locus-tag	class	description
RN80_RS00040	COG4221	oxidoreductase activity
RN80_RS00045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RN80_RS00050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RN80_RS00065	COG0504	CTP synthase activity
RN80_RS00095	COG0525	valine-tRNA ligase activity
RN80_RS00105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RN80_RS00165	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RN80_RS00170	COG0195	Participates in both transcription termination and antitermination
RN80_RS00180	COG1472	Belongs to the glycosyl hydrolase 3 family
RN80_RS00195	COG1266	CAAX protease self-immunity
RN80_RS00235	COG3290	protein histidine kinase activity
RN80_RS00250	COG4473	ABC transporter
RN80_RS00255	COG1131	(ABC) transporter
RN80_RS00260	COG0537	adenosine 5'-monophosphoramidase activity
RN80_RS00275	COG0484	heat shock protein binding
RN80_RS00320	COG0732	type I restriction modification DNA specificity domain
RN80_RS00325	COG4974	Belongs to the 'phage' integrase family
RN80_RS00340	COG0174	glutamine synthetase
RN80_RS00345	COG0789	Transcriptional regulator
RN80_RS00365	COG1283	sodium-dependent phosphate transmembrane transporter activity
RN80_RS00375	COG1363	Peptidase, m42
RN80_RS00380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RN80_RS00385	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RN80_RS00390	COG4605	iron ion homeostasis
RN80_RS00395	COG4604	ABC transporter, ATP-binding protein
RN80_RS00400	COG4607	ABC-type enterochelin transport system periplasmic component
RN80_RS00410	COG2801	Transposase and inactivated derivatives
RN80_RS00420	COG1187	pseudouridine synthase activity
RN80_RS00450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RN80_RS00465	COG0366	Alpha amylase catalytic
RN80_RS00470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RN80_RS00475	COG4120	Belongs to the binding-protein-dependent transport system permease family
RN80_RS00485	COG4608	Belongs to the ABC transporter superfamily
RN80_RS00490	COG0444	Belongs to the ABC transporter superfamily
RN80_RS00495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RN80_RS00500	COG0601	transmembrane transport
RN80_RS00505	COG4166	transmembrane transport
RN80_RS00515	COG1253	flavin adenine dinucleotide binding
RN80_RS00530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RN80_RS00540	COG3480	Lon protease (S16) C-terminal proteolytic domain
RN80_RS00550	COG0742	ribosomal rna small subunit methyltransferase
RN80_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RN80_RS00570	COG1254	Belongs to the acylphosphatase family
RN80_RS00610	COG2801	Transposase and inactivated derivatives
RN80_RS00615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RN80_RS00625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RN80_RS00630	COG3481	metal-dependent phosphohydrolase, HD sub domain
RN80_RS00640	COG1564	THIamine pyrophosphokinase
RN80_RS00650	COG1162	GTPase activity
RN80_RS00665	COG1136	(ABC) transporter
RN80_RS00665	COG0577	efflux transmembrane transporter activity
RN80_RS00690	COG0084	hydrolase, TatD family'
RN80_RS00695	COG0531	amino acid
RN80_RS00705	COG4166	transmembrane transport
RN80_RS00715	COG0436	Aminotransferase
RN80_RS00725	COG0589	response to stress
RN80_RS00735	COG0561	phosphatase activity
RN80_RS00740	COG0252	asparaginase activity
RN80_RS00750	COG1609	Transcriptional regulator
RN80_RS00760	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RN80_RS00760	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RN80_RS00770	COG0285	dihydrofolate synthase activity
RN80_RS00775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RN80_RS00785	COG2252	PERMEase
RN80_RS00790	COG0561	phosphatase activity
RN80_RS00795	COG1064	alcohol dehydrogenase
RN80_RS00805	COG3715	PTS system
RN80_RS00810	COG3716	PTS system mannose fructose sorbose family IID component
RN80_RS00815	COG3579	cysteine-type endopeptidase activity
RN80_RS00825	COG1187	pseudouridine synthase activity
RN80_RS00830	COG2261	transglycosylase associated protein
RN80_RS00835	COG2309	aminopeptidase activity
RN80_RS00845	COG2176	DNA-directed DNA polymerase activity
RN80_RS00865	COG2197	response regulator
RN80_RS00870	COG4585	Histidine kinase
RN80_RS00875	COG0842	Transport permease protein
RN80_RS00880	COG1131	(ABC) transporter
RN80_RS00980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RN80_RS00985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RN80_RS01000	COG0577	efflux transmembrane transporter activity
RN80_RS01005	COG1136	(ABC) transporter
RN80_RS01015	COG1454	alcohol dehydrogenase
RN80_RS01015	COG1012	belongs to the aldehyde dehydrogenase family
RN80_RS01025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RN80_RS01035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RN80_RS01050	COG0706	membrane insertase activity
RN80_RS01095	COG4537	Required for transformation and DNA binding
RN80_RS01100	COG1459	type II secretion system
RN80_RS01105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RN80_RS01115	COG1063	alcohol dehydrogenase
RN80_RS01140	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
RN80_RS01145	COG3759	membrane
RN80_RS01160	COG0546	phosphoglycolate phosphatase activity
RN80_RS01165	COG0534	Mate efflux family protein
RN80_RS01275	COG0166	Belongs to the GPI family
RN80_RS01285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RN80_RS01290	COG1132	(ABC) transporter
RN80_RS01295	COG1132	(ABC) transporter
RN80_RS01305	COG1438	arginine binding
RN80_RS01325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RN80_RS01340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RN80_RS01355	COG0697	spore germination
RN80_RS01360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RN80_RS01360	COG4499	WXG100 protein secretion system (Wss), protein YukC
RN80_RS01370	COG2217	Heavy metal translocating P-type atpase
RN80_RS01380	COG2226	methyltransferase
RN80_RS01390	COG0058	SHG alpha-glucan phosphorylase activity
RN80_RS01395	COG1640	4-alpha-glucanotransferase
RN80_RS01400	COG2182	Extracellular solute-binding protein
RN80_RS01405	COG1175	transmembrane transport
RN80_RS01410	COG3833	ABC-type maltose transport systems, permease component
RN80_RS01415	COG5521	maltodextrose utilization protein MalA
RN80_RS01420	COG1609	Transcriptional regulator
RN80_RS01425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RN80_RS01465	COG1476	TRANSCRIPTIONal
RN80_RS01495	COG2151	metal-sulfur cluster biosynthetic enzyme
RN80_RS01510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RN80_RS01520	COG4372	Transposase
RN80_RS01520	COG1511	domain protein
RN80_RS01520	COG1196	nuclear chromosome segregation
RN80_RS01530	COG5002	protein histidine kinase activity
RN80_RS01545	COG1215	transferase activity, transferring glycosyl groups
RN80_RS01550	COG0569	domain protein
RN80_RS01555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RN80_RS01570	COG2514	catechol 2,3-dioxygenase activity
RN80_RS01610	COG2222	sugar isomerase
RN80_RS01620	COG3716	PTS system mannose fructose sorbose family IID component
RN80_RS01625	COG3715	PTS system
RN80_RS01630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RN80_RS01645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RN80_RS01670	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RN80_RS01675	COG0151	Belongs to the GarS family
RN80_RS01680	COG0138	bifunctional purine biosynthesis protein purh
RN80_RS01695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RN80_RS01700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RN80_RS01705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RN80_RS01710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RN80_RS01720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RN80_RS01725	COG2274	protein secretion by the type I secretion system
RN80_RS01785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RN80_RS01800	COG0436	Aminotransferase
RN80_RS01805	COG2855	membrane
RN80_RS01815	COG1832	CoA-binding protein
RN80_RS01820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RN80_RS01820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RN80_RS01865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RN80_RS01880	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RN80_RS01890	COG0756	dUTP diphosphatase activity
RN80_RS01950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RN80_RS01955	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RN80_RS01980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RN80_RS01985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RN80_RS01995	COG0012	GTP binding
RN80_RS02005	COG0592	DNA-directed DNA polymerase activity
RN80_RS02015	COG1475	DNA binding
RN80_RS02020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RN80_RS02065	COG1511	domain protein
RN80_RS02065	COG1511	domain protein
RN80_RS02075	COG0488	(ABC) transporter
RN80_RS02080	COG0180	Tryptophanyl-tRNA synthetase
RN80_RS02085	COG0517	IMP dehydrogenase activity
RN80_RS02085	COG0516	GMP reductase activity
RN80_RS02095	COG2501	S4 domain
RN80_RS02100	COG0612	Peptidase, M16
RN80_RS02105	COG0612	Peptidase, M16
RN80_RS02115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RN80_RS02120	COG1122	ATPase activity
RN80_RS02125	COG1122	ATPase activity
RN80_RS02130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RN80_RS02135	COG1792	Involved in formation and maintenance of cell shape
RN80_RS02145	COG3942	CHAP domain
RN80_RS02170	COG1739	Uncharacterized protein family UPF0029
RN80_RS02175	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RN80_RS02180	COG1040	competence protein
RN80_RS02200	COG0305	Participates in initiation and elongation during chromosome replication
RN80_RS02210	COG1388	LysM domain
RN80_RS02210	COG3942	CHAP domain
RN80_RS02220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RN80_RS02225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RN80_RS02230	COG1116	anion transmembrane transporter activity
RN80_RS02235	COG4463	regulation of RNA biosynthetic process
RN80_RS02240	COG0542	response to heat
RN80_RS02250	COG3201	nicotinamide mononucleotide transporter
RN80_RS02275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RN80_RS02285	COG2197	response regulator
RN80_RS02300	COG1136	(ABC) transporter
RN80_RS02315	COG1335	isochorismatase
RN80_RS02320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RN80_RS02340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RN80_RS02345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RN80_RS02360	COG1696	Membrane protein involved in D-alanine export
RN80_RS02370	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RN80_RS02375	COG1846	Transcriptional regulator
RN80_RS02380	COG1121	(ABC) transporter
RN80_RS02385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RN80_RS02390	COG0803	Belongs to the bacterial solute-binding protein 9 family
RN80_RS02390	COG3443	Belongs to the bacterial solute-binding protein 9 family
RN80_RS02395	COG1454	alcohol dehydrogenase
RN80_RS02405	COG3250	beta-galactosidase activity
RN80_RS02415	COG3537	Alpha-1,2-mannosidase
RN80_RS02425	COG0383	alpha-mannosidase activity
RN80_RS02440	COG4209	transmembrane transport
RN80_RS02445	COG0395	ABC-type sugar transport system, permease component
RN80_RS02450	COG1653	transport
RN80_RS02490	COG1695	Transcriptional regulator
RN80_RS02500	COG1216	Glycosyl transferase, family 2
RN80_RS02510	COG0546	phosphoglycolate phosphatase activity
RN80_RS02515	COG1760	l-serine dehydratase
RN80_RS02520	COG1760	l-serine dehydratase
RN80_RS02525	COG1388	LysM domain
RN80_RS02525	COG1705	Flagellar rod assembly protein muramidase FlgJ
RN80_RS02555	COG0494	nUDIX hydrolase
RN80_RS02560	COG0494	nUDIX hydrolase
