locus-tag	class	description
JDY60_RS00060	COG5263	repeat protein
JDY60_RS00060	COG5632	N-Acetylmuramoyl-L-alanine amidase
JDY60_RS00105	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JDY60_RS00115	COG1461	Dihydroxyacetone kinase
JDY60_RS00135	COG1131	(ABC) transporter
JDY60_RS00145	COG4585	Histidine kinase
JDY60_RS00150	COG2197	response regulator
JDY60_RS00170	COG0028	Belongs to the TPP enzyme family
JDY60_RS00175	COG0440	acetolactate synthase activity
JDY60_RS00185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JDY60_RS00200	COG1126	abc transporter atp-binding protein
JDY60_RS00205	COG0765	amino acid transport
JDY60_RS00230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JDY60_RS00235	COG1882	Formate acetyltransferase
JDY60_RS00260	COG0366	Alpha amylase catalytic
JDY60_RS00265	COG0366	Alpha amylase catalytic
JDY60_RS00270	COG0386	Belongs to the glutathione peroxidase family
JDY60_RS00295	COG4839	cell division protein FtsL
JDY60_RS00300	COG0768	penicillin binding
JDY60_RS00310	COG0366	Alpha amylase catalytic
JDY60_RS00325	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JDY60_RS00335	COG0517	IMP dehydrogenase activity
JDY60_RS00355	COG1187	pseudouridine synthase activity
JDY60_RS00365	COG4607	ABC-type enterochelin transport system periplasmic component
JDY60_RS00370	COG4604	ABC transporter, ATP-binding protein
JDY60_RS00375	COG4605	iron ion homeostasis
JDY60_RS00380	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JDY60_RS00385	COG1363	Peptidase, m42
JDY60_RS00405	COG0126	phosphoglycerate kinase activity
JDY60_RS00420	COG0789	Transcriptional regulator
JDY60_RS00425	COG0174	glutamine synthetase
JDY60_RS00470	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JDY60_RS00480	COG0484	heat shock protein binding
JDY60_RS00490	COG0537	adenosine 5'-monophosphoramidase activity
JDY60_RS00495	COG1131	(ABC) transporter
JDY60_RS00520	COG0195	Participates in both transcription termination and antitermination
JDY60_RS00525	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JDY60_RS00575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JDY60_RS00585	COG0525	valine-tRNA ligase activity
JDY60_RS00600	COG0504	CTP synthase activity
JDY60_RS00610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JDY60_RS00615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JDY60_RS00620	COG4221	oxidoreductase activity
JDY60_RS00655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JDY60_RS00775	COG2207	Transcriptional regulator
JDY60_RS00780	COG3345	alpha-galactosidase
JDY60_RS00785	COG1653	transport
JDY60_RS00790	COG1175	transmembrane transport
JDY60_RS00795	COG0395	ABC-type sugar transport system, permease component
JDY60_RS00800	COG0366	Alpha amylase catalytic
JDY60_RS00825	COG1174	glycine betaine transport
JDY60_RS00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JDY60_RS00845	COG1122	ATPase activity
JDY60_RS00885	COG1309	transcriptional regulator
JDY60_RS00890	COG1230	cation diffusion facilitator family transporter
JDY60_RS00895	COG1609	Transcriptional regulator
JDY60_RS00900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JDY60_RS00905	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JDY60_RS00915	COG2233	PERMEase
JDY60_RS00930	COG0708	Exodeoxyribonuclease III
JDY60_RS00945	COG1132	(ABC) transporter
JDY60_RS00950	COG1132	(ABC) transporter
JDY60_RS00955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JDY60_RS00960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JDY60_RS00965	COG0133	tryptophan synthase activity
JDY60_RS00970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JDY60_RS00975	COG0512	Glutamine amidotransferase of anthranilate synthase
JDY60_RS00990	COG0135	phosphoribosylanthranilate isomerase activity
JDY60_RS01015	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JDY60_RS01035	COG3237	CsbD-like
JDY60_RS01055	COG2261	transglycosylase associated protein
JDY60_RS01075	COG0628	permease
JDY60_RS01095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JDY60_RS01105	COG1051	belongs to the nudix hydrolase family
JDY60_RS01115	COG2264	protein methyltransferase activity
JDY60_RS01120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JDY60_RS01125	COG1164	Oligoendopeptidase f
JDY60_RS01165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JDY60_RS01180	COG0720	synthase
JDY60_RS01190	COG3118	belongs to the thioredoxin family
JDY60_RS01210	COG1346	cytolysis
JDY60_RS01220	COG1395	domain, Protein
JDY60_RS01235	COG1131	(ABC) transporter
JDY60_RS01240	COG1725	Transcriptional regulator
JDY60_RS01255	COG1484	DNA-dependent DNA replication
JDY60_RS01295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JDY60_RS01300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JDY60_RS01315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JDY60_RS01320	COG3458	cephalosporin-C deacetylase activity
JDY60_RS01340	COG1175	transmembrane transport
JDY60_RS01345	COG0395	ABC-type sugar transport system, permease component
JDY60_RS01350	COG2731	YhcH YjgK YiaL family protein
JDY60_RS01360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JDY60_RS01370	COG2226	methyltransferase
JDY60_RS01380	COG0768	penicillin binding
JDY60_RS01395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JDY60_RS01400	COG1051	belongs to the nudix hydrolase family
JDY60_RS01420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JDY60_RS01440	COG3599	regulation of cell shape
JDY60_RS01445	COG3599	regulation of cell shape
JDY60_RS01450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JDY60_RS01455	COG3583	domain protein
JDY60_RS01455	COG3583	domain protein
JDY60_RS01460	COG3583	domain protein
JDY60_RS01470	COG3583	domain protein
JDY60_RS01470	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JDY60_RS01495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JDY60_RS01515	COG0204	Acyl-transferase
JDY60_RS01520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JDY60_RS01525	COG2384	SAM-dependent methyltransferase
JDY60_RS01530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JDY60_RS01535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JDY60_RS01540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JDY60_RS01545	COG0463	Glycosyl transferase, family 2
JDY60_RS01565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JDY60_RS01585	COG0251	oxidation-reduction process
JDY60_RS01595	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JDY60_RS01605	COG0492	ferredoxin-NADP+ reductase activity
JDY60_RS01610	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JDY60_RS01630	COG1307	EDD domain protein, DegV family
JDY60_RS01640	COG0617	tRNA 3'-terminal CCA addition
JDY60_RS01645	COG0488	(ABC) transporter
JDY60_RS01655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JDY60_RS01665	COG0242	peptide deformylase activity
JDY60_RS01680	COG3022	response to hydroperoxide
JDY60_RS01690	COG1846	Transcriptional regulator
JDY60_RS01700	COG0436	Aminotransferase
JDY60_RS01705	COG0017	Asparaginyl-tRNA synthetase
JDY60_RS01710	COG0360	Binds together with S18 to 16S ribosomal RNA
JDY60_RS01715	COG0629	single-stranded DNA binding
JDY60_RS01720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JDY60_RS01730	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JDY60_RS01740	COG1215	transferase activity, transferring glycosyl groups
JDY60_RS01745	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JDY60_RS01755	COG1098	S1 RNA binding domain
JDY60_RS01760	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JDY60_RS01765	COG2827	Endonuclease containing a URI domain
JDY60_RS01795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JDY60_RS01800	COG2244	polysaccharide biosynthetic process
JDY60_RS01805	COG4166	transmembrane transport
JDY60_RS01810	COG0626	cystathionine gamma-synthase activity
JDY60_RS01815	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JDY60_RS01820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JDY60_RS01845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JDY60_RS01855	COG1113	amino acid transport
JDY60_RS01875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JDY60_RS01885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JDY60_RS01890	COG0785	Cytochrome C biogenesis protein
JDY60_RS01895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JDY60_RS01900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JDY60_RS01900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JDY60_RS01905	COG4753	response regulator
JDY60_RS01905	COG2207	Transcriptional regulator
JDY60_RS01910	COG2972	Histidine kinase
JDY60_RS01925	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JDY60_RS01935	COG1940	carbohydrate kinase activity
JDY60_RS01955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JDY60_RS01970	COG0300	oxidoreductase activity
JDY60_RS01975	COG3250	beta-galactosidase activity
JDY60_RS01990	COG2226	methyltransferase
JDY60_RS02000	COG1242	4 iron, 4 sulfur cluster binding
JDY60_RS02005	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JDY60_RS02015	COG0025	NhaP-type Na H and K H
JDY60_RS02040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JDY60_RS02070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JDY60_RS02080	COG0647	UMP catabolic process
JDY60_RS02090	COG1393	Belongs to the ArsC family
JDY60_RS02100	COG0483	inositol monophosphate 1-phosphatase activity
JDY60_RS02105	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JDY60_RS02105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JDY60_RS02110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JDY60_RS02115	COG0573	inorganic phosphate transmembrane transporter activity
JDY60_RS02120	COG0581	inorganic phosphate transmembrane transporter activity
JDY60_RS02125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JDY60_RS02130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JDY60_RS02135	COG0704	Plays a role in the regulation of phosphate uptake
JDY60_RS02140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JDY60_RS02145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JDY60_RS02150	COG3527	Alpha-acetolactate decarboxylase
JDY60_RS02165	COG3842	ATPase activity
JDY60_RS02190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JDY60_RS02200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JDY60_RS02225	COG0287	Prephenate dehydrogenase
JDY60_RS02230	COG3679	Belongs to the UPF0342 family
JDY60_RS02245	COG0077	Prephenate dehydratase
JDY60_RS02295	COG3475	LICD family
JDY60_RS02300	COG1216	Glycosyl transferase, family 2
JDY60_RS02300	COG1442	glycosyl transferase family 8
JDY60_RS02305	COG3475	LICD family
JDY60_RS02340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JDY60_RS02340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JDY60_RS02345	COG1132	(ABC) transporter
JDY60_RS02355	COG0402	S-adenosylhomocysteine deaminase activity
JDY60_RS02360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JDY60_RS02365	COG0222	ribosome binding
JDY60_RS02370	COG5504	Zn-dependent protease
JDY60_RS02385	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JDY60_RS02390	COG0167	dihydroorotate dehydrogenase activity
JDY60_RS02400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JDY60_RS02405	COG4470	Protein conserved in bacteria
JDY60_RS02410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JDY60_RS02420	COG0488	(ABC) transporter
JDY60_RS02430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JDY60_RS02465	COG1328	CTP reductase activity
JDY60_RS02465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JDY60_RS02475	COG4443	Transcriptional Coactivator p15 (PC4)
JDY60_RS02485	COG1268	BioY protein
JDY60_RS02490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JDY60_RS02495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JDY60_RS02500	COG1136	(ABC) transporter
JDY60_RS02505	COG0577	efflux transmembrane transporter activity
JDY60_RS02510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JDY60_RS02510	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JDY60_RS02515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JDY60_RS02535	COG2813	Specifically methylates the guanine in position
JDY60_RS02540	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JDY60_RS02550	COG0295	cytidine deaminase activity
JDY60_RS02555	COG1744	ABC transporter substrate-binding protein PnrA-like
JDY60_RS02560	COG3845	ABC transporter
JDY60_RS02565	COG4603	Belongs to the binding-protein-dependent transport system permease family
JDY60_RS02570	COG1079	Belongs to the binding-protein-dependent transport system permease family
JDY60_RS02580	COG0187	DNA topoisomerase II activity
JDY60_RS02595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JDY60_RS02600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JDY60_RS02620	COG0539	negative regulation of cytoplasmic translation
JDY60_RS02625	COG1956	GAF domain-containing protein
JDY60_RS02630	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JDY60_RS02645	COG0719	Fe-S assembly protein
JDY60_RS02650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JDY60_RS02660	COG0719	Fe-S assembly protein
JDY60_RS02670	COG0531	amino acid
JDY60_RS02675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JDY60_RS02680	COG1307	EDD domain protein, DegV family
JDY60_RS02690	COG0039	L-malate dehydrogenase activity
JDY60_RS02695	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JDY60_RS02700	COG3764	Sortase (surface protein transpeptidase)
JDY60_RS02720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JDY60_RS02745	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JDY60_RS02750	COG1438	arginine binding
JDY60_RS02755	COG0497	DNA recombination
JDY60_RS02760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JDY60_RS02775	COG0758	DNA mediated transformation
JDY60_RS02780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JDY60_RS02785	COG2832	Protein of unknown function (DUF454)
JDY60_RS02790	COG3142	Participates in the control of copper homeostasis
JDY60_RS02805	COG0473	3-isopropylmalate dehydrogenase activity
JDY60_RS02820	COG0066	3-isopropylmalate dehydratase activity
JDY60_RS02830	COG1401	restriction endodeoxyribonuclease activity
JDY60_RS02850	COG0571	ribonuclease III activity
JDY60_RS02855	COG1196	nuclear chromosome segregation
JDY60_RS02860	COG0196	riboflavin kinase activity
JDY60_RS02865	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JDY60_RS02895	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
JDY60_RS02900	COG3541	Predicted nucleotidyltransferase
JDY60_RS02915	COG3689	TIGRFAM TIGR03943 family protein
JDY60_RS02920	COG0701	Predicted permease
JDY60_RS02925	COG2183	response to ionizing radiation
JDY60_RS02940	COG1136	(ABC) transporter
JDY60_RS02945	COG0577	efflux transmembrane transporter activity
JDY60_RS02955	COG0561	phosphatase activity
JDY60_RS02960	COG0561	phosphatase activity
JDY60_RS02965	COG0552	protein localization to endoplasmic reticulum
JDY60_RS02970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JDY60_RS02975	COG1126	abc transporter atp-binding protein
JDY60_RS02980	COG0765	amino acid transport
JDY60_RS03015	COG2816	NAD+ diphosphatase activity
JDY60_RS03020	COG1827	regulation of RNA biosynthetic process
JDY60_RS03035	COG4684	Psort location CytoplasmicMembrane, score
JDY60_RS03040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JDY60_RS03045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JDY60_RS03075	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JDY60_RS03095	COG1104	cysteine desulfurase activity
JDY60_RS03100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JDY60_RS03110	COG2357	RelA SpoT domain protein
JDY60_RS03120	COG0564	pseudouridine synthase activity
JDY60_RS03125	COG0280	phosphate acetyltransferase
JDY60_RS03130	COG1194	a g-specific adenine glycosylase
JDY60_RS03135	COG0745	RESPONSE REGULATOR receiver
JDY60_RS03145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JDY60_RS03150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JDY60_RS03170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JDY60_RS03180	COG0488	(ABC) transporter
JDY60_RS03190	COG2814	Major facilitator Superfamily
JDY60_RS03200	COG1523	belongs to the glycosyl hydrolase 13 family
JDY60_RS03205	COG1012	belongs to the aldehyde dehydrogenase family
JDY60_RS03210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JDY60_RS03220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JDY60_RS03230	COG0560	Phosphoserine phosphatase
JDY60_RS03255	COG3708	Transcriptional regulator
JDY60_RS03255	COG2207	Transcriptional regulator
JDY60_RS03290	COG1011	Hydrolase
JDY60_RS03305	COG1051	belongs to the nudix hydrolase family
JDY60_RS03310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JDY60_RS03315	COG0534	Mate efflux family protein
JDY60_RS03320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JDY60_RS03325	COG0022	dehydrogenase e1 component
JDY60_RS03330	COG0508	dehydrogenase complex catalyzes the overall conversion of
JDY60_RS03335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JDY60_RS03340	COG0095	Lipoate-protein ligase
JDY60_RS03405	COG0038	chloride channel
JDY60_RS03415	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JDY60_RS03445	COG1673	EVE domain
JDY60_RS03455	COG0561	phosphatase activity
JDY60_RS03460	COG1131	(ABC) transporter
JDY60_RS03470	COG2205	protein histidine kinase activity
JDY60_RS03475	COG0745	RESPONSE REGULATOR receiver
JDY60_RS03485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JDY60_RS03505	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JDY60_RS03510	COG1982	Orn Lys Arg decarboxylase major
JDY60_RS03535	COG0366	Alpha amylase catalytic
JDY60_RS03540	COG0135	phosphoribosylanthranilate isomerase activity
JDY60_RS03545	COG1597	lipid kinase activity
JDY60_RS03730	COG1674	ftsk spoiiie
JDY60_RS03735	COG4499	WXG100 protein secretion system (Wss), protein YukC
JDY60_RS03755	COG4842	Belongs to the WXG100 family
JDY60_RS03760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JDY60_RS03770	COG0741	lytic transglycosylase activity
JDY60_RS03795	COG2890	protein-(glutamine-N5) methyltransferase activity
JDY60_RS03805	COG1435	thymidine kinase activity
JDY60_RS03810	COG1942	4-Oxalocrotonate Tautomerase
JDY60_RS03815	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JDY60_RS03825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JDY60_RS03835	COG4708	membrane
JDY60_RS03840	COG2246	polysaccharide biosynthetic process
JDY60_RS03845	COG1970	mechanosensitive ion channel activity
JDY60_RS03860	COG4509	Sortase family
JDY60_RS03870	COG0681	Belongs to the peptidase S26 family
JDY60_RS03880	COG2195	Cleaves the N-terminal amino acid of tripeptides
JDY60_RS03890	COG3443	Belongs to the bacterial solute-binding protein 9 family
JDY60_RS03890	COG0803	Belongs to the bacterial solute-binding protein 9 family
JDY60_RS03905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JDY60_RS03910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JDY60_RS03915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JDY60_RS03920	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JDY60_RS03930	COG2723	6-phospho-beta-galactosidase activity
JDY60_RS03945	COG3711	transcriptional antiterminator
JDY60_RS03950	COG3684	Belongs to the aldolase LacD family
JDY60_RS03975	COG3775	system Galactitol-specific IIC component
JDY60_RS03990	COG4750	Nucleotidyl transferase
JDY60_RS04005	COG1063	alcohol dehydrogenase
JDY60_RS04020	COG0584	glycerophosphoryl diester phosphodiesterase
JDY60_RS04025	COG2176	DNA-directed DNA polymerase activity
JDY60_RS04045	COG0494	nUDIX hydrolase
JDY60_RS04050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JDY60_RS04065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JDY60_RS04085	COG1126	abc transporter atp-binding protein
JDY60_RS04105	COG0628	permease
JDY60_RS04110	COG2706	6-phosphogluconolactonase activity
JDY60_RS04160	COG0826	peptidase U32
JDY60_RS04165	COG2188	Transcriptional regulator
JDY60_RS04175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JDY60_RS04190	COG0628	permease
JDY60_RS04195	COG1686	Belongs to the peptidase S11 family
JDY60_RS04200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JDY60_RS04205	COG0785	Cytochrome C biogenesis protein
JDY60_RS04210	COG0024	Methionine aminopeptidase
JDY60_RS04215	COG4109	DRTGG domain
JDY60_RS04225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JDY60_RS04230	COG0469	pyruvate kinase activity
JDY60_RS04245	COG2936	dipeptidyl-peptidase activity
JDY60_RS04250	COG1438	arginine binding
JDY60_RS04275	COG0438	transferase activity, transferring glycosyl groups
JDY60_RS04280	COG0438	transferase activity, transferring glycosyl groups
JDY60_RS04285	COG2151	metal-sulfur cluster biosynthetic enzyme
JDY60_RS04290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JDY60_RS04295	COG0358	DNA primase activity
JDY60_RS04315	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JDY60_RS04320	COG0772	Belongs to the SEDS family
JDY60_RS04330	COG4122	O-methyltransferase activity
JDY60_RS04350	COG0500	methyltransferase
JDY60_RS04350	COG3615	Tellurite resistance protein tehB
JDY60_RS04360	COG0557	exoribonuclease II activity
JDY60_RS04370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JDY60_RS04375	COG2814	Major facilitator Superfamily
JDY60_RS04380	COG0237	dephospho-CoA kinase activity
JDY60_RS04385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JDY60_RS04395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JDY60_RS04405	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JDY60_RS04415	COG0813	purine-nucleoside phosphorylase activity
JDY60_RS04425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JDY60_RS04450	COG1136	(ABC) transporter
JDY60_RS04465	COG5002	protein histidine kinase activity
JDY60_RS04470	COG0745	RESPONSE REGULATOR receiver
JDY60_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
JDY60_RS04510	COG4989	oxidoreductase activity
JDY60_RS04520	COG4193	domain, Protein
JDY60_RS04520	COG5263	repeat protein
JDY60_RS04525	COG0167	dihydroorotate dehydrogenase activity
JDY60_RS04530	COG0543	2 iron, 2 sulfur cluster binding
JDY60_RS04545	COG0443	Heat shock 70 kDa protein
JDY60_RS04550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JDY60_RS04555	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JDY60_RS04565	COG0658	competence protein
JDY60_RS04565	COG2333	competence protein COMEC
JDY60_RS04570	COG1596	polysaccharide export
JDY60_RS04570	COG1555	photosystem II stabilization
JDY60_RS04580	COG0686	Belongs to the AlaDH PNT family
JDY60_RS04585	COG1702	phosphate starvation-inducible protein PhoH
JDY60_RS04595	COG0456	acetyltransferase
JDY60_RS04595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JDY60_RS04600	COG2996	Protein conserved in bacteria
JDY60_RS04610	COG0528	UMP kinase activity
JDY60_RS04635	COG0470	DNA polymerase III
JDY60_RS04645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JDY60_RS04660	COG0564	pseudouridine synthase activity
JDY60_RS04665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JDY60_RS04670	COG0583	DNA-binding transcription factor activity
JDY60_RS04700	COG0513	Belongs to the DEAD box helicase family
JDY60_RS04710	COG1078	dGTPase activity
JDY60_RS04780	COG1518	maintenance of DNA repeat elements
JDY60_RS04800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JDY60_RS04805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JDY60_RS04810	COG1605	Chorismate mutase
JDY60_RS04810	COG0077	Prephenate dehydratase
JDY60_RS04815	COG0716	FMN binding
JDY60_RS04820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JDY60_RS04845	COG0505	Belongs to the CarA family
JDY60_RS04860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JDY60_RS04875	COG0488	(ABC) transporter
JDY60_RS04880	COG1266	CAAX protease self-immunity
JDY60_RS04890	COG1704	LemA family
JDY60_RS04905	COG0697	spore germination
JDY60_RS04920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JDY60_RS04945	COG1104	cysteine desulfurase activity
JDY60_RS04955	COG1674	ftsk spoiiie
JDY60_RS04955	COG0697	spore germination
JDY60_RS04960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JDY60_RS04960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JDY60_RS04960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JDY60_RS04965	COG1105	Belongs to the carbohydrate kinase PfkB family
JDY60_RS04970	COG1349	DNA-binding transcription factor activity
JDY60_RS05000	COG0561	phosphatase activity
JDY60_RS05020	COG0492	ferredoxin-NADP+ reductase activity
JDY60_RS05030	COG1126	abc transporter atp-binding protein
JDY60_RS05040	COG1393	Belongs to the ArsC family
JDY60_RS05060	COG1272	protein, Hemolysin III
JDY60_RS05090	COG1053	succinate dehydrogenase
JDY60_RS05090	COG0431	NADPH-dependent FMN reductase
JDY60_RS05090	COG3976	FMN-binding domain protein
JDY60_RS05120	COG0656	L-ascorbic acid biosynthetic process
JDY60_RS05125	COG0726	polysaccharide deacetylase
JDY60_RS05135	COG0187	DNA topoisomerase II activity
JDY60_RS05145	COG0366	Alpha amylase catalytic
JDY60_RS05145	COG5263	repeat protein
JDY60_RS05150	COG1396	sequence-specific DNA binding
JDY60_RS05160	COG0772	Belongs to the SEDS family
JDY60_RS05165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JDY60_RS05165	COG1199	ATP-dependent helicase activity
JDY60_RS05170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JDY60_RS05175	COG3250	beta-galactosidase activity
JDY60_RS05185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JDY60_RS05195	COG1126	abc transporter atp-binding protein
JDY60_RS05200	COG0765	amino acid transport
JDY60_RS05205	COG4703	Protein of unknown function (DUF1797)
JDY60_RS05210	COG0542	response to heat
JDY60_RS05230	COG0513	Belongs to the DEAD box helicase family
JDY60_RS05240	COG1263	PTS System
JDY60_RS05240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JDY60_RS05240	COG2190	(PTS) system
JDY60_RS05245	COG2177	Part of the ABC transporter FtsEX involved in
JDY60_RS05250	COG2884	Cell division ATP-binding protein ftsE
JDY60_RS05260	COG0517	IMP dehydrogenase activity
JDY60_RS05260	COG0617	tRNA 3'-terminal CCA addition
JDY60_RS05260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JDY60_RS05295	COG0740	serine-type endopeptidase activity
JDY60_RS05300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JDY60_RS05305	COG2131	deaminase
JDY60_RS05315	COG1307	EDD domain protein, DegV family
JDY60_RS05320	COG2081	HI0933 family
JDY60_RS05335	COG0789	Transcriptional regulator
JDY60_RS05340	COG0733	neurotransmitter:sodium symporter activity
JDY60_RS05345	COG1482	cell wall glycoprotein biosynthetic process
JDY60_RS05350	COG2723	6-phospho-beta-galactosidase activity
JDY60_RS05370	COG0028	Belongs to the TPP enzyme family
JDY60_RS05375	COG2217	Heavy metal translocating P-type atpase
JDY60_RS05395	COG0352	thiamine-phosphate diphosphorylase activity
JDY60_RS05410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JDY60_RS05420	COG4172	Belongs to the ABC transporter superfamily
JDY60_RS05435	COG1304	FMN binding
JDY60_RS05445	COG0765	amino acid transport
JDY60_RS05450	COG1126	abc transporter atp-binding protein
JDY60_RS05455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JDY60_RS05470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JDY60_RS05490	COG1217	gtp-binding protein TYPA
JDY60_RS05495	COG1187	pseudouridine synthase activity
JDY60_RS05515	COG0583	DNA-binding transcription factor activity
JDY60_RS05520	COG0860	N-Acetylmuramoyl-L-alanine amidase
JDY60_RS05520	COG2247	cell wall binding repeat
JDY60_RS05535	COG1404	Belongs to the peptidase S8 family
JDY60_RS05550	COG4555	ABC transporter
JDY60_RS05555	COG2020	methyltransferase activity
JDY60_RS05560	COG0191	fructose-bisphosphate aldolase activity
JDY60_RS05565	COG5002	protein histidine kinase activity
JDY60_RS05570	COG0745	RESPONSE REGULATOR receiver
JDY60_RS05575	COG0577	efflux transmembrane transporter activity
JDY60_RS05580	COG1136	(ABC) transporter
JDY60_RS05585	COG0577	efflux transmembrane transporter activity
JDY60_RS05595	COG1335	isochorismatase
JDY60_RS05600	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JDY60_RS05605	COG0513	Belongs to the DEAD box helicase family
JDY60_RS05610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JDY60_RS05615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JDY60_RS05620	COG3442	glutamine amidotransferase
JDY60_RS05625	COG0006	proline dipeptidase activity
JDY60_RS05630	COG4720	Psort location CytoplasmicMembrane, score
JDY60_RS05635	COG0351	phosphomethylpyrimidine kinase
JDY60_RS05655	COG2824	Alkylphosphonate utilization operon protein PhnA
JDY60_RS05670	COG3935	DnaD domain protein
JDY60_RS05680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JDY60_RS05705	COG1363	Peptidase, m42
JDY60_RS05710	COG4808	Protein conserved in bacteria
JDY60_RS05720	COG1114	Component of the transport system for branched-chain amino acids
JDY60_RS05730	COG1573	uracil-dna glycosylase
JDY60_RS05770	COG3942	CHAP domain
JDY60_RS05775	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JDY60_RS05775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JDY60_RS05785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JDY60_RS05790	COG0765	amino acid transport
JDY60_RS05795	COG0765	amino acid transport
JDY60_RS05810	COG1959	2 iron, 2 sulfur cluster binding
JDY60_RS05835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JDY60_RS05855	COG0745	RESPONSE REGULATOR receiver
JDY60_RS05880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JDY60_RS05890	COG3590	peptidase
JDY60_RS05910	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JDY60_RS05935	COG3842	ATPase activity
JDY60_RS05945	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JDY60_RS05950	COG0215	cysteine-tRNA ligase activity
JDY60_RS05970	COG1045	serine acetyltransferase
JDY60_RS05985	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JDY60_RS05990	COG3620	sequence-specific DNA binding
JDY60_RS06035	COG2189	Belongs to the N(4) N(6)-methyltransferase family
JDY60_RS06040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JDY60_RS06070	COG1940	carbohydrate kinase activity
JDY60_RS06075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JDY60_RS06075	COG1263	PTS System
JDY60_RS06075	COG2190	(PTS) system
JDY60_RS06080	COG1621	beta-fructofuranosidase activity
JDY60_RS06085	COG1609	Transcriptional regulator
JDY60_RS06095	COG3425	synthase
JDY60_RS06110	COG2815	serine threonine protein kinase
JDY60_RS06110	COG0515	serine threonine protein kinase
JDY60_RS06115	COG0631	protein serine/threonine phosphatase activity
JDY60_RS06120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JDY60_RS06120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JDY60_RS06130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JDY60_RS06140	COG0194	GDP metabolic process
JDY60_RS06185	COG2226	methyltransferase
JDY60_RS06190	COG0799	negative regulation of ribosome biogenesis
JDY60_RS06195	COG1713	HD superfamily hydrolase involved in NAD metabolism
JDY60_RS06200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JDY60_RS06205	COG1534	Rna-binding protein
JDY60_RS06210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JDY60_RS06215	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JDY60_RS06225	COG0668	transmembrane transport
JDY60_RS06230	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JDY60_RS06260	COG0438	transferase activity, transferring glycosyl groups
JDY60_RS06265	COG0438	transferase activity, transferring glycosyl groups
JDY60_RS06270	COG0653	protein targeting
JDY60_RS06290	COG0201	protein transport
JDY60_RS06295	COG1442	glycosyl transferase family 8
JDY60_RS06300	COG1442	glycosyl transferase family 8
JDY60_RS06310	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JDY60_RS06375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JDY60_RS06380	COG0439	Biotin carboxylase
JDY60_RS06395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JDY60_RS06400	COG1028	Short-chain dehydrogenase reductase Sdr
JDY60_RS06405	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JDY60_RS06415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JDY60_RS06425	COG1846	Transcriptional regulator
JDY60_RS06430	COG1024	Enoyl-CoA hydratase
JDY60_RS06435	COG0527	aspartate kinase activity
JDY60_RS06465	COG1115	amino acid carrier protein
JDY60_RS06490	COG0681	Belongs to the peptidase S26 family
JDY60_RS06495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JDY60_RS06500	COG0544	peptidyl-prolyl cis-trans isomerase activity
JDY60_RS06510	COG2197	response regulator
JDY60_RS06515	COG4585	Histidine kinase
JDY60_RS06540	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JDY60_RS06555	COG0745	RESPONSE REGULATOR receiver
JDY60_RS06560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JDY60_RS06570	COG0116	Belongs to the methyltransferase superfamily
JDY60_RS06605	COG0366	Alpha amylase catalytic
JDY60_RS06605	COG0366	Alpha amylase catalytic
JDY60_RS06610	COG4166	transmembrane transport
JDY60_RS06615	COG1091	dTDP-4-dehydrorhamnose reductase activity
JDY60_RS06620	COG1088	dTDP-glucose 4,6-dehydratase activity
JDY60_RS06630	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JDY60_RS06635	COG0438	transferase activity, transferring glycosyl groups
JDY60_RS06640	COG0562	UDP-galactopyranose mutase
JDY60_RS06655	COG1442	glycosyl transferase family 8
JDY60_RS06655	COG1216	Glycosyl transferase, family 2
JDY60_RS06670	COG0297	glycogen (starch) synthase activity
JDY60_RS06685	COG0489	protein tyrosine kinase activity
JDY60_RS06690	COG3944	biosynthesis protein
JDY60_RS06695	COG4464	protein tyrosine phosphatase activity
JDY60_RS06705	COG4166	transmembrane transport
JDY60_RS06710	COG4166	transmembrane transport
JDY60_RS06735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JDY60_RS06740	COG1668	transmembrane transport
JDY60_RS06745	COG4152	abc transporter atp-binding protein
JDY60_RS06750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JDY60_RS06750	COG0072	phenylalanine-tRNA ligase activity
JDY60_RS06760	COG0671	phosphoesterase, PA-phosphatase related
JDY60_RS06765	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JDY60_RS06775	COG0569	domain protein
JDY60_RS06780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JDY60_RS06785	COG4608	Belongs to the ABC transporter superfamily
JDY60_RS06790	COG0444	Belongs to the ABC transporter superfamily
JDY60_RS06795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JDY60_RS06800	COG0601	transmembrane transport
JDY60_RS06805	COG4166	transmembrane transport
JDY60_RS06815	COG1253	flavin adenine dinucleotide binding
JDY60_RS06830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JDY60_RS06840	COG3480	Lon protease (S16) C-terminal proteolytic domain
JDY60_RS06850	COG0742	ribosomal rna small subunit methyltransferase
JDY60_RS06865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JDY60_RS06870	COG1254	Belongs to the acylphosphatase family
JDY60_RS06880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JDY60_RS06890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JDY60_RS06895	COG3481	metal-dependent phosphohydrolase, HD sub domain
JDY60_RS06905	COG1564	THIamine pyrophosphokinase
JDY60_RS06915	COG1162	GTPase activity
JDY60_RS06920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JDY60_RS06940	COG0084	hydrolase, TatD family'
JDY60_RS06945	COG0531	amino acid
JDY60_RS06955	COG0436	Aminotransferase
JDY60_RS06965	COG0589	response to stress
JDY60_RS06975	COG0561	phosphatase activity
JDY60_RS06980	COG0252	asparaginase activity
JDY60_RS06985	COG1609	Transcriptional regulator
JDY60_RS07000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JDY60_RS07000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JDY60_RS07010	COG0285	dihydrofolate synthase activity
JDY60_RS07015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JDY60_RS07025	COG2252	PERMEase
JDY60_RS07030	COG0561	phosphatase activity
JDY60_RS07040	COG3715	PTS system
JDY60_RS07045	COG3716	PTS system mannose fructose sorbose family IID component
JDY60_RS07050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JDY60_RS07055	COG3579	cysteine-type endopeptidase activity
JDY60_RS07060	COG1187	pseudouridine synthase activity
JDY60_RS07065	COG2261	transglycosylase associated protein
JDY60_RS07070	COG2309	aminopeptidase activity
JDY60_RS07100	COG2176	DNA-directed DNA polymerase activity
JDY60_RS07190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JDY60_RS07195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JDY60_RS07210	COG1012	belongs to the aldehyde dehydrogenase family
JDY60_RS07210	COG1454	alcohol dehydrogenase
JDY60_RS07220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JDY60_RS07225	COG1862	Preprotein translocase
JDY60_RS07230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JDY60_RS07240	COG1847	R3H domain protein
JDY60_RS07245	COG0706	membrane insertase activity
JDY60_RS07290	COG4537	Required for transformation and DNA binding
JDY60_RS07295	COG1459	type II secretion system
JDY60_RS07300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JDY60_RS07330	COG3759	membrane
JDY60_RS07350	COG0546	phosphoglycolate phosphatase activity
JDY60_RS07355	COG0534	Mate efflux family protein
JDY60_RS07465	COG0166	Belongs to the GPI family
JDY60_RS07470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JDY60_RS07475	COG1132	(ABC) transporter
JDY60_RS07480	COG1132	(ABC) transporter
JDY60_RS07490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JDY60_RS07500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JDY60_RS07515	COG0697	spore germination
JDY60_RS07520	COG4499	WXG100 protein secretion system (Wss), protein YukC
JDY60_RS07520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JDY60_RS07530	COG2217	Heavy metal translocating P-type atpase
JDY60_RS07540	COG2226	methyltransferase
JDY60_RS07545	COG0058	SHG alpha-glucan phosphorylase activity
JDY60_RS07550	COG1640	4-alpha-glucanotransferase
JDY60_RS07555	COG2182	Extracellular solute-binding protein
JDY60_RS07560	COG1175	transmembrane transport
JDY60_RS07565	COG3833	ABC-type maltose transport systems, permease component
JDY60_RS07570	COG5521	maltodextrose utilization protein MalA
JDY60_RS07575	COG1609	Transcriptional regulator
JDY60_RS07580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JDY60_RS07620	COG1476	TRANSCRIPTIONal
JDY60_RS07630	COG2151	metal-sulfur cluster biosynthetic enzyme
JDY60_RS07645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JDY60_RS07690	COG5002	protein histidine kinase activity
JDY60_RS07695	COG0745	RESPONSE REGULATOR receiver
JDY60_RS07710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JDY60_RS07720	COG1309	transcriptional regulator
JDY60_RS07740	COG0110	maltose O-acetyltransferase activity
JDY60_RS07745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JDY60_RS07745	COG0425	Belongs to the sulfur carrier protein TusA family
JDY60_RS07750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JDY60_RS07750	COG0425	Belongs to the sulfur carrier protein TusA family
JDY60_RS07755	COG1937	Protein conserved in bacteria
JDY60_RS07790	COG2514	catechol 2,3-dioxygenase activity
JDY60_RS07800	COG3684	Belongs to the aldolase LacD family
JDY60_RS07805	COG2222	sugar isomerase
JDY60_RS07815	COG3716	PTS system mannose fructose sorbose family IID component
JDY60_RS07820	COG3715	PTS system
JDY60_RS07825	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JDY60_RS07840	COG3064	Membrane
JDY60_RS07840	COG3583	domain protein
JDY60_RS07840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JDY60_RS07845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JDY60_RS07865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JDY60_RS07870	COG0151	Belongs to the GarS family
JDY60_RS07890	COG0138	bifunctional purine biosynthesis protein purh
JDY60_RS07900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JDY60_RS07905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JDY60_RS07915	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JDY60_RS07925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JDY60_RS07930	COG2274	protein secretion by the type I secretion system
JDY60_RS07965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JDY60_RS07980	COG0436	Aminotransferase
JDY60_RS07985	COG2855	membrane
JDY60_RS07990	COG1832	CoA-binding protein
JDY60_RS07995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JDY60_RS08005	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JDY60_RS08015	COG0756	dUTP diphosphatase activity
JDY60_RS08070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JDY60_RS08075	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JDY60_RS08095	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JDY60_RS08100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JDY60_RS08110	COG0012	GTP binding
JDY60_RS08120	COG0592	DNA-directed DNA polymerase activity
JDY60_RS08130	COG1475	DNA binding
JDY60_RS08135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JDY60_RS08180	COG1511	domain protein
JDY60_RS08180	COG1511	domain protein
JDY60_RS08190	COG0488	(ABC) transporter
JDY60_RS08195	COG0180	Tryptophanyl-tRNA synthetase
JDY60_RS08200	COG0517	IMP dehydrogenase activity
JDY60_RS08200	COG0516	GMP reductase activity
JDY60_RS08210	COG2501	S4 domain
JDY60_RS08215	COG0612	Peptidase, M16
JDY60_RS08220	COG0612	Peptidase, M16
JDY60_RS08230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JDY60_RS08235	COG1122	ATPase activity
JDY60_RS08240	COG1122	ATPase activity
JDY60_RS08245	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JDY60_RS08250	COG1792	Involved in formation and maintenance of cell shape
JDY60_RS08260	COG3942	CHAP domain
JDY60_RS08285	COG1739	Uncharacterized protein family UPF0029
JDY60_RS08290	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JDY60_RS08295	COG1040	competence protein
JDY60_RS08310	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JDY60_RS08320	COG0305	Participates in initiation and elongation during chromosome replication
JDY60_RS08330	COG3942	CHAP domain
JDY60_RS08340	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JDY60_RS08340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JDY60_RS08350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JDY60_RS08355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JDY60_RS08360	COG1116	anion transmembrane transporter activity
JDY60_RS08370	COG4463	regulation of RNA biosynthetic process
JDY60_RS08375	COG0542	response to heat
JDY60_RS08385	COG3201	nicotinamide mononucleotide transporter
JDY60_RS08405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JDY60_RS08425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JDY60_RS08430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JDY60_RS08445	COG1696	Membrane protein involved in D-alanine export
JDY60_RS08455	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JDY60_RS08460	COG0737	Belongs to the 5'-nucleotidase family
JDY60_RS08465	COG1846	Transcriptional regulator
JDY60_RS08470	COG1121	(ABC) transporter
JDY60_RS08475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JDY60_RS08480	COG0803	Belongs to the bacterial solute-binding protein 9 family
JDY60_RS08480	COG3443	Belongs to the bacterial solute-binding protein 9 family
JDY60_RS08490	COG3537	Alpha-1,2-mannosidase
JDY60_RS08505	COG0383	alpha-mannosidase activity
JDY60_RS08520	COG4209	transmembrane transport
JDY60_RS08525	COG0395	ABC-type sugar transport system, permease component
JDY60_RS08530	COG1653	transport
JDY60_RS08575	COG2807	transmembrane transport
JDY60_RS08580	COG1216	Glycosyl transferase, family 2
JDY60_RS08590	COG0546	phosphoglycolate phosphatase activity
JDY60_RS08595	COG1760	l-serine dehydratase
JDY60_RS08600	COG1760	l-serine dehydratase
JDY60_RS08605	COG1388	LysM domain
JDY60_RS08605	COG3584	3D domain protein
JDY60_RS08610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JDY60_RS08615	COG0137	argininosuccinate synthase activity
JDY60_RS08630	COG0494	nUDIX hydrolase
JDY60_RS08635	COG0494	nUDIX hydrolase
JDY60_RS08640	COG0445	tRNA wobble uridine modification
JDY60_RS08665	COG1214	PFAM Peptidase M22, glycoprotease
JDY60_RS08680	COG1396	sequence-specific DNA binding
JDY60_RS08710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JDY60_RS08715	COG1464	Belongs to the NlpA lipoprotein family
JDY60_RS08720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JDY60_RS08725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JDY60_RS08745	COG2972	Histidine kinase
JDY60_RS08750	COG4753	response regulator
JDY60_RS08750	COG2207	Transcriptional regulator
JDY60_RS08760	COG1780	Probably involved in ribonucleotide reductase function
JDY60_RS08780	COG1438	arginine binding
JDY60_RS08805	COG1395	domain, Protein
JDY60_RS08820	COG2818	Glycosylase
JDY60_RS08850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JDY60_RS08855	COG0006	proline dipeptidase activity
JDY60_RS08860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JDY60_RS08865	COG1393	Belongs to the ArsC family
JDY60_RS08890	COG0285	dihydrofolate synthase activity
JDY60_RS08900	COG1454	alcohol dehydrogenase
JDY60_RS08910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JDY60_RS08915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JDY60_RS08925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JDY60_RS08930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JDY60_RS08945	COG1328	CTP reductase activity
JDY60_RS08965	COG0602	queuosine metabolic process
JDY60_RS09000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JDY60_RS09025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JDY60_RS09045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JDY60_RS09065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JDY60_RS09080	COG0201	protein transport
JDY60_RS09090	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JDY60_RS09095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JDY60_RS09105	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JDY60_RS09110	COG0202	RNA polymerase activity
JDY60_RS09120	COG3830	Belongs to the UPF0237 family
JDY60_RS09125	COG2848	UPF0210 protein
JDY60_RS09130	COG0588	phosphoglycerate mutase activity
JDY60_RS09135	COG1178	ABC-type Fe3 transport system permease component
JDY60_RS09140	COG3842	ATPase activity
JDY60_RS09145	COG1840	ABC-type Fe3 transport system, periplasmic component
JDY60_RS09165	COG1917	Cupin 2, conserved barrel domain protein
JDY60_RS09165	COG4977	sequence-specific DNA binding
JDY60_RS09185	COG2255	four-way junction helicase activity
JDY60_RS09195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JDY60_RS09200	COG4589	Belongs to the CDS family
JDY60_RS09205	COG0750	zinc metalloprotease
JDY60_RS09215	COG2723	6-phospho-beta-galactosidase activity
JDY60_RS09225	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JDY60_RS09235	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JDY60_RS09255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JDY60_RS09260	COG0765	amino acid transport
JDY60_RS09265	COG0765	amino acid transport
JDY60_RS09270	COG1126	abc transporter atp-binding protein
JDY60_RS09275	COG1523	belongs to the glycosyl hydrolase 13 family
JDY60_RS09300	COG0802	atpase or kinase
JDY60_RS09310	COG1316	TRANSCRIPTIONal
JDY60_RS09335	COG0534	Mate efflux family protein
JDY60_RS09345	COG0582	viral genome integration into host DNA
JDY60_RS09360	COG1396	sequence-specific DNA binding
JDY60_RS09485	COG0582	viral genome integration into host DNA