locus-tag	class	description
SK637_RS00010	COG0592	DNA-directed DNA polymerase activity
SK637_RS00020	COG0012	GTP binding
SK637_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SK637_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SK637_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SK637_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SK637_RS00115	COG0756	dUTP diphosphatase activity
SK637_RS00140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SK637_RS00155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SK637_RS00205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SK637_RS00205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SK637_RS00210	COG1832	CoA-binding protein
SK637_RS00220	COG2855	membrane
SK637_RS00225	COG0436	Aminotransferase
SK637_RS00240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SK637_RS00305	COG2274	protein secretion by the type I secretion system
SK637_RS00310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SK637_RS00325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SK637_RS00330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SK637_RS00335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SK637_RS00340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SK637_RS00355	COG0138	bifunctional purine biosynthesis protein purh
SK637_RS00360	COG0151	Belongs to the GarS family
SK637_RS00370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SK637_RS00385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SK637_RS00400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SK637_RS00405	COG3715	PTS system
SK637_RS00410	COG3716	PTS system mannose fructose sorbose family IID component
SK637_RS00420	COG2222	sugar isomerase
SK637_RS00435	COG3583	domain protein
SK637_RS00470	COG2514	catechol 2,3-dioxygenase activity
SK637_RS00480	COG1301	dicarboxylic acid transport
SK637_RS00495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SK637_RS00500	COG0569	domain protein
SK637_RS00515	COG1215	transferase activity, transferring glycosyl groups
SK637_RS00530	COG5002	protein histidine kinase activity
SK637_RS00595	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SK637_RS00600	COG3177	Filamentation induced by cAMP protein fic
SK637_RS00620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SK637_RS00635	COG2151	metal-sulfur cluster biosynthetic enzyme
SK637_RS00665	COG1476	TRANSCRIPTIONal
SK637_RS00700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SK637_RS00705	COG1609	Transcriptional regulator
SK637_RS00710	COG5521	maltodextrose utilization protein MalA
SK637_RS00715	COG3833	ABC-type maltose transport systems, permease component
SK637_RS00720	COG1175	transmembrane transport
SK637_RS00725	COG2182	Extracellular solute-binding protein
SK637_RS00730	COG1640	4-alpha-glucanotransferase
SK637_RS00735	COG0058	SHG alpha-glucan phosphorylase activity
SK637_RS00745	COG2226	methyltransferase
SK637_RS00755	COG2217	Heavy metal translocating P-type atpase
SK637_RS00765	COG4499	WXG100 protein secretion system (Wss), protein YukC
SK637_RS00765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SK637_RS00770	COG0697	spore germination
SK637_RS00785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SK637_RS00795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SK637_RS00815	COG1438	arginine binding
SK637_RS00825	COG1132	(ABC) transporter
SK637_RS00830	COG1132	(ABC) transporter
SK637_RS00840	COG0166	Belongs to the GPI family
SK637_RS00950	COG0534	Mate efflux family protein
SK637_RS00970	COG3759	membrane
SK637_RS00975	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SK637_RS01000	COG1063	alcohol dehydrogenase
SK637_RS01010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SK637_RS01015	COG1459	type II secretion system
SK637_RS01020	COG4537	Required for transformation and DNA binding
SK637_RS01065	COG0706	membrane insertase activity
SK637_RS01070	COG1847	R3H domain protein
SK637_RS01085	COG3623	hexulose-6-phosphate isomerase
SK637_RS01095	COG1609	Transcriptional regulator
SK637_RS01110	COG3775	system Galactitol-specific IIC component
SK637_RS01120	COG1070	Carbohydrate kinase
SK637_RS01145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SK637_RS01150	COG1862	Preprotein translocase
SK637_RS01155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SK637_RS01165	COG1012	belongs to the aldehyde dehydrogenase family
SK637_RS01165	COG1454	alcohol dehydrogenase
SK637_RS01180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SK637_RS01185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SK637_RS01290	COG1131	(ABC) transporter
SK637_RS01295	COG0842	Transport permease protein
SK637_RS01300	COG4585	Histidine kinase
SK637_RS01305	COG2197	response regulator
SK637_RS01335	COG2176	DNA-directed DNA polymerase activity
SK637_RS01345	COG3041	Addiction module toxin RelE StbE family
SK637_RS01355	COG2309	aminopeptidase activity
SK637_RS01360	COG2261	transglycosylase associated protein
SK637_RS01370	COG1187	pseudouridine synthase activity
SK637_RS01375	COG3579	cysteine-type endopeptidase activity
SK637_RS01400	COG3716	PTS system mannose fructose sorbose family IID component
SK637_RS01405	COG3715	PTS system
SK637_RS01415	COG1064	alcohol dehydrogenase
SK637_RS01420	COG0561	phosphatase activity
SK637_RS01425	COG2252	PERMEase
SK637_RS01435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SK637_RS01440	COG0285	dihydrofolate synthase activity
SK637_RS01450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SK637_RS01450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SK637_RS01460	COG1609	Transcriptional regulator
