locus-tag	class	description
BWR56_RS00010	COG1475	DNA binding
BWR56_RS00015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWR56_RS00060	COG1511	domain protein
BWR56_RS00060	COG1511	domain protein
BWR56_RS00070	COG0488	(ABC) transporter
BWR56_RS00075	COG0180	Tryptophanyl-tRNA synthetase
BWR56_RS00080	COG0517	IMP dehydrogenase activity
BWR56_RS00080	COG0516	GMP reductase activity
BWR56_RS00090	COG2501	S4 domain
BWR56_RS00095	COG0612	Peptidase, M16
BWR56_RS00100	COG0612	Peptidase, M16
BWR56_RS00110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BWR56_RS00115	COG1122	ATPase activity
BWR56_RS00120	COG1122	ATPase activity
BWR56_RS00125	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BWR56_RS00130	COG1792	Involved in formation and maintenance of cell shape
BWR56_RS00140	COG3942	CHAP domain
BWR56_RS00145	COG2348	transferase activity, transferring amino-acyl groups
BWR56_RS00170	COG1739	Uncharacterized protein family UPF0029
BWR56_RS00175	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BWR56_RS00180	COG1040	competence protein
BWR56_RS00190	COG0183	Belongs to the thiolase family
BWR56_RS00195	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BWR56_RS00205	COG0305	Participates in initiation and elongation during chromosome replication
BWR56_RS00215	COG3942	CHAP domain
BWR56_RS00225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWR56_RS00225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWR56_RS00235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWR56_RS00240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWR56_RS00245	COG1116	anion transmembrane transporter activity
BWR56_RS00255	COG4974	Belongs to the 'phage' integrase family
BWR56_RS00350	COG4463	regulation of RNA biosynthetic process
BWR56_RS00355	COG0542	response to heat
BWR56_RS00360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BWR56_RS00365	COG3201	nicotinamide mononucleotide transporter
BWR56_RS00385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BWR56_RS00405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BWR56_RS00410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWR56_RS00425	COG1696	Membrane protein involved in D-alanine export
BWR56_RS00430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWR56_RS00435	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BWR56_RS00440	COG0737	Belongs to the 5'-nucleotidase family
BWR56_RS00445	COG1846	Transcriptional regulator
BWR56_RS00450	COG1121	(ABC) transporter
BWR56_RS00455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BWR56_RS00460	COG3443	Belongs to the bacterial solute-binding protein 9 family
BWR56_RS00460	COG0803	Belongs to the bacterial solute-binding protein 9 family
BWR56_RS00470	COG3537	Alpha-1,2-mannosidase
BWR56_RS00485	COG0383	alpha-mannosidase activity
BWR56_RS00500	COG4209	transmembrane transport
BWR56_RS00505	COG0395	ABC-type sugar transport system, permease component
BWR56_RS00510	COG1653	transport
BWR56_RS00555	COG2807	transmembrane transport
BWR56_RS00560	COG1216	Glycosyl transferase, family 2
BWR56_RS00580	COG0546	phosphoglycolate phosphatase activity
BWR56_RS00585	COG1760	l-serine dehydratase
BWR56_RS00590	COG1760	l-serine dehydratase
BWR56_RS00595	COG1388	LysM domain
BWR56_RS00595	COG3584	3D domain protein
BWR56_RS00615	COG1136	(ABC) transporter
BWR56_RS00615	COG0577	efflux transmembrane transporter activity
BWR56_RS00620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWR56_RS00645	COG0494	nUDIX hydrolase
BWR56_RS00650	COG0445	tRNA wobble uridine modification
BWR56_RS00680	COG1214	PFAM Peptidase M22, glycoprotease
BWR56_RS00730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWR56_RS00735	COG1464	Belongs to the NlpA lipoprotein family
BWR56_RS00745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BWR56_RS00755	COG1696	Membrane protein involved in D-alanine export
BWR56_RS00775	COG2972	Histidine kinase
BWR56_RS00780	COG2207	Transcriptional regulator
BWR56_RS00780	COG4753	response regulator
BWR56_RS00790	COG1780	Probably involved in ribonucleotide reductase function
BWR56_RS00810	COG1438	arginine binding
BWR56_RS00840	COG1395	domain, Protein
BWR56_RS00855	COG2818	Glycosylase
BWR56_RS00885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BWR56_RS00890	COG0006	proline dipeptidase activity
BWR56_RS00895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BWR56_RS00900	COG1393	Belongs to the ArsC family
BWR56_RS00925	COG0285	dihydrofolate synthase activity
BWR56_RS00935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWR56_RS00945	COG1328	CTP reductase activity
BWR56_RS00960	COG0602	queuosine metabolic process
BWR56_RS00995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BWR56_RS01010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BWR56_RS01020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BWR56_RS01040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BWR56_RS01060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BWR56_RS01075	COG0201	protein transport
BWR56_RS01085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BWR56_RS01090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BWR56_RS01100	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BWR56_RS01105	COG0202	RNA polymerase activity
BWR56_RS01115	COG3830	Belongs to the UPF0237 family
BWR56_RS01120	COG2848	UPF0210 protein
BWR56_RS01125	COG0588	phosphoglycerate mutase activity
BWR56_RS01145	COG2255	four-way junction helicase activity
BWR56_RS01155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BWR56_RS01160	COG4589	Belongs to the CDS family
BWR56_RS01165	COG0750	zinc metalloprotease
BWR56_RS01175	COG2723	6-phospho-beta-galactosidase activity
BWR56_RS01185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BWR56_RS01210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWR56_RS01215	COG0765	amino acid transport
BWR56_RS01220	COG0765	amino acid transport
BWR56_RS01225	COG1126	abc transporter atp-binding protein
BWR56_RS01235	COG1523	belongs to the glycosyl hydrolase 13 family
BWR56_RS01260	COG0802	atpase or kinase
BWR56_RS01270	COG1316	TRANSCRIPTIONal
BWR56_RS01290	COG0534	Mate efflux family protein
BWR56_RS01335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BWR56_RS01345	COG1461	Dihydroxyacetone kinase
BWR56_RS01365	COG1131	(ABC) transporter
BWR56_RS01375	COG4585	Histidine kinase
BWR56_RS01380	COG2197	response regulator
BWR56_RS01410	COG0028	Belongs to the TPP enzyme family
BWR56_RS01415	COG0440	acetolactate synthase activity
BWR56_RS01425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BWR56_RS01440	COG1126	abc transporter atp-binding protein
BWR56_RS01445	COG0765	amino acid transport
BWR56_RS01470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BWR56_RS01475	COG1882	Formate acetyltransferase
BWR56_RS01505	COG0366	Alpha amylase catalytic
BWR56_RS01510	COG4166	transmembrane transport
BWR56_RS01515	COG4166	transmembrane transport
BWR56_RS01525	COG4464	protein tyrosine phosphatase activity
BWR56_RS01530	COG3944	biosynthesis protein
BWR56_RS01535	COG0489	protein tyrosine kinase activity
BWR56_RS01550	COG0297	glycogen (starch) synthase activity
BWR56_RS01560	COG1442	glycosyl transferase family 8
BWR56_RS01560	COG1216	Glycosyl transferase, family 2
BWR56_RS01575	COG0562	UDP-galactopyranose mutase
BWR56_RS01580	COG0438	transferase activity, transferring glycosyl groups
BWR56_RS01585	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BWR56_RS01595	COG1088	dTDP-glucose 4,6-dehydratase activity
BWR56_RS01600	COG1091	dTDP-4-dehydrorhamnose reductase activity
BWR56_RS01605	COG0366	Alpha amylase catalytic
BWR56_RS01605	COG0366	Alpha amylase catalytic
BWR56_RS01645	COG0116	Belongs to the methyltransferase superfamily
BWR56_RS01655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BWR56_RS01660	COG0745	RESPONSE REGULATOR receiver
BWR56_RS01700	COG4585	Histidine kinase
BWR56_RS01705	COG2197	response regulator
BWR56_RS01715	COG0544	peptidyl-prolyl cis-trans isomerase activity
BWR56_RS01720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BWR56_RS01725	COG0681	Belongs to the peptidase S26 family
BWR56_RS01750	COG1115	amino acid carrier protein
BWR56_RS01775	COG0527	aspartate kinase activity
BWR56_RS01780	COG1024	Enoyl-CoA hydratase
BWR56_RS01785	COG1846	Transcriptional regulator
BWR56_RS01795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWR56_RS01805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BWR56_RS01810	COG1028	Short-chain dehydrogenase reductase Sdr
BWR56_RS01815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BWR56_RS01830	COG0439	Biotin carboxylase
BWR56_RS01835	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BWR56_RS01900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BWR56_RS01925	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BWR56_RS01930	COG0668	transmembrane transport
BWR56_RS01940	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BWR56_RS01945	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BWR56_RS01950	COG1534	Rna-binding protein
BWR56_RS01955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BWR56_RS01960	COG1713	HD superfamily hydrolase involved in NAD metabolism
BWR56_RS01970	COG0799	negative regulation of ribosome biogenesis
BWR56_RS01980	COG2226	methyltransferase
BWR56_RS02000	COG0194	GDP metabolic process
BWR56_RS02010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BWR56_RS02020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BWR56_RS02020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BWR56_RS02025	COG0631	protein serine/threonine phosphatase activity
BWR56_RS02030	COG2815	serine threonine protein kinase
BWR56_RS02030	COG0515	serine threonine protein kinase
BWR56_RS02045	COG3425	synthase
BWR56_RS02070	COG1609	Transcriptional regulator
BWR56_RS02075	COG1621	beta-fructofuranosidase activity
BWR56_RS02080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWR56_RS02080	COG2190	(PTS) system
BWR56_RS02080	COG1263	PTS System
BWR56_RS02085	COG1940	carbohydrate kinase activity
BWR56_RS02100	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BWR56_RS02110	COG0732	type I restriction modification DNA specificity domain
BWR56_RS02145	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
BWR56_RS02150	COG3620	sequence-specific DNA binding
BWR56_RS02155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BWR56_RS02165	COG1185	polyribonucleotide nucleotidyltransferase activity
BWR56_RS02170	COG1045	serine acetyltransferase
BWR56_RS02185	COG0215	cysteine-tRNA ligase activity
BWR56_RS02190	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BWR56_RS02200	COG3842	ATPase activity
BWR56_RS02225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BWR56_RS02245	COG3590	peptidase
BWR56_RS02285	COG0745	RESPONSE REGULATOR receiver
BWR56_RS02305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BWR56_RS02335	COG1959	2 iron, 2 sulfur cluster binding
BWR56_RS02345	COG0765	amino acid transport
BWR56_RS02350	COG0765	amino acid transport
BWR56_RS02355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWR56_RS02365	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BWR56_RS02365	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BWR56_RS02385	COG5549	protein import
BWR56_RS02385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWR56_RS02410	COG1573	uracil-dna glycosylase
BWR56_RS02415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWR56_RS02415	COG0425	Belongs to the sulfur carrier protein TusA family
BWR56_RS02420	COG1114	Component of the transport system for branched-chain amino acids
BWR56_RS02430	COG4808	Protein conserved in bacteria
BWR56_RS02435	COG1363	Peptidase, m42
BWR56_RS02460	COG2226	methyltransferase
BWR56_RS02465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BWR56_RS02475	COG3935	DnaD domain protein
BWR56_RS02480	COG0149	triose-phosphate isomerase activity
BWR56_RS02490	COG2824	Alkylphosphonate utilization operon protein PhnA
BWR56_RS02510	COG0351	phosphomethylpyrimidine kinase
BWR56_RS02515	COG4720	Psort location CytoplasmicMembrane, score
