locus-tag	class	description
KQ224_RS00015	COG0270	DNA (cytosine-5-)-methyltransferase activity
KQ224_RS00380	COG1396	sequence-specific DNA binding
KQ224_RS00385	COG0542	response to heat
KQ224_RS00390	COG0613	PHP domain protein
KQ224_RS00405	COG3843	relaxase mobilization nuclease domain protein
KQ224_RS00570	COG1396	sequence-specific DNA binding
KQ224_RS00580	COG4974	Belongs to the 'phage' integrase family
KQ224_RS00600	COG1131	(ABC) transporter
KQ224_RS00630	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KQ224_RS00635	COG1074	ATP-dependent DNA helicase activity
KQ224_RS00650	COG1104	cysteine desulfurase activity
KQ224_RS00655	COG0301	tRNA thio-modification
KQ224_RS00660	COG1114	Component of the transport system for branched-chain amino acids
KQ224_RS00665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KQ224_RS00670	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KQ224_RS00675	COG0583	DNA-binding transcription factor activity
KQ224_RS00685	COG0564	pseudouridine synthase activity
KQ224_RS00690	COG2824	Alkylphosphonate utilization operon protein PhnA
KQ224_RS00700	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KQ224_RS00705	COG0540	Belongs to the ATCase OTCase family
KQ224_RS00710	COG0505	Belongs to the CarA family
KQ224_RS00720	COG2136	Putative SAM-dependent methyltransferase
KQ224_RS00720	COG2521	methyltransferase
KQ224_RS00725	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KQ224_RS00735	COG0228	four-way junction DNA binding
KQ224_RS00750	COG1132	(ABC) transporter
KQ224_RS00755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KQ224_RS00760	COG0336	Belongs to the RNA methyltransferase TrmD family
KQ224_RS00770	COG0460	homoserine dehydrogenase
KQ224_RS00775	COG0083	homoserine kinase activity
KQ224_RS00780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KQ224_RS00785	COG3842	ATPase activity
KQ224_RS00790	COG1176	ABC-type spermidine putrescine transport system, permease component I
KQ224_RS00795	COG1177	transmembrane transport
KQ224_RS00805	COG0038	chloride channel
KQ224_RS00810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KQ224_RS00825	COG0534	Mate efflux family protein
KQ224_RS00830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KQ224_RS00835	COG1349	DNA-binding transcription factor activity
KQ224_RS00840	COG1105	Belongs to the carbohydrate kinase PfkB family
KQ224_RS00845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ224_RS00845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ224_RS00845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ224_RS00855	COG1307	EDD domain protein, DegV family
KQ224_RS00860	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KQ224_RS00865	COG0617	tRNA 3'-terminal CCA addition
KQ224_RS00870	COG0488	(ABC) transporter
KQ224_RS00880	COG1940	carbohydrate kinase activity
KQ224_RS00895	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KQ224_RS00900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KQ224_RS00905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KQ224_RS00920	COG0481	GTPase activity
KQ224_RS00945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KQ224_RS00950	COG2890	protein-(glutamine-N5) methyltransferase activity
KQ224_RS00955	COG0009	L-threonylcarbamoyladenylate synthase
KQ224_RS00960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KQ224_RS00970	COG0741	lytic transglycosylase activity
KQ224_RS01010	COG0366	Alpha amylase catalytic
KQ224_RS01015	COG4221	oxidoreductase activity
KQ224_RS01040	COG0187	DNA topoisomerase II activity
KQ224_RS01075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KQ224_RS01095	COG0539	negative regulation of cytoplasmic translation
KQ224_RS01110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ224_RS01115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ224_RS01125	COG0297	glycogen (starch) synthase activity
KQ224_RS01135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KQ224_RS01145	COG0543	2 iron, 2 sulfur cluster binding
KQ224_RS01150	COG0167	dihydroorotate dehydrogenase activity
KQ224_RS01155	COG0284	orotidine-5'-phosphate decarboxylase activity
KQ224_RS01170	COG0463	Glycosyl transferase, family 2
KQ224_RS01175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KQ224_RS01185	COG0737	Belongs to the 5'-nucleotidase family
KQ224_RS01190	COG0424	maF-like protein
KQ224_RS01210	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KQ224_RS01215	COG3708	Transcriptional regulator
KQ224_RS01215	COG2207	Transcriptional regulator
KQ224_RS01225	COG2382	esterase
KQ224_RS01250	COG1136	(ABC) transporter
KQ224_RS01255	COG0577	efflux transmembrane transporter activity
KQ224_RS01270	COG0745	RESPONSE REGULATOR receiver
KQ224_RS01285	COG4974	Belongs to the 'phage' integrase family
KQ224_RS01315	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KQ224_RS01320	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KQ224_RS01325	COG2188	Transcriptional regulator
KQ224_RS01330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ224_RS01330	COG0519	Catalyzes the synthesis of GMP from XMP
KQ224_RS01350	COG2207	Transcriptional regulator
KQ224_RS01350	COG3708	Transcriptional regulator
KQ224_RS01370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ224_RS01375	COG3620	sequence-specific DNA binding
KQ224_RS01390	COG1126	abc transporter atp-binding protein
KQ224_RS01405	COG0488	(ABC) transporter
KQ224_RS01410	COG2873	o-acetylhomoserine
KQ224_RS01430	COG1396	sequence-specific DNA binding
KQ224_RS01435	COG1194	a g-specific adenine glycosylase
KQ224_RS01450	COG1132	(ABC) transporter
KQ224_RS01460	COG0280	phosphate acetyltransferase
KQ224_RS01465	COG0564	pseudouridine synthase activity
KQ224_RS01470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KQ224_RS01475	COG2357	RelA SpoT domain protein
KQ224_RS01485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ224_RS01490	COG1104	cysteine desulfurase activity
KQ224_RS01505	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KQ224_RS01510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KQ224_RS01520	COG3764	Sortase (surface protein transpeptidase)
KQ224_RS01525	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KQ224_RS01530	COG0039	L-malate dehydrogenase activity
KQ224_RS01535	COG1079	Belongs to the binding-protein-dependent transport system permease family
KQ224_RS01540	COG4603	Belongs to the binding-protein-dependent transport system permease family
KQ224_RS01545	COG3845	ABC transporter
KQ224_RS01550	COG1744	ABC transporter substrate-binding protein PnrA-like
KQ224_RS01555	COG0295	cytidine deaminase activity
KQ224_RS01565	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KQ224_RS01570	COG2813	Specifically methylates the guanine in position
KQ224_RS01575	COG1072	(Pantothenic acid kinase))
KQ224_RS01580	COG0268	Binds directly to 16S ribosomal RNA
KQ224_RS01590	COG5002	protein histidine kinase activity
KQ224_RS01595	COG0745	RESPONSE REGULATOR receiver
KQ224_RS01615	COG0463	Glycosyl transferase, family 2
KQ224_RS01630	COG1368	sulfuric ester hydrolase activity
KQ224_RS01655	COG1442	glycosyl transferase family 8
KQ224_RS01655	COG1216	Glycosyl transferase, family 2
KQ224_RS01665	COG1705	Flagellar rod assembly protein muramidase FlgJ
KQ224_RS01670	COG0860	N-Acetylmuramoyl-L-alanine amidase
KQ224_RS01675	COG1091	dTDP-4-dehydrorhamnose reductase activity
KQ224_RS01680	COG1088	dTDP-glucose 4,6-dehydratase activity
KQ224_RS01695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KQ224_RS01705	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KQ224_RS01710	COG2384	SAM-dependent methyltransferase
KQ224_RS01720	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KQ224_RS01725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KQ224_RS01735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KQ224_RS01735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KQ224_RS01740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ224_RS01745	COG0300	oxidoreductase activity
KQ224_RS01750	COG1234	tRNA 3'-trailer cleavage
KQ224_RS01760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KQ224_RS01765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KQ224_RS01775	COG2807	transmembrane transport
KQ224_RS01790	COG1011	Hydrolase
KQ224_RS01805	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KQ224_RS01835	COG1164	Oligoendopeptidase f
KQ224_RS01845	COG0346	lactoylglutathione lyase activity
KQ224_RS01850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KQ224_RS01855	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KQ224_RS01860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KQ224_RS01870	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ224_RS01875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ224_RS01880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KQ224_RS01910	COG0732	type I restriction modification DNA specificity domain
KQ224_RS01920	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KQ224_RS01925	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KQ224_RS01935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KQ224_RS01940	COG4684	Psort location CytoplasmicMembrane, score
KQ224_RS01950	COG0456	acetyltransferase
KQ224_RS01970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ224_RS01990	COG2608	mercury ion transmembrane transporter activity
KQ224_RS02005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ224_RS02035	COG0415	Belongs to the DNA photolyase family
KQ224_RS02055	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KQ224_RS02165	COG0488	(ABC) transporter
KQ224_RS02190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KQ224_RS02200	COG2226	methyltransferase
KQ224_RS02225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KQ224_RS02325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ224_RS02365	COG2261	transglycosylase associated protein
KQ224_RS02395	COG0789	Transcriptional regulator
KQ224_RS02400	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KQ224_RS02410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KQ224_RS02410	COG0456	acetyltransferase
KQ224_RS02425	COG0488	(ABC) transporter
KQ224_RS02440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KQ224_RS02450	COG0077	Prephenate dehydratase
KQ224_RS02455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KQ224_RS02465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KQ224_RS02470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KQ224_RS02475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KQ224_RS02480	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KQ224_RS02485	COG1116	anion transmembrane transporter activity
KQ224_RS02485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ224_RS02490	COG4120	Belongs to the binding-protein-dependent transport system permease family
KQ224_RS02505	COG3679	Belongs to the UPF0342 family
KQ224_RS02510	COG0287	Prephenate dehydrogenase
KQ224_RS02515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KQ224_RS02520	COG0710	3-dehydroquinate dehydratase activity
KQ224_RS02525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KQ224_RS02530	COG1368	sulfuric ester hydrolase activity
KQ224_RS02540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KQ224_RS02550	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KQ224_RS02570	COG0704	Plays a role in the regulation of phosphate uptake
KQ224_RS02575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQ224_RS02580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQ224_RS02585	COG0581	inorganic phosphate transmembrane transporter activity
KQ224_RS02590	COG0573	inorganic phosphate transmembrane transporter activity
KQ224_RS02605	COG0483	inositol monophosphate 1-phosphatase activity
KQ224_RS02610	COG4476	Belongs to the UPF0223 family
KQ224_RS02615	COG1393	Belongs to the ArsC family
KQ224_RS02620	COG0196	riboflavin kinase activity
KQ224_RS02625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KQ224_RS02655	COG0561	phosphatase activity
KQ224_RS02660	COG2195	Cleaves the N-terminal amino acid of tripeptides
KQ224_RS02675	COG3759	membrane
KQ224_RS02680	COG1846	Transcriptional regulator
KQ224_RS02695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KQ224_RS02700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ224_RS02705	COG1126	abc transporter atp-binding protein
KQ224_RS02710	COG0765	amino acid transport
KQ224_RS02715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQ224_RS02725	COG2755	lipolytic protein G-D-S-L family
KQ224_RS02725	COG0657	acetylesterase activity
KQ224_RS02730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ224_RS02735	COG0469	pyruvate kinase activity
KQ224_RS02740	COG0205	6-phosphofructokinase activity
KQ224_RS02750	COG2188	Transcriptional regulator
KQ224_RS02755	COG1131	(ABC) transporter
KQ224_RS02765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KQ224_RS02805	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KQ224_RS02810	COG1982	Orn Lys Arg decarboxylase major
KQ224_RS02815	COG2151	metal-sulfur cluster biosynthetic enzyme
KQ224_RS02820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KQ224_RS02825	COG0358	DNA primase activity
KQ224_RS02830	COG1970	mechanosensitive ion channel activity
KQ224_RS02835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ224_RS02840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KQ224_RS02850	COG0647	UMP catabolic process
KQ224_RS02855	COG1051	belongs to the nudix hydrolase family
KQ224_RS02865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KQ224_RS02875	COG0058	SHG alpha-glucan phosphorylase activity
KQ224_RS02880	COG0813	purine-nucleoside phosphorylase activity
KQ224_RS02885	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KQ224_RS02890	COG1393	Belongs to the ArsC family
KQ224_RS02895	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KQ224_RS02900	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KQ224_RS02920	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KQ224_RS02925	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KQ224_RS02935	COG1704	LemA family
KQ224_RS02945	COG1573	uracil-dna glycosylase
KQ224_RS02960	COG0673	inositol 2-dehydrogenase activity
KQ224_RS02980	COG2207	Transcriptional regulator
KQ224_RS02990	COG0390	transport system, permease component
KQ224_RS02995	COG4619	ABC transporter
KQ224_RS03000	COG0662	Cupin 2, conserved barrel domain protein
KQ224_RS03010	COG2226	methyltransferase
KQ224_RS03015	COG0488	(ABC) transporter
KQ224_RS03020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ224_RS03030	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KQ224_RS03035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KQ224_RS03040	COG3442	glutamine amidotransferase
KQ224_RS03055	COG0107	imidazoleglycerol-phosphate synthase activity