SK637_RS01465	COG0252	asparaginase activity
SK637_RS01470	COG0561	phosphatase activity
SK637_RS01475	COG0589	response to stress
SK637_RS01485	COG0436	Aminotransferase
SK637_RS01495	COG4166	transmembrane transport
SK637_RS01500	COG0531	amino acid
SK637_RS01510	COG0084	hydrolase, TatD family'
SK637_RS01530	COG1162	GTPase activity
SK637_RS01540	COG1564	THIamine pyrophosphokinase
SK637_RS01550	COG3481	metal-dependent phosphohydrolase, HD sub domain
SK637_RS01555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SK637_RS01565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SK637_RS01575	COG1254	Belongs to the acylphosphatase family
SK637_RS01580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SK637_RS01600	COG0742	ribosomal rna small subunit methyltransferase
SK637_RS01610	COG3480	Lon protease (S16) C-terminal proteolytic domain
SK637_RS01620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SK637_RS01635	COG1253	flavin adenine dinucleotide binding
SK637_RS01655	COG4166	transmembrane transport
SK637_RS01660	COG0601	transmembrane transport
SK637_RS01665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SK637_RS01670	COG0444	Belongs to the ABC transporter superfamily
SK637_RS01675	COG4608	Belongs to the ABC transporter superfamily
SK637_RS01685	COG4120	Belongs to the binding-protein-dependent transport system permease family
SK637_RS01690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SK637_RS01695	COG2188	Transcriptional regulator
SK637_RS01700	COG1263	PTS System
SK637_RS01700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SK637_RS01705	COG0366	Alpha amylase catalytic
SK637_RS01720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SK637_RS01750	COG1187	pseudouridine synthase activity
SK637_RS01770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SK637_RS01780	COG1363	Peptidase, m42
SK637_RS01810	COG0789	Transcriptional regulator
SK637_RS01815	COG0174	glutamine synthetase
SK637_RS01825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SK637_RS01840	COG0484	heat shock protein binding
SK637_RS01855	COG0537	adenosine 5'-monophosphoramidase activity
SK637_RS01860	COG1131	(ABC) transporter
SK637_RS01880	COG3290	protein histidine kinase activity
SK637_RS01915	COG1266	CAAX protease self-immunity
SK637_RS01935	COG0195	Participates in both transcription termination and antitermination
SK637_RS01940	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SK637_RS01990	COG0519	Catalyzes the synthesis of GMP from XMP
SK637_RS02000	COG0525	valine-tRNA ligase activity
SK637_RS02015	COG0504	CTP synthase activity
SK637_RS02030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SK637_RS02035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SK637_RS02040	COG4221	oxidoreductase activity
SK637_RS02075	COG0582	viral genome integration into host DNA
SK637_RS02085	COG3177	Filamentation induced by cAMP protein fic
SK637_RS02180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SK637_RS02295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SK637_RS02295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SK637_RS02305	COG1846	Transcriptional regulator
SK637_RS02315	COG1125	glycine betaine transport
SK637_RS02315	COG0517	IMP dehydrogenase activity
SK637_RS02320	COG1174	glycine betaine transport
SK637_RS02330	COG1230	cation diffusion facilitator family transporter
SK637_RS02335	COG1609	Transcriptional regulator
SK637_RS02340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SK637_RS02345	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SK637_RS02355	COG2233	PERMEase
SK637_RS02375	COG0708	Exodeoxyribonuclease III
SK637_RS02385	COG0640	Transcriptional regulator
SK637_RS02405	COG1132	(ABC) transporter
SK637_RS02410	COG1132	(ABC) transporter
SK637_RS02415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SK637_RS02425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SK637_RS02430	COG0512	Glutamine amidotransferase of anthranilate synthase
SK637_RS02445	COG0135	phosphoribosylanthranilate isomerase activity
SK637_RS02460	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SK637_RS02475	COG3237	CsbD-like
SK637_RS02495	COG2261	transglycosylase associated protein
SK637_RS02500	COG3711	transcriptional antiterminator
SK637_RS02525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SK637_RS02535	COG1051	belongs to the nudix hydrolase family
SK637_RS02540	COG2264	protein methyltransferase activity
SK637_RS02545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SK637_RS02550	COG1164	Oligoendopeptidase f
SK637_RS02565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SK637_RS02575	COG0720	synthase
SK637_RS02585	COG3118	belongs to the thioredoxin family
SK637_RS02605	COG1346	cytolysis
SK637_RS02620	COG1131	(ABC) transporter
SK637_RS02625	COG1725	Transcriptional regulator
SK637_RS02640	COG1484	DNA-dependent DNA replication
SK637_RS02645	COG0778	Nitroreductase
SK637_RS02675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SK637_RS02680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SK637_RS02695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SK637_RS02720	COG3458	cephalosporin-C deacetylase activity
SK637_RS02735	COG1175	transmembrane transport
SK637_RS02740	COG0395	ABC-type sugar transport system, permease component
SK637_RS02745	COG2731	YhcH YjgK YiaL family protein
SK637_RS02755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SK637_RS02780	COG0768	penicillin binding
SK637_RS02795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SK637_RS02815	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SK637_RS02835	COG3599	regulation of cell shape
