family
SCIM_RS02500	COG0517	IMP dehydrogenase activity
SCIM_RS02505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SCIM_RS02510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SCIM_RS02515	COG0470	DNA polymerase III
SCIM_RS02520	COG4467	Involved in initiation control of chromosome replication
SCIM_RS02530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SCIM_RS02535	COG1393	Belongs to the ArsC family
SCIM_RS02540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SCIM_RS02550	COG0708	Exodeoxyribonuclease III
SCIM_RS02585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCIM_RS02585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCIM_RS02595	COG0745	RESPONSE REGULATOR receiver
SCIM_RS02610	COG1136	(ABC) transporter
SCIM_RS02615	COG0577	efflux transmembrane transporter activity
SCIM_RS02630	COG3279	Response regulator of the LytR AlgR family
SCIM_RS02645	COG1136	(ABC) transporter
SCIM_RS02650	COG0577	efflux transmembrane transporter activity
SCIM_RS02655	COG0531	amino acid
SCIM_RS02685	COG1028	Short-chain dehydrogenase reductase Sdr
SCIM_RS02705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SCIM_RS02720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SCIM_RS02730	COG0488	(ABC) transporter
SCIM_RS02745	COG1983	PspC domain protein
SCIM_RS02750	COG0697	spore germination
SCIM_RS02750	COG1674	ftsk spoiiie
SCIM_RS02755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SCIM_RS02765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SCIM_RS02770	COG0081	regulation of translation
SCIM_RS02775	COG0528	UMP kinase activity
SCIM_RS02780	COG0233	cytoplasmic translational termination
SCIM_RS02785	COG2996	Protein conserved in bacteria
SCIM_RS02795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SCIM_RS02805	COG2274	protein secretion by the type I secretion system
SCIM_RS02810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SCIM_RS02820	COG3290	protein histidine kinase activity
SCIM_RS02890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SCIM_RS02895	COG0549	Belongs to the carbamate kinase family
SCIM_RS02900	COG1288	antiporter activity
SCIM_RS02905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCIM_RS02910	COG1438	arginine binding
SCIM_RS02915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SCIM_RS02920	COG0363	glucosamine-6-phosphate deaminase activity
SCIM_RS02935	COG2723	6-phospho-beta-galactosidase activity
SCIM_RS02945	COG4095	Psort location CytoplasmicMembrane, score
SCIM_RS02955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SCIM_RS02955	COG3711	transcriptional antiterminator
SCIM_RS02960	COG1447	Phosphotransferase system cellobiose-specific component IIA
SCIM_RS02970	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCIM_RS02985	COG4122	O-methyltransferase activity
SCIM_RS02990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SCIM_RS03000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SCIM_RS03015	COG2348	transferase activity, transferring amino-acyl groups
SCIM_RS03025	COG1078	dGTPase activity
SCIM_RS03040	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SCIM_RS03045	COG2884	Cell division ATP-binding protein ftsE
SCIM_RS03050	COG2177	Part of the ABC transporter FtsEX involved in
SCIM_RS03060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SCIM_RS03060	COG1199	ATP-dependent helicase activity
SCIM_RS03070	COG0772	Belongs to the SEDS family
SCIM_RS03075	COG0693	protein deglycase activity
SCIM_RS03085	COG0187	DNA topoisomerase II activity
SCIM_RS03090	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SCIM_RS03095	COG2706	6-phosphogluconolactonase activity
SCIM_RS03100	COG0745	RESPONSE REGULATOR receiver
SCIM_RS03105	COG5002	protein histidine kinase activity
SCIM_RS03105	COG3850	Histidine kinase
SCIM_RS03120	COG1309	transcriptional regulator
SCIM_RS03140	COG1959	2 iron, 2 sulfur cluster binding
SCIM_RS03145	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SCIM_RS03150	COG1349	DNA-binding transcription factor activity
SCIM_RS03160	COG1447	Phosphotransferase system cellobiose-specific component IIA
SCIM_RS03170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCIM_RS03175	COG1882	Formate acetyltransferase
SCIM_RS03195	COG3537	Alpha-1,2-mannosidase
SCIM_RS03205	COG0383	alpha-mannosidase activity
SCIM_RS03220	COG4209	transmembrane transport
SCIM_RS03225	COG0395	ABC-type sugar transport system, permease component
SCIM_RS03230	COG1653	transport
SCIM_RS03240	COG2972	Histidine kinase
SCIM_RS03245	COG2207	Transcriptional regulator
SCIM_RS03245	COG4753	response regulator
SCIM_RS03255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SCIM_RS03260	COG0406	alpha-ribazole phosphatase activity
SCIM_RS03265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SCIM_RS03275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SCIM_RS03280	COG0204	Acyl-transferase
SCIM_RS03300	COG1266	CAAX protease self-immunity
SCIM_RS03320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SCIM_RS03330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SCIM_RS03335	COG0322	excinuclease ABC activity
SCIM_RS03345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCIM_RS03350	COG1573	uracil-dna glycosylase
SCIM_RS03360	COG1732	Glycine betaine
SCIM_RS03365	COG1125	glycine betaine transport
SCIM_RS03380	COG0772	Belongs to the SEDS family
SCIM_RS03385	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SCIM_RS03390	COG1191	sigma factor activity
SCIM_RS03400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SCIM_RS03425	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SCIM_RS03430	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SCIM_RS03450	COG1368	sulfuric ester hydrolase activity
SCIM_RS03455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SCIM_RS03460	COG0710	3-dehydroquinate dehydratase activity
SCIM_RS03465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SCIM_RS03470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SCIM_RS03475	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SCIM_RS03480	COG0730	response to heat
SCIM_RS03490	COG0287	Prephenate dehydrogenase
SCIM_RS03495	COG3679	Belongs to the UPF0342 family
SCIM_RS03500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SCIM_RS03510	COG0077	Prephenate dehydratase
SCIM_RS03520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SCIM_RS03545	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SCIM_RS03550	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SCIM_RS03555	COG1012	belongs to the aldehyde dehydrogenase family
SCIM_RS03560	COG1882	Formate acetyltransferase
SCIM_RS03565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SCIM_RS03595	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SCIM_RS03605	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SCIM_RS03610	COG1454	alcohol dehydrogenase
SCIM_RS03610	COG1012	belongs to the aldehyde dehydrogenase family
SCIM_RS03615	COG4869	propanediol catabolic process
SCIM_RS03650	COG1216	Glycosyl transferase, family 2
SCIM_RS03650	COG1442	glycosyl transferase family 8
SCIM_RS03665	COG0463	Glycosyl transferase, family 2
SCIM_RS03670	COG1091	dTDP-4-dehydrorhamnose reductase activity
SCIM_RS03705	COG1368	sulfuric ester hydrolase activity
SCIM_RS03710	COG2384	SAM-dependent methyltransferase
SCIM_RS03715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SCIM_RS03720	COG0494	nUDIX hydrolase
SCIM_RS03725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SCIM_RS03735	COG1088	dTDP-glucose 4,6-dehydratase activity
SCIM_RS03740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SCIM_RS03745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SCIM_RS03750	COG0006	proline dipeptidase activity
SCIM_RS03755	COG1609	Transcriptional regulator
SCIM_RS03765	COG0438	transferase activity, transferring glycosyl groups
SCIM_RS03775	COG0745	RESPONSE REGULATOR receiver
SCIM_RS03780	COG5002	protein histidine kinase activity
SCIM_RS03785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SCIM_RS03790	COG2832	Protein of unknown function (DUF454)
SCIM_RS03795	COG0571	ribonuclease III activity
SCIM_RS03800	COG1196	nuclear chromosome segregation
SCIM_RS03805	COG0561	phosphatase activity
SCIM_RS03810	COG0561	phosphatase activity
SCIM_RS03815	COG0552	protein localization to endoplasmic reticulum
SCIM_RS03825	COG0574	Belongs to the PEP-utilizing enzyme family
SCIM_RS03825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SCIM_RS03830	COG0517	IMP dehydrogenase activity
SCIM_RS03835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SCIM_RS03840	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SCIM_RS03845	COG1104	cysteine desulfurase activity
SCIM_RS03850	COG0301	tRNA thio-modification
SCIM_RS03865	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SCIM_RS03875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SCIM_RS03885	COG0446	pyridine nucleotide-disulphide oxidoreductase
SCIM_RS03905	COG0583	DNA-binding transcription factor activity
SCIM_RS03910	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SCIM_RS03915	COG0564	pseudouridine synthase activity
SCIM_RS03920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SCIM_RS03930	COG2824	Alkylphosphonate utilization operon protein PhnA
SCIM_RS03950	COG0038	chloride channel
SCIM_RS03955	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SCIM_RS03960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SCIM_RS03970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SCIM_RS03975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SCIM_RS03980	COG1705	Flagellar rod assembly protein muramidase FlgJ
SCIM_RS03980	COG1388	LysM domain
SCIM_RS03995	COG1132	(ABC) transporter
SCIM_RS04000	COG0488	(ABC) transporter
SCIM_RS04015	COG0556	nucleotide-excision repair
SCIM_RS04035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SCIM_RS04045	COG1051	belongs to the nudix hydrolase family
SCIM_RS04050	COG0647	UMP catabolic process
SCIM_RS04070	COG1660	Displays ATPase and GTPase activities
SCIM_RS04075	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SCIM_RS04080	COG1481	regulation of sporulation
SCIM_RS04235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SCIM_RS04235	COG0551	DNA topoisomerase type I activity
SCIM_RS04240	COG0542	response to heat
SCIM_RS04345	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SCIM_RS04355	COG0540	Belongs to the ATCase OTCase family
SCIM_RS04360	COG0505	Belongs to the CarA family
SCIM_RS04365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SCIM_RS04370	COG1940	carbohydrate kinase activity
SCIM_RS04395	COG0745	RESPONSE REGULATOR receiver
SCIM_RS04400	COG5002	protein histidine kinase activity
SCIM_RS04420	COG1072	(Pantothenic acid kinase))
SCIM_RS04425	COG2813	Specifically methylates the guanine in position
SCIM_RS04435	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SCIM_RS04440	COG0295	cytidine deaminase activity
SCIM_RS04445	COG1744	ABC transporter substrate-binding protein PnrA-like
SCIM_RS04450	COG3845	ABC transporter
SCIM_RS04455	COG4603	Belongs to the binding-protein-dependent transport system permease family
SCIM_RS04460	COG1079	Belongs to the binding-protein-dependent transport system permease family
SCIM_RS04465	COG1272	protein, Hemolysin III
SCIM_RS04475	COG3022	response to hydroperoxide
SCIM_RS04485	COG1846	Transcriptional regulator
SCIM_RS04495	COG0436	Aminotransferase
SCIM_RS04505	COG0017	Asparaginyl-tRNA synthetase
SCIM_RS04510	COG2814	Major facilitator Superfamily
SCIM_RS04565	COG1309	transcriptional regulator
SCIM_RS04570	COG2131	deaminase
SCIM_RS04580	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SCIM_RS04585	COG0187	DNA topoisomerase II activity
SCIM_RS04595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SCIM_RS04600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SCIM_RS04620	COG0539	negative regulation of cytoplasmic translation
SCIM_RS04635	COG0039	L-malate dehydrogenase activity
SCIM_RS04640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SCIM_RS04645	COG3764	Sortase (surface protein transpeptidase)
SCIM_RS04650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SCIM_RS04655	COG1970	mechanosensitive ion channel activity
SCIM_RS04660	COG0358	DNA primase activity
SCIM_RS04665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SCIM_RS04670	COG2151	metal-sulfur cluster biosynthetic enzyme
SCIM_RS04680	COG0785	Cytochrome C biogenesis protein
SCIM_RS04685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCIM_RS04690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCIM_RS04690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCIM_RS04695	COG2207	Transcriptional regulator
SCIM_RS04695	COG4753	response regulator
SCIM_RS04700	COG2972	Histidine kinase
SCIM_RS04715	COG4555	ABC transporter
SCIM_RS04720	COG3976	FMN-binding domain protein
SCIM_RS04720	COG1053	succinate dehydrogenase
SCIM_RS04720	COG0431	NADPH-dependent FMN reductase
SCIM_RS04760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SCIM_RS04765	COG2233	PERMEase
SCIM_RS04770	COG0534	Mate efflux family protein
SCIM_RS04775	COG1942	4-Oxalocrotonate Tautomerase
SCIM_RS04780	COG1435	thymidine kinase activity
SCIM_RS04785	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SCIM_RS04790	COG2890	protein-(glutamine-N5) methyltransferase activity
SCIM_RS04795	COG0009	L-threonylcarbamoyladenylate synthase
SCIM_RS04800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SCIM_RS04810	COG0741	lytic transglycosylase activity
SCIM_RS04825	COG2188	Transcriptional regulator
SCIM_RS04835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SCIM_RS04840	COG4974	Belongs to the 'phage' integrase family
SCIM_RS04865	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SCIM_RS04870	COG0135	phosphoribosylanthranilate isomerase activity
SCIM_RS04875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SCIM_RS04880	COG0758	DNA mediated transformation
SCIM_RS04885	COG0110	maltose O-acetyltransferase activity
SCIM_RS04890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SCIM_RS04900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SCIM_RS04915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SCIM_RS04920	COG1132	(ABC) transporter
SCIM_RS04925	COG1132	(ABC) transporter
SCIM_RS04930	COG2315	Protein conserved in bacteria
SCIM_RS04935	COG3142	Participates in the control of copper homeostasis
SCIM_RS04950	COG1827	regulation of RNA biosynthetic process
SCIM_RS04955	COG1837	Belongs to the UPF0109 family
SCIM_RS04960	COG0228	four-way junction DNA binding
SCIM_RS04965	COG1523	belongs to the glycosyl hydrolase 13 family
SCIM_RS04970	COG1597	lipid kinase activity
SCIM_RS04975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SCIM_RS04980	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SCIM_RS04990	COG4708	membrane
SCIM_RS04995	COG2246	polysaccharide biosynthetic process
SCIM_RS05005	COG1846	Transcriptional regulator
SCIM_RS05020	COG4109	DRTGG domain
SCIM_RS05025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SCIM_RS05030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SCIM_RS05035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SCIM_RS05040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SCIM_RS05045	COG1051	belongs to the nudix hydrolase family
SCIM_RS05050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SCIM_RS05065	COG0658	competence protein
SCIM_RS05065	COG2333	competence protein COMEC
SCIM_RS05075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SCIM_RS05080	COG0557	exoribonuclease II activity
SCIM_RS05090	COG2814	Major facilitator Superfamily
SCIM_RS05095	COG0237	dephospho-CoA kinase activity
SCIM_RS05100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SCIM_RS05105	COG0456	acetyltransferase
SCIM_RS05135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SCIM_RS05145	COG1132	(ABC) transporter
SCIM_RS05150	COG1132	(ABC) transporter
SCIM_RS05165	COG0686	Belongs to the AlaDH PNT family
SCIM_RS05185	COG1702	phosphate starvation-inducible protein PhoH
SCIM_RS05190	COG4479	Belongs to the UPF0346 family
SCIM_RS05195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SCIM_RS05205	COG0284	orotidine-5'-phosphate decarboxylase activity
SCIM_RS05210	COG0167	dihydroorotate dehydrogenase activity
SCIM_RS05215	COG0543	2 iron, 2 sulfur cluster binding
SCIM_RS05225	COG2814	Major facilitator Superfamily
SCIM_RS05245	COG0083	homoserine kinase activity
SCIM_RS05255	COG0726	polysaccharide deacetylase
SCIM_RS05265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SCIM_RS05275	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SCIM_RS05280	COG1609	Transcriptional regulator
SCIM_RS05285	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SCIM_RS05285	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SCIM_RS05295	COG2860	membrane
SCIM_RS05305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCIM_RS05310	COG0626	cystathionine gamma-synthase activity
SCIM_RS05315	COG0251	oxidation-reduction process
SCIM_RS05325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SCIM_RS05335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SCIM_RS05340	COG1956	GAF domain-containing protein
SCIM_RS05360	COG0803	Belongs to the bacterial solute-binding protein 9 family
SCIM_RS05360	COG3443	Belongs to the bacterial solute-binding protein 9 family
SCIM_RS05365	COG0336	Belongs to the RNA methyltransferase TrmD family
SCIM_RS05370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SCIM_RS05380	COG0222	ribosome binding
SCIM_RS05385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SCIM_RS05390	COG2207	Transcriptional regulator
SCIM_RS05390	COG3708	Transcriptional regulator
SCIM_RS05410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCIM_RS05415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SCIM_RS05425	COG1177	transmembrane transport
SCIM_RS05430	COG1176	ABC-type spermidine putrescine transport system, permease component I
SCIM_RS05435	COG3842	ATPase activity
SCIM_RS05440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SCIM_RS05445	COG0481	GTPase activity
SCIM_RS05450	COG0561	phosphatase activity
SCIM_RS05460	COG2195	Cleaves the N-terminal amino acid of tripeptides
SCIM_RS05465	COG0572	uridine kinase
SCIM_RS05470	COG0673	inositol 2-dehydrogenase activity
SCIM_RS05480	COG0726	polysaccharide deacetylase
SCIM_RS05495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SCIM_RS05505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SCIM_RS05530	COG0560	Phosphoserine phosphatase
SCIM_RS05535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SCIM_RS05545	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SCIM_RS05550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SCIM_RS05555	COG3442	glutamine amidotransferase
SCIM_RS05565	COG0488	(ABC) transporter
SCIM_RS05590	COG0826	peptidase U32
SCIM_RS05615	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SCIM_RS05620	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SCIM_RS05625	COG1051	belongs to the nudix hydrolase family
SCIM_RS05635	COG3091	SprT-like family
SCIM_RS05640	COG2183	response to ionizing radiation
SCIM_RS05645	COG0701	Predicted permease
SCIM_RS05650	COG3689	TIGRFAM TIGR03943 family protein
SCIM_RS05655	COG0477	Major facilitator Superfamily
SCIM_RS05660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SCIM_RS05680	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SCIM_RS05690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SCIM_RS05695	COG4684	Psort location CytoplasmicMembrane, score
SCIM_RS05700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SCIM_RS05710	COG1194	a g-specific adenine glycosylase
SCIM_RS05715	COG0280	phosphate acetyltransferase
SCIM_RS05720	COG0564	pseudouridine synthase activity
SCIM_RS05730	COG2357	RelA SpoT domain protein
SCIM_RS05740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SCIM_RS05745	COG1104	cysteine desulfurase activity
SCIM_RS05765	COG2003	Belongs to the UPF0758 family
SCIM_RS05770	COG0704	Plays a role in the regulation of phosphate uptake
SCIM_RS05775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SCIM_RS05780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SCIM_RS05785	COG0581	inorganic phosphate transmembrane transporter activity
SCIM_RS05790	COG0573	inorganic phosphate transmembrane transporter activity
SCIM_RS05800	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SCIM_RS05800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SCIM_RS05805	COG0483	inositol monophosphate 1-phosphatase activity
SCIM_RS05810	COG4476	Belongs to the UPF0223 family
SCIM_RS05815	COG1393	Belongs to the ArsC family
SCIM_RS05820	COG0196	riboflavin kinase activity
SCIM_RS05825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SCIM_RS05855	COG1132	(ABC) transporter
SCIM_RS05860	COG2375	cellular response to nickel ion
SCIM_RS05860	COG1132	(ABC) transporter
SCIM_RS05870	COG0494	nUDIX hydrolase
SCIM_RS05875	COG0210	DNA helicase
