locus-tag	class	description
HB751_RS00070	ENOG4105CFH	Aspartokinase
HB751_RS00075	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HB751_RS00080	ENOG4105CGU	Enoyl-CoA hydratase
HB751_RS00085	ENOG4105K56	Transcriptional regulator
HB751_RS00090	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HB751_RS00100	ENOG4105EA8	2-Nitropropane dioxygenase
HB751_RS00105	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HB751_RS00110	ENOG4105CHR	reductase
HB751_RS00115	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HB751_RS00125	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HB751_RS00130	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HB751_RS00155	ENOG4105DFU	Cell wall formation (By similarity)
HB751_RS00170	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HB751_RS00175	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
HB751_RS00185	ENOG4108RWN	rrna methyltransferase
HB751_RS00195	ENOG4105HFZ	Membrane
HB751_RS00200	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HB751_RS00205	ENOG4105VXM	UPF0154 protein
HB751_RS00210	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HB751_RS00215	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HB751_RS00230	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
HB751_RS00235	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HB751_RS00240	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HB751_RS00245	ENOG4105FE9	pseudouridine synthase
HB751_RS00250	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HB751_RS00255	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HB751_RS00260	ENOG4105C1A	potassium transporter peripheral membrane
HB751_RS00285	ENOG4108SAX	Membrane
HB751_RS00290	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HB751_RS00305	ENOG4105N5T	Radical SAM Protein
HB751_RS00315	ENOG4105DKW	ABC transporter
HB751_RS00320	ENOG4105C02	permease
HB751_RS00330	ENOG4105F1A	Pyruvate formate-lyase
HB751_RS00340	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
HB751_RS00345	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HB751_RS00350	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
HB751_RS00355	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
HB751_RS00360	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HB751_RS00370	ENOG4105D29	Helix-turn-helix type 11 domain protein
HB751_RS00375	ENOG4108V4B	ThiJ pfpI
HB751_RS00400	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HB751_RS00410	ENOG4105C28	cystathionine
HB751_RS00415	ENOG4105C87	Aminotransferase class I and II
HB751_RS00420	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HB751_RS00425	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HB751_RS00435	ENOG4105WUC	UPF0298 protein
HB751_RS00440	ENOG4105CP9	extracellular ligand-binding receptor
HB751_RS00445	ENOG4105C32	Amino acid ABC transporter (Permease)
HB751_RS00450	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HB751_RS00455	ENOG4105C0Z	ABC transporter
HB751_RS00460	ENOG4108IV0	ABC, transporter
HB751_RS00465	ENOG41080XP	Cbs domain
HB751_RS00470	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HB751_RS00475	ENOG4105FA2	dna polymerase iii
HB751_RS00480	ENOG4105MA4	psp1 domain protein
HB751_RS00485	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
HB751_RS00490	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HB751_RS00495	ENOG4105BZU	Histidine kinase
HB751_RS00500	ENOG4108YZA	Nitrogen regulatory protein pii
HB751_RS00505	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HB751_RS00515	ENOG4105M18	-acetyltransferase
HB751_RS00525	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HB751_RS00530	ENOG41080E8	Transcriptional regulator, Spx MgsR family
HB751_RS00535	ENOG4105CSM	endonuclease III
HB751_RS00540	ENOG4105CGK	Exodeoxyribonuclease III
HB751_RS00550	ENOG41082BM	Transcriptional regulator, arsr family
HB751_RS00585	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HB751_RS00615	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HB751_RS00635	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HB751_RS00640	ENOG4105CNU	cell division protein FtsK
HB751_RS00650	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HB751_RS00655	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HB751_RS00660	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HB751_RS00665	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HB751_RS00675	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HB751_RS00680	ENOG4106E6V	UPF0346 protein
HB751_RS00685	ENOG4105C9A	Phoh family
HB751_RS00690	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HB751_RS00695	ENOG4107YR5	Diacylglycerol kinase
HB751_RS00700	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HB751_RS00715	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HB751_RS00720	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HB751_RS00730	ENOG4105C6X	Major Facilitator
HB751_RS00745	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HB751_RS00750	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HB751_RS00760	ENOG4108RCM	Nitroreductase
HB751_RS00770	ENOG4105CS2	ec 3.2.1.21
HB751_RS00775	ENOG4105VZJ	PTS System
HB751_RS00780	ENOG4105EMD	TRANSCRIPTIONal
HB751_RS00785	ENOG4105VCP	PTS System
HB751_RS00795	ENOG4105CK1	PTS System
HB751_RS00815	ENOG4105ETE	Transcriptional regulator (LacI family
HB751_RS00825	ENOG4105W2C	Glycosyl transferase
HB751_RS00830	ENOG4105BZF	Glycosyl transferase (Group 1
HB751_RS00845	ENOG4105C22	threonyL-tRNA synthetase
HB751_RS00850	ENOG4108ZGC	gaf domain protein
HB751_RS00855	ENOG4105C6E	dna polymerase iii
HB751_RS00880	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HB751_RS00890	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HB751_RS00895	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HB751_RS00900	ENOG4108IJ9	(ABC) transporter
HB751_RS00905	ENOG4105EG2	ABC transporter, permease
HB751_RS00925	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
HB751_RS00930	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HB751_RS00940	ENOG4107VEG	TrkA-N domain protein
HB751_RS00990	ENOG4108M15	ABC transporter
HB751_RS01000	ENOG4105BZU	Histidine kinase
HB751_RS01005	ENOG4108S01	response regulator
HB751_RS01015	ENOG410807C	QueT transporter
HB751_RS01020	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HB751_RS01025	ENOG4105CBD	Diacylglycerol kinase
HB751_RS01030	ENOG4108IUM	Glycogen debranching enzyme
HB751_RS01035	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HB751_RS01040	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HB751_RS01045	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HB751_RS01050	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HB751_RS01060	ENOG4105ZA1	atp synthase
HB751_RS01065	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
HB751_RS01070	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HB751_RS01075	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HB751_RS01080	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HB751_RS01085	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HB751_RS01090	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HB751_RS01095	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HB751_RS01105	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HB751_RS01115	ENOG4105ZT7	DNA-entry nuclease
HB751_RS01120	ENOG4105DRP	amino acid AbC transporter
HB751_RS01125	ENOG4105EAD	ABC transporter
HB751_RS01130	ENOG4107RP9	extracellular solute-binding protein, family 3
HB751_RS01135	ENOG4105CDA	abc transporter atp-binding protein
HB751_RS01140	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HB751_RS01145	ENOG4105BZU	Histidine kinase
HB751_RS01150	ENOG4105Q2H	domain protein
HB751_RS01155	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HB751_RS01160	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HB751_RS01165	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HB751_RS01175	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HB751_RS01180	ENOG4105WT3	Transcriptional regulator
HB751_RS01185	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HB751_RS01215	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HB751_RS01220	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HB751_RS01225	ENOG4105E98	transcriptional regulator DeoR family
HB751_RS01230	ENOG4105RSI	Galactose-6-phosphate isomerase subunit LacA
HB751_RS01235	ENOG4108YZG	isomerase
HB751_RS01240	ENOG4106VEM	tagatose-6-phosphate kinase
HB751_RS01245	ENOG4105D2M	Aldolase
HB751_RS01250	ENOG4105VCP	PTS System
HB751_RS01255	ENOG4105CK1	PTS System
HB751_RS01260	ENOG4105CS2	ec 3.2.1.21
HB751_RS01290	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HB751_RS01320	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HB751_RS01325	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HB751_RS01335	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HB751_RS01340	ENOG4108IXY	short-chain dehydrogenase reductase
HB751_RS01345	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HB751_RS01350	ENOG4105D29	Helix-turn-helix type 11 domain protein
HB751_RS01370	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HB751_RS01375	ENOG4105CVG	Homoserine O-transsuccinylase
HB751_RS01395	ENOG4107VFR	oxidoreductase
HB751_RS01400	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HB751_RS01415	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HB751_RS01440	ENOG4107FQX	Alpha-acetolactate decarboxylase
HB751_RS01445	ENOG4105C85	amino acid
HB751_RS01465	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HB751_RS01480	ENOG4107UWA	esterase
HB751_RS01485	ENOG4106GP0	(LipO)protein
HB751_RS01495	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HB751_RS01510	ENOG4107R8N	Glycosyl transferase, family 2
HB751_RS01520	ENOG4105C5H	ABC transporter
HB751_RS01530	ENOG4105F1K	Glutamine amidotransferase
HB751_RS01535	ENOG4105DMS	mur ligase
HB751_RS01540	ENOG4105C8B	TIGR00159 family
HB751_RS01550	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HB751_RS01565	ENOG4107RUY	(E1 component), alpha subunit
HB751_RS01575	ENOG4107QKR	Dehydrogenase
HB751_RS01580	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
HB751_RS01590	ENOG4105CSA	Coproporphyrinogen iii oxidase
HB751_RS01605	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HB751_RS01615	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HB751_RS01640	ENOG4107SFZ	crispr-associated protein
HB751_RS01650	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
HB751_RS01670	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HB751_RS01690	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HB751_RS01725	ENOG4105D9R	oxidoreductase
HB751_RS01730	ENOG4105DBI	uridine monophosphokinase
HB751_RS01740	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HB751_RS01745	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HB751_RS01750	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HB751_RS01765	ENOG4105RHY	Pfam:UPF0157
HB751_RS01775	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HB751_RS01780	ENOG4107XNU	peptidase
HB751_RS01785	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HB751_RS01795	ENOG4105CAK	Cell division ATP-binding protein ftsE
HB751_RS01800	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HB751_RS01810	ENOG4105CHR	reductase
HB751_RS01815	ENOG4105CPF	Cell wall formation (By similarity)
HB751_RS01840	ENOG4108JJB	ABC transporter
HB751_RS01855	ENOG4105CHM	Aminotransferase
HB751_RS01860	ENOG4105C5S	asparaginyl-tRNA synthetase
HB751_RS01870	ENOG4105KME	endoribonuclease L-psp
HB751_RS01880	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HB751_RS01890	ENOG4105CIE	May be required for sporulation (By similarity)
HB751_RS01905	ENOG4105DVA	methyltransferase
HB751_RS01920	ENOG41082DI	50s ribosomal protein l31
HB751_RS01925	ENOG4105SFS	phosphoesterase RecJ domain protein
HB751_RS01935	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HB751_RS01940	ENOG4105NQC	Flavodoxin
HB751_RS01955	ENOG4105CQC	Prephenate dehydratase
HB751_RS01960	ENOG4107R4J	Chloride channel
HB751_RS01965	ENOG4107R4J	Chloride channel
HB751_RS01970	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HB751_RS02020	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
HB751_RS02030	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HB751_RS02035	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HB751_RS02040	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HB751_RS02045	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HB751_RS02050	ENOG4105EAC	phosphoserine phosphatase
HB751_RS02055	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HB751_RS02065	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HB751_RS02070	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HB751_RS02075	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HB751_RS02080	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HB751_RS02160	ENOG4107XGZ	Hydrolase
HB751_RS02170	ENOG4105BZW	Glycerate kinase
HB751_RS02190	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HB751_RS02210	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HB751_RS02220	ENOG4107QSE	Dipeptidase
HB751_RS02225	ENOG4108RG0	uracil-dna glycosylase
HB751_RS02245	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HB751_RS02250	ENOG4105E66	phosphoriboisomerase A
HB751_RS02255	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HB751_RS02280	ENOG41089BK	Glutamine amido-transferase
HB751_RS02285	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HB751_RS02300	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
HB751_RS02305	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HB751_RS02310	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HB751_RS02315	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HB751_RS02320	ENOG4105KIS	phospholipid-binding protein
HB751_RS02325	ENOG4105UNS	Pfam:DUF419
HB751_RS02335	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
HB751_RS02340	ENOG4105E5Q	amino acid AbC transporter
HB751_RS02345	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HB751_RS02355	ENOG4105CGH	5'-nucleotidase
HB751_RS02360	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HB751_RS02365	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HB751_RS02380	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HB751_RS02400	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HB751_RS02430	ENOG4105CZV	ABC transporter
HB751_RS02435	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
HB751_RS02445	ENOG4105CTQ	phosphohexokinase
HB751_RS02450	ENOG4105CA9	Pyruvate kinase
HB751_RS02455	ENOG4107BMA	Transglycosylase associated protein
HB751_RS02465	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HB751_RS02470	ENOG4105CTS	PTS system mannitol-specific
HB751_RS02475	ENOG4105EMD	TRANSCRIPTIONal
HB751_RS02480	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HB751_RS02485	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
HB751_RS02490	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HB751_RS02495	ENOG4105E5Q	amino acid AbC transporter
HB751_RS02500	ENOG4105CDA	abc transporter atp-binding protein
HB751_RS02505	ENOG4106TNF	Periplasmic binding protein
HB751_RS02515	ENOG4105BZG	amino acid carrier protein
HB751_RS02520	ENOG4105C4R	Atp-dependent dna helicase
HB751_RS02540	ENOG4107QIV	Cytochrome c biogenesis protein
HB751_RS02545	ENOG4107USA	Thioredoxin
HB751_RS02580	ENOG4105BZ1	(ABC) transporter
HB751_RS02645	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HB751_RS02655	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HB751_RS02660	ENOG4105DTN	riboflavin biosynthesis protein ribF
HB751_RS02665	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HB751_RS02670	ENOG4105WBI	UPF0223 protein
HB751_RS02675	ENOG4105ECY	inositol monophosphatase
HB751_RS02680	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HB751_RS02690	ENOG4105C8U	phosphate abc transporter
HB751_RS02695	ENOG4105E2Z	phosphate ABC transporter (Permease
HB751_RS02700	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HB751_RS02705	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HB751_RS02710	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HB751_RS02725	ENOG4108STX	response regulator
HB751_RS02730	ENOG4105US7	Histidine kinase
HB751_RS02735	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HB751_RS02740	ENOG4105CS9	pantothenic acid kinase
HB751_RS02745	ENOG4107Y49	methyltransferase
HB751_RS02750	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HB751_RS02760	ENOG4105KG3	cytidine deaminase
HB751_RS02765	ENOG4105DIH	basic membrane
HB751_RS02770	ENOG4108JQ9	ABC transporter
HB751_RS02775	ENOG4105UIB	(ABC) transporter
HB751_RS02795	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HB751_RS02805	ENOG4108Z6X	(sortase) family
HB751_RS02810	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HB751_RS02820	ENOG4105K3M	)-transporter
HB751_RS02825	ENOG4108HCJ	Hydrolase
HB751_RS02855	ENOG4105CS2	ec 3.2.1.21
HB751_RS02860	ENOG4105C02	permease
HB751_RS02880	ENOG4105E90	ABC transporter
HB751_RS02890	ENOG4107WD8	ABC transporter, permease
HB751_RS02900	ENOG4107EFR	Flavocytochrome c
HB751_RS02915	ENOG41069HH	4-oxalocrotonate tautomerase
HB751_RS02920	ENOG4107104	thymidine kinase
HB751_RS02925	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HB751_RS02930	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HB751_RS02935	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HB751_RS02940	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HB751_RS02955	ENOG4105BZ1	(ABC) transporter
HB751_RS02960	ENOG4105BZ1	(ABC) transporter
HB751_RS02970	ENOG4105FH5	Membrane
HB751_RS02975	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HB751_RS02985	ENOG4105CKU	formyltetrahydrofolate synthetase
HB751_RS02990	ENOG4107Y3V	-acetyltransferase
HB751_RS03010	ENOG4105CIG	ABC transporter
HB751_RS03020	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HB751_RS03085	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HB751_RS03100	ENOG4108IJ7	Glycine betaine
HB751_RS03110	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
HB751_RS03115	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HB751_RS03145	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HB751_RS03155	ENOG4105C3J	Cysteine desulfurase
HB751_RS03160	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HB751_RS03165	ENOG4105MIX	Adenylate cyclase
HB751_RS03180	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HB751_RS03185	ENOG4105EMS	pseudouridine synthase
HB751_RS03190	ENOG4108IJ2	phosphate acetyltransferase
HB751_RS03200	ENOG4105CJ1	ABC, transporter
HB751_RS03205	ENOG4105EMU	Dehydrogenase
HB751_RS03210	ENOG4105X1N	Glycosyl transferase family 8
HB751_RS03215	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HB751_RS03220	ENOG4105BZU	Histidine kinase
HB751_RS03235	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
HB751_RS03250	ENOG4107QSA	Oxaloacetate decarboxylase
HB751_RS03270	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
HB751_RS03275	ENOG4105D9Q	decarboxylase (Beta subunit)
HB751_RS03280	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
HB751_RS03290	ENOG4105D4T	Citrate transporter
HB751_RS03300	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HB751_RS03305	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
HB751_RS03310	ENOG4105EWM	Histidine kinase
HB751_RS03315	ENOG4105CJZ	response regulator
HB751_RS03330	ENOG4106ISY	Putative cell wall binding repeat
HB751_RS03335	ENOG4108N67	choline binding protein
HB751_RS03340	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
HB751_RS03345	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HB751_RS03350	ENOG4105C79	DNA protecting protein DprA
HB751_RS03365	ENOG4108IPW	abc transporter atp-binding protein
HB751_RS03370	ENOG4105CM4	permease protein
HB751_RS03375	ENOG4105DHS	permease protein
HB751_RS03380	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HB751_RS03385	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HB751_RS03400	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HB751_RS03405	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HB751_RS03415	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HB751_RS03420	ENOG4108M1Z	surface protein
HB751_RS03450	ENOG4105C5Y	PTS System
HB751_RS03455	ENOG4105CID	antiterminator
HB751_RS03460	ENOG4108HM4	ABC transporter
HB751_RS03465	ENOG4105D38	putrescine abc transporter
HB751_RS03470	ENOG4105F38	ABC transporter, permease
HB751_RS03475	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HB751_RS03480	ENOG4105D4A	Cell wall formation (By similarity)
HB751_RS03500	ENOG4105EUJ	GTP cyclohydrolase i
HB751_RS03505	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HB751_RS03510	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HB751_RS03515	ENOG4105D6E	homoserine dehydrogenase
HB751_RS03520	ENOG4107BJW	polysaccharide deacetylase
HB751_RS03525	ENOG4105C1G	acyl-Coa dehydrogenase
HB751_RS03535	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HB751_RS03540	ENOG4108VZM	50s ribosomal protein L10
HB751_RS03565	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HB751_RS03570	ENOG4108J5H	Homocysteine s-methyltransferase
HB751_RS03575	ENOG4108IQI	permease
HB751_RS03580	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HB751_RS03585	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HB751_RS03595	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HB751_RS03605	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HB751_RS03610	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
HB751_RS03625	ENOG4108UT2	hemolysin iii
HB751_RS03630	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HB751_RS03645	ENOG4105CDA	abc transporter atp-binding protein
HB751_RS03670	ENOG4107R11	Transcriptional regulator
HB751_RS03675	ENOG4105KA3	membrAne
HB751_RS03685	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HB751_RS03700	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HB751_RS03705	ENOG4105BZ1	(ABC) transporter
HB751_RS03720	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HB751_RS03730	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HB751_RS03735	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HB751_RS03745	ENOG4105D82	Glutamate dehydrogenase
HB751_RS03775	ENOG4105C5H	ABC transporter
HB751_RS03780	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HB751_RS03785	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HB751_RS03790	ENOG4105EPR	degv family
HB751_RS03810	ENOG4108IG5	Transcriptional regulator
HB751_RS03825	ENOG4105CMR	udp-glucose 4-epimerase
HB751_RS03835	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HB751_RS03840	ENOG4105CQ4	Transcriptional regulator
HB751_RS03845	ENOG4105CG3	alpha amylase, catalytic region
HB751_RS03850	ENOG4108IJ9	(ABC) transporter
HB751_RS03855	ENOG4107RK0	Sucrose phosphorylase
HB751_RS03870	ENOG4107YY3	extracellular solute-binding protein family 1
HB751_RS03875	ENOG4105DME	alpha-galactosidase
HB751_RS03880	ENOG4108R6W	Transcriptional regulator, ARAC family
HB751_RS03890	ENOG4105DQ6	Transposase
HB751_RS03900	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HB751_RS03905	ENOG4105DM4	PTS System
HB751_RS03910	ENOG4105DE4	1-phosphofructokinase
HB751_RS03915	ENOG4105E98	transcriptional regulator DeoR family
HB751_RS03920	ENOG4105CAY	ferredoxin--nadp reductase
HB751_RS03925	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HB751_RS03930	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HB751_RS03935	ENOG4105VB6	UPF0109 protein
HB751_RS03940	ENOG4105K5M	30s ribosomal protein S16
HB751_RS03945	ENOG4107RBB	ABC transporter, permease
HB751_RS03950	ENOG4105C19	ABC transporter
HB751_RS03960	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HB751_RS03965	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HB751_RS03970	ENOG4105CXT	aspartate transcarbamylase
HB751_RS03980	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HB751_RS03990	ENOG4105C34	Pseudouridine synthase
HB751_RS03995	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HB751_RS04000	ENOG4107R11	Transcriptional regulator
HB751_RS04005	ENOG4105E09	nadh pyrophosphatase
HB751_RS04015	ENOG4105K46	50S ribosomal protein l27
HB751_RS04025	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HB751_RS04045	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HB751_RS04050	ENOG4105C3J	Cysteine desulfurase
HB751_RS04060	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HB751_RS04065	ENOG4105DC8	reductase
HB751_RS04075	ENOG41068JE	domain protein
HB751_RS04085	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
HB751_RS04090	ENOG4105CKK	Glycosyl transferase, family 2
HB751_RS04100	ENOG4107T7U	Sulfatase
HB751_RS04115	ENOG4105EY8	ABC transporter
HB751_RS04125	ENOG4105K64	Glycosyl transferase, family 2
HB751_RS04135	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HB751_RS04140	ENOG4105VG1	fes assembly suf system protein
HB751_RS04145	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HB751_RS04150	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HB751_RS04160	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HB751_RS04170	ENOG4106TNF	Periplasmic binding protein
HB751_RS04180	ENOG4107R0W	ABC transporter
HB751_RS04185	ENOG4108Z4K	mutator MutT protein
HB751_RS04205	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HB751_RS04215	ENOG4106PMH	Extracellular solute-binding protein family 3
HB751_RS04220	ENOG4105CDA	abc transporter atp-binding protein
HB751_RS04225	ENOG4105C5H	ABC transporter
HB751_RS04235	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HB751_RS04290	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HB751_RS04295	ENOG4108RCF	TRANSCRIPTIONal
HB751_RS04300	ENOG4105CQC	Prephenate dehydratase
HB751_RS04305	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HB751_RS04310	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HB751_RS04315	ENOG4105WZB	UPF0342 protein
HB751_RS04320	ENOG4105EVN	Prephenate dehydrogenase
HB751_RS04325	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HB751_RS04330	ENOG4105D49	3-dehydroquinate synthase
HB751_RS04335	ENOG4105E2X	shikimate dehydrogenase
HB751_RS04340	ENOG4105FF2	Type I DHQase
HB751_RS04345	ENOG4105DR4	Methyltransferase
HB751_RS04370	ENOG4105CRK	lysyL-tRNA synthetase
HB751_RS04380	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HB751_RS04385	ENOG4105VEM	Conserved domain protein
HB751_RS04405	ENOG4105D3R	alkyl hydroperoxide reductase
HB751_RS04410	ENOG4105CFP	Peptidase U32
HB751_RS04435	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HB751_RS04440	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HB751_RS04450	ENOG410906U	SprT-like
HB751_RS04460	ENOG4108PJD	permease
HB751_RS04465	ENOG4108NNR	transporter substrate-binding protein
HB751_RS04470	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HB751_RS04475	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HB751_RS04480	ENOG410667J	hydrolase
HB751_RS04485	ENOG4108HCJ	Hydrolase
HB751_RS04525	ENOG4105CIG	ABC transporter
HB751_RS04550	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HB751_RS04570	ENOG4105DCI	Phosphohydrolase
HB751_RS04590	ENOG4105CP7	Triose-phosphate isomerase
HB751_RS04595	ENOG4108JJA	ABC, transporter
HB751_RS04630	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HB751_RS04635	ENOG4105CNI	cell division protein FtsW
HB751_RS04640	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HB751_RS04660	ENOG41084PM	thiamine transporter
HB751_RS04665	ENOG410907Z	n-acetylmuramoyl-l-alanine amidase
HB751_RS04675	ENOG4108Z66	YbaK ebsC protein
HB751_RS04685	ENOG4108TGR	phosphatase
HB751_RS04690	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HB751_RS04695	ENOG4105VJV	50s ribosomal protein L35
HB751_RS04700	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HB751_RS04705	ENOG4105CAT	Cytidine monophosphate kinase
HB751_RS04725	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HB751_RS04760	ENOG4108F5E	vimentin
HB751_RS04785	ENOG4105VUF	Transcriptional regulator
HB751_RS04790	ENOG4105C26	Dehydrogenase
HB751_RS04795	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HB751_RS04800	ENOG4105KRI	phosphocarrier protein (HPr
HB751_RS04810	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HB751_RS04815	ENOG4105BZN	citrate synthase
HB751_RS04820	ENOG4108I0Z	Aconitate hydratase
HB751_RS04825	ENOG41067VN	Glutaredoxin
HB751_RS04830	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HB751_RS04840	ENOG4105C8Y	Acetylornithine aminotransferase
HB751_RS04850	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HB751_RS04855	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HB751_RS04895	ENOG4105DA5	(ABC) transporter
HB751_RS04915	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HB751_RS04925	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HB751_RS04935	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HB751_RS04970	ENOG4107U9B	transcriptional regulator
HB751_RS04990	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HB751_RS05000	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HB751_RS05025	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HB751_RS05045	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HB751_RS05050	ENOG4105KQC	Competence protein
HB751_RS05055	ENOG4105F6E	Acyl-transferase
HB751_RS05060	ENOG4108ZJ4	polysaccharide deacetylase
HB751_RS05070	ENOG41060K3	Methyltransferase
HB751_RS05095	ENOG4105C1J	atp-dependent rna helicase
HB751_RS05110	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HB751_RS05120	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HB751_RS05125	ENOG4105C09	Bile acid
HB751_RS05135	ENOG4105CPF	Cell wall formation (By similarity)
HB751_RS05140	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HB751_RS05145	ENOG4107RF6	penicillin-binding protein
HB751_RS05150	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HB751_RS05165	ENOG4105G5W	regulator Fur family
HB751_RS05180	ENOG4105DQ6	Transposase
HB751_RS05185	ENOG4105K70	DNA-binding protein
HB751_RS05195	ENOG41090WU	lipolytic protein G-D-S-L family
HB751_RS05200	ENOG4108RCR	degv family
HB751_RS05205	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HB751_RS05210	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HB751_RS05215	ENOG4105DX0	Hemolysin A
HB751_RS05225	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HB751_RS05230	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HB751_RS05235	ENOG4108KHS	signal transduction Histidine kinase
HB751_RS05250	ENOG41067MG	lrgb family
HB751_RS05255	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HB751_RS05270	ENOG4105CE1	Ferrous iron transport protein b
HB751_RS05280	ENOG4105CDA	abc transporter atp-binding protein
HB751_RS05285	ENOG4105E5Q	amino acid AbC transporter
HB751_RS05290	ENOG4107IN1	Protein of unknown function (DUF1797)
HB751_RS05300	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HB751_RS05315	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HB751_RS05320	ENOG4105MMF	Cell division protein DIVIVA
HB751_RS05325	ENOG4105DBK	s4 domain protein
HB751_RS05335	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HB751_RS05340	ENOG4105DFA	alanine racemase domain protein
HB751_RS05350	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HB751_RS05360	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HB751_RS05365	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HB751_RS05375	ENOG4105CI3	gtp-binding protein typa
HB751_RS05380	ENOG4107YZP	Rhodanese domain protein
HB751_RS05385	ENOG4105DKQ	ROK family
HB751_RS05395	ENOG4105HUF	DNA protection during starvation protein
HB751_RS05405	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HB751_RS05410	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HB751_RS05415	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HB751_RS05420	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HB751_RS05425	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HB751_RS05430	ENOG4105DDQ	anthranilate synthase
HB751_RS05435	ENOG4105CRQ	synthase (Component I)
HB751_RS05455	ENOG4108KR4	dihydrodipicolinate reductase
HB751_RS05465	ENOG4105BZ1	(ABC) transporter
HB751_RS05470	ENOG4105BZ1	(ABC) transporter
HB751_RS05480	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HB751_RS05485	ENOG4105MMD	transcriptional regulator
HB751_RS05490	ENOG4107R8B	5'-nucleotidase
HB751_RS05495	ENOG41063PX	domain protein
HB751_RS05500	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HB751_RS05505	ENOG4106H78	methyltransferase
HB751_RS05510	ENOG4105CCI	Myosin-Cross-Reactive Antigen
HB751_RS05550	ENOG410667J	hydrolase
HB751_RS05555	ENOG4105E98	transcriptional regulator DeoR family
HB751_RS05600	ENOG4105MJ2	Competence protein
HB751_RS05610	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HB751_RS05635	ENOG4107EDW	L-fucose operon activator
HB751_RS05640	ENOG4105F1A	Pyruvate formate-lyase
HB751_RS05655	ENOG4105WH1	Two component transcriptional regulator luxr family
HB751_RS05660	ENOG4105ENE	Histidine kinase
HB751_RS05670	ENOG4105D9P	serine threonine protein kinase
HB751_RS05680	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HB751_RS05685	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HB751_RS05690	ENOG4105C25	Primosomal protein n'
HB751_RS05695	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HB751_RS05700	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HB751_RS05705	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HB751_RS05710	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HB751_RS05715	ENOG41070VT	
HB751_RS05720	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HB751_RS05730	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
HB751_RS05735	ENOG4108UKS	UPF0398 protein
HB751_RS05740	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
HB751_RS05745	ENOG4105BZ4	penicillin-binding protein
HB751_RS05750	ENOG4105CTZ	aminopeptidase c
HB751_RS05755	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HB751_RS05760	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HB751_RS05765	ENOG4105C3M	thioredoxin reductase
HB751_RS05775	ENOG4105CDA	abc transporter atp-binding protein
HB751_RS05780	ENOG4105E5Q	amino acid AbC transporter
HB751_RS05790	ENOG4105C1J	atp-dependent rna helicase
HB751_RS05800	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HB751_RS05805	ENOG4105CJN	penicillin-binding protein
HB751_RS05810	ENOG41068DC	Essential cell division protein (By similarity)
HB751_RS05815	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HB751_RS05820	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HB751_RS05825	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HB751_RS05835	ENOG4105VPS	UPF0291 protein
HB751_RS05840	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HB751_RS05845	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HB751_RS05850	ENOG4105M5P	UPF0310 protein
HB751_RS05870	ENOG4105CIZ	coA-substrate-specific enzyme activase
HB751_RS05875	ENOG4105CE4	GlcNAc 6-P deacetylase
HB751_RS05905	ENOG410667J	hydrolase
HB751_RS05915	ENOG4105C59	p-type ATPase
HB751_RS05920	ENOG4105NA0	Transcriptional regulator
HB751_RS05935	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HB751_RS05940	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HB751_RS05950	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
HB751_RS05955	ENOG4105CHV	Transcription elongation factor NusA
HB751_RS05960	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HB751_RS05970	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HB751_RS05990	ENOG4105K59	histidine triad (HIT) protein
HB751_RS06000	ENOG4108KGH	TRANSCRIPTIONal
HB751_RS06005	ENOG4108097	ATP-binding protein
HB751_RS06010	ENOG4105C7N	Xanthine uracil vitamin C permease
HB751_RS06020	ENOG4108KP7	hydrolase
HB751_RS06035	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HB751_RS06040	ENOG4105C6N	Formate acetyltransferase
HB751_RS06050	ENOG4107S1E	Beta-lactamase
HB751_RS06060	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HB751_RS06065	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
HB751_RS06080	ENOG4107QMH	DNA methylase
HB751_RS06115	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
HB751_RS06120	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HB751_RS06130	ENOG4105CBX	hi0933 family
HB751_RS06135	ENOG4105G7B	Protein of unknown function (DUF2992)
HB751_RS06150	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HB751_RS06155	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HB751_RS06160	ENOG41072GX	Peptidase M22 Glycoprotease
HB751_RS06175	ENOG4107S5I	aldo keto reductase
HB751_RS06195	ENOG4106EHS	UPF0356 protein
HB751_RS06205	ENOG41068JE	domain protein
HB751_RS06210	ENOG4105BZ8	glutamate synthase
HB751_RS06215	ENOG4105CBC	glutamate synthase
HB751_RS06220	ENOG4105C5F	glutamine synthetase
HB751_RS06225	ENOG4105KV4	Transcriptional regulator
HB751_RS06235	ENOG4105BZA	Phosphoglycerate kinase
HB751_RS06240	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HB751_RS06245	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HB751_RS06250	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HB751_RS06255	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HB751_RS06260	ENOG4105DFT	pur operon repressor
HB751_RS06265	ENOG4105EQI	Metal Dependent Phosphohydrolase
HB751_RS06280	ENOG4105DJV	ribulose-phosphate 3-epimerase
HB751_RS06285	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HB751_RS06305	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HB751_RS06320	ENOG4105KVH	Transcriptional regulator
HB751_RS06340	ENOG4105F8V	Hydrolase, tatD family
HB751_RS06345	ENOG4105VG0	50S ribosomal protein l34
HB751_RS06365	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HB751_RS06370	ENOG4105CH7	arginosuccinase
HB751_RS06375	ENOG4105CDH	Citrulline--aspartate ligase
HB751_RS06385	ENOG4105RNB	
HB751_RS06390	ENOG4108Z3G	3H domain protein
HB751_RS06395	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HB751_RS06420	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HB751_RS06425	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HB751_RS06430	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HB751_RS06435	ENOG4107ZXI	Rhomboid family
HB751_RS06440	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HB751_RS06445	ENOG4105CH2	amidohydrolase
HB751_RS06450	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HB751_RS06465	ENOG4105DZY	Pts system, glucitol sorbitol-specific
HB751_RS06470	ENOG410787A	Pts system, glucitol sorbitol-specific
HB751_RS06480	ENOG4105EMD	TRANSCRIPTIONal
HB751_RS06485	ENOG4105CHR	reductase
HB751_RS06490	ENOG4107QYV	phosphohexose isomerase
HB751_RS06510	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HB751_RS06520	ENOG4105W8Z	4'-phosphopantetheinyl transferase
HB751_RS06530	ENOG4105C19	ABC transporter
HB751_RS06550	ENOG4105CJ1	ABC, transporter
HB751_RS06560	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HB751_RS06600	ENOG4108RQ5	Beta-lactamase domain-containing protein
HB751_RS06615	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HB751_RS06625	ENOG4105K4P	CoA-binding domain protein
HB751_RS06630	ENOG4105C2M	dna polymerase I
HB751_RS06645	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
HB751_RS06675	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HB751_RS06690	ENOG4107VK6	Transport protein ComB
HB751_RS06695	ENOG4108JJA	ABC, transporter
HB751_RS06745	ENOG4106ETB	IIa component
HB751_RS06760	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HB751_RS06765	ENOG4105D9M	gamma-glutamylcysteine synthetase
HB751_RS06775	ENOG4108JQ7	(ABC) transporter
HB751_RS06785	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HB751_RS06790	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HB751_RS06795	ENOG4108J59	Extracellular solute-binding protein, family 5
HB751_RS06810	ENOG4105DIW	FeS assembly protein SUFB
HB751_RS06815	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HB751_RS06825	ENOG4105JRK	feS assembly protein SufD
HB751_RS06835	ENOG4105ESV	Glycosyl transferase, family 4
HB751_RS06840	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HB751_RS06845	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HB751_RS06855	ENOG4105E5Q	amino acid AbC transporter
HB751_RS06860	ENOG4105CDA	abc transporter atp-binding protein
HB751_RS06870	ENOG4105CJ1	ABC, transporter
HB751_RS06880	ENOG4105MKU	Transcriptional regulator
HB751_RS06890	ENOG4105C7B	Threonine dehydratase
HB751_RS06895	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HB751_RS06900	ENOG4108ZP8	Acetolactate synthase small subunit
HB751_RS07025	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HB751_RS07030	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HB751_RS07040	ENOG4105DSE	periplasmic solute binding protein
HB751_RS07045	ENOG4105CC5	ABC transporter
HB751_RS07050	ENOG4105DIK	(ABC) transporter
HB751_RS07055	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HB751_RS07060	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HB751_RS07065	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HB751_RS07075	ENOG4105CK1	PTS System
HB751_RS07115	ENOG4105KTU	Transcriptional regulator, arsr family
HB751_RS07135	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HB751_RS07140	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HB751_RS07160	ENOG4108A65	Transcriptional regulator
HB751_RS07205	ENOG4108UJD	30S ribosomal protein S9
HB751_RS07210	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HB751_RS07215	ENOG4105VZ8	Transcriptional regulator
HB751_RS07230	ENOG4105EPR	degv family
HB751_RS07235	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HB751_RS07260	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HB751_RS07265	ENOG4105C8N	cysteinyl-tRNA synthetase
HB751_RS07270	ENOG4105D7W	serine acetyltransferase
HB751_RS07280	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HB751_RS07285	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HB751_RS07290	ENOG4105C0A	alcohol dehydrogenase
HB751_RS07300	ENOG4108Y4K	DNA-binding transcriptional activator
HB751_RS07305	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HB751_RS07320	ENOG4105F0F	Oxalate decarboxylase
HB751_RS07325	ENOG4108N2Y	auxin Efflux
HB751_RS07330	ENOG4105C6K	Malic enzyme
HB751_RS07340	ENOG4107ZGM	malolactic fermentation system
HB751_RS07345	ENOG4105XEA	Tetr family transcriptional regulator
HB751_RS07350	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HB751_RS07360	ENOG4105DF9	Lipoate-protein, ligase
HB751_RS07365	ENOG4107QN2	dihydrolipoyl dehydrogenase
HB751_RS07375	ENOG4105CPP	Dehydrogenase, E1 component
HB751_RS07380	ENOG4107RUY	(E1 component), alpha subunit
HB751_RS07385	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HB751_RS07390	ENOG41090MY	MarR family Transcriptional regulator
HB751_RS07395	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HB751_RS07400	ENOG4107QJQ	Mate efflux family protein
HB751_RS07405	ENOG4105VB9	50S ribosomal protein l28
HB751_RS07410	ENOG4108I9Z	alcohol dehydrogenase
HB751_RS07415	ENOG4105C4W	S-formylglutathione hydrolase
HB751_RS07425	ENOG4105D2M	Aldolase
HB751_RS07430	ENOG4105DM4	PTS System
HB751_RS07435	ENOG4105DM4	PTS System
HB751_RS07440	ENOG4105DE4	1-phosphofructokinase
HB751_RS07450	ENOG4105WT3	Transcriptional regulator
HB751_RS07500	ENOG4105ETZ	PTS System
HB751_RS07510	ENOG4105D2N	Aldolase
HB751_RS07530	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HB751_RS07545	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HB751_RS07555	ENOG4105D8X	mechanosensitive ion channel
HB751_RS07560	ENOG4108UIC	UPF0340 protein
HB751_RS07565	ENOG4105PUK	Membrane
HB751_RS07575	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HB751_RS07580	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HB751_RS07585	ENOG4105CFG	Acts as a chaperone (By similarity)
HB751_RS07590	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HB751_RS07595	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HB751_RS07605	ENOG4105D7K	pfkb domain protein
HB751_RS07610	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HB751_RS07625	ENOG4105CAG	UPF0210 protein
HB751_RS07630	ENOG4105VUC	UPF0237 protein
HB751_RS07635	ENOG4105UQX	Mate efflux family protein
HB751_RS07640	ENOG4105D98	threonine synthase
HB751_RS07655	ENOG4105KJF	protein tyrosine phosphatase
HB751_RS07660	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HB751_RS07680	ENOG4105C83	adenylosuccinate lyase
HB751_RS07705	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HB751_RS07710	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HB751_RS07720	ENOG4105C12	Phosphoribosylglycinamide synthetase
HB751_RS07740	ENOG4107U4J	modification
HB751_RS07760	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HB751_RS07765	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HB751_RS07770	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HB751_RS07775	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HB751_RS07795	ENOG4105C8V	SAICAR synthetase
HB751_RS07800	ENOG4108JJA	ABC, transporter
HB751_RS07805	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HB751_RS07810	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HB751_RS07815	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
HB751_RS07820	ENOG4105CHM	Aminotransferase
HB751_RS07825	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HB751_RS07830	ENOG41068JE	domain protein
HB751_RS07840	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HB751_RS07950	ENOG4105CUB	amino acid
HB751_RS07955	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HB751_RS07960	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HB751_RS07965	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HB751_RS07985	ENOG41082I2	s4 domain protein
HB751_RS07990	ENOG4108JA2	transcriptioN-repair coupling factor
HB751_RS07995	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HB751_RS08000	ENOG4105C3G	gtp-binding protein
HB751_RS08010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HB751_RS08015	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HB751_RS08020	ENOG4105FA0	parb-like partition protein
HB751_RS08025	ENOG4105C0H	protease
HB751_RS08030	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HB751_RS08060	ENOG4105C5H	ABC transporter
HB751_RS08065	ENOG4105C31	Tryptophanyl-tRNA synthetase
HB751_RS08070	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HB751_RS08075	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HB751_RS08100	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HB751_RS08105	ENOG4108JJB	ABC transporter
HB751_RS08110	ENOG4108JJB	ABC transporter
HB751_RS08115	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HB751_RS08120	ENOG41068JE	domain protein
HB751_RS08125	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
HB751_RS08130	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HB751_RS08150	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HB751_RS08155	ENOG4105CDU	Replicative dna helicase
HB751_RS08165	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HB751_RS08185	ENOG4105VG1	fes assembly suf system protein
HB751_RS08190	ENOG4105C01	Dihydroxy-acid dehydratase
HB751_RS08220	ENOG4108VX5	3-methyladenine DNA glycosylase
HB751_RS08245	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
HB751_RS08275	ENOG41082BM	Transcriptional regulator, arsr family
HB751_RS08295	ENOG41086FC	50S ribosomal protein l32
HB751_RS08300	ENOG4105C0X	amino acid
HB751_RS08305	ENOG4105CUT	histidyl-tRNA synthetase
HB751_RS08310	ENOG4105C9M	aspartyl-trna synthetase
HB751_RS08315	ENOG4107AYK	membrAne
HB751_RS08320	ENOG4108JYZ	YitT family
HB751_RS08325	ENOG4105C75	arginyL-tRNA synthetase
HB751_RS08345	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HB751_RS08355	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HB751_RS08365	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HB751_RS08370	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HB751_RS08375	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HB751_RS08380	ENOG4105CEV	competence damage-inducible protein
HB751_RS08385	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HB751_RS08390	ENOG410888K	transcriptional regulator, Spx
HB751_RS08415	ENOG4105VBH	UPF0297 protein
HB751_RS08420	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HB751_RS08425	ENOG4105VPH	UPF0473 protein
HB751_RS08435	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HB751_RS08445	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HB751_RS08475	ENOG4105CKK	Glycosyl transferase, family 2
HB751_RS08485	ENOG4105CMR	udp-glucose 4-epimerase
HB751_RS08495	ENOG4107QT5	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HB751_RS08505	ENOG4105DUM	transcriptional regulator, lysR family
HB751_RS08510	ENOG4105HMI	Membrane
HB751_RS08520	ENOG4105C59	p-type ATPase
HB751_RS08535	ENOG4105D1H	recombination factor protein RarA
HB751_RS08555	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HB751_RS08560	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HB751_RS08575	ENOG4105CI1	PTS System
HB751_RS08590	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HB751_RS08595	ENOG4107PMM	dextranase
HB751_RS08605	ENOG4107414	GntR family transcriptional regulator
HB751_RS08610	ENOG4105C5Y	PTS System
HB751_RS08615	ENOG4105CG3	alpha amylase, catalytic region
HB751_RS08625	ENOG4105C9K	Endothelin-converting enzyme 1
HB751_RS08645	ENOG4105CE9	30S ribosomal protein S2
HB751_RS08650	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HB751_RS08695	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HB751_RS08710	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HB751_RS08715	ENOG4105EDQ	levansucrase EC 2.4.1.10
HB751_RS08730	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HB751_RS08745	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HB751_RS08755	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HB751_RS08760	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HB751_RS08765	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HB751_RS08770	ENOG41082SA	50s ribosomal protein l29
HB751_RS08775	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HB751_RS08780	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HB751_RS08785	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HB751_RS08790	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HB751_RS08795	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HB751_RS08800	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HB751_RS08805	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HB751_RS08815	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HB751_RS08820	ENOG4105VPB	50S ribosomal protein L30
HB751_RS08825	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HB751_RS08830	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HB751_RS08835	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HB751_RS08840	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HB751_RS08850	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HB751_RS08855	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HB751_RS08860	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HB751_RS08865	ENOG4108ZT0	50S ribosomal protein l17
HB751_RS08905	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HB751_RS08915	ENOG4105FDK	ABC transporter
HB751_RS08925	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HB751_RS08930	ENOG4105BZ4	penicillin-binding protein
HB751_RS08935	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HB751_RS08940	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HB751_RS08990	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HB751_RS09015	ENOG4105II7	pyrroline-5-carboxylate reductase
HB751_RS09035	ENOG4108VDD	TRNA binding domain protein
HB751_RS09060	ENOG4105BZU	Histidine kinase
HB751_RS09065	ENOG4105WH1	Two component transcriptional regulator luxr family
HB751_RS09090	ENOG4105ETZ	PTS System
HB751_RS09095	ENOG4105F3R	pts system mannose fructose sorbose family iid
HB751_RS09105	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HB751_RS09110	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HB751_RS09120	ENOG4108YBP	pseudouridine synthase
HB751_RS09125	ENOG4105BZ4	penicillin-binding protein
HB751_RS09155	ENOG4105C8T	Leucyl-tRNA synthetase
HB751_RS09165	ENOG4105DA5	(ABC) transporter
HB751_RS09205	ENOG4105D01	(LipO)protein
HB751_RS09210	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HB751_RS09215	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HB751_RS09225	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HB751_RS09235	ENOG4108V7D	UPF0397 protein
HB751_RS09240	ENOG4108JJB	ABC transporter
HB751_RS09250	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HB751_RS09255	ENOG4108V0P	LemA family
HB751_RS09260	ENOG4105D0M	Protease HtpX homolog
HB751_RS09265	ENOG4105D60	lipoprotein releasing system transmembrane protein
HB751_RS09270	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HB751_RS09285	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HB751_RS09290	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HB751_RS09305	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HB751_RS09315	ENOG4105DQR	SNARE associated Golgi
HB751_RS09395	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HB751_RS09415	ENOG4108JJA	ABC, transporter
HB751_RS09420	ENOG4105F3R	pts system mannose fructose sorbose family iid
HB751_RS09425	ENOG4105ETZ	PTS System
HB751_RS09440	ENOG4105C7H	Helicase, RecD TraA family
HB751_RS09445	ENOG4105C3F	Signal peptidase i
HB751_RS09450	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HB751_RS09470	ENOG4105C98	muts2 protein
HB751_RS09475	ENOG4105K63	Thioredoxin
HB751_RS09480	ENOG4105E2A	Dehydrogenase
HB751_RS09500	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HB751_RS09505	ENOG4108UUM	single-stranded DNA-binding protein
HB751_RS09510	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HB751_RS09545	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HB751_RS09550	ENOG4105DC7	peptidase M24
HB751_RS09555	ENOG4108UK2	deaminase
HB751_RS09560	ENOG4105EYW	Ion transport protein
HB751_RS09675	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HB751_RS09680	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HB751_RS09790	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HB751_RS09800	ENOG4105M7K	Involved in the transcription termination process (By similarity)
HB751_RS09805	ENOG4105ETE	Transcriptional regulator (LacI family
HB751_RS09815	ENOG4105C5Y	PTS System
HB751_RS09820	ENOG4105EVU	fructokinase
HB751_RS09825	ENOG4105DG6	mannose-6-phosphate isomerase
HB751_RS09830	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HB751_RS09835	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HB751_RS09840	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HB751_RS09845	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HB751_RS09850	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HB751_RS09855	ENOG4105CB5	ATP-dependent DNA helicase recG
HB751_RS09865	ENOG4107RB3	L-asparaginase
HB751_RS09870	ENOG410667J	hydrolase
HB751_RS09880	ENOG41080Y5	BioY family
HB751_RS09885	ENOG4105CHM	Aminotransferase
HB751_RS09890	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
HB751_RS09905	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HB751_RS09910	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HB751_RS09915	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HB751_RS09930	ENOG4108KXV	response regulator
HB751_RS09995	ENOG4108UZ3	Transporter
HB751_RS10000	ENOG41087PP	glycosyltransferase MGT family
HB751_RS10005	ENOG4105YA8	Transcriptional regulator
HB751_RS10015	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HB751_RS10020	ENOG4105CQW	ribosome biogenesis GTPase YqeH
HB751_RS10025	ENOG410812S	Rna-binding protein
HB751_RS10030	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HB751_RS10035	ENOG4108WF2	Metal Dependent Phosphohydrolase
HB751_RS10040	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HB751_RS10045	ENOG4105DXX	methyltransferase
HB751_RS10060	ENOG4105CDE	UPF0348 protein
HB751_RS10065	ENOG4105E4P	ATPase (AAA
HB751_RS10075	ENOG4107TXC	Transcriptional regulator
HB751_RS10085	ENOG4105VIE	preprotein translocase, subunit YajC
HB751_RS10090	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HB751_RS10095	ENOG4105KNE	Phosphatidate cytidylyltransferase
HB751_RS10105	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HB751_RS10165	ENOG4105EVI	UPF0374 protein
HB751_RS10170	ENOG410902V	Modulates RecA activity (By similarity)
HB751_RS10175	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HB751_RS10180	ENOG4105MTF	NrdI protein
HB751_RS10230	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)