locus-tag	class	description
KE3_RS00010	COG0592	DNA-directed DNA polymerase activity
KE3_RS00025	COG0012	GTP binding
KE3_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KE3_RS00040	COG3620	sequence-specific DNA binding
KE3_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KE3_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KE3_RS00105	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KE3_RS00115	COG1121	(ABC) transporter
KE3_RS00120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KE3_RS00195	COG2826	transposase and inactivated derivatives, IS30 family
KE3_RS00235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KE3_RS00240	COG1459	type II secretion system
KE3_RS00245	COG4537	Required for transformation and DNA binding
KE3_RS00300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KE3_RS00305	COG1363	Peptidase, m42
KE3_RS00315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KE3_RS00320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KE3_RS00350	COG4120	Belongs to the binding-protein-dependent transport system permease family
KE3_RS00355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KE3_RS00380	COG0564	pseudouridine synthase activity
KE3_RS00395	COG2223	nitrite transmembrane transporter activity
KE3_RS00405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KE3_RS00410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KE3_RS00430	COG4667	esterase of the alpha-beta hydrolase superfamily
KE3_RS00440	COG2017	converts alpha-aldose to the beta-anomer
KE3_RS00450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KE3_RS00460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KE3_RS00485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KE3_RS00495	COG2190	(PTS) system
KE3_RS00495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KE3_RS00495	COG1263	PTS System
KE3_RS00510	COG1363	Peptidase, m42
KE3_RS00515	COG1609	Transcriptional regulator
KE3_RS00520	COG1653	transport
KE3_RS00535	COG3842	ATPase activity
KE3_RS00550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KE3_RS00555	COG1447	Phosphotransferase system cellobiose-specific component IIA
KE3_RS00560	COG2723	6-phospho-beta-galactosidase activity
KE3_RS00565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KE3_RS00570	COG2188	Transcriptional regulator
KE3_RS00575	COG1482	cell wall glycoprotein biosynthetic process
KE3_RS00585	COG2188	Transcriptional regulator
KE3_RS00590	COG1940	carbohydrate kinase activity
KE3_RS00615	COG3842	ATPase activity
KE3_RS00625	COG0698	ribose 5-phosphate isomerase
KE3_RS00655	COG3775	system Galactitol-specific IIC component
KE3_RS00665	COG3711	transcriptional antiterminator
KE3_RS00670	COG2723	6-phospho-beta-galactosidase activity
KE3_RS00675	COG3711	transcriptional antiterminator
KE3_RS00720	COG2207	Transcriptional regulator
KE3_RS00725	COG3345	alpha-galactosidase
KE3_RS00730	COG1653	transport
KE3_RS00735	COG1175	transmembrane transport
KE3_RS00740	COG0395	ABC-type sugar transport system, permease component
KE3_RS00745	COG0366	Alpha amylase catalytic
KE3_RS00750	COG0366	Alpha amylase catalytic
KE3_RS00755	COG1609	Transcriptional regulator
KE3_RS00760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KE3_RS00765	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KE3_RS00770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KE3_RS00780	COG1862	Preprotein translocase
KE3_RS00785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KE3_RS00790	COG4589	Belongs to the CDS family
KE3_RS00810	COG1846	Transcriptional regulator
KE3_RS00815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KE3_RS00840	COG1454	alcohol dehydrogenase
KE3_RS00840	COG1012	belongs to the aldehyde dehydrogenase family
KE3_RS00850	COG1185	polyribonucleotide nucleotidyltransferase activity
KE3_RS00860	COG1045	serine acetyltransferase
KE3_RS00870	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KE3_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KE3_RS00905	COG0582	viral genome integration into host DNA
KE3_RS00965	COG1121	(ABC) transporter
KE3_RS01005	COG1674	ftsk spoiiie
KE3_RS01030	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KE3_RS01115	COG3830	Belongs to the UPF0237 family
KE3_RS01130	COG1876	peptidase activity
KE3_RS01135	COG1705	Flagellar rod assembly protein muramidase FlgJ
KE3_RS01150	COG0443	Heat shock 70 kDa protein
KE3_RS01165	COG0351	phosphomethylpyrimidine kinase
KE3_RS01180	COG0668	transmembrane transport
KE3_RS01195	COG0504	CTP synthase activity
KE3_RS01225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KE3_RS01235	COG1461	Dihydroxyacetone kinase
KE3_RS01245	COG0129	dihydroxy-acid dehydratase activity
KE3_RS01250	COG0028	Belongs to the TPP enzyme family
KE3_RS01255	COG0440	acetolactate synthase activity
KE3_RS01265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KE3_RS01275	COG1126	abc transporter atp-binding protein
KE3_RS01280	COG0765	amino acid transport
KE3_RS01300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KE3_RS01310	COG0719	Fe-S assembly protein
KE3_RS01315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KE3_RS01325	COG0719	Fe-S assembly protein
KE3_RS01330	COG1686	Belongs to the peptidase S11 family
KE3_RS01335	COG4166	transmembrane transport
KE3_RS01340	COG0601	transmembrane transport
KE3_RS01345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KE3_RS01350	COG0444	Belongs to the ABC transporter superfamily
KE3_RS01355	COG4608	Belongs to the ABC transporter superfamily
KE3_RS01555	COG1792	Involved in formation and maintenance of cell shape
KE3_RS01565	COG3942	CHAP domain
KE3_RS01575	COG0436	Aminotransferase
KE3_RS01585	COG0416	fatty acid biosynthetic process