SCIM_RS05880	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SCIM_RS05895	COG0469	pyruvate kinase activity
SCIM_RS05900	COG0205	6-phosphofructokinase activity
SCIM_RS05915	COG1131	(ABC) transporter
SCIM_RS05920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SCIM_RS05920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SCIM_RS05940	COG0300	oxidoreductase activity
SCIM_RS05960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SCIM_RS05965	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SCIM_RS05970	COG0577	efflux transmembrane transporter activity
SCIM_RS05970	COG1136	(ABC) transporter
SCIM_RS05975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SCIM_RS05980	COG1268	BioY protein
SCIM_RS05985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCIM_RS05985	COG0072	phenylalanine-tRNA ligase activity
SCIM_RS06000	COG0488	(ABC) transporter
SCIM_RS06005	COG0617	tRNA 3'-terminal CCA addition
SCIM_RS06010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SCIM_RS06015	COG1307	EDD domain protein, DegV family
SCIM_RS06025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SCIM_RS06025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SCIM_RS06025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SCIM_RS06030	COG1105	Belongs to the carbohydrate kinase PfkB family
SCIM_RS06035	COG1349	DNA-binding transcription factor activity
SCIM_RS06045	COG0492	ferredoxin-NADP+ reductase activity
SCIM_RS06050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SCIM_RS06065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SCIM_RS06070	COG1346	cytolysis
SCIM_RS06090	COG1132	(ABC) transporter
SCIM_RS06110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SCIM_RS06140	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SCIM_RS06145	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SCIM_RS06150	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SCIM_RS06155	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SCIM_RS06160	COG0356	it plays a direct role in the translocation of protons across the membrane
SCIM_RS06170	COG0058	SHG alpha-glucan phosphorylase activity
SCIM_RS06175	COG0297	glycogen (starch) synthase activity
SCIM_RS06190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SCIM_RS06195	COG1074	ATP-dependent DNA helicase activity
SCIM_RS06200	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SCIM_RS06205	COG1668	transmembrane transport
SCIM_RS06210	COG4152	abc transporter atp-binding protein
SCIM_RS06230	COG4443	Transcriptional Coactivator p15 (PC4)
SCIM_RS06255	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SCIM_RS06260	COG3527	Alpha-acetolactate decarboxylase
SCIM_RS06265	COG0028	Belongs to the TPP enzyme family
SCIM_RS06275	COG0628	permease
SCIM_RS06285	COG0716	FMN binding
SCIM_RS06290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SCIM_RS06295	COG0254	rRNA binding
SCIM_RS06300	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SCIM_RS06305	COG2827	Endonuclease containing a URI domain
SCIM_RS06310	COG1755	Isoprenylcysteine carboxyl methyltransferase
SCIM_RS06315	COG2723	6-phospho-beta-galactosidase activity
SCIM_RS06320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCIM_RS06320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCIM_RS06325	COG1447	Phosphotransferase system cellobiose-specific component IIA
SCIM_RS06330	COG3711	transcriptional antiterminator
SCIM_RS06335	COG3583	domain protein
SCIM_RS06335	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SCIM_RS06335	COG3064	Membrane
SCIM_RS06340	COG1105	Belongs to the carbohydrate kinase PfkB family
SCIM_RS06345	COG3775	system Galactitol-specific IIC component
SCIM_RS06365	COG0698	ribose 5-phosphate isomerase
SCIM_RS06380	COG0513	Belongs to the DEAD box helicase family
SCIM_RS06395	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SCIM_RS06405	COG3620	sequence-specific DNA binding
SCIM_RS06425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SCIM_RS06430	COG1181	Belongs to the D-alanine--D-alanine ligase family
SCIM_RS06435	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SCIM_RS06440	COG0768	penicillin binding
SCIM_RS06445	COG0588	phosphoglycerate mutase activity
SCIM_RS06450	COG0735	belongs to the Fur family
SCIM_RS06460	COG1307	EDD domain protein, DegV family
SCIM_RS06465	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SCIM_RS06470	COG4605	iron ion homeostasis
SCIM_RS06475	COG4604	ABC transporter, ATP-binding protein
SCIM_RS06485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SCIM_RS06490	COG0497	DNA recombination
SCIM_RS06495	COG1438	arginine binding
SCIM_RS06500	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SCIM_RS06510	COG1722	exodeoxyribonuclease VII activity
SCIM_RS06515	COG1570	exodeoxyribonuclease VII activity
SCIM_RS06530	COG1621	beta-fructofuranosidase activity
SCIM_RS06535	COG0395	ABC-type sugar transport system, permease component
SCIM_RS06540	COG1175	transmembrane transport
SCIM_RS06555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SCIM_RS06560	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SCIM_RS06565	COG0577	efflux transmembrane transporter activity
SCIM_RS06570	COG1136	(ABC) transporter
SCIM_RS06590	COG4703	Protein of unknown function (DUF1797)
SCIM_RS06595	COG0542	response to heat
SCIM_RS06605	COG2378	regulation of single-species biofilm formation
SCIM_RS06610	COG0494	nUDIX hydrolase
SCIM_RS06620	COG0025	NhaP-type Na H and K H
SCIM_RS06630	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SCIM_RS06635	COG1242	4 iron, 4 sulfur cluster binding
SCIM_RS06645	COG0671	phosphoesterase, PA-phosphatase related
SCIM_RS06650	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SCIM_RS06660	COG0569	domain protein
SCIM_RS06665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SCIM_RS06675	COG1187	pseudouridine synthase activity
SCIM_RS06685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SCIM_RS06690	COG4974	Belongs to the 'phage' integrase family
SCIM_RS06695	COG0517	IMP dehydrogenase activity
SCIM_RS06705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SCIM_RS06710	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SCIM_RS06735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SCIM_RS06740	COG1254	Belongs to the acylphosphatase family
SCIM_RS06760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SCIM_RS06775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SCIM_RS06785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SCIM_RS06790	COG1160	GTP binding
SCIM_RS06800	COG1484	DNA-dependent DNA replication
SCIM_RS06810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SCIM_RS06825	COG1263	PTS System
SCIM_RS06825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCIM_RS06825	COG2190	(PTS) system
SCIM_RS06830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCIM_RS06830	COG1263	PTS System
SCIM_RS06830	COG2190	(PTS) system
SCIM_RS06835	COG0745	RESPONSE REGULATOR receiver
SCIM_RS06840	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SCIM_RS06855	COG0501	Belongs to the peptidase M48B family
SCIM_RS06860	COG1704	LemA family
SCIM_RS06865	COG0357	Ribosomal RNA small subunit methyltransferase G
SCIM_RS06875	COG1442	glycosyl transferase family 8
SCIM_RS06880	COG4221	oxidoreductase activity
SCIM_RS06890	COG1122	ATPase activity
SCIM_RS06920	COG4720	Psort location CytoplasmicMembrane, score
SCIM_RS07010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SCIM_RS07015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCIM_RS07020	COG1464	Belongs to the NlpA lipoprotein family
SCIM_RS07025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SCIM_RS07040	COG1323	Belongs to the UPF0348 family
SCIM_RS07050	COG3177	Filamentation induced by cAMP protein fic
SCIM_RS07070	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SCIM_RS07075	COG2226	methyltransferase
SCIM_RS07080	COG0799	negative regulation of ribosome biogenesis
SCIM_RS07090	COG1713	HD superfamily hydrolase involved in NAD metabolism
SCIM_RS07095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SCIM_RS07100	COG1534	Rna-binding protein
SCIM_RS07105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SCIM_RS07110	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SCIM_RS07125	COG1063	alcohol dehydrogenase
SCIM_RS07130	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SCIM_RS07135	COG0154	amidase activity
SCIM_RS07140	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SCIM_RS07145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SCIM_RS07150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SCIM_RS07155	COG1335	isochorismatase
SCIM_RS07160	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SCIM_RS07165	COG0436	Aminotransferase
SCIM_RS07170	COG0589	response to stress
SCIM_RS07175	COG0561	phosphatase activity
SCIM_RS07180	COG0252	asparaginase activity
SCIM_RS07185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SCIM_RS07190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SCIM_RS07195	COG0736	holo-[acyl-carrier-protein] synthase activity
SCIM_RS07200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SCIM_RS07255	COG1482	cell wall glycoprotein biosynthetic process
SCIM_RS07260	COG2188	Transcriptional regulator
SCIM_RS07265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SCIM_RS07270	COG2723	6-phospho-beta-galactosidase activity
SCIM_RS07280	COG1132	(ABC) transporter
SCIM_RS07295	COG1902	pentaerythritol trinitrate reductase activity
SCIM_RS07300	COG0242	peptide deformylase activity
SCIM_RS07305	COG1940	carbohydrate kinase activity
SCIM_RS07310	COG2190	(PTS) system
SCIM_RS07310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCIM_RS07310	COG1263	PTS System
SCIM_RS07315	COG1621	beta-fructofuranosidase activity
SCIM_RS07320	COG1609	Transcriptional regulator
SCIM_RS07325	COG0561	phosphatase activity
SCIM_RS07330	COG4608	Belongs to the ABC transporter superfamily
SCIM_RS07335	COG0444	Belongs to the ABC transporter superfamily
SCIM_RS07340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SCIM_RS07345	COG0601	transmembrane transport
SCIM_RS07350	COG4166	transmembrane transport
SCIM_RS07355	COG4166	transmembrane transport
SCIM_RS07365	COG0504	CTP synthase activity
SCIM_RS07370	COG3343	RNA polymerase activity
SCIM_RS07375	COG0544	peptidyl-prolyl cis-trans isomerase activity
SCIM_RS07380	COG4475	Protein of unknown function (DUF436)
SCIM_RS07385	COG4720	Psort location CytoplasmicMembrane, score
SCIM_RS07390	COG0351	phosphomethylpyrimidine kinase