BWR56_RS02525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BWR56_RS02530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BWR56_RS02535	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BWR56_RS02550	COG4974	Belongs to the 'phage' integrase family
BWR56_RS02565	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BWR56_RS02575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWR56_RS02585	COG0006	proline dipeptidase activity
BWR56_RS02590	COG3442	glutamine amidotransferase
BWR56_RS02595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWR56_RS02600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWR56_RS02605	COG2223	nitrite transmembrane transporter activity
BWR56_RS02610	COG0513	Belongs to the DEAD box helicase family
BWR56_RS02615	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BWR56_RS02620	COG1335	isochorismatase
BWR56_RS02630	COG0577	efflux transmembrane transporter activity
BWR56_RS02635	COG1136	(ABC) transporter
BWR56_RS02640	COG0577	efflux transmembrane transporter activity
BWR56_RS02645	COG0745	RESPONSE REGULATOR receiver
BWR56_RS02650	COG5002	protein histidine kinase activity
BWR56_RS02655	COG0191	fructose-bisphosphate aldolase activity
BWR56_RS02660	COG0596	Alpha beta hydrolase
BWR56_RS02675	COG4555	ABC transporter
BWR56_RS02690	COG1404	Belongs to the peptidase S8 family
BWR56_RS02705	COG2247	cell wall binding repeat
BWR56_RS02705	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWR56_RS02710	COG0583	DNA-binding transcription factor activity
BWR56_RS02730	COG1187	pseudouridine synthase activity
BWR56_RS02735	COG1217	gtp-binding protein TYPA
BWR56_RS02755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BWR56_RS02770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWR56_RS02775	COG1126	abc transporter atp-binding protein
BWR56_RS02780	COG0765	amino acid transport
BWR56_RS02790	COG1304	FMN binding
BWR56_RS02805	COG4172	Belongs to the ABC transporter superfamily
BWR56_RS02815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BWR56_RS02825	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BWR56_RS02830	COG0352	thiamine-phosphate diphosphorylase activity
BWR56_RS02850	COG2217	Heavy metal translocating P-type atpase
BWR56_RS02855	COG0028	Belongs to the TPP enzyme family
BWR56_RS02875	COG1136	(ABC) transporter
BWR56_RS02890	COG2723	6-phospho-beta-galactosidase activity
BWR56_RS02895	COG1482	cell wall glycoprotein biosynthetic process
BWR56_RS02900	COG0733	neurotransmitter:sodium symporter activity
BWR56_RS02905	COG0789	Transcriptional regulator
BWR56_RS02915	COG2081	HI0933 family
BWR56_RS02920	COG1307	EDD domain protein, DegV family
BWR56_RS02930	COG2131	deaminase
BWR56_RS02935	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BWR56_RS02940	COG0740	serine-type endopeptidase activity
BWR56_RS02975	COG0617	tRNA 3'-terminal CCA addition
BWR56_RS02975	COG0517	IMP dehydrogenase activity
BWR56_RS02975	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BWR56_RS02980	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BWR56_RS02985	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BWR56_RS02990	COG2884	Cell division ATP-binding protein ftsE
BWR56_RS02995	COG2177	Part of the ABC transporter FtsEX involved in
BWR56_RS03000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWR56_RS03000	COG1263	PTS System
BWR56_RS03000	COG2190	(PTS) system
BWR56_RS03010	COG0513	Belongs to the DEAD box helicase family
BWR56_RS03040	COG0542	response to heat
BWR56_RS03045	COG4703	Protein of unknown function (DUF1797)
BWR56_RS03050	COG0765	amino acid transport
BWR56_RS03055	COG1126	abc transporter atp-binding protein
BWR56_RS03065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BWR56_RS03075	COG3250	beta-galactosidase activity
BWR56_RS03085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BWR56_RS03090	COG1199	ATP-dependent helicase activity
BWR56_RS03090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BWR56_RS03095	COG0772	Belongs to the SEDS family
BWR56_RS03100	COG0047	phosphoribosylformylglycinamidine synthase activity
BWR56_RS03110	COG0187	DNA topoisomerase II activity
BWR56_RS03120	COG0726	polysaccharide deacetylase
BWR56_RS03125	COG0656	L-ascorbic acid biosynthetic process
BWR56_RS03155	COG1053	succinate dehydrogenase
BWR56_RS03155	COG0431	NADPH-dependent FMN reductase
BWR56_RS03155	COG3976	FMN-binding domain protein
BWR56_RS03185	COG1272	protein, Hemolysin III
BWR56_RS03200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BWR56_RS03205	COG1393	Belongs to the ArsC family
BWR56_RS03215	COG1126	abc transporter atp-binding protein
BWR56_RS03225	COG0492	ferredoxin-NADP+ reductase activity
BWR56_RS03245	COG0561	phosphatase activity
BWR56_RS03265	COG1349	DNA-binding transcription factor activity
BWR56_RS03270	COG1105	Belongs to the carbohydrate kinase PfkB family
BWR56_RS03275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWR56_RS03275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWR56_RS03275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWR56_RS03280	COG1674	ftsk spoiiie
BWR56_RS03280	COG0697	spore germination
BWR56_RS03290	COG1104	cysteine desulfurase activity
BWR56_RS03315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWR56_RS03325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWR56_RS03330	COG0697	spore germination
BWR56_RS03345	COG1704	LemA family
BWR56_RS03355	COG0488	(ABC) transporter
BWR56_RS03370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BWR56_RS03385	COG0505	Belongs to the CarA family
BWR56_RS03410	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BWR56_RS03415	COG0716	FMN binding
BWR56_RS03420	COG1605	Chorismate mutase
BWR56_RS03420	COG0077	Prephenate dehydratase
BWR56_RS03425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BWR56_RS03430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BWR56_RS03485	COG1078	dGTPase activity
BWR56_RS03525	COG0583	DNA-binding transcription factor activity
BWR56_RS03530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BWR56_RS03535	COG0564	pseudouridine synthase activity
BWR56_RS03550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BWR56_RS03560	COG0470	DNA polymerase III
BWR56_RS03580	COG0528	UMP kinase activity
BWR56_RS03590	COG2996	Protein conserved in bacteria
BWR56_RS03595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BWR56_RS03595	COG0456	acetyltransferase
BWR56_RS03605	COG1702	phosphate starvation-inducible protein PhoH
BWR56_RS03610	COG0686	Belongs to the AlaDH PNT family
BWR56_RS03620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWR56_RS03625	COG1555	photosystem II stabilization
BWR56_RS03625	COG1596	polysaccharide export
BWR56_RS03630	COG0658	competence protein
BWR56_RS03630	COG2333	competence protein COMEC
BWR56_RS03640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BWR56_RS03645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BWR56_RS03650	COG0443	Heat shock 70 kDa protein
BWR56_RS03665	COG0543	2 iron, 2 sulfur cluster binding
BWR56_RS03670	COG0167	dihydroorotate dehydrogenase activity
BWR56_RS03675	COG4193	domain, Protein
BWR56_RS03675	COG5263	repeat protein
BWR56_RS03690	COG1028	Short-chain dehydrogenase reductase Sdr
BWR56_RS03720	COG1396	sequence-specific DNA binding
BWR56_RS03740	COG0745	RESPONSE REGULATOR receiver
BWR56_RS03745	COG5002	protein histidine kinase activity
BWR56_RS03760	COG1136	(ABC) transporter
BWR56_RS03785	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BWR56_RS03795	COG0813	purine-nucleoside phosphorylase activity
BWR56_RS03800	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BWR56_RS03810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BWR56_RS03820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BWR56_RS03825	COG0237	dephospho-CoA kinase activity
BWR56_RS03830	COG2814	Major facilitator Superfamily
BWR56_RS03835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BWR56_RS03845	COG0557	exoribonuclease II activity
BWR56_RS03855	COG0500	methyltransferase
BWR56_RS03855	COG3615	Tellurite resistance protein tehB
BWR56_RS03875	COG4122	O-methyltransferase activity
BWR56_RS03895	COG0772	Belongs to the SEDS family
BWR56_RS03900	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BWR56_RS03920	COG0358	DNA primase activity
BWR56_RS03925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BWR56_RS03930	COG2151	metal-sulfur cluster biosynthetic enzyme
BWR56_RS03935	COG0438	transferase activity, transferring glycosyl groups
BWR56_RS03940	COG0438	transferase activity, transferring glycosyl groups
BWR56_RS03965	COG1438	arginine binding
BWR56_RS03970	COG2936	dipeptidyl-peptidase activity
BWR56_RS03985	COG0469	pyruvate kinase activity
BWR56_RS03990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BWR56_RS04000	COG4109	DRTGG domain
BWR56_RS04005	COG0024	Methionine aminopeptidase
BWR56_RS04010	COG0785	Cytochrome C biogenesis protein
BWR56_RS04015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWR56_RS04020	COG1686	Belongs to the peptidase S11 family
BWR56_RS04025	COG0628	permease
BWR56_RS04040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BWR56_RS04045	COG2205	protein histidine kinase activity
BWR56_RS04060	COG1136	(ABC) transporter
BWR56_RS04080	COG2188	Transcriptional regulator
BWR56_RS04085	COG0826	peptidase U32
BWR56_RS04135	COG2706	6-phosphogluconolactonase activity
BWR56_RS04140	COG0628	permease
BWR56_RS04155	COG1126	abc transporter atp-binding protein
BWR56_RS04180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BWR56_RS04195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BWR56_RS04200	COG0494	nUDIX hydrolase
BWR56_RS04220	COG2176	DNA-directed DNA polymerase activity
BWR56_RS04225	COG0584	glycerophosphoryl diester phosphodiesterase
BWR56_RS04235	COG2822	iron ion transport
BWR56_RS04240	COG2837	iron assimilation
BWR56_RS04245	COG0672	)-iron permease
BWR56_RS04250	COG0805	protein transport
BWR56_RS04255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BWR56_RS04265	COG1063	alcohol dehydrogenase
BWR56_RS04280	COG4750	Nucleotidyl transferase
BWR56_RS04295	COG3775	system Galactitol-specific IIC component
BWR56_RS04320	COG3684	Belongs to the aldolase LacD family
BWR56_RS04325	COG3711	transcriptional antiterminator
BWR56_RS04340	COG2723	6-phospho-beta-galactosidase activity
BWR56_RS04350	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWR56_RS04355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWR56_RS04360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BWR56_RS04365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWR56_RS04380	COG3443	Belongs to the bacterial solute-binding protein 9 family
BWR56_RS04380	COG0803	Belongs to the bacterial solute-binding protein 9 family
BWR56_RS04390	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWR56_RS04400	COG0681	Belongs to the peptidase S26 family
BWR56_RS04410	COG4509	Sortase family
BWR56_RS04425	COG1970	mechanosensitive ion channel activity
BWR56_RS04435	COG4708	membrane
BWR56_RS04445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWR56_RS04455	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BWR56_RS04460	COG1942	4-Oxalocrotonate Tautomerase
BWR56_RS04465	COG1435	thymidine kinase activity
BWR56_RS04480	COG2890	protein-(glutamine-N5) methyltransferase activity
BWR56_RS04505	COG0741	lytic transglycosylase activity
BWR56_RS04515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BWR56_RS04530	COG0488	(ABC) transporter
BWR56_RS04580	COG1597	lipid kinase activity
BWR56_RS04585	COG0135	phosphoribosylanthranilate isomerase activity
BWR56_RS04615	COG1982	Orn Lys Arg decarboxylase major
BWR56_RS04620	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BWR56_RS04640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWR56_RS04650	COG0745	RESPONSE REGULATOR receiver
BWR56_RS04655	COG2205	protein histidine kinase activity
BWR56_RS04665	COG1131	(ABC) transporter
BWR56_RS04670	COG0561	phosphatase activity
BWR56_RS04680	COG1673	EVE domain
BWR56_RS04710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BWR56_RS04720	COG0038	chloride channel
BWR56_RS04735	COG0095	Lipoate-protein ligase
BWR56_RS04740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWR56_RS04745	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWR56_RS04750	COG0022	dehydrogenase e1 component
BWR56_RS04755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BWR56_RS04760	COG0534	Mate efflux family protein
BWR56_RS04765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BWR56_RS04770	COG1051	belongs to the nudix hydrolase family
BWR56_RS04790	COG1011	Hydrolase
BWR56_RS04825	COG3708	Transcriptional regulator
BWR56_RS04825	COG2207	Transcriptional regulator
BWR56_RS04855	COG0560	Phosphoserine phosphatase
BWR56_RS04865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWR56_RS04875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BWR56_RS04880	COG1012	belongs to the aldehyde dehydrogenase family
BWR56_RS04885	COG1523	belongs to the glycosyl hydrolase 13 family
BWR56_RS04905	COG0488	(ABC) transporter
BWR56_RS04915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWR56_RS04925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWR56_RS04930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BWR56_RS04940	COG0745	RESPONSE REGULATOR receiver
BWR56_RS04945	COG1194	a g-specific adenine glycosylase
BWR56_RS04950	COG0280	phosphate acetyltransferase
BWR56_RS04955	COG0564	pseudouridine synthase activity
BWR56_RS04965	COG2357	RelA SpoT domain protein
BWR56_RS04975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BWR56_RS04980	COG1104	cysteine desulfurase activity
BWR56_RS05000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BWR56_RS05020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BWR56_RS05025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BWR56_RS05030	COG4684	Psort location CytoplasmicMembrane, score
BWR56_RS05045	COG1827	regulation of RNA biosynthetic process
BWR56_RS05115	COG0765	amino acid transport
BWR56_RS05120	COG1126	abc transporter atp-binding protein
BWR56_RS05125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BWR56_RS05130	COG0552	protein localization to endoplasmic reticulum
BWR56_RS05135	COG0561	phosphatase activity
BWR56_RS05140	COG0561	phosphatase activity
BWR56_RS05150	COG0577	efflux transmembrane transporter activity
BWR56_RS05155	COG1136	(ABC) transporter
BWR56_RS05170	COG2183	response to ionizing radiation
BWR56_RS05180	COG0701	Predicted permease
BWR56_RS05185	COG3689	TIGRFAM TIGR03943 family protein
BWR56_RS05190	COG0196	riboflavin kinase activity
BWR56_RS05195	COG1196	nuclear chromosome segregation
BWR56_RS05220	COG1401	restriction endodeoxyribonuclease activity
BWR56_RS05230	COG0066	3-isopropylmalate dehydratase activity
BWR56_RS05245	COG0473	3-isopropylmalate dehydrogenase activity
BWR56_RS05260	COG3142	Participates in the control of copper homeostasis
BWR56_RS05265	COG2832	Protein of unknown function (DUF454)
BWR56_RS05270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWR56_RS05275	COG0758	DNA mediated transformation
BWR56_RS05290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BWR56_RS05295	COG0497	DNA recombination
BWR56_RS05300	COG1438	arginine binding
BWR56_RS05305	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BWR56_RS05330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BWR56_RS05355	COG3764	Sortase (surface protein transpeptidase)
BWR56_RS05360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BWR56_RS05365	COG0039	L-malate dehydrogenase activity
BWR56_RS05375	COG1307	EDD domain protein, DegV family
BWR56_RS05380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWR56_RS05385	COG0531	amino acid
BWR56_RS05395	COG0719	Fe-S assembly protein
BWR56_RS05405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BWR56_RS05410	COG0719	Fe-S assembly protein
BWR56_RS05425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BWR56_RS05430	COG1956	GAF domain-containing protein
BWR56_RS05435	COG0539	negative regulation of cytoplasmic translation
BWR56_RS05455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BWR56_RS05460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BWR56_RS05485	COG3339	Conserved Protein
BWR56_RS05490	COG0187	DNA topoisomerase II activity
BWR56_RS05500	COG1079	Belongs to the binding-protein-dependent transport system permease family
BWR56_RS05505	COG4603	Belongs to the binding-protein-dependent transport system permease family
BWR56_RS05510	COG3845	ABC transporter
BWR56_RS05515	COG1744	ABC transporter substrate-binding protein PnrA-like
BWR56_RS05520	COG0295	cytidine deaminase activity
BWR56_RS05530	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BWR56_RS05535	COG2813	Specifically methylates the guanine in position
BWR56_RS05560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWR56_RS05560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWR56_RS05565	COG0577	efflux transmembrane transporter activity
BWR56_RS05570	COG1136	(ABC) transporter
BWR56_RS05575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWR56_RS05580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWR56_RS05585	COG1268	BioY protein
BWR56_RS05600	COG4443	Transcriptional Coactivator p15 (PC4)
BWR56_RS05610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BWR56_RS05610	COG1328	CTP reductase activity
BWR56_RS05630	COG1837	Belongs to the UPF0109 family
BWR56_RS05650	COG0488	(ABC) transporter
BWR56_RS05660	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BWR56_RS05665	COG4470	Protein conserved in bacteria
BWR56_RS05670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BWR56_RS05680	COG0167	dihydroorotate dehydrogenase activity
BWR56_RS05685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BWR56_RS05700	COG5504	Zn-dependent protease
BWR56_RS05705	COG4974	Belongs to the 'phage' integrase family
BWR56_RS05720	COG1396	sequence-specific DNA binding
BWR56_RS05725	COG1132	(ABC) transporter
BWR56_RS05740	COG1131	(ABC) transporter
BWR56_RS05755	COG3843	relaxase mobilization nuclease domain protein
BWR56_RS05800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BWR56_RS05810	COG0542	response to heat
BWR56_RS05815	COG1396	sequence-specific DNA binding
BWR56_RS05830	COG1131	(ABC) transporter
BWR56_RS05880	COG1396	sequence-specific DNA binding
BWR56_RS05890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWR56_RS05895	COG1132	(ABC) transporter
BWR56_RS06020	COG0270	DNA (cytosine-5-)-methyltransferase activity
BWR56_RS06035	COG0222	ribosome binding
BWR56_RS06040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BWR56_RS06050	COG0402	S-adenosylhomocysteine deaminase activity
BWR56_RS06065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWR56_RS06065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWR56_RS06100	COG3475	LICD family
BWR56_RS06105	COG3475	LICD family
BWR56_RS06110	COG1215	transferase activity, transferring glycosyl groups
BWR56_RS06115	COG3475	LICD family
BWR56_RS06125	COG0077	Prephenate dehydratase
BWR56_RS06130	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BWR56_RS06140	COG3679	Belongs to the UPF0342 family
BWR56_RS06145	COG0287	Prephenate dehydrogenase
BWR56_RS06170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BWR56_RS06180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BWR56_RS06205	COG1567	CRISPR-associated RAMP protein, Csm4 family
BWR56_RS06210	COG1337	RAMP superfamily
BWR56_RS06250	COG1177	transmembrane transport
BWR56_RS06255	COG3842	ATPase activity
BWR56_RS06265	COG2207	Transcriptional regulator
BWR56_RS06275	COG1609	Transcriptional regulator
BWR56_RS06290	COG3527	Alpha-acetolactate decarboxylase
BWR56_RS06295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWR56_RS06300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWR56_RS06305	COG0494	nUDIX hydrolase
BWR56_RS06310	COG0704	Plays a role in the regulation of phosphate uptake
BWR56_RS06315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BWR56_RS06320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BWR56_RS06325	COG0581	inorganic phosphate transmembrane transporter activity
BWR56_RS06330	COG0573	inorganic phosphate transmembrane transporter activity
BWR56_RS06335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BWR56_RS06340	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BWR56_RS06340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BWR56_RS06345	COG0483	inositol monophosphate 1-phosphatase activity
BWR56_RS06355	COG1393	Belongs to the ArsC family
BWR56_RS06370	COG0647	UMP catabolic process
BWR56_RS06380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BWR56_RS06410	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BWR56_RS06435	COG0025	NhaP-type Na H and K H
BWR56_RS06445	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BWR56_RS06450	COG1242	4 iron, 4 sulfur cluster binding
BWR56_RS06460	COG2226	methyltransferase
BWR56_RS06475	COG3250	beta-galactosidase activity
BWR56_RS06480	COG0300	oxidoreductase activity
BWR56_RS06495	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BWR56_RS06500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BWR56_RS06520	COG1940	carbohydrate kinase activity
BWR56_RS06540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWR56_RS06545	COG3064	Membrane
BWR56_RS06555	COG2972	Histidine kinase
BWR56_RS06560	COG2207	Transcriptional regulator
BWR56_RS06560	COG4753	response regulator
BWR56_RS06565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWR56_RS06565	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWR56_RS06570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWR56_RS06575	COG0785	Cytochrome C biogenesis protein
BWR56_RS06580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWR56_RS06590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BWR56_RS06610	COG0454	-acetyltransferase
BWR56_RS06615	COG1113	amino acid transport
BWR56_RS06625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BWR56_RS06650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BWR56_RS06655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BWR56_RS06660	COG0626	cystathionine gamma-synthase activity
BWR56_RS06665	COG4166	transmembrane transport
BWR56_RS06670	COG2244	polysaccharide biosynthetic process
BWR56_RS06675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BWR56_RS06700	COG2827	Endonuclease containing a URI domain
BWR56_RS06705	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BWR56_RS06710	COG1098	S1 RNA binding domain
BWR56_RS06720	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BWR56_RS06725	COG1215	transferase activity, transferring glycosyl groups
BWR56_RS06735	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BWR56_RS06745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BWR56_RS06750	COG0629	single-stranded DNA binding
BWR56_RS06755	COG0360	Binds together with S18 to 16S ribosomal RNA
BWR56_RS06760	COG0017	Asparaginyl-tRNA synthetase
BWR56_RS06765	COG0436	Aminotransferase
BWR56_RS06775	COG1846	Transcriptional regulator
BWR56_RS06785	COG3022	response to hydroperoxide
BWR56_RS06795	COG0242	peptide deformylase activity
BWR56_RS06805	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BWR56_RS06815	COG0488	(ABC) transporter
BWR56_RS06820	COG0617	tRNA 3'-terminal CCA addition
BWR56_RS06830	COG1307	EDD domain protein, DegV family
BWR56_RS06860	COG0492	ferredoxin-NADP+ reductase activity
BWR56_RS06870	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BWR56_RS06880	COG0251	oxidation-reduction process
BWR56_RS06900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BWR56_RS06920	COG0463	Glycosyl transferase, family 2
BWR56_RS06925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWR56_RS06930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWR56_RS06935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BWR56_RS06940	COG2384	SAM-dependent methyltransferase
BWR56_RS06945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BWR56_RS06950	COG0204	Acyl-transferase
BWR56_RS06970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWR56_RS06995	COG3583	domain protein
BWR56_RS06995	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BWR56_RS07005	COG3583	domain protein
BWR56_RS07010	COG3583	domain protein
BWR56_RS07010	COG3583	domain protein
BWR56_RS07020	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BWR56_RS07025	COG3599	regulation of cell shape
BWR56_RS07030	COG3599	regulation of cell shape
BWR56_RS07050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BWR56_RS07070	COG1051	belongs to the nudix hydrolase family
BWR56_RS07075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWR56_RS07090	COG0768	penicillin binding
BWR56_RS07100	COG2226	methyltransferase
BWR56_RS07110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWR56_RS07120	COG2731	YhcH YjgK YiaL family protein
BWR56_RS07125	COG0395	ABC-type sugar transport system, permease component
BWR56_RS07130	COG1175	transmembrane transport
BWR56_RS07155	COG3458	cephalosporin-C deacetylase activity
BWR56_RS07170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BWR56_RS07185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWR56_RS07190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BWR56_RS07225	COG0778	Nitroreductase
BWR56_RS07230	COG1484	DNA-dependent DNA replication
BWR56_RS07245	COG1725	Transcriptional regulator
BWR56_RS07250	COG1131	(ABC) transporter
BWR56_RS07260	COG1136	(ABC) transporter
BWR56_RS07265	COG1346	cytolysis
BWR56_RS07270	COG1380	Effector of murein hydrolase LrgA
BWR56_RS07285	COG3118	belongs to the thioredoxin family
BWR56_RS07290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWR56_RS07300	COG1164	Oligoendopeptidase f
BWR56_RS07305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BWR56_RS07310	COG2264	protein methyltransferase activity
BWR56_RS07320	COG1051	belongs to the nudix hydrolase family
BWR56_RS07335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BWR56_RS07345	COG3711	transcriptional antiterminator
BWR56_RS07350	COG2261	transglycosylase associated protein
BWR56_RS07370	COG3237	CsbD-like
BWR56_RS07385	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BWR56_RS07395	COG0159	tryptophan synthase activity
BWR56_RS07405	COG0135	phosphoribosylanthranilate isomerase activity
BWR56_RS07420	COG0512	Glutamine amidotransferase of anthranilate synthase
BWR56_RS07425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWR56_RS07430	COG0133	tryptophan synthase activity
BWR56_RS07435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BWR56_RS07440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWR56_RS07450	COG1132	(ABC) transporter
BWR56_RS07455	COG1132	(ABC) transporter
BWR56_RS07460	COG2323	membrane
BWR56_RS07470	COG0708	Exodeoxyribonuclease III
BWR56_RS07490	COG2233	PERMEase
BWR56_RS07500	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BWR56_RS07505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWR56_RS07510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BWR56_RS07515	COG1609	Transcriptional regulator
BWR56_RS07520	COG1230	cation diffusion facilitator family transporter
BWR56_RS07535	COG3201	nicotinamide mononucleotide transporter
BWR56_RS07540	COG1174	glycine betaine transport
BWR56_RS07690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BWR56_RS07725	COG4221	oxidoreductase activity
BWR56_RS07730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWR56_RS07735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWR56_RS07750	COG0504	CTP synthase activity
BWR56_RS07780	COG0525	valine-tRNA ligase activity
BWR56_RS07790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWR56_RS07840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BWR56_RS07845	COG0195	Participates in both transcription termination and antitermination
BWR56_RS07865	COG1266	CAAX protease self-immunity
BWR56_RS07875	COG1266	CAAX protease self-immunity
BWR56_RS07910	COG3290	protein histidine kinase activity
BWR56_RS07935	COG1131	(ABC) transporter
BWR56_RS07940	COG0537	adenosine 5'-monophosphoramidase activity
BWR56_RS07955	COG0484	heat shock protein binding
BWR56_RS07970	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BWR56_RS07995	COG0174	glutamine synthetase
BWR56_RS08000	COG0789	Transcriptional regulator
BWR56_RS08010	COG0126	phosphoglycerate kinase activity
BWR56_RS08025	COG0366	Alpha amylase catalytic
BWR56_RS08040	COG1363	Peptidase, m42
BWR56_RS08050	COG1187	pseudouridine synthase activity
BWR56_RS08080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BWR56_RS08105	COG0768	penicillin binding
BWR56_RS08110	COG4839	cell division protein FtsL
BWR56_RS08180	COG0386	Belongs to the glutathione peroxidase family
BWR56_RS08185	COG0366	Alpha amylase catalytic
BWR56_RS08205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BWR56_RS08210	COG3620	sequence-specific DNA binding
BWR56_RS08220	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BWR56_RS08240	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BWR56_RS08245	COG1668	transmembrane transport
BWR56_RS08250	COG4152	abc transporter atp-binding protein
BWR56_RS08260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWR56_RS08260	COG0072	phenylalanine-tRNA ligase activity
BWR56_RS08270	COG0671	phosphoesterase, PA-phosphatase related
BWR56_RS08275	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BWR56_RS08290	COG0569	domain protein
BWR56_RS08295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWR56_RS08300	COG4608	Belongs to the ABC transporter superfamily
BWR56_RS08305	COG0444	Belongs to the ABC transporter superfamily
BWR56_RS08310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWR56_RS08315	COG0601	transmembrane transport
BWR56_RS08320	COG4166	transmembrane transport
BWR56_RS08330	COG1253	flavin adenine dinucleotide binding
BWR56_RS08345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BWR56_RS08355	COG3480	Lon protease (S16) C-terminal proteolytic domain
BWR56_RS08365	COG0742	ribosomal rna small subunit methyltransferase
BWR56_RS08380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWR56_RS08385	COG1254	Belongs to the acylphosphatase family
BWR56_RS08395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BWR56_RS08405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BWR56_RS08410	COG3481	metal-dependent phosphohydrolase, HD sub domain
BWR56_RS08420	COG1564	THIamine pyrophosphokinase
BWR56_RS08430	COG1162	GTPase activity
BWR56_RS08450	COG0084	hydrolase, TatD family'
BWR56_RS08455	COG0582	viral genome integration into host DNA
BWR56_RS08510	COG0531	amino acid
BWR56_RS08520	COG0436	Aminotransferase
BWR56_RS08530	COG0589	response to stress
BWR56_RS08535	COG0561	phosphatase activity
BWR56_RS08540	COG0252	asparaginase activity
BWR56_RS08545	COG1609	Transcriptional regulator
BWR56_RS08560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BWR56_RS08560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BWR56_RS08570	COG0285	dihydrofolate synthase activity
BWR56_RS08575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BWR56_RS08585	COG2252	PERMEase
BWR56_RS08590	COG0561	phosphatase activity
BWR56_RS08600	COG3715	PTS system
BWR56_RS08605	COG3716	PTS system mannose fructose sorbose family IID component
BWR56_RS08610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BWR56_RS08615	COG3579	cysteine-type endopeptidase activity
BWR56_RS08625	COG1187	pseudouridine synthase activity
BWR56_RS08630	COG2261	transglycosylase associated protein
BWR56_RS08635	COG2309	aminopeptidase activity
BWR56_RS08655	COG0419	ATPase involved in DNA repair
BWR56_RS08670	COG2176	DNA-directed DNA polymerase activity
BWR56_RS08765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BWR56_RS08770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWR56_RS08785	COG1454	alcohol dehydrogenase
BWR56_RS08785	COG1012	belongs to the aldehyde dehydrogenase family
BWR56_RS08795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BWR56_RS08805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BWR56_RS08815	COG1847	R3H domain protein
BWR56_RS08820	COG0706	membrane insertase activity
BWR56_RS08865	COG4537	Required for transformation and DNA binding
BWR56_RS08870	COG1459	type II secretion system
BWR56_RS08875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWR56_RS08910	COG0546	phosphoglycolate phosphatase activity
BWR56_RS08915	COG0534	Mate efflux family protein
BWR56_RS08920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BWR56_RS09030	COG0166	Belongs to the GPI family
BWR56_RS09040	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BWR56_RS09045	COG1132	(ABC) transporter
BWR56_RS09050	COG1132	(ABC) transporter
BWR56_RS09060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BWR56_RS09075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BWR56_RS09095	COG4499	WXG100 protein secretion system (Wss), protein YukC
BWR56_RS09095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWR56_RS09105	COG2226	methyltransferase
BWR56_RS09110	COG0058	SHG alpha-glucan phosphorylase activity
BWR56_RS09115	COG1640	4-alpha-glucanotransferase
BWR56_RS09120	COG2182	Extracellular solute-binding protein
BWR56_RS09125	COG1175	transmembrane transport
BWR56_RS09130	COG3833	ABC-type maltose transport systems, permease component
BWR56_RS09135	COG5521	maltodextrose utilization protein MalA
BWR56_RS09140	COG1609	Transcriptional regulator
BWR56_RS09145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWR56_RS09195	COG1476	TRANSCRIPTIONal
BWR56_RS09205	COG0124	histidyl-tRNA synthetase
BWR56_RS09220	COG2151	metal-sulfur cluster biosynthetic enzyme
BWR56_RS09235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BWR56_RS09250	COG4842	Belongs to the WXG100 family
BWR56_RS09265	COG4499	WXG100 protein secretion system (Wss), protein YukC
BWR56_RS09270	COG1674	ftsk spoiiie
BWR56_RS09380	COG5002	protein histidine kinase activity
BWR56_RS09385	COG0745	RESPONSE REGULATOR receiver
BWR56_RS09400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWR56_RS09415	COG1309	transcriptional regulator
BWR56_RS09435	COG0110	maltose O-acetyltransferase activity
BWR56_RS09440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWR56_RS09440	COG0425	Belongs to the sulfur carrier protein TusA family
BWR56_RS09450	COG0425	Belongs to the sulfur carrier protein TusA family
BWR56_RS09450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWR56_RS09455	COG1937	Protein conserved in bacteria
BWR56_RS09485	COG2514	catechol 2,3-dioxygenase activity
BWR56_RS09495	COG3684	Belongs to the aldolase LacD family
BWR56_RS09500	COG2222	sugar isomerase
BWR56_RS09510	COG3716	PTS system mannose fructose sorbose family IID component
BWR56_RS09515	COG3715	PTS system
BWR56_RS09520	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWR56_RS09535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BWR56_RS09535	COG3583	domain protein
BWR56_RS09535	COG3064	Membrane
BWR56_RS09540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BWR56_RS09545	COG0515	serine threonine protein kinase
BWR56_RS09545	COG2815	serine threonine protein kinase
BWR56_RS09560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BWR56_RS09575	COG0151	Belongs to the GarS family
BWR56_RS09580	COG0138	bifunctional purine biosynthesis protein purh
BWR56_RS09590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BWR56_RS09595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BWR56_RS09605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BWR56_RS09620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BWR56_RS09625	COG2274	protein secretion by the type I secretion system
BWR56_RS09660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWR56_RS09675	COG0436	Aminotransferase
BWR56_RS09680	COG2855	membrane
BWR56_RS09685	COG1832	CoA-binding protein
BWR56_RS09690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BWR56_RS09700	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BWR56_RS09715	COG0756	dUTP diphosphatase activity
BWR56_RS09775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BWR56_RS09780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWR56_RS09785	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BWR56_RS09805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BWR56_RS09810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BWR56_RS09820	COG0012	GTP binding
BWR56_RS09830	COG0592	DNA-directed DNA polymerase activity