locus-tag	class	description
AXK38_RS00010	COG0592	DNA-directed DNA polymerase activity
AXK38_RS00020	COG0012	GTP binding
AXK38_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXK38_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AXK38_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AXK38_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXK38_RS00140	COG1396	sequence-specific DNA binding
AXK38_RS00180	COG0270	DNA (cytosine-5-)-methyltransferase activity
AXK38_RS00230	COG0582	viral genome integration into host DNA
AXK38_RS00345	COG5263	repeat protein
AXK38_RS00345	COG5632	N-Acetylmuramoyl-L-alanine amidase
AXK38_RS00365	COG0756	dUTP diphosphatase activity
AXK38_RS00375	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AXK38_RS00390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXK38_RS00415	COG4509	Sortase family
AXK38_RS00420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXK38_RS00420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXK38_RS00425	COG1832	CoA-binding protein
AXK38_RS00430	COG2855	membrane
AXK38_RS00435	COG0436	Aminotransferase
AXK38_RS00450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXK38_RS00480	COG2274	protein secretion by the type I secretion system
AXK38_RS00485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK38_RS00495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXK38_RS00500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AXK38_RS00505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AXK38_RS00510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXK38_RS00520	COG0138	bifunctional purine biosynthesis protein purh
AXK38_RS00535	COG0151	Belongs to the GarS family
AXK38_RS00540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AXK38_RS00565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXK38_RS00570	COG3583	domain protein
AXK38_RS00570	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AXK38_RS00570	COG3064	Membrane
AXK38_RS00585	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXK38_RS00590	COG3715	PTS system
AXK38_RS00595	COG3716	PTS system mannose fructose sorbose family IID component
AXK38_RS00605	COG2222	sugar isomerase
AXK38_RS00615	COG2514	catechol 2,3-dioxygenase activity
AXK38_RS00620	COG1937	Protein conserved in bacteria
AXK38_RS00625	COG0425	Belongs to the sulfur carrier protein TusA family
AXK38_RS00625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXK38_RS00630	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXK38_RS00635	COG0425	Belongs to the sulfur carrier protein TusA family
AXK38_RS00635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXK38_RS00640	COG0110	maltose O-acetyltransferase activity
AXK38_RS00655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXK38_RS00660	COG0569	domain protein
AXK38_RS00670	COG1215	transferase activity, transferring glycosyl groups
AXK38_RS00685	COG5002	protein histidine kinase activity
AXK38_RS00705	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AXK38_RS00710	COG3177	Filamentation induced by cAMP protein fic
AXK38_RS00735	COG2801	Transposase and inactivated derivatives
AXK38_RS00745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXK38_RS00760	COG2151	metal-sulfur cluster biosynthetic enzyme
AXK38_RS00780	COG0124	histidyl-tRNA synthetase
AXK38_RS00790	COG1476	TRANSCRIPTIONal
AXK38_RS00835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXK38_RS00840	COG1609	Transcriptional regulator
AXK38_RS00845	COG5521	maltodextrose utilization protein MalA
AXK38_RS00850	COG3833	ABC-type maltose transport systems, permease component
AXK38_RS00855	COG1175	transmembrane transport
AXK38_RS00860	COG2182	Extracellular solute-binding protein
AXK38_RS00865	COG1640	4-alpha-glucanotransferase
AXK38_RS00870	COG0058	SHG alpha-glucan phosphorylase activity
AXK38_RS00875	COG2226	methyltransferase
AXK38_RS00885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXK38_RS00885	COG4499	WXG100 protein secretion system (Wss), protein YukC
AXK38_RS00890	COG0697	spore germination
AXK38_RS00905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXK38_RS00915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AXK38_RS00935	COG1438	arginine binding
AXK38_RS00945	COG1132	(ABC) transporter
AXK38_RS00950	COG1132	(ABC) transporter
AXK38_RS00955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AXK38_RS00965	COG0166	Belongs to the GPI family
AXK38_RS01060	COG0582	viral genome integration into host DNA
AXK38_RS01110	COG0534	Mate efflux family protein
AXK38_RS01115	COG0546	phosphoglycolate phosphatase activity
AXK38_RS01130	COG3759	membrane
AXK38_RS01135	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AXK38_RS01180	COG1335	isochorismatase
AXK38_RS01190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AXK38_RS01195	COG1459	type II secretion system
AXK38_RS01200	COG4537	Required for transformation and DNA binding
AXK38_RS01245	COG0706	membrane insertase activity
AXK38_RS01250	COG1847	R3H domain protein
AXK38_RS01265	COG3037	sugar-specific permease SgaT UlaA
AXK38_RS01275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK38_RS01305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXK38_RS01315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AXK38_RS01325	COG1454	alcohol dehydrogenase
AXK38_RS01325	COG1012	belongs to the aldehyde dehydrogenase family
AXK38_RS01340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXK38_RS01345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXK38_RS01460	COG1131	(ABC) transporter
AXK38_RS01465	COG0842	Transport permease protein
AXK38_RS01470	COG4585	Histidine kinase
AXK38_RS01475	COG2197	response regulator
AXK38_RS01495	COG2176	DNA-directed DNA polymerase activity
AXK38_RS01505	COG2309	aminopeptidase activity
AXK38_RS01510	COG2261	transglycosylase associated protein
AXK38_RS01515	COG1187	pseudouridine synthase activity
AXK38_RS01525	COG3579	cysteine-type endopeptidase activity
AXK38_RS01535	COG3716	PTS system mannose fructose sorbose family IID component
AXK38_RS01540	COG3715	PTS system
AXK38_RS01550	COG1064	alcohol dehydrogenase
AXK38_RS01555	COG0561	phosphatase activity
AXK38_RS01560	COG2252	PERMEase
AXK38_RS01570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXK38_RS01575	COG0285	dihydrofolate synthase activity
AXK38_RS01585	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AXK38_RS01585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AXK38_RS01595	COG1609	Transcriptional regulator
AXK38_RS01605	COG0252	asparaginase activity
AXK38_RS01610	COG0561	phosphatase activity
AXK38_RS01615	COG0589	response to stress
AXK38_RS01625	COG0436	Aminotransferase
AXK38_RS01635	COG4166	transmembrane transport
AXK38_RS01640	COG0531	amino acid
AXK38_RS01665	COG0582	viral genome integration into host DNA
AXK38_RS01670	COG0084	hydrolase, TatD family'
AXK38_RS01675	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AXK38_RS01680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXK38_RS01685	COG1162	GTPase activity
AXK38_RS01695	COG1564	THIamine pyrophosphokinase
AXK38_RS01705	COG3481	metal-dependent phosphohydrolase, HD sub domain
AXK38_RS01710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXK38_RS01720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AXK38_RS01730	COG1254	Belongs to the acylphosphatase family
AXK38_RS01735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXK38_RS01750	COG0742	ribosomal rna small subunit methyltransferase
AXK38_RS01760	COG3480	Lon protease (S16) C-terminal proteolytic domain
AXK38_RS01770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXK38_RS01785	COG1253	flavin adenine dinucleotide binding
AXK38_RS01795	COG4166	transmembrane transport
AXK38_RS01800	COG0601	transmembrane transport
AXK38_RS01805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXK38_RS01810	COG0444	Belongs to the ABC transporter superfamily
AXK38_RS01815	COG4608	Belongs to the ABC transporter superfamily
AXK38_RS01825	COG4120	Belongs to the binding-protein-dependent transport system permease family
AXK38_RS01830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXK38_RS01835	COG0366	Alpha amylase catalytic
AXK38_RS01850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AXK38_RS01860	COG0517	IMP dehydrogenase activity
AXK38_RS01880	COG1187	pseudouridine synthase activity
AXK38_RS01890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXK38_RS01895	COG1363	Peptidase, m42
AXK38_RS01910	COG3583	domain protein
AXK38_RS01910	COG3064	Membrane
AXK38_RS01910	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AXK38_RS01925	COG0789	Transcriptional regulator
AXK38_RS01930	COG0174	glutamine synthetase
AXK38_RS01975	COG0484	heat shock protein binding
AXK38_RS01985	COG0537	adenosine 5'-monophosphoramidase activity
AXK38_RS01990	COG1131	(ABC) transporter
AXK38_RS02010	COG3290	protein histidine kinase activity
AXK38_RS02050	COG1266	CAAX protease self-immunity
AXK38_RS02070	COG0195	Participates in both transcription termination and antitermination
AXK38_RS02075	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AXK38_RS02150	COG0519	Catalyzes the synthesis of GMP from XMP
AXK38_RS02160	COG0525	valine-tRNA ligase activity
AXK38_RS02200	COG0504	CTP synthase activity
AXK38_RS02215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXK38_RS02220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXK38_RS02225	COG4221	oxidoreductase activity
AXK38_RS02265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXK38_RS02395	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AXK38_RS02395	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AXK38_RS02405	COG1846	Transcriptional regulator
AXK38_RS02410	COG1125	glycine betaine transport
AXK38_RS02410	COG0517	IMP dehydrogenase activity
AXK38_RS02415	COG1174	glycine betaine transport
AXK38_RS02420	COG3201	nicotinamide mononucleotide transporter
AXK38_RS02435	COG1230	cation diffusion facilitator family transporter
AXK38_RS02440	COG0789	Transcriptional regulator
AXK38_RS02445	COG1063	alcohol dehydrogenase
AXK38_RS02450	COG1609	Transcriptional regulator
AXK38_RS02455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AXK38_RS02460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXK38_RS02465	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AXK38_RS02475	COG2233	PERMEase
AXK38_RS02490	COG0708	Exodeoxyribonuclease III
AXK38_RS02505	COG1132	(ABC) transporter
AXK38_RS02510	COG1132	(ABC) transporter
AXK38_RS02515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXK38_RS02520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AXK38_RS02525	COG0133	tryptophan synthase activity
AXK38_RS02535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXK38_RS02540	COG0512	Glutamine amidotransferase of anthranilate synthase
AXK38_RS02570	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AXK38_RS02590	COG0628	permease
AXK38_RS02610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXK38_RS02625	COG2264	protein methyltransferase activity
AXK38_RS02630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXK38_RS02635	COG1164	Oligoendopeptidase f
AXK38_RS02645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXK38_RS02660	COG0720	synthase
AXK38_RS02670	COG3118	belongs to the thioredoxin family
AXK38_RS02690	COG1346	cytolysis
AXK38_RS02700	COG1131	(ABC) transporter
AXK38_RS02705	COG1725	Transcriptional regulator
AXK38_RS02720	COG1484	DNA-dependent DNA replication
AXK38_RS02725	COG0778	Nitroreductase
AXK38_RS02750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXK38_RS02755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXK38_RS02770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXK38_RS02780	COG3458	cephalosporin-C deacetylase activity
AXK38_RS02800	COG1175	transmembrane transport
AXK38_RS02805	COG0395	ABC-type sugar transport system, permease component
AXK38_RS02810	COG2731	YhcH YjgK YiaL family protein
AXK38_RS02820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXK38_RS02845	COG0768	penicillin binding
AXK38_RS02860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXK38_RS02865	COG1051	belongs to the nudix hydrolase family
AXK38_RS02885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AXK38_RS02905	COG3599	regulation of cell shape
AXK38_RS02930	COG0577	efflux transmembrane transporter activity
AXK38_RS02930	COG1136	(ABC) transporter
AXK38_RS02945	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AXK38_RS02965	COG3590	peptidase
AXK38_RS02975	COG2247	cell wall binding repeat
AXK38_RS02975	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXK38_RS03020	COG1959	2 iron, 2 sulfur cluster binding
AXK38_RS03045	COG0745	RESPONSE REGULATOR receiver
AXK38_RS03050	COG5002	protein histidine kinase activity
AXK38_RS03055	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AXK38_RS03070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXK38_RS03095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK38_RS03115	COG0204	Acyl-transferase
AXK38_RS03120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXK38_RS03125	COG2384	SAM-dependent methyltransferase
AXK38_RS03130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXK38_RS03135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXK38_RS03140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXK38_RS03145	COG0463	Glycosyl transferase, family 2
AXK38_RS03160	COG2824	Alkylphosphonate utilization operon protein PhnA
AXK38_RS03180	COG0351	phosphomethylpyrimidine kinase
AXK38_RS03185	COG4720	Psort location CytoplasmicMembrane, score
AXK38_RS03190	COG0006	proline dipeptidase activity
AXK38_RS03195	COG3442	glutamine amidotransferase
AXK38_RS03200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXK38_RS03205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXK38_RS03210	COG0513	Belongs to the DEAD box helicase family
AXK38_RS03215	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AXK38_RS03220	COG1335	isochorismatase
AXK38_RS03230	COG0577	efflux transmembrane transporter activity
AXK38_RS03235	COG1136	(ABC) transporter
AXK38_RS03240	COG0577	efflux transmembrane transporter activity
AXK38_RS03245	COG0745	RESPONSE REGULATOR receiver
AXK38_RS03250	COG5002	protein histidine kinase activity
AXK38_RS03255	COG0191	fructose-bisphosphate aldolase activity
AXK38_RS03260	COG2020	methyltransferase activity
AXK38_RS03265	COG4555	ABC transporter
AXK38_RS03280	COG1404	Belongs to the peptidase S8 family
AXK38_RS03295	COG3250	beta-galactosidase activity
AXK38_RS03305	COG1242	4 iron, 4 sulfur cluster binding
AXK38_RS03310	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AXK38_RS03320	COG0025	NhaP-type Na H and K H
AXK38_RS03350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXK38_RS03390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXK38_RS03400	COG0647	UMP catabolic process
AXK38_RS03410	COG1393	Belongs to the ArsC family
AXK38_RS03420	COG0483	inositol monophosphate 1-phosphatase activity
AXK38_RS03425	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AXK38_RS03425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXK38_RS03430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXK38_RS03435	COG0573	inorganic phosphate transmembrane transporter activity
AXK38_RS03440	COG0581	inorganic phosphate transmembrane transporter activity
AXK38_RS03445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXK38_RS03450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXK38_RS03455	COG0704	Plays a role in the regulation of phosphate uptake
AXK38_RS03460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK38_RS03465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXK38_RS03470	COG3527	Alpha-acetolactate decarboxylase
AXK38_RS03485	COG3842	ATPase activity
AXK38_RS03510	COG0515	serine threonine protein kinase
AXK38_RS03510	COG2815	serine threonine protein kinase
AXK38_RS03530	COG1131	(ABC) transporter
AXK38_RS03545	COG1199	ATP-dependent helicase activity
AXK38_RS03545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXK38_RS03550	COG0772	Belongs to the SEDS family
AXK38_RS03555	COG0693	protein deglycase activity
AXK38_RS03565	COG0187	DNA topoisomerase II activity
AXK38_RS03570	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AXK38_RS03595	COG0542	response to heat
AXK38_RS03600	COG4703	Protein of unknown function (DUF1797)
AXK38_RS03605	COG0765	amino acid transport
AXK38_RS03610	COG1126	abc transporter atp-binding protein
AXK38_RS03615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AXK38_RS03620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXK38_RS03625	COG1686	Belongs to the peptidase S11 family
AXK38_RS03630	COG0628	permease
AXK38_RS03650	COG0673	inositol 2-dehydrogenase activity
AXK38_RS03675	COG0583	DNA-binding transcription factor activity
AXK38_RS03680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AXK38_RS03685	COG0564	pseudouridine synthase activity
AXK38_RS03690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AXK38_RS03705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXK38_RS03715	COG0470	DNA polymerase III
AXK38_RS03735	COG0528	UMP kinase activity
AXK38_RS03745	COG2996	Protein conserved in bacteria
AXK38_RS03755	COG1702	phosphate starvation-inducible protein PhoH
AXK38_RS03760	COG0686	Belongs to the AlaDH PNT family
AXK38_RS03770	COG1596	polysaccharide export
AXK38_RS03770	COG1555	photosystem II stabilization
AXK38_RS03775	COG2333	competence protein COMEC
AXK38_RS03775	COG0658	competence protein
AXK38_RS03785	COG1131	(ABC) transporter
AXK38_RS03815	COG0543	2 iron, 2 sulfur cluster binding
AXK38_RS03820	COG0167	dihydroorotate dehydrogenase activity
AXK38_RS03825	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AXK38_RS03835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AXK38_RS03845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AXK38_RS03850	COG0237	dephospho-CoA kinase activity
AXK38_RS03855	COG2814	Major facilitator Superfamily
AXK38_RS03860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXK38_RS03870	COG0557	exoribonuclease II activity
AXK38_RS03880	COG0500	methyltransferase
AXK38_RS03880	COG3615	Tellurite resistance protein tehB
AXK38_RS03900	COG4122	O-methyltransferase activity
AXK38_RS03910	COG0772	Belongs to the SEDS family
AXK38_RS03915	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AXK38_RS03935	COG0358	DNA primase activity
AXK38_RS03940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXK38_RS03945	COG2151	metal-sulfur cluster biosynthetic enzyme
AXK38_RS03950	COG0438	transferase activity, transferring glycosyl groups
AXK38_RS03955	COG0438	transferase activity, transferring glycosyl groups
AXK38_RS03985	COG1126	abc transporter atp-binding protein
AXK38_RS04005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXK38_RS04020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXK38_RS04025	COG0494	nUDIX hydrolase
AXK38_RS04035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXK38_RS04045	COG2176	DNA-directed DNA polymerase activity
AXK38_RS04050	COG0584	glycerophosphoryl diester phosphodiesterase
AXK38_RS04060	COG1104	cysteine desulfurase activity
AXK38_RS04070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXK38_RS04075	COG4166	transmembrane transport
AXK38_RS04095	COG0539	negative regulation of cytoplasmic translation
AXK38_RS04105	COG1956	GAF domain-containing protein
AXK38_RS04110	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXK38_RS04125	COG0719	Fe-S assembly protein
AXK38_RS04130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXK38_RS04140	COG0719	Fe-S assembly protein
AXK38_RS04145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXK38_RS04155	COG2822	iron ion transport
AXK38_RS04160	COG2837	iron assimilation
AXK38_RS04165	COG0672	)-iron permease
AXK38_RS04170	COG0805	protein transport
AXK38_RS04175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AXK38_RS04185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXK38_RS04190	COG0716	FMN binding
AXK38_RS04195	COG0077	Prephenate dehydratase
AXK38_RS04195	COG1605	Chorismate mutase
AXK38_RS04200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXK38_RS04205	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXK38_RS04260	COG3942	CHAP domain
AXK38_RS04260	COG1388	LysM domain
AXK38_RS04320	COG3843	relaxase mobilization nuclease domain protein
AXK38_RS04360	COG1078	dGTPase activity
AXK38_RS04375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXK38_RS04380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXK38_RS04425	COG1704	LemA family
AXK38_RS04460	COG0561	phosphatase activity
AXK38_RS04480	COG2801	Transposase and inactivated derivatives
AXK38_RS04510	COG1063	alcohol dehydrogenase
AXK38_RS04525	COG4750	Nucleotidyl transferase
AXK38_RS04530	COG0758	DNA mediated transformation
AXK38_RS04535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXK38_RS04540	COG2832	Protein of unknown function (DUF454)
AXK38_RS04545	COG3142	Participates in the control of copper homeostasis
AXK38_RS04560	COG0473	3-isopropylmalate dehydrogenase activity
AXK38_RS04575	COG0066	3-isopropylmalate dehydratase activity
AXK38_RS04595	COG0571	ribonuclease III activity
AXK38_RS04600	COG1196	nuclear chromosome segregation
AXK38_RS04605	COG0561	phosphatase activity
AXK38_RS04610	COG0561	phosphatase activity
AXK38_RS04615	COG0552	protein localization to endoplasmic reticulum
AXK38_RS04625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AXK38_RS04630	COG1126	abc transporter atp-binding protein
AXK38_RS04635	COG0765	amino acid transport
AXK38_RS04645	COG0556	nucleotide-excision repair
AXK38_RS04650	COG2816	NAD+ diphosphatase activity
AXK38_RS04670	COG1132	(ABC) transporter
AXK38_RS04675	COG1131	(ABC) transporter
AXK38_RS04715	COG1827	regulation of RNA biosynthetic process
AXK38_RS04725	COG4684	Psort location CytoplasmicMembrane, score
AXK38_RS04730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXK38_RS04735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXK38_RS04745	COG0210	DNA helicase
AXK38_RS04755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AXK38_RS04775	COG1104	cysteine desulfurase activity
AXK38_RS04780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXK38_RS04790	COG2357	RelA SpoT domain protein
AXK38_RS04800	COG0564	pseudouridine synthase activity
AXK38_RS04805	COG0280	phosphate acetyltransferase
AXK38_RS04820	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXK38_RS04825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AXK38_RS04830	COG1970	mechanosensitive ion channel activity
AXK38_RS04840	COG4708	membrane
AXK38_RS04850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXK38_RS04860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AXK38_RS04865	COG1942	4-Oxalocrotonate Tautomerase
AXK38_RS04870	COG1435	thymidine kinase activity
AXK38_RS04880	COG2890	protein-(glutamine-N5) methyltransferase activity
AXK38_RS04905	COG0741	lytic transglycosylase activity
AXK38_RS04915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXK38_RS04950	COG0135	phosphoribosylanthranilate isomerase activity
AXK38_RS04965	COG1597	lipid kinase activity
AXK38_RS04970	COG0366	Alpha amylase catalytic
AXK38_RS04985	COG3689	TIGRFAM TIGR03943 family protein
AXK38_RS04990	COG0701	Predicted permease
AXK38_RS05000	COG2183	response to ionizing radiation
AXK38_RS05015	COG1136	(ABC) transporter
AXK38_RS05020	COG0577	efflux transmembrane transporter activity
AXK38_RS05030	COG1982	Orn Lys Arg decarboxylase major
AXK38_RS05035	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AXK38_RS05055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXK38_RS05065	COG2826	transposase and inactivated derivatives, IS30 family
AXK38_RS05070	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AXK38_RS05075	COG3421	Type III restriction
AXK38_RS05105	COG0745	RESPONSE REGULATOR receiver
AXK38_RS05110	COG2205	protein histidine kinase activity
AXK38_RS05120	COG1131	(ABC) transporter
AXK38_RS05125	COG0561	phosphatase activity
AXK38_RS05135	COG1673	EVE domain
AXK38_RS05155	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AXK38_RS05155	COG3583	domain protein
AXK38_RS05160	COG3064	Membrane
AXK38_RS05175	COG0270	DNA (cytosine-5-)-methyltransferase activity
AXK38_RS05280	COG0488	(ABC) transporter
AXK38_RS05330	COG0791	NLP P60 protein