KE3_RS01590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KE3_RS01595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KE3_RS01600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KE3_RS01610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KE3_RS01615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KE3_RS01625	COG0151	Belongs to the GarS family
KE3_RS01630	COG1683	Conserved Protein
KE3_RS01635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KE3_RS01645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KE3_RS01665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KE3_RS01675	COG2755	lipolytic protein G-D-S-L family
KE3_RS01675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KE3_RS01680	COG2801	Transposase and inactivated derivatives
KE3_RS01695	COG0534	Mate efflux family protein
KE3_RS01700	COG0051	transcription antitermination factor activity, RNA binding
KE3_RS01710	COG0088	Forms part of the polypeptide exit tunnel
KE3_RS01715	COG0089	rRNA binding
KE3_RS01745	COG0255	Belongs to the universal ribosomal protein uL29 family
KE3_RS01760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KE3_RS01770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KE3_RS01790	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KE3_RS01795	COG1841	ribosomal large subunit assembly
KE3_RS01805	COG0201	protein transport
KE3_RS01830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KE3_RS01835	COG0202	RNA polymerase activity
KE3_RS01840	COG0203	ribosomal protein L17
KE3_RS01880	COG0527	aspartate kinase activity
KE3_RS01885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KE3_RS01890	COG1024	Enoyl-CoA hydratase
KE3_RS01900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KE3_RS01910	COG2070	2-Nitropropane dioxygenase
KE3_RS01915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KE3_RS01920	COG1028	Short-chain dehydrogenase reductase Sdr
KE3_RS01925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KE3_RS01940	COG0439	Biotin carboxylase
KE3_RS01955	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KE3_RS01965	COG3716	PTS system mannose fructose sorbose family IID component
KE3_RS01970	COG3715	PTS system
KE3_RS01980	COG0561	phosphatase activity
KE3_RS01995	COG2252	PERMEase
KE3_RS02000	COG0802	atpase or kinase
KE3_RS02010	COG1316	TRANSCRIPTIONal
KE3_RS02020	COG0537	adenosine 5'-monophosphoramidase activity
KE3_RS02025	COG1131	(ABC) transporter
KE3_RS02030	COG4473	ABC transporter
KE3_RS02040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KE3_RS02050	COG3447	MASE1 domain protein
KE3_RS02050	COG5001	Diguanylate cyclase
KE3_RS02050	COG5002	protein histidine kinase activity
KE3_RS02055	COG0463	Glycosyl transferase, family 2
KE3_RS02075	COG0195	Participates in both transcription termination and antitermination
KE3_RS02080	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KE3_RS02090	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KE3_RS02095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KE3_RS02100	COG1611	Belongs to the LOG family
KE3_RS02115	COG2217	Heavy metal translocating P-type atpase
KE3_RS02125	COG2860	membrane
KE3_RS02130	COG0561	phosphatase activity
KE3_RS02145	COG2826	transposase and inactivated derivatives, IS30 family
KE3_RS02160	COG1283	sodium-dependent phosphate transmembrane transporter activity
KE3_RS02200	COG1131	(ABC) transporter
KE3_RS02210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KE3_RS02220	COG0275	rRNA processing
KE3_RS02230	COG0768	penicillin binding
KE3_RS02235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KE3_RS02240	COG0513	Belongs to the DEAD box helicase family
KE3_RS02255	COG1126	abc transporter atp-binding protein
KE3_RS02265	COG0492	ferredoxin-NADP+ reductase activity
KE3_RS02270	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KE3_RS02280	COG3579	cysteine-type endopeptidase activity
KE3_RS02285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KE3_RS02290	COG3331	DNA recombination
KE3_RS02300	COG3599	regulation of cell shape
KE3_RS02310	COG0116	Belongs to the methyltransferase superfamily
KE3_RS02325	COG1854	S-ribosylhomocysteine lyase activity
KE3_RS02345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KE3_RS02355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KE3_RS02355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KE3_RS02365	COG2815	serine threonine protein kinase
KE3_RS02365	COG0515	serine threonine protein kinase
KE3_RS02375	COG4585	Histidine kinase
KE3_RS02380	COG2197	response regulator
KE3_RS02390	COG1098	S1 RNA binding domain
KE3_RS02400	COG1739	Uncharacterized protein family UPF0029
KE3_RS02405	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KE3_RS02410	COG1040	competence protein
KE3_RS02480	COG3557	Belongs to the UPF0374 family
KE3_RS02485	COG2137	regulation of response to DNA damage stimulus
KE3_RS02495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KE3_RS02510	COG1428	Deoxynucleoside kinase
KE3_RS02535	COG0525	valine-tRNA ligase activity
KE3_RS02545	COG4716	Myosin-crossreactive antigen
KE3_RS02585	COG0742	ribosomal rna small subunit methyltransferase
KE3_RS02590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KE3_RS02595	COG3480	Lon protease (S16) C-terminal proteolytic domain
KE3_RS02605	COG0737	Belongs to the 5'-nucleotidase family
KE3_RS02610	COG4470	Protein conserved in bacteria
KE3_RS02650	COG0134	indole-3-glycerol-phosphate synthase activity
KE3_RS02655	COG0135	phosphoribosylanthranilate isomerase activity
KE3_RS02670	COG1914	H( )-stimulated, divalent metal cation uptake system
KE3_RS02680	COG0783	Belongs to the Dps family
KE3_RS02690	COG1940	carbohydrate kinase activity
KE3_RS02695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KE3_RS02705	COG1217	gtp-binding protein TYPA