KQ224_RS03060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KQ224_RS03065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KQ224_RS03075	COG0560	Phosphoserine phosphatase
KQ224_RS03080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KQ224_RS03085	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KQ224_RS03090	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KQ224_RS03105	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KQ224_RS03110	COG0187	DNA topoisomerase II activity
KQ224_RS03120	COG0772	Belongs to the SEDS family
KQ224_RS03135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KQ224_RS03140	COG0716	FMN binding
KQ224_RS03150	COG1605	Chorismate mutase
KQ224_RS03150	COG0077	Prephenate dehydratase
KQ224_RS03155	COG0038	chloride channel
KQ224_RS03165	COG1562	ergosterol biosynthetic process
KQ224_RS03190	COG1132	(ABC) transporter
KQ224_RS03195	COG1132	(ABC) transporter
KQ224_RS03200	COG0335	large ribosomal subunit rRNA binding
KQ224_RS03205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KQ224_RS03210	COG1466	dna polymerase III delta subunit
KQ224_RS03215	COG0658	competence protein
KQ224_RS03215	COG2333	competence protein COMEC
KQ224_RS03220	COG1596	polysaccharide export
KQ224_RS03220	COG1555	photosystem II stabilization
KQ224_RS03225	COG0204	Acyl-transferase
KQ224_RS03230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KQ224_RS03250	COG0513	Belongs to the DEAD box helicase family
KQ224_RS03265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KQ224_RS03285	COG1181	Belongs to the D-alanine--D-alanine ligase family
KQ224_RS03290	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KQ224_RS03295	COG0768	penicillin binding
KQ224_RS03300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KQ224_RS03310	COG0745	RESPONSE REGULATOR receiver
KQ224_RS03315	COG1126	abc transporter atp-binding protein
KQ224_RS03320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ224_RS03325	COG0765	amino acid transport
KQ224_RS03330	COG0765	amino acid transport
KQ224_RS03335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KQ224_RS03350	COG0438	transferase activity, transferring glycosyl groups
KQ224_RS03355	COG0438	transferase activity, transferring glycosyl groups
KQ224_RS03360	COG1609	Transcriptional regulator
KQ224_RS03375	COG0456	acetyltransferase
KQ224_RS03380	COG0343	queuine tRNA-ribosyltransferase activity
KQ224_RS03395	COG3022	response to hydroperoxide
KQ224_RS03400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ224_RS03405	COG1307	EDD domain protein, DegV family
KQ224_RS03415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KQ224_RS03420	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KQ224_RS03425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KQ224_RS03430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ224_RS03430	COG1199	ATP-dependent helicase activity
KQ224_RS03445	COG2177	Part of the ABC transporter FtsEX involved in
KQ224_RS03450	COG2884	Cell division ATP-binding protein ftsE
KQ224_RS03460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KQ224_RS03495	COG1078	dGTPase activity
KQ224_RS03505	COG0149	triose-phosphate isomerase activity
KQ224_RS03510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KQ224_RS03525	COG1191	sigma factor activity
KQ224_RS03530	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KQ224_RS03535	COG0772	Belongs to the SEDS family
KQ224_RS03555	COG3859	Proton-coupled thiamine transporter YuaJ
KQ224_RS03565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KQ224_RS03575	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KQ224_RS03595	COG0577	efflux transmembrane transporter activity
KQ224_RS03600	COG1136	(ABC) transporter
KQ224_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ224_RS03610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ224_RS03615	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KQ224_RS03620	COG1268	BioY protein
KQ224_RS03625	COG4443	Transcriptional Coactivator p15 (PC4)
KQ224_RS03635	COG0826	peptidase U32
KQ224_RS03650	COG0789	Transcriptional regulator
KQ224_RS03660	COG1227	inorganic diphosphatase activity
KQ224_RS03670	COG1733	regulation of RNA biosynthetic process
KQ224_RS03675	COG2514	catechol 2,3-dioxygenase activity
KQ224_RS03680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KQ224_RS03690	COG1253	flavin adenine dinucleotide binding
KQ224_RS03695	COG1119	ATPase activity
KQ224_RS03700	COG0025	NhaP-type Na H and K H
KQ224_RS03705	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KQ224_RS03725	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KQ224_RS03730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KQ224_RS03745	COG4470	Protein conserved in bacteria
KQ224_RS03750	COG3480	Lon protease (S16) C-terminal proteolytic domain
KQ224_RS03755	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KQ224_RS03760	COG0742	ribosomal rna small subunit methyltransferase
KQ224_RS03770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KQ224_RS03775	COG4483	Protein conserved in bacteria
KQ224_RS03780	COG2197	response regulator
KQ224_RS03785	COG4585	Histidine kinase
KQ224_RS03790	COG0842	Transport permease protein
KQ224_RS03795	COG1131	(ABC) transporter
KQ224_RS03810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KQ224_RS03830	COG0671	phosphoesterase, PA-phosphatase related
KQ224_RS03835	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KQ224_RS03845	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KQ224_RS03850	COG1187	pseudouridine synthase activity
KQ224_RS03855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KQ224_RS03860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KQ224_RS03865	COG0582	viral genome integration into host DNA
KQ224_RS03885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ224_RS03890	COG3763	UPF0154 protein
KQ224_RS03900	COG3579	cysteine-type endopeptidase activity
KQ224_RS03915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ224_RS03920	COG1254	Belongs to the acylphosphatase family
KQ224_RS03925	COG0706	membrane insertase activity
KQ224_RS03930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KQ224_RS03935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KQ224_RS03945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KQ224_RS03955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KQ224_RS03970	COG1160	GTP binding
KQ224_RS03980	COG1484	DNA-dependent DNA replication
KQ224_RS03990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KQ224_RS03995	COG0628	permease
KQ224_RS04000	COG0745	RESPONSE REGULATOR receiver
KQ224_RS04005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KQ224_RS04015	COG0492	ferredoxin-NADP+ reductase activity
KQ224_RS04025	COG0513	Belongs to the DEAD box helicase family
KQ224_RS04035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KQ224_RS04040	COG0768	penicillin binding
KQ224_RS04050	COG0275	rRNA processing
KQ224_RS04100	COG4939	FMN-binding domain protein
KQ224_RS04105	COG0142	geranyltranstransferase activity
KQ224_RS04110	COG1252	NADH dehydrogenase
KQ224_RS04120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KQ224_RS04125	COG0569	domain protein
KQ224_RS04140	COG0751	glycine-tRNA ligase activity
KQ224_RS04165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ224_RS04170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KQ224_RS04175	COG1464	Belongs to the NlpA lipoprotein family
KQ224_RS04180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KQ224_RS04185	COG4608	Belongs to the ABC transporter superfamily
KQ224_RS04190	COG0444	Belongs to the ABC transporter superfamily
KQ224_RS04195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ224_RS04210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KQ224_RS04215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KQ224_RS04220	COG2252	PERMEase
KQ224_RS04225	COG0561	phosphatase activity
KQ224_RS04235	COG3715	PTS system
KQ224_RS04240	COG3716	PTS system mannose fructose sorbose family IID component
KQ224_RS04275	COG0439	Biotin carboxylase
KQ224_RS04295	COG1028	Short-chain dehydrogenase reductase Sdr
KQ224_RS04300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KQ224_RS04315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KQ224_RS04325	COG1024	Enoyl-CoA hydratase
KQ224_RS04330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQ224_RS04335	COG0527	aspartate kinase activity
KQ224_RS04340	COG3684	Belongs to the aldolase LacD family
KQ224_RS04350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KQ224_RS04355	COG0736	holo-[acyl-carrier-protein] synthase activity
KQ224_RS04360	COG0653	protein targeting
KQ224_RS04365	COG1940	carbohydrate kinase activity
KQ224_RS04370	COG2190	(PTS) system
KQ224_RS04370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KQ224_RS04370	COG1263	PTS System
KQ224_RS04375	COG1621	beta-fructofuranosidase activity
KQ224_RS04380	COG1609	Transcriptional regulator
KQ224_RS04385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KQ224_RS04400	COG0006	proline dipeptidase activity
KQ224_RS04405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KQ224_RS04420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KQ224_RS04425	COG0629	single-stranded DNA binding
KQ224_RS04435	COG0095	Lipoate-protein ligase
KQ224_RS04455	COG0159	tryptophan synthase activity
KQ224_RS04460	COG0133	tryptophan synthase activity
KQ224_RS04465	COG0135	phosphoribosylanthranilate isomerase activity
KQ224_RS04470	COG0134	indole-3-glycerol-phosphate synthase activity
KQ224_RS04480	COG0512	Glutamine amidotransferase of anthranilate synthase
KQ224_RS04485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KQ224_RS04495	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ224_RS04500	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ224_RS04500	COG0022	dehydrogenase e1 component
KQ224_RS04505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KQ224_RS04510	COG2860	membrane
KQ224_RS04535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KQ224_RS04540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KQ224_RS04550	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KQ224_RS04555	COG0195	Participates in both transcription termination and antitermination
KQ224_RS04605	COG2801	Transposase and inactivated derivatives
KQ224_RS04635	COG1705	Flagellar rod assembly protein muramidase FlgJ
KQ224_RS04635	COG3942	CHAP domain
KQ224_RS04645	COG0488	(ABC) transporter
KQ224_RS04670	COG0010	Belongs to the arginase family
KQ224_RS04680	COG0191	fructose-bisphosphate aldolase activity
KQ224_RS04690	COG0129	dihydroxy-acid dehydratase activity
KQ224_RS04700	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KQ224_RS04720	COG2188	Transcriptional regulator
KQ224_RS04730	COG3557	Belongs to the UPF0374 family
KQ224_RS04740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KQ224_RS04825	COG1040	competence protein
KQ224_RS04830	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KQ224_RS04835	COG1739	Uncharacterized protein family UPF0029
KQ224_RS04845	COG5632	N-Acetylmuramoyl-L-alanine amidase
KQ224_RS04845	COG3409	Peptidoglycan-binding domain 1 protein
KQ224_RS04945	COG2369	cell adhesion
KQ224_RS05040	COG0419	ATPase involved in DNA repair
KQ224_RS05090	COG4974	Belongs to the 'phage' integrase family
KQ224_RS05100	COG1185	polyribonucleotide nucleotidyltransferase activity
KQ224_RS05115	COG4585	Histidine kinase
KQ224_RS05125	COG2815	serine threonine protein kinase
KQ224_RS05125	COG0515	serine threonine protein kinase
KQ224_RS05130	COG0631	protein serine/threonine phosphatase activity
KQ224_RS05135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KQ224_RS05135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KQ224_RS05140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KQ224_RS05145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KQ224_RS05150	COG1758	RNA polymerase activity
KQ224_RS05160	COG1418	mRNA catabolic process
KQ224_RS05165	COG1854	S-ribosylhomocysteine lyase activity
KQ224_RS05175	COG0116	Belongs to the methyltransferase superfamily
KQ224_RS05185	COG3599	regulation of cell shape
KQ224_RS05190	COG4474	Belongs to the UPF0398 family
KQ224_RS05195	COG3331	DNA recombination
KQ224_RS05200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQ224_RS05205	COG0357	Ribosomal RNA small subunit methyltransferase G
KQ224_RS05220	COG1122	ATPase activity
KQ224_RS05225	COG1054	Belongs to the UPF0176 family
KQ224_RS05230	COG4720	Psort location CytoplasmicMembrane, score
KQ224_RS05240	COG0217	transcriptional regulatory protein
KQ224_RS05245	COG2190	(PTS) system
KQ224_RS05245	COG1263	PTS System
KQ224_RS05245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KQ224_RS05260	COG0058	SHG alpha-glucan phosphorylase activity
KQ224_RS05265	COG1640	4-alpha-glucanotransferase
KQ224_RS05275	COG0242	peptide deformylase activity
KQ224_RS05295	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KQ224_RS05300	COG0789	Transcriptional regulator
KQ224_RS05320	COG2226	methyltransferase
KQ224_RS05325	COG0799	negative regulation of ribosome biogenesis
KQ224_RS05330	COG1335	isochorismatase
KQ224_RS05335	COG1713	HD superfamily hydrolase involved in NAD metabolism
KQ224_RS05340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KQ224_RS05345	COG1534	Rna-binding protein
KQ224_RS05355	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KQ224_RS05375	COG3142	Participates in the control of copper homeostasis
KQ224_RS05385	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KQ224_RS05390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KQ224_RS05395	COG1609	Transcriptional regulator
KQ224_RS05400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ224_RS05405	COG0154	amidase activity
KQ224_RS05410	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ224_RS05415	COG1335	isochorismatase
KQ224_RS05420	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KQ224_RS05425	COG0436	Aminotransferase
KQ224_RS05430	COG0589	response to stress
KQ224_RS05450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KQ224_RS05495	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KQ224_RS05515	COG1045	serine acetyltransferase
KQ224_RS05520	COG1185	polyribonucleotide nucleotidyltransferase activity
KQ224_RS05530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KQ224_RS05570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KQ224_RS05580	COG1187	pseudouridine synthase activity
KQ224_RS05595	COG0242	peptide deformylase activity
KQ224_RS05605	COG0066	3-isopropylmalate dehydratase activity
KQ224_RS05610	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KQ224_RS05615	COG0473	3-isopropylmalate dehydrogenase activity
KQ224_RS05630	COG2309	aminopeptidase activity
KQ224_RS05640	COG2176	DNA-directed DNA polymerase activity
KQ224_RS05650	COG0442	prolyl-tRNA aminoacylation
KQ224_RS05660	COG4589	Belongs to the CDS family
KQ224_RS05665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KQ224_RS05670	COG1862	Preprotein translocase
KQ224_RS05680	COG1181	Belongs to the D-alanine--D-alanine ligase family
KQ224_RS05680	COG2918	glutathione biosynthetic process
KQ224_RS05685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KQ224_RS05690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ224_RS05705	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KQ224_RS05710	COG0542	response to heat
KQ224_RS05715	COG4463	regulation of RNA biosynthetic process
KQ224_RS05725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KQ224_RS05755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KQ224_RS05760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQ224_RS05765	COG0492	ferredoxin-NADP+ reductase activity
KQ224_RS05770	COG0564	pseudouridine synthase activity
KQ224_RS05790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KQ224_RS05800	COG3481	metal-dependent phosphohydrolase, HD sub domain
KQ224_RS05810	COG1564	THIamine pyrophosphokinase
KQ224_RS05820	COG1162	GTPase activity
KQ224_RS05835	COG1335	isochorismatase
KQ224_RS05870	COG0084	hydrolase, TatD family'
KQ224_RS05875	COG1597	lipid kinase activity
KQ224_RS05885	COG1847	R3H domain protein
KQ224_RS05895	COG0594	ribonuclease P activity
KQ224_RS05900	COG0165	Argininosuccinate lyase
KQ224_RS05905	COG0137	argininosuccinate synthase activity
KQ224_RS05915	COG1827	regulation of RNA biosynthetic process
KQ224_RS05990	COG0756	dUTP diphosphatase activity
KQ224_RS05995	COG2832	Protein of unknown function (DUF454)
KQ224_RS06005	COG1053	succinate dehydrogenase
KQ224_RS06005	COG0431	NADPH-dependent FMN reductase
KQ224_RS06005	COG3976	FMN-binding domain protein
KQ224_RS06015	COG1132	(ABC) transporter
KQ224_RS06020	COG1132	(ABC) transporter
KQ224_RS06030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KQ224_RS06035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KQ224_RS06045	COG0705	Rhomboid family
KQ224_RS06050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KQ224_RS06055	COG1473	amidohydrolase
KQ224_RS06060	COG2171	N-acyltransferase activity
KQ224_RS06065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KQ224_RS06070	COG0166	Belongs to the GPI family
KQ224_RS06090	COG1914	H( )-stimulated, divalent metal cation uptake system
KQ224_RS06095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KQ224_RS06100	COG1523	belongs to the glycosyl hydrolase 13 family
KQ224_RS06105	COG1609	Transcriptional regulator
KQ224_RS06110	COG3942	CHAP domain
KQ224_RS06130	COG4667	esterase of the alpha-beta hydrolase superfamily
KQ224_RS06135	COG3590	peptidase
KQ224_RS06165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ224_RS06170	COG2274	protein secretion by the type I secretion system
KQ224_RS06215	COG3290	protein histidine kinase activity
KQ224_RS06225	COG1490	D-aminoacyl-tRNA deacylase activity
KQ224_RS06245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ224_RS06270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KQ224_RS06295	COG3906	Belongs to the UPF0473 family
KQ224_RS06300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KQ224_RS06305	COG4472	Bacterial protein of unknown function (DUF965)
KQ224_RS06310	COG1393	Belongs to the ArsC family
KQ224_RS06325	COG0519	Catalyzes the synthesis of GMP from XMP
KQ224_RS06330	COG0632	four-way junction helicase activity
KQ224_RS06335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KQ224_RS06345	COG0285	dihydrofolate synthase activity
KQ224_RS06365	COG2255	four-way junction helicase activity
KQ224_RS06370	COG0765	amino acid transport
KQ224_RS06375	COG4215	(ABC) transporter
KQ224_RS06380	COG1126	abc transporter atp-binding protein
KQ224_RS06385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ224_RS06405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ224_RS06410	COG2274	protein secretion by the type I secretion system
KQ224_RS06455	COG1131	(ABC) transporter
KQ224_RS06485	COG1122	ATPase activity
KQ224_RS06505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KQ224_RS06515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KQ224_RS06520	COG0151	Belongs to the GarS family
KQ224_RS06525	COG0138	bifunctional purine biosynthesis protein purh
KQ224_RS06535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KQ224_RS06550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KQ224_RS06560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KQ224_RS06565	COG0416	fatty acid biosynthetic process
KQ224_RS06570	COG1381	Involved in DNA repair and RecF pathway recombination
KQ224_RS06575	COG0436	Aminotransferase
KQ224_RS06580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ224_RS06595	COG1792	Involved in formation and maintenance of cell shape
KQ224_RS06700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ224_RS06705	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KQ224_RS06710	COG0037	tRNA processing
KQ224_RS06725	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KQ224_RS06730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KQ224_RS06735	COG0193	aminoacyl-tRNA hydrolase activity
KQ224_RS06740	COG0012	GTP binding
KQ224_RS06760	COG0592	DNA-directed DNA polymerase activity
KQ224_RS06765	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KQ224_RS06775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ224_RS06780	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KQ224_RS06810	COG0488	(ABC) transporter
KQ224_RS06815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KQ224_RS06825	COG0516	GMP reductase activity
KQ224_RS06825	COG0517	IMP dehydrogenase activity
KQ224_RS06835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KQ224_RS06845	COG0612	Peptidase, M16
KQ224_RS06850	COG0612	Peptidase, M16
KQ224_RS06855	COG1426	Protein conserved in bacteria
KQ224_RS06860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KQ224_RS06865	COG1122	ATPase activity
KQ224_RS06870	COG1122	ATPase activity
KQ224_RS06895	COG1760	l-serine dehydratase
KQ224_RS06900	COG1760	l-serine dehydratase
KQ224_RS06905	COG0482	sulfurtransferase activity
KQ224_RS06920	COG0494	nUDIX hydrolase
KQ224_RS06925	COG0445	tRNA wobble uridine modification
KQ224_RS06935	COG0359	binds to the 23S rRNA
KQ224_RS06940	COG0305	Participates in initiation and elongation during chromosome replication
KQ224_RS06950	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KQ224_RS06990	COG1216	Glycosyl transferase, family 2
KQ224_RS06995	COG4989	oxidoreductase activity
KQ224_RS07005	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KQ224_RS07010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KQ224_RS07015	COG1780	Probably involved in ribonucleotide reductase function
KQ224_RS07020	COG1523	belongs to the glycosyl hydrolase 13 family
KQ224_RS07025	COG1609	Transcriptional regulator
KQ224_RS07030	COG5521	maltodextrose utilization protein MalA
KQ224_RS07035	COG3833	ABC-type maltose transport systems, permease component
KQ224_RS07040	COG1175	transmembrane transport
KQ224_RS07045	COG2182	Extracellular solute-binding protein
KQ224_RS07050	COG1640	4-alpha-glucanotransferase
KQ224_RS07070	COG0018	arginyl-trna synthetase
KQ224_RS07075	COG1438	arginine binding
KQ224_RS07105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ224_RS07115	COG1126	abc transporter atp-binding protein
KQ224_RS07120	COG1328	CTP reductase activity
KQ224_RS07125	COG0737	Belongs to the 5'-nucleotidase family
KQ224_RS07150	COG0051	transcription antitermination factor activity, RNA binding
KQ224_RS07155	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KQ224_RS07160	COG0088	Forms part of the polypeptide exit tunnel
KQ224_RS07165	COG0089	rRNA binding
KQ224_RS07170	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KQ224_RS07175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KQ224_RS07180	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KQ224_RS07185	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KQ224_RS07190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KQ224_RS07195	COG0255	Belongs to the universal ribosomal protein uL29 family
KQ224_RS07200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KQ224_RS07205	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KQ224_RS07210	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KQ224_RS07215	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KQ224_RS07220	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KQ224_RS07225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KQ224_RS07230	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KQ224_RS07235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KQ224_RS07240	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KQ224_RS07245	COG1841	ribosomal large subunit assembly
KQ224_RS07255	COG0201	protein transport
KQ224_RS07260	COG0563	adenylate kinase activity
KQ224_RS07265	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KQ224_RS07270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KQ224_RS07275	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KQ224_RS07285	COG0202	RNA polymerase activity
KQ224_RS07370	COG0582	viral genome integration into host DNA
KQ224_RS07380	COG1705	Flagellar rod assembly protein muramidase FlgJ
KQ224_RS07380	COG3942	CHAP domain
KQ224_RS07395	COG0433	COG0433 Predicted ATPase
KQ224_RS07435	COG1674	ftsk spoiiie
KQ224_RS07455	COG1396	sequence-specific DNA binding
KQ224_RS07485	COG2801	Transposase and inactivated derivatives
KQ224_RS07490	COG4974	Belongs to the 'phage' integrase family
KQ224_RS07520	COG2801	Transposase and inactivated derivatives
KQ224_RS07545	COG1121	(ABC) transporter
KQ224_RS07550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KQ224_RS07555	COG3443	Belongs to the bacterial solute-binding protein 9 family
KQ224_RS07555	COG0803	Belongs to the bacterial solute-binding protein 9 family
KQ224_RS07560	COG3682	Transcriptional regulator
KQ224_RS07570	COG0515	serine threonine protein kinase
KQ224_RS07585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQ224_RS07590	COG0085	RNA polymerase activity
KQ224_RS07595	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KQ224_RS07605	COG1619	proteins homologs of microcin C7 resistance protein MccF
KQ224_RS07610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KQ224_RS07615	COG1459	type II secretion system
KQ224_RS07620	COG4537	Required for transformation and DNA binding
KQ224_RS07650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KQ224_RS07665	COG1363	Peptidase, m42
KQ224_RS07675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KQ224_RS07685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ224_RS07690	COG0596	Alpha beta hydrolase
KQ224_RS07705	COG0459	protein refolding
KQ224_RS07715	COG0049	tRNA binding
KQ224_RS07720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KQ224_RS07730	COG1979	alcohol dehydrogenase
KQ224_RS07735	COG0656	L-ascorbic acid biosynthetic process
KQ224_RS07740	COG0126	phosphoglycerate kinase activity
KQ224_RS07750	COG0789	Transcriptional regulator
KQ224_RS07755	COG0174	glutamine synthetase
KQ224_RS07765	COG5503	Protein of unknown function (DUF1447)
KQ224_RS07770	COG1214	PFAM Peptidase M22, glycoprotease
KQ224_RS07780	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KQ224_RS07785	COG1131	(ABC) transporter
KQ224_RS07805	COG2855	membrane
KQ224_RS07825	COG2081	HI0933 family
KQ224_RS07845	COG1388	LysM domain
KQ224_RS07850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KQ224_RS07860	COG2217	Heavy metal translocating P-type atpase
KQ224_RS07865	COG2217	Heavy metal translocating P-type atpase
KQ224_RS07885	COG0739	heme binding
KQ224_RS07885	COG0741	lytic transglycosylase activity
KQ224_RS07885	COG1196	nuclear chromosome segregation
KQ224_RS07890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KQ224_RS07905	COG2205	protein histidine kinase activity
KQ224_RS07925	COG2132	Multicopper oxidase
KQ224_RS07955	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KQ224_RS08005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ224_RS08015	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KQ224_RS08045	COG1882	Formate acetyltransferase
KQ224_RS08055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQ224_RS08060	COG0681	Belongs to the peptidase S26 family
KQ224_RS08075	COG1785	Belongs to the alkaline phosphatase family
KQ224_RS08085	COG5646	InterPro IPR014922
KQ224_RS08090	COG0366	Alpha amylase catalytic
KQ224_RS08100	COG2188	Transcriptional regulator
KQ224_RS08115	COG1193	negative regulation of DNA recombination
KQ224_RS08120	COG3118	belongs to the thioredoxin family
KQ224_RS08130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KQ224_RS08130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KQ224_RS08140	COG0668	transmembrane transport
KQ224_RS08150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ224_RS08155	COG0167	dihydroorotate dehydrogenase activity
KQ224_RS08195	COG0561	phosphatase activity
KQ224_RS08200	COG0561	phosphatase activity
KQ224_RS08215	COG4555	ABC transporter
KQ224_RS08220	COG1309	transcriptional regulator
KQ224_RS08225	COG1511	domain protein
KQ224_RS08230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KQ224_RS08255	COG1346	cytolysis
KQ224_RS08260	COG2116	formate transmembrane transporter activity
KQ224_RS08265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KQ224_RS08270	COG0433	COG0433 Predicted ATPase
KQ224_RS08275	COG0494	nUDIX hydrolase
KQ224_RS08280	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ224_RS08285	COG3448	diguanylate cyclase activity
KQ224_RS08285	COG4175	Glycine betaine
KQ224_RS08300	COG0701	Predicted permease
KQ224_RS08340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KQ224_RS08345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KQ224_RS08365	COG0124	histidyl-tRNA synthetase
KQ224_RS08370	COG1454	alcohol dehydrogenase
KQ224_RS08370	COG1012	belongs to the aldehyde dehydrogenase family
KQ224_RS08380	COG1461	Dihydroxyacetone kinase
KQ224_RS08385	COG0802	atpase or kinase
KQ224_RS08390	COG1247	-acetyltransferase
KQ224_RS08395	COG1316	TRANSCRIPTIONal
KQ224_RS08405	COG0537	adenosine 5'-monophosphoramidase activity
KQ224_RS08410	COG1131	(ABC) transporter
KQ224_RS08415	COG4473	ABC transporter
KQ224_RS08425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KQ224_RS08430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KQ224_RS08440	COG3842	ATPase activity
KQ224_RS08470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ224_RS08495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KQ224_RS08545	COG1121	(ABC) transporter
KQ224_RS08590	COG1396	sequence-specific DNA binding
KQ224_RS08680	COG2207	Transcriptional regulator
KQ224_RS08680	COG0662	Cupin 2, conserved barrel domain protein
KQ224_RS08685	COG0488	(ABC) transporter
KQ224_RS08715	COG2151	metal-sulfur cluster biosynthetic enzyme
KQ224_RS08725	COG0129	dihydroxy-acid dehydratase activity
KQ224_RS08745	COG0028	Belongs to the TPP enzyme family
KQ224_RS08750	COG0440	acetolactate synthase activity
KQ224_RS08755	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KQ224_RS08760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQ224_RS08775	COG1126	abc transporter atp-binding protein
KQ224_RS08780	COG0765	amino acid transport
KQ224_RS08785	COG1968	undecaprenyl-diphosphatase activity
KQ224_RS08790	COG4862	establishment of competence for transformation
KQ224_RS08795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KQ224_RS08805	COG0719	Fe-S assembly protein
KQ224_RS08810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQ224_RS08825	COG1686	Belongs to the peptidase S11 family
KQ224_RS08840	COG4608	Belongs to the ABC transporter superfamily
KQ224_RS08845	COG0601	transmembrane transport
KQ224_RS08850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ224_RS08860	COG0534	Mate efflux family protein
KQ224_RS08865	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KQ224_RS08880	COG1304	FMN binding
KQ224_RS08885	COG3830	Belongs to the UPF0237 family
KQ224_RS08890	COG2848	UPF0210 protein
KQ224_RS08895	COG0588	phosphoglycerate mutase activity
KQ224_RS08910	COG1396	sequence-specific DNA binding
KQ224_RS08925	COG1420	regulation of RNA biosynthetic process
KQ224_RS08930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KQ224_RS08935	COG0443	Heat shock 70 kDa protein
KQ224_RS08940	COG0484	heat shock protein binding
KQ224_RS08950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ224_RS08955	COG0765	amino acid transport
KQ224_RS08960	COG2217	Heavy metal translocating P-type atpase
KQ224_RS08980	COG0351	phosphomethylpyrimidine kinase
KQ224_RS08990	COG4475	Protein of unknown function (DUF436)
KQ224_RS09005	COG0544	peptidyl-prolyl cis-trans isomerase activity
KQ224_RS09020	COG3343	RNA polymerase activity
KQ224_RS09025	COG0504	CTP synthase activity
KQ224_RS09040	COG0346	lactoylglutathione lyase activity
KQ224_RS09065	COG0494	nUDIX hydrolase
KQ224_RS09080	COG1217	gtp-binding protein TYPA
KQ224_RS09105	COG0366	Alpha amylase catalytic
KQ224_RS09105	COG1874	Beta-galactosidase
KQ224_RS09115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KQ224_RS09135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KQ224_RS09140	COG1799	cell septum assembly
KQ224_RS09150	COG2302	S4 RNA-binding domain
KQ224_RS09155	COG3599	regulation of cell shape
KQ224_RS09175	COG0494	nUDIX hydrolase
KQ224_RS09180	COG0542	response to heat
KQ224_RS09185	COG4703	Protein of unknown function (DUF1797)
KQ224_RS09190	COG0765	amino acid transport
KQ224_RS09200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KQ224_RS09205	COG2321	neutral zinc metallopeptidase
KQ224_RS09210	COG1570	exodeoxyribonuclease VII activity
KQ224_RS09215	COG1722	exodeoxyribonuclease VII activity
KQ224_RS09225	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KQ224_RS09230	COG1438	arginine binding
KQ224_RS09235	COG0497	DNA recombination
KQ224_RS09240	COG1418	mRNA catabolic process
KQ224_RS09250	COG1307	EDD domain protein, DegV family
KQ224_RS09255	COG2755	lipolytic protein G-D-S-L family
KQ224_RS09265	COG0776	regulation of translation
KQ224_RS09270	COG0582	viral genome integration into host DNA
KQ224_RS09300	COG3425	synthase
KQ224_RS09305	COG0183	Belongs to the thiolase family
KQ224_RS09320	COG0726	polysaccharide deacetylase
KQ224_RS09330	COG0673	inositol 2-dehydrogenase activity
KQ224_RS09340	COG1695	Transcriptional regulator
KQ224_RS09350	COG1956	GAF domain-containing protein
KQ224_RS09355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KQ224_RS09370	COG1363	Peptidase, m42
KQ224_RS09380	COG2131	deaminase
KQ224_RS09385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KQ224_RS09390	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ224_RS09395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KQ224_RS09405	COG0024	Methionine aminopeptidase
KQ224_RS09415	COG2246	polysaccharide biosynthetic process
KQ224_RS09420	COG4708	membrane
KQ224_RS09425	COG1428	Deoxynucleoside kinase
KQ224_RS09430	COG2183	response to ionizing radiation
KQ224_RS09435	COG3091	SprT-like family
KQ224_RS09450	COG1482	cell wall glycoprotein biosynthetic process
KQ224_RS09455	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KQ224_RS09460	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KQ224_RS09475	COG0436	Aminotransferase
KQ224_RS09490	COG2205	protein histidine kinase activity
KQ224_RS09495	COG1136	(ABC) transporter
KQ224_RS09505	COG2801	Transposase and inactivated derivatives
KQ224_RS09510	COG0577	efflux transmembrane transporter activity
KQ224_RS09515	COG0004	ammonium transporteR
KQ224_RS09520	COG0347	Belongs to the P(II) protein family
KQ224_RS09550	COG1028	Short-chain dehydrogenase reductase Sdr
KQ224_RS09555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KQ224_RS09565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KQ224_RS09570	COG0494	nUDIX hydrolase
KQ224_RS09580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KQ224_RS09595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KQ224_RS09615	COG0346	lactoylglutathione lyase activity
KQ224_RS09620	COG4166	transmembrane transport
KQ224_RS09625	COG0601	transmembrane transport
KQ224_RS09630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ224_RS09635	COG0444	Belongs to the ABC transporter superfamily
KQ224_RS09640	COG4608	Belongs to the ABC transporter superfamily
KQ224_RS09665	COG0625	glutathione transferase activity
KQ224_RS09670	COG2244	polysaccharide biosynthetic process
KQ224_RS09675	COG0528	UMP kinase activity
KQ224_RS09680	COG0233	cytoplasmic translational termination
KQ224_RS09685	COG2996	Protein conserved in bacteria
KQ224_RS09700	COG4479	Belongs to the UPF0346 family
KQ224_RS09705	COG1702	phosphate starvation-inducible protein PhoH
KQ224_RS09730	COG1132	(ABC) transporter
KQ224_RS09735	COG1132	(ABC) transporter
KQ224_RS09740	COG2261	transglycosylase associated protein
KQ224_RS09745	COG2261	transglycosylase associated protein
KQ224_RS09750	COG2261	transglycosylase associated protein
KQ224_RS09755	COG2261	transglycosylase associated protein
KQ224_RS09785	COG0490	domain, Protein
KQ224_RS09805	COG0596	Alpha beta hydrolase
KQ224_RS09815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KQ224_RS09820	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KQ224_RS09830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KQ224_RS09840	COG2814	Major facilitator Superfamily
KQ224_RS09845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KQ224_RS09855	COG0557	exoribonuclease II activity
KQ224_RS09860	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KQ224_RS09885	COG1129	ABC transporter
KQ224_RS09900	COG1063	alcohol dehydrogenase
KQ224_RS09910	COG2217	Heavy metal translocating P-type atpase
KQ224_RS09915	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KQ224_RS09930	COG1316	TRANSCRIPTIONal
KQ224_RS09960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KQ224_RS09970	COG0438	transferase activity, transferring glycosyl groups
KQ224_RS10005	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KQ224_RS10010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ224_RS10055	COG1396	sequence-specific DNA binding
KQ224_RS10060	COG0542	response to heat
KQ224_RS10070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KQ224_RS10070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KQ224_RS10080	COG1832	CoA-binding protein
KQ224_RS10100	COG0436	Aminotransferase
KQ224_RS10135	COG0534	Mate efflux family protein
KQ224_RS10140	COG0251	oxidation-reduction process
KQ224_RS10145	COG1660	Displays ATPase and GTPase activities
KQ224_RS10150	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KQ224_RS10155	COG1481	regulation of sporulation
KQ224_RS10165	COG0454	-acetyltransferase
KQ224_RS10170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KQ224_RS10180	COG2814	Major facilitator Superfamily
KQ224_RS10190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KQ224_RS10195	COG0363	glucosamine-6-phosphate deaminase activity
KQ224_RS10200	COG0435	Glutathione S-transferase
KQ224_RS10210	COG0386	Belongs to the glutathione peroxidase family
KQ224_RS10215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ224_RS10220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ224_RS10225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KQ224_RS10230	COG1120	ATPase activity
KQ224_RS10235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KQ224_RS10240	COG0626	cystathionine gamma-synthase activity
KQ224_RS10245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KQ224_RS10250	COG2207	Transcriptional regulator
KQ224_RS10260	COG1653	transport
KQ224_RS10265	COG1175	transmembrane transport
KQ224_RS10270	COG0395	ABC-type sugar transport system, permease component
KQ224_RS10280	COG0366	Alpha amylase catalytic
KQ224_RS10285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KQ224_RS10300	COG0683	leucine binding
KQ224_RS10305	COG0559	Belongs to the binding-protein-dependent transport system permease family
KQ224_RS10345	COG1011	Hydrolase
KQ224_RS10355	COG2706	6-phosphogluconolactonase activity
KQ224_RS10360	COG0628	permease
KQ224_RS10370	COG3527	Alpha-acetolactate decarboxylase
KQ224_RS10380	COG0573	inorganic phosphate transmembrane transporter activity
KQ224_RS10385	COG0581	inorganic phosphate transmembrane transporter activity
KQ224_RS10390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQ224_RS10400	COG0745	RESPONSE REGULATOR receiver
KQ224_RS10405	COG5002	protein histidine kinase activity
KQ224_RS10410	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KQ224_RS10425	COG3842	ATPase activity
KQ224_RS10455	COG0488	(ABC) transporter
KQ224_RS10465	COG2226	methyltransferase
KQ224_RS10470	COG5416	Lipopolysaccharide assembly protein A domain
KQ224_RS10480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KQ224_RS10485	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KQ224_RS10490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KQ224_RS10495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ224_RS10500	COG0517	IMP dehydrogenase activity
KQ224_RS10515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KQ224_RS10520	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KQ224_RS10525	COG0470	DNA polymerase III
KQ224_RS10530	COG4467	Involved in initiation control of chromosome replication
KQ224_RS10550	COG1674	ftsk spoiiie
KQ224_RS10560	COG2946	Replication initiation factor
KQ224_RS10590	COG0791	NLP P60 protein
KQ224_RS10590	COG0741	lytic transglycosylase activity
KQ224_RS10640	COG0583	DNA-binding transcription factor activity
KQ224_RS10650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ224_RS10655	COG0765	amino acid transport
KQ224_RS10660	COG0765	amino acid transport
KQ224_RS10665	COG1126	abc transporter atp-binding protein
KQ224_RS10670	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KQ224_RS10680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KQ224_RS10685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ224_RS10700	COG0708	Exodeoxyribonuclease III
KQ224_RS10710	COG0531	amino acid
KQ224_RS10730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KQ224_RS10775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ224_RS10775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ224_RS10800	COG4122	O-methyltransferase activity
KQ224_RS10805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KQ224_RS10815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KQ224_RS10820	COG1442	glycosyl transferase family 8
KQ224_RS10825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQ224_RS10845	COG1476	TRANSCRIPTIONal
KQ224_RS10870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KQ224_RS10875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KQ224_RS10880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KQ224_RS10885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KQ224_RS10890	COG0372	Belongs to the citrate synthase family
KQ224_RS10895	COG0538	isocitrate dehydrogenase activity
KQ224_RS10900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ224_RS10925	COG1196	nuclear chromosome segregation
KQ224_RS10930	COG0561	phosphatase activity
KQ224_RS10935	COG0561	phosphatase activity
KQ224_RS10940	COG0552	protein localization to endoplasmic reticulum
KQ224_RS10950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KQ224_RS10955	COG3689	TIGRFAM TIGR03943 family protein
KQ224_RS10960	COG0701	Predicted permease
KQ224_RS10975	COG1597	lipid kinase activity
KQ224_RS10985	COG0356	it plays a direct role in the translocation of protons across the membrane
KQ224_RS10990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KQ224_RS10995	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KQ224_RS11000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KQ224_RS11005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KQ224_RS11010	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KQ224_RS11015	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KQ224_RS11025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KQ224_RS11050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ224_RS11050	COG0072	phenylalanine-tRNA ligase activity
KQ224_RS11075	COG1051	belongs to the nudix hydrolase family
KQ224_RS11080	COG0302	gtp cyclohydrolase
KQ224_RS11110	COG1902	pentaerythritol trinitrate reductase activity
KQ224_RS11125	COG3655	Transcriptional regulator
KQ224_RS11165	COG1309	transcriptional regulator
KQ224_RS11180	COG1573	uracil-dna glycosylase
KQ224_RS11200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ224_RS11220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KQ224_RS11225	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KQ224_RS11235	COG1272	protein, Hemolysin III
KQ224_RS11245	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ224_RS11250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KQ224_RS11255	COG1937	Protein conserved in bacteria
KQ224_RS11260	COG0110	maltose O-acetyltransferase activity
KQ224_RS11265	COG0758	DNA mediated transformation
KQ224_RS11270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KQ224_RS11275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KQ224_RS11280	COG0222	ribosome binding
KQ224_RS11435	COG3711	transcriptional antiterminator
KQ224_RS11525	COG0745	RESPONSE REGULATOR receiver
KQ224_RS11530	COG2132	Multicopper oxidase
KQ224_RS11575	COG1396	sequence-specific DNA binding
KQ224_RS11605	COG2610	gluconate transmembrane transporter activity