locus-tag	class	description
FSA40_RS00010	COG0592	DNA-directed DNA polymerase activity
FSA40_RS00020	COG0012	GTP binding
FSA40_RS00025	COG0193	aminoacyl-tRNA hydrolase activity
FSA40_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FSA40_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FSA40_RS00055	COG0037	tRNA processing
FSA40_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FSA40_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSA40_RS00070	COG0531	amino acid
FSA40_RS00185	COG1792	Involved in formation and maintenance of cell shape
FSA40_RS00195	COG3942	CHAP domain
FSA40_RS00200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSA40_RS00205	COG0436	Aminotransferase
FSA40_RS00210	COG1381	Involved in DNA repair and RecF pathway recombination
FSA40_RS00215	COG0416	fatty acid biosynthetic process
FSA40_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSA40_RS00225	COG2274	protein secretion by the type I secretion system
FSA40_RS00230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSA40_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSA40_RS00245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FSA40_RS00250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSA40_RS00255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FSA40_RS00265	COG0138	bifunctional purine biosynthesis protein purh
FSA40_RS00285	COG0653	protein targeting
FSA40_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FSA40_RS00320	COG1794	racemase activity, acting on amino acids and derivatives
FSA40_RS00345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSA40_RS00375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSA40_RS00410	COG0534	Mate efflux family protein
FSA40_RS00415	COG3830	Belongs to the UPF0237 family
FSA40_RS00420	COG2848	UPF0210 protein
FSA40_RS00435	COG1705	Flagellar rod assembly protein muramidase FlgJ
FSA40_RS00445	COG5492	domain, Protein
FSA40_RS00445	COG1621	beta-fructofuranosidase activity
FSA40_RS00445	COG3583	domain protein
FSA40_RS00455	COG1420	regulation of RNA biosynthetic process
FSA40_RS00460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FSA40_RS00470	COG0443	Heat shock 70 kDa protein
FSA40_RS00475	COG0484	heat shock protein binding
FSA40_RS00480	COG0101	tRNA pseudouridine synthase activity
FSA40_RS00485	COG0351	phosphomethylpyrimidine kinase
FSA40_RS00490	COG4720	Psort location CytoplasmicMembrane, score
FSA40_RS00495	COG4475	Protein of unknown function (DUF436)
FSA40_RS00500	COG0668	transmembrane transport
FSA40_RS00510	COG0544	peptidyl-prolyl cis-trans isomerase activity
FSA40_RS00520	COG3343	RNA polymerase activity
FSA40_RS00525	COG0504	CTP synthase activity
FSA40_RS00535	COG0191	fructose-bisphosphate aldolase activity
FSA40_RS00545	COG3715	PTS system
FSA40_RS00595	COG1396	sequence-specific DNA binding
FSA40_RS00605	COG1105	Belongs to the carbohydrate kinase PfkB family
FSA40_RS00610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FSA40_RS00610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA40_RS00610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FSA40_RS00615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA40_RS00615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FSA40_RS00615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FSA40_RS00620	COG3684	Belongs to the aldolase LacD family
FSA40_RS00640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FSA40_RS00645	COG0534	Mate efflux family protein
FSA40_RS00650	COG2176	DNA-directed DNA polymerase activity
FSA40_RS00655	COG1846	Transcriptional regulator
FSA40_RS00660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FSA40_RS00665	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSA40_RS00670	COG0022	dehydrogenase e1 component
FSA40_RS00670	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSA40_RS00685	COG0095	Lipoate-protein ligase
FSA40_RS00690	COG1473	amidohydrolase
FSA40_RS00695	COG2814	Major facilitator Superfamily
FSA40_RS00700	COG1309	transcriptional regulator
FSA40_RS00705	COG0583	DNA-binding transcription factor activity
FSA40_RS00715	COG0281	malic enzyme
FSA40_RS00720	COG0679	Auxin Efflux Carrier
FSA40_RS00725	COG2140	Oxalate decarboxylase
FSA40_RS00740	COG0242	peptide deformylase activity
FSA40_RS00745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSA40_RS00755	COG1012	belongs to the aldehyde dehydrogenase family
FSA40_RS00755	COG1454	alcohol dehydrogenase
FSA40_RS00785	COG1733	regulation of RNA biosynthetic process
FSA40_RS00790	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSA40_RS00795	COG1185	polyribonucleotide nucleotidyltransferase activity
FSA40_RS00805	COG1045	serine acetyltransferase
FSA40_RS00810	COG0215	cysteine-tRNA ligase activity
FSA40_RS00815	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FSA40_RS00820	COG5504	Zn-dependent protease
FSA40_RS00840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSA40_RS00860	COG1476	TRANSCRIPTIONal
FSA40_RS00870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FSA40_RS00875	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSA40_RS00880	COG4974	Belongs to the 'phage' integrase family
FSA40_RS00950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA40_RS00960	COG3976	FMN-binding domain protein
FSA40_RS00960	COG1053	succinate dehydrogenase
FSA40_RS00960	COG0431	NADPH-dependent FMN reductase
FSA40_RS00965	COG0431	NADPH-dependent FMN reductase
FSA40_RS00965	COG3976	FMN-binding domain protein
FSA40_RS00965	COG1053	succinate dehydrogenase
FSA40_RS00970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FSA40_RS00985	COG0803	Belongs to the bacterial solute-binding protein 9 family
FSA40_RS01000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSA40_RS01005	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FSA40_RS01095	COG0582	viral genome integration into host DNA
FSA40_RS01135	COG1461	Dihydroxyacetone kinase
FSA40_RS01140	COG0028	Belongs to the TPP enzyme family
FSA40_RS01145	COG0440	acetolactate synthase activity
FSA40_RS01150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FSA40_RS01155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FSA40_RS01165	COG1309	transcriptional regulator
FSA40_RS01175	COG1131	(ABC) transporter
FSA40_RS01185	COG1126	abc transporter atp-binding protein
FSA40_RS01190	COG0765	amino acid transport
FSA40_RS01200	COG1968	undecaprenyl-diphosphatase activity
FSA40_RS01205	COG4862	establishment of competence for transformation
FSA40_RS01210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSA40_RS01220	COG0719	Fe-S assembly protein
FSA40_RS01225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FSA40_RS01235	COG0719	Fe-S assembly protein
FSA40_RS01250	COG4166	transmembrane transport
FSA40_RS01255	COG0601	transmembrane transport
FSA40_RS01260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSA40_RS01265	COG0444	Belongs to the ABC transporter superfamily
FSA40_RS01270	COG4608	Belongs to the ABC transporter superfamily
FSA40_RS01285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FSA40_RS01290	COG0531	amino acid
FSA40_RS01295	COG2957	Belongs to the agmatine deiminase family
FSA40_RS01305	COG2918	glutathione biosynthetic process
FSA40_RS01305	COG1181	Belongs to the D-alanine--D-alanine ligase family
FSA40_RS01310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSA40_RS01325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA40_RS01335	COG3623	hexulose-6-phosphate isomerase
FSA40_RS01395	COG2274	protein secretion by the type I secretion system
FSA40_RS01415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FSA40_RS01445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FSA40_RS01445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FSA40_RS01450	COG1832	CoA-binding protein