KE3_RS02755	COG2826	transposase and inactivated derivatives, IS30 family
KE3_RS02775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KE3_RS02780	COG1799	cell septum assembly
KE3_RS02795	COG3599	regulation of cell shape
KE3_RS02815	COG0542	response to heat
KE3_RS02830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KE3_RS02835	COG4703	Protein of unknown function (DUF1797)
KE3_RS02840	COG0765	amino acid transport
KE3_RS02855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KE3_RS02855	COG1918	ferrous iron import across plasma membrane
KE3_RS02870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KE3_RS02885	COG1376	ErfK ybiS ycfS ynhG family protein
KE3_RS02905	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KE3_RS02910	COG1438	arginine binding
KE3_RS02915	COG0497	DNA recombination
KE3_RS02920	COG1307	EDD domain protein, DegV family
KE3_RS02925	COG2755	lipolytic protein G-D-S-L family
KE3_RS02930	COG4698	Protein conserved in bacteria
KE3_RS02945	COG3104	oligopeptide transport
KE3_RS02950	COG0167	dihydroorotate dehydrogenase activity
KE3_RS02955	COG0640	Transcriptional regulator
KE3_RS02960	COG2217	Heavy metal translocating P-type atpase
KE3_RS02965	COG0588	phosphoglycerate mutase activity
KE3_RS02970	COG1827	regulation of RNA biosynthetic process
KE3_RS02980	COG0768	penicillin binding
KE3_RS02985	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KE3_RS02995	COG1181	Belongs to the D-alanine--D-alanine ligase family
KE3_RS03000	COG2826	transposase and inactivated derivatives, IS30 family
KE3_RS03010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KE3_RS03025	COG0513	Belongs to the DEAD box helicase family
KE3_RS03035	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KE3_RS03040	COG0204	Acyl-transferase
KE3_RS03045	COG1555	photosystem II stabilization
KE3_RS03045	COG1596	polysaccharide export
KE3_RS03050	COG0658	competence protein
KE3_RS03050	COG2333	competence protein COMEC
KE3_RS03055	COG1466	dna polymerase III delta subunit
KE3_RS03060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KE3_RS03065	COG0217	transcriptional regulatory protein
KE3_RS03070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KE3_RS03080	COG0363	glucosamine-6-phosphate deaminase activity
KE3_RS03085	COG1187	pseudouridine synthase activity
KE3_RS03105	COG0546	phosphoglycolate phosphatase activity
KE3_RS03110	COG4122	O-methyltransferase activity
KE3_RS03120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KE3_RS03130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KE3_RS03135	COG0436	Aminotransferase
KE3_RS03150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KE3_RS03155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KE3_RS03160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KE3_RS03170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KE3_RS03170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KE3_RS03180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KE3_RS03180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KE3_RS03190	COG3859	Proton-coupled thiamine transporter YuaJ
KE3_RS03195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KE3_RS03200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KE3_RS03205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KE3_RS03210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KE3_RS03215	COG0372	Belongs to the citrate synthase family
KE3_RS03245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KE3_RS03250	COG0513	Belongs to the DEAD box helicase family
KE3_RS03275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KE3_RS03280	COG0066	3-isopropylmalate dehydratase activity
KE3_RS03285	COG1956	GAF domain-containing protein
KE3_RS03290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KE3_RS03305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KE3_RS03315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KE3_RS03320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KE3_RS03325	COG4109	DRTGG domain
KE3_RS03330	COG0024	Methionine aminopeptidase
KE3_RS03340	COG2246	polysaccharide biosynthetic process
KE3_RS03345	COG4708	membrane
KE3_RS03350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KE3_RS03355	COG1597	lipid kinase activity
KE3_RS03405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KE3_RS03435	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KE3_RS03440	COG1074	ATP-dependent DNA helicase activity
KE3_RS03465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KE3_RS03480	COG0300	oxidoreductase activity
KE3_RS03485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KE3_RS03485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KE3_RS03490	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KE3_RS03510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KE3_RS03515	COG2384	SAM-dependent methyltransferase
KE3_RS03525	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KE3_RS03535	COG1088	dTDP-glucose 4,6-dehydratase activity
KE3_RS03540	COG1051	belongs to the nudix hydrolase family
KE3_RS03545	COG0628	permease
KE3_RS03550	COG0457	Tetratricopeptide repeat
KE3_RS03560	COG0028	Belongs to the TPP enzyme family
KE3_RS03565	COG3527	Alpha-acetolactate decarboxylase
KE3_RS03570	COG0531	amino acid
KE3_RS03575	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KE3_RS03600	COG4120	Belongs to the binding-protein-dependent transport system permease family
KE3_RS03605	COG3842	ATPase activity
KE3_RS03620	COG0488	(ABC) transporter
KE3_RS03630	COG1132	(ABC) transporter
KE3_RS03635	COG1132	(ABC) transporter
KE3_RS03655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KE3_RS03665	COG0789	Transcriptional regulator
KE3_RS03695	COG1136	(ABC) transporter
KE3_RS03700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KE3_RS03705	COG1011	Hydrolase
KE3_RS03715	COG0583	DNA-binding transcription factor activity
KE3_RS03720	COG2855	membrane
KE3_RS03725	COG1012	belongs to the aldehyde dehydrogenase family
KE3_RS03730	COG0322	excinuclease ABC activity
KE3_RS03760	COG1573	uracil-dna glycosylase
KE3_RS03780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KE3_RS03810	COG1316	TRANSCRIPTIONal
KE3_RS03830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KE3_RS03870	COG1215	transferase activity, transferring glycosyl groups
KE3_RS03875	COG0562	UDP-galactopyranose mutase
KE3_RS03885	COG2244	polysaccharide biosynthetic process
KE3_RS03895	COG1091	dTDP-4-dehydrorhamnose reductase activity
KE3_RS03920	COG0167	dihydroorotate dehydrogenase activity
KE3_RS03925	COG0284	orotidine-5'-phosphate decarboxylase activity
KE3_RS03935	COG1881	PFAM PEBP family protein
KE3_RS03955	COG0187	DNA topoisomerase II activity
KE3_RS03960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KE3_RS03965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KE3_RS03985	COG0539	negative regulation of cytoplasmic translation
KE3_RS03995	COG1346	cytolysis
KE3_RS04000	COG1380	Effector of murein hydrolase LrgA
KE3_RS04015	COG1131	(ABC) transporter
KE3_RS04020	COG1725	Transcriptional regulator
KE3_RS04030	COG0205	6-phosphofructokinase activity
KE3_RS04035	COG0469	pyruvate kinase activity
KE3_RS04040	COG0681	Belongs to the peptidase S26 family
KE3_RS04050	COG2824	Alkylphosphonate utilization operon protein PhnA
KE3_RS04055	COG0765	amino acid transport
KE3_RS04060	COG1126	abc transporter atp-binding protein
KE3_RS04070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KE3_RS04075	COG1115	amino acid carrier protein
KE3_RS04090	COG0628	permease
KE3_RS04110	COG1104	cysteine desulfurase activity
KE3_RS04120	COG4116	CYTH
KE3_RS04125	COG2357	RelA SpoT domain protein
KE3_RS04135	COG0564	pseudouridine synthase activity
KE3_RS04140	COG0280	phosphate acetyltransferase
KE3_RS04145	COG4221	oxidoreductase activity
KE3_RS04155	COG0561	phosphatase activity
KE3_RS04160	COG2723	6-phospho-beta-galactosidase activity
KE3_RS04165	COG1136	(ABC) transporter
KE3_RS04185	COG2233	PERMEase
KE3_RS04210	COG0803	Belongs to the bacterial solute-binding protein 9 family
KE3_RS04290	COG1215	transferase activity, transferring glycosyl groups
KE3_RS04320	COG2801	Transposase and inactivated derivatives
KE3_RS04335	COG1216	Glycosyl transferase, family 2
KE3_RS04335	COG1442	glycosyl transferase family 8
KE3_RS04360	COG2801	Transposase and inactivated derivatives
KE3_RS04395	COG2801	Transposase and inactivated derivatives
KE3_RS04405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KE3_RS04410	COG2890	protein-(glutamine-N5) methyltransferase activity
KE3_RS04415	COG0009	L-threonylcarbamoyladenylate synthase
KE3_RS04420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KE3_RS04440	COG1132	(ABC) transporter
KE3_RS04455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KE3_RS04460	COG0508	dehydrogenase complex catalyzes the overall conversion of
KE3_RS04460	COG0022	dehydrogenase e1 component
KE3_RS04465	COG0508	dehydrogenase complex catalyzes the overall conversion of
KE3_RS04485	COG0095	Lipoate-protein ligase
KE3_RS04515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KE3_RS04520	COG1418	mRNA catabolic process
KE3_RS04530	COG0519	Catalyzes the synthesis of GMP from XMP
KE3_RS04530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KE3_RS04550	COG0534	Mate efflux family protein
KE3_RS04575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KE3_RS04600	COG1196	nuclear chromosome segregation
KE3_RS04605	COG2188	Transcriptional regulator
KE3_RS04615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KE3_RS04630	COG2720	vancomycin resistance protein
KE3_RS04640	COG1121	(ABC) transporter
KE3_RS04645	COG4974	Belongs to the 'phage' integrase family
KE3_RS04650	COG1395	domain, Protein
KE3_RS04655	COG2205	protein histidine kinase activity
KE3_RS04660	COG0745	RESPONSE REGULATOR receiver
KE3_RS04665	COG0577	efflux transmembrane transporter activity
KE3_RS04670	COG1136	(ABC) transporter
KE3_RS04695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KE3_RS04705	COG3764	Sortase (surface protein transpeptidase)
KE3_RS04775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KE3_RS04825	COG0542	response to heat
KE3_RS04830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KE3_RS04830	COG0551	DNA topoisomerase type I activity
KE3_RS04945	COG0270	DNA (cytosine-5-)-methyltransferase activity
KE3_RS04955	COG0758	DNA mediated transformation
KE3_RS04960	COG0110	maltose O-acetyltransferase activity
KE3_RS04965	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KE3_RS05005	COG1131	(ABC) transporter
KE3_RS05010	COG0488	(ABC) transporter
KE3_RS05025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KE3_RS05030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KE3_RS05035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KE3_RS05040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KE3_RS05050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KE3_RS05055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KE3_RS05060	COG4684	Psort location CytoplasmicMembrane, score
KE3_RS05065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KE3_RS05085	COG0346	lactoylglutathione lyase activity
KE3_RS05090	COG3764	Sortase (surface protein transpeptidase)
KE3_RS05110	COG1079	Belongs to the binding-protein-dependent transport system permease family
KE3_RS05115	COG4603	Belongs to the binding-protein-dependent transport system permease family
KE3_RS05120	COG3845	ABC transporter
KE3_RS05125	COG1744	ABC transporter substrate-binding protein PnrA-like