SCIM_RS07395	COG0101	tRNA pseudouridine synthase activity
SCIM_RS07405	COG0484	heat shock protein binding
SCIM_RS07410	COG0443	Heat shock 70 kDa protein
SCIM_RS07415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SCIM_RS07420	COG1420	regulation of RNA biosynthetic process
SCIM_RS07460	COG2848	UPF0210 protein
SCIM_RS07465	COG3830	Belongs to the UPF0237 family
SCIM_RS07470	COG1609	Transcriptional regulator
SCIM_RS07485	COG3716	PTS system mannose fructose sorbose family IID component
SCIM_RS07490	COG3715	PTS system
SCIM_RS07495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SCIM_RS07500	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SCIM_RS07510	COG1028	Short-chain dehydrogenase reductase Sdr
SCIM_RS07535	COG5492	domain, Protein
SCIM_RS07540	COG0386	Belongs to the glutathione peroxidase family
SCIM_RS07550	COG0281	malic enzyme
SCIM_RS07560	COG0583	DNA-binding transcription factor activity
SCIM_RS07580	COG2217	Heavy metal translocating P-type atpase
SCIM_RS07590	COG3328	transposase activity
SCIM_RS07595	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SCIM_RS07600	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SCIM_RS07615	COG3842	ATPase activity
SCIM_RS07625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SCIM_RS07630	COG0215	cysteine-tRNA ligase activity
SCIM_RS07640	COG1045	serine acetyltransferase
SCIM_RS07645	COG1185	polyribonucleotide nucleotidyltransferase activity
SCIM_RS07650	COG1164	Oligoendopeptidase f
SCIM_RS07665	COG1187	pseudouridine synthase activity
SCIM_RS07730	COG2309	aminopeptidase activity
SCIM_RS07740	COG2176	DNA-directed DNA polymerase activity
SCIM_RS07745	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SCIM_RS07750	COG1523	belongs to the glycosyl hydrolase 13 family
SCIM_RS07760	COG3590	peptidase
SCIM_RS07790	COG1309	transcriptional regulator
SCIM_RS07795	COG2226	methyltransferase
SCIM_RS07800	COG2746	aminoglycoside 3-N-acetyltransferase activity
SCIM_RS07850	COG1940	carbohydrate kinase activity
SCIM_RS07850	COG1846	Transcriptional regulator
SCIM_RS07860	COG2249	NAD(P)H dehydrogenase (quinone) activity
SCIM_RS07865	COG0346	lactoylglutathione lyase activity
SCIM_RS07910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SCIM_RS07935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SCIM_RS07955	COG0604	alcohol dehydrogenase
SCIM_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
SCIM_RS07955	COG3321	synthase
SCIM_RS07960	COG0596	Alpha beta hydrolase
SCIM_RS07975	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SCIM_RS07990	COG1136	(ABC) transporter
SCIM_RS08010	COG1959	2 iron, 2 sulfur cluster binding
SCIM_RS08030	COG0459	protein refolding
SCIM_RS08045	COG3716	PTS system mannose fructose sorbose family IID component
SCIM_RS08050	COG3715	PTS system
SCIM_RS08070	COG2197	response regulator
SCIM_RS08075	COG4585	Histidine kinase
SCIM_RS08090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCIM_RS08095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCIM_RS08105	COG1363	Peptidase, m42
SCIM_RS08115	COG0285	dihydrofolate synthase activity
SCIM_RS08125	COG0442	prolyl-tRNA aminoacylation
SCIM_RS08130	COG0750	zinc metalloprotease
SCIM_RS08135	COG4589	Belongs to the CDS family
SCIM_RS08140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SCIM_RS08150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SCIM_RS08170	COG3623	hexulose-6-phosphate isomerase
SCIM_RS08180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SCIM_RS08190	COG3037	sugar-specific permease SgaT UlaA
SCIM_RS08205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SCIM_RS08210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SCIM_RS08235	COG4537	Required for transformation and DNA binding
SCIM_RS08240	COG1459	type II secretion system
SCIM_RS08245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SCIM_RS08255	COG0174	glutamine synthetase
SCIM_RS08260	COG0789	Transcriptional regulator
SCIM_RS08270	COG3942	CHAP domain
SCIM_RS08280	COG0126	phosphoglycerate kinase activity
SCIM_RS08285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SCIM_RS08290	COG0085	RNA polymerase activity
SCIM_RS08295	COG1136	(ABC) transporter
SCIM_RS08295	COG0577	efflux transmembrane transporter activity
SCIM_RS08310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCIM_RS08310	COG4499	WXG100 protein secretion system (Wss), protein YukC
SCIM_RS08320	COG0500	methyltransferase
SCIM_RS08330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SCIM_RS08335	COG1473	amidohydrolase
SCIM_RS08340	COG2171	N-acyltransferase activity
SCIM_RS08345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SCIM_RS08360	COG0756	dUTP diphosphatase activity
SCIM_RS08370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SCIM_RS08375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SCIM_RS08530	COG0203	ribosomal protein L17
SCIM_RS08535	COG0202	RNA polymerase activity
SCIM_RS08540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SCIM_RS08545	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SCIM_RS08550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SCIM_RS08555	COG0563	adenylate kinase activity
SCIM_RS08560	COG0201	protein transport
SCIM_RS08565	COG0200	Binds to the 23S rRNA
SCIM_RS08570	COG1841	ribosomal large subunit assembly
SCIM_RS08575	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SCIM_RS08585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SCIM_RS08590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SCIM_RS08595	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SCIM_RS08600	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SCIM_RS08605	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SCIM_RS08615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SCIM_RS08620	COG0255	Belongs to the universal ribosomal protein uL29 family
SCIM_RS08625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SCIM_RS08630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SCIM_RS08635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SCIM_RS08645	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SCIM_RS08650	COG0089	rRNA binding
SCIM_RS08655	COG0088	Forms part of the polypeptide exit tunnel
SCIM_RS08660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SCIM_RS08665	COG0051	transcription antitermination factor activity, RNA binding
SCIM_RS08675	COG0343	queuine tRNA-ribosyltransferase activity
SCIM_RS08690	COG1832	CoA-binding protein
SCIM_RS08695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SCIM_RS08695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SCIM_RS08725	COG5002	protein histidine kinase activity
SCIM_RS08755	COG1216	Glycosyl transferase, family 2
SCIM_RS08760	COG0438	transferase activity, transferring glycosyl groups
SCIM_RS08770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SCIM_RS08785	COG3944	biosynthesis protein
SCIM_RS08790	COG4464	protein tyrosine phosphatase activity
SCIM_RS08800	COG0602	queuosine metabolic process
SCIM_RS08825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SCIM_RS08845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SCIM_RS08850	COG4472	Bacterial protein of unknown function (DUF965)
SCIM_RS08865	COG1393	Belongs to the ArsC family
SCIM_RS08870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SCIM_RS08875	COG1058	Belongs to the CinA family
SCIM_RS08875	COG1546	Belongs to the CinA family
SCIM_RS08885	COG1266	CAAX protease self-immunity
SCIM_RS08890	COG2818	Glycosylase
SCIM_RS08895	COG0632	four-way junction helicase activity
SCIM_RS08900	COG1395	domain, Protein
SCIM_RS08910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SCIM_RS08915	COG0582	viral genome integration into host DNA
SCIM_RS09025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SCIM_RS09030	COG1438	arginine binding
SCIM_RS09035	COG0018	arginyl-trna synthetase
SCIM_RS09040	COG1780	Probably involved in ribonucleotide reductase function
SCIM_RS09050	COG0058	SHG alpha-glucan phosphorylase activity
SCIM_RS09055	COG1640	4-alpha-glucanotransferase
SCIM_RS09060	COG2182	Extracellular solute-binding protein
SCIM_RS09065	COG1175	transmembrane transport
SCIM_RS09070	COG3833	ABC-type maltose transport systems, permease component
SCIM_RS09075	COG5521	maltodextrose utilization protein MalA
SCIM_RS09080	COG1609	Transcriptional regulator
SCIM_RS09085	COG1523	belongs to the glycosyl hydrolase 13 family
SCIM_RS09090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SCIM_RS09105	COG0124	histidyl-tRNA synthetase
SCIM_RS09110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SCIM_RS09115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SCIM_RS09170	COG4974	Belongs to the 'phage' integrase family
SCIM_RS09185	COG1396	sequence-specific DNA binding
SCIM_RS09190	COG2217	Heavy metal translocating P-type atpase
SCIM_RS09195	COG2807	transmembrane transport
SCIM_RS09200	COG2094	Belongs to the DNA glycosylase MPG family
SCIM_RS09210	COG0561	phosphatase activity
SCIM_RS09220	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SCIM_RS09225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCIM_RS09230	COG1696	Membrane protein involved in D-alanine export
SCIM_RS09300	COG0561	phosphatase activity
SCIM_RS09315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SCIM_RS09320	COG1011	Hydrolase
SCIM_RS09330	COG0305	Participates in initiation and elongation during chromosome replication
SCIM_RS09345	COG0445	tRNA wobble uridine modification
SCIM_RS09350	COG0482	sulfurtransferase activity
SCIM_RS09360	COG1760	l-serine dehydratase
SCIM_RS09365	COG1760	l-serine dehydratase
SCIM_RS09375	COG0741	lytic transglycosylase activity
SCIM_RS09380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SCIM_RS09385	COG1122	ATPase activity
SCIM_RS09390	COG1122	ATPase activity
SCIM_RS09395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SCIM_RS09405	COG0612	Peptidase, M16
SCIM_RS09410	COG0612	Peptidase, M16
SCIM_RS09420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SCIM_RS09425	COG0517	IMP dehydrogenase activity
SCIM_RS09425	COG0516	GMP reductase activity
SCIM_RS09430	COG0180	Tryptophanyl-tRNA synthetase
SCIM_RS09435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SCIM_RS09440	COG0149	triose-phosphate isomerase activity
SCIM_RS09450	COG0488	(ABC) transporter
SCIM_RS09475	COG4191	Histidine kinase
SCIM_RS09490	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SCIM_RS09495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCIM_RS09500	COG1475	DNA binding