AXK38_RS05330	COG0741	lytic transglycosylase activity
AXK38_RS05360	COG2946	Replication initiation factor
AXK38_RS05365	COG1674	ftsk spoiiie
AXK38_RS05385	COG1396	sequence-specific DNA binding
AXK38_RS05420	COG1396	sequence-specific DNA binding
AXK38_RS05425	COG0542	response to heat
AXK38_RS05450	COG0366	Alpha amylase catalytic
AXK38_RS05465	COG1396	sequence-specific DNA binding
AXK38_RS05470	COG0542	response to heat
AXK38_RS05505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK38_RS05510	COG2274	protein secretion by the type I secretion system
AXK38_RS05600	COG1136	(ABC) transporter
AXK38_RS05615	COG2197	response regulator
AXK38_RS05650	COG3843	relaxase mobilization nuclease domain protein
AXK38_RS05655	COG1396	sequence-specific DNA binding
AXK38_RS05665	COG0582	viral genome integration into host DNA
AXK38_RS05670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AXK38_RS05680	COG0038	chloride channel
AXK38_RS05695	COG0582	viral genome integration into host DNA
AXK38_RS05715	COG0560	Phosphoserine phosphatase
AXK38_RS05725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AXK38_RS05735	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXK38_RS05740	COG1523	belongs to the glycosyl hydrolase 13 family
AXK38_RS05760	COG0488	(ABC) transporter
AXK38_RS05765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXK38_RS05780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AXK38_RS05790	COG0745	RESPONSE REGULATOR receiver
AXK38_RS05795	COG1194	a g-specific adenine glycosylase
AXK38_RS05805	COG1307	EDD domain protein, DegV family
AXK38_RS05810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXK38_RS05815	COG0196	riboflavin kinase activity
AXK38_RS05825	COG0505	Belongs to the CarA family
AXK38_RS05840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXK38_RS05855	COG0488	(ABC) transporter
AXK38_RS05870	COG0803	Belongs to the bacterial solute-binding protein 9 family
AXK38_RS05870	COG3443	Belongs to the bacterial solute-binding protein 9 family
AXK38_RS05880	COG0531	amino acid
AXK38_RS05885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXK38_RS05890	COG0785	Cytochrome C biogenesis protein
AXK38_RS05895	COG0024	Methionine aminopeptidase
AXK38_RS05900	COG4109	DRTGG domain
AXK38_RS05910	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXK38_RS05915	COG0095	Lipoate-protein ligase
AXK38_RS05920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXK38_RS05925	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXK38_RS05930	COG0022	dehydrogenase e1 component
AXK38_RS05935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXK38_RS05940	COG0534	Mate efflux family protein
AXK38_RS05945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXK38_RS05950	COG1051	belongs to the nudix hydrolase family
AXK38_RS05960	COG1011	Hydrolase
AXK38_RS05980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK38_RS05985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXK38_RS05990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXK38_RS05995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXK38_RS06030	COG3711	transcriptional antiterminator
AXK38_RS06035	COG3684	Belongs to the aldolase LacD family
AXK38_RS06060	COG3775	system Galactitol-specific IIC component
AXK38_RS06080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXK38_RS06085	COG0497	DNA recombination
AXK38_RS06090	COG1438	arginine binding
AXK38_RS06095	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AXK38_RS06120	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXK38_RS06145	COG3764	Sortase (surface protein transpeptidase)
AXK38_RS06150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXK38_RS06155	COG0039	L-malate dehydrogenase activity
AXK38_RS06160	COG0469	pyruvate kinase activity
AXK38_RS06175	COG2936	dipeptidyl-peptidase activity
AXK38_RS06180	COG1438	arginine binding
AXK38_RS06185	COG0697	spore germination
AXK38_RS06185	COG1674	ftsk spoiiie
AXK38_RS06190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK38_RS06190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK38_RS06190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK38_RS06195	COG1105	Belongs to the carbohydrate kinase PfkB family
AXK38_RS06200	COG1349	DNA-binding transcription factor activity
AXK38_RS06210	COG2801	Transposase and inactivated derivatives
AXK38_RS06250	COG3976	FMN-binding domain protein
AXK38_RS06250	COG0431	NADPH-dependent FMN reductase
AXK38_RS06250	COG1053	succinate dehydrogenase
AXK38_RS06275	COG0656	L-ascorbic acid biosynthetic process
AXK38_RS06280	COG0726	polysaccharide deacetylase
AXK38_RS06295	COG2801	Transposase and inactivated derivatives
AXK38_RS06300	COG1136	(ABC) transporter
AXK38_RS06315	COG5002	protein histidine kinase activity
AXK38_RS06320	COG0745	RESPONSE REGULATOR receiver
AXK38_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
AXK38_RS06360	COG0628	permease
AXK38_RS06370	COG4166	transmembrane transport
AXK38_RS06375	COG2706	6-phosphogluconolactonase activity
AXK38_RS06420	COG0826	peptidase U32
AXK38_RS06430	COG2188	Transcriptional regulator
AXK38_RS06440	COG0697	spore germination
AXK38_RS06445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXK38_RS06460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXK38_RS06490	COG0187	DNA topoisomerase II activity
AXK38_RS06505	COG2801	Transposase and inactivated derivatives
AXK38_RS06515	COG1079	Belongs to the binding-protein-dependent transport system permease family
AXK38_RS06520	COG4603	Belongs to the binding-protein-dependent transport system permease family
AXK38_RS06525	COG3845	ABC transporter
AXK38_RS06530	COG1744	ABC transporter substrate-binding protein PnrA-like
AXK38_RS06535	COG0295	cytidine deaminase activity
AXK38_RS06545	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AXK38_RS06550	COG2813	Specifically methylates the guanine in position
AXK38_RS06580	COG0813	purine-nucleoside phosphorylase activity
AXK38_RS06600	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AXK38_RS06625	COG0492	ferredoxin-NADP+ reductase activity
AXK38_RS06635	COG1126	abc transporter atp-binding protein
AXK38_RS06645	COG1393	Belongs to the ArsC family
AXK38_RS06650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXK38_RS06665	COG1272	protein, Hemolysin III
AXK38_RS06670	COG4989	oxidoreductase activity
AXK38_RS06675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXK38_RS06675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXK38_RS06680	COG0577	efflux transmembrane transporter activity
AXK38_RS06685	COG1136	(ABC) transporter
AXK38_RS06690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK38_RS06695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXK38_RS06700	COG1268	BioY protein
AXK38_RS06705	COG4443	Transcriptional Coactivator p15 (PC4)
AXK38_RS06715	COG1328	CTP reductase activity
AXK38_RS06715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AXK38_RS06750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AXK38_RS06755	COG0488	(ABC) transporter
AXK38_RS06765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXK38_RS06770	COG4470	Protein conserved in bacteria
AXK38_RS06775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXK38_RS06785	COG0167	dihydroorotate dehydrogenase activity
AXK38_RS06790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXK38_RS06800	COG1309	transcriptional regulator
AXK38_RS06805	COG2130	NADP-dependent
AXK38_RS06815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AXK38_RS06820	COG0402	S-adenosylhomocysteine deaminase activity
AXK38_RS06830	COG1132	(ABC) transporter
AXK38_RS06835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXK38_RS06835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXK38_RS06875	COG3475	LICD family
AXK38_RS06880	COG1442	glycosyl transferase family 8
AXK38_RS06880	COG1216	Glycosyl transferase, family 2
AXK38_RS06885	COG3475	LICD family
AXK38_RS06895	COG0077	Prephenate dehydratase
AXK38_RS06915	COG0287	Prephenate dehydrogenase
AXK38_RS06940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AXK38_RS06945	COG1368	sulfuric ester hydrolase activity
AXK38_RS06955	COG0513	Belongs to the DEAD box helicase family
AXK38_RS06965	COG1263	PTS System
AXK38_RS06965	COG2190	(PTS) system
AXK38_RS06965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXK38_RS06970	COG2177	Part of the ABC transporter FtsEX involved in
AXK38_RS06975	COG2884	Cell division ATP-binding protein ftsE
AXK38_RS06980	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AXK38_RS06985	COG0617	tRNA 3'-terminal CCA addition
AXK38_RS06985	COG0517	IMP dehydrogenase activity
AXK38_RS06985	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXK38_RS07025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AXK38_RS07030	COG2131	deaminase
AXK38_RS07040	COG1307	EDD domain protein, DegV family
AXK38_RS07045	COG2081	HI0933 family
AXK38_RS07055	COG0789	Transcriptional regulator
AXK38_RS07060	COG0733	neurotransmitter:sodium symporter activity
AXK38_RS07065	COG1482	cell wall glycoprotein biosynthetic process
AXK38_RS07080	COG0028	Belongs to the TPP enzyme family
AXK38_RS07085	COG2217	Heavy metal translocating P-type atpase
AXK38_RS07105	COG0352	thiamine-phosphate diphosphorylase activity
AXK38_RS07120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXK38_RS07130	COG4172	Belongs to the ABC transporter superfamily
AXK38_RS07140	COG0352	thiamine-phosphate diphosphorylase activity
AXK38_RS07145	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AXK38_RS07155	COG1304	FMN binding
AXK38_RS07165	COG4215	(ABC) transporter
AXK38_RS07170	COG1126	abc transporter atp-binding protein
AXK38_RS07175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK38_RS07190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AXK38_RS07210	COG1217	gtp-binding protein TYPA
AXK38_RS07215	COG1187	pseudouridine synthase activity
AXK38_RS07220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXK38_RS07235	COG0300	oxidoreductase activity
AXK38_RS07245	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AXK38_RS07250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXK38_RS07270	COG1940	carbohydrate kinase activity
AXK38_RS07280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXK38_RS07285	COG3064	Membrane
AXK38_RS07295	COG2972	Histidine kinase
AXK38_RS07300	COG4753	response regulator
AXK38_RS07300	COG2207	Transcriptional regulator
AXK38_RS07305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXK38_RS07305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXK38_RS07310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXK38_RS07315	COG0785	Cytochrome C biogenesis protein
AXK38_RS07335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AXK38_RS07345	COG1113	amino acid transport
AXK38_RS07355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AXK38_RS07380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXK38_RS07385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AXK38_RS07390	COG0626	cystathionine gamma-synthase activity
AXK38_RS07395	COG4166	transmembrane transport
AXK38_RS07400	COG2244	polysaccharide biosynthetic process
AXK38_RS07405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXK38_RS07445	COG2827	Endonuclease containing a URI domain
AXK38_RS07450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AXK38_RS07455	COG1098	S1 RNA binding domain
AXK38_RS07470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AXK38_RS07475	COG0629	single-stranded DNA binding
AXK38_RS07485	COG0017	Asparaginyl-tRNA synthetase
AXK38_RS07490	COG0436	Aminotransferase
AXK38_RS07510	COG3250	beta-galactosidase activity
AXK38_RS07520	COG0366	Alpha amylase catalytic
AXK38_RS07520	COG0366	Alpha amylase catalytic
AXK38_RS07540	COG0242	peptide deformylase activity
AXK38_RS07545	COG0625	glutathione transferase activity
AXK38_RS07555	COG0463	Glycosyl transferase, family 2
AXK38_RS07570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AXK38_RS07575	COG0488	(ABC) transporter
AXK38_RS07580	COG0617	tRNA 3'-terminal CCA addition
AXK38_RS07590	COG1307	EDD domain protein, DegV family
AXK38_RS07610	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AXK38_RS07615	COG0492	ferredoxin-NADP+ reductase activity
AXK38_RS07625	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AXK38_RS07635	COG0251	oxidation-reduction process
AXK38_RS07655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AXK38_RS07665	COG3583	domain protein
AXK38_RS07665	COG3583	domain protein
AXK38_RS07675	COG5263	repeat protein
AXK38_RS07675	COG4193	domain, Protein
AXK38_RS07685	COG3935	DnaD domain protein
AXK38_RS07720	COG1363	Peptidase, m42
AXK38_RS07725	COG1114	Component of the transport system for branched-chain amino acids
AXK38_RS07735	COG1573	uracil-dna glycosylase
AXK38_RS07755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK38_RS07795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AXK38_RS07795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXK38_RS07805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK38_RS07810	COG0765	amino acid transport
AXK38_RS07815	COG0765	amino acid transport
AXK38_RS07820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK38_RS07825	COG3842	ATPase activity
AXK38_RS07835	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AXK38_RS07840	COG0215	cysteine-tRNA ligase activity
AXK38_RS07850	COG1045	serine acetyltransferase
AXK38_RS07865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXK38_RS07870	COG3620	sequence-specific DNA binding
AXK38_RS07925	COG1940	carbohydrate kinase activity
AXK38_RS07930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXK38_RS07930	COG1263	PTS System
AXK38_RS07930	COG2190	(PTS) system
AXK38_RS07935	COG1621	beta-fructofuranosidase activity
AXK38_RS07940	COG1609	Transcriptional regulator
AXK38_RS07950	COG3425	synthase
AXK38_RS07965	COG0515	serine threonine protein kinase
AXK38_RS07965	COG2815	serine threonine protein kinase
AXK38_RS07970	COG0631	protein serine/threonine phosphatase activity
AXK38_RS07975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXK38_RS07975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXK38_RS07985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXK38_RS07995	COG0194	GDP metabolic process
AXK38_RS08020	COG2226	methyltransferase
AXK38_RS08025	COG0799	negative regulation of ribosome biogenesis
AXK38_RS08030	COG1713	HD superfamily hydrolase involved in NAD metabolism
AXK38_RS08035	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AXK38_RS08040	COG1534	Rna-binding protein
AXK38_RS08045	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AXK38_RS08060	COG0668	transmembrane transport
AXK38_RS08065	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AXK38_RS08085	COG0438	transferase activity, transferring glycosyl groups
AXK38_RS08090	COG0438	transferase activity, transferring glycosyl groups
AXK38_RS08095	COG0653	protein targeting
AXK38_RS08115	COG0201	protein transport
AXK38_RS08120	COG1442	glycosyl transferase family 8
AXK38_RS08125	COG1442	glycosyl transferase family 8
AXK38_RS08130	COG1442	glycosyl transferase family 8
AXK38_RS08135	COG0438	transferase activity, transferring glycosyl groups
AXK38_RS08140	COG1442	glycosyl transferase family 8
AXK38_RS08145	COG1442	glycosyl transferase family 8
AXK38_RS08160	COG1442	glycosyl transferase family 8
AXK38_RS08160	COG1216	Glycosyl transferase, family 2
AXK38_RS08165	COG1216	Glycosyl transferase, family 2
AXK38_RS08165	COG1442	glycosyl transferase family 8
AXK38_RS08220	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXK38_RS08260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AXK38_RS08265	COG0439	Biotin carboxylase
AXK38_RS08280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXK38_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
AXK38_RS08290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXK38_RS08300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXK38_RS08310	COG1846	Transcriptional regulator
AXK38_RS08315	COG1024	Enoyl-CoA hydratase
AXK38_RS08320	COG0527	aspartate kinase activity
AXK38_RS08345	COG1115	amino acid carrier protein
AXK38_RS08370	COG0681	Belongs to the peptidase S26 family
AXK38_RS08375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXK38_RS08390	COG2197	response regulator
AXK38_RS08395	COG4585	Histidine kinase
AXK38_RS08420	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AXK38_RS08440	COG0745	RESPONSE REGULATOR receiver
AXK38_RS08445	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AXK38_RS08455	COG0116	Belongs to the methyltransferase superfamily
AXK38_RS08480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXK38_RS08485	COG4166	transmembrane transport
AXK38_RS08490	COG0562	UDP-galactopyranose mutase
AXK38_RS08495	COG1091	dTDP-4-dehydrorhamnose reductase activity
AXK38_RS08500	COG1088	dTDP-glucose 4,6-dehydratase activity
AXK38_RS08510	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AXK38_RS08515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AXK38_RS08530	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXK38_RS08535	COG3475	LICD family
AXK38_RS08550	COG1215	transferase activity, transferring glycosyl groups
AXK38_RS08555	COG0438	transferase activity, transferring glycosyl groups
AXK38_RS08560	COG0438	transferase activity, transferring glycosyl groups
AXK38_RS08575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXK38_RS08580	COG0489	protein tyrosine kinase activity
AXK38_RS08585	COG3944	biosynthesis protein
AXK38_RS08600	COG4166	transmembrane transport
AXK38_RS08605	COG0366	Alpha amylase catalytic
AXK38_RS08630	COG0768	penicillin binding
AXK38_RS08635	COG4839	cell division protein FtsL
AXK38_RS08660	COG0386	Belongs to the glutathione peroxidase family
AXK38_RS08665	COG3104	oligopeptide transport
AXK38_RS08735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AXK38_RS08740	COG1668	transmembrane transport
AXK38_RS08745	COG4152	abc transporter atp-binding protein
AXK38_RS08750	COG0072	phenylalanine-tRNA ligase activity
AXK38_RS08750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXK38_RS08765	COG0671	phosphoesterase, PA-phosphatase related
AXK38_RS08770	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AXK38_RS08790	COG1122	ATPase activity
AXK38_RS08805	COG0569	domain protein
AXK38_RS08810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXK38_RS08815	COG1882	Formate acetyltransferase
AXK38_RS08820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXK38_RS08835	COG0765	amino acid transport
AXK38_RS08850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXK38_RS08860	COG0440	acetolactate synthase activity
AXK38_RS08865	COG0028	Belongs to the TPP enzyme family
AXK38_RS08870	COG1461	Dihydroxyacetone kinase
AXK38_RS08880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AXK38_RS08900	COG1132	(ABC) transporter
AXK38_RS08940	COG1316	TRANSCRIPTIONal
AXK38_RS08950	COG0802	atpase or kinase
AXK38_RS09010	COG1523	belongs to the glycosyl hydrolase 13 family
AXK38_RS09020	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXK38_RS09025	COG2723	6-phospho-beta-galactosidase activity
AXK38_RS09035	COG0750	zinc metalloprotease
AXK38_RS09040	COG4589	Belongs to the CDS family
AXK38_RS09045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXK38_RS09055	COG2255	four-way junction helicase activity
AXK38_RS09075	COG1840	ABC-type Fe3 transport system, periplasmic component
AXK38_RS09080	COG3842	ATPase activity
AXK38_RS09085	COG1178	ABC-type Fe3 transport system permease component
AXK38_RS09095	COG2848	UPF0210 protein
AXK38_RS09100	COG3830	Belongs to the UPF0237 family
AXK38_RS09110	COG0202	RNA polymerase activity
AXK38_RS09115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AXK38_RS09125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXK38_RS09130	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXK38_RS09140	COG0201	protein transport
AXK38_RS09155	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AXK38_RS09175	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AXK38_RS09195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AXK38_RS09220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AXK38_RS09250	COG0602	queuosine metabolic process
AXK38_RS09280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXK38_RS09290	COG0285	dihydrofolate synthase activity
AXK38_RS09315	COG1393	Belongs to the ArsC family
AXK38_RS09320	COG0006	proline dipeptidase activity
AXK38_RS09325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXK38_RS09355	COG0519	Catalyzes the synthesis of GMP from XMP
AXK38_RS09380	COG1780	Probably involved in ribonucleotide reductase function
AXK38_RS09390	COG2207	Transcriptional regulator
AXK38_RS09390	COG4753	response regulator
AXK38_RS09395	COG2972	Histidine kinase
AXK38_RS09415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXK38_RS09420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXK38_RS09425	COG1464	Belongs to the NlpA lipoprotein family
AXK38_RS09430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK38_RS09470	COG1396	sequence-specific DNA binding
AXK38_RS09475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AXK38_RS09485	COG1214	PFAM Peptidase M22, glycoprotease
AXK38_RS09510	COG2801	Transposase and inactivated derivatives
AXK38_RS09515	COG0445	tRNA wobble uridine modification
AXK38_RS09520	COG0494	nUDIX hydrolase
AXK38_RS09560	COG2274	protein secretion by the type I secretion system
AXK38_RS09570	COG1705	Flagellar rod assembly protein muramidase FlgJ
AXK38_RS09570	COG1388	LysM domain
AXK38_RS09575	COG1760	l-serine dehydratase
AXK38_RS09580	COG1760	l-serine dehydratase
AXK38_RS09585	COG0546	phosphoglycolate phosphatase activity
AXK38_RS09595	COG2801	Transposase and inactivated derivatives
AXK38_RS09605	COG1216	Glycosyl transferase, family 2
AXK38_RS09615	COG1695	Transcriptional regulator
AXK38_RS09655	COG1653	transport
AXK38_RS09660	COG0395	ABC-type sugar transport system, permease component
AXK38_RS09665	COG4209	transmembrane transport
AXK38_RS09680	COG0383	alpha-mannosidase activity
AXK38_RS09690	COG3537	Alpha-1,2-mannosidase
AXK38_RS09715	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AXK38_RS09730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXK38_RS09735	COG1121	(ABC) transporter
AXK38_RS09740	COG1846	Transcriptional regulator
AXK38_RS09745	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AXK38_RS09755	COG1696	Membrane protein involved in D-alanine export
AXK38_RS09770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXK38_RS09775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AXK38_RS09795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXK38_RS09800	COG1335	isochorismatase
AXK38_RS09820	COG3201	nicotinamide mononucleotide transporter
AXK38_RS09830	COG0542	response to heat
AXK38_RS09835	COG4463	regulation of RNA biosynthetic process
AXK38_RS09860	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AXK38_RS09920	COG4974	Belongs to the 'phage' integrase family
AXK38_RS09925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AXK38_RS09930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXK38_RS09935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXK38_RS09945	COG1388	LysM domain
AXK38_RS09945	COG3942	CHAP domain
AXK38_RS09955	COG0305	Participates in initiation and elongation during chromosome replication
AXK38_RS09975	COG1040	competence protein
AXK38_RS09980	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AXK38_RS09985	COG1739	Uncharacterized protein family UPF0029
AXK38_RS10010	COG3942	CHAP domain
AXK38_RS10020	COG1792	Involved in formation and maintenance of cell shape
AXK38_RS10025	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AXK38_RS10030	COG1122	ATPase activity
AXK38_RS10035	COG1122	ATPase activity
AXK38_RS10040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXK38_RS10050	COG0612	Peptidase, M16
AXK38_RS10055	COG0612	Peptidase, M16
AXK38_RS10060	COG2501	S4 domain
AXK38_RS10070	COG0516	GMP reductase activity
AXK38_RS10070	COG0517	IMP dehydrogenase activity
AXK38_RS10075	COG0180	Tryptophanyl-tRNA synthetase
AXK38_RS10080	COG0488	(ABC) transporter
AXK38_RS10090	COG1511	domain protein
AXK38_RS10090	COG1511	domain protein
AXK38_RS10135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXK38_RS10140	COG1475	DNA binding