FSA40_RS01460	COG0343	queuine tRNA-ribosyltransferase activity
FSA40_RS01475	COG1234	tRNA 3'-trailer cleavage
FSA40_RS01505	COG0166	Belongs to the GPI family
FSA40_RS01515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA40_RS01515	COG3711	transcriptional antiterminator
FSA40_RS01525	COG3730	PTS system glucitol sorbitol-specific
FSA40_RS01530	COG3732	PTS system glucitol sorbitol-specific
FSA40_RS01545	COG2171	N-acyltransferase activity
FSA40_RS01550	COG1473	amidohydrolase
FSA40_RS01555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSA40_RS01560	COG0457	Tetratricopeptide repeat
FSA40_RS01560	COG0705	Rhomboid family
FSA40_RS01565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FSA40_RS01570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FSA40_RS01575	COG0756	dUTP diphosphatase activity
FSA40_RS01600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSA40_RS01605	COG1827	regulation of RNA biosynthetic process
FSA40_RS01620	COG0137	argininosuccinate synthase activity
FSA40_RS01625	COG0165	Argininosuccinate lyase
FSA40_RS01630	COG0594	ribonuclease P activity
FSA40_RS01635	COG0706	membrane insertase activity
FSA40_RS01650	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FSA40_RS01655	COG0084	hydrolase, TatD family'
FSA40_RS01690	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSA40_RS01710	COG1162	GTPase activity
FSA40_RS01735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSA40_RS01745	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSA40_RS01750	COG0049	tRNA binding
FSA40_RS01755	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FSA40_RS01765	COG0126	phosphoglycerate kinase activity
FSA40_RS01775	COG0789	Transcriptional regulator
FSA40_RS01780	COG0174	glutamine synthetase
FSA40_RS01785	COG0069	glutamate synthase activity
FSA40_RS01785	COG0070	glutamate synthase
FSA40_RS01785	COG0067	glutamate synthase
FSA40_RS01790	COG0493	'glutamate synthase
FSA40_RS01795	COG3942	CHAP domain
FSA40_RS01805	COG5503	Protein of unknown function (DUF1447)
FSA40_RS01825	COG2226	methyltransferase
FSA40_RS01840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FSA40_RS01860	COG0667	Aldo Keto reductase
FSA40_RS01865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSA40_RS01875	COG1214	PFAM Peptidase M22, glycoprotease
FSA40_RS01880	COG0456	acetyltransferase
FSA40_RS01885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FSA40_RS01905	COG2081	HI0933 family
FSA40_RS01915	COG0778	Nitroreductase
FSA40_RS01920	COG1733	regulation of RNA biosynthetic process
FSA40_RS01925	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FSA40_RS01930	COG2936	dipeptidyl-peptidase activity
FSA40_RS01945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FSA40_RS01955	COG1882	Formate acetyltransferase
FSA40_RS01960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSA40_RS01975	COG0561	phosphatase activity
FSA40_RS01985	COG2252	PERMEase
FSA40_RS01990	COG0802	atpase or kinase
FSA40_RS01995	COG1316	TRANSCRIPTIONal
FSA40_RS02005	COG0537	adenosine 5'-monophosphoramidase activity
FSA40_RS02010	COG1131	(ABC) transporter
FSA40_RS02015	COG4473	ABC transporter
FSA40_RS02025	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FSA40_RS02035	COG0779	Required for maturation of 30S ribosomal subunits
FSA40_RS02040	COG0195	Participates in both transcription termination and antitermination
FSA40_RS02045	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FSA40_RS02055	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FSA40_RS02060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSA40_RS02075	COG2217	Heavy metal translocating P-type atpase
FSA40_RS02085	COG0561	phosphatase activity
FSA40_RS02095	COG1131	(ABC) transporter
FSA40_RS02125	COG1924	4 iron, 4 sulfur cluster binding
FSA40_RS02145	COG1673	EVE domain
FSA40_RS02155	COG0752	glycyl-tRNA synthetase alpha subunit
FSA40_RS02160	COG0751	glycine-tRNA ligase activity
FSA40_RS02165	COG4224	UPF0291 protein
FSA40_RS02175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FSA40_RS02180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FSA40_RS02190	COG0275	rRNA processing
FSA40_RS02195	COG4839	cell division protein FtsL
FSA40_RS02200	COG0768	penicillin binding
FSA40_RS02205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSA40_RS02215	COG0513	Belongs to the DEAD box helicase family
FSA40_RS02230	COG1126	abc transporter atp-binding protein
FSA40_RS02240	COG0492	ferredoxin-NADP+ reductase activity
FSA40_RS02245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FSA40_RS02250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSA40_RS02260	COG3579	cysteine-type endopeptidase activity
FSA40_RS02265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSA40_RS02270	COG3331	DNA recombination
FSA40_RS02275	COG4474	Belongs to the UPF0398 family
FSA40_RS02280	COG3599	regulation of cell shape
FSA40_RS02290	COG0116	Belongs to the methyltransferase superfamily
FSA40_RS02300	COG1854	S-ribosylhomocysteine lyase activity
FSA40_RS02305	COG4372	Transposase
FSA40_RS02305	COG1418	mRNA catabolic process
FSA40_RS02310	COG0194	GDP metabolic process
FSA40_RS02315	COG1758	RNA polymerase activity
FSA40_RS02320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSA40_RS02325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FSA40_RS02330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSA40_RS02330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSA40_RS02350	COG4585	Histidine kinase
FSA40_RS02355	COG2197	response regulator
FSA40_RS02365	COG1098	S1 RNA binding domain
FSA40_RS02370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FSA40_RS02375	COG1349	DNA-binding transcription factor activity
FSA40_RS02380	COG1882	Formate acetyltransferase
FSA40_RS02400	COG1739	Uncharacterized protein family UPF0029
FSA40_RS02405	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FSA40_RS02410	COG1040	competence protein
FSA40_RS02455	COG1349	DNA-binding transcription factor activity
FSA40_RS02460	COG0561	phosphatase activity
FSA40_RS02470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA40_RS02505	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FSA40_RS02525	COG4716	Myosin-crossreactive antigen
FSA40_RS02530	COG0742	ribosomal rna small subunit methyltransferase
FSA40_RS02535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FSA40_RS02540	COG3480	Lon protease (S16) C-terminal proteolytic domain
FSA40_RS02545	COG0737	Belongs to the 5'-nucleotidase family
FSA40_RS02550	COG4470	Protein conserved in bacteria
FSA40_RS02555	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FSA40_RS02565	COG1132	(ABC) transporter
FSA40_RS02570	COG1132	(ABC) transporter
FSA40_RS02580	COG3804	dihydrodipicolinate reductase
FSA40_RS02600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FSA40_RS02605	COG0512	Glutamine amidotransferase of anthranilate synthase
FSA40_RS02615	COG0134	indole-3-glycerol-phosphate synthase activity
FSA40_RS02620	COG0135	phosphoribosylanthranilate isomerase activity
FSA40_RS02625	COG0133	tryptophan synthase activity
FSA40_RS02630	COG0159	tryptophan synthase activity
FSA40_RS02640	COG0783	Belongs to the Dps family
FSA40_RS02650	COG1940	carbohydrate kinase activity
FSA40_RS02655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FSA40_RS02665	COG1217	gtp-binding protein TYPA
FSA40_RS02675	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FSA40_RS02680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FSA40_RS02690	COG0849	cell division
FSA40_RS02700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FSA40_RS02705	COG1799	cell septum assembly
FSA40_RS02715	COG2302	S4 RNA-binding domain
FSA40_RS02720	COG3599	regulation of cell shape
FSA40_RS02725	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSA40_RS02740	COG0542	response to heat
FSA40_RS02745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FSA40_RS02750	COG4703	Protein of unknown function (DUF1797)
FSA40_RS02755	COG0765	amino acid transport
FSA40_RS02760	COG1126	abc transporter atp-binding protein
FSA40_RS02780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSA40_RS02785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSA40_RS02790	COG1346	cytolysis
FSA40_RS02795	COG1380	Effector of murein hydrolase LrgA
FSA40_RS02800	COG3279	Response regulator of the LytR AlgR family
FSA40_RS02805	COG3275	phosphorelay sensor kinase activity
FSA40_RS02810	COG1570	exodeoxyribonuclease VII activity
FSA40_RS02815	COG1722	exodeoxyribonuclease VII activity
FSA40_RS02825	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FSA40_RS02830	COG1438	arginine binding
FSA40_RS02835	COG0497	DNA recombination
FSA40_RS02840	COG1307	EDD domain protein, DegV family
FSA40_RS02845	COG2755	lipolytic protein G-D-S-L family
FSA40_RS02855	COG0776	regulation of translation
FSA40_RS02860	COG2801	Transposase and inactivated derivatives
FSA40_RS02875	COG0735	belongs to the Fur family
FSA40_RS02890	COG0588	phosphoglycerate mutase activity
FSA40_RS02895	COG0768	penicillin binding
FSA40_RS02900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSA40_RS02905	COG1181	Belongs to the D-alanine--D-alanine ligase family
FSA40_RS02915	COG0385	Bile acid
FSA40_RS02920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSA40_RS02940	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FSA40_RS02950	COG3064	Membrane
FSA40_RS02950	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FSA40_RS02955	COG0513	Belongs to the DEAD box helicase family
FSA40_RS02975	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FSA40_RS02985	COG0726	polysaccharide deacetylase
FSA40_RS02990	COG0204	Acyl-transferase
FSA40_RS02995	COG1596	polysaccharide export
FSA40_RS02995	COG1555	photosystem II stabilization
FSA40_RS03000	COG2333	competence protein COMEC
FSA40_RS03000	COG0658	competence protein
FSA40_RS03015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSA40_RS03040	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSA40_RS03050	COG0363	glucosamine-6-phosphate deaminase activity
FSA40_RS03060	COG1187	pseudouridine synthase activity
FSA40_RS03070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSA40_RS03075	COG3321	synthase
FSA40_RS03075	COG1028	Short-chain dehydrogenase reductase Sdr
FSA40_RS03075	COG0604	alcohol dehydrogenase
FSA40_RS03105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FSA40_RS03105	COG0131	Imidazoleglycerol-phosphate dehydratase
FSA40_RS03110	COG4122	O-methyltransferase activity
FSA40_RS03115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSA40_RS03125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FSA40_RS03145	COG1131	(ABC) transporter
FSA40_RS03185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FSA40_RS03190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSA40_RS03195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSA40_RS03200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSA40_RS03210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSA40_RS03215	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FSA40_RS03220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FSA40_RS03225	COG0372	Belongs to the citrate synthase family
FSA40_RS03230	COG0538	isocitrate dehydrogenase activity
FSA40_RS03245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA40_RS03250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FSA40_RS03255	COG1012	belongs to the aldehyde dehydrogenase family
FSA40_RS03260	COG0789	Transcriptional regulator
FSA40_RS03270	COG0656	L-ascorbic acid biosynthetic process
FSA40_RS03295	COG2195	Cleaves the N-terminal amino acid of tripeptides
FSA40_RS03315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FSA40_RS03320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FSA40_RS03325	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FSA40_RS03330	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FSA40_RS03335	COG0588	phosphoglycerate mutase activity
FSA40_RS03345	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FSA40_RS03360	COG3859	Proton-coupled thiamine transporter YuaJ
FSA40_RS03390	COG0772	Belongs to the SEDS family
FSA40_RS03395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSA40_RS03400	COG0149	triose-phosphate isomerase activity
FSA40_RS03420	COG1078	dGTPase activity
FSA40_RS03445	COG0584	glycerophosphoryl diester phosphodiesterase
FSA40_RS03460	COG0604	alcohol dehydrogenase
FSA40_RS03470	COG1131	(ABC) transporter
FSA40_RS03520	COG0561	phosphatase activity
FSA40_RS03525	COG0561	phosphatase activity
FSA40_RS03530	COG0552	protein localization to endoplasmic reticulum
FSA40_RS03535	COG0477	Major facilitator Superfamily
FSA40_RS03540	COG3689	TIGRFAM TIGR03943 family protein
FSA40_RS03545	COG0701	Predicted permease
FSA40_RS03560	COG2183	response to ionizing radiation
FSA40_RS03565	COG3091	SprT-like family
FSA40_RS03575	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FSA40_RS03580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FSA40_RS03605	COG0826	peptidase U32
FSA40_RS03610	COG0450	alkyl hydroperoxide reductase
FSA40_RS03625	COG4443	Transcriptional Coactivator p15 (PC4)
FSA40_RS03630	COG1914	H( )-stimulated, divalent metal cation uptake system
FSA40_RS03640	COG0366	Alpha amylase catalytic
FSA40_RS03640	COG5263	repeat protein
FSA40_RS03645	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FSA40_RS03665	COG1368	sulfuric ester hydrolase activity
FSA40_RS03670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FSA40_RS03675	COG0710	3-dehydroquinate dehydratase activity
FSA40_RS03680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FSA40_RS03685	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FSA40_RS03690	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FSA40_RS03695	COG0287	Prephenate dehydrogenase
FSA40_RS03700	COG3679	Belongs to the UPF0342 family
FSA40_RS03705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSA40_RS03710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FSA40_RS03715	COG0077	Prephenate dehydratase
FSA40_RS03725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FSA40_RS03785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FSA40_RS03795	COG0488	(ABC) transporter
FSA40_RS03805	COG1126	abc transporter atp-binding protein
FSA40_RS03820	COG0556	nucleotide-excision repair
FSA40_RS03840	COG1051	belongs to the nudix hydrolase family
FSA40_RS03845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA40_RS03855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA40_RS03865	COG1970	mechanosensitive ion channel activity
FSA40_RS03875	COG0358	DNA primase activity
FSA40_RS03880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSA40_RS03885	COG2151	metal-sulfur cluster biosynthetic enzyme
FSA40_RS03890	COG1091	dTDP-4-dehydrorhamnose reductase activity
FSA40_RS03925	COG1368	sulfuric ester hydrolase activity
FSA40_RS03935	COG0463	Glycosyl transferase, family 2
FSA40_RS03950	COG3942	CHAP domain
FSA40_RS03955	COG0656	L-ascorbic acid biosynthetic process
FSA40_RS03960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSA40_RS03965	COG0285	dihydrofolate synthase activity
FSA40_RS03975	COG1104	cysteine desulfurase activity
FSA40_RS03980	COG0301	tRNA thio-modification
FSA40_RS04000	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FSA40_RS04010	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FSA40_RS04020	COG2816	NAD+ diphosphatase activity
FSA40_RS04025	COG0583	DNA-binding transcription factor activity
FSA40_RS04030	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FSA40_RS04035	COG0564	pseudouridine synthase activity
FSA40_RS04045	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FSA40_RS04055	COG0540	Belongs to the ATCase OTCase family
FSA40_RS04060	COG0505	Belongs to the CarA family
FSA40_RS04065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSA40_RS04075	COG1136	(ABC) transporter
FSA40_RS04080	COG0577	efflux transmembrane transporter activity
FSA40_RS04085	COG0228	four-way junction DNA binding
FSA40_RS04090	COG1837	Belongs to the UPF0109 family
FSA40_RS04095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSA40_RS04100	COG0336	Belongs to the RNA methyltransferase TrmD family
FSA40_RS04105	COG0492	ferredoxin-NADP+ reductase activity
FSA40_RS04110	COG1349	DNA-binding transcription factor activity
FSA40_RS04115	COG1105	Belongs to the carbohydrate kinase PfkB family
FSA40_RS04120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA40_RS04120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FSA40_RS04120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FSA40_RS04125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FSA40_RS04130	COG0646	methionine synthase
FSA40_RS04130	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FSA40_RS04135	COG2801	Transposase and inactivated derivatives
FSA40_RS04145	COG2207	Transcriptional regulator
FSA40_RS04150	COG3345	alpha-galactosidase
FSA40_RS04155	COG1653	transport
FSA40_RS04160	COG1175	transmembrane transport
FSA40_RS04165	COG0395	ABC-type sugar transport system, permease component
FSA40_RS04170	COG0366	Alpha amylase catalytic
FSA40_RS04175	COG3842	ATPase activity
FSA40_RS04180	COG0366	Alpha amylase catalytic
FSA40_RS04190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FSA40_RS04195	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FSA40_RS04200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSA40_RS04220	COG1131	(ABC) transporter
FSA40_RS04235	COG1307	EDD domain protein, DegV family
FSA40_RS04240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FSA40_RS04245	COG0617	tRNA 3'-terminal CCA addition
FSA40_RS04250	COG0488	(ABC) transporter
FSA40_RS04260	COG1132	(ABC) transporter
FSA40_RS04270	COG0366	Alpha amylase catalytic
FSA40_RS04270	COG5263	repeat protein
FSA40_RS04280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSA40_RS04290	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FSA40_RS04305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FSA40_RS04320	COG1132	(ABC) transporter
FSA40_RS04325	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FSA40_RS04335	COG2357	RelA SpoT domain protein
FSA40_RS04340	COG0745	RESPONSE REGULATOR receiver
FSA40_RS04350	COG3759	membrane
FSA40_RS04355	COG0583	DNA-binding transcription factor activity
FSA40_RS04365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA40_RS04370	COG0765	amino acid transport
FSA40_RS04375	COG0765	amino acid transport
FSA40_RS04380	COG1126	abc transporter atp-binding protein
FSA40_RS04395	COG1304	FMN binding
FSA40_RS04400	COG1272	protein, Hemolysin III
FSA40_RS04415	COG3425	synthase
FSA40_RS04420	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FSA40_RS04425	COG3201	nicotinamide mononucleotide transporter
FSA40_RS04430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FSA40_RS04440	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FSA40_RS04445	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FSA40_RS04450	COG0833	amino acid
FSA40_RS04455	COG2040	homocysteine
FSA40_RS04460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSA40_RS04485	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FSA40_RS04490	COG0222	ribosome binding
FSA40_RS04500	COG1960	acyl-CoA dehydrogenase activity
FSA40_RS04505	COG0726	polysaccharide deacetylase
FSA40_RS04515	COG0083	homoserine kinase activity
FSA40_RS04520	COG0285	dihydrofolate synthase activity
FSA40_RS04525	COG0302	gtp cyclohydrolase
FSA40_RS04545	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FSA40_RS04550	COG3842	ATPase activity
FSA40_RS04555	COG1176	ABC-type spermidine putrescine transport system, permease component I
FSA40_RS04560	COG1177	transmembrane transport
FSA40_RS04565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FSA40_RS04570	COG3711	transcriptional antiterminator
FSA40_RS04575	COG2190	(PTS) system
FSA40_RS04575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FSA40_RS04575	COG1263	PTS System
FSA40_RS04605	COG4932	domain protein
FSA40_RS04610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSA40_RS04620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FSA40_RS04625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSA40_RS04640	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FSA40_RS04645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSA40_RS04650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FSA40_RS04655	COG4605	iron ion homeostasis
FSA40_RS04660	COG4604	ABC transporter, ATP-binding protein
FSA40_RS04665	COG4607	ABC-type enterochelin transport system periplasmic component
FSA40_RS04680	COG0758	DNA mediated transformation
FSA40_RS04685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FSA40_RS04690	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FSA40_RS04695	COG0366	Alpha amylase catalytic
FSA40_RS04695	COG5263	repeat protein
FSA40_RS04700	COG5263	repeat protein
FSA40_RS04700	COG0366	Alpha amylase catalytic
FSA40_RS04715	COG0745	RESPONSE REGULATOR receiver
FSA40_RS04730	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FSA40_RS04740	COG2851	Citrate transporter
FSA40_RS04750	COG0511	ligase activity, forming carbon-carbon bonds
FSA40_RS04755	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FSA40_RS04760	COG3052	prosthetic group binding
FSA40_RS04790	COG4974	Belongs to the 'phage' integrase family
FSA40_RS04795	COG1131	(ABC) transporter
FSA40_RS04805	COG5002	protein histidine kinase activity
FSA40_RS04810	COG0745	RESPONSE REGULATOR receiver
FSA40_RS04815	COG1442	glycosyl transferase family 8
FSA40_RS04820	COG4221	oxidoreductase activity
FSA40_RS04825	COG1131	(ABC) transporter
FSA40_RS04835	COG0280	phosphate acetyltransferase
FSA40_RS04840	COG0564	pseudouridine synthase activity
FSA40_RS04845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSA40_RS04850	COG2357	RelA SpoT domain protein
FSA40_RS04865	COG4116	CYTH
FSA40_RS04870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSA40_RS04875	COG1104	cysteine desulfurase activity
FSA40_RS04885	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FSA40_RS04890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FSA40_RS04920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSA40_RS04925	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FSA40_RS04935	COG4175	Glycine betaine
FSA40_RS04935	COG3448	diguanylate cyclase activity
FSA40_RS04945	COG2188	Transcriptional regulator
FSA40_RS04950	COG0519	Catalyzes the synthesis of GMP from XMP
FSA40_RS04960	COG1131	(ABC) transporter
FSA40_RS04980	COG1247	-acetyltransferase
FSA40_RS04985	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FSA40_RS04995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FSA40_RS05000	COG4684	Psort location CytoplasmicMembrane, score
FSA40_RS05005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSA40_RS05010	COG1132	(ABC) transporter
FSA40_RS05015	COG1132	(ABC) transporter
FSA40_RS05030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FSA40_RS05035	COG0009	L-threonylcarbamoyladenylate synthase
FSA40_RS05040	COG2890	protein-(glutamine-N5) methyltransferase activity
FSA40_RS05045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSA40_RS05050	COG1435	thymidine kinase activity
FSA40_RS05055	COG1942	4-Oxalocrotonate Tautomerase
FSA40_RS05070	COG1053	succinate dehydrogenase
FSA40_RS05070	COG0431	NADPH-dependent FMN reductase
FSA40_RS05070	COG3976	FMN-binding domain protein
FSA40_RS05080	COG0577	efflux transmembrane transporter activity
FSA40_RS05085	COG1136	(ABC) transporter
FSA40_RS05090	COG1174	glycine betaine transport
FSA40_RS05105	COG1063	alcohol dehydrogenase
FSA40_RS05110	COG0628	permease
FSA40_RS05115	COG2723	6-phospho-beta-galactosidase activity
FSA40_RS05125	COG0406	alpha-ribazole phosphatase activity
FSA40_RS05135	COG0346	lactoylglutathione lyase activity
FSA40_RS05145	COG0561	phosphatase activity
FSA40_RS05160	COG0346	lactoylglutathione lyase activity
FSA40_RS05165	COG3764	Sortase (surface protein transpeptidase)
FSA40_RS05175	COG0039	L-malate dehydrogenase activity
FSA40_RS05190	COG1079	Belongs to the binding-protein-dependent transport system permease family
FSA40_RS05195	COG4603	Belongs to the binding-protein-dependent transport system permease family
FSA40_RS05200	COG3845	ABC transporter
FSA40_RS05205	COG1744	ABC transporter substrate-binding protein PnrA-like
FSA40_RS05210	COG0295	cytidine deaminase activity
FSA40_RS05215	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FSA40_RS05225	COG2813	Specifically methylates the guanine in position
FSA40_RS05230	COG1072	(Pantothenic acid kinase))
FSA40_RS05235	COG0268	Binds directly to 16S ribosomal RNA
FSA40_RS05240	COG5002	protein histidine kinase activity
FSA40_RS05245	COG0745	RESPONSE REGULATOR receiver
FSA40_RS05260	COG0704	Plays a role in the regulation of phosphate uptake
FSA40_RS05265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSA40_RS05270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSA40_RS05275	COG0581	inorganic phosphate transmembrane transporter activity
FSA40_RS05280	COG0573	inorganic phosphate transmembrane transporter activity
FSA40_RS05290	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FSA40_RS05290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSA40_RS05295	COG0483	inositol monophosphate 1-phosphatase activity
FSA40_RS05300	COG4476	Belongs to the UPF0223 family
FSA40_RS05305	COG1393	Belongs to the ArsC family
FSA40_RS05310	COG0196	riboflavin kinase activity
FSA40_RS05315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSA40_RS05320	COG2205	protein histidine kinase activity
FSA40_RS05325	COG0745	RESPONSE REGULATOR receiver
FSA40_RS05410	COG1132	(ABC) transporter
FSA40_RS05440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSA40_RS05445	COG0785	Cytochrome C biogenesis protein
FSA40_RS05460	COG2873	o-acetylhomoserine
FSA40_RS05465	COG0210	DNA helicase
FSA40_RS05470	COG1115	amino acid carrier protein
FSA40_RS05475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FSA40_RS05480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA40_RS05485	COG1126	abc transporter atp-binding protein
FSA40_RS05490	COG0765	amino acid transport
FSA40_RS05495	COG2824	Alkylphosphonate utilization operon protein PhnA
FSA40_RS05500	COG0246	Mannitol dehydrogenase
FSA40_RS05505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA40_RS05510	COG3711	transcriptional antiterminator
FSA40_RS05515	COG2213	PTS system mannitol-specific
FSA40_RS05520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSA40_RS05530	COG2261	transglycosylase associated protein
FSA40_RS05535	COG0469	pyruvate kinase activity
FSA40_RS05540	COG0205	6-phosphofructokinase activity
FSA40_RS05550	COG1725	Transcriptional regulator
FSA40_RS05555	COG1131	(ABC) transporter
FSA40_RS05585	COG0539	negative regulation of cytoplasmic translation
FSA40_RS05605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FSA40_RS05620	COG0187	DNA topoisomerase II activity
FSA40_RS05625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FSA40_RS05640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FSA40_RS05645	COG0765	amino acid transport
FSA40_RS05650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA40_RS05660	COG2315	Protein conserved in bacteria
FSA40_RS05665	COG1881	PFAM PEBP family protein
FSA40_RS05675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FSA40_RS05685	COG0167	dihydroorotate dehydrogenase activity
FSA40_RS05690	COG0543	2 iron, 2 sulfur cluster binding
FSA40_RS05705	COG0813	purine-nucleoside phosphorylase activity
FSA40_RS05735	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FSA40_RS05740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FSA40_RS05745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FSA40_RS05765	COG1573	uracil-dna glycosylase
FSA40_RS05770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FSA40_RS05780	COG0322	excinuclease ABC activity
FSA40_RS05790	COG1011	Hydrolase
FSA40_RS05800	COG0148	phosphopyruvate hydratase activity
FSA40_RS05870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSA40_RS05880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FSA40_RS05885	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSA40_RS05895	COG0131	Imidazoleglycerol-phosphate dehydratase
FSA40_RS05900	COG0560	Phosphoserine phosphatase
FSA40_RS05905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSA40_RS05910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSA40_RS05915	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FSA40_RS05920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSA40_RS05930	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FSA40_RS05945	COG0772	Belongs to the SEDS family
FSA40_RS05970	COG2814	Major facilitator Superfamily
FSA40_RS05980	COG0335	large ribosomal subunit rRNA binding
FSA40_RS05985	COG0038	chloride channel
FSA40_RS05990	COG0038	chloride channel
FSA40_RS05995	COG1605	Chorismate mutase
FSA40_RS05995	COG0077	Prephenate dehydratase
FSA40_RS06010	COG0716	FMN binding
FSA40_RS06015	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSA40_RS06025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSA40_RS06030	COG0254	rRNA binding
FSA40_RS06045	COG2226	methyltransferase
FSA40_RS06060	COG1481	regulation of sporulation
FSA40_RS06070	COG1660	Displays ATPase and GTPase activities
FSA40_RS06080	COG0251	oxidation-reduction process
FSA40_RS06085	COG0371	Dehydrogenase
FSA40_RS06095	COG0017	Asparaginyl-tRNA synthetase
FSA40_RS06100	COG0436	Aminotransferase
FSA40_RS06105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FSA40_RS06105	COG1199	ATP-dependent helicase activity
FSA40_RS06115	COG1122	ATPase activity
FSA40_RS06160	COG2177	Part of the ABC transporter FtsEX involved in
FSA40_RS06165	COG2884	Cell division ATP-binding protein ftsE
FSA40_RS06175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FSA40_RS06265	COG1136	(ABC) transporter
FSA40_RS06300	COG1309	transcriptional regulator
FSA40_RS06320	COG1136	(ABC) transporter
FSA40_RS06325	COG2226	methyltransferase
FSA40_RS06340	COG2801	Transposase and inactivated derivatives
FSA40_RS06360	COG0456	acetyltransferase
FSA40_RS06360	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FSA40_RS06375	COG0066	3-isopropylmalate dehydratase activity
FSA40_RS06380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSA40_RS06385	COG0473	3-isopropylmalate dehydrogenase activity
FSA40_RS06395	COG0572	uridine kinase
FSA40_RS06400	COG0673	inositol 2-dehydrogenase activity
FSA40_RS06410	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FSA40_RS06435	COG0481	GTPase activity
FSA40_RS06460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSA40_RS06475	COG1518	maintenance of DNA repeat elements
FSA40_RS06495	COG1053	succinate dehydrogenase
FSA40_RS06495	COG3976	FMN-binding domain protein
FSA40_RS06505	COG0577	efflux transmembrane transporter activity
FSA40_RS06505	COG1136	(ABC) transporter
FSA40_RS06515	COG0647	UMP catabolic process
FSA40_RS06520	COG1051	belongs to the nudix hydrolase family
FSA40_RS06530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSA40_RS06540	COG2249	NAD(P)H dehydrogenase (quinone) activity
FSA40_RS06545	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSA40_RS06550	COG0022	dehydrogenase e1 component
FSA40_RS06555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSA40_RS06565	COG0542	response to heat
FSA40_RS06570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSA40_RS06580	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FSA40_RS06585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSA40_RS06590	COG3442	glutamine amidotransferase
FSA40_RS06595	COG0488	(ABC) transporter
FSA40_RS06605	COG1215	transferase activity, transferring glycosyl groups
FSA40_RS06620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FSA40_RS06630	COG4808	Protein conserved in bacteria
FSA40_RS06655	COG3842	ATPase activity
FSA40_RS06670	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FSA40_RS06675	COG1113	amino acid transport
FSA40_RS06680	COG3527	Alpha-acetolactate decarboxylase
FSA40_RS06685	COG0028	Belongs to the TPP enzyme family
FSA40_RS06695	COG0628	permease
FSA40_RS06700	COG1051	belongs to the nudix hydrolase family
FSA40_RS06710	COG1088	dTDP-glucose 4,6-dehydratase activity
FSA40_RS06725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FSA40_RS06730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSA40_RS06740	COG2384	SAM-dependent methyltransferase
FSA40_RS06750	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FSA40_RS06755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSA40_RS06770	COG2378	regulation of single-species biofilm formation
FSA40_RS06775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FSA40_RS06775	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FSA40_RS06780	COG0300	oxidoreductase activity
FSA40_RS06785	COG1234	tRNA 3'-trailer cleavage
FSA40_RS06795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSA40_RS06800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FSA40_RS06830	COG1401	restriction endodeoxyribonuclease activity
FSA40_RS06860	COG2723	6-phospho-beta-galactosidase activity
FSA40_RS06865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA40_RS06865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA40_RS06870	COG1447	Phosphotransferase system cellobiose-specific component IIA
FSA40_RS06875	COG3775	system Galactitol-specific IIC component
FSA40_RS06890	COG3684	Belongs to the aldolase LacD family
FSA40_RS06895	COG1105	Belongs to the carbohydrate kinase PfkB family
FSA40_RS06900	COG0698	ribose 5-phosphate isomerase
FSA40_RS06905	COG0698	ribose 5-phosphate isomerase
FSA40_RS06910	COG1349	DNA-binding transcription factor activity
FSA40_RS06930	COG1518	maintenance of DNA repeat elements
FSA40_RS06945	COG1857	crispr-associated protein
FSA40_RS06980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA40_RS06980	COG0072	phenylalanine-tRNA ligase activity
FSA40_RS06995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSA40_RS07000	COG1396	sequence-specific DNA binding
FSA40_RS07005	COG0072	phenylalanine-tRNA ligase activity
FSA40_RS07005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA40_RS07015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FSA40_RS07020	COG1196	nuclear chromosome segregation
FSA40_RS07025	COG0571	ribonuclease III activity
FSA40_RS07030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FSA40_RS07035	COG5002	protein histidine kinase activity
FSA40_RS07040	COG0745	RESPONSE REGULATOR receiver
FSA40_RS07045	COG1126	abc transporter atp-binding protein
FSA40_RS07050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA40_RS07055	COG0765	amino acid transport
FSA40_RS07060	COG0765	amino acid transport
FSA40_RS07075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FSA40_RS07085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FSA40_RS07090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSA40_RS07095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FSA40_RS07100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FSA40_RS07105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FSA40_RS07110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FSA40_RS07115	COG0356	it plays a direct role in the translocation of protons across the membrane
FSA40_RS07125	COG0058	SHG alpha-glucan phosphorylase activity
FSA40_RS07130	COG0297	glycogen (starch) synthase activity
FSA40_RS07135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FSA40_RS07140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FSA40_RS07145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FSA40_RS07150	COG1523	belongs to the glycosyl hydrolase 13 family
FSA40_RS07155	COG1597	lipid kinase activity
FSA40_RS07160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSA40_RS07165	COG4708	membrane
FSA40_RS07180	COG2197	response regulator
FSA40_RS07185	COG4585	Histidine kinase
FSA40_RS07195	COG1131	(ABC) transporter
FSA40_RS07215	COG1295	ribonuclease BN
FSA40_RS07220	COG0024	Methionine aminopeptidase
FSA40_RS07225	COG4109	DRTGG domain
FSA40_RS07245	COG0569	domain protein
FSA40_RS07250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FSA40_RS07255	COG0058	SHG alpha-glucan phosphorylase activity
FSA40_RS07260	COG1640	4-alpha-glucanotransferase
FSA40_RS07265	COG1609	Transcriptional regulator
FSA40_RS07275	COG1175	transmembrane transport
FSA40_RS07280	COG3833	ABC-type maltose transport systems, permease component
FSA40_RS07285	COG3842	ATPase activity
FSA40_RS07290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FSA40_RS07295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSA40_RS07345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FSA40_RS07355	COG4716	Myosin-crossreactive antigen
FSA40_RS07365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FSA40_RS07395	COG1609	Transcriptional regulator
FSA40_RS07415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA40_RS07425	COG1447	Phosphotransferase system cellobiose-specific component IIA
FSA40_RS07430	COG3711	transcriptional antiterminator
FSA40_RS07430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA40_RS07435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA40_RS07440	COG2723	6-phospho-beta-galactosidase activity
FSA40_RS07450	COG0778	Nitroreductase
FSA40_RS07455	COG0346	lactoylglutathione lyase activity
FSA40_RS07460	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FSA40_RS07465	COG0557	exoribonuclease II activity
FSA40_RS07475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FSA40_RS07480	COG2814	Major facilitator Superfamily
FSA40_RS07485	COG0237	dephospho-CoA kinase activity
FSA40_RS07490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FSA40_RS07505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSA40_RS07510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FSA40_RS07515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FSA40_RS07520	COG1702	phosphate starvation-inducible protein PhoH
FSA40_RS07525	COG4479	Belongs to the UPF0346 family
FSA40_RS07530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSA40_RS07540	COG0233	cytoplasmic translational termination
FSA40_RS07545	COG0528	UMP kinase activity
FSA40_RS07550	COG0081	regulation of translation
FSA40_RS07555	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FSA40_RS07565	COG1674	ftsk spoiiie
FSA40_RS07590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FSA40_RS07605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA40_RS07605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA40_RS07645	COG0640	Transcriptional regulator
FSA40_RS07655	COG0708	Exodeoxyribonuclease III
FSA40_RS07660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FSA40_RS07665	COG1393	Belongs to the ArsC family
FSA40_RS07670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FSA40_RS07675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSA40_RS07690	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FSA40_RS07695	COG0347	Belongs to the P(II) protein family
FSA40_RS07700	COG0004	ammonium transporteR
FSA40_RS07710	COG4467	Involved in initiation control of chromosome replication
FSA40_RS07715	COG1774	PSP1 C-terminal conserved region
FSA40_RS07720	COG0470	DNA polymerase III
FSA40_RS07725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FSA40_RS07730	COG0517	IMP dehydrogenase activity
FSA40_RS07750	COG0559	Belongs to the binding-protein-dependent transport system permease family
FSA40_RS07760	COG4471	UPF0298 protein
FSA40_RS07770	COG0740	serine-type endopeptidase activity
FSA40_RS07775	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FSA40_RS07780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FSA40_RS07785	COG0626	cystathionine gamma-synthase activity
FSA40_RS07790	COG2244	polysaccharide biosynthetic process
FSA40_RS07795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSA40_RS07820	COG0693	protein deglycase activity
FSA40_RS07825	COG2378	regulation of single-species biofilm formation
FSA40_RS07835	COG1227	inorganic diphosphatase activity
FSA40_RS07840	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FSA40_RS07845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSA40_RS07850	COG1696	Membrane protein involved in D-alanine export
FSA40_RS07855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSA40_RS07865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FSA40_RS07870	COG1253	flavin adenine dinucleotide binding
FSA40_RS07875	COG0628	permease
FSA40_RS07880	COG1119	ATPase activity
FSA40_RS07885	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FSA40_RS07890	COG1242	4 iron, 4 sulfur cluster binding
FSA40_RS07895	COG1346	cytolysis
FSA40_RS07905	COG0671	phosphoesterase, PA-phosphatase related
FSA40_RS07910	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FSA40_RS07935	COG0569	domain protein
FSA40_RS07940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FSA40_RS07945	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSA40_RS07950	COG1187	pseudouridine synthase activity
FSA40_RS07955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSA40_RS07960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSA40_RS07965	COG0582	viral genome integration into host DNA
FSA40_RS07980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FSA40_RS07985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSA40_RS07990	COG3763	UPF0154 protein
FSA40_RS07995	COG0019	diaminopimelate decarboxylase activity
FSA40_RS08010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSA40_RS08015	COG1254	Belongs to the acylphosphatase family
FSA40_RS08020	COG0706	membrane insertase activity
FSA40_RS08025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSA40_RS08030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSA40_RS08040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSA40_RS08065	COG0439	Biotin carboxylase
FSA40_RS08070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FSA40_RS08080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSA40_RS08085	COG1028	Short-chain dehydrogenase reductase Sdr
FSA40_RS08090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FSA40_RS08105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSA40_RS08110	COG1846	Transcriptional regulator
FSA40_RS08115	COG1024	Enoyl-CoA hydratase
FSA40_RS08120	COG0546	phosphoglycolate phosphatase activity
FSA40_RS08210	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FSA40_RS08215	COG1518	maintenance of DNA repeat elements
FSA40_RS08265	COG0525	valine-tRNA ligase activity
FSA40_RS08315	COG1780	Probably involved in ribonucleotide reductase function
FSA40_RS08320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FSA40_RS08325	COG2137	regulation of response to DNA damage stimulus
FSA40_RS08390	COG0442	prolyl-tRNA aminoacylation
FSA40_RS08400	COG4589	Belongs to the CDS family
FSA40_RS08405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSA40_RS08410	COG1862	Preprotein translocase
FSA40_RS08420	COG0217	transcriptional regulatory protein
FSA40_RS08425	COG0789	Transcriptional regulator
FSA40_RS08430	COG1323	Belongs to the UPF0348 family
FSA40_RS08445	COG2226	methyltransferase
FSA40_RS08450	COG0799	negative regulation of ribosome biogenesis
FSA40_RS08455	COG1713	HD superfamily hydrolase involved in NAD metabolism
FSA40_RS08460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FSA40_RS08465	COG1534	Rna-binding protein
FSA40_RS08470	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FSA40_RS08475	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FSA40_RS08495	COG1819	glycosyl
FSA40_RS08500	COG0697	spore germination
FSA40_RS08505	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSA40_RS08510	COG0154	amidase activity
FSA40_RS08515	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSA40_RS08520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSA40_RS08525	COG1335	isochorismatase
FSA40_RS08530	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FSA40_RS08535	COG0436	Aminotransferase
FSA40_RS08540	COG1268	BioY protein
FSA40_RS08550	COG0561	phosphatase activity
FSA40_RS08555	COG0252	asparaginase activity
FSA40_RS08565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSA40_RS08570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSA40_RS08575	COG0736	holo-[acyl-carrier-protein] synthase activity
FSA40_RS08580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSA40_RS08585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSA40_RS08590	COG0653	protein targeting
FSA40_RS08595	COG1482	cell wall glycoprotein biosynthetic process
FSA40_RS08600	COG1940	carbohydrate kinase activity
FSA40_RS08605	COG2190	(PTS) system
FSA40_RS08605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FSA40_RS08605	COG1263	PTS System
FSA40_RS08610	COG1621	beta-fructofuranosidase activity
FSA40_RS08615	COG1609	Transcriptional regulator
FSA40_RS08620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSA40_RS08630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSA40_RS08635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSA40_RS08640	COG2131	deaminase
FSA40_RS08645	COG0006	proline dipeptidase activity
FSA40_RS08650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSA40_RS08685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FSA40_RS08690	COG0629	single-stranded DNA binding
FSA40_RS08695	COG0360	Binds together with S18 to 16S ribosomal RNA
FSA40_RS08710	COG1194	a g-specific adenine glycosylase
FSA40_RS08715	COG1063	alcohol dehydrogenase
FSA40_RS08720	COG3118	belongs to the thioredoxin family
FSA40_RS08725	COG1193	negative regulation of DNA recombination
FSA40_RS08740	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSA40_RS08745	COG0681	Belongs to the peptidase S26 family
FSA40_RS08750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSA40_RS08765	COG3715	PTS system
FSA40_RS08770	COG3716	PTS system mannose fructose sorbose family IID component
FSA40_RS08790	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSA40_RS08880	COG3290	protein histidine kinase activity
FSA40_RS08890	COG0586	Pfam SNARE associated Golgi protein
FSA40_RS08900	COG1160	GTP binding
FSA40_RS08905	COG1484	DNA-dependent DNA replication
FSA40_RS08915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FSA40_RS08955	COG1484	DNA-dependent DNA replication
FSA40_RS08965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FSA40_RS08970	COG0745	RESPONSE REGULATOR receiver
FSA40_RS08985	COG1136	(ABC) transporter
FSA40_RS08990	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSA40_RS08995	COG0501	Belongs to the peptidase M48B family
FSA40_RS09000	COG1704	LemA family
FSA40_RS09005	COG0357	Ribosomal RNA small subunit methyltransferase G
FSA40_RS09015	COG1122	ATPase activity
FSA40_RS09020	COG4720	Psort location CytoplasmicMembrane, score
FSA40_RS09030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSA40_RS09040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSA40_RS09045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FSA40_RS09050	COG1464	Belongs to the NlpA lipoprotein family
FSA40_RS09055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA40_RS09090	COG1131	(ABC) transporter
FSA40_RS09100	COG0495	leucyl-tRNA aminoacylation
FSA40_RS09130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSA40_RS09135	COG0564	pseudouridine synthase activity
FSA40_RS09145	COG0459	protein refolding
FSA40_RS09150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FSA40_RS09160	COG3716	PTS system mannose fructose sorbose family IID component
FSA40_RS09165	COG3715	PTS system
FSA40_RS09195	COG2197	response regulator
FSA40_RS09200	COG4585	Histidine kinase
FSA40_RS09220	COG1846	Transcriptional regulator
FSA40_RS09225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA40_RS09225	COG0072	phenylalanine-tRNA ligase activity
FSA40_RS09230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSA40_RS09240	COG1363	Peptidase, m42
FSA40_RS09245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FSA40_RS09265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSA40_RS09270	COG0827	DNA restriction-modification system
FSA40_RS09300	COG1459	type II secretion system
FSA40_RS09305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSA40_RS09315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSA40_RS09320	COG0085	RNA polymerase activity
FSA40_RS09325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSA40_RS09330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSA40_RS09335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSA40_RS09340	COG1121	(ABC) transporter
FSA40_RS09350	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FSA40_RS09390	COG0203	ribosomal protein L17
FSA40_RS09395	COG0202	RNA polymerase activity
FSA40_RS09400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FSA40_RS09405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FSA40_RS09415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FSA40_RS09420	COG0563	adenylate kinase activity
FSA40_RS09425	COG0201	protein transport
FSA40_RS09430	COG0200	Binds to the 23S rRNA
FSA40_RS09435	COG1841	ribosomal large subunit assembly
FSA40_RS09440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSA40_RS09450	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSA40_RS09455	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSA40_RS09460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FSA40_RS09465	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FSA40_RS09470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FSA40_RS09475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FSA40_RS09480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FSA40_RS09485	COG0255	Belongs to the universal ribosomal protein uL29 family
FSA40_RS09490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FSA40_RS09495	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FSA40_RS09500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FSA40_RS09510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FSA40_RS09515	COG0089	rRNA binding
FSA40_RS09525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FSA40_RS09530	COG0051	transcription antitermination factor activity, RNA binding
FSA40_RS09540	COG1621	beta-fructofuranosidase activity
FSA40_RS09545	COG0542	response to heat
FSA40_RS09550	COG4463	regulation of RNA biosynthetic process
FSA40_RS09555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FSA40_RS09560	COG0052	Belongs to the universal ribosomal protein uS2 family
FSA40_RS09575	COG1619	proteins homologs of microcin C7 resistance protein MccF
FSA40_RS09580	COG3590	peptidase
FSA40_RS09590	COG0366	Alpha amylase catalytic
FSA40_RS09595	COG1263	PTS System
FSA40_RS09595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FSA40_RS09600	COG2188	Transcriptional regulator
FSA40_RS09605	COG5297	Belongs to the glycosyl hydrolase family 6
FSA40_RS09610	COG1490	D-aminoacyl-tRNA deacylase activity
FSA40_RS09625	COG1263	PTS System
FSA40_RS09625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FSA40_RS09625	COG2190	(PTS) system
FSA40_RS09640	COG1609	Transcriptional regulator
FSA40_RS09645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSA40_RS09650	COG2264	protein methyltransferase activity
FSA40_RS09670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSA40_RS09685	COG2217	Heavy metal translocating P-type atpase
FSA40_RS09695	COG2855	membrane
FSA40_RS09700	COG0583	DNA-binding transcription factor activity
FSA40_RS09710	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FSA40_RS09720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSA40_RS09730	COG0463	Glycosyl transferase, family 2
FSA40_RS09735	COG0428	transporter
FSA40_RS09740	COG3022	response to hydroperoxide
FSA40_RS09775	COG3906	Belongs to the UPF0473 family
FSA40_RS09780	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSA40_RS09785	COG4472	Bacterial protein of unknown function (DUF965)
FSA40_RS09810	COG1393	Belongs to the ArsC family
FSA40_RS09815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FSA40_RS09820	COG1058	Belongs to the CinA family
FSA40_RS09820	COG1546	Belongs to the CinA family
FSA40_RS09825	COG0519	Catalyzes the synthesis of GMP from XMP
FSA40_RS09830	COG0632	four-way junction helicase activity
FSA40_RS09835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FSA40_RS09845	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FSA40_RS09855	COG1438	arginine binding
FSA40_RS09875	COG0018	arginyl-trna synthetase
FSA40_RS09880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FSA40_RS09885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FSA40_RS09890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSA40_RS09895	COG0124	histidyl-tRNA synthetase
FSA40_RS09900	COG0531	amino acid
FSA40_RS09905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FSA40_RS09910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FSA40_RS09930	COG0640	Transcriptional regulator
FSA40_RS09955	COG0789	Transcriptional regulator
FSA40_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
FSA40_RS09985	COG2094	Belongs to the DNA glycosylase MPG family
FSA40_RS10000	COG1733	regulation of RNA biosynthetic process
FSA40_RS10010	COG1012	belongs to the aldehyde dehydrogenase family
FSA40_RS10015	COG0129	dihydroxy-acid dehydratase activity
FSA40_RS10020	COG2151	metal-sulfur cluster biosynthetic enzyme
FSA40_RS10045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSA40_RS10060	COG0305	Participates in initiation and elongation during chromosome replication
FSA40_RS10065	COG0359	binds to the 23S rRNA
FSA40_RS10075	COG0445	tRNA wobble uridine modification
FSA40_RS10085	COG0482	sulfurtransferase activity
FSA40_RS10090	COG0741	lytic transglycosylase activity
FSA40_RS10100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FSA40_RS10105	COG1122	ATPase activity
FSA40_RS10110	COG1122	ATPase activity
FSA40_RS10115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSA40_RS10125	COG0612	Peptidase, M16
FSA40_RS10140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FSA40_RS10145	COG0517	IMP dehydrogenase activity
FSA40_RS10145	COG0516	GMP reductase activity
FSA40_RS10150	COG0180	Tryptophanyl-tRNA synthetase
FSA40_RS10155	COG0488	(ABC) transporter
FSA40_RS10185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FSA40_RS10190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain