locus-tag	class	description
FSA31_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSA31_RS00010	COG0592	DNA-directed DNA polymerase activity
FSA31_RS00020	COG0012	GTP binding
FSA31_RS00025	COG0193	aminoacyl-tRNA hydrolase activity
FSA31_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FSA31_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FSA31_RS00055	COG0037	tRNA processing
FSA31_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FSA31_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSA31_RS00075	COG0531	amino acid
FSA31_RS00185	COG1792	Involved in formation and maintenance of cell shape
FSA31_RS00195	COG3942	CHAP domain
FSA31_RS00200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSA31_RS00205	COG0436	Aminotransferase
FSA31_RS00210	COG1381	Involved in DNA repair and RecF pathway recombination
FSA31_RS00215	COG0416	fatty acid biosynthetic process
FSA31_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSA31_RS00225	COG2274	protein secretion by the type I secretion system
FSA31_RS00230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSA31_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSA31_RS00245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FSA31_RS00250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSA31_RS00255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FSA31_RS00260	COG2176	DNA-directed DNA polymerase activity
FSA31_RS00270	COG0138	bifunctional purine biosynthesis protein purh
FSA31_RS00290	COG0653	protein targeting
FSA31_RS00300	COG0151	Belongs to the GarS family
FSA31_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FSA31_RS00330	COG1794	racemase activity, acting on amino acids and derivatives
FSA31_RS00345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSA31_RS00365	COG2255	four-way junction helicase activity
FSA31_RS00370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSA31_RS00405	COG0534	Mate efflux family protein
FSA31_RS00415	COG3830	Belongs to the UPF0237 family
FSA31_RS00420	COG2848	UPF0210 protein
FSA31_RS00435	COG1705	Flagellar rod assembly protein muramidase FlgJ
FSA31_RS00445	COG5492	domain, Protein
FSA31_RS00445	COG3583	domain protein
FSA31_RS00445	COG1621	beta-fructofuranosidase activity
FSA31_RS00455	COG1420	regulation of RNA biosynthetic process
FSA31_RS00460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FSA31_RS00470	COG0443	Heat shock 70 kDa protein
FSA31_RS00475	COG0484	heat shock protein binding
FSA31_RS00480	COG0101	tRNA pseudouridine synthase activity
FSA31_RS00485	COG0351	phosphomethylpyrimidine kinase
FSA31_RS00490	COG4720	Psort location CytoplasmicMembrane, score
FSA31_RS00495	COG4475	Protein of unknown function (DUF436)
FSA31_RS00500	COG0668	transmembrane transport
FSA31_RS00510	COG0544	peptidyl-prolyl cis-trans isomerase activity
FSA31_RS00520	COG2226	methyltransferase
FSA31_RS00525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FSA31_RS00530	COG1854	S-ribosylhomocysteine lyase activity
FSA31_RS00535	COG0697	spore germination
FSA31_RS00540	COG1959	2 iron, 2 sulfur cluster binding
FSA31_RS00545	COG2223	nitrite transmembrane transporter activity
FSA31_RS00575	COG3343	RNA polymerase activity
FSA31_RS00580	COG0504	CTP synthase activity
FSA31_RS00600	COG1396	sequence-specific DNA binding
FSA31_RS00635	COG0191	fructose-bisphosphate aldolase activity
FSA31_RS00665	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FSA31_RS00670	COG0534	Mate efflux family protein
FSA31_RS00675	COG2176	DNA-directed DNA polymerase activity
FSA31_RS00680	COG1846	Transcriptional regulator
FSA31_RS00685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FSA31_RS00690	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSA31_RS00695	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSA31_RS00695	COG0022	dehydrogenase e1 component
FSA31_RS00710	COG0095	Lipoate-protein ligase
FSA31_RS00730	COG2856	Zn peptidase
FSA31_RS00740	COG1473	amidohydrolase
FSA31_RS00745	COG0477	Major facilitator Superfamily
FSA31_RS00750	COG1309	transcriptional regulator
FSA31_RS00755	COG0583	DNA-binding transcription factor activity
FSA31_RS00765	COG0281	malic enzyme
FSA31_RS00770	COG0679	Auxin Efflux Carrier
FSA31_RS00775	COG2140	Oxalate decarboxylase
FSA31_RS00790	COG0242	peptide deformylase activity
FSA31_RS00795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSA31_RS00805	COG1454	alcohol dehydrogenase
FSA31_RS00805	COG1012	belongs to the aldehyde dehydrogenase family
FSA31_RS00810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSA31_RS00815	COG1185	polyribonucleotide nucleotidyltransferase activity
FSA31_RS00825	COG1045	serine acetyltransferase
FSA31_RS00830	COG0215	cysteine-tRNA ligase activity
FSA31_RS00835	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FSA31_RS00840	COG5504	Zn-dependent protease
FSA31_RS00860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSA31_RS00880	COG1476	TRANSCRIPTIONal
FSA31_RS00890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FSA31_RS00895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSA31_RS00940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSA31_RS00940	COG3321	synthase
FSA31_RS00940	COG1028	Short-chain dehydrogenase reductase Sdr
FSA31_RS00940	COG4221	oxidoreductase activity
FSA31_RS00945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSA31_RS00960	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FSA31_RS00990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA31_RS01000	COG0431	NADPH-dependent FMN reductase
FSA31_RS01000	COG1053	succinate dehydrogenase
FSA31_RS01000	COG3976	FMN-binding domain protein
FSA31_RS01005	COG0431	NADPH-dependent FMN reductase
FSA31_RS01005	COG1053	succinate dehydrogenase
FSA31_RS01005	COG3976	FMN-binding domain protein
FSA31_RS01010	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FSA31_RS01025	COG0803	Belongs to the bacterial solute-binding protein 9 family
FSA31_RS01035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSA31_RS01040	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FSA31_RS01160	COG1461	Dihydroxyacetone kinase
FSA31_RS01165	COG0028	Belongs to the TPP enzyme family
FSA31_RS01170	COG0440	acetolactate synthase activity
FSA31_RS01175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FSA31_RS01180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FSA31_RS01190	COG1309	transcriptional regulator
FSA31_RS01200	COG1131	(ABC) transporter
FSA31_RS01210	COG1126	abc transporter atp-binding protein
FSA31_RS01215	COG0765	amino acid transport
FSA31_RS01225	COG1968	undecaprenyl-diphosphatase activity
FSA31_RS01230	COG4862	establishment of competence for transformation
FSA31_RS01235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSA31_RS01245	COG0719	Fe-S assembly protein
FSA31_RS01250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FSA31_RS01260	COG0719	Fe-S assembly protein
FSA31_RS01275	COG4166	transmembrane transport
FSA31_RS01280	COG0601	transmembrane transport
FSA31_RS01285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSA31_RS01290	COG0444	Belongs to the ABC transporter superfamily
FSA31_RS01295	COG4608	Belongs to the ABC transporter superfamily
FSA31_RS01305	COG2918	glutathione biosynthetic process
FSA31_RS01305	COG1181	Belongs to the D-alanine--D-alanine ligase family
FSA31_RS01310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSA31_RS01315	COG3037	sugar-specific permease SgaT UlaA
FSA31_RS01325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA31_RS01335	COG3623	hexulose-6-phosphate isomerase
FSA31_RS01385	COG2274	protein secretion by the type I secretion system
FSA31_RS01400	COG3711	transcriptional antiterminator
FSA31_RS01400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA31_RS01430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FSA31_RS01475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FSA31_RS01475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FSA31_RS01480	COG1832	CoA-binding protein
FSA31_RS01490	COG0343	queuine tRNA-ribosyltransferase activity
FSA31_RS01505	COG1234	tRNA 3'-trailer cleavage
FSA31_RS01535	COG0166	Belongs to the GPI family
FSA31_RS01545	COG3711	transcriptional antiterminator
FSA31_RS01545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA31_RS01555	COG3730	PTS system glucitol sorbitol-specific
FSA31_RS01560	COG3732	PTS system glucitol sorbitol-specific
FSA31_RS01575	COG2171	N-acyltransferase activity
FSA31_RS01580	COG1473	amidohydrolase
FSA31_RS01585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSA31_RS01590	COG0457	Tetratricopeptide repeat
FSA31_RS01590	COG0705	Rhomboid family
FSA31_RS01595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FSA31_RS01600	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FSA31_RS01605	COG0756	dUTP diphosphatase activity
FSA31_RS01630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSA31_RS01635	COG1827	regulation of RNA biosynthetic process
FSA31_RS01650	COG0137	argininosuccinate synthase activity
FSA31_RS01655	COG0165	Argininosuccinate lyase
FSA31_RS01660	COG0594	ribonuclease P activity
FSA31_RS01665	COG0706	membrane insertase activity
FSA31_RS01680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FSA31_RS01685	COG0084	hydrolase, TatD family'
FSA31_RS01720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSA31_RS01740	COG1162	GTPase activity
FSA31_RS01765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSA31_RS01775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSA31_RS01780	COG0049	tRNA binding
FSA31_RS01785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FSA31_RS01795	COG0126	phosphoglycerate kinase activity
FSA31_RS01805	COG0789	Transcriptional regulator
FSA31_RS01810	COG0174	glutamine synthetase
FSA31_RS01815	COG0067	glutamate synthase
FSA31_RS01815	COG0069	glutamate synthase activity
FSA31_RS01815	COG0070	glutamate synthase
FSA31_RS01820	COG0493	'glutamate synthase
FSA31_RS01825	COG3942	CHAP domain
FSA31_RS01835	COG5503	Protein of unknown function (DUF1447)
FSA31_RS01855	COG0667	Aldo Keto reductase
FSA31_RS01860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSA31_RS01870	COG1214	PFAM Peptidase M22, glycoprotease
FSA31_RS01875	COG0456	acetyltransferase
FSA31_RS01880	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FSA31_RS01900	COG2081	HI0933 family
FSA31_RS01910	COG0778	Nitroreductase
FSA31_RS01915	COG1733	regulation of RNA biosynthetic process
FSA31_RS01920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FSA31_RS01925	COG2936	dipeptidyl-peptidase activity
FSA31_RS01940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FSA31_RS01950	COG1882	Formate acetyltransferase
FSA31_RS01955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSA31_RS01970	COG0561	phosphatase activity
FSA31_RS01980	COG2252	PERMEase
FSA31_RS01985	COG0802	atpase or kinase
FSA31_RS01990	COG1316	TRANSCRIPTIONal
FSA31_RS02000	COG0537	adenosine 5'-monophosphoramidase activity
FSA31_RS02005	COG1131	(ABC) transporter
FSA31_RS02010	COG4473	ABC transporter
FSA31_RS02020	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FSA31_RS02030	COG0779	Required for maturation of 30S ribosomal subunits
FSA31_RS02035	COG0195	Participates in both transcription termination and antitermination
FSA31_RS02040	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FSA31_RS02050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FSA31_RS02055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSA31_RS02070	COG2217	Heavy metal translocating P-type atpase
FSA31_RS02080	COG0561	phosphatase activity
FSA31_RS02090	COG1131	(ABC) transporter
FSA31_RS02120	COG1924	4 iron, 4 sulfur cluster binding
FSA31_RS02140	COG1673	EVE domain
FSA31_RS02150	COG0752	glycyl-tRNA synthetase alpha subunit
FSA31_RS02155	COG0751	glycine-tRNA ligase activity
FSA31_RS02160	COG4224	UPF0291 protein
FSA31_RS02170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FSA31_RS02175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FSA31_RS02185	COG0275	rRNA processing
FSA31_RS02190	COG4839	cell division protein FtsL
FSA31_RS02195	COG0768	penicillin binding
FSA31_RS02200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSA31_RS02205	COG0513	Belongs to the DEAD box helicase family
FSA31_RS02220	COG1126	abc transporter atp-binding protein
FSA31_RS02230	COG0492	ferredoxin-NADP+ reductase activity
FSA31_RS02235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FSA31_RS02240	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSA31_RS02250	COG3579	cysteine-type endopeptidase activity
FSA31_RS02255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSA31_RS02260	COG3331	DNA recombination
FSA31_RS02265	COG4474	Belongs to the UPF0398 family
FSA31_RS02270	COG3599	regulation of cell shape
FSA31_RS02280	COG0116	Belongs to the methyltransferase superfamily
FSA31_RS02290	COG1854	S-ribosylhomocysteine lyase activity
FSA31_RS02295	COG1418	mRNA catabolic process
FSA31_RS02295	COG4372	Transposase
FSA31_RS02300	COG0194	GDP metabolic process
FSA31_RS02305	COG1758	RNA polymerase activity
FSA31_RS02310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSA31_RS02315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FSA31_RS02320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSA31_RS02320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSA31_RS02340	COG4585	Histidine kinase
FSA31_RS02345	COG2197	response regulator
FSA31_RS02355	COG1098	S1 RNA binding domain
FSA31_RS02360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FSA31_RS02365	COG1349	DNA-binding transcription factor activity
FSA31_RS02370	COG1882	Formate acetyltransferase
FSA31_RS02390	COG1739	Uncharacterized protein family UPF0029
FSA31_RS02395	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FSA31_RS02400	COG1040	competence protein
FSA31_RS02445	COG1349	DNA-binding transcription factor activity
FSA31_RS02450	COG0561	phosphatase activity
FSA31_RS02465	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FSA31_RS02490	COG4716	Myosin-crossreactive antigen
FSA31_RS02495	COG0742	ribosomal rna small subunit methyltransferase
FSA31_RS02500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FSA31_RS02505	COG3480	Lon protease (S16) C-terminal proteolytic domain
FSA31_RS02510	COG0737	Belongs to the 5'-nucleotidase family
FSA31_RS02515	COG4470	Protein conserved in bacteria
FSA31_RS02520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FSA31_RS02530	COG1132	(ABC) transporter
FSA31_RS02535	COG1132	(ABC) transporter
FSA31_RS02550	COG3804	dihydrodipicolinate reductase
FSA31_RS02570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FSA31_RS02575	COG0512	Glutamine amidotransferase of anthranilate synthase
FSA31_RS02580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FSA31_RS02585	COG0134	indole-3-glycerol-phosphate synthase activity
FSA31_RS02590	COG0135	phosphoribosylanthranilate isomerase activity
FSA31_RS02595	COG0133	tryptophan synthase activity
FSA31_RS02600	COG0159	tryptophan synthase activity
FSA31_RS02610	COG0783	Belongs to the Dps family
FSA31_RS02620	COG1940	carbohydrate kinase activity
FSA31_RS02625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FSA31_RS02635	COG1217	gtp-binding protein TYPA
FSA31_RS02645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FSA31_RS02650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FSA31_RS02660	COG0849	cell division
FSA31_RS02670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FSA31_RS02675	COG1799	cell septum assembly
FSA31_RS02685	COG2302	S4 RNA-binding domain
FSA31_RS02690	COG3599	regulation of cell shape
FSA31_RS02695	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSA31_RS02710	COG0542	response to heat
FSA31_RS02715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FSA31_RS02720	COG4703	Protein of unknown function (DUF1797)
FSA31_RS02725	COG0765	amino acid transport
FSA31_RS02730	COG1126	abc transporter atp-binding protein
FSA31_RS02750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSA31_RS02755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSA31_RS02760	COG1346	cytolysis
FSA31_RS02765	COG1380	Effector of murein hydrolase LrgA
FSA31_RS02770	COG3279	Response regulator of the LytR AlgR family
FSA31_RS02775	COG3275	phosphorelay sensor kinase activity
FSA31_RS02780	COG1570	exodeoxyribonuclease VII activity
FSA31_RS02785	COG1722	exodeoxyribonuclease VII activity
FSA31_RS02795	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FSA31_RS02800	COG1438	arginine binding
FSA31_RS02805	COG0497	DNA recombination
FSA31_RS02810	COG1307	EDD domain protein, DegV family
FSA31_RS02815	COG2755	lipolytic protein G-D-S-L family
FSA31_RS02825	COG0776	regulation of translation
FSA31_RS02830	COG2801	Transposase and inactivated derivatives
FSA31_RS02845	COG0735	belongs to the Fur family
FSA31_RS02860	COG0588	phosphoglycerate mutase activity
FSA31_RS02865	COG0768	penicillin binding
FSA31_RS02870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSA31_RS02875	COG1181	Belongs to the D-alanine--D-alanine ligase family
FSA31_RS02885	COG0385	Bile acid
FSA31_RS02890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSA31_RS02910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FSA31_RS02920	COG3064	Membrane
FSA31_RS02920	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FSA31_RS02925	COG0513	Belongs to the DEAD box helicase family
FSA31_RS02960	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FSA31_RS02970	COG0726	polysaccharide deacetylase
FSA31_RS02975	COG0204	Acyl-transferase
FSA31_RS02980	COG1555	photosystem II stabilization
FSA31_RS02980	COG1596	polysaccharide export
FSA31_RS02985	COG2333	competence protein COMEC
FSA31_RS02985	COG0658	competence protein
FSA31_RS03000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSA31_RS03025	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSA31_RS03035	COG0363	glucosamine-6-phosphate deaminase activity
FSA31_RS03045	COG1187	pseudouridine synthase activity
FSA31_RS03055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSA31_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
FSA31_RS03060	COG0604	alcohol dehydrogenase
FSA31_RS03060	COG3321	synthase
FSA31_RS03095	COG0131	Imidazoleglycerol-phosphate dehydratase
FSA31_RS03095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FSA31_RS03100	COG4122	O-methyltransferase activity
FSA31_RS03105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSA31_RS03115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FSA31_RS03165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FSA31_RS03170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSA31_RS03175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSA31_RS03180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSA31_RS03190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSA31_RS03195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FSA31_RS03200	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FSA31_RS03205	COG0372	Belongs to the citrate synthase family
FSA31_RS03210	COG0538	isocitrate dehydrogenase activity
FSA31_RS03225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA31_RS03230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FSA31_RS03235	COG1012	belongs to the aldehyde dehydrogenase family
FSA31_RS03240	COG0789	Transcriptional regulator
FSA31_RS03245	COG0656	L-ascorbic acid biosynthetic process
FSA31_RS03250	COG0656	L-ascorbic acid biosynthetic process
FSA31_RS03275	COG2195	Cleaves the N-terminal amino acid of tripeptides
FSA31_RS03295	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FSA31_RS03300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FSA31_RS03305	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FSA31_RS03310	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FSA31_RS03315	COG0406	alpha-ribazole phosphatase activity
FSA31_RS03325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FSA31_RS03340	COG3859	Proton-coupled thiamine transporter YuaJ
FSA31_RS03360	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FSA31_RS03370	COG0772	Belongs to the SEDS family
FSA31_RS03375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSA31_RS03405	COG2274	protein secretion by the type I secretion system
FSA31_RS03410	COG0149	triose-phosphate isomerase activity
FSA31_RS03420	COG2348	transferase activity, transferring amino-acyl groups
FSA31_RS03430	COG1078	dGTPase activity
FSA31_RS03455	COG0584	glycerophosphoryl diester phosphodiesterase
FSA31_RS03470	COG0604	alcohol dehydrogenase
FSA31_RS03530	COG0561	phosphatase activity
FSA31_RS03535	COG0561	phosphatase activity
FSA31_RS03540	COG0552	protein localization to endoplasmic reticulum
FSA31_RS03545	COG0477	Major facilitator Superfamily
FSA31_RS03550	COG3689	TIGRFAM TIGR03943 family protein
FSA31_RS03555	COG0701	Predicted permease
FSA31_RS03565	COG2183	response to ionizing radiation
FSA31_RS03570	COG3091	SprT-like family
FSA31_RS03580	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FSA31_RS03585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FSA31_RS03610	COG0826	peptidase U32
FSA31_RS03615	COG0450	alkyl hydroperoxide reductase
FSA31_RS03630	COG4443	Transcriptional Coactivator p15 (PC4)
FSA31_RS03635	COG1914	H( )-stimulated, divalent metal cation uptake system
FSA31_RS03645	COG0366	Alpha amylase catalytic
FSA31_RS03645	COG5263	repeat protein
FSA31_RS03650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FSA31_RS03670	COG1368	sulfuric ester hydrolase activity
FSA31_RS03675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FSA31_RS03680	COG0710	3-dehydroquinate dehydratase activity
FSA31_RS03685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FSA31_RS03690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FSA31_RS03695	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FSA31_RS03700	COG0287	Prephenate dehydrogenase
FSA31_RS03705	COG3679	Belongs to the UPF0342 family
FSA31_RS03710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSA31_RS03715	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FSA31_RS03720	COG0077	Prephenate dehydratase
FSA31_RS03730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FSA31_RS03790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FSA31_RS03800	COG0488	(ABC) transporter
FSA31_RS03805	COG1126	abc transporter atp-binding protein
FSA31_RS03820	COG0556	nucleotide-excision repair
FSA31_RS03845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA31_RS03855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA31_RS03865	COG1970	mechanosensitive ion channel activity
FSA31_RS03875	COG0358	DNA primase activity
FSA31_RS03880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSA31_RS03885	COG2151	metal-sulfur cluster biosynthetic enzyme
FSA31_RS03895	COG1091	dTDP-4-dehydrorhamnose reductase activity
FSA31_RS03930	COG1368	sulfuric ester hydrolase activity
FSA31_RS03940	COG0463	Glycosyl transferase, family 2
FSA31_RS03955	COG3942	CHAP domain
FSA31_RS03960	COG0656	L-ascorbic acid biosynthetic process
FSA31_RS03965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSA31_RS03970	COG0285	dihydrofolate synthase activity
FSA31_RS03980	COG1104	cysteine desulfurase activity
FSA31_RS03985	COG0301	tRNA thio-modification
FSA31_RS04010	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FSA31_RS04020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FSA31_RS04030	COG2816	NAD+ diphosphatase activity
FSA31_RS04035	COG0583	DNA-binding transcription factor activity
FSA31_RS04040	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FSA31_RS04045	COG0564	pseudouridine synthase activity
FSA31_RS04055	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FSA31_RS04065	COG0540	Belongs to the ATCase OTCase family
FSA31_RS04070	COG0505	Belongs to the CarA family
FSA31_RS04075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSA31_RS04085	COG1136	(ABC) transporter
FSA31_RS04090	COG0577	efflux transmembrane transporter activity
FSA31_RS04095	COG0228	four-way junction DNA binding
FSA31_RS04100	COG1837	Belongs to the UPF0109 family
FSA31_RS04105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSA31_RS04110	COG0336	Belongs to the RNA methyltransferase TrmD family
FSA31_RS04115	COG0492	ferredoxin-NADP+ reductase activity
FSA31_RS04120	COG1349	DNA-binding transcription factor activity
FSA31_RS04125	COG1105	Belongs to the carbohydrate kinase PfkB family
FSA31_RS04130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FSA31_RS04130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA31_RS04130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FSA31_RS04135	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FSA31_RS04140	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FSA31_RS04140	COG0646	methionine synthase
FSA31_RS04155	COG2207	Transcriptional regulator
FSA31_RS04160	COG3345	alpha-galactosidase
FSA31_RS04165	COG1653	transport
FSA31_RS04170	COG1175	transmembrane transport
FSA31_RS04175	COG0395	ABC-type sugar transport system, permease component
FSA31_RS04180	COG0366	Alpha amylase catalytic
FSA31_RS04185	COG3842	ATPase activity
FSA31_RS04190	COG0366	Alpha amylase catalytic
FSA31_RS04195	COG1609	Transcriptional regulator
FSA31_RS04200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FSA31_RS04205	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FSA31_RS04210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSA31_RS04230	COG1131	(ABC) transporter
FSA31_RS04245	COG1307	EDD domain protein, DegV family
FSA31_RS04250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FSA31_RS04255	COG0617	tRNA 3'-terminal CCA addition
FSA31_RS04280	COG0366	Alpha amylase catalytic
FSA31_RS04280	COG5263	repeat protein
FSA31_RS04290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSA31_RS04300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FSA31_RS04305	COG0602	queuosine metabolic process
FSA31_RS04315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FSA31_RS04330	COG1132	(ABC) transporter
FSA31_RS04335	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FSA31_RS04345	COG2357	RelA SpoT domain protein
FSA31_RS04350	COG0745	RESPONSE REGULATOR receiver
FSA31_RS04360	COG3759	membrane
FSA31_RS04365	COG0583	DNA-binding transcription factor activity
FSA31_RS04375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA31_RS04380	COG0765	amino acid transport
FSA31_RS04385	COG0765	amino acid transport
FSA31_RS04390	COG1126	abc transporter atp-binding protein
FSA31_RS04405	COG1304	FMN binding
FSA31_RS04410	COG1272	protein, Hemolysin III
FSA31_RS04425	COG3425	synthase
FSA31_RS04430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FSA31_RS04435	COG3201	nicotinamide mononucleotide transporter
FSA31_RS04440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FSA31_RS04450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FSA31_RS04455	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FSA31_RS04460	COG0833	amino acid
FSA31_RS04465	COG2040	homocysteine
FSA31_RS04470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSA31_RS04495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FSA31_RS04500	COG0222	ribosome binding
FSA31_RS04510	COG1960	acyl-CoA dehydrogenase activity
FSA31_RS04515	COG0726	polysaccharide deacetylase
FSA31_RS04525	COG0083	homoserine kinase activity
FSA31_RS04530	COG0285	dihydrofolate synthase activity
FSA31_RS04535	COG0302	gtp cyclohydrolase
FSA31_RS04555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FSA31_RS04560	COG3842	ATPase activity
FSA31_RS04565	COG1176	ABC-type spermidine putrescine transport system, permease component I
FSA31_RS04570	COG1177	transmembrane transport
FSA31_RS04575	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FSA31_RS04605	COG4932	domain protein
FSA31_RS04610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSA31_RS04620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FSA31_RS04625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSA31_RS04640	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FSA31_RS04645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSA31_RS04650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FSA31_RS04655	COG4605	iron ion homeostasis
FSA31_RS04660	COG4604	ABC transporter, ATP-binding protein
FSA31_RS04665	COG4607	ABC-type enterochelin transport system periplasmic component
FSA31_RS04680	COG0758	DNA mediated transformation
FSA31_RS04685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FSA31_RS04690	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FSA31_RS04695	COG5263	repeat protein
FSA31_RS04695	COG0366	Alpha amylase catalytic
FSA31_RS04700	COG0366	Alpha amylase catalytic
FSA31_RS04700	COG5263	repeat protein
FSA31_RS04705	COG1136	(ABC) transporter
FSA31_RS04715	COG0745	RESPONSE REGULATOR receiver
FSA31_RS04720	COG0642	Histidine kinase
FSA31_RS04725	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FSA31_RS04730	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FSA31_RS04740	COG2851	Citrate transporter
FSA31_RS04750	COG0511	ligase activity, forming carbon-carbon bonds
FSA31_RS04755	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FSA31_RS04760	COG3052	prosthetic group binding
FSA31_RS04785	COG2801	Transposase and inactivated derivatives
FSA31_RS04790	COG4974	Belongs to the 'phage' integrase family
FSA31_RS04795	COG1131	(ABC) transporter
FSA31_RS04810	COG0745	RESPONSE REGULATOR receiver
FSA31_RS04815	COG1442	glycosyl transferase family 8
FSA31_RS04820	COG4221	oxidoreductase activity
FSA31_RS04825	COG1131	(ABC) transporter
FSA31_RS04835	COG0280	phosphate acetyltransferase
FSA31_RS04840	COG0564	pseudouridine synthase activity
FSA31_RS04845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSA31_RS04850	COG2357	RelA SpoT domain protein
FSA31_RS04865	COG4116	CYTH
FSA31_RS04870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSA31_RS04875	COG1104	cysteine desulfurase activity
FSA31_RS04885	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FSA31_RS04890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FSA31_RS04920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSA31_RS04925	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FSA31_RS04935	COG3448	diguanylate cyclase activity
FSA31_RS04935	COG4175	Glycine betaine
FSA31_RS04945	COG2188	Transcriptional regulator
FSA31_RS04950	COG0519	Catalyzes the synthesis of GMP from XMP
FSA31_RS04960	COG1131	(ABC) transporter
FSA31_RS04980	COG1247	-acetyltransferase
FSA31_RS04985	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FSA31_RS04995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FSA31_RS05000	COG4684	Psort location CytoplasmicMembrane, score
FSA31_RS05005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSA31_RS05010	COG1132	(ABC) transporter
FSA31_RS05015	COG1132	(ABC) transporter
FSA31_RS05030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FSA31_RS05035	COG0009	L-threonylcarbamoyladenylate synthase
FSA31_RS05040	COG2890	protein-(glutamine-N5) methyltransferase activity
FSA31_RS05045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSA31_RS05050	COG1435	thymidine kinase activity
FSA31_RS05055	COG1942	4-Oxalocrotonate Tautomerase
FSA31_RS05070	COG3976	FMN-binding domain protein
FSA31_RS05070	COG1053	succinate dehydrogenase
FSA31_RS05070	COG0431	NADPH-dependent FMN reductase
FSA31_RS05080	COG0577	efflux transmembrane transporter activity
FSA31_RS05090	COG1174	glycine betaine transport
FSA31_RS05105	COG1063	alcohol dehydrogenase
FSA31_RS05110	COG0628	permease
FSA31_RS05115	COG2723	6-phospho-beta-galactosidase activity
FSA31_RS05125	COG0406	alpha-ribazole phosphatase activity
FSA31_RS05145	COG0561	phosphatase activity
FSA31_RS05165	COG0346	lactoylglutathione lyase activity
FSA31_RS05170	COG3764	Sortase (surface protein transpeptidase)
FSA31_RS05180	COG0039	L-malate dehydrogenase activity
FSA31_RS05195	COG1079	Belongs to the binding-protein-dependent transport system permease family
FSA31_RS05200	COG4603	Belongs to the binding-protein-dependent transport system permease family
FSA31_RS05205	COG3845	ABC transporter
FSA31_RS05210	COG1744	ABC transporter substrate-binding protein PnrA-like
FSA31_RS05215	COG0295	cytidine deaminase activity
FSA31_RS05220	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FSA31_RS05225	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FSA31_RS05230	COG2813	Specifically methylates the guanine in position
FSA31_RS05235	COG1072	(Pantothenic acid kinase))
FSA31_RS05240	COG0268	Binds directly to 16S ribosomal RNA
FSA31_RS05245	COG5002	protein histidine kinase activity
FSA31_RS05250	COG0745	RESPONSE REGULATOR receiver
FSA31_RS05265	COG0704	Plays a role in the regulation of phosphate uptake
FSA31_RS05270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSA31_RS05275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSA31_RS05280	COG0581	inorganic phosphate transmembrane transporter activity
FSA31_RS05285	COG0573	inorganic phosphate transmembrane transporter activity
FSA31_RS05295	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FSA31_RS05295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSA31_RS05300	COG0483	inositol monophosphate 1-phosphatase activity
FSA31_RS05305	COG4476	Belongs to the UPF0223 family
FSA31_RS05310	COG1393	Belongs to the ArsC family
FSA31_RS05315	COG0196	riboflavin kinase activity
FSA31_RS05320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSA31_RS05325	COG2205	protein histidine kinase activity
FSA31_RS05330	COG0745	RESPONSE REGULATOR receiver
FSA31_RS05410	COG1132	(ABC) transporter
FSA31_RS05415	COG2375	cellular response to nickel ion
FSA31_RS05415	COG1132	(ABC) transporter
FSA31_RS05440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSA31_RS05445	COG0785	Cytochrome C biogenesis protein
FSA31_RS05460	COG2873	o-acetylhomoserine
FSA31_RS05465	COG0210	DNA helicase
FSA31_RS05470	COG1115	amino acid carrier protein
FSA31_RS05475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FSA31_RS05480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA31_RS05485	COG1126	abc transporter atp-binding protein
FSA31_RS05490	COG0765	amino acid transport
FSA31_RS05495	COG2824	Alkylphosphonate utilization operon protein PhnA
FSA31_RS05500	COG0246	Mannitol dehydrogenase
FSA31_RS05505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA31_RS05510	COG3711	transcriptional antiterminator
FSA31_RS05515	COG2213	PTS system mannitol-specific
FSA31_RS05520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSA31_RS05530	COG2261	transglycosylase associated protein
FSA31_RS05535	COG0469	pyruvate kinase activity
FSA31_RS05540	COG0205	6-phosphofructokinase activity
FSA31_RS05550	COG1725	Transcriptional regulator
FSA31_RS05555	COG1131	(ABC) transporter
FSA31_RS05585	COG0539	negative regulation of cytoplasmic translation
FSA31_RS05605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FSA31_RS05620	COG0187	DNA topoisomerase II activity
FSA31_RS05625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FSA31_RS05630	COG0737	Belongs to the 5'-nucleotidase family
FSA31_RS05640	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FSA31_RS05645	COG0765	amino acid transport
FSA31_RS05650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA31_RS05660	COG2315	Protein conserved in bacteria
FSA31_RS05665	COG1881	PFAM PEBP family protein
FSA31_RS05675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FSA31_RS05680	COG0284	orotidine-5'-phosphate decarboxylase activity
FSA31_RS05685	COG0167	dihydroorotate dehydrogenase activity
FSA31_RS05690	COG0543	2 iron, 2 sulfur cluster binding
FSA31_RS05705	COG0813	purine-nucleoside phosphorylase activity
FSA31_RS05735	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FSA31_RS05740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FSA31_RS05745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FSA31_RS05765	COG1573	uracil-dna glycosylase
FSA31_RS05770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FSA31_RS05780	COG0322	excinuclease ABC activity
FSA31_RS05790	COG1011	Hydrolase
FSA31_RS05800	COG0148	phosphopyruvate hydratase activity
FSA31_RS05900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSA31_RS05905	COG0107	imidazoleglycerol-phosphate synthase activity
FSA31_RS05910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FSA31_RS05915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSA31_RS05925	COG0131	Imidazoleglycerol-phosphate dehydratase
FSA31_RS05930	COG0560	Phosphoserine phosphatase
FSA31_RS05935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSA31_RS05940	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSA31_RS05945	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FSA31_RS05950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSA31_RS05960	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FSA31_RS05975	COG0772	Belongs to the SEDS family
FSA31_RS06000	COG2814	Major facilitator Superfamily
FSA31_RS06010	COG0335	large ribosomal subunit rRNA binding
FSA31_RS06015	COG0038	chloride channel
FSA31_RS06020	COG0038	chloride channel
FSA31_RS06025	COG1605	Chorismate mutase
FSA31_RS06025	COG0077	Prephenate dehydratase
FSA31_RS06040	COG0716	FMN binding
FSA31_RS06045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSA31_RS06050	COG0625	glutathione transferase activity
FSA31_RS06055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSA31_RS06060	COG0254	rRNA binding
FSA31_RS06075	COG2226	methyltransferase
FSA31_RS06090	COG1481	regulation of sporulation
FSA31_RS06100	COG1660	Displays ATPase and GTPase activities
FSA31_RS06110	COG0251	oxidation-reduction process
FSA31_RS06115	COG0371	Dehydrogenase
FSA31_RS06125	COG0017	Asparaginyl-tRNA synthetase
FSA31_RS06130	COG0436	Aminotransferase
FSA31_RS06135	COG1199	ATP-dependent helicase activity
FSA31_RS06135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FSA31_RS06175	COG2177	Part of the ABC transporter FtsEX involved in
FSA31_RS06180	COG2884	Cell division ATP-binding protein ftsE
FSA31_RS06190	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FSA31_RS06200	COG2813	Specifically methylates the guanine in position
FSA31_RS06210	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FSA31_RS06210	COG0456	acetyltransferase
FSA31_RS06225	COG0066	3-isopropylmalate dehydratase activity
FSA31_RS06230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSA31_RS06235	COG0473	3-isopropylmalate dehydrogenase activity
FSA31_RS06245	COG0572	uridine kinase
FSA31_RS06250	COG0673	inositol 2-dehydrogenase activity
FSA31_RS06260	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FSA31_RS06285	COG0481	GTPase activity
FSA31_RS06310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSA31_RS06325	COG3976	FMN-binding domain protein
FSA31_RS06325	COG1053	succinate dehydrogenase
FSA31_RS06335	COG1136	(ABC) transporter
FSA31_RS06335	COG0577	efflux transmembrane transporter activity
FSA31_RS06345	COG0647	UMP catabolic process
FSA31_RS06350	COG1051	belongs to the nudix hydrolase family
FSA31_RS06360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSA31_RS06370	COG2249	NAD(P)H dehydrogenase (quinone) activity
FSA31_RS06375	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSA31_RS06380	COG0022	dehydrogenase e1 component
FSA31_RS06385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSA31_RS06395	COG0542	response to heat
FSA31_RS06400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSA31_RS06410	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FSA31_RS06415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSA31_RS06420	COG3442	glutamine amidotransferase
FSA31_RS06425	COG0488	(ABC) transporter
FSA31_RS06435	COG1215	transferase activity, transferring glycosyl groups
FSA31_RS06450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FSA31_RS06460	COG4808	Protein conserved in bacteria
FSA31_RS06485	COG3842	ATPase activity
FSA31_RS06500	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FSA31_RS06505	COG1113	amino acid transport
FSA31_RS06510	COG3527	Alpha-acetolactate decarboxylase
FSA31_RS06515	COG0028	Belongs to the TPP enzyme family
FSA31_RS06525	COG0628	permease
FSA31_RS06530	COG1051	belongs to the nudix hydrolase family
FSA31_RS06540	COG1088	dTDP-glucose 4,6-dehydratase activity
FSA31_RS06555	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FSA31_RS06565	COG2384	SAM-dependent methyltransferase
FSA31_RS06575	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FSA31_RS06580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSA31_RS06595	COG2378	regulation of single-species biofilm formation
FSA31_RS06600	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FSA31_RS06600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FSA31_RS06605	COG0300	oxidoreductase activity
FSA31_RS06610	COG1234	tRNA 3'-trailer cleavage
FSA31_RS06620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSA31_RS06625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FSA31_RS06655	COG1401	restriction endodeoxyribonuclease activity
FSA31_RS06685	COG2723	6-phospho-beta-galactosidase activity
FSA31_RS06690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA31_RS06690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA31_RS06695	COG1447	Phosphotransferase system cellobiose-specific component IIA
FSA31_RS06700	COG3775	system Galactitol-specific IIC component
FSA31_RS06715	COG3684	Belongs to the aldolase LacD family
FSA31_RS06720	COG1105	Belongs to the carbohydrate kinase PfkB family
FSA31_RS06725	COG0698	ribose 5-phosphate isomerase
FSA31_RS06730	COG0698	ribose 5-phosphate isomerase
FSA31_RS06735	COG1349	DNA-binding transcription factor activity
FSA31_RS06740	COG1074	ATP-dependent DNA helicase activity
FSA31_RS06745	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FSA31_RS06760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA31_RS06760	COG0072	phenylalanine-tRNA ligase activity
FSA31_RS06775	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSA31_RS06780	COG1396	sequence-specific DNA binding
FSA31_RS06785	COG0072	phenylalanine-tRNA ligase activity
FSA31_RS06785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA31_RS06790	COG0456	acetyltransferase
FSA31_RS06795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FSA31_RS06800	COG1196	nuclear chromosome segregation
FSA31_RS06805	COG0571	ribonuclease III activity
FSA31_RS06810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FSA31_RS06815	COG5002	protein histidine kinase activity
FSA31_RS06820	COG0745	RESPONSE REGULATOR receiver
FSA31_RS06825	COG1126	abc transporter atp-binding protein
FSA31_RS06830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA31_RS06835	COG0765	amino acid transport
FSA31_RS06840	COG0765	amino acid transport
FSA31_RS06855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FSA31_RS06865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FSA31_RS06870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSA31_RS06875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FSA31_RS06880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FSA31_RS06885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FSA31_RS06890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FSA31_RS06895	COG0356	it plays a direct role in the translocation of protons across the membrane
FSA31_RS06905	COG0058	SHG alpha-glucan phosphorylase activity
FSA31_RS06910	COG0297	glycogen (starch) synthase activity
FSA31_RS06915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FSA31_RS06920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FSA31_RS06925	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FSA31_RS06930	COG1523	belongs to the glycosyl hydrolase 13 family
FSA31_RS06935	COG1597	lipid kinase activity
FSA31_RS06940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSA31_RS06945	COG4708	membrane
FSA31_RS06955	COG2197	response regulator
FSA31_RS06960	COG4585	Histidine kinase
FSA31_RS06970	COG1131	(ABC) transporter
FSA31_RS06990	COG1295	ribonuclease BN
FSA31_RS07000	COG4109	DRTGG domain
FSA31_RS07020	COG0569	domain protein
FSA31_RS07025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FSA31_RS07030	COG0058	SHG alpha-glucan phosphorylase activity
FSA31_RS07035	COG1640	4-alpha-glucanotransferase
FSA31_RS07040	COG1609	Transcriptional regulator
FSA31_RS07050	COG1175	transmembrane transport
FSA31_RS07055	COG3833	ABC-type maltose transport systems, permease component
FSA31_RS07060	COG3842	ATPase activity
FSA31_RS07065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FSA31_RS07070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSA31_RS07090	COG5290	Psort location Cytoplasmic, score
FSA31_RS07105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FSA31_RS07110	COG1956	GAF domain-containing protein
FSA31_RS07115	COG4716	Myosin-crossreactive antigen
FSA31_RS07125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FSA31_RS07140	COG0438	transferase activity, transferring glycosyl groups
FSA31_RS07155	COG1609	Transcriptional regulator
FSA31_RS07175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA31_RS07185	COG1447	Phosphotransferase system cellobiose-specific component IIA
FSA31_RS07190	COG3711	transcriptional antiterminator
FSA31_RS07190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FSA31_RS07195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FSA31_RS07200	COG2723	6-phospho-beta-galactosidase activity
FSA31_RS07210	COG0778	Nitroreductase
FSA31_RS07215	COG0346	lactoylglutathione lyase activity
FSA31_RS07220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FSA31_RS07225	COG0557	exoribonuclease II activity
FSA31_RS07235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FSA31_RS07240	COG2814	Major facilitator Superfamily
FSA31_RS07245	COG0237	dephospho-CoA kinase activity
FSA31_RS07250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FSA31_RS07265	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSA31_RS07275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FSA31_RS07280	COG1702	phosphate starvation-inducible protein PhoH
FSA31_RS07285	COG4479	Belongs to the UPF0346 family
FSA31_RS07290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSA31_RS07300	COG0233	cytoplasmic translational termination
FSA31_RS07305	COG0528	UMP kinase activity
FSA31_RS07310	COG0081	regulation of translation
FSA31_RS07315	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FSA31_RS07325	COG1674	ftsk spoiiie
FSA31_RS07350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FSA31_RS07370	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA31_RS07370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA31_RS07410	COG0640	Transcriptional regulator
FSA31_RS07420	COG0708	Exodeoxyribonuclease III
FSA31_RS07425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FSA31_RS07430	COG1393	Belongs to the ArsC family
FSA31_RS07435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FSA31_RS07440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSA31_RS07455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FSA31_RS07460	COG0347	Belongs to the P(II) protein family
FSA31_RS07465	COG0004	ammonium transporteR
FSA31_RS07475	COG4467	Involved in initiation control of chromosome replication
FSA31_RS07480	COG1774	PSP1 C-terminal conserved region
FSA31_RS07485	COG0470	DNA polymerase III
FSA31_RS07490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FSA31_RS07495	COG0517	IMP dehydrogenase activity
FSA31_RS07515	COG0559	Belongs to the binding-protein-dependent transport system permease family
FSA31_RS07525	COG4471	UPF0298 protein
FSA31_RS07535	COG0740	serine-type endopeptidase activity
FSA31_RS07540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FSA31_RS07545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FSA31_RS07550	COG0626	cystathionine gamma-synthase activity
FSA31_RS07555	COG2244	polysaccharide biosynthetic process
FSA31_RS07560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSA31_RS07585	COG0693	protein deglycase activity
FSA31_RS07590	COG2378	regulation of single-species biofilm formation
FSA31_RS07600	COG1227	inorganic diphosphatase activity
FSA31_RS07605	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FSA31_RS07610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSA31_RS07615	COG1696	Membrane protein involved in D-alanine export
FSA31_RS07620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSA31_RS07630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FSA31_RS07635	COG1253	flavin adenine dinucleotide binding
FSA31_RS07640	COG0628	permease
FSA31_RS07645	COG1119	ATPase activity
FSA31_RS07650	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FSA31_RS07655	COG1242	4 iron, 4 sulfur cluster binding
FSA31_RS07660	COG1346	cytolysis
FSA31_RS07670	COG0671	phosphoesterase, PA-phosphatase related
FSA31_RS07675	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FSA31_RS07700	COG0569	domain protein
FSA31_RS07705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FSA31_RS07710	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSA31_RS07715	COG1187	pseudouridine synthase activity
FSA31_RS07720	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSA31_RS07725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSA31_RS07730	COG0582	viral genome integration into host DNA
FSA31_RS07745	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FSA31_RS07750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSA31_RS07755	COG3763	UPF0154 protein
FSA31_RS07760	COG0019	diaminopimelate decarboxylase activity
FSA31_RS07775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSA31_RS07780	COG1254	Belongs to the acylphosphatase family
FSA31_RS07785	COG0706	membrane insertase activity
FSA31_RS07790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSA31_RS07795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSA31_RS07805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSA31_RS07815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FSA31_RS07830	COG0439	Biotin carboxylase
FSA31_RS07835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FSA31_RS07845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSA31_RS07850	COG1028	Short-chain dehydrogenase reductase Sdr
FSA31_RS07855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FSA31_RS07870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSA31_RS07875	COG1846	Transcriptional regulator
FSA31_RS07880	COG1024	Enoyl-CoA hydratase
FSA31_RS07885	COG0546	phosphoglycolate phosphatase activity
FSA31_RS07890	COG0527	aspartate kinase activity
FSA31_RS07980	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FSA31_RS07985	COG1518	maintenance of DNA repeat elements
FSA31_RS08035	COG0525	valine-tRNA ligase activity
FSA31_RS08070	COG1780	Probably involved in ribonucleotide reductase function
FSA31_RS08075	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FSA31_RS08080	COG2137	regulation of response to DNA damage stimulus
FSA31_RS08085	COG3557	Belongs to the UPF0374 family
FSA31_RS08135	COG0442	prolyl-tRNA aminoacylation
FSA31_RS08145	COG4589	Belongs to the CDS family
FSA31_RS08150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSA31_RS08155	COG1862	Preprotein translocase
FSA31_RS08165	COG0217	transcriptional regulatory protein
FSA31_RS08170	COG0789	Transcriptional regulator
FSA31_RS08195	COG1323	Belongs to the UPF0348 family
FSA31_RS08210	COG2226	methyltransferase
FSA31_RS08215	COG0799	negative regulation of ribosome biogenesis
FSA31_RS08220	COG1713	HD superfamily hydrolase involved in NAD metabolism
FSA31_RS08225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FSA31_RS08235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FSA31_RS08260	COG1819	glycosyl
FSA31_RS08265	COG0697	spore germination
FSA31_RS08275	COG0154	amidase activity
FSA31_RS08280	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSA31_RS08285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSA31_RS08290	COG1335	isochorismatase
FSA31_RS08295	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FSA31_RS08300	COG0436	Aminotransferase
FSA31_RS08305	COG1268	BioY protein
FSA31_RS08315	COG0561	phosphatase activity
FSA31_RS08320	COG0252	asparaginase activity
FSA31_RS08330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSA31_RS08335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSA31_RS08340	COG0736	holo-[acyl-carrier-protein] synthase activity
FSA31_RS08345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSA31_RS08350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSA31_RS08355	COG0653	protein targeting
FSA31_RS08360	COG1482	cell wall glycoprotein biosynthetic process
FSA31_RS08365	COG1940	carbohydrate kinase activity
FSA31_RS08370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FSA31_RS08370	COG2190	(PTS) system
FSA31_RS08370	COG1263	PTS System
FSA31_RS08375	COG1621	beta-fructofuranosidase activity
FSA31_RS08380	COG1609	Transcriptional regulator
FSA31_RS08385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSA31_RS08395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSA31_RS08400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSA31_RS08405	COG2131	deaminase
FSA31_RS08410	COG0006	proline dipeptidase activity
FSA31_RS08415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSA31_RS08450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FSA31_RS08455	COG0629	single-stranded DNA binding
FSA31_RS08460	COG0360	Binds together with S18 to 16S ribosomal RNA
FSA31_RS08475	COG1194	a g-specific adenine glycosylase
FSA31_RS08480	COG1063	alcohol dehydrogenase
FSA31_RS08485	COG3118	belongs to the thioredoxin family
FSA31_RS08490	COG1193	negative regulation of DNA recombination
FSA31_RS08505	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSA31_RS08510	COG0681	Belongs to the peptidase S26 family
FSA31_RS08515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSA31_RS08530	COG3715	PTS system
FSA31_RS08535	COG3716	PTS system mannose fructose sorbose family IID component
FSA31_RS08540	COG2274	protein secretion by the type I secretion system
FSA31_RS08565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSA31_RS08600	COG2274	protein secretion by the type I secretion system
FSA31_RS08645	COG3290	protein histidine kinase activity
FSA31_RS08655	COG0586	Pfam SNARE associated Golgi protein
FSA31_RS08665	COG1160	GTP binding
FSA31_RS08670	COG1484	DNA-dependent DNA replication
FSA31_RS08680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FSA31_RS08685	COG0745	RESPONSE REGULATOR receiver
FSA31_RS08700	COG1136	(ABC) transporter
FSA31_RS08705	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSA31_RS08710	COG0501	Belongs to the peptidase M48B family
FSA31_RS08715	COG1704	LemA family
FSA31_RS08720	COG0357	Ribosomal RNA small subunit methyltransferase G
FSA31_RS08730	COG1122	ATPase activity
FSA31_RS08735	COG4720	Psort location CytoplasmicMembrane, score
FSA31_RS08745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSA31_RS08755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSA31_RS08760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FSA31_RS08765	COG1464	Belongs to the NlpA lipoprotein family
FSA31_RS08770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSA31_RS08775	COG0495	leucyl-tRNA aminoacylation
FSA31_RS08805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSA31_RS08810	COG0564	pseudouridine synthase activity
FSA31_RS08820	COG0459	protein refolding
FSA31_RS08825	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FSA31_RS08835	COG3716	PTS system mannose fructose sorbose family IID component
FSA31_RS08840	COG3715	PTS system
FSA31_RS08865	COG2197	response regulator
FSA31_RS08870	COG4585	Histidine kinase
FSA31_RS08890	COG1846	Transcriptional regulator
FSA31_RS08895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSA31_RS08900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSA31_RS08910	COG1363	Peptidase, m42
FSA31_RS08915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FSA31_RS08935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSA31_RS08940	COG0827	DNA restriction-modification system
FSA31_RS08970	COG1459	type II secretion system
FSA31_RS08975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSA31_RS08985	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSA31_RS08990	COG0085	RNA polymerase activity
FSA31_RS08995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSA31_RS09000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSA31_RS09005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSA31_RS09010	COG1121	(ABC) transporter
FSA31_RS09020	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FSA31_RS09060	COG0203	ribosomal protein L17
FSA31_RS09065	COG0202	RNA polymerase activity
FSA31_RS09070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FSA31_RS09075	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FSA31_RS09085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FSA31_RS09090	COG0563	adenylate kinase activity
FSA31_RS09095	COG0201	protein transport
FSA31_RS09100	COG0200	Binds to the 23S rRNA
FSA31_RS09105	COG1841	ribosomal large subunit assembly
FSA31_RS09110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSA31_RS09120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSA31_RS09125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSA31_RS09130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FSA31_RS09135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FSA31_RS09140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FSA31_RS09145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FSA31_RS09150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FSA31_RS09155	COG0255	Belongs to the universal ribosomal protein uL29 family
FSA31_RS09160	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FSA31_RS09165	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FSA31_RS09170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FSA31_RS09180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FSA31_RS09185	COG0089	rRNA binding
FSA31_RS09195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FSA31_RS09200	COG0051	transcription antitermination factor activity, RNA binding
FSA31_RS09210	COG1621	beta-fructofuranosidase activity
FSA31_RS09215	COG0542	response to heat
FSA31_RS09220	COG4463	regulation of RNA biosynthetic process
FSA31_RS09225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FSA31_RS09230	COG0052	Belongs to the universal ribosomal protein uS2 family
FSA31_RS09245	COG1619	proteins homologs of microcin C7 resistance protein MccF
FSA31_RS09250	COG3590	peptidase
FSA31_RS09260	COG0366	Alpha amylase catalytic
FSA31_RS09265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FSA31_RS09265	COG1263	PTS System
FSA31_RS09270	COG2188	Transcriptional regulator
FSA31_RS09295	COG5297	Belongs to the glycosyl hydrolase family 6
FSA31_RS09305	COG1490	D-aminoacyl-tRNA deacylase activity
FSA31_RS09320	COG2190	(PTS) system
FSA31_RS09320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FSA31_RS09320	COG1263	PTS System
FSA31_RS09335	COG1609	Transcriptional regulator
FSA31_RS09340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSA31_RS09345	COG2264	protein methyltransferase activity
FSA31_RS09365	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSA31_RS09380	COG2217	Heavy metal translocating P-type atpase
FSA31_RS09390	COG2855	membrane
FSA31_RS09395	COG0583	DNA-binding transcription factor activity
FSA31_RS09405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FSA31_RS09415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSA31_RS09425	COG0463	Glycosyl transferase, family 2
FSA31_RS09430	COG0428	transporter
FSA31_RS09435	COG3022	response to hydroperoxide
FSA31_RS09470	COG3906	Belongs to the UPF0473 family
FSA31_RS09475	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSA31_RS09480	COG4472	Bacterial protein of unknown function (DUF965)
FSA31_RS09505	COG1393	Belongs to the ArsC family
FSA31_RS09510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FSA31_RS09515	COG1058	Belongs to the CinA family
FSA31_RS09515	COG1546	Belongs to the CinA family
FSA31_RS09520	COG0519	Catalyzes the synthesis of GMP from XMP
FSA31_RS09525	COG0632	four-way junction helicase activity
FSA31_RS09530	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FSA31_RS09540	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FSA31_RS09545	COG4550	Control of competence regulator ComK, YlbF/YmcA
FSA31_RS09550	COG1438	arginine binding
FSA31_RS09570	COG0018	arginyl-trna synthetase
FSA31_RS09575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FSA31_RS09580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FSA31_RS09585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSA31_RS09590	COG0124	histidyl-tRNA synthetase
FSA31_RS09595	COG0531	amino acid
FSA31_RS09600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FSA31_RS09605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FSA31_RS09625	COG0640	Transcriptional regulator
FSA31_RS09680	COG0789	Transcriptional regulator
FSA31_RS09685	COG1028	Short-chain dehydrogenase reductase Sdr
FSA31_RS09710	COG2094	Belongs to the DNA glycosylase MPG family
FSA31_RS09735	COG1012	belongs to the aldehyde dehydrogenase family
FSA31_RS09740	COG0129	dihydroxy-acid dehydratase activity
FSA31_RS09745	COG2151	metal-sulfur cluster biosynthetic enzyme
FSA31_RS09770	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSA31_RS09785	COG0305	Participates in initiation and elongation during chromosome replication
FSA31_RS09790	COG0359	binds to the 23S rRNA
FSA31_RS09800	COG0445	tRNA wobble uridine modification
FSA31_RS09810	COG0482	sulfurtransferase activity
FSA31_RS09815	COG0741	lytic transglycosylase activity
FSA31_RS09825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FSA31_RS09830	COG1122	ATPase activity
FSA31_RS09835	COG1122	ATPase activity
FSA31_RS09840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSA31_RS09850	COG0612	Peptidase, M16
FSA31_RS09865	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FSA31_RS09870	COG0516	GMP reductase activity
FSA31_RS09870	COG0517	IMP dehydrogenase activity
FSA31_RS09875	COG0180	Tryptophanyl-tRNA synthetase
FSA31_RS09880	COG0488	(ABC) transporter
FSA31_RS09910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FSA31_RS09920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSA31_RS09925	COG1475	DNA binding