locus-tag	class	description
JJN14_RS00010	COG0592	DNA-directed DNA polymerase activity
JJN14_RS00020	COG0012	GTP binding
JJN14_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JJN14_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JJN14_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JJN14_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JJN14_RS00130	COG0756	dUTP diphosphatase activity
JJN14_RS00140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JJN14_RS00160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JJN14_RS00165	COG1832	CoA-binding protein
JJN14_RS00170	COG2855	membrane
JJN14_RS00175	COG0436	Aminotransferase
JJN14_RS00190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JJN14_RS00205	COG0438	transferase activity, transferring glycosyl groups
JJN14_RS00220	COG2274	protein secretion by the type I secretion system
JJN14_RS00225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JJN14_RS00240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JJN14_RS00245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JJN14_RS00250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JJN14_RS00255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JJN14_RS00265	COG0138	bifunctional purine biosynthesis protein purh
JJN14_RS00270	COG0151	Belongs to the GarS family
JJN14_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JJN14_RS00295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JJN14_RS00300	COG3583	domain protein
JJN14_RS00300	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JJN14_RS00300	COG3064	Membrane
JJN14_RS00315	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJN14_RS00320	COG3715	PTS system
JJN14_RS00325	COG3716	PTS system mannose fructose sorbose family IID component
JJN14_RS00335	COG2222	sugar isomerase
JJN14_RS00345	COG3583	domain protein
JJN14_RS00380	COG2514	catechol 2,3-dioxygenase activity
JJN14_RS00385	COG1937	Protein conserved in bacteria
JJN14_RS00390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JJN14_RS00390	COG0425	Belongs to the sulfur carrier protein TusA family
JJN14_RS00395	COG0446	pyridine nucleotide-disulphide oxidoreductase
JJN14_RS00400	COG0425	Belongs to the sulfur carrier protein TusA family
JJN14_RS00400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JJN14_RS00410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JJN14_RS00415	COG0569	domain protein
JJN14_RS00430	COG5002	protein histidine kinase activity
JJN14_RS00465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JJN14_RS00480	COG2151	metal-sulfur cluster biosynthetic enzyme
JJN14_RS00495	COG0124	histidyl-tRNA synthetase
JJN14_RS00505	COG1476	TRANSCRIPTIONal
JJN14_RS00545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JJN14_RS00550	COG1609	Transcriptional regulator
JJN14_RS00555	COG5521	maltodextrose utilization protein MalA
JJN14_RS00560	COG3833	ABC-type maltose transport systems, permease component
JJN14_RS00565	COG1175	transmembrane transport
JJN14_RS00570	COG2182	Extracellular solute-binding protein
JJN14_RS00575	COG1640	4-alpha-glucanotransferase
JJN14_RS00580	COG0058	SHG alpha-glucan phosphorylase activity
JJN14_RS00585	COG2226	methyltransferase
JJN14_RS00595	COG4499	WXG100 protein secretion system (Wss), protein YukC
JJN14_RS00595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JJN14_RS00600	COG1063	alcohol dehydrogenase
JJN14_RS00610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JJN14_RS00615	COG1459	type II secretion system
JJN14_RS00620	COG4537	Required for transformation and DNA binding
JJN14_RS00665	COG0706	membrane insertase activity
JJN14_RS00670	COG1847	R3H domain protein
JJN14_RS00680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JJN14_RS00690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JJN14_RS00700	COG1454	alcohol dehydrogenase
JJN14_RS00700	COG1012	belongs to the aldehyde dehydrogenase family
JJN14_RS00720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JJN14_RS00725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JJN14_RS00825	COG0697	spore germination
JJN14_RS00840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JJN14_RS00855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JJN14_RS00865	COG1132	(ABC) transporter
JJN14_RS00870	COG1132	(ABC) transporter
JJN14_RS00875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JJN14_RS00880	COG0166	Belongs to the GPI family
JJN14_RS00990	COG0534	Mate efflux family protein
JJN14_RS00995	COG0546	phosphoglycolate phosphatase activity
JJN14_RS01010	COG3759	membrane
JJN14_RS01015	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JJN14_RS01040	COG2176	DNA-directed DNA polymerase activity
JJN14_RS01050	COG2309	aminopeptidase activity
JJN14_RS01055	COG2261	transglycosylase associated protein
JJN14_RS01060	COG1187	pseudouridine synthase activity
JJN14_RS01065	COG3579	cysteine-type endopeptidase activity
JJN14_RS01070	COG3716	PTS system mannose fructose sorbose family IID component
JJN14_RS01075	COG3715	PTS system
JJN14_RS01085	COG1064	alcohol dehydrogenase
JJN14_RS01090	COG0561	phosphatase activity
JJN14_RS01095	COG2252	PERMEase
JJN14_RS01105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JJN14_RS01110	COG0285	dihydrofolate synthase activity
JJN14_RS01120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JJN14_RS01120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JJN14_RS01135	COG1609	Transcriptional regulator
JJN14_RS01140	COG0252	asparaginase activity
JJN14_RS01145	COG0561	phosphatase activity
JJN14_RS01150	COG0589	response to stress
JJN14_RS01160	COG0436	Aminotransferase
JJN14_RS01170	COG4166	transmembrane transport
JJN14_RS01175	COG0531	amino acid
JJN14_RS01215	COG0582	viral genome integration into host DNA
JJN14_RS01220	COG0084	hydrolase, TatD family'
JJN14_RS01235	COG1162	GTPase activity
JJN14_RS01245	COG1564	THIamine pyrophosphokinase
JJN14_RS01255	COG3481	metal-dependent phosphohydrolase, HD sub domain
JJN14_RS01260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JJN14_RS01270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JJN14_RS01280	COG1254	Belongs to the acylphosphatase family
JJN14_RS01285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JJN14_RS01300	COG0742	ribosomal rna small subunit methyltransferase
JJN14_RS01310	COG3480	Lon protease (S16) C-terminal proteolytic domain
JJN14_RS01320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JJN14_RS01335	COG1253	flavin adenine dinucleotide binding
JJN14_RS01345	COG4166	transmembrane transport
JJN14_RS01350	COG0601	transmembrane transport
JJN14_RS01355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JJN14_RS01360	COG0444	Belongs to the ABC transporter superfamily
JJN14_RS01365	COG4608	Belongs to the ABC transporter superfamily
JJN14_RS01370	COG0583	DNA-binding transcription factor activity
JJN14_RS01380	COG0281	malic enzyme
JJN14_RS01395	COG4120	Belongs to the binding-protein-dependent transport system permease family
JJN14_RS01400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JJN14_RS01405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JJN14_RS01410	COG0569	domain protein
JJN14_RS01425	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JJN14_RS01430	COG0671	phosphoesterase, PA-phosphatase related
JJN14_RS01440	COG1247	-acetyltransferase
JJN14_RS01450	COG0456	acetyltransferase
JJN14_RS01455	COG0072	phenylalanine-tRNA ligase activity
JJN14_RS01455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JJN14_RS01460	COG4152	abc transporter atp-binding protein
JJN14_RS01465	COG1668	transmembrane transport
JJN14_RS01470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JJN14_RS01475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JJN14_RS01765	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JJN14_RS01770	COG3620	sequence-specific DNA binding
JJN14_RS01775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JJN14_RS01795	COG3583	domain protein
JJN14_RS01795	COG3064	Membrane
JJN14_RS01795	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JJN14_RS01800	COG0386	Belongs to the glutathione peroxidase family
JJN14_RS01830	COG4839	cell division protein FtsL
JJN14_RS01835	COG0768	penicillin binding
JJN14_RS01890	COG0366	Alpha amylase catalytic
JJN14_RS01905	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JJN14_RS01915	COG0517	IMP dehydrogenase activity
JJN14_RS01935	COG1187	pseudouridine synthase activity
JJN14_RS01945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JJN14_RS01950	COG1363	Peptidase, m42
JJN14_RS01980	COG0789	Transcriptional regulator
JJN14_RS01985	COG0174	glutamine synthetase
JJN14_RS02010	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JJN14_RS02025	COG0484	heat shock protein binding
JJN14_RS02045	COG0537	adenosine 5'-monophosphoramidase activity
JJN14_RS02050	COG1131	(ABC) transporter
JJN14_RS02075	COG3290	protein histidine kinase activity
JJN14_RS02100	COG1266	CAAX protease self-immunity
JJN14_RS02120	COG0195	Participates in both transcription termination and antitermination
JJN14_RS02125	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JJN14_RS02175	COG0519	Catalyzes the synthesis of GMP from XMP
JJN14_RS02185	COG0525	valine-tRNA ligase activity
JJN14_RS02195	COG0326	Molecular chaperone. Has ATPase activity
JJN14_RS02210	COG0504	CTP synthase activity
JJN14_RS02225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JJN14_RS02230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JJN14_RS02235	COG4221	oxidoreductase activity
JJN14_RS02270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JJN14_RS02385	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JJN14_RS02385	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JJN14_RS02395	COG1846	Transcriptional regulator
JJN14_RS02405	COG0517	IMP dehydrogenase activity
JJN14_RS02405	COG1125	glycine betaine transport
JJN14_RS02410	COG1174	glycine betaine transport
JJN14_RS02420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JJN14_RS02430	COG1122	ATPase activity
JJN14_RS02440	COG1309	transcriptional regulator
JJN14_RS02445	COG1230	cation diffusion facilitator family transporter
JJN14_RS02450	COG1063	alcohol dehydrogenase
JJN14_RS02455	COG1609	Transcriptional regulator
JJN14_RS02460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JJN14_RS02475	COG2233	PERMEase
JJN14_RS02490	COG0708	Exodeoxyribonuclease III
JJN14_RS02505	COG1132	(ABC) transporter
JJN14_RS02510	COG1132	(ABC) transporter
JJN14_RS02515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JJN14_RS02520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JJN14_RS02525	COG0133	tryptophan synthase activity
JJN14_RS02530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JJN14_RS02535	COG0512	Glutamine amidotransferase of anthranilate synthase
JJN14_RS02550	COG0135	phosphoribosylanthranilate isomerase activity
JJN14_RS02580	COG3237	CsbD-like
JJN14_RS02605	COG3711	transcriptional antiterminator
JJN14_RS02610	COG0604	alcohol dehydrogenase
JJN14_RS02610	COG3321	synthase
JJN14_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
JJN14_RS02615	COG1959	2 iron, 2 sulfur cluster binding
JJN14_RS02625	COG0656	L-ascorbic acid biosynthetic process
JJN14_RS02640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JJN14_RS02650	COG1051	belongs to the nudix hydrolase family
JJN14_RS02655	COG2264	protein methyltransferase activity
JJN14_RS02660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JJN14_RS02665	COG1164	Oligoendopeptidase f
JJN14_RS02675	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JJN14_RS02690	COG0720	synthase
JJN14_RS02700	COG3118	belongs to the thioredoxin family
JJN14_RS02720	COG1346	cytolysis
JJN14_RS02730	COG1131	(ABC) transporter
JJN14_RS02735	COG1725	Transcriptional regulator
JJN14_RS02750	COG1484	DNA-dependent DNA replication
JJN14_RS02755	COG0778	Nitroreductase
JJN14_RS02775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JJN14_RS02780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JJN14_RS02795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JJN14_RS02800	COG3458	cephalosporin-C deacetylase activity
JJN14_RS02820	COG1175	transmembrane transport
JJN14_RS02825	COG0395	ABC-type sugar transport system, permease component
JJN14_RS02830	COG2731	YhcH YjgK YiaL family protein
JJN14_RS02840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JJN14_RS02865	COG0768	penicillin binding
JJN14_RS02935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JJN14_RS02940	COG1051	belongs to the nudix hydrolase family
JJN14_RS02960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JJN14_RS02980	COG3599	regulation of cell shape
JJN14_RS03005	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JJN14_RS03005	COG3583	domain protein
JJN14_RS03015	COG0577	efflux transmembrane transporter activity
JJN14_RS03015	COG1136	(ABC) transporter
JJN14_RS03105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JJN14_RS03125	COG0204	Acyl-transferase
JJN14_RS03130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JJN14_RS03135	COG2384	SAM-dependent methyltransferase
JJN14_RS03140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JJN14_RS03145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JJN14_RS03150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JJN14_RS03155	COG0463	Glycosyl transferase, family 2
JJN14_RS03175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JJN14_RS03195	COG0251	oxidation-reduction process
JJN14_RS03205	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JJN14_RS03215	COG0492	ferredoxin-NADP+ reductase activity
JJN14_RS03220	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JJN14_RS03240	COG1307	EDD domain protein, DegV family
JJN14_RS03250	COG0617	tRNA 3'-terminal CCA addition
JJN14_RS03255	COG0488	(ABC) transporter
JJN14_RS03265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JJN14_RS03275	COG0242	peptide deformylase activity
JJN14_RS03290	COG3711	transcriptional antiterminator
JJN14_RS03320	COG0436	Aminotransferase
JJN14_RS03330	COG0017	Asparaginyl-tRNA synthetase
JJN14_RS03340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JJN14_RS03345	COG3250	beta-galactosidase activity
JJN14_RS03360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JJN14_RS03370	COG1199	ATP-dependent helicase activity
JJN14_RS03370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JJN14_RS03375	COG0772	Belongs to the SEDS family
JJN14_RS03380	COG0693	protein deglycase activity
JJN14_RS03390	COG0629	single-stranded DNA binding
JJN14_RS03395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JJN14_RS03410	COG1098	S1 RNA binding domain
JJN14_RS03415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JJN14_RS03420	COG2827	Endonuclease containing a URI domain
JJN14_RS03445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JJN14_RS03450	COG2244	polysaccharide biosynthetic process
JJN14_RS03455	COG4166	transmembrane transport
JJN14_RS03460	COG0626	cystathionine gamma-synthase activity
JJN14_RS03465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JJN14_RS03470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JJN14_RS03495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JJN14_RS03505	COG1113	amino acid transport
JJN14_RS03515	COG1131	(ABC) transporter
JJN14_RS03535	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JJN14_RS03545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JJN14_RS03550	COG0785	Cytochrome C biogenesis protein
JJN14_RS03555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JJN14_RS03560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JJN14_RS03560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JJN14_RS03565	COG4753	response regulator
JJN14_RS03565	COG2207	Transcriptional regulator
JJN14_RS03570	COG2972	Histidine kinase
JJN14_RS03580	COG3064	Membrane
JJN14_RS03585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JJN14_RS03615	COG1940	carbohydrate kinase activity
JJN14_RS03630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JJN14_RS03635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JJN14_RS03640	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JJN14_RS03650	COG0300	oxidoreductase activity
JJN14_RS03655	COG3250	beta-galactosidase activity
JJN14_RS03665	COG1242	4 iron, 4 sulfur cluster binding
JJN14_RS03670	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JJN14_RS03710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JJN14_RS03735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JJN14_RS03745	COG0647	UMP catabolic process
JJN14_RS03755	COG1393	Belongs to the ArsC family
JJN14_RS03765	COG0483	inositol monophosphate 1-phosphatase activity
JJN14_RS03770	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JJN14_RS03770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JJN14_RS03775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JJN14_RS03780	COG0573	inorganic phosphate transmembrane transporter activity
JJN14_RS03785	COG0581	inorganic phosphate transmembrane transporter activity
JJN14_RS03790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JJN14_RS03795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JJN14_RS03800	COG0704	Plays a role in the regulation of phosphate uptake
JJN14_RS03805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JJN14_RS03810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JJN14_RS03815	COG3527	Alpha-acetolactate decarboxylase
JJN14_RS03830	COG3842	ATPase activity
JJN14_RS03850	COG1468	defense response to virus
JJN14_RS03850	COG1518	maintenance of DNA repeat elements
JJN14_RS03855	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JJN14_RS03875	COG1337	RAMP superfamily
JJN14_RS03880	COG1567	CRISPR-associated RAMP protein, Csm4 family
JJN14_RS03915	COG4555	ABC transporter
JJN14_RS03925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JJN14_RS03950	COG0287	Prephenate dehydrogenase
JJN14_RS03960	COG1704	LemA family
JJN14_RS03975	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JJN14_RS03980	COG0077	Prephenate dehydratase
JJN14_RS04055	COG3475	LICD family
JJN14_RS04060	COG1215	transferase activity, transferring glycosyl groups
JJN14_RS04065	COG3475	LICD family
JJN14_RS04070	COG3475	LICD family
JJN14_RS04100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JJN14_RS04100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JJN14_RS04105	COG1132	(ABC) transporter
JJN14_RS04115	COG0402	S-adenosylhomocysteine deaminase activity
JJN14_RS04120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JJN14_RS04160	COG1396	sequence-specific DNA binding
JJN14_RS04165	COG0542	response to heat
JJN14_RS04185	COG2130	NADP-dependent
JJN14_RS04190	COG1309	transcriptional regulator
JJN14_RS04195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JJN14_RS04200	COG0167	dihydroorotate dehydrogenase activity
JJN14_RS04215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JJN14_RS04220	COG4470	Protein conserved in bacteria
JJN14_RS04225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JJN14_RS04235	COG0488	(ABC) transporter
JJN14_RS04275	COG0697	spore germination
JJN14_RS04280	COG2267	carboxylic ester hydrolase activity
JJN14_RS04300	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JJN14_RS04300	COG1328	CTP reductase activity
JJN14_RS04310	COG4443	Transcriptional Coactivator p15 (PC4)
JJN14_RS04315	COG1268	BioY protein
JJN14_RS04320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JJN14_RS04325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JJN14_RS04330	COG1136	(ABC) transporter
JJN14_RS04335	COG0577	efflux transmembrane transporter activity
JJN14_RS04340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JJN14_RS04340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JJN14_RS04350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JJN14_RS04370	COG1136	(ABC) transporter
JJN14_RS04380	COG2188	Transcriptional regulator
JJN14_RS04385	COG0826	peptidase U32
JJN14_RS04395	COG0356	it plays a direct role in the translocation of protons across the membrane
JJN14_RS04430	COG0785	Cytochrome C biogenesis protein
JJN14_RS04435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JJN14_RS04440	COG1686	Belongs to the peptidase S11 family
JJN14_RS04445	COG0628	permease
JJN14_RS04455	COG2706	6-phosphogluconolactonase activity
JJN14_RS04460	COG0628	permease
JJN14_RS04475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JJN14_RS04480	COG3764	Sortase (surface protein transpeptidase)
JJN14_RS04510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JJN14_RS04535	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JJN14_RS04540	COG1438	arginine binding
JJN14_RS04545	COG0497	DNA recombination
JJN14_RS04550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JJN14_RS04580	COG3775	system Galactitol-specific IIC component
JJN14_RS04605	COG3684	Belongs to the aldolase LacD family
JJN14_RS04610	COG3711	transcriptional antiterminator
JJN14_RS04625	COG2723	6-phospho-beta-galactosidase activity
JJN14_RS04640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JJN14_RS04645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JJN14_RS04650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JJN14_RS04655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JJN14_RS04670	COG0803	Belongs to the bacterial solute-binding protein 9 family
JJN14_RS04670	COG3443	Belongs to the bacterial solute-binding protein 9 family
JJN14_RS04685	COG0803	Belongs to the bacterial solute-binding protein 9 family
JJN14_RS04685	COG3443	Belongs to the bacterial solute-binding protein 9 family
JJN14_RS04695	COG2195	Cleaves the N-terminal amino acid of tripeptides
JJN14_RS04705	COG1970	mechanosensitive ion channel activity
JJN14_RS04715	COG4708	membrane
JJN14_RS04725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JJN14_RS04735	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JJN14_RS04740	COG1942	4-Oxalocrotonate Tautomerase
JJN14_RS04745	COG1435	thymidine kinase activity
JJN14_RS04750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JJN14_RS04755	COG2890	protein-(glutamine-N5) methyltransferase activity
JJN14_RS04780	COG0741	lytic transglycosylase activity
JJN14_RS04790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JJN14_RS04815	COG1597	lipid kinase activity
JJN14_RS04835	COG1982	Orn Lys Arg decarboxylase major
JJN14_RS04840	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JJN14_RS04860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JJN14_RS04865	COG0745	RESPONSE REGULATOR receiver
JJN14_RS04870	COG2205	protein histidine kinase activity
JJN14_RS04880	COG1131	(ABC) transporter
JJN14_RS04885	COG0561	phosphatase activity
JJN14_RS04905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JJN14_RS04915	COG0038	chloride channel
JJN14_RS04950	COG0095	Lipoate-protein ligase
JJN14_RS04955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JJN14_RS04960	COG0508	dehydrogenase complex catalyzes the overall conversion of
JJN14_RS04965	COG0022	dehydrogenase e1 component
JJN14_RS04970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JJN14_RS04975	COG0534	Mate efflux family protein
JJN14_RS04980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JJN14_RS04985	COG1051	belongs to the nudix hydrolase family
JJN14_RS04995	COG1011	Hydrolase
JJN14_RS05050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JJN14_RS05060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JJN14_RS05065	COG1523	belongs to the glycosyl hydrolase 13 family
JJN14_RS05085	COG0488	(ABC) transporter
JJN14_RS05095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JJN14_RS05120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JJN14_RS05130	COG0745	RESPONSE REGULATOR receiver
JJN14_RS05135	COG1194	a g-specific adenine glycosylase
JJN14_RS05140	COG0280	phosphate acetyltransferase
JJN14_RS05145	COG0564	pseudouridine synthase activity
JJN14_RS05155	COG2357	RelA SpoT domain protein
JJN14_RS05165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JJN14_RS05170	COG1104	cysteine desulfurase activity
JJN14_RS05190	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JJN14_RS05200	COG0210	DNA helicase
JJN14_RS05210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JJN14_RS05215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JJN14_RS05220	COG4684	Psort location CytoplasmicMembrane, score
JJN14_RS05230	COG1827	regulation of RNA biosynthetic process
JJN14_RS05240	COG0556	nucleotide-excision repair
JJN14_RS05250	COG0765	amino acid transport
JJN14_RS05255	COG1126	abc transporter atp-binding protein
JJN14_RS05260	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JJN14_RS05265	COG0552	protein localization to endoplasmic reticulum
JJN14_RS05270	COG0561	phosphatase activity
JJN14_RS05275	COG0561	phosphatase activity
JJN14_RS05285	COG0577	efflux transmembrane transporter activity
JJN14_RS05290	COG1136	(ABC) transporter
JJN14_RS05300	COG2884	Cell division ATP-binding protein ftsE
JJN14_RS05315	COG2183	response to ionizing radiation
JJN14_RS05325	COG0701	Predicted permease
JJN14_RS05330	COG3689	TIGRFAM TIGR03943 family protein
JJN14_RS05335	COG0196	riboflavin kinase activity
JJN14_RS05340	COG1196	nuclear chromosome segregation
JJN14_RS05365	COG1401	restriction endodeoxyribonuclease activity
JJN14_RS05390	COG0473	3-isopropylmalate dehydrogenase activity
JJN14_RS05405	COG3142	Participates in the control of copper homeostasis
JJN14_RS05410	COG2832	Protein of unknown function (DUF454)
JJN14_RS05415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JJN14_RS05420	COG0758	DNA mediated transformation
JJN14_RS05425	COG4750	Nucleotidyl transferase
JJN14_RS05440	COG1063	alcohol dehydrogenase
JJN14_RS05450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JJN14_RS05455	COG0805	protein transport
JJN14_RS05460	COG0672	)-iron permease
JJN14_RS05465	COG2837	iron assimilation
JJN14_RS05470	COG2822	iron ion transport
JJN14_RS05480	COG0024	Methionine aminopeptidase
JJN14_RS05485	COG4109	DRTGG domain
JJN14_RS05495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JJN14_RS05500	COG0469	pyruvate kinase activity
JJN14_RS05515	COG2936	dipeptidyl-peptidase activity
JJN14_RS05520	COG1438	arginine binding
JJN14_RS05545	COG0438	transferase activity, transferring glycosyl groups
JJN14_RS05550	COG0438	transferase activity, transferring glycosyl groups
JJN14_RS05555	COG2151	metal-sulfur cluster biosynthetic enzyme
JJN14_RS05560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JJN14_RS05565	COG0358	DNA primase activity
JJN14_RS05585	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JJN14_RS05590	COG0772	Belongs to the SEDS family
JJN14_RS05600	COG4122	O-methyltransferase activity
JJN14_RS05625	COG0500	methyltransferase
JJN14_RS05625	COG3615	Tellurite resistance protein tehB
JJN14_RS05635	COG0557	exoribonuclease II activity
JJN14_RS05645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JJN14_RS05650	COG2814	Major facilitator Superfamily
JJN14_RS05655	COG0237	dephospho-CoA kinase activity
JJN14_RS05660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JJN14_RS05670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JJN14_RS05680	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JJN14_RS05685	COG0813	purine-nucleoside phosphorylase activity
JJN14_RS05695	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JJN14_RS05725	COG5002	protein histidine kinase activity
JJN14_RS05730	COG0745	RESPONSE REGULATOR receiver
JJN14_RS05745	COG1028	Short-chain dehydrogenase reductase Sdr
JJN14_RS05765	COG5263	repeat protein
JJN14_RS05765	COG4193	domain, Protein
JJN14_RS05770	COG0167	dihydroorotate dehydrogenase activity
JJN14_RS05775	COG0543	2 iron, 2 sulfur cluster binding
JJN14_RS05805	COG1131	(ABC) transporter
JJN14_RS05810	COG0658	competence protein
JJN14_RS05810	COG2333	competence protein COMEC
JJN14_RS05815	COG1555	photosystem II stabilization
JJN14_RS05815	COG1596	polysaccharide export
JJN14_RS05820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JJN14_RS05825	COG1702	phosphate starvation-inducible protein PhoH
JJN14_RS05835	COG2996	Protein conserved in bacteria
JJN14_RS05845	COG0528	UMP kinase activity
JJN14_RS05865	COG0470	DNA polymerase III
JJN14_RS05875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JJN14_RS05890	COG0564	pseudouridine synthase activity
JJN14_RS05895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JJN14_RS05900	COG0583	DNA-binding transcription factor activity
JJN14_RS05930	COG0513	Belongs to the DEAD box helicase family
JJN14_RS05935	COG0584	glycerophosphoryl diester phosphodiesterase
JJN14_RS05940	COG2176	DNA-directed DNA polymerase activity
JJN14_RS05950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JJN14_RS05960	COG0494	nUDIX hydrolase
JJN14_RS05965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JJN14_RS05980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JJN14_RS06000	COG1126	abc transporter atp-binding protein
JJN14_RS06025	COG1307	EDD domain protein, DegV family
JJN14_RS06030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JJN14_RS06035	COG0531	amino acid
JJN14_RS06040	COG0719	Fe-S assembly protein
JJN14_RS06050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JJN14_RS06055	COG0719	Fe-S assembly protein
JJN14_RS06070	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JJN14_RS06075	COG1956	GAF domain-containing protein
JJN14_RS06080	COG0539	negative regulation of cytoplasmic translation
JJN14_RS06100	COG4166	transmembrane transport
JJN14_RS06105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JJN14_RS06110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JJN14_RS06150	COG0187	DNA topoisomerase II activity
JJN14_RS06160	COG1079	Belongs to the binding-protein-dependent transport system permease family
JJN14_RS06165	COG4603	Belongs to the binding-protein-dependent transport system permease family
JJN14_RS06170	COG3845	ABC transporter
JJN14_RS06175	COG1744	ABC transporter substrate-binding protein PnrA-like
JJN14_RS06180	COG0295	cytidine deaminase activity
JJN14_RS06190	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JJN14_RS06195	COG2813	Specifically methylates the guanine in position
JJN14_RS06225	COG1078	dGTPase activity
JJN14_RS06390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JJN14_RS06395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JJN14_RS06400	COG1605	Chorismate mutase
JJN14_RS06400	COG0077	Prephenate dehydratase
JJN14_RS06405	COG0716	FMN binding
JJN14_RS06410	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JJN14_RS06455	COG0505	Belongs to the CarA family
JJN14_RS06470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JJN14_RS06485	COG0488	(ABC) transporter
JJN14_RS06495	COG1704	LemA family
JJN14_RS06515	COG0697	spore germination
JJN14_RS06520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JJN14_RS06530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JJN14_RS06555	COG1104	cysteine desulfurase activity
JJN14_RS06565	COG0697	spore germination
JJN14_RS06565	COG1674	ftsk spoiiie
JJN14_RS06570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JJN14_RS06570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JJN14_RS06570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JJN14_RS06575	COG1105	Belongs to the carbohydrate kinase PfkB family
JJN14_RS06580	COG1349	DNA-binding transcription factor activity
JJN14_RS06595	COG1914	H( )-stimulated, divalent metal cation uptake system
JJN14_RS06905	COG1396	sequence-specific DNA binding
JJN14_RS06925	COG0582	viral genome integration into host DNA
JJN14_RS06940	COG0561	phosphatase activity
JJN14_RS06960	COG0492	ferredoxin-NADP+ reductase activity
JJN14_RS06970	COG1126	abc transporter atp-binding protein
JJN14_RS06980	COG1393	Belongs to the ArsC family
JJN14_RS06985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JJN14_RS07000	COG1272	protein, Hemolysin III
JJN14_RS07030	COG3976	FMN-binding domain protein
JJN14_RS07030	COG1053	succinate dehydrogenase
JJN14_RS07030	COG0431	NADPH-dependent FMN reductase
JJN14_RS07060	COG0726	polysaccharide deacetylase
JJN14_RS07065	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JJN14_RS07070	COG0187	DNA topoisomerase II activity
JJN14_RS07080	COG1126	abc transporter atp-binding protein
JJN14_RS07085	COG0765	amino acid transport
JJN14_RS07090	COG4703	Protein of unknown function (DUF1797)
JJN14_RS07095	COG0542	response to heat
JJN14_RS07120	COG0513	Belongs to the DEAD box helicase family
JJN14_RS07130	COG1263	PTS System
JJN14_RS07130	COG2190	(PTS) system
JJN14_RS07130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJN14_RS07135	COG2177	Part of the ABC transporter FtsEX involved in
JJN14_RS07140	COG2884	Cell division ATP-binding protein ftsE
JJN14_RS07150	COG0517	IMP dehydrogenase activity
JJN14_RS07150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JJN14_RS07150	COG0617	tRNA 3'-terminal CCA addition
JJN14_RS07190	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JJN14_RS07195	COG2131	deaminase
JJN14_RS07205	COG1307	EDD domain protein, DegV family
JJN14_RS07210	COG2081	HI0933 family
JJN14_RS07220	COG0789	Transcriptional regulator
JJN14_RS07225	COG0733	neurotransmitter:sodium symporter activity
JJN14_RS07230	COG1482	cell wall glycoprotein biosynthetic process
JJN14_RS07285	COG0028	Belongs to the TPP enzyme family
JJN14_RS07290	COG2217	Heavy metal translocating P-type atpase
JJN14_RS07315	COG0352	thiamine-phosphate diphosphorylase activity
JJN14_RS07330	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JJN14_RS07340	COG4172	Belongs to the ABC transporter superfamily
JJN14_RS07350	COG0352	thiamine-phosphate diphosphorylase activity
JJN14_RS07355	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JJN14_RS07365	COG1304	FMN binding
JJN14_RS07380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JJN14_RS07400	COG1217	gtp-binding protein TYPA
JJN14_RS07405	COG1187	pseudouridine synthase activity
JJN14_RS07420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JJN14_RS07435	COG0860	N-Acetylmuramoyl-L-alanine amidase
JJN14_RS07450	COG1404	Belongs to the peptidase S8 family
JJN14_RS07530	COG4555	ABC transporter
JJN14_RS07540	COG2020	methyltransferase activity
JJN14_RS07545	COG0191	fructose-bisphosphate aldolase activity
JJN14_RS07550	COG5002	protein histidine kinase activity
JJN14_RS07555	COG0745	RESPONSE REGULATOR receiver
JJN14_RS07560	COG0577	efflux transmembrane transporter activity
JJN14_RS07565	COG1136	(ABC) transporter
JJN14_RS07570	COG0577	efflux transmembrane transporter activity
JJN14_RS07580	COG1335	isochorismatase
JJN14_RS07585	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JJN14_RS07595	COG0513	Belongs to the DEAD box helicase family
JJN14_RS07600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JJN14_RS07605	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JJN14_RS07610	COG3442	glutamine amidotransferase
JJN14_RS07615	COG0006	proline dipeptidase activity
JJN14_RS07620	COG4720	Psort location CytoplasmicMembrane, score
JJN14_RS07625	COG0351	phosphomethylpyrimidine kinase
JJN14_RS07645	COG2824	Alkylphosphonate utilization operon protein PhnA
JJN14_RS07665	COG3935	DnaD domain protein
JJN14_RS07680	COG2226	methyltransferase
JJN14_RS07705	COG1363	Peptidase, m42
JJN14_RS07710	COG1114	Component of the transport system for branched-chain amino acids
JJN14_RS07720	COG1573	uracil-dna glycosylase
JJN14_RS07725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JJN14_RS07760	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JJN14_RS07760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JJN14_RS07770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JJN14_RS07775	COG0765	amino acid transport
JJN14_RS07780	COG0765	amino acid transport
JJN14_RS07785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JJN14_RS07790	COG1959	2 iron, 2 sulfur cluster binding
JJN14_RS07810	COG5002	protein histidine kinase activity
JJN14_RS07815	COG0745	RESPONSE REGULATOR receiver
JJN14_RS07850	COG3590	peptidase
JJN14_RS07870	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JJN14_RS07910	COG3842	ATPase activity
JJN14_RS07920	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JJN14_RS07925	COG0215	cysteine-tRNA ligase activity
JJN14_RS07930	COG1045	serine acetyltransferase
JJN14_RS07945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JJN14_RS07950	COG3620	sequence-specific DNA binding
JJN14_RS07980	COG0732	type I restriction modification DNA specificity domain
JJN14_RS08005	COG1940	carbohydrate kinase activity
JJN14_RS08010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JJN14_RS08010	COG1263	PTS System
JJN14_RS08010	COG2190	(PTS) system
JJN14_RS08015	COG1621	beta-fructofuranosidase activity
JJN14_RS08020	COG1609	Transcriptional regulator
JJN14_RS08030	COG3425	synthase
JJN14_RS08045	COG2815	serine threonine protein kinase
JJN14_RS08045	COG0515	serine threonine protein kinase
JJN14_RS08050	COG0631	protein serine/threonine phosphatase activity
JJN14_RS08055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JJN14_RS08055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JJN14_RS08065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JJN14_RS08075	COG0194	GDP metabolic process
JJN14_RS08090	COG4115	mRNA cleavage
JJN14_RS08110	COG2226	methyltransferase
JJN14_RS08115	COG0799	negative regulation of ribosome biogenesis
JJN14_RS08120	COG1713	HD superfamily hydrolase involved in NAD metabolism
JJN14_RS08125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JJN14_RS08130	COG1534	Rna-binding protein
JJN14_RS08135	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JJN14_RS08150	COG0668	transmembrane transport
JJN14_RS08155	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JJN14_RS08175	COG0438	transferase activity, transferring glycosyl groups
JJN14_RS08180	COG0438	transferase activity, transferring glycosyl groups
JJN14_RS08185	COG0653	protein targeting
JJN14_RS08205	COG0201	protein transport
JJN14_RS08210	COG1442	glycosyl transferase family 8
JJN14_RS08215	COG1442	glycosyl transferase family 8
JJN14_RS08220	COG1442	glycosyl transferase family 8
JJN14_RS08220	COG1216	Glycosyl transferase, family 2
JJN14_RS08225	COG1442	glycosyl transferase family 8
JJN14_RS08230	COG0438	transferase activity, transferring glycosyl groups
JJN14_RS08235	COG1216	Glycosyl transferase, family 2
JJN14_RS08235	COG1442	glycosyl transferase family 8
JJN14_RS08240	COG1442	glycosyl transferase family 8
JJN14_RS08245	COG1442	glycosyl transferase family 8
JJN14_RS08245	COG1216	Glycosyl transferase, family 2
JJN14_RS08250	COG1442	glycosyl transferase family 8
JJN14_RS08250	COG1216	Glycosyl transferase, family 2
JJN14_RS08275	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JJN14_RS08295	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JJN14_RS08320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JJN14_RS08325	COG0439	Biotin carboxylase
JJN14_RS08340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JJN14_RS08345	COG1028	Short-chain dehydrogenase reductase Sdr
JJN14_RS08350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JJN14_RS08360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JJN14_RS08375	COG1024	Enoyl-CoA hydratase
JJN14_RS08380	COG0527	aspartate kinase activity
JJN14_RS08410	COG1115	amino acid carrier protein
JJN14_RS08435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JJN14_RS08445	COG0443	Heat shock 70 kDa protein
JJN14_RS08480	COG0681	Belongs to the peptidase S26 family
JJN14_RS08485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JJN14_RS08495	COG2197	response regulator
JJN14_RS08500	COG4585	Histidine kinase
JJN14_RS08540	COG0745	RESPONSE REGULATOR receiver
JJN14_RS08545	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JJN14_RS08555	COG0116	Belongs to the methyltransferase superfamily
JJN14_RS08580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JJN14_RS08590	COG0366	Alpha amylase catalytic
JJN14_RS08590	COG0366	Alpha amylase catalytic
JJN14_RS08590	COG0366	Alpha amylase catalytic
JJN14_RS08595	COG4166	transmembrane transport
JJN14_RS08600	COG0438	transferase activity, transferring glycosyl groups
JJN14_RS08605	COG0562	UDP-galactopyranose mutase
JJN14_RS08620	COG1216	Glycosyl transferase, family 2
JJN14_RS08620	COG1442	glycosyl transferase family 8
JJN14_RS08625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JJN14_RS08635	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JJN14_RS08640	COG3475	LICD family
JJN14_RS08650	COG0489	protein tyrosine kinase activity
JJN14_RS08655	COG3944	biosynthesis protein
JJN14_RS08660	COG4464	protein tyrosine phosphatase activity
JJN14_RS08670	COG4166	transmembrane transport
JJN14_RS08675	COG0366	Alpha amylase catalytic
JJN14_RS08695	COG1882	Formate acetyltransferase
JJN14_RS08700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JJN14_RS08715	COG0765	amino acid transport
JJN14_RS08730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JJN14_RS08740	COG0440	acetolactate synthase activity
JJN14_RS08745	COG0028	Belongs to the TPP enzyme family
JJN14_RS08765	COG2197	response regulator
JJN14_RS08770	COG4585	Histidine kinase
JJN14_RS08775	COG0842	Transport permease protein
JJN14_RS08780	COG1131	(ABC) transporter
JJN14_RS08795	COG1461	Dihydroxyacetone kinase
JJN14_RS08805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JJN14_RS08825	COG1132	(ABC) transporter
JJN14_RS08865	COG1316	TRANSCRIPTIONal
JJN14_RS08875	COG0802	atpase or kinase
JJN14_RS08900	COG1523	belongs to the glycosyl hydrolase 13 family
JJN14_RS08910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JJN14_RS08915	COG2723	6-phospho-beta-galactosidase activity
JJN14_RS08925	COG0750	zinc metalloprotease
JJN14_RS08930	COG4589	Belongs to the CDS family
JJN14_RS08935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JJN14_RS08945	COG2255	four-way junction helicase activity
JJN14_RS08975	COG2848	UPF0210 protein
JJN14_RS08980	COG3830	Belongs to the UPF0237 family
JJN14_RS08990	COG0202	RNA polymerase activity
JJN14_RS08995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JJN14_RS09005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JJN14_RS09010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JJN14_RS09020	COG0201	protein transport
JJN14_RS09035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JJN14_RS09055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JJN14_RS09075	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JJN14_RS09100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JJN14_RS09135	COG0602	queuosine metabolic process
JJN14_RS09160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JJN14_RS09170	COG0285	dihydrofolate synthase activity
JJN14_RS09195	COG1393	Belongs to the ArsC family
JJN14_RS09200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JJN14_RS09205	COG0006	proline dipeptidase activity
JJN14_RS09210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JJN14_RS09310	COG0582	viral genome integration into host DNA
JJN14_RS09340	COG2818	Glycosylase
JJN14_RS09370	COG1438	arginine binding
JJN14_RS09385	COG1780	Probably involved in ribonucleotide reductase function
JJN14_RS09395	COG4753	response regulator
JJN14_RS09395	COG2207	Transcriptional regulator
JJN14_RS09400	COG2972	Histidine kinase
JJN14_RS09435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JJN14_RS09440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JJN14_RS09445	COG1464	Belongs to the NlpA lipoprotein family
JJN14_RS09450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JJN14_RS09475	COG1214	PFAM Peptidase M22, glycoprotease
JJN14_RS09495	COG0445	tRNA wobble uridine modification
JJN14_RS09500	COG0494	nUDIX hydrolase
JJN14_RS09505	COG0494	nUDIX hydrolase
JJN14_RS09520	COG1388	LysM domain
JJN14_RS09520	COG1705	Flagellar rod assembly protein muramidase FlgJ
JJN14_RS09525	COG1760	l-serine dehydratase
JJN14_RS09530	COG1760	l-serine dehydratase
JJN14_RS09545	COG1216	Glycosyl transferase, family 2
JJN14_RS09555	COG1695	Transcriptional regulator
JJN14_RS09595	COG1653	transport
JJN14_RS09600	COG0395	ABC-type sugar transport system, permease component
JJN14_RS09605	COG4209	transmembrane transport
JJN14_RS09620	COG0383	alpha-mannosidase activity
JJN14_RS09630	COG3537	Alpha-1,2-mannosidase
JJN14_RS09640	COG0803	Belongs to the bacterial solute-binding protein 9 family
JJN14_RS09640	COG3443	Belongs to the bacterial solute-binding protein 9 family
JJN14_RS09645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JJN14_RS09650	COG1121	(ABC) transporter
JJN14_RS09655	COG1846	Transcriptional regulator
JJN14_RS09660	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JJN14_RS09670	COG1696	Membrane protein involved in D-alanine export
JJN14_RS09690	COG1696	Membrane protein involved in D-alanine export
JJN14_RS09695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JJN14_RS09700	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JJN14_RS09720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JJN14_RS09725	COG1335	isochorismatase
JJN14_RS09745	COG3201	nicotinamide mononucleotide transporter
JJN14_RS09750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JJN14_RS09755	COG0542	response to heat
JJN14_RS09760	COG4463	regulation of RNA biosynthetic process
JJN14_RS09765	COG1116	anion transmembrane transporter activity
JJN14_RS09770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JJN14_RS09775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JJN14_RS09785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JJN14_RS09785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JJN14_RS09810	COG0305	Participates in initiation and elongation during chromosome replication
JJN14_RS09830	COG1040	competence protein
JJN14_RS09835	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JJN14_RS09840	COG1739	Uncharacterized protein family UPF0029
JJN14_RS09865	COG2348	transferase activity, transferring amino-acyl groups
JJN14_RS09870	COG3942	CHAP domain
JJN14_RS09880	COG1792	Involved in formation and maintenance of cell shape
JJN14_RS09885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JJN14_RS09890	COG1122	ATPase activity
JJN14_RS09895	COG1122	ATPase activity
JJN14_RS09900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JJN14_RS09910	COG0612	Peptidase, M16
JJN14_RS09915	COG0612	Peptidase, M16
JJN14_RS09920	COG2501	S4 domain
JJN14_RS09930	COG0517	IMP dehydrogenase activity
JJN14_RS09930	COG0516	GMP reductase activity
JJN14_RS09935	COG0180	Tryptophanyl-tRNA synthetase
JJN14_RS09940	COG0488	(ABC) transporter
JJN14_RS09950	COG1511	domain protein
JJN14_RS09950	COG1511	domain protein
JJN14_RS09995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JJN14_RS10000	COG1475	DNA binding