SK637_RS02855	COG0577	efflux transmembrane transporter activity
SK637_RS02855	COG1136	(ABC) transporter
SK637_RS02870	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SK637_RS02890	COG3590	peptidase
SK637_RS02900	COG0860	N-Acetylmuramoyl-L-alanine amidase
SK637_RS02900	COG2247	cell wall binding repeat
SK637_RS02910	COG1716	ATPase activity
SK637_RS02910	COG0842	Transport permease protein
SK637_RS02910	COG1131	(ABC) transporter
SK637_RS02960	COG1959	2 iron, 2 sulfur cluster binding
SK637_RS02980	COG0745	RESPONSE REGULATOR receiver
SK637_RS02985	COG5002	protein histidine kinase activity
SK637_RS02990	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SK637_RS03030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SK637_RS03050	COG0204	Acyl-transferase
SK637_RS03055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SK637_RS03060	COG2384	SAM-dependent methyltransferase
SK637_RS03065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SK637_RS03070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SK637_RS03075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SK637_RS03080	COG0463	Glycosyl transferase, family 2
SK637_RS03100	COG2824	Alkylphosphonate utilization operon protein PhnA
SK637_RS03120	COG0351	phosphomethylpyrimidine kinase
SK637_RS03125	COG4720	Psort location CytoplasmicMembrane, score
SK637_RS03135	COG0006	proline dipeptidase activity
SK637_RS03140	COG3442	glutamine amidotransferase
SK637_RS03145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SK637_RS03150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SK637_RS03155	COG0513	Belongs to the DEAD box helicase family
SK637_RS03165	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SK637_RS03170	COG1335	isochorismatase
SK637_RS03190	COG0577	efflux transmembrane transporter activity
SK637_RS03195	COG1136	(ABC) transporter
SK637_RS03200	COG0577	efflux transmembrane transporter activity
SK637_RS03205	COG0745	RESPONSE REGULATOR receiver
SK637_RS03210	COG5002	protein histidine kinase activity
SK637_RS03215	COG0191	fructose-bisphosphate aldolase activity
SK637_RS03220	COG2020	methyltransferase activity
SK637_RS03225	COG4555	ABC transporter
SK637_RS03255	COG1242	4 iron, 4 sulfur cluster binding
SK637_RS03260	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SK637_RS03300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SK637_RS03305	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SK637_RS03325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SK637_RS03335	COG0647	UMP catabolic process
SK637_RS03365	COG1393	Belongs to the ArsC family
SK637_RS03375	COG0483	inositol monophosphate 1-phosphatase activity
SK637_RS03380	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SK637_RS03380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SK637_RS03385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SK637_RS03390	COG0573	inorganic phosphate transmembrane transporter activity
SK637_RS03395	COG0581	inorganic phosphate transmembrane transporter activity
SK637_RS03400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SK637_RS03405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SK637_RS03410	COG0704	Plays a role in the regulation of phosphate uptake
SK637_RS03420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SK637_RS03425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SK637_RS03430	COG3527	Alpha-acetolactate decarboxylase
SK637_RS03445	COG3842	ATPase activity
SK637_RS03485	COG4555	ABC transporter
SK637_RS03505	COG1368	sulfuric ester hydrolase activity
SK637_RS03510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SK637_RS03535	COG0287	Prephenate dehydrogenase
SK637_RS03545	COG1704	LemA family
SK637_RS03560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SK637_RS03565	COG0077	Prephenate dehydratase
SK637_RS03575	COG3475	LICD family
SK637_RS03585	COG1215	transferase activity, transferring glycosyl groups
SK637_RS03620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SK637_RS03620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SK637_RS03635	COG0402	S-adenosylhomocysteine deaminase activity
SK637_RS03645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SK637_RS03655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SK637_RS03660	COG0167	dihydroorotate dehydrogenase activity
SK637_RS03675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SK637_RS03680	COG4470	Protein conserved in bacteria
SK637_RS03685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SK637_RS03695	COG0488	(ABC) transporter
SK637_RS03755	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SK637_RS03755	COG1328	CTP reductase activity
SK637_RS03765	COG4443	Transcriptional Coactivator p15 (PC4)
SK637_RS03775	COG1268	BioY protein
SK637_RS03780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SK637_RS03785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SK637_RS03790	COG1136	(ABC) transporter
SK637_RS03795	COG0577	efflux transmembrane transporter activity
SK637_RS03800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SK637_RS03800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SK637_RS03805	COG4989	oxidoreductase activity
SK637_RS03815	COG1028	Short-chain dehydrogenase reductase Sdr
SK637_RS03840	COG0745	RESPONSE REGULATOR receiver
SK637_RS03845	COG5002	protein histidine kinase activity
SK637_RS03860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SK637_RS03860	COG1199	ATP-dependent helicase activity
SK637_RS03865	COG0772	Belongs to the SEDS family
SK637_RS03870	COG0693	protein deglycase activity
SK637_RS03880	COG0187	DNA topoisomerase II activity
SK637_RS03885	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SK637_RS03905	COG0542	response to heat
SK637_RS03910	COG4703	Protein of unknown function (DUF1797)
SK637_RS03915	COG0765	amino acid transport
SK637_RS03920	COG1126	abc transporter atp-binding protein
SK637_RS03925	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SK637_RS03935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SK637_RS03960	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SK637_RS03975	COG0813	purine-nucleoside phosphorylase activity
SK637_RS04005	COG2813	Specifically methylates the guanine in position
SK637_RS04010	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SK637_RS04025	COG1744	ABC transporter substrate-binding protein PnrA-like
SK637_RS04030	COG3845	ABC transporter
SK637_RS04035	COG4603	Belongs to the binding-protein-dependent transport system permease family
SK637_RS04040	COG1079	Belongs to the binding-protein-dependent transport system permease family
SK637_RS04050	COG0187	DNA topoisomerase II activity
SK637_RS04085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SK637_RS04090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SK637_RS04095	COG4166	transmembrane transport
SK637_RS04115	COG0539	negative regulation of cytoplasmic translation
SK637_RS04120	COG1956	GAF domain-containing protein
SK637_RS04125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SK637_RS04140	COG0719	Fe-S assembly protein
SK637_RS04145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SK637_RS04155	COG0719	Fe-S assembly protein
SK637_RS04160	COG1686	Belongs to the peptidase S11 family
SK637_RS04165	COG0628	permease
SK637_RS04205	COG0583	DNA-binding transcription factor activity
SK637_RS04210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SK637_RS04215	COG0564	pseudouridine synthase activity
SK637_RS04220	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SK637_RS04235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SK637_RS04265	COG0528	UMP kinase activity
SK637_RS04275	COG2996	Protein conserved in bacteria
SK637_RS04285	COG1702	phosphate starvation-inducible protein PhoH
SK637_RS04290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SK637_RS04295	COG1555	photosystem II stabilization
SK637_RS04295	COG1596	polysaccharide export
SK637_RS04300	COG2333	competence protein COMEC
SK637_RS04300	COG0658	competence protein
SK637_RS04310	COG1131	(ABC) transporter
SK637_RS04340	COG0543	2 iron, 2 sulfur cluster binding
SK637_RS04345	COG0167	dihydroorotate dehydrogenase activity
SK637_RS04350	COG5263	repeat protein
SK637_RS04350	COG4193	domain, Protein
SK637_RS04355	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SK637_RS04365	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SK637_RS04375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SK637_RS04380	COG2814	Major facilitator Superfamily
SK637_RS04385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SK637_RS04395	COG0557	exoribonuclease II activity
SK637_RS04405	COG3615	Tellurite resistance protein tehB
SK637_RS04405	COG0500	methyltransferase
SK637_RS04410	COG1724	mRNA binding
SK637_RS04430	COG4122	O-methyltransferase activity
SK637_RS04440	COG0772	Belongs to the SEDS family
SK637_RS04445	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SK637_RS04465	COG0358	DNA primase activity
SK637_RS04470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SK637_RS04475	COG2151	metal-sulfur cluster biosynthetic enzyme
SK637_RS04480	COG0438	transferase activity, transferring glycosyl groups
SK637_RS04485	COG0438	transferase activity, transferring glycosyl groups
SK637_RS04510	COG1438	arginine binding
SK637_RS04535	COG0469	pyruvate kinase activity
SK637_RS04545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SK637_RS04550	COG3764	Sortase (surface protein transpeptidase)
SK637_RS04585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SK637_RS04610	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SK637_RS04615	COG1438	arginine binding
SK637_RS04620	COG0497	DNA recombination
SK637_RS04625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SK637_RS04645	COG3775	system Galactitol-specific IIC component
SK637_RS04670	COG3684	Belongs to the aldolase LacD family
SK637_RS04675	COG3711	transcriptional antiterminator
SK637_RS04705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SK637_RS04710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SK637_RS04715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SK637_RS04720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SK637_RS04740	COG2376	Dihydroxyacetone kinase
SK637_RS04750	COG2376	Dihydroxyacetone kinase
SK637_RS04755	COG1461	Dihydroxyacetone kinase
SK637_RS04760	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SK637_RS04785	COG1011	Hydrolase
SK637_RS04795	COG1051	belongs to the nudix hydrolase family
SK637_RS04800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SK637_RS04805	COG0534	Mate efflux family protein
SK637_RS04820	COG0038	chloride channel
SK637_RS04830	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SK637_RS04865	COG0561	phosphatase activity
SK637_RS04870	COG1131	(ABC) transporter
SK637_RS04880	COG2205	protein histidine kinase activity
SK637_RS04885	COG0745	RESPONSE REGULATOR receiver
SK637_RS04890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SK637_RS04910	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SK637_RS04915	COG1982	Orn Lys Arg decarboxylase major
SK637_RS04925	COG0577	efflux transmembrane transporter activity
SK637_RS04930	COG1136	(ABC) transporter
SK637_RS04950	COG2183	response to ionizing radiation
SK637_RS04965	COG0701	Predicted permease
SK637_RS04970	COG3689	TIGRFAM TIGR03943 family protein
SK637_RS04990	COG0210	DNA helicase
SK637_RS05035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SK637_RS05060	COG0542	response to heat
SK637_RS05065	COG1396	sequence-specific DNA binding
SK637_RS05075	COG0366	Alpha amylase catalytic
SK637_RS05080	COG0135	phosphoribosylanthranilate isomerase activity
SK637_RS05085	COG1597	lipid kinase activity
SK637_RS05125	COG0488	(ABC) transporter
SK637_RS05140	COG2217	Heavy metal translocating P-type atpase
SK637_RS05145	COG0640	Transcriptional regulator
SK637_RS05160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SK637_RS05170	COG0741	lytic transglycosylase activity
SK637_RS05195	COG2890	protein-(glutamine-N5) methyltransferase activity
SK637_RS05210	COG1435	thymidine kinase activity
SK637_RS05215	COG1942	4-Oxalocrotonate Tautomerase
SK637_RS05220	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SK637_RS05230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SK637_RS05240	COG4708	membrane
SK637_RS05250	COG1970	mechanosensitive ion channel activity
SK637_RS05260	COG2195	Cleaves the N-terminal amino acid of tripeptides
SK637_RS05275	COG3443	Belongs to the bacterial solute-binding protein 9 family
SK637_RS05275	COG0803	Belongs to the bacterial solute-binding protein 9 family
SK637_RS05280	COG0531	amino acid
SK637_RS05285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SK637_RS05290	COG0785	Cytochrome C biogenesis protein
SK637_RS05300	COG1307	EDD domain protein, DegV family
SK637_RS05305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SK637_RS05310	COG0196	riboflavin kinase activity
SK637_RS05315	COG0024	Methionine aminopeptidase
SK637_RS05320	COG4109	DRTGG domain
SK637_RS05330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SK637_RS05350	COG0560	Phosphoserine phosphatase
SK637_RS05360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SK637_RS05370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SK637_RS05375	COG1523	belongs to the glycosyl hydrolase 13 family
SK637_RS05395	COG0488	(ABC) transporter
SK637_RS05400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SK637_RS05410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SK637_RS05415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SK637_RS05425	COG0745	RESPONSE REGULATOR receiver
SK637_RS05430	COG1194	a g-specific adenine glycosylase
SK637_RS05435	COG0280	phosphate acetyltransferase
SK637_RS05440	COG0564	pseudouridine synthase activity
SK637_RS05450	COG2357	RelA SpoT domain protein
SK637_RS05460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SK637_RS05465	COG1104	cysteine desulfurase activity
SK637_RS05485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SK637_RS05495	COG0210	DNA helicase
SK637_RS05510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SK637_RS05515	COG4684	Psort location CytoplasmicMembrane, score
SK637_RS05525	COG1827	regulation of RNA biosynthetic process
SK637_RS05530	COG1051	belongs to the nudix hydrolase family
SK637_RS05545	COG0556	nucleotide-excision repair
SK637_RS05555	COG0765	amino acid transport
SK637_RS05560	COG1126	abc transporter atp-binding protein
SK637_RS05565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SK637_RS05570	COG0552	protein localization to endoplasmic reticulum
SK637_RS05575	COG0561	phosphatase activity
SK637_RS05580	COG0561	phosphatase activity
SK637_RS05585	COG1196	nuclear chromosome segregation
SK637_RS05610	COG1401	restriction endodeoxyribonuclease activity
SK637_RS05635	COG0473	3-isopropylmalate dehydrogenase activity
SK637_RS05650	COG3142	Participates in the control of copper homeostasis
SK637_RS05655	COG2832	Protein of unknown function (DUF454)
SK637_RS05660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SK637_RS05665	COG0758	DNA mediated transformation
SK637_RS05670	COG4750	Nucleotidyl transferase
SK637_RS05685	COG1063	alcohol dehydrogenase
SK637_RS05705	COG3475	LICD family
SK637_RS05710	COG3475	LICD family
SK637_RS05720	COG0505	Belongs to the CarA family
SK637_RS05735	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SK637_RS05750	COG0488	(ABC) transporter
SK637_RS05760	COG1704	LemA family
SK637_RS05780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SK637_RS05795	COG1078	dGTPase activity
SK637_RS05850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SK637_RS05855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SK637_RS05865	COG0716	FMN binding
SK637_RS05870	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SK637_RS05880	COG1914	H( )-stimulated, divalent metal cation uptake system
SK637_RS05885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SK637_RS05890	COG0805	protein transport
SK637_RS05895	COG0672	)-iron permease
SK637_RS05900	COG2837	iron assimilation
SK637_RS05905	COG2822	iron ion transport
SK637_RS05945	COG0584	glycerophosphoryl diester phosphodiesterase
SK637_RS05950	COG2176	DNA-directed DNA polymerase activity
SK637_RS05960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SK637_RS05970	COG0494	nUDIX hydrolase
SK637_RS05975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SK637_RS05990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SK637_RS06015	COG1126	abc transporter atp-binding protein
SK637_RS06030	COG0628	permease
SK637_RS06035	COG4166	transmembrane transport
SK637_RS06040	COG2706	6-phosphogluconolactonase activity
SK637_RS06085	COG0826	peptidase U32
SK637_RS06090	COG3064	Membrane
SK637_RS06100	COG2188	Transcriptional regulator
SK637_RS06105	COG0697	spore germination
SK637_RS06110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SK637_RS06155	COG1104	cysteine desulfurase activity
SK637_RS06165	COG0697	spore germination
SK637_RS06165	COG1674	ftsk spoiiie
SK637_RS06170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SK637_RS06170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SK637_RS06170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SK637_RS06175	COG1105	Belongs to the carbohydrate kinase PfkB family
SK637_RS06180	COG1349	DNA-binding transcription factor activity
SK637_RS06240	COG0561	phosphatase activity
SK637_RS06265	COG0492	ferredoxin-NADP+ reductase activity
SK637_RS06275	COG1126	abc transporter atp-binding protein
SK637_RS06285	COG1393	Belongs to the ArsC family
SK637_RS06290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SK637_RS06305	COG1272	protein, Hemolysin III
SK637_RS06335	COG3976	FMN-binding domain protein
SK637_RS06335	COG1053	succinate dehydrogenase
SK637_RS06335	COG0431	NADPH-dependent FMN reductase
SK637_RS06360	COG0656	L-ascorbic acid biosynthetic process
SK637_RS06365	COG0726	polysaccharide deacetylase
SK637_RS06380	COG0513	Belongs to the DEAD box helicase family
SK637_RS06390	COG1263	PTS System
SK637_RS06390	COG2190	(PTS) system
SK637_RS06390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SK637_RS06395	COG2177	Part of the ABC transporter FtsEX involved in
SK637_RS06400	COG2884	Cell division ATP-binding protein ftsE
SK637_RS06415	COG0517	IMP dehydrogenase activity
SK637_RS06415	COG0617	tRNA 3'-terminal CCA addition
SK637_RS06415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SK637_RS06465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SK637_RS06470	COG2131	deaminase
SK637_RS06480	COG1307	EDD domain protein, DegV family
SK637_RS06485	COG2081	HI0933 family
SK637_RS06495	COG0789	Transcriptional regulator
SK637_RS06505	COG0733	neurotransmitter:sodium symporter activity
SK637_RS06510	COG1482	cell wall glycoprotein biosynthetic process
SK637_RS06520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SK637_RS06530	COG0028	Belongs to the TPP enzyme family
SK637_RS06535	COG2217	Heavy metal translocating P-type atpase
SK637_RS06555	COG0352	thiamine-phosphate diphosphorylase activity
SK637_RS06570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SK637_RS06580	COG4172	Belongs to the ABC transporter superfamily
SK637_RS06590	COG0352	thiamine-phosphate diphosphorylase activity
SK637_RS06595	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SK637_RS06605	COG1304	FMN binding
SK637_RS06620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SK637_RS06640	COG1136	(ABC) transporter
SK637_RS06655	COG1217	gtp-binding protein TYPA
SK637_RS06660	COG1187	pseudouridine synthase activity
SK637_RS06665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SK637_RS06675	COG2197	response regulator
SK637_RS06690	COG1136	(ABC) transporter
SK637_RS06735	COG5263	repeat protein
SK637_RS06735	COG4193	domain, Protein
SK637_RS06755	COG0300	oxidoreductase activity
SK637_RS06765	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SK637_RS06770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SK637_RS06775	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SK637_RS06790	COG1940	carbohydrate kinase activity
SK637_RS06805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SK637_RS06810	COG3064	Membrane
SK637_RS06820	COG2972	Histidine kinase
SK637_RS06825	COG4753	response regulator
SK637_RS06825	COG2207	Transcriptional regulator
SK637_RS06830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SK637_RS06830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SK637_RS06835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SK637_RS06840	COG0785	Cytochrome C biogenesis protein
SK637_RS06845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SK637_RS06855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SK637_RS06880	COG1113	amino acid transport
SK637_RS06915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SK637_RS06925	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SK637_RS06930	COG0626	cystathionine gamma-synthase activity
SK637_RS06940	COG4166	transmembrane transport
SK637_RS06945	COG2244	polysaccharide biosynthetic process
SK637_RS06950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SK637_RS06980	COG2827	Endonuclease containing a URI domain
SK637_RS06985	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SK637_RS06990	COG1098	S1 RNA binding domain
SK637_RS07000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SK637_RS07005	COG0629	single-stranded DNA binding
SK637_RS07030	COG0436	Aminotransferase
SK637_RS07055	COG3711	transcriptional antiterminator
SK637_RS07080	COG0242	peptide deformylase activity
SK637_RS07095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SK637_RS07100	COG0488	(ABC) transporter
SK637_RS07105	COG0617	tRNA 3'-terminal CCA addition
SK637_RS07115	COG1307	EDD domain protein, DegV family
SK637_RS07135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SK637_RS07140	COG0492	ferredoxin-NADP+ reductase activity
SK637_RS07155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SK637_RS07165	COG0251	oxidation-reduction process
SK637_RS07185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SK637_RS07195	COG4193	domain, Protein
SK637_RS07195	COG5263	repeat protein
SK637_RS07205	COG3935	DnaD domain protein
SK637_RS07260	COG1363	Peptidase, m42
SK637_RS07265	COG1114	Component of the transport system for branched-chain amino acids
SK637_RS07275	COG1573	uracil-dna glycosylase
SK637_RS07290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SK637_RS07320	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SK637_RS07320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SK637_RS07330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SK637_RS07335	COG0765	amino acid transport
SK637_RS07340	COG0765	amino acid transport
SK637_RS07345	COG3842	ATPase activity
SK637_RS07355	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SK637_RS07360	COG0215	cysteine-tRNA ligase activity
SK637_RS07375	COG1045	serine acetyltransferase
SK637_RS07410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SK637_RS07480	COG1940	carbohydrate kinase activity
SK637_RS07485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SK637_RS07485	COG2190	(PTS) system
SK637_RS07485	COG1263	PTS System
SK637_RS07500	COG1621	beta-fructofuranosidase activity
SK637_RS07505	COG1609	Transcriptional regulator
SK637_RS07515	COG3425	synthase
SK637_RS07530	COG2815	serine threonine protein kinase
SK637_RS07530	COG0515	serine threonine protein kinase
SK637_RS07535	COG0631	protein serine/threonine phosphatase activity
SK637_RS07550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SK637_RS07560	COG0194	GDP metabolic process
SK637_RS07575	COG4115	mRNA cleavage
SK637_RS07590	COG2226	methyltransferase
SK637_RS07595	COG0799	negative regulation of ribosome biogenesis
SK637_RS07605	COG1713	HD superfamily hydrolase involved in NAD metabolism
SK637_RS07610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SK637_RS07615	COG1534	Rna-binding protein
SK637_RS07620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SK637_RS07635	COG0668	transmembrane transport
SK637_RS07640	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
SK637_RS07660	COG0438	transferase activity, transferring glycosyl groups
SK637_RS07665	COG0438	transferase activity, transferring glycosyl groups
SK637_RS07670	COG0653	protein targeting
SK637_RS07690	COG0201	protein transport
SK637_RS07695	COG1215	transferase activity, transferring glycosyl groups
SK637_RS07700	COG1442	glycosyl transferase family 8
SK637_RS07705	COG1442	glycosyl transferase family 8
SK637_RS07710	COG1442	glycosyl transferase family 8
SK637_RS07710	COG1216	Glycosyl transferase, family 2
SK637_RS07715	COG1442	glycosyl transferase family 8
SK637_RS07720	COG0438	transferase activity, transferring glycosyl groups
SK637_RS07725	COG1442	glycosyl transferase family 8
SK637_RS07740	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SK637_RS07800	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SK637_RS07805	COG0439	Biotin carboxylase
SK637_RS07820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SK637_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
SK637_RS07830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SK637_RS07840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SK637_RS07855	COG1024	Enoyl-CoA hydratase
SK637_RS07865	COG0527	aspartate kinase activity
SK637_RS07895	COG1115	amino acid carrier protein
SK637_RS07905	COG4193	domain, Protein
SK637_RS07905	COG5263	repeat protein
SK637_RS07910	COG5263	repeat protein
SK637_RS07910	COG4193	domain, Protein
SK637_RS07925	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SK637_RS07935	COG0443	Heat shock 70 kDa protein
SK637_RS07970	COG0681	Belongs to the peptidase S26 family
SK637_RS07975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SK637_RS07990	COG2197	response regulator
SK637_RS08035	COG0745	RESPONSE REGULATOR receiver
SK637_RS08040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SK637_RS08050	COG0116	Belongs to the methyltransferase superfamily
SK637_RS08080	COG4166	transmembrane transport
SK637_RS08105	COG1442	glycosyl transferase family 8
SK637_RS08105	COG1216	Glycosyl transferase, family 2
SK637_RS08110	COG1215	transferase activity, transferring glycosyl groups
SK637_RS08115	COG0438	transferase activity, transferring glycosyl groups
SK637_RS08120	COG3475	LICD family
SK637_RS08125	COG1442	glycosyl transferase family 8
SK637_RS08130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SK637_RS08135	COG0489	protein tyrosine kinase activity
SK637_RS08140	COG3944	biosynthesis protein
SK637_RS08155	COG4166	transmembrane transport
SK637_RS08160	COG0366	Alpha amylase catalytic
SK637_RS08190	COG0768	penicillin binding
SK637_RS08195	COG4839	cell division protein FtsL
SK637_RS08230	COG0386	Belongs to the glutathione peroxidase family
SK637_RS08245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SK637_RS08250	COG3620	sequence-specific DNA binding
SK637_RS08260	COG1373	ATPase (AAA superfamily
SK637_RS08280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SK637_RS08285	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SK637_RS08290	COG1668	transmembrane transport
SK637_RS08295	COG4152	abc transporter atp-binding protein
SK637_RS08305	COG0456	acetyltransferase
SK637_RS08325	COG0671	phosphoesterase, PA-phosphatase related
SK637_RS08330	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SK637_RS08345	COG1122	ATPase activity
SK637_RS08360	COG0569	domain protein
SK637_RS08365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SK637_RS08370	COG1882	Formate acetyltransferase
SK637_RS08375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SK637_RS08390	COG0765	amino acid transport
SK637_RS08405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SK637_RS08420	COG0440	acetolactate synthase activity
SK637_RS08425	COG0028	Belongs to the TPP enzyme family
SK637_RS08430	COG1461	Dihydroxyacetone kinase
SK637_RS08440	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SK637_RS08460	COG1132	(ABC) transporter
SK637_RS08485	COG0534	Mate efflux family protein
SK637_RS08500	COG1316	TRANSCRIPTIONal
SK637_RS08510	COG0802	atpase or kinase
SK637_RS08540	COG1523	belongs to the glycosyl hydrolase 13 family
SK637_RS08555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SK637_RS08560	COG2723	6-phospho-beta-galactosidase activity
SK637_RS08570	COG0750	zinc metalloprotease
SK637_RS08575	COG4589	Belongs to the CDS family
SK637_RS08580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SK637_RS08640	COG2848	UPF0210 protein
SK637_RS08645	COG3830	Belongs to the UPF0237 family
SK637_RS08655	COG0202	RNA polymerase activity
SK637_RS08660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SK637_RS08670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SK637_RS08675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SK637_RS08685	COG0201	protein transport
SK637_RS08700	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SK637_RS08720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SK637_RS08740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SK637_RS08765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SK637_RS08800	COG0602	queuosine metabolic process
SK637_RS08830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SK637_RS08840	COG0285	dihydrofolate synthase activity
SK637_RS08865	COG1393	Belongs to the ArsC family
SK637_RS08875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SK637_RS08880	COG0006	proline dipeptidase activity
SK637_RS08885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SK637_RS08910	COG2818	Glycosylase
SK637_RS08940	COG1780	Probably involved in ribonucleotide reductase function
SK637_RS08950	COG4753	response regulator
SK637_RS08950	COG2207	Transcriptional regulator
SK637_RS08955	COG2972	Histidine kinase
SK637_RS08990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SK637_RS08995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SK637_RS09000	COG1464	Belongs to the NlpA lipoprotein family
SK637_RS09005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SK637_RS09010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SK637_RS09035	COG1396	sequence-specific DNA binding
SK637_RS09040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SK637_RS09050	COG1214	PFAM Peptidase M22, glycoprotease
SK637_RS09075	COG0445	tRNA wobble uridine modification
SK637_RS09080	COG0494	nUDIX hydrolase
SK637_RS09085	COG0494	nUDIX hydrolase
SK637_RS09105	COG0137	argininosuccinate synthase activity
SK637_RS09110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SK637_RS09130	COG1388	LysM domain
SK637_RS09130	COG1705	Flagellar rod assembly protein muramidase FlgJ
SK637_RS09135	COG1760	l-serine dehydratase
SK637_RS09140	COG1760	l-serine dehydratase
SK637_RS09155	COG1216	Glycosyl transferase, family 2
SK637_RS09165	COG1695	Transcriptional regulator
SK637_RS09205	COG1653	transport
SK637_RS09210	COG0395	ABC-type sugar transport system, permease component
SK637_RS09215	COG4209	transmembrane transport
SK637_RS09230	COG0383	alpha-mannosidase activity
SK637_RS09240	COG3537	Alpha-1,2-mannosidase
SK637_RS09265	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SK637_RS09270	COG3443	Belongs to the bacterial solute-binding protein 9 family
SK637_RS09270	COG0803	Belongs to the bacterial solute-binding protein 9 family
SK637_RS09275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SK637_RS09280	COG1121	(ABC) transporter
SK637_RS09285	COG1846	Transcriptional regulator
SK637_RS09305	COG1216	Glycosyl transferase, family 2
SK637_RS09305	COG0463	Glycosyl transferase, family 2
SK637_RS09310	COG1088	dTDP-glucose 4,6-dehydratase activity
SK637_RS09325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SK637_RS09335	COG1696	Membrane protein involved in D-alanine export
SK637_RS09350	COG2211	Major facilitator Superfamily
SK637_RS09355	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SK637_RS09360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SK637_RS09380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SK637_RS09385	COG1335	isochorismatase
SK637_RS09400	COG1136	(ABC) transporter
SK637_RS09420	COG2197	response regulator
SK637_RS09430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SK637_RS09450	COG3201	nicotinamide mononucleotide transporter
SK637_RS09460	COG0542	response to heat
SK637_RS09470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SK637_RS09475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SK637_RS09480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SK637_RS09490	COG3942	CHAP domain
SK637_RS09490	COG1388	LysM domain
SK637_RS09500	COG0305	Participates in initiation and elongation during chromosome replication
SK637_RS09520	COG1040	competence protein
SK637_RS09525	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SK637_RS09530	COG1739	Uncharacterized protein family UPF0029
SK637_RS09555	COG3942	CHAP domain
SK637_RS09565	COG1792	Involved in formation and maintenance of cell shape
SK637_RS09570	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SK637_RS09575	COG1122	ATPase activity
SK637_RS09580	COG1122	ATPase activity
SK637_RS09585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SK637_RS09595	COG0612	Peptidase, M16
SK637_RS09600	COG0612	Peptidase, M16
SK637_RS09605	COG2501	S4 domain
SK637_RS09615	COG0516	GMP reductase activity
SK637_RS09615	COG0517	IMP dehydrogenase activity
SK637_RS09620	COG0180	Tryptophanyl-tRNA synthetase
SK637_RS09625	COG0488	(ABC) transporter
SK637_RS09635	COG1511	domain protein
SK637_RS09635	COG1511	domain protein
SK637_RS09680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SK637_RS09685	COG1475	DNA binding