locus-tag	class	description
M9H69_RS00010	COG0592	DNA-directed DNA polymerase activity
M9H69_RS00020	COG0012	GTP binding
M9H69_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M9H69_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M9H69_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M9H69_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M9H69_RS00125	COG0582	viral genome integration into host DNA
M9H69_RS00265	COG3728	DNA packaging
M9H69_RS00265	COG5484	DNA packaging
M9H69_RS00395	COG5632	N-Acetylmuramoyl-L-alanine amidase
M9H69_RS00395	COG5263	repeat protein
M9H69_RS00400	COG0756	dUTP diphosphatase activity
M9H69_RS00410	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M9H69_RS00420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M9H69_RS00425	COG1832	CoA-binding protein
M9H69_RS00430	COG2855	membrane
M9H69_RS00435	COG0436	Aminotransferase
M9H69_RS00450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M9H69_RS00480	COG2274	protein secretion by the type I secretion system
M9H69_RS00485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M9H69_RS00495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M9H69_RS00505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
M9H69_RS00510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M9H69_RS00515	COG0138	bifunctional purine biosynthesis protein purh
M9H69_RS00535	COG0151	Belongs to the GarS family
M9H69_RS00540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M9H69_RS00560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M9H69_RS00565	COG3064	Membrane
M9H69_RS00565	COG3525	Glycosyl hydrolase, family 20, catalytic domain
M9H69_RS00565	COG3583	domain protein
M9H69_RS00580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M9H69_RS00590	COG3716	PTS system mannose fructose sorbose family IID component
M9H69_RS00600	COG2222	sugar isomerase
M9H69_RS00605	COG3684	Belongs to the aldolase LacD family
M9H69_RS00660	COG0745	RESPONSE REGULATOR receiver
M9H69_RS00665	COG2357	RelA SpoT domain protein
M9H69_RS00670	COG1937	Protein conserved in bacteria
M9H69_RS00675	COG0425	Belongs to the sulfur carrier protein TusA family
M9H69_RS00675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M9H69_RS00680	COG0446	pyridine nucleotide-disulphide oxidoreductase
M9H69_RS00685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M9H69_RS00685	COG0425	Belongs to the sulfur carrier protein TusA family
M9H69_RS00745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M9H69_RS00760	COG0745	RESPONSE REGULATOR receiver
M9H69_RS00765	COG5002	protein histidine kinase activity
M9H69_RS00825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M9H69_RS00835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M9H69_RS00850	COG2151	metal-sulfur cluster biosynthetic enzyme
M9H69_RS00855	COG0124	histidyl-tRNA synthetase
M9H69_RS00860	COG1476	TRANSCRIPTIONal
M9H69_RS00890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M9H69_RS00900	COG1609	Transcriptional regulator
M9H69_RS00905	COG5521	maltodextrose utilization protein MalA
M9H69_RS00910	COG3833	ABC-type maltose transport systems, permease component
M9H69_RS00915	COG1175	transmembrane transport
M9H69_RS00920	COG2182	Extracellular solute-binding protein
M9H69_RS00925	COG1640	4-alpha-glucanotransferase
M9H69_RS00930	COG0058	SHG alpha-glucan phosphorylase activity
M9H69_RS00940	COG2226	methyltransferase
M9H69_RS00950	COG4499	WXG100 protein secretion system (Wss), protein YukC
M9H69_RS00950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M9H69_RS00955	COG0697	spore germination
M9H69_RS00970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M9H69_RS00985	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
M9H69_RS00990	COG1518	maintenance of DNA repeat elements
M9H69_RS00995	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
M9H69_RS01000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M9H69_RS01010	COG1132	(ABC) transporter
M9H69_RS01015	COG1132	(ABC) transporter
M9H69_RS01020	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
M9H69_RS01025	COG0166	Belongs to the GPI family
M9H69_RS01135	COG0534	Mate efflux family protein
M9H69_RS01140	COG0546	phosphoglycolate phosphatase activity
M9H69_RS01175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M9H69_RS01180	COG1459	type II secretion system
M9H69_RS01185	COG4537	Required for transformation and DNA binding
M9H69_RS01230	COG0706	membrane insertase activity
M9H69_RS01235	COG1847	R3H domain protein
M9H69_RS01245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M9H69_RS01255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M9H69_RS01265	COG1012	belongs to the aldehyde dehydrogenase family
M9H69_RS01265	COG1454	alcohol dehydrogenase
M9H69_RS01275	COG1136	(ABC) transporter
M9H69_RS01280	COG0577	efflux transmembrane transporter activity
M9H69_RS01295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M9H69_RS01300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M9H69_RS01395	COG2176	DNA-directed DNA polymerase activity
M9H69_RS01405	COG2309	aminopeptidase activity
M9H69_RS01410	COG2261	transglycosylase associated protein
M9H69_RS01415	COG1187	pseudouridine synthase activity
M9H69_RS01420	COG3579	cysteine-type endopeptidase activity
M9H69_RS01425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M9H69_RS01430	COG3716	PTS system mannose fructose sorbose family IID component
M9H69_RS01435	COG3715	PTS system
M9H69_RS01445	COG0561	phosphatase activity
M9H69_RS01450	COG2252	PERMEase
M9H69_RS01460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M9H69_RS01465	COG0285	dihydrofolate synthase activity
M9H69_RS01475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M9H69_RS01475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M9H69_RS01490	COG1609	Transcriptional regulator
M9H69_RS01495	COG0252	asparaginase activity
M9H69_RS01500	COG0561	phosphatase activity
M9H69_RS01505	COG0589	response to stress
M9H69_RS01510	COG0436	Aminotransferase
M9H69_RS01515	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M9H69_RS01520	COG0531	amino acid
M9H69_RS01525	COG0084	hydrolase, TatD family'
M9H69_RS01545	COG1162	GTPase activity
M9H69_RS01555	COG1564	THIamine pyrophosphokinase
M9H69_RS01565	COG3481	metal-dependent phosphohydrolase, HD sub domain
M9H69_RS01570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M9H69_RS01580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M9H69_RS01590	COG1254	Belongs to the acylphosphatase family
M9H69_RS01595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M9H69_RS01610	COG0742	ribosomal rna small subunit methyltransferase
M9H69_RS01620	COG3480	Lon protease (S16) C-terminal proteolytic domain
M9H69_RS01630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M9H69_RS01645	COG1253	flavin adenine dinucleotide binding
M9H69_RS01655	COG4166	transmembrane transport
M9H69_RS01660	COG0601	transmembrane transport
M9H69_RS01665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M9H69_RS01670	COG0444	Belongs to the ABC transporter superfamily
M9H69_RS01675	COG4608	Belongs to the ABC transporter superfamily
M9H69_RS01680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M9H69_RS01685	COG0569	domain protein
M9H69_RS01695	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M9H69_RS01700	COG0671	phosphoesterase, PA-phosphatase related
M9H69_RS01720	COG0072	phenylalanine-tRNA ligase activity
M9H69_RS01720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M9H69_RS01725	COG4152	abc transporter atp-binding protein
M9H69_RS01730	COG1668	transmembrane transport
M9H69_RS01735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
M9H69_RS01750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M9H69_RS01760	COG0583	DNA-binding transcription factor activity
M9H69_RS01770	COG0281	malic enzyme
M9H69_RS01795	COG0366	Alpha amylase catalytic
M9H69_RS01800	COG0386	Belongs to the glutathione peroxidase family
M9H69_RS01850	COG4839	cell division protein FtsL
M9H69_RS01855	COG0768	penicillin binding
M9H69_RS01865	COG0366	Alpha amylase catalytic
M9H69_RS01890	COG0517	IMP dehydrogenase activity
M9H69_RS01910	COG1187	pseudouridine synthase activity
M9H69_RS01920	COG4607	ABC-type enterochelin transport system periplasmic component
M9H69_RS01925	COG4604	ABC transporter, ATP-binding protein
M9H69_RS01930	COG4605	iron ion homeostasis
M9H69_RS01935	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M9H69_RS01940	COG1363	Peptidase, m42
M9H69_RS01950	COG1283	sodium-dependent phosphate transmembrane transporter activity
M9H69_RS01955	COG0366	Alpha amylase catalytic
M9H69_RS01960	COG0126	phosphoglycerate kinase activity
M9H69_RS01970	COG0789	Transcriptional regulator
M9H69_RS01975	COG0174	glutamine synthetase
M9H69_RS02000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
M9H69_RS02010	COG0484	heat shock protein binding
M9H69_RS02025	COG0537	adenosine 5'-monophosphoramidase activity
M9H69_RS02030	COG1131	(ABC) transporter
M9H69_RS02055	COG0195	Participates in both transcription termination and antitermination
M9H69_RS02060	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M9H69_RS02110	COG0519	Catalyzes the synthesis of GMP from XMP
M9H69_RS02120	COG0525	valine-tRNA ligase activity
M9H69_RS02140	COG0504	CTP synthase activity
M9H69_RS02150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M9H69_RS02155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M9H69_RS02160	COG4221	oxidoreductase activity
M9H69_RS02195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M9H69_RS02325	COG2207	Transcriptional regulator
M9H69_RS02330	COG3345	alpha-galactosidase
M9H69_RS02335	COG1653	transport
M9H69_RS02340	COG1175	transmembrane transport
M9H69_RS02345	COG0395	ABC-type sugar transport system, permease component
M9H69_RS02350	COG0366	Alpha amylase catalytic
M9H69_RS02370	COG1174	glycine betaine transport
M9H69_RS02380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M9H69_RS02390	COG1122	ATPase activity
M9H69_RS02430	COG1309	transcriptional regulator
M9H69_RS02435	COG1230	cation diffusion facilitator family transporter
M9H69_RS02440	COG1609	Transcriptional regulator
M9H69_RS02445	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
M9H69_RS02450	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M9H69_RS02460	COG2233	PERMEase
M9H69_RS02475	COG0708	Exodeoxyribonuclease III
M9H69_RS02485	COG2323	membrane
M9H69_RS02490	COG1132	(ABC) transporter
M9H69_RS02495	COG1132	(ABC) transporter
M9H69_RS02500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M9H69_RS02505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M9H69_RS02510	COG0133	tryptophan synthase activity
M9H69_RS02515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M9H69_RS02520	COG0512	Glutamine amidotransferase of anthranilate synthase
M9H69_RS02535	COG0135	phosphoribosylanthranilate isomerase activity
M9H69_RS02550	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M9H69_RS02575	COG0628	permease
M9H69_RS02600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M9H69_RS02615	COG1051	belongs to the nudix hydrolase family
M9H69_RS02620	COG2264	protein methyltransferase activity
M9H69_RS02625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M9H69_RS02630	COG1164	Oligoendopeptidase f
M9H69_RS02640	COG1733	regulation of RNA biosynthetic process
M9H69_RS02645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M9H69_RS02660	COG0720	synthase
M9H69_RS02670	COG3118	belongs to the thioredoxin family
M9H69_RS02690	COG1346	cytolysis
M9H69_RS02705	COG1396	sequence-specific DNA binding
M9H69_RS02715	COG1131	(ABC) transporter
M9H69_RS02720	COG1725	Transcriptional regulator
M9H69_RS02735	COG1484	DNA-dependent DNA replication
M9H69_RS02740	COG0778	Nitroreductase
M9H69_RS02765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M9H69_RS02770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M9H69_RS02785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M9H69_RS02790	COG3458	cephalosporin-C deacetylase activity
M9H69_RS02810	COG1175	transmembrane transport
M9H69_RS02815	COG0395	ABC-type sugar transport system, permease component
M9H69_RS02820	COG2731	YhcH YjgK YiaL family protein
M9H69_RS02830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M9H69_RS02845	COG0768	penicillin binding
M9H69_RS02915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M9H69_RS02920	COG1051	belongs to the nudix hydrolase family
M9H69_RS02940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M9H69_RS02960	COG3599	regulation of cell shape
M9H69_RS02965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M9H69_RS02975	COG0588	phosphoglycerate mutase activity
M9H69_RS02980	COG0577	efflux transmembrane transporter activity
M9H69_RS02980	COG1136	(ABC) transporter
M9H69_RS03000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M9H69_RS03020	COG0204	Acyl-transferase
M9H69_RS03025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M9H69_RS03030	COG2384	SAM-dependent methyltransferase
M9H69_RS03035	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M9H69_RS03040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M9H69_RS03050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M9H69_RS03055	COG0463	Glycosyl transferase, family 2
M9H69_RS03075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M9H69_RS03090	COG0251	oxidation-reduction process
M9H69_RS03100	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M9H69_RS03110	COG0492	ferredoxin-NADP+ reductase activity
M9H69_RS03115	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M9H69_RS03135	COG1307	EDD domain protein, DegV family
M9H69_RS03145	COG0617	tRNA 3'-terminal CCA addition
M9H69_RS03150	COG0488	(ABC) transporter
M9H69_RS03155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M9H69_RS03165	COG0242	peptide deformylase activity
M9H69_RS03190	COG0436	Aminotransferase
M9H69_RS03195	COG0017	Asparaginyl-tRNA synthetase
M9H69_RS03205	COG0360	Binds together with S18 to 16S ribosomal RNA
M9H69_RS03210	COG0629	single-stranded DNA binding
M9H69_RS03215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
M9H69_RS03235	COG1073	alpha beta
M9H69_RS03250	COG2723	6-phospho-beta-galactosidase activity
M9H69_RS03265	COG3064	Membrane
M9H69_RS03265	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M9H69_RS03295	COG0438	transferase activity, transferring glycosyl groups
M9H69_RS03320	COG0751	glycine-tRNA ligase activity
M9H69_RS03330	COG0431	NADPH-dependent FMN reductase
M9H69_RS03330	COG1053	succinate dehydrogenase
M9H69_RS03330	COG3976	FMN-binding domain protein
M9H69_RS03360	COG1272	protein, Hemolysin III
M9H69_RS03375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M9H69_RS03380	COG1393	Belongs to the ArsC family
M9H69_RS03390	COG1126	abc transporter atp-binding protein
M9H69_RS03400	COG0492	ferredoxin-NADP+ reductase activity
M9H69_RS03420	COG0561	phosphatase activity
M9H69_RS03440	COG1349	DNA-binding transcription factor activity
M9H69_RS03445	COG1105	Belongs to the carbohydrate kinase PfkB family
M9H69_RS03460	COG1674	ftsk spoiiie
M9H69_RS03460	COG0697	spore germination
M9H69_RS03470	COG1104	cysteine desulfurase activity
M9H69_RS03495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M9H69_RS03505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M9H69_RS03510	COG0697	spore germination
M9H69_RS03525	COG1704	LemA family
M9H69_RS03535	COG0488	(ABC) transporter
M9H69_RS03550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M9H69_RS03565	COG0505	Belongs to the CarA family
M9H69_RS03575	COG1914	H( )-stimulated, divalent metal cation uptake system
M9H69_RS03585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M9H69_RS03590	COG0716	FMN binding
M9H69_RS03605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M9H69_RS03610	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M9H69_RS03620	COG0300	oxidoreductase activity
M9H69_RS03670	COG3250	beta-galactosidase activity
M9H69_RS03680	COG1242	4 iron, 4 sulfur cluster binding
M9H69_RS03685	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M9H69_RS03695	COG0025	NhaP-type Na H and K H
M9H69_RS03715	COG4106	trans-aconitate 2-methyltransferase activity
M9H69_RS03730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
M9H69_RS03755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M9H69_RS03765	COG0647	UMP catabolic process
M9H69_RS03775	COG1393	Belongs to the ArsC family
M9H69_RS03785	COG0483	inositol monophosphate 1-phosphatase activity
M9H69_RS03790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M9H69_RS03790	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
M9H69_RS03795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M9H69_RS03800	COG0573	inorganic phosphate transmembrane transporter activity
M9H69_RS03805	COG0581	inorganic phosphate transmembrane transporter activity
M9H69_RS03810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M9H69_RS03815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M9H69_RS03820	COG0704	Plays a role in the regulation of phosphate uptake
M9H69_RS03825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9H69_RS03830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M9H69_RS03835	COG3527	Alpha-acetolactate decarboxylase
M9H69_RS03850	COG3842	ATPase activity
M9H69_RS03885	COG1337	RAMP superfamily
M9H69_RS03890	COG1567	CRISPR-associated RAMP protein, Csm4 family
M9H69_RS03915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M9H69_RS03925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M9H69_RS03950	COG0287	Prephenate dehydrogenase
M9H69_RS03955	COG3679	Belongs to the UPF0342 family
M9H69_RS03970	COG0077	Prephenate dehydratase
M9H69_RS03980	COG3475	LICD family
M9H69_RS03985	COG1215	transferase activity, transferring glycosyl groups
M9H69_RS03990	COG3475	LICD family
M9H69_RS03995	COG3475	LICD family
M9H69_RS04030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M9H69_RS04030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M9H69_RS04035	COG1132	(ABC) transporter
M9H69_RS04045	COG0402	S-adenosylhomocysteine deaminase activity
M9H69_RS04050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
M9H69_RS04055	COG0222	ribosome binding
M9H69_RS04070	COG0270	DNA (cytosine-5-)-methyltransferase activity
M9H69_RS04165	COG1136	(ABC) transporter
M9H69_RS04220	COG1396	sequence-specific DNA binding
M9H69_RS04225	COG0542	response to heat
M9H69_RS04235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M9H69_RS04250	COG5434	Belongs to the glycosyl hydrolase 28 family
M9H69_RS04260	COG0704	Plays a role in the regulation of phosphate uptake
M9H69_RS04265	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M9H69_RS04270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M9H69_RS04290	COG1178	ABC-type Fe3 transport system permease component
M9H69_RS04295	COG1285	pathogenesis
M9H69_RS04310	COG1285	pathogenesis
M9H69_RS04325	COG3843	relaxase mobilization nuclease domain protein
M9H69_RS04330	COG1396	sequence-specific DNA binding
M9H69_RS04340	COG4974	Belongs to the 'phage' integrase family
M9H69_RS04350	COG5504	Zn-dependent protease
M9H69_RS04360	COG0604	alcohol dehydrogenase
M9H69_RS04370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M9H69_RS04375	COG0167	dihydroorotate dehydrogenase activity
M9H69_RS04385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M9H69_RS04390	COG4470	Protein conserved in bacteria
M9H69_RS04395	COG0820	rRNA (adenine-C2-)-methyltransferase activity
M9H69_RS04405	COG0488	(ABC) transporter
M9H69_RS04460	COG1328	CTP reductase activity
M9H69_RS04460	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M9H69_RS04470	COG4443	Transcriptional Coactivator p15 (PC4)
M9H69_RS04490	COG1268	BioY protein
M9H69_RS04495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M9H69_RS04500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M9H69_RS04505	COG1136	(ABC) transporter
M9H69_RS04510	COG0577	efflux transmembrane transporter activity
M9H69_RS04515	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M9H69_RS04515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M9H69_RS04540	COG2813	Specifically methylates the guanine in position
M9H69_RS04545	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
M9H69_RS04555	COG0295	cytidine deaminase activity
M9H69_RS04560	COG1744	ABC transporter substrate-binding protein PnrA-like
M9H69_RS04565	COG3845	ABC transporter
M9H69_RS04570	COG4603	Belongs to the binding-protein-dependent transport system permease family
M9H69_RS04575	COG1079	Belongs to the binding-protein-dependent transport system permease family
M9H69_RS04585	COG0187	DNA topoisomerase II activity
M9H69_RS04595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M9H69_RS04600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M9H69_RS04620	COG0539	negative regulation of cytoplasmic translation
M9H69_RS04625	COG1956	GAF domain-containing protein
M9H69_RS04630	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M9H69_RS04645	COG0719	Fe-S assembly protein
M9H69_RS04650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M9H69_RS04660	COG0719	Fe-S assembly protein
M9H69_RS04665	COG0531	amino acid
M9H69_RS04670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M9H69_RS04675	COG1307	EDD domain protein, DegV family
M9H69_RS04685	COG0039	L-malate dehydrogenase activity
M9H69_RS04690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M9H69_RS04695	COG3764	Sortase (surface protein transpeptidase)
M9H69_RS04740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M9H69_RS04765	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M9H69_RS04770	COG1438	arginine binding
M9H69_RS04775	COG0497	DNA recombination
M9H69_RS04780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M9H69_RS04795	COG0758	DNA mediated transformation
M9H69_RS04800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M9H69_RS04805	COG2832	Protein of unknown function (DUF454)
M9H69_RS04810	COG3142	Participates in the control of copper homeostasis
M9H69_RS04825	COG0473	3-isopropylmalate dehydrogenase activity
M9H69_RS04850	COG1401	restriction endodeoxyribonuclease activity
M9H69_RS04875	COG1196	nuclear chromosome segregation
M9H69_RS04880	COG0196	riboflavin kinase activity
M9H69_RS04885	COG3689	TIGRFAM TIGR03943 family protein
M9H69_RS04890	COG0701	Predicted permease
M9H69_RS04895	COG2183	response to ionizing radiation
M9H69_RS04920	COG1136	(ABC) transporter
M9H69_RS04925	COG0577	efflux transmembrane transporter activity
M9H69_RS04935	COG0561	phosphatase activity
M9H69_RS04940	COG0561	phosphatase activity
M9H69_RS04945	COG0552	protein localization to endoplasmic reticulum
M9H69_RS04950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M9H69_RS04955	COG1126	abc transporter atp-binding protein
M9H69_RS04960	COG0765	amino acid transport
M9H69_RS05000	COG1827	regulation of RNA biosynthetic process
M9H69_RS05010	COG4684	Psort location CytoplasmicMembrane, score
M9H69_RS05015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M9H69_RS05020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M9H69_RS05030	COG0210	DNA helicase
M9H69_RS05040	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
M9H69_RS05060	COG1104	cysteine desulfurase activity
M9H69_RS05065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M9H69_RS05075	COG2357	RelA SpoT domain protein
M9H69_RS05085	COG0564	pseudouridine synthase activity
M9H69_RS05090	COG0280	phosphate acetyltransferase
M9H69_RS05095	COG1194	a g-specific adenine glycosylase
M9H69_RS05100	COG0745	RESPONSE REGULATOR receiver
M9H69_RS05110	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M9H69_RS05120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M9H69_RS05125	COG0488	(ABC) transporter
M9H69_RS05145	COG1523	belongs to the glycosyl hydrolase 13 family
M9H69_RS05150	COG1012	belongs to the aldehyde dehydrogenase family
M9H69_RS05155	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
M9H69_RS05165	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M9H69_RS05175	COG0560	Phosphoserine phosphatase
M9H69_RS05200	COG3708	Transcriptional regulator
M9H69_RS05200	COG2207	Transcriptional regulator
M9H69_RS05235	COG1051	belongs to the nudix hydrolase family
M9H69_RS05240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
M9H69_RS05245	COG0534	Mate efflux family protein
M9H69_RS05250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M9H69_RS05255	COG0022	dehydrogenase e1 component
M9H69_RS05260	COG0508	dehydrogenase complex catalyzes the overall conversion of
M9H69_RS05265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M9H69_RS05270	COG0095	Lipoate-protein ligase
M9H69_RS05325	COG0038	chloride channel
M9H69_RS05335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M9H69_RS05365	COG0561	phosphatase activity
M9H69_RS05370	COG1131	(ABC) transporter
M9H69_RS05380	COG2205	protein histidine kinase activity
M9H69_RS05385	COG0745	RESPONSE REGULATOR receiver
M9H69_RS05395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M9H69_RS05415	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
M9H69_RS05420	COG1982	Orn Lys Arg decarboxylase major
M9H69_RS05455	COG3196	Protein conserved in bacteria
M9H69_RS05500	COG1597	lipid kinase activity
M9H69_RS05525	COG1131	(ABC) transporter
M9H69_RS05570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M9H69_RS05580	COG0741	lytic transglycosylase activity
M9H69_RS05605	COG2890	protein-(glutamine-N5) methyltransferase activity
M9H69_RS05620	COG1435	thymidine kinase activity
M9H69_RS05625	COG1942	4-Oxalocrotonate Tautomerase
M9H69_RS05630	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
M9H69_RS05640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M9H69_RS05650	COG4708	membrane
M9H69_RS05655	COG2246	polysaccharide biosynthetic process
M9H69_RS05680	COG3443	Belongs to the bacterial solute-binding protein 9 family
M9H69_RS05680	COG0803	Belongs to the bacterial solute-binding protein 9 family
M9H69_RS05695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M9H69_RS05705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M9H69_RS05710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M9H69_RS05715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M9H69_RS05725	COG3684	Belongs to the aldolase LacD family
M9H69_RS05750	COG3775	system Galactitol-specific IIC component
M9H69_RS05765	COG4750	Nucleotidyl transferase
M9H69_RS05780	COG1063	alcohol dehydrogenase
M9H69_RS05795	COG0584	glycerophosphoryl diester phosphodiesterase
M9H69_RS05800	COG2176	DNA-directed DNA polymerase activity
M9H69_RS05820	COG0494	nUDIX hydrolase
M9H69_RS05825	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
M9H69_RS05840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M9H69_RS05860	COG1126	abc transporter atp-binding protein
M9H69_RS05870	COG0457	Tetratricopeptide repeat
M9H69_RS05875	COG0628	permease
M9H69_RS05880	COG2706	6-phosphogluconolactonase activity
M9H69_RS05910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
M9H69_RS05915	COG0356	it plays a direct role in the translocation of protons across the membrane
M9H69_RS05930	COG0826	peptidase U32
M9H69_RS05935	COG2188	Transcriptional regulator
M9H69_RS05945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M9H69_RS05960	COG0628	permease
M9H69_RS05965	COG1686	Belongs to the peptidase S11 family
M9H69_RS05970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M9H69_RS05975	COG0785	Cytochrome C biogenesis protein
M9H69_RS05980	COG0024	Methionine aminopeptidase
M9H69_RS05985	COG4109	DRTGG domain
M9H69_RS05995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M9H69_RS06000	COG0469	pyruvate kinase activity
M9H69_RS06020	COG1438	arginine binding
M9H69_RS06045	COG0438	transferase activity, transferring glycosyl groups
M9H69_RS06050	COG0438	transferase activity, transferring glycosyl groups
M9H69_RS06055	COG2151	metal-sulfur cluster biosynthetic enzyme
M9H69_RS06060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M9H69_RS06065	COG0358	DNA primase activity
M9H69_RS06085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
M9H69_RS06090	COG0772	Belongs to the SEDS family
M9H69_RS06100	COG4122	O-methyltransferase activity
M9H69_RS06120	COG0500	methyltransferase
M9H69_RS06120	COG3615	Tellurite resistance protein tehB
M9H69_RS06130	COG0557	exoribonuclease II activity
M9H69_RS06140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M9H69_RS06145	COG2814	Major facilitator Superfamily
M9H69_RS06150	COG0237	dephospho-CoA kinase activity
M9H69_RS06155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
M9H69_RS06165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M9H69_RS06175	COG1293	RNA-binding protein homologous to eukaryotic snRNP
M9H69_RS06185	COG0813	purine-nucleoside phosphorylase activity
M9H69_RS06195	COG0038	chloride channel
M9H69_RS06200	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
M9H69_RS06225	COG1136	(ABC) transporter
M9H69_RS06240	COG5002	protein histidine kinase activity
M9H69_RS06245	COG0745	RESPONSE REGULATOR receiver
M9H69_RS06290	COG1028	Short-chain dehydrogenase reductase Sdr
M9H69_RS06310	COG5263	repeat protein
M9H69_RS06310	COG4193	domain, Protein
M9H69_RS06310	COG5263	repeat protein
M9H69_RS06310	COG4193	domain, Protein
M9H69_RS06315	COG0167	dihydroorotate dehydrogenase activity
M9H69_RS06320	COG0543	2 iron, 2 sulfur cluster binding
M9H69_RS06335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
M9H69_RS06345	COG2333	competence protein COMEC
M9H69_RS06345	COG0658	competence protein
M9H69_RS06350	COG1596	polysaccharide export
M9H69_RS06350	COG1555	photosystem II stabilization
M9H69_RS06355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M9H69_RS06360	COG0686	Belongs to the AlaDH PNT family
M9H69_RS06365	COG1702	phosphate starvation-inducible protein PhoH
M9H69_RS06375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M9H69_RS06375	COG0456	acetyltransferase
M9H69_RS06380	COG2996	Protein conserved in bacteria
M9H69_RS06390	COG0528	UMP kinase activity
M9H69_RS06430	COG0470	DNA polymerase III
M9H69_RS06440	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M9H69_RS06455	COG0564	pseudouridine synthase activity
M9H69_RS06460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
M9H69_RS06465	COG0583	DNA-binding transcription factor activity
M9H69_RS06500	COG0513	Belongs to the DEAD box helicase family
M9H69_RS06510	COG1078	dGTPase activity
M9H69_RS06535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M9H69_RS06540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M9H69_RS06545	COG0077	Prephenate dehydratase
M9H69_RS06545	COG1605	Chorismate mutase
M9H69_RS06565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M9H69_RS06570	COG1940	carbohydrate kinase activity
M9H69_RS06580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M9H69_RS06595	COG2972	Histidine kinase
M9H69_RS06600	COG4753	response regulator
M9H69_RS06600	COG2207	Transcriptional regulator
M9H69_RS06605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M9H69_RS06605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M9H69_RS06610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M9H69_RS06615	COG0785	Cytochrome C biogenesis protein
M9H69_RS06620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M9H69_RS06630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M9H69_RS06660	COG1113	amino acid transport
M9H69_RS06670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M9H69_RS06695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M9H69_RS06700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M9H69_RS06705	COG0626	cystathionine gamma-synthase activity
M9H69_RS06710	COG4166	transmembrane transport
M9H69_RS06715	COG2244	polysaccharide biosynthetic process
M9H69_RS06720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M9H69_RS06725	COG3237	CsbD-like
M9H69_RS06745	COG2827	Endonuclease containing a URI domain
M9H69_RS06750	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M9H69_RS06755	COG1098	S1 RNA binding domain
M9H69_RS06765	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M9H69_RS06770	COG1215	transferase activity, transferring glycosyl groups
M9H69_RS06780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M9H69_RS06800	COG0656	L-ascorbic acid biosynthetic process
M9H69_RS06805	COG0726	polysaccharide deacetylase
M9H69_RS06810	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
M9H69_RS06815	COG0187	DNA topoisomerase II activity
M9H69_RS06825	COG0693	protein deglycase activity
M9H69_RS06830	COG0772	Belongs to the SEDS family
M9H69_RS06835	COG1199	ATP-dependent helicase activity
M9H69_RS06835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M9H69_RS06840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M9H69_RS06850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
M9H69_RS06860	COG1126	abc transporter atp-binding protein
M9H69_RS06865	COG0765	amino acid transport
M9H69_RS06870	COG4703	Protein of unknown function (DUF1797)
M9H69_RS06875	COG0542	response to heat
M9H69_RS06895	COG0513	Belongs to the DEAD box helicase family
M9H69_RS06905	COG1263	PTS System
M9H69_RS06905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M9H69_RS06905	COG2190	(PTS) system
M9H69_RS06910	COG2177	Part of the ABC transporter FtsEX involved in
M9H69_RS06915	COG2884	Cell division ATP-binding protein ftsE
M9H69_RS06925	COG0517	IMP dehydrogenase activity
M9H69_RS06925	COG0617	tRNA 3'-terminal CCA addition
M9H69_RS06925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M9H69_RS06940	COG4750	Nucleotidyl transferase
M9H69_RS06975	COG0740	serine-type endopeptidase activity
M9H69_RS06980	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
M9H69_RS06985	COG2131	deaminase
M9H69_RS06995	COG1307	EDD domain protein, DegV family
M9H69_RS07000	COG2081	HI0933 family
M9H69_RS07010	COG0789	Transcriptional regulator
M9H69_RS07015	COG0733	neurotransmitter:sodium symporter activity
M9H69_RS07020	COG1482	cell wall glycoprotein biosynthetic process
M9H69_RS07025	COG2723	6-phospho-beta-galactosidase activity
M9H69_RS07045	COG0028	Belongs to the TPP enzyme family
M9H69_RS07050	COG2217	Heavy metal translocating P-type atpase
M9H69_RS07070	COG0352	thiamine-phosphate diphosphorylase activity
M9H69_RS07085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M9H69_RS07095	COG4172	Belongs to the ABC transporter superfamily
M9H69_RS07110	COG1304	FMN binding
M9H69_RS07125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M9H69_RS07145	COG1217	gtp-binding protein TYPA
M9H69_RS07150	COG1187	pseudouridine synthase activity
M9H69_RS07170	COG0583	DNA-binding transcription factor activity
M9H69_RS07175	COG0860	N-Acetylmuramoyl-L-alanine amidase
M9H69_RS07195	COG1404	Belongs to the peptidase S8 family
M9H69_RS07210	COG4555	ABC transporter
M9H69_RS07215	COG0191	fructose-bisphosphate aldolase activity
M9H69_RS07220	COG5002	protein histidine kinase activity
M9H69_RS07225	COG0745	RESPONSE REGULATOR receiver
M9H69_RS07230	COG0577	efflux transmembrane transporter activity
M9H69_RS07235	COG1136	(ABC) transporter
M9H69_RS07240	COG0577	efflux transmembrane transporter activity
M9H69_RS07255	COG1335	isochorismatase
M9H69_RS07260	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M9H69_RS07265	COG0513	Belongs to the DEAD box helicase family
M9H69_RS07270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M9H69_RS07285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M9H69_RS07290	COG3442	glutamine amidotransferase
M9H69_RS07295	COG0006	proline dipeptidase activity
M9H69_RS07300	COG4720	Psort location CytoplasmicMembrane, score
M9H69_RS07305	COG0351	phosphomethylpyrimidine kinase
M9H69_RS07325	COG2824	Alkylphosphonate utilization operon protein PhnA
M9H69_RS07335	COG1132	(ABC) transporter
M9H69_RS07345	COG0149	triose-phosphate isomerase activity
M9H69_RS07360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M9H69_RS07380	COG1192	Involved in chromosome partitioning
M9H69_RS07390	COG3843	relaxase mobilization nuclease domain protein
M9H69_RS07515	COG1363	Peptidase, m42
M9H69_RS07525	COG1114	Component of the transport system for branched-chain amino acids
M9H69_RS07540	COG1573	uracil-dna glycosylase
M9H69_RS07585	COG5549	protein import
M9H69_RS07585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M9H69_RS07600	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M9H69_RS07600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M9H69_RS07610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9H69_RS07615	COG0765	amino acid transport
M9H69_RS07620	COG0765	amino acid transport
M9H69_RS07635	COG1959	2 iron, 2 sulfur cluster binding
M9H69_RS07655	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M9H69_RS07675	COG0745	RESPONSE REGULATOR receiver
M9H69_RS07690	COG3590	peptidase
M9H69_RS07710	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M9H69_RS07735	COG3842	ATPase activity
M9H69_RS07745	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
M9H69_RS07750	COG0215	cysteine-tRNA ligase activity
M9H69_RS07760	COG1045	serine acetyltransferase
M9H69_RS07775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M9H69_RS07780	COG3620	sequence-specific DNA binding
M9H69_RS07785	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
M9H69_RS07815	COG1940	carbohydrate kinase activity
M9H69_RS07820	COG1263	PTS System
M9H69_RS07820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M9H69_RS07820	COG2190	(PTS) system
M9H69_RS07825	COG1621	beta-fructofuranosidase activity
M9H69_RS07830	COG1609	Transcriptional regulator
M9H69_RS07840	COG3425	synthase
M9H69_RS07855	COG2815	serine threonine protein kinase
M9H69_RS07855	COG0515	serine threonine protein kinase
M9H69_RS07860	COG0631	protein serine/threonine phosphatase activity
M9H69_RS07865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M9H69_RS07865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M9H69_RS07875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M9H69_RS07885	COG0194	GDP metabolic process
M9H69_RS07900	COG4115	mRNA cleavage
M9H69_RS07915	COG2226	methyltransferase
M9H69_RS07920	COG0799	negative regulation of ribosome biogenesis
M9H69_RS07925	COG1713	HD superfamily hydrolase involved in NAD metabolism
M9H69_RS07930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
M9H69_RS07935	COG1534	Rna-binding protein
M9H69_RS07940	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M9H69_RS07945	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M9H69_RS07955	COG0668	transmembrane transport
M9H69_RS07960	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
M9H69_RS07975	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
M9H69_RS08040	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
M9H69_RS08045	COG0439	Biotin carboxylase
M9H69_RS08060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M9H69_RS08065	COG1028	Short-chain dehydrogenase reductase Sdr
M9H69_RS08070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M9H69_RS08080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M9H69_RS08090	COG1846	Transcriptional regulator
M9H69_RS08095	COG1024	Enoyl-CoA hydratase
M9H69_RS08100	COG0527	aspartate kinase activity
M9H69_RS08125	COG1115	amino acid carrier protein
M9H69_RS08150	COG0681	Belongs to the peptidase S26 family
M9H69_RS08155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M9H69_RS08170	COG2197	response regulator
M9H69_RS08175	COG4585	Histidine kinase
M9H69_RS08210	COG0745	RESPONSE REGULATOR receiver
M9H69_RS08215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M9H69_RS08225	COG0116	Belongs to the methyltransferase superfamily
M9H69_RS08260	COG0366	Alpha amylase catalytic
M9H69_RS08265	COG4166	transmembrane transport
M9H69_RS08270	COG1091	dTDP-4-dehydrorhamnose reductase activity
M9H69_RS08275	COG1088	dTDP-glucose 4,6-dehydratase activity
M9H69_RS08285	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M9H69_RS08290	COG0562	UDP-galactopyranose mutase
M9H69_RS08295	COG3274	enterobacterial common antigen metabolic process
M9H69_RS08325	COG0438	transferase activity, transferring glycosyl groups
M9H69_RS08335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M9H69_RS08340	COG3475	LICD family
M9H69_RS08355	COG0489	protein tyrosine kinase activity
M9H69_RS08360	COG3944	biosynthesis protein
M9H69_RS08365	COG4464	protein tyrosine phosphatase activity
M9H69_RS08375	COG4166	transmembrane transport
M9H69_RS08380	COG4166	transmembrane transport
M9H69_RS08385	COG0366	Alpha amylase catalytic
M9H69_RS08415	COG1131	(ABC) transporter
M9H69_RS08430	COG1882	Formate acetyltransferase
M9H69_RS08435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M9H69_RS08450	COG0765	amino acid transport
M9H69_RS08455	COG1126	abc transporter atp-binding protein
M9H69_RS08470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M9H69_RS08480	COG0440	acetolactate synthase activity
M9H69_RS08485	COG0028	Belongs to the TPP enzyme family
M9H69_RS08505	COG2197	response regulator
M9H69_RS08510	COG4585	Histidine kinase
M9H69_RS08520	COG1131	(ABC) transporter
M9H69_RS08535	COG1461	Dihydroxyacetone kinase
M9H69_RS08545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
M9H69_RS08585	COG0217	transcriptional regulatory protein
M9H69_RS08590	COG0534	Mate efflux family protein
M9H69_RS08610	COG1316	TRANSCRIPTIONal
M9H69_RS08620	COG0802	atpase or kinase
M9H69_RS08645	COG1523	belongs to the glycosyl hydrolase 13 family
M9H69_RS08650	COG1126	abc transporter atp-binding protein
M9H69_RS08655	COG0765	amino acid transport
M9H69_RS08660	COG0765	amino acid transport
M9H69_RS08665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9H69_RS08685	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
M9H69_RS08690	COG2189	Belongs to the N(4) N(6)-methyltransferase family
M9H69_RS08695	COG3421	Type III restriction
M9H69_RS08700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M9H69_RS08710	COG2723	6-phospho-beta-galactosidase activity
M9H69_RS08720	COG0750	zinc metalloprotease
M9H69_RS08725	COG4589	Belongs to the CDS family
M9H69_RS08730	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M9H69_RS08760	COG4977	sequence-specific DNA binding
M9H69_RS08760	COG1917	Cupin 2, conserved barrel domain protein
M9H69_RS08780	COG3279	Response regulator of the LytR AlgR family
M9H69_RS08810	COG0588	phosphoglycerate mutase activity
M9H69_RS08815	COG2848	UPF0210 protein
M9H69_RS08820	COG3830	Belongs to the UPF0237 family
M9H69_RS08830	COG0202	RNA polymerase activity
M9H69_RS08835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
M9H69_RS08845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M9H69_RS08850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
M9H69_RS08860	COG0201	protein transport
M9H69_RS08875	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
M9H69_RS08895	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
M9H69_RS08915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
M9H69_RS08940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
M9H69_RS08955	COG0088	Forms part of the polypeptide exit tunnel
M9H69_RS08975	COG0602	queuosine metabolic process
M9H69_RS08990	COG1328	CTP reductase activity
M9H69_RS09005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M9H69_RS09010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M9H69_RS09020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M9H69_RS09025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M9H69_RS09035	COG1454	alcohol dehydrogenase
M9H69_RS09045	COG0285	dihydrofolate synthase activity
M9H69_RS09070	COG1393	Belongs to the ArsC family
M9H69_RS09075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M9H69_RS09080	COG0006	proline dipeptidase activity
M9H69_RS09085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M9H69_RS09105	COG1619	proteins homologs of microcin C7 resistance protein MccF
M9H69_RS09115	COG2818	Glycosylase
M9H69_RS09135	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M9H69_RS09135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M9H69_RS09165	COG1438	arginine binding
M9H69_RS09185	COG1780	Probably involved in ribonucleotide reductase function
M9H69_RS09205	COG1192	Involved in chromosome partitioning
M9H69_RS09215	COG3843	relaxase mobilization nuclease domain protein
M9H69_RS09325	COG4753	response regulator
M9H69_RS09325	COG2207	Transcriptional regulator
M9H69_RS09330	COG2972	Histidine kinase
M9H69_RS09350	COG1696	Membrane protein involved in D-alanine export
M9H69_RS09360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M9H69_RS09365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M9H69_RS09370	COG1464	Belongs to the NlpA lipoprotein family
M9H69_RS09375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9H69_RS09400	COG1396	sequence-specific DNA binding
M9H69_RS09415	COG1214	PFAM Peptidase M22, glycoprotease
M9H69_RS09440	COG0494	nUDIX hydrolase
M9H69_RS09455	COG0137	argininosuccinate synthase activity
M9H69_RS09460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9H69_RS09465	COG1388	LysM domain
M9H69_RS09465	COG3584	3D domain protein
M9H69_RS09470	COG1760	l-serine dehydratase
M9H69_RS09475	COG1760	l-serine dehydratase
M9H69_RS09480	COG0546	phosphoglycolate phosphatase activity
M9H69_RS09490	COG1216	Glycosyl transferase, family 2
M9H69_RS09495	COG2807	transmembrane transport
M9H69_RS09550	COG1653	transport
M9H69_RS09555	COG0395	ABC-type sugar transport system, permease component
M9H69_RS09560	COG4209	transmembrane transport
M9H69_RS09590	COG0383	alpha-mannosidase activity
M9H69_RS09610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M9H69_RS09620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M9H69_RS09625	COG3537	Alpha-1,2-mannosidase
M9H69_RS09635	COG3443	Belongs to the bacterial solute-binding protein 9 family
M9H69_RS09635	COG0803	Belongs to the bacterial solute-binding protein 9 family
M9H69_RS09640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M9H69_RS09645	COG1121	(ABC) transporter
M9H69_RS09650	COG1846	Transcriptional regulator
M9H69_RS09655	COG0737	Belongs to the 5'-nucleotidase family
M9H69_RS09660	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M9H69_RS09670	COG1696	Membrane protein involved in D-alanine export
M9H69_RS09690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M9H69_RS09710	COG3201	nicotinamide mononucleotide transporter
M9H69_RS09715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
M9H69_RS09720	COG0542	response to heat
M9H69_RS09725	COG4463	regulation of RNA biosynthetic process
M9H69_RS09750	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M9H69_RS09755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M9H69_RS09760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9H69_RS09770	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M9H69_RS09770	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M9H69_RS09775	COG3942	CHAP domain
M9H69_RS09785	COG0305	Participates in initiation and elongation during chromosome replication
M9H69_RS09795	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
M9H69_RS09800	COG2070	2-Nitropropane dioxygenase
M9H69_RS09810	COG1960	acyl-CoA dehydrogenase activity
M9H69_RS09815	COG0583	DNA-binding transcription factor activity
M9H69_RS09820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M9H69_RS09825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M9H69_RS09830	COG1024	Enoyl-CoA hydratase
M9H69_RS09840	COG1250	3-hydroxyacyl-CoA dehydrogenase
M9H69_RS09845	COG1960	acyl-CoA dehydrogenase activity
M9H69_RS09855	COG1040	competence protein
M9H69_RS09860	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M9H69_RS09865	COG1739	Uncharacterized protein family UPF0029
M9H69_RS09905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
M9H69_RS09970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
M9H69_RS10020	COG0542	response to heat
M9H69_RS10025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M9H69_RS10025	COG0551	DNA topoisomerase type I activity
M9H69_RS10100	COG1484	DNA-dependent DNA replication
M9H69_RS10130	COG1191	sigma factor activity
M9H69_RS10135	COG2226	methyltransferase
M9H69_RS10210	COG3942	CHAP domain
M9H69_RS10220	COG1792	Involved in formation and maintenance of cell shape
M9H69_RS10225	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M9H69_RS10230	COG1122	ATPase activity
M9H69_RS10235	COG1122	ATPase activity
M9H69_RS10240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M9H69_RS10250	COG0612	Peptidase, M16
M9H69_RS10255	COG0612	Peptidase, M16
M9H69_RS10260	COG2501	S4 domain
M9H69_RS10270	COG0516	GMP reductase activity
M9H69_RS10270	COG0517	IMP dehydrogenase activity
M9H69_RS10275	COG0180	Tryptophanyl-tRNA synthetase
M9H69_RS10280	COG0488	(ABC) transporter
M9H69_RS10290	COG1511	domain protein
M9H69_RS10290	COG1511	domain protein
M9H69_RS10335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M9H69_RS10340	COG1475	DNA binding