KE3_RS05135	COG2813	Specifically methylates the guanine in position
KE3_RS05140	COG1072	(Pantothenic acid kinase))
KE3_RS05155	COG2801	Transposase and inactivated derivatives
KE3_RS05160	COG5002	protein histidine kinase activity
KE3_RS05165	COG0745	RESPONSE REGULATOR receiver
KE3_RS05175	COG0704	Plays a role in the regulation of phosphate uptake
KE3_RS05180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KE3_RS05185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KE3_RS05190	COG0581	inorganic phosphate transmembrane transporter activity
KE3_RS05195	COG0573	inorganic phosphate transmembrane transporter activity
KE3_RS05205	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KE3_RS05205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KE3_RS05210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KE3_RS05230	COG0483	inositol monophosphate 1-phosphatase activity
KE3_RS05240	COG1393	Belongs to the ArsC family
KE3_RS05245	COG0196	riboflavin kinase activity
KE3_RS05250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KE3_RS05280	COG1136	(ABC) transporter
KE3_RS05280	COG0577	efflux transmembrane transporter activity
KE3_RS05300	COG0210	DNA helicase
KE3_RS05320	COG1115	amino acid carrier protein
KE3_RS05335	COG2801	Transposase and inactivated derivatives
KE3_RS05350	COG5002	protein histidine kinase activity
KE3_RS05355	COG0745	RESPONSE REGULATOR receiver
KE3_RS05360	COG0577	efflux transmembrane transporter activity
KE3_RS05365	COG1136	(ABC) transporter
KE3_RS05370	COG0577	efflux transmembrane transporter activity
KE3_RS05400	COG0561	phosphatase activity
KE3_RS05405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KE3_RS05415	COG1447	Phosphotransferase system cellobiose-specific component IIA
KE3_RS05420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KE3_RS05420	COG3711	transcriptional antiterminator
KE3_RS05425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KE3_RS05450	COG2723	6-phospho-beta-galactosidase activity
KE3_RS05465	COG2207	Transcriptional regulator
KE3_RS05470	COG2801	Transposase and inactivated derivatives
KE3_RS05500	COG1177	transmembrane transport
KE3_RS05505	COG1176	ABC-type spermidine putrescine transport system, permease component I
KE3_RS05515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KE3_RS05540	COG0285	dihydrofolate synthase activity
KE3_RS05550	COG2962	Rard protein
KE3_RS05590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KE3_RS05635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KE3_RS05640	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KE3_RS05645	COG3425	synthase
KE3_RS05660	COG1272	protein, Hemolysin III
KE3_RS05680	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KE3_RS05690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KE3_RS05695	COG1126	abc transporter atp-binding protein
KE3_RS05700	COG0765	amino acid transport
KE3_RS05705	COG0765	amino acid transport
KE3_RS05710	COG1126	abc transporter atp-binding protein
KE3_RS05715	COG0765	amino acid transport
KE3_RS05720	COG0765	amino acid transport
KE3_RS05725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KE3_RS05735	COG0583	DNA-binding transcription factor activity
KE3_RS05740	COG0656	L-ascorbic acid biosynthetic process
KE3_RS05745	COG5002	protein histidine kinase activity
KE3_RS05750	COG0745	RESPONSE REGULATOR receiver
KE3_RS05755	COG2357	RelA SpoT domain protein
KE3_RS05760	COG1132	(ABC) transporter
KE3_RS05775	COG0242	peptide deformylase activity
KE3_RS05785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KE3_RS05795	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KE3_RS05815	COG1132	(ABC) transporter
KE3_RS05830	COG0488	(ABC) transporter
KE3_RS05855	COG1705	Flagellar rod assembly protein muramidase FlgJ
KE3_RS05855	COG1388	LysM domain
KE3_RS05860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KE3_RS05865	COG0646	methionine synthase
KE3_RS05865	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KE3_RS05870	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KE3_RS05875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KE3_RS05875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KE3_RS05875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KE3_RS05880	COG1105	Belongs to the carbohydrate kinase PfkB family
KE3_RS05885	COG1349	DNA-binding transcription factor activity
KE3_RS05895	COG0492	ferredoxin-NADP+ reductase activity
KE3_RS05900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KE3_RS05910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KE3_RS05925	COG1837	Belongs to the UPF0109 family
KE3_RS05950	COG0577	efflux transmembrane transporter activity
KE3_RS05955	COG1136	(ABC) transporter
KE3_RS05970	COG0505	Belongs to the CarA family
KE3_RS05975	COG0540	Belongs to the ATCase OTCase family
KE3_RS05995	COG0564	pseudouridine synthase activity
KE3_RS06005	COG0583	DNA-binding transcription factor activity
KE3_RS06010	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KE3_RS06035	COG0301	tRNA thio-modification
KE3_RS06040	COG1104	cysteine desulfurase activity
KE3_RS06050	COG0285	dihydrofolate synthase activity
KE3_RS06065	COG0287	Prephenate dehydrogenase
KE3_RS06075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KE3_RS06080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KE3_RS06090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KE3_RS06095	COG1368	sulfuric ester hydrolase activity
KE3_RS06100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KE3_RS06105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KE3_RS06110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KE3_RS06115	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KE3_RS06135	COG2195	Cleaves the N-terminal amino acid of tripeptides
KE3_RS06150	COG3942	CHAP domain
KE3_RS06155	COG0463	Glycosyl transferase, family 2
KE3_RS06160	COG0438	transferase activity, transferring glycosyl groups
KE3_RS06170	COG1368	sulfuric ester hydrolase activity
KE3_RS06175	COG1216	Glycosyl transferase, family 2
KE3_RS06175	COG1442	glycosyl transferase family 8
KE3_RS06200	COG1216	Glycosyl transferase, family 2
KE3_RS06230	COG1442	glycosyl transferase family 8
KE3_RS06230	COG1216	Glycosyl transferase, family 2
KE3_RS06240	COG2151	metal-sulfur cluster biosynthetic enzyme
KE3_RS06245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KE3_RS06250	COG0358	DNA primase activity
KE3_RS06255	COG1970	mechanosensitive ion channel activity
KE3_RS06280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KE3_RS06290	COG0058	SHG alpha-glucan phosphorylase activity
KE3_RS06295	COG1640	4-alpha-glucanotransferase
KE3_RS06300	COG1609	Transcriptional regulator
KE3_RS06310	COG1175	transmembrane transport
KE3_RS06315	COG3833	ABC-type maltose transport systems, permease component
KE3_RS06320	COG2816	NAD+ diphosphatase activity
KE3_RS06330	COG0765	amino acid transport
KE3_RS06335	COG1126	abc transporter atp-binding protein
KE3_RS06355	COG1187	pseudouridine synthase activity
KE3_RS06360	COG4166	transmembrane transport
KE3_RS06365	COG4166	transmembrane transport
KE3_RS06370	COG0659	secondary active sulfate transmembrane transporter activity
KE3_RS06380	COG0590	tRNA wobble adenosine to inosine editing
KE3_RS06400	COG0456	acetyltransferase
KE3_RS06410	COG1396	sequence-specific DNA binding
KE3_RS06415	COG2608	mercury ion transmembrane transporter activity
KE3_RS06430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KE3_RS06445	COG1316	TRANSCRIPTIONal
KE3_RS06450	COG0077	Prephenate dehydratase
KE3_RS06455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KE3_RS06460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KE3_RS06465	COG0481	GTPase activity
KE3_RS06495	COG1518	maintenance of DNA repeat elements
KE3_RS06500	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KE3_RS06515	COG0647	UMP catabolic process
KE3_RS06525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KE3_RS06540	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KE3_RS06545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KE3_RS06550	COG3442	glutamine amidotransferase
KE3_RS06555	COG0148	phosphopyruvate hydratase activity
KE3_RS06570	COG1523	belongs to the glycosyl hydrolase 13 family
KE3_RS06585	COG0107	imidazoleglycerol-phosphate synthase activity
KE3_RS06595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KE3_RS06605	COG0560	Phosphoserine phosphatase
KE3_RS06610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KE3_RS06620	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KE3_RS06635	COG0187	DNA topoisomerase II activity
KE3_RS06645	COG0772	Belongs to the SEDS family
KE3_RS06660	COG0038	chloride channel
KE3_RS06665	COG1605	Chorismate mutase
KE3_RS06665	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KE3_RS06670	COG0398	Pfam SNARE associated Golgi protein
KE3_RS06680	COG0716	FMN binding
KE3_RS06690	COG1454	alcohol dehydrogenase
KE3_RS06695	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KE3_RS06705	COG1705	Flagellar rod assembly protein muramidase FlgJ
KE3_RS06705	COG1388	LysM domain
KE3_RS06725	COG1598	PFAM Uncharacterised protein family UPF0150
KE3_RS06930	COG0629	single-stranded DNA binding
KE3_RS06985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KE3_RS07010	COG1309	transcriptional regulator
KE3_RS07020	COG0251	oxidation-reduction process
KE3_RS07040	COG0017	Asparaginyl-tRNA synthetase
KE3_RS07050	COG0436	Aminotransferase
KE3_RS07060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KE3_RS07060	COG1199	ATP-dependent helicase activity
KE3_RS07075	COG2177	Part of the ABC transporter FtsEX involved in
KE3_RS07080	COG2884	Cell division ATP-binding protein ftsE
KE3_RS07085	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KE3_RS07090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KE3_RS07110	COG1078	dGTPase activity
KE3_RS07135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KE3_RS07140	COG0772	Belongs to the SEDS family
KE3_RS07150	COG1164	Oligoendopeptidase f
KE3_RS07155	COG0386	Belongs to the glutathione peroxidase family
KE3_RS07175	COG0588	phosphoglycerate mutase activity
KE3_RS07200	COG0745	RESPONSE REGULATOR receiver
KE3_RS07210	COG0577	efflux transmembrane transporter activity
KE3_RS07210	COG1136	(ABC) transporter
KE3_RS07220	COG4443	Transcriptional Coactivator p15 (PC4)
KE3_RS07230	COG0826	peptidase U32
KE3_RS07275	COG2183	response to ionizing radiation
KE3_RS07285	COG0701	Predicted permease
KE3_RS07290	COG3689	TIGRFAM TIGR03943 family protein
KE3_RS07300	COG0552	protein localization to endoplasmic reticulum
KE3_RS07305	COG0561	phosphatase activity
KE3_RS07310	COG0561	phosphatase activity
KE3_RS07320	COG1196	nuclear chromosome segregation
KE3_RS07330	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KE3_RS07335	COG5002	protein histidine kinase activity
KE3_RS07340	COG0745	RESPONSE REGULATOR receiver
KE3_RS07345	COG1126	abc transporter atp-binding protein
KE3_RS07350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KE3_RS07355	COG0765	amino acid transport
KE3_RS07360	COG0765	amino acid transport
KE3_RS07375	COG3850	Histidine kinase
KE3_RS07375	COG5002	protein histidine kinase activity
KE3_RS07380	COG0745	RESPONSE REGULATOR receiver
KE3_RS07385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KE3_RS07400	COG4716	Myosin-crossreactive antigen
KE3_RS07410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KE3_RS07420	COG0438	transferase activity, transferring glycosyl groups
KE3_RS07430	COG1609	Transcriptional regulator
KE3_RS07435	COG0006	proline dipeptidase activity
KE3_RS07450	COG0778	Nitroreductase
KE3_RS07465	COG1846	Transcriptional regulator
KE3_RS07475	COG0557	exoribonuclease II activity
KE3_RS07485	COG2814	Major facilitator Superfamily
KE3_RS07490	COG0237	dephospho-CoA kinase activity
KE3_RS07495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KE3_RS07505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KE3_RS07510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KE3_RS07530	COG1702	phosphate starvation-inducible protein PhoH
KE3_RS07535	COG4479	Belongs to the UPF0346 family
KE3_RS07550	COG2996	Protein conserved in bacteria
KE3_RS07580	COG1674	ftsk spoiiie
KE3_RS07610	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KE3_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
KE3_RS07655	COG0640	Transcriptional regulator
KE3_RS07660	COG0708	Exodeoxyribonuclease III
KE3_RS07675	COG1393	Belongs to the ArsC family
KE3_RS07680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KE3_RS07705	COG1674	ftsk spoiiie
KE3_RS07710	COG2946	Replication initiation factor
KE3_RS07740	COG0741	lytic transglycosylase activity
KE3_RS07740	COG0791	NLP P60 protein
KE3_RS07790	COG0004	ammonium transporteR
KE3_RS07805	COG1774	PSP1 C-terminal conserved region
KE3_RS07810	COG0470	DNA polymerase III
KE3_RS07820	COG0517	IMP dehydrogenase activity
KE3_RS07820	COG1227	inorganic diphosphatase activity
KE3_RS07850	COG4471	UPF0298 protein
KE3_RS07870	COG0583	DNA-binding transcription factor activity
KE3_RS07880	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KE3_RS07885	COG0626	cystathionine gamma-synthase activity
KE3_RS07890	COG2244	polysaccharide biosynthetic process
KE3_RS07900	COG1120	ATPase activity
KE3_RS07905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KE3_RS07910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KE3_RS07915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KE3_RS07955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KE3_RS07960	COG1253	flavin adenine dinucleotide binding
KE3_RS07970	COG1119	ATPase activity
KE3_RS07975	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KE3_RS07980	COG1242	4 iron, 4 sulfur cluster binding
KE3_RS07985	COG0671	phosphoesterase, PA-phosphatase related
KE3_RS07990	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KE3_RS08000	COG0531	amino acid
KE3_RS08005	COG0569	domain protein
KE3_RS08010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KE3_RS08015	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KE3_RS08020	COG1187	pseudouridine synthase activity
KE3_RS08035	COG0582	viral genome integration into host DNA
KE3_RS08055	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KE3_RS08060	COG3763	UPF0154 protein
KE3_RS08080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KE3_RS08100	COG1254	Belongs to the acylphosphatase family
KE3_RS08115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KE3_RS08125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KE3_RS08145	COG1484	DNA-dependent DNA replication
KE3_RS08160	COG5002	protein histidine kinase activity
KE3_RS08165	COG0745	RESPONSE REGULATOR receiver
KE3_RS08175	COG0501	Belongs to the peptidase M48B family
KE3_RS08180	COG1704	LemA family
KE3_RS08190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KE3_RS08195	COG0569	domain protein
KE3_RS08200	COG2801	Transposase and inactivated derivatives
KE3_RS08215	COG1122	ATPase activity
KE3_RS08225	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KE3_RS08230	COG1114	Component of the transport system for branched-chain amino acids
KE3_RS08235	COG2910	NAD(P)H-binding
KE3_RS08260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KE3_RS08265	COG1473	amidohydrolase
KE3_RS08270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KE3_RS08275	COG0217	transcriptional regulatory protein
KE3_RS08290	COG2226	methyltransferase
KE3_RS08295	COG0799	negative regulation of ribosome biogenesis
KE3_RS08300	COG1335	isochorismatase
KE3_RS08305	COG1713	HD superfamily hydrolase involved in NAD metabolism
KE3_RS08310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KE3_RS08315	COG1534	Rna-binding protein
KE3_RS08320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KE3_RS08325	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KE3_RS08335	COG0477	Major facilitator Superfamily
KE3_RS08345	COG0697	spore germination
KE3_RS08360	COG0154	amidase activity
KE3_RS08365	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KE3_RS08370	COG1335	isochorismatase
KE3_RS08375	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KE3_RS08380	COG0436	Aminotransferase
KE3_RS08395	COG0561	phosphatase activity
KE3_RS08400	COG0252	asparaginase activity
KE3_RS08405	COG3655	Transcriptional regulator
KE3_RS08425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KE3_RS08430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KE3_RS08435	COG0736	holo-[acyl-carrier-protein] synthase activity
KE3_RS08440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KE3_RS08445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KE3_RS08455	COG1940	carbohydrate kinase activity
KE3_RS08460	COG2190	(PTS) system
KE3_RS08460	COG1263	PTS System
KE3_RS08460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KE3_RS08465	COG1621	beta-fructofuranosidase activity
KE3_RS08470	COG1609	Transcriptional regulator
KE3_RS08475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KE3_RS08485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KE3_RS08490	COG2131	deaminase
KE3_RS08500	COG0006	proline dipeptidase activity
KE3_RS08530	COG3655	Transcriptional regulator
KE3_RS08540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KE3_RS08580	COG1194	a g-specific adenine glycosylase
KE3_RS08610	COG3118	belongs to the thioredoxin family
KE3_RS08620	COG0157	Belongs to the NadC ModD family
KE3_RS08630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KE3_RS08650	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KE3_RS08655	COG0681	Belongs to the peptidase S26 family
KE3_RS08660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KE3_RS08675	COG1882	Formate acetyltransferase
KE3_RS08690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KE3_RS08710	COG5002	protein histidine kinase activity
KE3_RS08720	COG0704	Plays a role in the regulation of phosphate uptake
KE3_RS08725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KE3_RS08730	COG0581	inorganic phosphate transmembrane transporter activity
KE3_RS08735	COG0573	inorganic phosphate transmembrane transporter activity
KE3_RS08750	COG0789	Transcriptional regulator
KE3_RS08765	COG2081	HI0933 family
KE3_RS08790	COG0456	acetyltransferase
KE3_RS08795	COG1214	PFAM Peptidase M22, glycoprotease
KE3_RS08815	COG0493	'glutamate synthase
KE3_RS08820	COG0067	glutamate synthase
KE3_RS08820	COG0069	glutamate synthase activity
KE3_RS08820	COG0070	glutamate synthase
KE3_RS08825	COG0174	glutamine synthetase
KE3_RS08830	COG0789	Transcriptional regulator
KE3_RS08840	COG0126	phosphoglycerate kinase activity
KE3_RS08855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KE3_RS08860	COG0049	tRNA binding
KE3_RS08870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KE3_RS08890	COG1564	THIamine pyrophosphokinase
KE3_RS08895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KE3_RS08945	COG0084	hydrolase, TatD family'
KE3_RS08975	COG2801	Transposase and inactivated derivatives
KE3_RS09005	COG0281	malic enzyme
KE3_RS09010	COG0583	DNA-binding transcription factor activity
KE3_RS09015	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KE3_RS09020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KE3_RS09025	COG1696	Membrane protein involved in D-alanine export
KE3_RS09040	COG5002	protein histidine kinase activity
KE3_RS09045	COG0745	RESPONSE REGULATOR receiver
KE3_RS09050	COG2207	Transcriptional regulator
KE3_RS09055	COG2273	Hydrolase Family 16
KE3_RS09065	COG0395	ABC-type sugar transport system, permease component
KE3_RS09090	COG2273	Hydrolase Family 16
KE3_RS09115	COG1131	(ABC) transporter
KE3_RS09130	COG0594	ribonuclease P activity
KE3_RS09140	COG0137	argininosuccinate synthase activity
KE3_RS09145	COG2807	transmembrane transport
KE3_RS09150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KE3_RS09160	COG4989	oxidoreductase activity
KE3_RS09175	COG0756	dUTP diphosphatase activity
KE3_RS09190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KE3_RS09200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KE3_RS09210	COG2171	N-acyltransferase activity
KE3_RS09240	COG0166	Belongs to the GPI family
KE3_RS09250	COG1234	tRNA 3'-trailer cleavage
KE3_RS09255	COG1268	BioY protein
KE3_RS09260	COG0343	queuine tRNA-ribosyltransferase activity
KE3_RS09275	COG1832	CoA-binding protein
KE3_RS09280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KE3_RS09280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KE3_RS09305	COG2918	glutathione biosynthetic process
KE3_RS09305	COG1181	Belongs to the D-alanine--D-alanine ligase family
KE3_RS09320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KE3_RS09325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KE3_RS09330	COG0542	response to heat
KE3_RS09335	COG4463	regulation of RNA biosynthetic process
KE3_RS09345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KE3_RS09360	COG1619	proteins homologs of microcin C7 resistance protein MccF
KE3_RS09395	COG1396	sequence-specific DNA binding
KE3_RS09400	COG3590	peptidase
KE3_RS09435	COG0602	queuosine metabolic process
KE3_RS09445	COG1328	CTP reductase activity
KE3_RS09445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KE3_RS09465	COG4472	Bacterial protein of unknown function (DUF965)
KE3_RS09470	COG1393	Belongs to the ArsC family
KE3_RS09480	COG1546	Belongs to the CinA family
KE3_RS09480	COG1058	Belongs to the CinA family
KE3_RS09490	COG0519	Catalyzes the synthesis of GMP from XMP
KE3_RS09530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KE3_RS09535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KE3_RS09555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KE3_RS09565	COG4974	Belongs to the 'phage' integrase family
KE3_RS09615	COG1597	lipid kinase activity
KE3_RS09630	COG2261	transglycosylase associated protein
KE3_RS09650	COG3237	CsbD-like
KE3_RS09655	COG2801	Transposase and inactivated derivatives
KE3_RS09665	COG3759	membrane
KE3_RS09670	COG1511	domain protein
KE3_RS09675	COG1309	transcriptional regulator
KE3_RS09685	COG2826	transposase and inactivated derivatives, IS30 family
KE3_RS09695	COG4466	Protein conserved in bacteria
KE3_RS09700	COG0305	Participates in initiation and elongation during chromosome replication
KE3_RS09715	COG0445	tRNA wobble uridine modification
KE3_RS09725	COG1760	l-serine dehydratase
KE3_RS09730	COG1760	l-serine dehydratase
KE3_RS09740	COG0741	lytic transglycosylase activity
KE3_RS09830	COG1122	ATPase activity
KE3_RS09840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KE3_RS09850	COG0612	Peptidase, M16
KE3_RS09855	COG0612	Peptidase, M16
KE3_RS09865	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KE3_RS09875	COG0516	GMP reductase activity
KE3_RS09875	COG0517	IMP dehydrogenase activity
KE3_RS09890	COG0488	(ABC) transporter
KE3_RS09905	COG2801	Transposase and inactivated derivatives
KE3_RS09930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KE3_RS09935	COG1475	DNA binding
KE3_RS09945	COG2801	Transposase and inactivated derivatives
KE3_RS10060	COG1396	sequence-specific DNA binding