RN80_RS02565	COG0445	tRNA wobble uridine modification
RN80_RS02595	COG1214	PFAM Peptidase M22, glycoprotease
RN80_RS02605	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RN80_RS02610	COG1396	sequence-specific DNA binding
RN80_RS02645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RN80_RS02650	COG1464	Belongs to the NlpA lipoprotein family
RN80_RS02655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RN80_RS02660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RN80_RS02680	COG2972	Histidine kinase
RN80_RS02685	COG2207	Transcriptional regulator
RN80_RS02685	COG4753	response regulator
RN80_RS02695	COG1780	Probably involved in ribonucleotide reductase function
RN80_RS02720	COG2818	Glycosylase
RN80_RS02725	COG2801	Transposase and inactivated derivatives
RN80_RS02760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RN80_RS02765	COG0006	proline dipeptidase activity
RN80_RS02770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RN80_RS02780	COG1393	Belongs to the ArsC family
RN80_RS02810	COG0285	dihydrofolate synthase activity
RN80_RS02825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RN80_RS02855	COG0602	queuosine metabolic process
RN80_RS02885	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RN80_RS02910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RN80_RS02930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RN80_RS02950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RN80_RS02965	COG0201	protein transport
RN80_RS02975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RN80_RS02980	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RN80_RS02990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RN80_RS02995	COG0202	RNA polymerase activity
RN80_RS03005	COG3830	Belongs to the UPF0237 family
RN80_RS03010	COG2848	UPF0210 protein
RN80_RS03020	COG1178	ABC-type Fe3 transport system permease component
RN80_RS03025	COG3842	ATPase activity
RN80_RS03030	COG1840	ABC-type Fe3 transport system, periplasmic component
RN80_RS03065	COG3279	Response regulator of the LytR AlgR family
RN80_RS03100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RN80_RS03105	COG4589	Belongs to the CDS family
RN80_RS03110	COG0750	zinc metalloprotease
RN80_RS03120	COG2723	6-phospho-beta-galactosidase activity
RN80_RS03125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RN80_RS03150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RN80_RS03155	COG0765	amino acid transport
RN80_RS03160	COG0765	amino acid transport
RN80_RS03165	COG1126	abc transporter atp-binding protein
RN80_RS03170	COG1523	belongs to the glycosyl hydrolase 13 family
RN80_RS03200	COG0802	atpase or kinase
RN80_RS03210	COG1316	TRANSCRIPTIONal
RN80_RS03245	COG1132	(ABC) transporter
RN80_RS03265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RN80_RS03275	COG1461	Dihydroxyacetone kinase
RN80_RS03280	COG0028	Belongs to the TPP enzyme family
RN80_RS03285	COG0440	acetolactate synthase activity
RN80_RS03295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RN80_RS03310	COG0765	amino acid transport
RN80_RS03325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RN80_RS03330	COG1882	Formate acetyltransferase
RN80_RS03340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RN80_RS03345	COG0569	domain protein
RN80_RS03360	COG1122	ATPase activity
RN80_RS03380	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
RN80_RS03385	COG0671	phosphoesterase, PA-phosphatase related
RN80_RS03395	COG1247	-acetyltransferase
RN80_RS03405	COG0456	acetyltransferase
RN80_RS03410	COG0072	phenylalanine-tRNA ligase activity
RN80_RS03410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RN80_RS03415	COG4152	abc transporter atp-binding protein
RN80_RS03420	COG1668	transmembrane transport
RN80_RS03425	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RN80_RS03435	COG0582	viral genome integration into host DNA
RN80_RS03440	COG1396	sequence-specific DNA binding
RN80_RS03475	COG2801	Transposase and inactivated derivatives
RN80_RS03490	COG2169	Transcriptional regulator
RN80_RS03500	COG2801	Transposase and inactivated derivatives
RN80_RS03510	COG4209	transmembrane transport
RN80_RS03515	COG0395	ABC-type sugar transport system, permease component
RN80_RS03520	COG1653	transport
RN80_RS03535	COG3104	oligopeptide transport
RN80_RS03540	COG3620	sequence-specific DNA binding
RN80_RS03545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RN80_RS03560	COG0386	Belongs to the glutathione peroxidase family
RN80_RS03590	COG4839	cell division protein FtsL
RN80_RS03595	COG0768	penicillin binding
RN80_RS03620	COG0366	Alpha amylase catalytic
RN80_RS03625	COG4166	transmembrane transport
RN80_RS03630	COG4166	transmembrane transport
RN80_RS03640	COG0562	UDP-galactopyranose mutase
RN80_RS03645	COG4166	transmembrane transport
RN80_RS03675	COG0116	Belongs to the methyltransferase superfamily
RN80_RS03685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RN80_RS03690	COG0745	RESPONSE REGULATOR receiver
RN80_RS03725	COG4585	Histidine kinase
RN80_RS03730	COG2197	response regulator
RN80_RS03755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RN80_RS03760	COG0681	Belongs to the peptidase S26 family
RN80_RS03785	COG1115	amino acid carrier protein
RN80_RS03810	COG0527	aspartate kinase activity
RN80_RS03815	COG1024	Enoyl-CoA hydratase
RN80_RS03830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RN80_RS03840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RN80_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
RN80_RS03850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RN80_RS03865	COG0439	Biotin carboxylase
RN80_RS03870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RN80_RS03920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RN80_RS03930	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
RN80_RS03935	COG0668	transmembrane transport
RN80_RS03950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RN80_RS03955	COG1534	Rna-binding protein
RN80_RS03960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RN80_RS03965	COG1713	HD superfamily hydrolase involved in NAD metabolism
RN80_RS03970	COG0799	negative regulation of ribosome biogenesis
RN80_RS03975	COG2226	methyltransferase
RN80_RS04000	COG0194	GDP metabolic process
RN80_RS04010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RN80_RS04020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RN80_RS04020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RN80_RS04025	COG0631	protein serine/threonine phosphatase activity
RN80_RS04030	COG2815	serine threonine protein kinase
RN80_RS04030	COG0515	serine threonine protein kinase
RN80_RS04045	COG3425	synthase
RN80_RS04055	COG1609	Transcriptional regulator
RN80_RS04060	COG1621	beta-fructofuranosidase activity
RN80_RS04070	COG1263	PTS System
RN80_RS04070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RN80_RS04070	COG2190	(PTS) system
RN80_RS04075	COG1940	carbohydrate kinase activity
RN80_RS04085	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
RN80_RS04105	COG0732	type I restriction modification DNA specificity domain
RN80_RS04135	COG3620	sequence-specific DNA binding
RN80_RS04140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RN80_RS04155	COG1045	serine acetyltransferase
RN80_RS04165	COG0215	cysteine-tRNA ligase activity
RN80_RS04170	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RN80_RS04180	COG3842	ATPase activity
RN80_RS04185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RN80_RS04190	COG0765	amino acid transport
RN80_RS04195	COG0765	amino acid transport
RN80_RS04200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RN80_RS04210	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RN80_RS04210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RN80_RS04260	COG1573	uracil-dna glycosylase
RN80_RS04270	COG1114	Component of the transport system for branched-chain amino acids
RN80_RS04275	COG1363	Peptidase, m42
RN80_RS04310	COG2226	methyltransferase
RN80_RS04325	COG3935	DnaD domain protein
RN80_RS04335	COG4193	domain, Protein
RN80_RS04335	COG5263	repeat protein
RN80_RS04345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RN80_RS04365	COG0251	oxidation-reduction process
RN80_RS04375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RN80_RS04385	COG0492	ferredoxin-NADP+ reductase activity
RN80_RS04390	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RN80_RS04410	COG1307	EDD domain protein, DegV family
RN80_RS04420	COG0617	tRNA 3'-terminal CCA addition
RN80_RS04425	COG0488	(ABC) transporter
RN80_RS04430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RN80_RS04440	COG0242	peptide deformylase activity
RN80_RS04455	COG3711	transcriptional antiterminator
RN80_RS04480	COG0436	Aminotransferase
RN80_RS04490	COG0017	Asparaginyl-tRNA synthetase
RN80_RS04505	COG0629	single-stranded DNA binding
RN80_RS04510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RN80_RS04525	COG1098	S1 RNA binding domain
RN80_RS04530	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RN80_RS04535	COG2827	Endonuclease containing a URI domain
RN80_RS04560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RN80_RS04565	COG2244	polysaccharide biosynthetic process
RN80_RS04570	COG4166	transmembrane transport
RN80_RS04580	COG0626	cystathionine gamma-synthase activity
RN80_RS04585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RN80_RS04590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RN80_RS04610	COG0456	acetyltransferase
RN80_RS04615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RN80_RS04625	COG1113	amino acid transport
RN80_RS04635	COG1131	(ABC) transporter
RN80_RS04655	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RN80_RS04665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RN80_RS04675	COG0785	Cytochrome C biogenesis protein
RN80_RS04680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RN80_RS04685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RN80_RS04685	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RN80_RS04690	COG4753	response regulator
RN80_RS04690	COG2207	Transcriptional regulator
RN80_RS04695	COG2972	Histidine kinase
RN80_RS04705	COG3064	Membrane
RN80_RS04715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RN80_RS04730	COG1940	carbohydrate kinase activity
RN80_RS04750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RN80_RS04755	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
RN80_RS04765	COG0300	oxidoreductase activity
RN80_RS04775	COG4193	domain, Protein
RN80_RS04775	COG5263	repeat protein
RN80_RS04815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RN80_RS04825	COG1187	pseudouridine synthase activity
RN80_RS04830	COG1217	gtp-binding protein TYPA
RN80_RS04845	COG1136	(ABC) transporter
RN80_RS04860	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RN80_RS04880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RN80_RS04885	COG1126	abc transporter atp-binding protein
RN80_RS04890	COG4215	(ABC) transporter
RN80_RS04900	COG1304	FMN binding
RN80_RS04915	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RN80_RS04920	COG0352	thiamine-phosphate diphosphorylase activity
RN80_RS04930	COG4172	Belongs to the ABC transporter superfamily
RN80_RS04940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RN80_RS04950	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RN80_RS04955	COG0352	thiamine-phosphate diphosphorylase activity
RN80_RS04975	COG2217	Heavy metal translocating P-type atpase
RN80_RS04980	COG0028	Belongs to the TPP enzyme family
RN80_RS05000	COG2723	6-phospho-beta-galactosidase activity
RN80_RS05005	COG1482	cell wall glycoprotein biosynthetic process
RN80_RS05010	COG0733	neurotransmitter:sodium symporter activity
RN80_RS05015	COG0789	Transcriptional regulator
RN80_RS05020	COG2081	HI0933 family
RN80_RS05025	COG1307	EDD domain protein, DegV family
RN80_RS05035	COG2131	deaminase
RN80_RS05040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RN80_RS05080	COG0517	IMP dehydrogenase activity
RN80_RS05080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RN80_RS05080	COG0617	tRNA 3'-terminal CCA addition
RN80_RS05085	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RN80_RS05090	COG2884	Cell division ATP-binding protein ftsE
RN80_RS05095	COG2177	Part of the ABC transporter FtsEX involved in
RN80_RS05100	COG2190	(PTS) system
RN80_RS05100	COG1263	PTS System
RN80_RS05100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RN80_RS05110	COG0513	Belongs to the DEAD box helicase family
RN80_RS05155	COG0726	polysaccharide deacetylase
RN80_RS05160	COG0656	L-ascorbic acid biosynthetic process
RN80_RS05185	COG3976	FMN-binding domain protein
RN80_RS05185	COG1053	succinate dehydrogenase
RN80_RS05185	COG0431	NADPH-dependent FMN reductase
RN80_RS05215	COG1272	protein, Hemolysin III
RN80_RS05230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RN80_RS05235	COG1393	Belongs to the ArsC family
RN80_RS05245	COG1126	abc transporter atp-binding protein
RN80_RS05255	COG0492	ferredoxin-NADP+ reductase activity
RN80_RS05280	COG0561	phosphatase activity
RN80_RS05310	COG1349	DNA-binding transcription factor activity
RN80_RS05315	COG1105	Belongs to the carbohydrate kinase PfkB family
RN80_RS05320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RN80_RS05320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RN80_RS05320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RN80_RS05325	COG0697	spore germination
RN80_RS05325	COG1674	ftsk spoiiie
RN80_RS05335	COG1104	cysteine desulfurase activity
RN80_RS05365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RN80_RS05375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RN80_RS05380	COG0697	spore germination
RN80_RS05385	COG2188	Transcriptional regulator
RN80_RS05400	COG0826	peptidase U32
RN80_RS05410	COG0356	it plays a direct role in the translocation of protons across the membrane
RN80_RS05445	COG2706	6-phosphogluconolactonase activity
RN80_RS05450	COG4166	transmembrane transport
RN80_RS05455	COG0628	permease
RN80_RS05470	COG1126	abc transporter atp-binding protein
RN80_RS05490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RN80_RS05505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RN80_RS05510	COG0494	nUDIX hydrolase
RN80_RS05520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RN80_RS05530	COG2176	DNA-directed DNA polymerase activity
RN80_RS05535	COG0584	glycerophosphoryl diester phosphodiesterase
RN80_RS05580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RN80_RS05585	COG0716	FMN binding
RN80_RS05590	COG1605	Chorismate mutase
RN80_RS05590	COG0077	Prephenate dehydratase
RN80_RS05595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RN80_RS05600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RN80_RS05635	COG1078	dGTPase activity
RN80_RS05655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RN80_RS05670	COG1704	LemA family
RN80_RS05685	COG0488	(ABC) transporter
RN80_RS05695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RN80_RS05710	COG0505	Belongs to the CarA family
RN80_RS05720	COG3475	LICD family
RN80_RS05725	COG3475	LICD family
RN80_RS05740	COG1063	alcohol dehydrogenase
RN80_RS05755	COG4750	Nucleotidyl transferase
RN80_RS05760	COG0758	DNA mediated transformation
RN80_RS05765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RN80_RS05775	COG2832	Protein of unknown function (DUF454)
RN80_RS05780	COG3142	Participates in the control of copper homeostasis
RN80_RS05795	COG0473	3-isopropylmalate dehydrogenase activity
RN80_RS05820	COG1401	restriction endodeoxyribonuclease activity
RN80_RS05845	COG1196	nuclear chromosome segregation
RN80_RS05855	COG0196	riboflavin kinase activity
RN80_RS05860	COG3689	TIGRFAM TIGR03943 family protein
RN80_RS05865	COG0701	Predicted permease
RN80_RS05875	COG2183	response to ionizing radiation
RN80_RS05890	COG1136	(ABC) transporter
RN80_RS05895	COG0577	efflux transmembrane transporter activity
RN80_RS05905	COG0561	phosphatase activity
RN80_RS05910	COG0561	phosphatase activity
RN80_RS05915	COG0552	protein localization to endoplasmic reticulum
RN80_RS05920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RN80_RS05925	COG1126	abc transporter atp-binding protein
RN80_RS05930	COG0765	amino acid transport
RN80_RS05940	COG0556	nucleotide-excision repair
RN80_RS05955	COG2816	NAD+ diphosphatase activity
RN80_RS05960	COG1827	regulation of RNA biosynthetic process
RN80_RS05970	COG4684	Psort location CytoplasmicMembrane, score
RN80_RS05975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RN80_RS05990	COG0210	DNA helicase
RN80_RS06000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RN80_RS06020	COG1104	cysteine desulfurase activity
RN80_RS06025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RN80_RS06035	COG2357	RelA SpoT domain protein
RN80_RS06045	COG0564	pseudouridine synthase activity
RN80_RS06050	COG0280	phosphate acetyltransferase
RN80_RS06055	COG1194	a g-specific adenine glycosylase
RN80_RS06060	COG0745	RESPONSE REGULATOR receiver
RN80_RS06070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RN80_RS06080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RN80_RS06085	COG0488	(ABC) transporter
RN80_RS06105	COG1523	belongs to the glycosyl hydrolase 13 family
RN80_RS06110	COG1012	belongs to the aldehyde dehydrogenase family
RN80_RS06115	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RN80_RS06125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RN80_RS06135	COG0560	Phosphoserine phosphatase
RN80_RS06155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RN80_RS06165	COG4109	DRTGG domain
RN80_RS06170	COG0024	Methionine aminopeptidase
RN80_RS06175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RN80_RS06180	COG1307	EDD domain protein, DegV family
RN80_RS06185	COG0776	regulation of translation
RN80_RS06190	COG0785	Cytochrome C biogenesis protein
RN80_RS06195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RN80_RS06200	COG0531	amino acid
RN80_RS06205	COG0803	Belongs to the bacterial solute-binding protein 9 family
RN80_RS06205	COG3443	Belongs to the bacterial solute-binding protein 9 family
RN80_RS06235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RN80_RS06240	COG1970	mechanosensitive ion channel activity
RN80_RS06250	COG4708	membrane
RN80_RS06260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RN80_RS06270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RN80_RS06275	COG1942	4-Oxalocrotonate Tautomerase
RN80_RS06280	COG1435	thymidine kinase activity
RN80_RS06290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RN80_RS06295	COG2890	protein-(glutamine-N5) methyltransferase activity
RN80_RS06320	COG0741	lytic transglycosylase activity
RN80_RS06330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RN80_RS06340	COG1131	(ABC) transporter
RN80_RS06355	COG2188	Transcriptional regulator
RN80_RS06360	COG1309	transcriptional regulator
RN80_RS06370	COG1131	(ABC) transporter
RN80_RS06375	COG1132	(ABC) transporter
RN80_RS06410	COG1597	lipid kinase activity
RN80_RS06415	COG0135	phosphoribosylanthranilate isomerase activity
RN80_RS06420	COG0366	Alpha amylase catalytic
RN80_RS06435	COG1982	Orn Lys Arg decarboxylase major
RN80_RS06440	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RN80_RS06460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RN80_RS06465	COG0745	RESPONSE REGULATOR receiver
RN80_RS06470	COG2205	protein histidine kinase activity
RN80_RS06480	COG1131	(ABC) transporter
RN80_RS06485	COG0561	phosphatase activity
RN80_RS06505	COG4464	protein tyrosine phosphatase activity
RN80_RS06510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RN80_RS06520	COG0489	protein tyrosine kinase activity
RN80_RS06535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RN80_RS06540	COG0438	transferase activity, transferring glycosyl groups
RN80_RS06550	COG1216	Glycosyl transferase, family 2
RN80_RS06555	COG1215	transferase activity, transferring glycosyl groups
RN80_RS06560	COG1216	Glycosyl transferase, family 2
RN80_RS06565	COG1216	Glycosyl transferase, family 2
RN80_RS06565	COG1442	glycosyl transferase family 8
RN80_RS06585	COG0438	transferase activity, transferring glycosyl groups
RN80_RS06590	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RN80_RS06600	COG0038	chloride channel
RN80_RS06610	COG0095	Lipoate-protein ligase
RN80_RS06615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RN80_RS06620	COG0508	dehydrogenase complex catalyzes the overall conversion of
RN80_RS06625	COG0022	dehydrogenase e1 component
RN80_RS06630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RN80_RS06635	COG0534	Mate efflux family protein
RN80_RS06640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RN80_RS06645	COG1051	belongs to the nudix hydrolase family
RN80_RS06655	COG1011	Hydrolase
RN80_RS06680	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RN80_RS06685	COG1461	Dihydroxyacetone kinase
RN80_RS06690	COG2376	Dihydroxyacetone kinase
RN80_RS06695	COG1309	transcriptional regulator
RN80_RS06700	COG2376	Dihydroxyacetone kinase
RN80_RS06725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RN80_RS06730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RN80_RS06740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RN80_RS06775	COG3711	transcriptional antiterminator
RN80_RS06780	COG3684	Belongs to the aldolase LacD family
RN80_RS06805	COG3775	system Galactitol-specific IIC component
RN80_RS06825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RN80_RS06830	COG0497	DNA recombination
RN80_RS06835	COG1438	arginine binding
RN80_RS06840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RN80_RS06865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RN80_RS06900	COG3764	Sortase (surface protein transpeptidase)
RN80_RS06905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RN80_RS06915	COG0469	pyruvate kinase activity
RN80_RS06930	COG2936	dipeptidyl-peptidase activity
RN80_RS06935	COG1438	arginine binding
RN80_RS06955	COG1983	PspC domain protein
RN80_RS06960	COG0438	transferase activity, transferring glycosyl groups
RN80_RS06965	COG0438	transferase activity, transferring glycosyl groups
RN80_RS06970	COG2151	metal-sulfur cluster biosynthetic enzyme
RN80_RS06975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RN80_RS06980	COG0358	DNA primase activity
RN80_RS07000	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
RN80_RS07005	COG0772	Belongs to the SEDS family
RN80_RS07015	COG4122	O-methyltransferase activity
RN80_RS07030	COG3615	Tellurite resistance protein tehB
RN80_RS07030	COG0500	methyltransferase
RN80_RS07040	COG0557	exoribonuclease II activity
RN80_RS07050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RN80_RS07055	COG2814	Major facilitator Superfamily
RN80_RS07060	COG0237	dephospho-CoA kinase activity
RN80_RS07065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RN80_RS07075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RN80_RS07085	COG1293	RNA-binding protein homologous to eukaryotic snRNP
RN80_RS07090	COG5263	repeat protein
RN80_RS07090	COG4193	domain, Protein
RN80_RS07095	COG0167	dihydroorotate dehydrogenase activity
RN80_RS07100	COG0543	2 iron, 2 sulfur cluster binding
RN80_RS07130	COG1131	(ABC) transporter
RN80_RS07140	COG0658	competence protein
RN80_RS07140	COG2333	competence protein COMEC
RN80_RS07145	COG1596	polysaccharide export
RN80_RS07145	COG1555	photosystem II stabilization
RN80_RS07150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RN80_RS07155	COG1702	phosphate starvation-inducible protein PhoH
RN80_RS07165	COG0456	acetyltransferase
RN80_RS07165	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RN80_RS07170	COG2996	Protein conserved in bacteria
RN80_RS07180	COG0528	UMP kinase activity
RN80_RS07200	COG0470	DNA polymerase III
RN80_RS07210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RN80_RS07225	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RN80_RS07230	COG0564	pseudouridine synthase activity
RN80_RS07235	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RN80_RS07240	COG0583	DNA-binding transcription factor activity
RN80_RS07295	COG0628	permease
RN80_RS07300	COG1686	Belongs to the peptidase S11 family
RN80_RS07310	COG0719	Fe-S assembly protein
RN80_RS07320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RN80_RS07325	COG0719	Fe-S assembly protein
RN80_RS07340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RN80_RS07345	COG1956	GAF domain-containing protein
RN80_RS07350	COG0539	negative regulation of cytoplasmic translation
RN80_RS07370	COG4166	transmembrane transport
RN80_RS07375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RN80_RS07380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RN80_RS07400	COG2184	nucleotidyltransferase activity
RN80_RS07415	COG0187	DNA topoisomerase II activity
RN80_RS07425	COG1079	Belongs to the binding-protein-dependent transport system permease family
RN80_RS07430	COG4603	Belongs to the binding-protein-dependent transport system permease family
RN80_RS07435	COG3845	ABC transporter
RN80_RS07440	COG1744	ABC transporter substrate-binding protein PnrA-like
RN80_RS07445	COG0295	cytidine deaminase activity
RN80_RS07455	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RN80_RS07460	COG2813	Specifically methylates the guanine in position
RN80_RS07485	COG0813	purine-nucleoside phosphorylase activity
RN80_RS07495	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RN80_RS07520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RN80_RS07530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RN80_RS07535	COG1126	abc transporter atp-binding protein
RN80_RS07540	COG0765	amino acid transport
RN80_RS07545	COG4703	Protein of unknown function (DUF1797)
RN80_RS07550	COG0542	response to heat
RN80_RS07570	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
RN80_RS07575	COG0187	DNA topoisomerase II activity
RN80_RS07585	COG0693	protein deglycase activity
RN80_RS07590	COG0772	Belongs to the SEDS family
RN80_RS07595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RN80_RS07595	COG1199	ATP-dependent helicase activity
RN80_RS07620	COG5002	protein histidine kinase activity
RN80_RS07625	COG0745	RESPONSE REGULATOR receiver
RN80_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
RN80_RS07665	COG4989	oxidoreductase activity
RN80_RS07680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RN80_RS07680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RN80_RS07685	COG0577	efflux transmembrane transporter activity
RN80_RS07690	COG1136	(ABC) transporter
RN80_RS07695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RN80_RS07700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RN80_RS07705	COG1268	BioY protein
RN80_RS07710	COG4443	Transcriptional Coactivator p15 (PC4)
RN80_RS07720	COG1328	CTP reductase activity
RN80_RS07720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RN80_RS07740	COG2267	carboxylic ester hydrolase activity
RN80_RS07745	COG0697	spore germination
RN80_RS07785	COG0464	growth
RN80_RS07800	COG0488	(ABC) transporter
RN80_RS07810	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RN80_RS07815	COG4470	Protein conserved in bacteria
RN80_RS07820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RN80_RS07830	COG0167	dihydroorotate dehydrogenase activity
RN80_RS07835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RN80_RS07840	COG1309	transcriptional regulator
RN80_RS07845	COG0604	alcohol dehydrogenase
RN80_RS07855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RN80_RS07860	COG0402	S-adenosylhomocysteine deaminase activity
RN80_RS07875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RN80_RS07875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RN80_RS07905	COG1215	transferase activity, transferring glycosyl groups
RN80_RS07915	COG3475	LICD family
RN80_RS07925	COG0077	Prephenate dehydratase
RN80_RS07930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RN80_RS07945	COG0287	Prephenate dehydrogenase
RN80_RS07970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RN80_RS07975	COG1368	sulfuric ester hydrolase activity
RN80_RS07985	COG4555	ABC transporter
RN80_RS08030	COG3842	ATPase activity
RN80_RS08045	COG3527	Alpha-acetolactate decarboxylase
RN80_RS08050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RN80_RS08055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RN80_RS08065	COG0704	Plays a role in the regulation of phosphate uptake
RN80_RS08070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RN80_RS08075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RN80_RS08080	COG0581	inorganic phosphate transmembrane transporter activity
RN80_RS08085	COG0573	inorganic phosphate transmembrane transporter activity
RN80_RS08090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RN80_RS08095	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
RN80_RS08095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RN80_RS08100	COG0483	inositol monophosphate 1-phosphatase activity
RN80_RS08110	COG1393	Belongs to the ArsC family
RN80_RS08120	COG0647	UMP catabolic process
RN80_RS08130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RN80_RS08155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RN80_RS08190	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RN80_RS08195	COG1242	4 iron, 4 sulfur cluster binding
RN80_RS08230	COG4555	ABC transporter
RN80_RS08235	COG0191	fructose-bisphosphate aldolase activity
RN80_RS08240	COG5002	protein histidine kinase activity
RN80_RS08245	COG0745	RESPONSE REGULATOR receiver
RN80_RS08255	COG0577	efflux transmembrane transporter activity
RN80_RS08260	COG1136	(ABC) transporter
RN80_RS08265	COG0577	efflux transmembrane transporter activity
RN80_RS08275	COG1335	isochorismatase
RN80_RS08280	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RN80_RS08285	COG0513	Belongs to the DEAD box helicase family
RN80_RS08290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RN80_RS08295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RN80_RS08300	COG3442	glutamine amidotransferase
RN80_RS08305	COG0006	proline dipeptidase activity
RN80_RS08310	COG0513	Belongs to the DEAD box helicase family
RN80_RS08315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RN80_RS08320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RN80_RS08325	COG3442	glutamine amidotransferase
RN80_RS08330	COG0006	proline dipeptidase activity
RN80_RS08335	COG4720	Psort location CytoplasmicMembrane, score
RN80_RS08340	COG0351	phosphomethylpyrimidine kinase
RN80_RS08360	COG2824	Alkylphosphonate utilization operon protein PhnA
RN80_RS08375	COG0463	Glycosyl transferase, family 2
RN80_RS08380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RN80_RS08385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RN80_RS08390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RN80_RS08395	COG2384	SAM-dependent methyltransferase
RN80_RS08400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RN80_RS08405	COG0204	Acyl-transferase
RN80_RS08425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RN80_RS08455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RN80_RS08470	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
RN80_RS08475	COG5002	protein histidine kinase activity
RN80_RS08480	COG0745	RESPONSE REGULATOR receiver
RN80_RS08495	COG1959	2 iron, 2 sulfur cluster binding
RN80_RS08540	COG0860	N-Acetylmuramoyl-L-alanine amidase
RN80_RS08540	COG2247	cell wall binding repeat
RN80_RS08550	COG3590	peptidase
RN80_RS08570	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
RN80_RS08580	COG1136	(ABC) transporter
RN80_RS08580	COG0577	efflux transmembrane transporter activity
RN80_RS08610	COG3599	regulation of cell shape
RN80_RS08630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RN80_RS08650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RN80_RS08665	COG0768	penicillin binding
RN80_RS08700	COG1131	(ABC) transporter
RN80_RS08730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RN80_RS08740	COG2731	YhcH YjgK YiaL family protein
RN80_RS08745	COG0395	ABC-type sugar transport system, permease component
RN80_RS08750	COG1175	transmembrane transport
RN80_RS08770	COG3458	cephalosporin-C deacetylase activity
RN80_RS08775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RN80_RS08785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RN80_RS08800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RN80_RS08805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RN80_RS08840	COG1484	DNA-dependent DNA replication
RN80_RS08855	COG1725	Transcriptional regulator
RN80_RS08860	COG1131	(ABC) transporter
RN80_RS08905	COG1346	cytolysis
RN80_RS08925	COG3118	belongs to the thioredoxin family
RN80_RS08935	COG0720	synthase
RN80_RS08950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RN80_RS08965	COG1733	regulation of RNA biosynthetic process
RN80_RS08975	COG1164	Oligoendopeptidase f
RN80_RS08980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RN80_RS08985	COG2264	protein methyltransferase activity
RN80_RS08995	COG1051	belongs to the nudix hydrolase family
RN80_RS09015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RN80_RS09025	COG4974	Belongs to the 'phage' integrase family
RN80_RS09080	COG0628	permease
RN80_RS09090	COG1959	2 iron, 2 sulfur cluster binding
RN80_RS09095	COG1063	alcohol dehydrogenase
RN80_RS09110	COG1621	beta-fructofuranosidase activity
RN80_RS09115	COG0395	ABC-type sugar transport system, permease component
RN80_RS09120	COG1175	transmembrane transport
RN80_RS09130	COG1609	Transcriptional regulator
RN80_RS09135	COG3711	transcriptional antiterminator
RN80_RS09140	COG2261	transglycosylase associated protein
RN80_RS09160	COG3237	CsbD-like
RN80_RS09175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RN80_RS09190	COG0135	phosphoribosylanthranilate isomerase activity
RN80_RS09205	COG0512	Glutamine amidotransferase of anthranilate synthase
RN80_RS09210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RN80_RS09220	COG0133	tryptophan synthase activity
RN80_RS09230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RN80_RS09235	COG1132	(ABC) transporter
RN80_RS09240	COG1132	(ABC) transporter
RN80_RS09255	COG0708	Exodeoxyribonuclease III
RN80_RS09270	COG2233	PERMEase
RN80_RS09285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RN80_RS09290	COG1609	Transcriptional regulator
RN80_RS09300	COG0789	Transcriptional regulator
RN80_RS09305	COG1230	cation diffusion facilitator family transporter
RN80_RS09310	COG1309	transcriptional regulator
RN80_RS09340	COG1122	ATPase activity
RN80_RS09350	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RN80_RS09360	COG1174	glycine betaine transport
RN80_RS09380	COG0366	Alpha amylase catalytic
RN80_RS09385	COG0395	ABC-type sugar transport system, permease component
RN80_RS09390	COG1175	transmembrane transport
RN80_RS09395	COG1653	transport
RN80_RS09400	COG3345	alpha-galactosidase
RN80_RS09405	COG2207	Transcriptional regulator
RN80_RS09410	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RN80_RS09410	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon