locus-tag	class	description
N2A94_RS00005	COG1475	DNA binding
N2A94_RS00010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N2A94_RS00040	COG0488	(ABC) transporter
N2A94_RS00045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N2A94_RS00055	COG0516	GMP reductase activity
N2A94_RS00055	COG0517	IMP dehydrogenase activity
N2A94_RS00060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N2A94_RS00075	COG0612	Peptidase, M16
N2A94_RS00085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N2A94_RS00105	COG0741	lytic transglycosylase activity
N2A94_RS00115	COG1760	l-serine dehydratase
N2A94_RS00120	COG1760	l-serine dehydratase
N2A94_RS00150	COG0359	binds to the 23S rRNA
N2A94_RS00155	COG0305	Participates in initiation and elongation during chromosome replication
N2A94_RS00190	COG1309	transcriptional regulator
N2A94_RS00195	COG3759	membrane
N2A94_RS00210	COG1695	Transcriptional regulator
N2A94_RS00220	COG0701	Predicted permease
N2A94_RS00230	COG1250	3-hydroxyacyl-CoA dehydrogenase
N2A94_RS00235	COG1960	acyl-CoA dehydrogenase activity
N2A94_RS00240	COG0183	Belongs to the thiolase family
N2A94_RS00245	COG1250	3-hydroxyacyl-CoA dehydrogenase
N2A94_RS00250	COG0318	PFAM AMP-dependent synthetase and ligase
N2A94_RS00260	COG2508	Transcriptional regulator
N2A94_RS00285	COG2816	NAD+ diphosphatase activity
N2A94_RS00315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N2A94_RS00320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N2A94_RS00325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N2A94_RS00330	COG0018	arginyl-trna synthetase
N2A94_RS00335	COG1438	arginine binding
N2A94_RS00345	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N2A94_RS00445	COG0582	viral genome integration into host DNA
N2A94_RS00460	COG0632	four-way junction helicase activity
N2A94_RS00465	COG0519	Catalyzes the synthesis of GMP from XMP
N2A94_RS00475	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N2A94_RS00480	COG1393	Belongs to the ArsC family
N2A94_RS00485	COG4472	Bacterial protein of unknown function (DUF965)
N2A94_RS00490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N2A94_RS00495	COG3906	Belongs to the UPF0473 family
N2A94_RS00505	COG1328	CTP reductase activity
N2A94_RS00525	COG0602	queuosine metabolic process
N2A94_RS00530	COG3022	response to hydroperoxide
N2A94_RS00535	COG2514	catechol 2,3-dioxygenase activity
N2A94_RS00540	COG1733	regulation of RNA biosynthetic process
N2A94_RS00545	COG2188	Transcriptional regulator
N2A94_RS00550	COG1263	PTS System
N2A94_RS00550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N2A94_RS00555	COG0366	Alpha amylase catalytic
N2A94_RS00560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N2A94_RS00575	COG3959	Transketolase, thiamine diphosphate binding domain
N2A94_RS00580	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N2A94_RS00585	COG3590	peptidase
N2A94_RS00590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N2A94_RS00620	COG0400	carboxylic ester hydrolase activity
N2A94_RS00625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N2A94_RS00630	COG0346	lactoylglutathione lyase activity
N2A94_RS00635	COG0346	lactoylglutathione lyase activity
N2A94_RS00640	COG0025	NhaP-type Na H and K H
N2A94_RS00670	COG0459	protein refolding
N2A94_RS00700	COG0564	pseudouridine synthase activity
N2A94_RS00715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N2A94_RS00740	COG0495	leucyl-tRNA aminoacylation
N2A94_RS00745	COG1929	Belongs to the glycerate kinase type-1 family
N2A94_RS00770	COG3623	hexulose-6-phosphate isomerase
N2A94_RS00795	COG3448	diguanylate cyclase activity
N2A94_RS00795	COG4175	Glycine betaine
N2A94_RS00805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N2A94_RS00805	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N2A94_RS00810	COG1832	CoA-binding protein
N2A94_RS00825	COG0343	queuine tRNA-ribosyltransferase activity
N2A94_RS00835	COG1268	BioY protein
N2A94_RS00840	COG1234	tRNA 3'-trailer cleavage
N2A94_RS00860	COG0166	Belongs to the GPI family
N2A94_RS00870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N2A94_RS00870	COG3711	transcriptional antiterminator
N2A94_RS00880	COG3730	PTS system glucitol sorbitol-specific
N2A94_RS00885	COG3732	PTS system glucitol sorbitol-specific
N2A94_RS00895	COG2171	N-acyltransferase activity
N2A94_RS00900	COG1473	amidohydrolase
N2A94_RS00905	COG1215	transferase activity, transferring glycosyl groups
N2A94_RS00910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N2A94_RS00920	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N2A94_RS00930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N2A94_RS00935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N2A94_RS00945	COG1132	(ABC) transporter
N2A94_RS00950	COG1132	(ABC) transporter
N2A94_RS00955	COG0431	NADPH-dependent FMN reductase
N2A94_RS00955	COG3976	FMN-binding domain protein
N2A94_RS00955	COG1053	succinate dehydrogenase
N2A94_RS00965	COG2832	Protein of unknown function (DUF454)
N2A94_RS00970	COG0756	dUTP diphosphatase activity
N2A94_RS01000	COG3290	protein histidine kinase activity
N2A94_RS01020	COG0137	argininosuccinate synthase activity
N2A94_RS01025	COG0165	Argininosuccinate lyase
N2A94_RS01130	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
N2A94_RS01370	COG1114	Component of the transport system for branched-chain amino acids
N2A94_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
N2A94_RS01395	COG0673	inositol 2-dehydrogenase activity
N2A94_RS01400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N2A94_RS01415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N2A94_RS01465	COG0081	regulation of translation
N2A94_RS01500	COG1702	phosphate starvation-inducible protein PhoH
N2A94_RS01505	COG1573	uracil-dna glycosylase
N2A94_RS01510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N2A94_RS01515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N2A94_RS01525	COG0494	nUDIX hydrolase
N2A94_RS01540	COG1131	(ABC) transporter
N2A94_RS01565	COG2364	Membrane
N2A94_RS01570	COG0433	COG0433 Predicted ATPase
N2A94_RS01575	COG2814	Major facilitator Superfamily
N2A94_RS01590	COG0557	exoribonuclease II activity
N2A94_RS01595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N2A94_RS01600	COG0346	lactoylglutathione lyase activity
N2A94_RS01605	COG0778	Nitroreductase
N2A94_RS01610	COG2723	6-phospho-beta-galactosidase activity
N2A94_RS01625	COG3711	transcriptional antiterminator
N2A94_RS01625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N2A94_RS01630	COG1447	Phosphotransferase system cellobiose-specific component IIA
N2A94_RS01660	COG1609	Transcriptional regulator
N2A94_RS01675	COG0438	transferase activity, transferring glycosyl groups
N2A94_RS01680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N2A94_RS01690	COG2376	Dihydroxyacetone kinase
N2A94_RS01700	COG2376	Dihydroxyacetone kinase
N2A94_RS01705	COG1461	Dihydroxyacetone kinase
N2A94_RS01710	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
N2A94_RS01715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N2A94_RS01725	COG0765	amino acid transport
N2A94_RS01730	COG0765	amino acid transport
N2A94_RS01735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N2A94_RS01745	COG0745	RESPONSE REGULATOR receiver
N2A94_RS01750	COG5002	protein histidine kinase activity
N2A94_RS01755	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N2A94_RS01760	COG0571	ribonuclease III activity
N2A94_RS01765	COG1196	nuclear chromosome segregation
N2A94_RS01770	COG0561	phosphatase activity
N2A94_RS01775	COG0561	phosphatase activity
N2A94_RS01780	COG0552	protein localization to endoplasmic reticulum
N2A94_RS01790	COG2814	Major facilitator Superfamily
N2A94_RS01795	COG3689	TIGRFAM TIGR03943 family protein
N2A94_RS01800	COG0701	Predicted permease
N2A94_RS01810	COG0346	lactoylglutathione lyase activity
N2A94_RS01815	COG0745	RESPONSE REGULATOR receiver
N2A94_RS01820	COG5002	protein histidine kinase activity
N2A94_RS01825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N2A94_RS01830	COG0573	inorganic phosphate transmembrane transporter activity
N2A94_RS01840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N2A94_RS01845	COG0704	Plays a role in the regulation of phosphate uptake
N2A94_RS01850	COG2183	response to ionizing radiation
N2A94_RS01865	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
N2A94_RS01895	COG0826	peptidase U32
N2A94_RS01905	COG4443	Transcriptional Coactivator p15 (PC4)
N2A94_RS01910	COG4166	transmembrane transport
N2A94_RS01930	COG1228	amidohydrolase
N2A94_RS01935	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N2A94_RS01945	COG3404	Formiminotransferase-cyclodeaminase
N2A94_RS01960	COG0531	amino acid
N2A94_RS01965	COG2986	histidine ammonia-lyase
N2A94_RS01970	COG0010	Belongs to the arginase family
N2A94_RS01995	COG3304	Inner membrane component domain
N2A94_RS02005	COG3859	Proton-coupled thiamine transporter YuaJ
N2A94_RS02025	COG1164	Oligoendopeptidase f
N2A94_RS02035	COG0772	Belongs to the SEDS family
N2A94_RS02055	COG2348	transferase activity, transferring amino-acyl groups
N2A94_RS02065	COG1078	dGTPase activity
N2A94_RS02085	COG0584	glycerophosphoryl diester phosphodiesterase
N2A94_RS02100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N2A94_RS02105	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
N2A94_RS02110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N2A94_RS02120	COG2884	Cell division ATP-binding protein ftsE
N2A94_RS02125	COG2177	Part of the ABC transporter FtsEX involved in
N2A94_RS02140	COG0436	Aminotransferase
N2A94_RS02145	COG0017	Asparaginyl-tRNA synthetase
N2A94_RS02155	COG1660	Displays ATPase and GTPase activities
N2A94_RS02180	COG2188	Transcriptional regulator
N2A94_RS02185	COG2222	sugar isomerase
N2A94_RS02210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N2A94_RS02210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N2A94_RS02215	COG3715	PTS system
N2A94_RS02220	COG3716	PTS system mannose fructose sorbose family IID component
N2A94_RS02240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N2A94_RS02245	COG2153	protein acetylation
N2A94_RS02250	COG0625	glutathione transferase activity
N2A94_RS02260	COG0716	FMN binding
N2A94_RS02265	COG1605	Chorismate mutase
N2A94_RS02265	COG0077	Prephenate dehydratase
N2A94_RS02270	COG0038	chloride channel
N2A94_RS02275	COG0335	large ribosomal subunit rRNA binding
N2A94_RS02290	COG0772	Belongs to the SEDS family
N2A94_RS02305	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
N2A94_RS02310	COG0560	Phosphoserine phosphatase
N2A94_RS02330	COG0148	phosphopyruvate hydratase activity
N2A94_RS02335	COG2031	fatty acid transporter
N2A94_RS02345	COG0183	Belongs to the thiolase family
N2A94_RS02370	COG1269	ATP hydrolysis coupled proton transport
N2A94_RS02375	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N2A94_RS02390	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
N2A94_RS02410	COG0778	Nitroreductase
N2A94_RS02420	COG4708	membrane
N2A94_RS02425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N2A94_RS02430	COG1597	lipid kinase activity
N2A94_RS02435	COG1523	belongs to the glycosyl hydrolase 13 family
N2A94_RS02440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N2A94_RS02445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N2A94_RS02450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N2A94_RS02455	COG0297	glycogen (starch) synthase activity
N2A94_RS02460	COG0058	SHG alpha-glucan phosphorylase activity
N2A94_RS02480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N2A94_RS02490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N2A94_RS02495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N2A94_RS02500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N2A94_RS02510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N2A94_RS02535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N2A94_RS02535	COG0072	phenylalanine-tRNA ligase activity
N2A94_RS02550	COG0577	efflux transmembrane transporter activity
N2A94_RS02555	COG1136	(ABC) transporter
N2A94_RS02560	COG2321	neutral zinc metallopeptidase
N2A94_RS02565	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
N2A94_RS02570	COG1074	ATP-dependent DNA helicase activity
N2A94_RS02575	COG0436	Aminotransferase
N2A94_RS02580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N2A94_RS02590	COG1970	mechanosensitive ion channel activity
N2A94_RS02595	COG0358	DNA primase activity
N2A94_RS02600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N2A94_RS02605	COG2151	metal-sulfur cluster biosynthetic enzyme
N2A94_RS02620	COG1442	glycosyl transferase family 8
N2A94_RS02620	COG1216	Glycosyl transferase, family 2
N2A94_RS02635	COG0438	transferase activity, transferring glycosyl groups
N2A94_RS02645	COG1368	sulfuric ester hydrolase activity
N2A94_RS02655	COG0463	Glycosyl transferase, family 2
N2A94_RS02660	COG2246	polysaccharide biosynthetic process
N2A94_RS02700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N2A94_RS02705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N2A94_RS02710	COG1368	sulfuric ester hydrolase activity
N2A94_RS02715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N2A94_RS02735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N2A94_RS02740	COG0285	dihydrofolate synthase activity
N2A94_RS02750	COG1104	cysteine desulfurase activity
N2A94_RS02755	COG0301	tRNA thio-modification
N2A94_RS02775	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N2A94_RS02780	COG0583	DNA-binding transcription factor activity
N2A94_RS02790	COG0564	pseudouridine synthase activity
N2A94_RS02795	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N2A94_RS02825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N2A94_RS02830	COG1136	(ABC) transporter
N2A94_RS02835	COG0577	efflux transmembrane transporter activity
N2A94_RS02845	COG0228	four-way junction DNA binding
N2A94_RS02850	COG1837	Belongs to the UPF0109 family
N2A94_RS02875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N2A94_RS02880	COG0336	Belongs to the RNA methyltransferase TrmD family
N2A94_RS02900	COG1349	DNA-binding transcription factor activity
N2A94_RS02905	COG1105	Belongs to the carbohydrate kinase PfkB family
N2A94_RS02910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N2A94_RS02910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N2A94_RS02910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N2A94_RS02915	COG3942	CHAP domain
N2A94_RS02915	COG1705	Flagellar rod assembly protein muramidase FlgJ
N2A94_RS02920	COG1388	LysM domain
N2A94_RS02920	COG1705	Flagellar rod assembly protein muramidase FlgJ
N2A94_RS02940	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N2A94_RS02950	COG0488	(ABC) transporter
N2A94_RS02965	COG1132	(ABC) transporter
N2A94_RS02970	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N2A94_RS02975	COG0242	peptide deformylase activity
N2A94_RS03015	COG3425	synthase
N2A94_RS03025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N2A94_RS03030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N2A94_RS03050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N2A94_RS03055	COG0222	ribosome binding
N2A94_RS03070	COG0463	Glycosyl transferase, family 2
N2A94_RS03085	COG1486	melibiose metabolic process
N2A94_RS03090	COG1737	Transcriptional regulator
N2A94_RS03095	COG0446	pyridine nucleotide-disulphide oxidoreductase
N2A94_RS03100	COG0366	Alpha amylase catalytic
N2A94_RS03110	COG0726	polysaccharide deacetylase
N2A94_RS03115	COG0460	homoserine dehydrogenase
N2A94_RS03120	COG0083	homoserine kinase activity
N2A94_RS03125	COG0285	dihydrofolate synthase activity
N2A94_RS03130	COG0302	gtp cyclohydrolase
N2A94_RS03150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N2A94_RS03160	COG1176	ABC-type spermidine putrescine transport system, permease component I
N2A94_RS03165	COG1177	transmembrane transport
N2A94_RS03175	COG4565	transcriptional regulatory protein
N2A94_RS03180	COG3290	protein histidine kinase activity
N2A94_RS03185	COG3493	citrate carrier protein
N2A94_RS03195	COG0038	chloride channel
N2A94_RS03200	COG3711	transcriptional antiterminator
N2A94_RS03205	COG2190	(PTS) system
N2A94_RS03205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N2A94_RS03205	COG1263	PTS System
N2A94_RS03210	COG2272	Belongs to the type-B carboxylesterase lipase family
N2A94_RS03215	COG2207	Transcriptional regulator
N2A94_RS03220	COG2723	6-phospho-beta-galactosidase activity
N2A94_RS03230	COG0561	phosphatase activity
N2A94_RS03235	COG2723	6-phospho-beta-galactosidase activity
N2A94_RS03245	COG0406	alpha-ribazole phosphatase activity
N2A94_RS03255	COG2723	6-phospho-beta-galactosidase activity
N2A94_RS03260	COG0628	permease
N2A94_RS03265	COG2003	Belongs to the UPF0758 family
N2A94_RS03290	COG1104	cysteine desulfurase activity
N2A94_RS03305	COG2357	RelA SpoT domain protein
N2A94_RS03315	COG0564	pseudouridine synthase activity
N2A94_RS03320	COG0280	phosphate acetyltransferase
N2A94_RS03325	COG4221	oxidoreductase activity
N2A94_RS03330	COG0477	Major facilitator Superfamily
N2A94_RS03360	COG1174	glycine betaine transport
N2A94_RS03365	COG2723	6-phospho-beta-galactosidase activity
N2A94_RS03370	COG0516	GMP reductase activity
N2A94_RS03375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N2A94_RS03380	COG2233	PERMEase
N2A94_RS03405	COG2890	protein-(glutamine-N5) methyltransferase activity
N2A94_RS03410	COG0009	L-threonylcarbamoyladenylate synthase
N2A94_RS03420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N2A94_RS03440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N2A94_RS03445	COG0039	L-malate dehydrogenase activity
N2A94_RS03455	COG3764	Sortase (surface protein transpeptidase)
N2A94_RS03460	COG0346	lactoylglutathione lyase activity
N2A94_RS03470	COG0803	Belongs to the bacterial solute-binding protein 9 family
N2A94_RS03480	COG1811	Na channel or pump
N2A94_RS03490	COG0386	Belongs to the glutathione peroxidase family
N2A94_RS03500	COG2188	Transcriptional regulator
N2A94_RS03510	COG2723	6-phospho-beta-galactosidase activity
N2A94_RS03515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N2A94_RS03530	COG3104	oligopeptide transport
N2A94_RS03550	COG2188	Transcriptional regulator
N2A94_RS03560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N2A94_RS03575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N2A94_RS03585	COG0673	inositol 2-dehydrogenase activity
N2A94_RS03600	COG0561	phosphatase activity
N2A94_RS03615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N2A94_RS03615	COG2190	(PTS) system
N2A94_RS03615	COG1263	PTS System
N2A94_RS03620	COG2723	6-phospho-beta-galactosidase activity
N2A94_RS03630	COG0662	Cupin 2, conserved barrel domain protein
N2A94_RS03635	COG3976	FMN-binding domain protein
N2A94_RS03635	COG1053	succinate dehydrogenase
N2A94_RS03635	COG0431	NADPH-dependent FMN reductase
N2A94_RS03675	COG4974	Belongs to the 'phage' integrase family
N2A94_RS03680	COG1902	pentaerythritol trinitrate reductase activity
N2A94_RS03705	COG1378	Sugar-specific transcriptional regulator TrmB
N2A94_RS03710	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
N2A94_RS03725	COG0642	Histidine kinase
N2A94_RS03740	COG1136	(ABC) transporter
N2A94_RS03750	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N2A94_RS03775	COG0583	DNA-binding transcription factor activity
N2A94_RS03780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N2A94_RS03785	COG0758	DNA mediated transformation
N2A94_RS03790	COG0110	maltose O-acetyltransferase activity
N2A94_RS03795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N2A94_RS03800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N2A94_RS03810	COG0095	Lipoate-protein ligase
N2A94_RS03815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N2A94_RS03830	COG1272	protein, Hemolysin III
N2A94_RS03850	COG0488	(ABC) transporter
N2A94_RS03855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N2A94_RS03860	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N2A94_RS03860	COG1328	CTP reductase activity
N2A94_RS03865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N2A94_RS03870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N2A94_RS03875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N2A94_RS03885	COG2759	Belongs to the formate--tetrahydrofolate ligase family
N2A94_RS03895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N2A94_RS03900	COG4684	Psort location CytoplasmicMembrane, score
N2A94_RS03905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N2A94_RS03910	COG1079	Belongs to the binding-protein-dependent transport system permease family
N2A94_RS03915	COG4603	Belongs to the binding-protein-dependent transport system permease family
N2A94_RS03920	COG3845	ABC transporter
N2A94_RS03925	COG1744	ABC transporter substrate-binding protein PnrA-like
N2A94_RS03930	COG0295	cytidine deaminase activity
N2A94_RS03935	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N2A94_RS03940	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N2A94_RS03945	COG2813	Specifically methylates the guanine in position
N2A94_RS03960	COG5002	protein histidine kinase activity
N2A94_RS03965	COG0745	RESPONSE REGULATOR receiver
N2A94_RS03975	COG0704	Plays a role in the regulation of phosphate uptake
N2A94_RS03990	COG0581	inorganic phosphate transmembrane transporter activity
N2A94_RS03995	COG0573	inorganic phosphate transmembrane transporter activity
N2A94_RS04005	COG0483	inositol monophosphate 1-phosphatase activity
N2A94_RS04010	COG4476	Belongs to the UPF0223 family
N2A94_RS04020	COG0196	riboflavin kinase activity
N2A94_RS04095	COG2261	transglycosylase associated protein
N2A94_RS04115	COG1115	amino acid carrier protein
N2A94_RS04120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N2A94_RS04125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N2A94_RS04130	COG1126	abc transporter atp-binding protein
N2A94_RS04135	COG0765	amino acid transport
N2A94_RS04140	COG2824	Alkylphosphonate utilization operon protein PhnA
N2A94_RS04145	COG0246	Mannitol dehydrogenase
N2A94_RS04150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N2A94_RS04155	COG3711	transcriptional antiterminator
N2A94_RS04160	COG2213	PTS system mannitol-specific
N2A94_RS04175	COG0469	pyruvate kinase activity
N2A94_RS04180	COG0205	6-phosphofructokinase activity
N2A94_RS04190	COG1725	Transcriptional regulator
N2A94_RS04195	COG1131	(ABC) transporter
N2A94_RS04270	COG5280	Phage tail tape measure protein TP901
N2A94_RS04270	COG3953	SLT domain
N2A94_RS04520	COG0539	negative regulation of cytoplasmic translation
N2A94_RS04540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N2A94_RS04550	COG0187	DNA topoisomerase II activity
N2A94_RS04565	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N2A94_RS04570	COG0765	amino acid transport
N2A94_RS04575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N2A94_RS04585	COG1881	PFAM PEBP family protein
N2A94_RS04650	COG0438	transferase activity, transferring glycosyl groups
N2A94_RS04665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N2A94_RS04670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N2A94_RS04695	COG1316	TRANSCRIPTIONal
N2A94_RS04730	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
N2A94_RS04740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N2A94_RS04750	COG0322	excinuclease ABC activity
N2A94_RS04760	COG0561	phosphatase activity
N2A94_RS04765	COG1012	belongs to the aldehyde dehydrogenase family
N2A94_RS04770	COG1011	Hydrolase
N2A94_RS04780	COG2259	Doxx family
N2A94_RS04810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N2A94_RS04820	COG0789	Transcriptional regulator
N2A94_RS04830	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N2A94_RS04845	COG0656	L-ascorbic acid biosynthetic process
N2A94_RS04860	COG1418	mRNA catabolic process
N2A94_RS04875	COG0481	GTPase activity
N2A94_RS04895	COG0647	UMP catabolic process
N2A94_RS04905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N2A94_RS04915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N2A94_RS04930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N2A94_RS04935	COG3442	glutamine amidotransferase
N2A94_RS04940	COG0095	Lipoate-protein ligase
N2A94_RS04945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N2A94_RS04950	COG0508	dehydrogenase complex catalyzes the overall conversion of
N2A94_RS04955	COG0022	dehydrogenase e1 component
N2A94_RS04955	COG0508	dehydrogenase complex catalyzes the overall conversion of
N2A94_RS04960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N2A94_RS04965	COG0488	(ABC) transporter
N2A94_RS04985	COG3842	ATPase activity
N2A94_RS05000	COG1293	RNA-binding protein homologous to eukaryotic snRNP
N2A94_RS05005	COG3527	Alpha-acetolactate decarboxylase
N2A94_RS05010	COG0028	Belongs to the TPP enzyme family
N2A94_RS05015	COG0457	Tetratricopeptide repeat
N2A94_RS05020	COG0628	permease
N2A94_RS05025	COG1051	belongs to the nudix hydrolase family
N2A94_RS05030	COG2706	6-phosphogluconolactonase activity
N2A94_RS05040	COG1088	dTDP-glucose 4,6-dehydratase activity
N2A94_RS05050	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
N2A94_RS05055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N2A94_RS05070	COG2384	SAM-dependent methyltransferase
N2A94_RS05080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N2A94_RS05090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N2A94_RS05095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N2A94_RS05095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N2A94_RS05100	COG0300	oxidoreductase activity
N2A94_RS05105	COG1234	tRNA 3'-trailer cleavage
N2A94_RS05115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N2A94_RS05120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N2A94_RS05140	COG1054	Belongs to the UPF0176 family
N2A94_RS05160	COG0058	SHG alpha-glucan phosphorylase activity
N2A94_RS05165	COG1640	4-alpha-glucanotransferase
N2A94_RS05170	COG1609	Transcriptional regulator
N2A94_RS05180	COG1175	transmembrane transport
N2A94_RS05185	COG3833	ABC-type maltose transport systems, permease component
N2A94_RS05195	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
N2A94_RS05205	COG1696	Membrane protein involved in D-alanine export
N2A94_RS05220	COG0556	nucleotide-excision repair
N2A94_RS05225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N2A94_RS05230	COG1126	abc transporter atp-binding protein
N2A94_RS05235	COG0488	(ABC) transporter
N2A94_RS05250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N2A94_RS05260	COG2309	aminopeptidase activity
N2A94_RS05265	COG0598	Magnesium transport protein CorA
N2A94_RS05270	COG1187	pseudouridine synthase activity
N2A94_RS05280	COG2814	Major facilitator Superfamily
N2A94_RS05290	COG0390	transport system, permease component
N2A94_RS05295	COG4619	ABC transporter
N2A94_RS05305	COG0583	DNA-binding transcription factor activity
N2A94_RS05310	COG0183	Belongs to the thiolase family
N2A94_RS05315	COG1024	Enoyl-CoA hydratase
N2A94_RS05315	COG1250	3-hydroxyacyl-CoA dehydrogenase
N2A94_RS05320	COG0427	acetyl-CoA hydrolase
N2A94_RS05325	COG1960	acyl-CoA dehydrogenase activity
N2A94_RS05330	COG0318	PFAM AMP-dependent synthetase and ligase
N2A94_RS05365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N2A94_RS05380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N2A94_RS05405	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N2A94_RS05415	COG0024	Methionine aminopeptidase
N2A94_RS05420	COG4109	DRTGG domain
N2A94_RS05440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N2A94_RS05455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N2A94_RS05460	COG1956	GAF domain-containing protein
N2A94_RS05470	COG0572	uridine kinase
N2A94_RS05480	COG0726	polysaccharide deacetylase
N2A94_RS05500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N2A94_RS05505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N2A94_RS05510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N2A94_RS05530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N2A94_RS05535	COG4122	O-methyltransferase activity
N2A94_RS05545	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
N2A94_RS05565	COG4721	ABC-type cobalt transport system, permease component
N2A94_RS05575	COG2223	nitrite transmembrane transporter activity
N2A94_RS05580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N2A94_RS05600	COG1187	pseudouridine synthase activity
N2A94_RS05605	COG0363	glucosamine-6-phosphate deaminase activity
N2A94_RS05630	COG0658	competence protein
N2A94_RS05630	COG2333	competence protein COMEC
N2A94_RS05640	COG0204	Acyl-transferase
N2A94_RS05645	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N2A94_RS05660	COG0513	Belongs to the DEAD box helicase family
N2A94_RS05665	COG0561	phosphatase activity
N2A94_RS05680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N2A94_RS05700	COG0768	penicillin binding
N2A94_RS05705	COG2116	formate transmembrane transporter activity
N2A94_RS05725	COG0167	dihydroorotate dehydrogenase activity
N2A94_RS05735	COG2217	Heavy metal translocating P-type atpase
N2A94_RS05750	COG2755	lipolytic protein G-D-S-L family
N2A94_RS05760	COG0497	DNA recombination
N2A94_RS05770	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
N2A94_RS05790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N2A94_RS05795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N2A94_RS05815	COG1126	abc transporter atp-binding protein
N2A94_RS05820	COG0765	amino acid transport
N2A94_RS05825	COG4703	Protein of unknown function (DUF1797)
N2A94_RS05830	COG0542	response to heat
N2A94_RS05850	COG3599	regulation of cell shape
N2A94_RS05865	COG1799	cell septum assembly
N2A94_RS05870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N2A94_RS05895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N2A94_RS05905	COG1217	gtp-binding protein TYPA
N2A94_RS05910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N2A94_RS05915	COG1940	carbohydrate kinase activity
N2A94_RS05925	COG0783	Belongs to the Dps family
N2A94_RS05930	COG1132	(ABC) transporter
N2A94_RS05935	COG1132	(ABC) transporter
N2A94_RS05945	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N2A94_RS05955	COG0737	Belongs to the 5'-nucleotidase family
N2A94_RS05960	COG1879	ABC-type sugar transport system periplasmic component
N2A94_RS05965	COG1172	Belongs to the binding-protein-dependent transport system permease family
N2A94_RS05970	COG1129	ABC transporter
N2A94_RS05975	COG1869	D-ribose catabolic process
N2A94_RS05980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N2A94_RS05985	COG1609	Transcriptional regulator
N2A94_RS05990	COG3480	Lon protease (S16) C-terminal proteolytic domain
N2A94_RS05995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N2A94_RS06000	COG0742	ribosomal rna small subunit methyltransferase
N2A94_RS06005	COG2502	aspartate--ammonia ligase
N2A94_RS06010	COG0549	Belongs to the carbamate kinase family
N2A94_RS06015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N2A94_RS06020	COG1288	antiporter activity
N2A94_RS06025	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N2A94_RS06030	COG0454	-acetyltransferase
N2A94_RS06035	COG2235	arginine
N2A94_RS06090	COG5492	domain, Protein
N2A94_RS06095	COG1609	Transcriptional regulator
N2A94_RS06105	COG3716	PTS system mannose fructose sorbose family IID component
N2A94_RS06110	COG3715	PTS system
N2A94_RS06115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N2A94_RS06120	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N2A94_RS06130	COG1028	Short-chain dehydrogenase reductase Sdr
N2A94_RS06180	COG0110	maltose O-acetyltransferase activity
N2A94_RS06225	COG1914	H( )-stimulated, divalent metal cation uptake system
N2A94_RS06230	COG1136	(ABC) transporter
N2A94_RS06235	COG0435	Glutathione S-transferase
N2A94_RS06245	COG4152	abc transporter atp-binding protein
N2A94_RS06250	COG1668	transmembrane transport
N2A94_RS06255	COG0586	Pfam SNARE associated Golgi protein
N2A94_RS06265	COG1053	succinate dehydrogenase
N2A94_RS06265	COG3976	FMN-binding domain protein
N2A94_RS06265	COG0431	NADPH-dependent FMN reductase
N2A94_RS06270	COG0710	3-dehydroquinate dehydratase activity
N2A94_RS06275	COG2851	Citrate transporter
N2A94_RS06285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N2A94_RS06290	COG2271	Major facilitator Superfamily
N2A94_RS06295	COG2271	Major facilitator Superfamily
N2A94_RS06300	COG1028	Short-chain dehydrogenase reductase Sdr
N2A94_RS06310	COG0583	DNA-binding transcription factor activity
N2A94_RS06315	COG4753	response regulator
N2A94_RS06315	COG2207	Transcriptional regulator
N2A94_RS06320	COG2972	Histidine kinase
N2A94_RS06330	COG1653	transport
N2A94_RS06335	COG0395	ABC-type sugar transport system, permease component
N2A94_RS06340	COG1175	transmembrane transport
N2A94_RS06345	COG1940	carbohydrate kinase activity
N2A94_RS06355	COG3525	Glycosyl hydrolase, family 20, catalytic domain
N2A94_RS06370	COG0383	alpha-mannosidase activity
N2A94_RS06405	COG2137	regulation of response to DNA damage stimulus
N2A94_RS06480	COG1040	competence protein
N2A94_RS06485	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
N2A94_RS06490	COG1739	Uncharacterized protein family UPF0029
N2A94_RS06500	COG1098	S1 RNA binding domain
N2A94_RS06510	COG2197	response regulator
N2A94_RS06515	COG4585	Histidine kinase
N2A94_RS06525	COG0515	serine threonine protein kinase
N2A94_RS06525	COG2815	serine threonine protein kinase
N2A94_RS06535	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N2A94_RS06535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N2A94_RS06540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N2A94_RS06545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N2A94_RS06565	COG1854	S-ribosylhomocysteine lyase activity
N2A94_RS06580	COG0116	Belongs to the methyltransferase superfamily
N2A94_RS06595	COG4474	Belongs to the UPF0398 family
N2A94_RS06600	COG3331	DNA recombination
N2A94_RS06605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N2A94_RS06610	COG3579	cysteine-type endopeptidase activity
N2A94_RS06615	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N2A94_RS06620	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N2A94_RS06835	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
N2A94_RS06905	COG3561	AntA/AntB antirepressor
N2A94_RS06940	COG1113	amino acid transport
N2A94_RS06945	COG0492	ferredoxin-NADP+ reductase activity
N2A94_RS06955	COG1126	abc transporter atp-binding protein
N2A94_RS06960	COG0765	amino acid transport
N2A94_RS06965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N2A94_RS06970	COG0513	Belongs to the DEAD box helicase family
N2A94_RS06975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N2A94_RS06980	COG0768	penicillin binding
N2A94_RS06990	COG0275	rRNA processing
N2A94_RS06995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N2A94_RS07000	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N2A94_RS07010	COG1131	(ABC) transporter
N2A94_RS07040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N2A94_RS07050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N2A94_RS07065	COG0751	glycine-tRNA ligase activity
N2A94_RS07070	COG0752	glycyl-tRNA synthetase alpha subunit
N2A94_RS07075	COG1755	Isoprenylcysteine carboxyl methyltransferase
N2A94_RS07080	COG0656	L-ascorbic acid biosynthetic process
N2A94_RS07105	COG0561	phosphatase activity
N2A94_RS07135	COG3775	system Galactitol-specific IIC component
N2A94_RS07160	COG2217	Heavy metal translocating P-type atpase
N2A94_RS07165	COG3682	Transcriptional regulator
N2A94_RS07185	COG2740	Nucleic-acid-binding protein implicated in transcription termination
N2A94_RS07190	COG0195	Participates in both transcription termination and antitermination
N2A94_RS07215	COG4473	ABC transporter
N2A94_RS07220	COG1131	(ABC) transporter
N2A94_RS07225	COG0537	adenosine 5'-monophosphoramidase activity
N2A94_RS07235	COG1316	TRANSCRIPTIONal
N2A94_RS07245	COG0802	atpase or kinase
N2A94_RS07250	COG2252	PERMEase
N2A94_RS07255	COG0561	phosphatase activity
N2A94_RS07265	COG3715	PTS system
N2A94_RS07270	COG3716	PTS system mannose fructose sorbose family IID component
N2A94_RS07285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N2A94_RS07305	COG0439	Biotin carboxylase
N2A94_RS07310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N2A94_RS07320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N2A94_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
N2A94_RS07330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N2A94_RS07345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N2A94_RS07350	COG1846	Transcriptional regulator
N2A94_RS07355	COG1024	Enoyl-CoA hydratase
N2A94_RS07375	COG1420	regulation of RNA biosynthetic process
N2A94_RS07390	COG0588	phosphoglycerate mutase activity
N2A94_RS07395	COG2848	UPF0210 protein
N2A94_RS07400	COG3830	Belongs to the UPF0237 family
N2A94_RS07420	COG2261	transglycosylase associated protein
N2A94_RS07445	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N2A94_RS07450	COG0574	Belongs to the PEP-utilizing enzyme family
N2A94_RS07450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N2A94_RS07455	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N2A94_RS07460	COG0517	IMP dehydrogenase activity
N2A94_RS07480	COG0446	pyridine nucleotide-disulphide oxidoreductase
N2A94_RS07485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N2A94_RS07490	COG1937	Protein conserved in bacteria
N2A94_RS07495	COG1335	isochorismatase
N2A94_RS07500	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N2A94_RS07505	COG0436	Aminotransferase
N2A94_RS07510	COG0589	response to stress
N2A94_RS07515	COG0561	phosphatase activity
N2A94_RS07520	COG0252	asparaginase activity
N2A94_RS07525	COG4989	oxidoreductase activity
N2A94_RS07530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N2A94_RS07535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N2A94_RS07540	COG0736	holo-[acyl-carrier-protein] synthase activity
N2A94_RS07545	COG0653	protein targeting
N2A94_RS07550	COG1482	cell wall glycoprotein biosynthetic process
N2A94_RS07555	COG2723	6-phospho-beta-galactosidase activity
N2A94_RS07560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N2A94_RS07570	COG1940	carbohydrate kinase activity
N2A94_RS07575	COG1263	PTS System
N2A94_RS07575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N2A94_RS07575	COG2190	(PTS) system
N2A94_RS07580	COG1621	beta-fructofuranosidase activity
N2A94_RS07585	COG1609	Transcriptional regulator
N2A94_RS07590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N2A94_RS07605	COG2131	deaminase
N2A94_RS07610	COG0006	proline dipeptidase activity
N2A94_RS07645	COG1194	a g-specific adenine glycosylase
N2A94_RS07655	COG3118	belongs to the thioredoxin family
N2A94_RS07660	COG1193	negative regulation of DNA recombination
N2A94_RS07675	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N2A94_RS07680	COG0681	Belongs to the peptidase S26 family
N2A94_RS07685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N2A94_RS07700	COG1882	Formate acetyltransferase
N2A94_RS07710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N2A94_RS07730	COG2936	dipeptidyl-peptidase activity
N2A94_RS07750	COG1940	carbohydrate kinase activity
N2A94_RS07765	COG0395	ABC-type sugar transport system, permease component
N2A94_RS07770	COG4209	transmembrane transport
N2A94_RS07775	COG1609	Transcriptional regulator
N2A94_RS07790	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N2A94_RS07815	COG3052	prosthetic group binding
N2A94_RS07825	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
N2A94_RS07830	COG0511	ligase activity, forming carbon-carbon bonds
N2A94_RS07840	COG2851	Citrate transporter
N2A94_RS07850	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
N2A94_RS07855	COG3180	Ammonia monooxygenase
N2A94_RS07860	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
N2A94_RS07865	COG0583	DNA-binding transcription factor activity
N2A94_RS07870	COG2851	Citrate transporter
N2A94_RS07875	COG2828	Protein conserved in bacteria
N2A94_RS07900	COG3655	Transcriptional regulator
N2A94_RS07910	COG2723	6-phospho-beta-galactosidase activity
N2A94_RS07915	COG2814	Major facilitator Superfamily
N2A94_RS07925	COG0673	inositol 2-dehydrogenase activity
N2A94_RS07930	COG2348	transferase activity, transferring amino-acyl groups
N2A94_RS07940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N2A94_RS07950	COG1028	Short-chain dehydrogenase reductase Sdr
N2A94_RS07960	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
N2A94_RS07965	COG1609	Transcriptional regulator
N2A94_RS07975	COG1136	(ABC) transporter
N2A94_RS07980	COG0577	efflux transmembrane transporter activity
N2A94_RS07990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N2A94_RS08000	COG2226	methyltransferase
N2A94_RS08005	COG3708	Transcriptional regulator
N2A94_RS08005	COG2207	Transcriptional regulator
N2A94_RS08015	COG3620	sequence-specific DNA binding
N2A94_RS08050	COG2176	DNA-directed DNA polymerase activity
N2A94_RS08060	COG2081	HI0933 family
N2A94_RS08080	COG1214	PFAM Peptidase M22, glycoprotease
N2A94_RS08085	COG5503	Protein of unknown function (DUF1447)
N2A94_RS08095	COG4608	Belongs to the ABC transporter superfamily
N2A94_RS08100	COG0444	Belongs to the ABC transporter superfamily
N2A94_RS08105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N2A94_RS08110	COG0601	transmembrane transport
N2A94_RS08115	COG4166	transmembrane transport
N2A94_RS08120	COG0174	glutamine synthetase
N2A94_RS08125	COG0789	Transcriptional regulator
N2A94_RS08135	COG0126	phosphoglycerate kinase activity
N2A94_RS08140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N2A94_RS08145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N2A94_RS08155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N2A94_RS08165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N2A94_RS08200	COG2814	Major facilitator Superfamily
N2A94_RS08210	COG2226	methyltransferase
N2A94_RS08225	COG0084	hydrolase, TatD family'
N2A94_RS08230	COG3711	transcriptional antiterminator
N2A94_RS08230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N2A94_RS08240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N2A94_RS08240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N2A94_RS08240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N2A94_RS08255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N2A94_RS08265	COG1653	transport
N2A94_RS08270	COG0395	ABC-type sugar transport system, permease component
N2A94_RS08280	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
N2A94_RS08305	COG1131	(ABC) transporter
N2A94_RS08315	COG1847	R3H domain protein
N2A94_RS08325	COG0594	ribonuclease P activity
N2A94_RS08545	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
N2A94_RS08605	COG3561	AntA/AntB antirepressor
N2A94_RS08645	COG0640	Transcriptional regulator
N2A94_RS08650	COG0708	Exodeoxyribonuclease III
N2A94_RS08660	COG0346	lactoylglutathione lyase activity
N2A94_RS08675	COG1393	Belongs to the ArsC family
N2A94_RS08685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N2A94_RS08695	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N2A94_RS08720	COG1774	PSP1 C-terminal conserved region
N2A94_RS08725	COG0470	DNA polymerase III
N2A94_RS08735	COG0517	IMP dehydrogenase activity
N2A94_RS08775	COG0740	serine-type endopeptidase activity
N2A94_RS08785	COG2244	polysaccharide biosynthetic process
N2A94_RS08795	COG1120	ATPase activity
N2A94_RS08800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N2A94_RS08805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N2A94_RS08810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N2A94_RS08825	COG1227	inorganic diphosphatase activity
N2A94_RS08830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
N2A94_RS08835	COG1253	flavin adenine dinucleotide binding
N2A94_RS08840	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
N2A94_RS08850	COG1131	(ABC) transporter
N2A94_RS08855	COG1242	4 iron, 4 sulfur cluster binding
N2A94_RS08865	COG3620	sequence-specific DNA binding
N2A94_RS08980	COG0671	phosphoesterase, PA-phosphatase related
N2A94_RS08985	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
N2A94_RS08995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N2A94_RS09000	COG1187	pseudouridine synthase activity
N2A94_RS09010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N2A94_RS09035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N2A94_RS09060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N2A94_RS09065	COG1254	Belongs to the acylphosphatase family
N2A94_RS09080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N2A94_RS09100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N2A94_RS09110	COG1484	DNA-dependent DNA replication
N2A94_RS09120	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N2A94_RS09130	COG0745	RESPONSE REGULATOR receiver
N2A94_RS09140	COG0501	Belongs to the peptidase M48B family
N2A94_RS09145	COG1704	LemA family
N2A94_RS09150	COG0357	Ribosomal RNA small subunit methyltransferase G
N2A94_RS09155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N2A94_RS09160	COG0569	domain protein
N2A94_RS09180	COG1464	Belongs to the NlpA lipoprotein family
N2A94_RS09185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N2A94_RS09200	COG0789	Transcriptional regulator
N2A94_RS09210	COG2226	methyltransferase
N2A94_RS09215	COG0799	negative regulation of ribosome biogenesis
N2A94_RS09220	COG1335	isochorismatase
N2A94_RS09230	COG1713	HD superfamily hydrolase involved in NAD metabolism
N2A94_RS09240	COG1534	Rna-binding protein
N2A94_RS09245	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N2A94_RS09250	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
N2A94_RS09295	COG0444	Belongs to the ABC transporter superfamily
N2A94_RS09300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N2A94_RS09305	COG0601	transmembrane transport
N2A94_RS09310	COG4166	transmembrane transport
N2A94_RS09315	COG1686	Belongs to the peptidase S11 family
N2A94_RS09325	COG1686	Belongs to the peptidase S11 family
N2A94_RS09330	COG0719	Fe-S assembly protein
N2A94_RS09340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N2A94_RS09345	COG0719	Fe-S assembly protein
N2A94_RS09355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N2A94_RS09375	COG0765	amino acid transport
N2A94_RS09380	COG1126	abc transporter atp-binding protein
N2A94_RS09435	COG1346	cytolysis
N2A94_RS09445	COG3279	Response regulator of the LytR AlgR family
N2A94_RS09450	COG3275	phosphorelay sensor kinase activity
N2A94_RS09460	COG3343	RNA polymerase activity
N2A94_RS09465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N2A94_RS09470	COG0544	peptidyl-prolyl cis-trans isomerase activity
N2A94_RS09475	COG0668	transmembrane transport
N2A94_RS09485	COG4720	Psort location CytoplasmicMembrane, score
N2A94_RS09490	COG0352	thiamine-phosphate diphosphorylase activity
N2A94_RS09490	COG0351	phosphomethylpyrimidine kinase
N2A94_RS09495	COG0101	tRNA pseudouridine synthase activity
N2A94_RS09500	COG0527	aspartate kinase activity
N2A94_RS09540	COG4720	Psort location CytoplasmicMembrane, score
N2A94_RS09545	COG1122	ATPase activity
N2A94_RS09570	COG1511	domain protein
N2A94_RS09585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
N2A94_RS09605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N2A94_RS09620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N2A94_RS09675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N2A94_RS09690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N2A94_RS09700	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
N2A94_RS09710	COG1045	serine acetyltransferase
N2A94_RS09725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N2A94_RS09735	COG0248	Ppx GppA phosphatase
N2A94_RS09735	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N2A94_RS09740	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N2A94_RS09745	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N2A94_RS09755	COG0242	peptide deformylase activity
N2A94_RS09795	COG4589	Belongs to the CDS family
N2A94_RS09805	COG1862	Preprotein translocase
N2A94_RS09815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N2A94_RS09820	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
N2A94_RS09825	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N2A94_RS09830	COG1609	Transcriptional regulator
N2A94_RS09840	COG0110	maltose O-acetyltransferase activity
N2A94_RS09850	COG3842	ATPase activity
N2A94_RS09870	COG1490	D-aminoacyl-tRNA deacylase activity
N2A94_RS09890	COG1363	Peptidase, m42
N2A94_RS09905	COG1263	PTS System
N2A94_RS09905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N2A94_RS09905	COG2190	(PTS) system
N2A94_RS09910	COG1609	Transcriptional regulator
N2A94_RS09925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N2A94_RS09930	COG2264	protein methyltransferase activity
N2A94_RS09960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N2A94_RS09980	COG3716	PTS system mannose fructose sorbose family IID component
N2A94_RS10005	COG2197	response regulator
N2A94_RS10010	COG4585	Histidine kinase
N2A94_RS10020	COG0561	phosphatase activity
N2A94_RS10035	COG0561	phosphatase activity
N2A94_RS10040	COG0673	inositol 2-dehydrogenase activity
N2A94_RS10045	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
N2A94_RS10050	COG1737	Transcriptional regulator
N2A94_RS10060	COG3716	PTS system mannose fructose sorbose family IID component
N2A94_RS10065	COG3715	PTS system
N2A94_RS10070	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N2A94_RS10075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N2A94_RS10095	COG0281	malic enzyme
N2A94_RS10100	COG0583	DNA-binding transcription factor activity
N2A94_RS10110	COG2217	Heavy metal translocating P-type atpase
N2A94_RS10115	COG4978	Transcriptional regulator
N2A94_RS10115	COG0789	Transcriptional regulator
N2A94_RS10130	COG2094	Belongs to the DNA glycosylase MPG family
N2A94_RS10135	COG1694	Mazg nucleotide pyrophosphohydrolase
N2A94_RS10155	COG0789	Transcriptional regulator
N2A94_RS10155	COG4978	Transcriptional regulator
N2A94_RS10160	COG1122	ATPase activity
N2A94_RS10215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N2A94_RS10235	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N2A94_RS10240	COG1785	Belongs to the alkaline phosphatase family
N2A94_RS10245	COG1309	transcriptional regulator
N2A94_RS10265	COG3842	ATPase activity
N2A94_RS10285	COG0395	ABC-type sugar transport system, permease component
N2A94_RS10290	COG1175	transmembrane transport
N2A94_RS10295	COG2076	Multidrug Resistance protein
N2A94_RS10310	COG1882	Formate acetyltransferase
N2A94_RS10320	COG2390	Transcriptional regulator
N2A94_RS10325	COG1349	DNA-binding transcription factor activity
N2A94_RS10330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
N2A94_RS10345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N2A94_RS10360	COG1181	Belongs to the D-alanine--D-alanine ligase family
N2A94_RS10360	COG2918	glutathione biosynthetic process
N2A94_RS10380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N2A94_RS10385	COG1428	Deoxynucleoside kinase
N2A94_RS10390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N2A94_RS10395	COG4120	Belongs to the binding-protein-dependent transport system permease family
N2A94_RS10415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N2A94_RS10420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N2A94_RS10430	COG1363	Peptidase, m42
N2A94_RS10435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N2A94_RS10440	COG1266	CAAX protease self-immunity
N2A94_RS10455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N2A94_RS10485	COG4537	Required for transformation and DNA binding
N2A94_RS10610	COG1475	DNA binding
N2A94_RS10755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N2A94_RS10760	COG1459	type II secretion system
N2A94_RS10765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N2A94_RS10775	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N2A94_RS10785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N2A94_RS10785	COG4499	WXG100 protein secretion system (Wss), protein YukC
N2A94_RS10795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N2A94_RS10800	COG1121	(ABC) transporter
N2A94_RS10810	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N2A94_RS10815	COG0142	geranyltranstransferase activity
N2A94_RS10820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N2A94_RS10825	COG4988	ABC transporter
N2A94_RS10830	COG1294	oxidase, subunit
N2A94_RS10835	COG1271	oxidase subunit
N2A94_RS10840	COG1252	NADH dehydrogenase
N2A94_RS10985	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N2A94_RS11005	COG0201	protein transport
N2A94_RS11010	COG0200	Binds to the 23S rRNA
N2A94_RS11015	COG1841	ribosomal large subunit assembly
N2A94_RS11045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N2A94_RS11055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N2A94_RS11070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N2A94_RS11075	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N2A94_RS11090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N2A94_RS11095	COG0089	rRNA binding
N2A94_RS11100	COG0088	Forms part of the polypeptide exit tunnel
N2A94_RS11110	COG0051	transcription antitermination factor activity, RNA binding
N2A94_RS11115	COG0534	Mate efflux family protein
N2A94_RS11130	COG1012	belongs to the aldehyde dehydrogenase family
N2A94_RS11130	COG1454	alcohol dehydrogenase
N2A94_RS11145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N2A94_RS11150	COG2255	four-way junction helicase activity
N2A94_RS11165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N2A94_RS11180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N2A94_RS11185	COG0151	Belongs to the GarS family
N2A94_RS11195	COG0138	bifunctional purine biosynthesis protein purh
N2A94_RS11200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N2A94_RS11205	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N2A94_RS11215	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N2A94_RS11220	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N2A94_RS11225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N2A94_RS11230	COG0416	fatty acid biosynthetic process
N2A94_RS11235	COG1381	Involved in DNA repair and RecF pathway recombination
N2A94_RS11240	COG0436	Aminotransferase
N2A94_RS11250	COG3942	CHAP domain
N2A94_RS11435	COG0531	amino acid
N2A94_RS11440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N2A94_RS11470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N2A94_RS11475	COG2244	polysaccharide biosynthetic process
N2A94_RS11480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N2A94_RS11485	COG0193	aminoacyl-tRNA hydrolase activity
N2A94_RS11490	COG0012	GTP binding
N2A94_RS11505	COG0592	DNA-directed DNA polymerase activity
N2A94_RS11510	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids