SPSF3K_RS09815 a95527c9d87289f7fca76b4b4992fc68 244 SUPERFAMILY SSF52540 1 223 4.77E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09815 a95527c9d87289f7fca76b4b4992fc68 244 SMART SM00382 26 217 1.1E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS09815 a95527c9d87289f7fca76b4b4992fc68 244 Gene3D G3DSA:3.40.50.300 1 236 1.8E-57 T 29-03-2018 SPSF3K_RS09815 a95527c9d87289f7fca76b4b4992fc68 244 Pfam PF00005 ABC transporter 17 160 6.2E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00710 b70d623b2923ad8d7664cd4f6a6f0601 774 SUPERFAMILY SSF53955 133 331 4.5E-67 T 29-03-2018 IPR023346 Lysozyme-like domain SPSF3K_RS00710 b70d623b2923ad8d7664cd4f6a6f0601 774 Gene3D G3DSA:3.40.710.10 338 751 7.5E-88 T 29-03-2018 SPSF3K_RS00710 b70d623b2923ad8d7664cd4f6a6f0601 774 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 154 693 3.4E-163 T 29-03-2018 SPSF3K_RS00710 b70d623b2923ad8d7664cd4f6a6f0601 774 SUPERFAMILY SSF56601 295 317 1.5E-97 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS00710 b70d623b2923ad8d7664cd4f6a6f0601 774 SUPERFAMILY SSF56601 350 706 1.5E-97 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS00710 b70d623b2923ad8d7664cd4f6a6f0601 774 Pfam PF00912 Transglycosylase 148 313 5.3E-58 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SPSF3K_RS00710 b70d623b2923ad8d7664cd4f6a6f0601 774 Gene3D G3DSA:1.10.3810.10 135 329 2.6E-70 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SPSF3K_RS00710 b70d623b2923ad8d7664cd4f6a6f0601 774 Pfam PF00905 Penicillin binding protein transpeptidase domain 412 679 2.8E-38 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SPSF3K_RS01255 8f75296202288226fca62ad109dbcf2e 560 Pfam PF00753 Metallo-beta-lactamase superfamily 21 169 6.9E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS01255 8f75296202288226fca62ad109dbcf2e 560 SMART SM00849 23 217 4.6E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS01255 8f75296202288226fca62ad109dbcf2e 560 Hamap MF_01491 Ribonuclease J [rnj]. 6 557 45.235 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SPSF3K_RS01255 8f75296202288226fca62ad109dbcf2e 560 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 360 409 1.5E-9 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain SPSF3K_RS01255 8f75296202288226fca62ad109dbcf2e 560 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 12 554 2.9E-196 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 SPSF3K_RS01255 8f75296202288226fca62ad109dbcf2e 560 Gene3D G3DSA:3.60.15.10 5 450 2.3E-62 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS01255 8f75296202288226fca62ad109dbcf2e 560 PIRSF PIRSF004803 3 556 3.5E-221 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SPSF3K_RS01255 8f75296202288226fca62ad109dbcf2e 560 SUPERFAMILY SSF56281 14 425 2.54E-91 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS01255 8f75296202288226fca62ad109dbcf2e 560 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 366 394 - T 29-03-2018 IPR001587 Ribonuclease J, conserved site SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1465 421.595 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 236 1461 0.0 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Pfam PF02811 PHP domain 342 701 6.7E-47 T 29-03-2018 IPR004013 PHP domain GO:0003824 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Gene3D G3DSA:3.20.20.140 577 811 1.4E-14 T 29-03-2018 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 842 1270 6.0E-90 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Gene3D G3DSA:1.10.150.280 1394 1448 0.002 T 29-03-2018 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 SUPERFAMILY SSF53098 426 892 1.94E-92 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Gene3D G3DSA:2.40.50.140 226 326 3.2E-19 T 29-03-2018 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Gene3D G3DSA:3.30.420.10 418 576 6.1E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 SMART SM00479 426 592 2.1E-44 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 SUPERFAMILY SSF89550 352 411 3.92E-5 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 423 640 3.9E-39 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 SMART SM00481 341 408 1.1E-24 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Pfam PF00929 Exonuclease 428 582 6.2E-32 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Pfam PF11490 DNA polymerase III polC-type N-terminus II 92 206 9.5E-20 T 29-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 SUPERFAMILY SSF50249 239 330 4.28E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS02580 fa16d8b6e58558cfc426834414a2aff1 1465 Pfam PF14480 DNA polymerase III polC-type N-terminus I 5 76 1.6E-16 T 29-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00255 11fd1e90cddc91f2f97f66417b99dbde 732 Gene3D G3DSA:3.30.450.40 19 176 1.3E-9 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS00255 11fd1e90cddc91f2f97f66417b99dbde 732 Pfam PF13185 GAF domain 33 165 7.3E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 SPSF3K_RS00255 11fd1e90cddc91f2f97f66417b99dbde 732 SUPERFAMILY SSF55781 16 165 4.58E-10 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS00255 11fd1e90cddc91f2f97f66417b99dbde 732 Pfam PF13556 PucR C-terminal helix-turn-helix domain 664 721 1.2E-17 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SPSF3K_RS00255 11fd1e90cddc91f2f97f66417b99dbde 732 Gene3D G3DSA:1.10.10.60 653 700 5.8E-7 T 29-03-2018 SPSF3K_RS00255 11fd1e90cddc91f2f97f66417b99dbde 732 SUPERFAMILY SSF55781 174 313 3.71E-10 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS00255 11fd1e90cddc91f2f97f66417b99dbde 732 Gene3D G3DSA:3.30.450.40 257 336 5.7E-6 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS00255 11fd1e90cddc91f2f97f66417b99dbde 732 Gene3D G3DSA:3.30.450.40 177 244 0.048 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 SMART SM00278 72 91 61.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 SMART SM00278 107 126 6.5 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 Gene3D G3DSA:2.40.50.140 1 56 3.0E-20 T 29-03-2018 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 Pfam PF01330 RuvA N terminal domain 1 61 6.1E-19 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 SUPERFAMILY SSF47781 65 133 1.75E-19 T 29-03-2018 IPR010994 RuvA domain 2-like SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 Gene3D G3DSA:1.10.150.280 57 82 0.24 T 29-03-2018 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 SUPERFAMILY SSF50249 1 62 2.23E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 195 4.3E-49 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 Gene3D G3DSA:1.10.8.10 137 195 1.6E-9 T 29-03-2018 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 Gene3D G3DSA:1.10.1670.10 112 136 0.17 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 Pfam PF07499 RuvA, C-terminal domain 152 195 2.6E-10 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 Gene3D G3DSA:1.10.150.20 83 111 4.4E-5 T 29-03-2018 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 SUPERFAMILY SSF46929 151 195 1.7E-9 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 195 29.089 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SPSF3K_RS00465 6f5948a711a995198d9f4ca17b732465 197 Pfam PF14520 Helix-hairpin-helix domain 71 127 3.3E-11 T 29-03-2018 SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 SUPERFAMILY SSF52794 3 102 2.96E-36 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 87 1.3E-30 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 545 561 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 Pfam PF02378 Phosphotransferase system, EIIC 131 403 1.1E-14 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 SUPERFAMILY SSF55804 496 641 9.55E-38 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 Gene3D G3DSA:3.40.50.2300 3 99 1.1E-37 T 29-03-2018 SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 115 461 8.1E-92 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 95 7.2E-15 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 499 641 5.1E-35 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 Gene3D G3DSA:3.40.930.10 494 643 1.9E-39 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS01110 ebee150b391f1a31b8e2da546bc3d0a2 643 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 500 627 3.2E-40 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 Pfam PF09371 Tex-like protein N-terminal domain 9 189 2.5E-61 T 29-03-2018 IPR018974 Tex-like protein, N-terminal SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 SUPERFAMILY SSF53098 305 453 7.78E-48 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 SUPERFAMILY SSF158832 2 303 2.75E-98 T 29-03-2018 SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 Gene3D G3DSA:2.40.50.140 624 710 2.9E-24 T 29-03-2018 SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 Pfam PF12836 Helix-hairpin-helix motif 475 539 2.7E-25 T 29-03-2018 SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 Gene3D G3DSA:1.10.3500.10 336 482 1.2E-38 T 29-03-2018 IPR023323 Tex-like domain SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 Pfam PF16921 Tex protein YqgF-like domain 309 435 2.4E-52 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 SMART SM00316 633 704 1.2E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 Gene3D G3DSA:1.10.150.310 483 614 3.2E-43 T 29-03-2018 SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 SMART SM00732 309 408 6.6E-37 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 SUPERFAMILY SSF47781 454 542 5.63E-25 T 29-03-2018 IPR010994 RuvA domain 2-like SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 Pfam PF00575 S1 RNA binding domain 633 703 2.0E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 SUPERFAMILY SSF47781 544 616 5.78E-17 T 29-03-2018 IPR010994 RuvA domain 2-like SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 Gene3D G3DSA:1.10.3500.10 103 335 4.5E-68 T 29-03-2018 IPR023323 Tex-like domain SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 Gene3D G3DSA:1.10.10.650 2 102 1.9E-30 T 29-03-2018 IPR023319 Tex-like protein, HTH domain SPSF3K_RS04245 66d7f77a162f789e03864a6b96e12c7d 710 SUPERFAMILY SSF50249 620 705 1.57E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS07555 baa0628ea9e32bbc6b2be79a0666b183 362 SUPERFAMILY SSF56349 60 344 9.12E-63 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPSF3K_RS07555 baa0628ea9e32bbc6b2be79a0666b183 362 Pfam PF00589 Phage integrase family 171 341 3.8E-25 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS07555 baa0628ea9e32bbc6b2be79a0666b183 362 Gene3D G3DSA:1.10.443.10 165 355 1.7E-36 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS07555 baa0628ea9e32bbc6b2be79a0666b183 362 Pfam PF14657 Arm DNA-binding domain 16 55 6.8E-7 T 29-03-2018 IPR028259 AP2-like integrase, N-terminal domain SPSF3K_RS07555 baa0628ea9e32bbc6b2be79a0666b183 362 Gene3D G3DSA:1.10.150.130 56 164 1.5E-18 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SPSF3K_RS07555 baa0628ea9e32bbc6b2be79a0666b183 362 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 61 114 1.9E-15 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPSF3K_RS05375 625e00a50395f0a4a87f6a40384ef1d6 578 Pfam PF00005 ABC transporter 350 497 2.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS05375 625e00a50395f0a4a87f6a40384ef1d6 578 SUPERFAMILY SSF52540 322 569 1.44E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05375 625e00a50395f0a4a87f6a40384ef1d6 578 Pfam PF00664 ABC transporter transmembrane region 16 280 3.2E-39 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS05375 625e00a50395f0a4a87f6a40384ef1d6 578 Gene3D G3DSA:1.20.1560.10 1 318 3.0E-66 T 29-03-2018 SPSF3K_RS05375 625e00a50395f0a4a87f6a40384ef1d6 578 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS05375 625e00a50395f0a4a87f6a40384ef1d6 578 SUPERFAMILY SSF90123 4 313 3.01E-67 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS05375 625e00a50395f0a4a87f6a40384ef1d6 578 Gene3D G3DSA:3.40.50.300 319 575 8.0E-73 T 29-03-2018 SPSF3K_RS05375 625e00a50395f0a4a87f6a40384ef1d6 578 SMART SM00382 359 551 6.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08095 5490dc3410f6880ef8d82682bf7f7efc 197 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 17 188 2.9E-39 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SPSF3K_RS08095 5490dc3410f6880ef8d82682bf7f7efc 197 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 11 193 1.0E-94 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SPSF3K_RS08095 5490dc3410f6880ef8d82682bf7f7efc 197 Gene3D G3DSA:2.60.120.10 1 197 1.5E-48 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS08095 5490dc3410f6880ef8d82682bf7f7efc 197 SUPERFAMILY SSF51182 17 192 3.06E-50 T 29-03-2018 IPR011051 RmlC-like cupin domain SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 Pfam PF00367 phosphotransferase system, EIIB 10 42 5.1E-15 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 583 595 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 SUPERFAMILY SSF55604 8 80 5.89E-21 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 Gene3D G3DSA:3.30.1360.60 3 77 1.3E-25 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 521 641 1.2E-42 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 520 644 7.6E-51 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 471 9.9E-224 T 29-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 Pfam PF02378 Phosphotransferase system, EIIC 111 413 8.4E-38 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 Gene3D G3DSA:2.70.70.10 507 668 3.6E-57 T 29-03-2018 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 108 1.0E-12 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS00550 ab182c1a13bb4e1a2a6e615845043a2c 669 SUPERFAMILY SSF51261 514 664 2.96E-52 T 29-03-2018 IPR011055 Duplicated hybrid motif SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 Gene3D G3DSA:2.40.30.10 263 380 5.4E-23 T 29-03-2018 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 Gene3D G3DSA:3.30.70.870 383 455 4.8E-12 T 29-03-2018 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 SUPERFAMILY SSF50447 249 379 1.17E-28 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 514 49.861 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.5E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 PRINTS PR00315 GTP-binding elongation factor signature 12 25 3.5E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 PRINTS PR00315 GTP-binding elongation factor signature 82 92 3.5E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 PRINTS PR00315 GTP-binding elongation factor signature 134 143 3.5E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 PRINTS PR00315 GTP-binding elongation factor signature 98 109 3.5E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 SUPERFAMILY SSF54980 383 455 6.83E-16 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 4 512 7.4E-200 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 Pfam PF16658 Class II release factor RF3, C-terminal domain 377 501 1.7E-42 T 29-03-2018 IPR032090 Peptide chain release factor 3, C-terminal SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 Pfam PF00009 Elongation factor Tu GTP binding domain 9 265 4.0E-51 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 Pfam PF03144 Elongation factor Tu domain 2 303 369 2.0E-12 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 153 9.2E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 239 261 6.5E-9 T 29-03-2018 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 120 143 6.5E-9 T 29-03-2018 SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 SUPERFAMILY SSF52540 6 265 3.49E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08710 7fb58fa886216b861d3481b07a9af38f 514 Gene3D G3DSA:3.40.50.300 3 262 1.0E-40 T 29-03-2018 SPSF3K_RS08665 2d19ae4b7b1f168b4f659f34999c24e5 342 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 340 4.4E-75 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 SPSF3K_RS08665 2d19ae4b7b1f168b4f659f34999c24e5 342 Gene3D G3DSA:1.10.8.60 146 223 1.1E-11 T 29-03-2018 SPSF3K_RS08665 2d19ae4b7b1f168b4f659f34999c24e5 342 Pfam PF06144 DNA polymerase III, delta subunit 20 192 3.3E-45 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 SPSF3K_RS08665 2d19ae4b7b1f168b4f659f34999c24e5 342 Gene3D G3DSA:1.20.272.10 224 342 1.0E-24 T 29-03-2018 SPSF3K_RS08665 2d19ae4b7b1f168b4f659f34999c24e5 342 SUPERFAMILY SSF48019 216 340 1.62E-19 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SPSF3K_RS08665 2d19ae4b7b1f168b4f659f34999c24e5 342 SUPERFAMILY SSF52540 18 210 7.97E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08665 2d19ae4b7b1f168b4f659f34999c24e5 342 Gene3D G3DSA:3.40.50.300 2 143 2.7E-13 T 29-03-2018 SPSF3K_RS00115 804217fb952d6dd2768a0fe572c295af 290 Gene3D G3DSA:1.10.4100.10 86 277 3.1E-29 T 29-03-2018 SPSF3K_RS00115 804217fb952d6dd2768a0fe572c295af 290 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 289 3.7E-109 T 29-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SPSF3K_RS00115 804217fb952d6dd2768a0fe572c295af 290 Pfam PF03313 Serine dehydratase alpha chain 19 275 4.8E-72 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit SPSF3K_RS06360 6d578b42c8f779345981c4329997237d 193 Gene3D G3DSA:3.30.60.20 140 192 7.3E-19 T 29-03-2018 SPSF3K_RS06360 6d578b42c8f779345981c4329997237d 193 SUPERFAMILY SSF57716 140 188 4.42E-16 T 29-03-2018 SPSF3K_RS06360 6d578b42c8f779345981c4329997237d 193 PIRSF PIRSF035805 1 192 1.6E-58 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SPSF3K_RS06360 6d578b42c8f779345981c4329997237d 193 Pfam PF00265 Thymidine kinase 3 184 7.4E-49 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SPSF3K_RS06360 6d578b42c8f779345981c4329997237d 193 Gene3D G3DSA:3.40.50.300 2 139 1.2E-43 T 29-03-2018 SPSF3K_RS06360 6d578b42c8f779345981c4329997237d 193 Hamap MF_00124 Thymidine kinase [tdk]. 1 187 33.675 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SPSF3K_RS06360 6d578b42c8f779345981c4329997237d 193 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 171 184 - T 29-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 SPSF3K_RS06360 6d578b42c8f779345981c4329997237d 193 SUPERFAMILY SSF52540 2 140 1.66E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05330 7a4bc9e3058202e47fe6d9a21fa66346 177 Gene3D G3DSA:1.10.530.10 24 174 3.1E-32 T 29-03-2018 SPSF3K_RS05330 7a4bc9e3058202e47fe6d9a21fa66346 177 SMART SM00047 18 174 1.1E-35 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPSF3K_RS05330 7a4bc9e3058202e47fe6d9a21fa66346 177 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 37 169 1.7E-18 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPSF3K_RS09260 5e0b9a483783d08e595b266dfed006a3 263 SUPERFAMILY SSF54506 2 263 3.49E-67 T 29-03-2018 SPSF3K_RS09260 5e0b9a483783d08e595b266dfed006a3 263 Gene3D G3DSA:3.10.310.10 1 123 1.1E-28 T 29-03-2018 SPSF3K_RS09260 5e0b9a483783d08e595b266dfed006a3 263 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 262 1.3E-42 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SPSF3K_RS09260 5e0b9a483783d08e595b266dfed006a3 263 Gene3D G3DSA:3.10.310.10 124 251 5.4E-29 T 29-03-2018 SPSF3K_RS09260 5e0b9a483783d08e595b266dfed006a3 263 PIRSF PIRSF016184 1 263 1.1E-58 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SPSF3K_RS09260 5e0b9a483783d08e595b266dfed006a3 263 Pfam PF02567 Phenazine biosynthesis-like protein 7 259 1.9E-58 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 SPSF3K_RS05140 41a0fd375ad571220bb875ddd1628a21 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SPSF3K_RS05140 41a0fd375ad571220bb875ddd1628a21 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 368 4.4E-129 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SPSF3K_RS05140 41a0fd375ad571220bb875ddd1628a21 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SPSF3K_RS05140 41a0fd375ad571220bb875ddd1628a21 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SPSF3K_RS05140 41a0fd375ad571220bb875ddd1628a21 388 Gene3D G3DSA:3.60.150.10 1 388 1.8E-126 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SPSF3K_RS05140 41a0fd375ad571220bb875ddd1628a21 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 33.601 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SPSF3K_RS05140 41a0fd375ad571220bb875ddd1628a21 388 Pfam PF01264 Chorismate synthase 1 363 2.9E-110 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SPSF3K_RS05140 41a0fd375ad571220bb875ddd1628a21 388 SUPERFAMILY SSF103263 1 386 9.55E-139 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SPSF3K_RS05140 41a0fd375ad571220bb875ddd1628a21 388 PIRSF PIRSF001456 1 380 1.4E-117 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 SPSF3K_RS08170 1d345bd21c3917d296aec24b6d0705bb 296 Gene3D G3DSA:1.10.287.890 189 268 2.8E-27 T 29-03-2018 SPSF3K_RS08170 1d345bd21c3917d296aec24b6d0705bb 296 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 7 279 1.8E-75 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SPSF3K_RS08170 1d345bd21c3917d296aec24b6d0705bb 296 Gene3D G3DSA:3.40.50.300 3 177 8.1E-53 T 29-03-2018 SPSF3K_RS08170 1d345bd21c3917d296aec24b6d0705bb 296 SUPERFAMILY SSF52540 5 74 1.48E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08170 1d345bd21c3917d296aec24b6d0705bb 296 SUPERFAMILY SSF52540 132 200 1.48E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08170 1d345bd21c3917d296aec24b6d0705bb 296 SUPERFAMILY SSF52540 245 263 1.48E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08170 1d345bd21c3917d296aec24b6d0705bb 296 SUPERFAMILY SSF52540 7 141 1.92E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08170 1d345bd21c3917d296aec24b6d0705bb 296 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 7 295 27.836 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SPSF3K_RS08170 1d345bd21c3917d296aec24b6d0705bb 296 Pfam PF01715 IPP transferase 40 271 5.1E-68 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 SUPERFAMILY SSF64484 14 1194 0.0 T 29-03-2018 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 Pfam PF05000 RNA polymerase Rpb1, domain 4 717 769 9.1E-13 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 SMART SM00663 234 513 2.3E-177 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1193 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 Pfam PF00623 RNA polymerase Rpb1, domain 2 401 484 2.5E-29 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 Pfam PF00623 RNA polymerase Rpb1, domain 2 343 390 1.0E-8 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 Pfam PF04983 RNA polymerase Rpb1, domain 3 488 673 6.8E-34 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 Gene3D G3DSA:2.40.40.20 345 487 3.1E-39 T 29-03-2018 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 13 1203 18.23 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 Gene3D G3DSA:2.40.50.100 921 1041 2.3E-36 T 29-03-2018 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 Pfam PF04998 RNA polymerase Rpb1, domain 5 780 1141 5.2E-63 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01925 3c2b3ab053900dd67df032a2d38e8f3c 1219 Pfam PF04997 RNA polymerase Rpb1, domain 1 14 341 1.0E-85 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS08105 bb868e011755b09ba1841d45bad31dca 374 SUPERFAMILY SSF54373 217 305 7.19E-10 T 29-03-2018 SPSF3K_RS08105 bb868e011755b09ba1841d45bad31dca 374 Gene3D G3DSA:3.50.50.60 2 362 1.9E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS08105 bb868e011755b09ba1841d45bad31dca 374 SUPERFAMILY SSF51905 307 364 1.17E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS08105 bb868e011755b09ba1841d45bad31dca 374 SUPERFAMILY SSF51905 5 216 1.17E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS08105 bb868e011755b09ba1841d45bad31dca 374 Pfam PF01266 FAD dependent oxidoreductase 7 346 9.6E-44 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SPSF3K_RS10430 7bc8942d1def128d7936b2015d3c6ad9 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 29-03-2018 IPR018038 Ribosomal protein L30, conserved site SPSF3K_RS10430 7bc8942d1def128d7936b2015d3c6ad9 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 18.499 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10430 7bc8942d1def128d7936b2015d3c6ad9 60 Gene3D G3DSA:3.30.1390.20 4 58 6.3E-23 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SPSF3K_RS10430 7bc8942d1def128d7936b2015d3c6ad9 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 3.6E-27 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10430 7bc8942d1def128d7936b2015d3c6ad9 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 5.8E-19 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SPSF3K_RS10430 7bc8942d1def128d7936b2015d3c6ad9 60 PIRSF PIRSF002211 1 60 1.5E-27 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10430 7bc8942d1def128d7936b2015d3c6ad9 60 SUPERFAMILY SSF55129 1 59 9.81E-20 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SPSF3K_RS00925 761def4c4dd5bfcf84888b95ee2dc786 301 Gene3D G3DSA:3.90.550.10 1 281 1.0E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS00925 761def4c4dd5bfcf84888b95ee2dc786 301 Pfam PF00483 Nucleotidyl transferase 6 266 4.3E-32 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SPSF3K_RS00925 761def4c4dd5bfcf84888b95ee2dc786 301 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 268 2.4E-110 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 SPSF3K_RS00925 761def4c4dd5bfcf84888b95ee2dc786 301 SUPERFAMILY SSF53448 1 272 2.25E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 94 105 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 PIRSF PIRSF039102 1 345 6.1E-102 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 SUPERFAMILY SSF56059 127 335 3.54E-55 T 29-03-2018 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 Gene3D G3DSA:3.30.1490.20 129 200 3.5E-17 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 Pfam PF01820 D-ala D-ala ligase N-terminus 6 116 1.1E-25 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 SUPERFAMILY SSF52440 3 126 8.15E-31 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 Gene3D G3DSA:3.30.470.20 201 346 7.4E-36 T 29-03-2018 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 Gene3D G3DSA:3.40.50.20 1 128 1.5E-36 T 29-03-2018 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 279 307 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 337 38.278 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 336 5.7E-99 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08730 c562647051fbc2855801420ee9ee9b16 348 Pfam PF07478 D-ala D-ala ligase C-terminus 135 333 1.1E-69 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS05740 0ee45646dcbb25166d7b6d3c7db4c000 187 Pfam PF01923 Cobalamin adenosyltransferase 3 168 1.0E-48 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SPSF3K_RS05740 0ee45646dcbb25166d7b6d3c7db4c000 187 Gene3D G3DSA:1.20.1200.10 12 187 4.0E-47 T 29-03-2018 SPSF3K_RS05740 0ee45646dcbb25166d7b6d3c7db4c000 187 SUPERFAMILY SSF89028 1 180 1.06E-50 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SPSF3K_RS05740 0ee45646dcbb25166d7b6d3c7db4c000 187 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 179 5.2E-53 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SPSF3K_RS05740 0ee45646dcbb25166d7b6d3c7db4c000 187 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 181 5.0E-31 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 195 2.0E-41 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 5 89 1.8E-29 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 3.8E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 3.8E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 3.8E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 PRINTS PR01703 Manganese superoxide dismutase signature 161 173 3.8E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 3.8E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 163 170 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 SUPERFAMILY SSF46609 1 90 7.46E-33 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 PIRSF PIRSF000349 1 202 9.0E-80 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 SUPERFAMILY SSF54719 91 200 1.14E-46 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 SPSF3K_RS08660 4de4b335ec62c28f9bc6986a639dc3dd 202 Gene3D G3DSA:1.10.287.990 20 89 1.1E-26 T 29-03-2018 SPSF3K_RS09120 758cc4efee1e29c99641d3cea6b01fd2 284 Pfam PF01844 HNH endonuclease 216 265 7.0E-12 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SPSF3K_RS09120 758cc4efee1e29c99641d3cea6b01fd2 284 Gene3D G3DSA:3.40.1800.10 186 278 2.0E-14 T 29-03-2018 SPSF3K_RS09120 758cc4efee1e29c99641d3cea6b01fd2 284 SMART SM00507 203 261 4.9E-5 T 29-03-2018 IPR003615 HNH nuclease SPSF3K_RS09870 2eeaf1a3b8872d38bcc8c9dbbb523a6f 85 Gene3D G3DSA:1.10.287.540 3 55 5.6E-24 T 29-03-2018 SPSF3K_RS09870 2eeaf1a3b8872d38bcc8c9dbbb523a6f 85 Pfam PF05979 Bacterial protein of unknown function (DUF896) 4 67 3.7E-29 T 29-03-2018 IPR009242 Protein of unknown function DUF896 SPSF3K_RS09870 2eeaf1a3b8872d38bcc8c9dbbb523a6f 85 SUPERFAMILY SSF158221 2 41 9.94E-13 T 29-03-2018 SPSF3K_RS09870 2eeaf1a3b8872d38bcc8c9dbbb523a6f 85 Hamap MF_01103 UPF0291 protein . 1 59 16.296 T 29-03-2018 IPR009242 Protein of unknown function DUF896 SPSF3K_RS06650 697765653774532f4f48d3b96665ee87 124 Gene3D G3DSA:2.30.110.10 1 124 3.6E-10 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SPSF3K_RS06650 697765653774532f4f48d3b96665ee87 124 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 3 96 2.5E-6 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SPSF3K_RS06650 697765653774532f4f48d3b96665ee87 124 SUPERFAMILY SSF50475 1 121 7.85E-25 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SPSF3K_RS06900 4b0dc98b6bf387415a8632ec024693d8 149 Pfam PF02566 OsmC-like protein 37 139 1.8E-20 T 29-03-2018 IPR003718 OsmC/Ohr family SPSF3K_RS06900 4b0dc98b6bf387415a8632ec024693d8 149 SUPERFAMILY SSF82784 3 139 5.63E-37 T 29-03-2018 IPR003718 OsmC/Ohr family SPSF3K_RS06900 4b0dc98b6bf387415a8632ec024693d8 149 Gene3D G3DSA:3.30.300.20 1 147 2.2E-28 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS02385 ce427c19c8eb46eeb2d6fe61aaea4fa7 420 Pfam PF03390 2-hydroxycarboxylate transporter family 6 414 1.2E-132 T 29-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 SPSF3K_RS02385 ce427c19c8eb46eeb2d6fe61aaea4fa7 420 PIRSF PIRSF005348 1 420 2.0E-139 T 29-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 SPSF3K_RS02795 24703a9213ea6334805f235340c6c9e9 234 SUPERFAMILY SSF52317 38 232 6.21E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS02795 24703a9213ea6334805f235340c6c9e9 234 Pfam PF07722 Peptidase C26 4 213 2.5E-63 T 29-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 SPSF3K_RS02795 24703a9213ea6334805f235340c6c9e9 234 Gene3D G3DSA:3.40.50.880 1 234 1.8E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 167 1.2E-26 T 29-03-2018 IPR001453 MoaB/Mog domain SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 SMART SM00852 4 171 3.3E-36 T 29-03-2018 IPR001453 MoaB/Mog domain SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 416 1.0E-113 T 29-03-2018 IPR008135 Competence-induced protein CinA SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 271 415 1.5E-30 T 29-03-2018 IPR008136 CinA, C-terminal SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 SUPERFAMILY SSF142433 259 417 4.97E-43 T 29-03-2018 IPR008136 CinA, C-terminal SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 Gene3D G3DSA:3.40.980.10 1 172 3.1E-38 T 29-03-2018 IPR001453 MoaB/Mog domain SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 423 149.906 T 29-03-2018 IPR008135 Competence-induced protein CinA SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 Pfam PF00994 Probable molybdopterin binding domain 5 169 6.5E-31 T 29-03-2018 IPR001453 MoaB/Mog domain SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 Gene3D G3DSA:3.90.950.20 257 421 5.6E-46 T 29-03-2018 SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 SUPERFAMILY SSF53218 1 201 2.49E-38 T 29-03-2018 IPR001453 MoaB/Mog domain SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 PIRSF PIRSF006728 1 422 4.2E-138 T 29-03-2018 IPR008135 Competence-induced protein CinA SPSF3K_RS00475 108f8c2c3e0b99d2c0670d2d56b0e5d1 423 Pfam PF02464 Competence-damaged protein 263 416 1.8E-44 T 29-03-2018 IPR008136 CinA, C-terminal SPSF3K_RS03680 ce3ef3e9356a17d1cfdad3ced4a55ed1 391 SUPERFAMILY SSF55021 307 389 1.29E-13 T 29-03-2018 SPSF3K_RS03680 ce3ef3e9356a17d1cfdad3ced4a55ed1 391 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 139 166 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SPSF3K_RS03680 ce3ef3e9356a17d1cfdad3ced4a55ed1 391 SUPERFAMILY SSF51735 84 274 7.33E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS03680 ce3ef3e9356a17d1cfdad3ced4a55ed1 391 Gene3D G3DSA:3.40.50.720 98 275 6.9E-37 T 29-03-2018 SPSF3K_RS03680 ce3ef3e9356a17d1cfdad3ced4a55ed1 391 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 125 273 2.5E-39 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SPSF3K_RS03680 ce3ef3e9356a17d1cfdad3ced4a55ed1 391 Gene3D G3DSA:3.30.70.260 307 389 1.1E-12 T 29-03-2018 SPSF3K_RS03680 ce3ef3e9356a17d1cfdad3ced4a55ed1 391 SUPERFAMILY SSF52283 29 110 7.18E-18 T 29-03-2018 SPSF3K_RS03680 ce3ef3e9356a17d1cfdad3ced4a55ed1 391 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 50 305 3.9E-16 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SPSF3K_RS03680 ce3ef3e9356a17d1cfdad3ced4a55ed1 391 Gene3D G3DSA:3.40.50.720 30 97 1.8E-15 T 29-03-2018 SPSF3K_RS02335 41c6ab79d9e3b0e4710a2d5b232c1e51 105 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 102 7.1E-13 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core SPSF3K_RS02335 41c6ab79d9e3b0e4710a2d5b232c1e51 105 SUPERFAMILY SSF101386 1 103 2.78E-28 T 29-03-2018 SPSF3K_RS02335 41c6ab79d9e3b0e4710a2d5b232c1e51 105 Gene3D G3DSA:1.10.287.1080 1 105 1.9E-18 T 29-03-2018 SPSF3K_RS02335 41c6ab79d9e3b0e4710a2d5b232c1e51 105 PIRSF PIRSF036521 1 105 2.3E-53 T 29-03-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 Gene3D G3DSA:3.90.110.10 147 321 3.2E-48 T 29-03-2018 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 12 309 3.4E-122 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 PIRSF PIRSF000102 4 323 2.1E-103 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 SUPERFAMILY SSF51735 4 148 6.4E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 6.9E-48 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 PRINTS PR00086 L-lactate dehydrogenase signature 9 33 6.9E-48 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 PRINTS PR00086 L-lactate dehydrogenase signature 34 58 6.9E-48 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 6.9E-48 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 6.9E-48 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 29-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 SUPERFAMILY SSF56327 147 315 7.21E-53 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 7 316 44.23 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 317 3.3E-39 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 Gene3D G3DSA:3.40.50.720 8 146 2.3E-31 T 29-03-2018 SPSF3K_RS06410 ffb23015d3cc216c8c30074d70c02792 327 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 9 146 1.8E-46 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 SPSF3K_RS07990 4fbc88b688e0e6180831f90ddb536a2d 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 4 320 2.4E-97 T 29-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 SPSF3K_RS07990 4fbc88b688e0e6180831f90ddb536a2d 329 SUPERFAMILY SSF82649 242 328 7.85E-25 T 29-03-2018 SPSF3K_RS07990 4fbc88b688e0e6180831f90ddb536a2d 329 SUPERFAMILY SSF55681 1 241 1.21E-78 T 29-03-2018 SPSF3K_RS07990 4fbc88b688e0e6180831f90ddb536a2d 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 244 327 2.3E-25 T 29-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 SPSF3K_RS07990 4fbc88b688e0e6180831f90ddb536a2d 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 45 154 6.9E-9 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SPSF3K_RS07990 4fbc88b688e0e6180831f90ddb536a2d 329 Gene3D G3DSA:3.30.930.10 1 246 6.7E-70 T 29-03-2018 SPSF3K_RS07990 4fbc88b688e0e6180831f90ddb536a2d 329 Gene3D G3DSA:3.30.390.50 247 329 6.1E-22 T 29-03-2018 SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 PIRSF PIRSF000097 1 279 6.8E-74 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 133 150 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 Gene3D G3DSA:3.20.20.100 1 274 1.4E-80 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 Pfam PF00248 Aldo/keto reductase family 16 267 2.2E-44 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 SUPERFAMILY SSF51430 1 268 1.15E-81 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 PRINTS PR00069 Aldo-keto reductase signature 204 228 1.8E-40 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 PRINTS PR00069 Aldo-keto reductase signature 133 150 1.8E-40 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 PRINTS PR00069 Aldo-keto reductase signature 35 59 1.8E-40 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 PRINTS PR00069 Aldo-keto reductase signature 91 109 1.8E-40 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS07895 74aaf469240eb54a79ad7d98fc290757 284 PRINTS PR00069 Aldo-keto reductase signature 167 196 1.8E-40 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS02060 c2f0110a6f75e740731a7842634a83d2 501 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 10 57 1.2E-8 T 29-03-2018 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain SPSF3K_RS02060 c2f0110a6f75e740731a7842634a83d2 501 Gene3D G3DSA:1.10.10.10 4 84 0.12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02060 c2f0110a6f75e740731a7842634a83d2 501 Gene3D G3DSA:1.10.10.10 91 143 1.7E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02060 c2f0110a6f75e740731a7842634a83d2 501 Pfam PF05043 Mga helix-turn-helix domain 78 161 3.6E-17 T 29-03-2018 IPR007737 Mga helix-turn-helix domain SPSF3K_RS02060 c2f0110a6f75e740731a7842634a83d2 501 Pfam PF08270 M protein trans-acting positive regulator (MGA) PRD domain 179 391 1.9E-18 T 29-03-2018 IPR013236 M protein trans-acting positive regulator (MGA), PRD domain SPSF3K_RS07905 558403e839c3d2b33b03be832d79db72 154 SUPERFAMILY SSF55729 1 150 3.04E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS07905 558403e839c3d2b33b03be832d79db72 154 Gene3D G3DSA:3.40.630.30 1 151 2.3E-23 T 29-03-2018 SPSF3K_RS07905 558403e839c3d2b33b03be832d79db72 154 Pfam PF00583 Acetyltransferase (GNAT) family 37 138 1.4E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS01415 8568ee9e0be01b62bcb65aac9c2fec71 294 Hamap MF_00397 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [citG]. 1 294 141.379 T 29-03-2018 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 SPSF3K_RS01415 8568ee9e0be01b62bcb65aac9c2fec71 294 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 11 287 1.7E-67 T 29-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 SPSF3K_RS01415 8568ee9e0be01b62bcb65aac9c2fec71 294 TIGRFAM TIGR03125 citrate_citG: triphosphoribosyl-dephospho-CoA synthase CitG 10 289 2.1E-95 T 29-03-2018 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 Gene3D G3DSA:3.40.50.300 1 209 2.6E-58 T 29-03-2018 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 SUPERFAMILY SSF52540 2 197 4.86E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 191 9.8E-47 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 PRINTS PR00988 Uridine kinase signature 5 22 1.4E-39 T 29-03-2018 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 PRINTS PR00988 Uridine kinase signature 172 185 1.4E-39 T 29-03-2018 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 PRINTS PR00988 Uridine kinase signature 150 161 1.4E-39 T 29-03-2018 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 PRINTS PR00988 Uridine kinase signature 80 95 1.4E-39 T 29-03-2018 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 PRINTS PR00988 Uridine kinase signature 35 46 1.4E-39 T 29-03-2018 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 PRINTS PR00988 Uridine kinase signature 136 146 1.4E-39 T 29-03-2018 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 TIGRFAM TIGR00235 udk: uridine kinase 3 205 5.4E-87 T 29-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 SPSF3K_RS08515 c648b6ea0a0480aa3d5ffb5eae24c116 209 Hamap MF_00551 Uridine kinase [udk]. 2 206 42.54 T 29-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 SPSF3K_RS00485 48a2b10563fa63936053bca0355c53a9 132 Gene3D G3DSA:3.40.30.10 1 131 3.4E-33 T 29-03-2018 SPSF3K_RS00485 48a2b10563fa63936053bca0355c53a9 132 SUPERFAMILY SSF52833 1 125 1.55E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS00485 48a2b10563fa63936053bca0355c53a9 132 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 1.0E-32 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR SPSF3K_RS00485 48a2b10563fa63936053bca0355c53a9 132 Pfam PF03960 ArsC family 7 113 2.2E-19 T 29-03-2018 IPR006660 Arsenate reductase-like SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 SUPERFAMILY SSF47831 24 145 3.27E-34 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 PIRSF PIRSF000732 1 574 2.5E-211 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 Gene3D G3DSA:3.50.30.10 138 256 2.2E-28 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 SUPERFAMILY SSF52009 127 244 4.71E-36 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 186 197 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 451 469 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 504 516 1.7E-32 T 29-03-2018 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 468 483 1.7E-32 T 29-03-2018 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 295 314 1.7E-32 T 29-03-2018 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 451 466 1.7E-32 T 29-03-2018 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 227 9.5E-22 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 544 3.8E-128 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 SUPERFAMILY SSF51621 251 553 5.5E-109 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 Gene3D G3DSA:1.10.274.10 26 137 2.5E-36 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 569 1.6E-227 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 128 2.6E-30 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SPSF3K_RS08535 7f5d9697beac1bbe4a8406c80d094168 574 Gene3D G3DSA:3.20.20.60 257 574 1.6E-98 T 29-03-2018 SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 Gene3D G3DSA:1.20.1250.20 8 215 1.3E-30 T 29-03-2018 SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 Pfam PF07690 Major Facilitator Superfamily 23 424 6.5E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 Gene3D G3DSA:1.20.1250.20 275 494 3.6E-33 T 29-03-2018 SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 SUPERFAMILY SSF103473 264 436 3.27E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 SUPERFAMILY SSF103473 465 489 3.27E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 SUPERFAMILY SSF103473 14 212 3.27E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 3.9E-7 T 29-03-2018 SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 3.9E-7 T 29-03-2018 SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 135 3.9E-7 T 29-03-2018 SPSF3K_RS01145 1646d1b07228f0a76beea2928af1be5d 499 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 452 5.0E-87 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 SPSF3K_RS04625 80356955fcfcadaa4075e3c3805dd5d2 135 SUPERFAMILY SSF53062 3 111 3.53E-34 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPSF3K_RS04625 80356955fcfcadaa4075e3c3805dd5d2 135 Pfam PF03610 PTS system fructose IIA component 5 103 6.8E-22 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPSF3K_RS04625 80356955fcfcadaa4075e3c3805dd5d2 135 Gene3D G3DSA:3.40.50.510 2 124 3.4E-28 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 SUPERFAMILY SSF51905 1 313 7.33E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 Gene3D G3DSA:3.50.50.60 1 137 1.6E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 3.6E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 Gene3D G3DSA:3.40.50.720 149 319 3.4E-20 T 29-03-2018 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 9.4E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 9.4E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 9.4E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 9.4E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 9.4E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 6.8E-18 T 29-03-2018 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 6.8E-18 T 29-03-2018 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.8E-18 T 29-03-2018 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 6.8E-18 T 29-03-2018 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 6.8E-18 T 29-03-2018 SPSF3K_RS05300 ac26d1d1fab65e5a68df4ca59f29b2f0 330 Hamap MF_01685 Ferredoxin--NADP reductase. 5 328 41.098 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 SPSF3K_RS02940 6b08eacd0a516424a0d55cd605a9f58e 235 Pfam PF04172 LrgB-like family 19 231 2.8E-64 T 29-03-2018 IPR007300 CidB/LrgB family SPSF3K_RS02940 6b08eacd0a516424a0d55cd605a9f58e 235 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 6 235 27.933 T 29-03-2018 IPR024891 Antiholin-like protein LrgB SPSF3K_RS08965 2d50a40690f1b1930afdfb72c7a35f98 176 PIRSF PIRSF005900 8 175 1.2E-40 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPSF3K_RS08965 2d50a40690f1b1930afdfb72c7a35f98 176 ProSitePatterns PS00818 Dps protein family signature 1. 50 66 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 SPSF3K_RS08965 2d50a40690f1b1930afdfb72c7a35f98 176 Gene3D G3DSA:1.20.1260.10 1 176 7.8E-41 T 29-03-2018 IPR012347 Ferritin-related SPSF3K_RS08965 2d50a40690f1b1930afdfb72c7a35f98 176 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 147 165 2.7E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPSF3K_RS08965 2d50a40690f1b1930afdfb72c7a35f98 176 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 50 66 2.7E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPSF3K_RS08965 2d50a40690f1b1930afdfb72c7a35f98 176 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 74 90 2.7E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPSF3K_RS08965 2d50a40690f1b1930afdfb72c7a35f98 176 Pfam PF00210 Ferritin-like domain 31 171 1.4E-25 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SPSF3K_RS08965 2d50a40690f1b1930afdfb72c7a35f98 176 SUPERFAMILY SSF47240 26 169 2.44E-37 T 29-03-2018 IPR009078 Ferritin-like superfamily SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 Gene3D G3DSA:3.40.50.1980 200 318 5.8E-37 T 29-03-2018 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 SUPERFAMILY SSF53807 32 315 1.13E-80 T 29-03-2018 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 SUPERFAMILY SSF50814 328 515 7.22E-78 T 29-03-2018 IPR012674 Calycin SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 333 515 2.2E-81 T 29-03-2018 IPR015304 ZinT domain GO:0008270 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 Pfam PF01297 Zinc-uptake complex component A periplasmic 35 316 1.5E-76 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 Gene3D G3DSA:2.40.128.20 325 515 6.0E-66 T 29-03-2018 IPR012674 Calycin SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 PRINTS PR00691 Adhesin B signature 57 75 1.2E-10 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 PRINTS PR00691 Adhesin B signature 254 271 1.2E-10 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 PRINTS PR00691 Adhesin B signature 32 53 1.2E-10 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 PRINTS PR00691 Adhesin B signature 298 316 1.2E-10 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 PRINTS PR00691 Adhesin B signature 76 95 1.2E-10 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 PRINTS PR00690 Adhesin family signature 63 76 1.5E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 PRINTS PR00690 Adhesin family signature 258 276 1.5E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 PRINTS PR00690 Adhesin family signature 32 50 1.5E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 PRINTS PR00690 Adhesin family signature 205 226 1.5E-10 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS04575 221f2e58be3c2fe335d27a6f0b3350f4 515 Gene3D G3DSA:3.40.50.1980 32 199 1.2E-53 T 29-03-2018 SPSF3K_RS05080 0b6e3e1cac01e9d0db8d6f0bd4ba6313 747 SUPERFAMILY SSF53187 551 744 3.77E-52 T 29-03-2018 SPSF3K_RS05080 0b6e3e1cac01e9d0db8d6f0bd4ba6313 747 Gene3D G3DSA:3.40.630.40 548 747 8.3E-57 T 29-03-2018 SPSF3K_RS05080 0b6e3e1cac01e9d0db8d6f0bd4ba6313 747 Pfam PF08481 GBS Bsp-like repeat 444 531 2.1E-18 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS05080 0b6e3e1cac01e9d0db8d6f0bd4ba6313 747 Pfam PF08481 GBS Bsp-like repeat 168 224 9.9E-10 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS05080 0b6e3e1cac01e9d0db8d6f0bd4ba6313 747 Pfam PF08481 GBS Bsp-like repeat 338 426 4.6E-23 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS05080 0b6e3e1cac01e9d0db8d6f0bd4ba6313 747 Pfam PF08481 GBS Bsp-like repeat 237 324 4.0E-27 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS05080 0b6e3e1cac01e9d0db8d6f0bd4ba6313 747 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 553 739 2.0E-50 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SPSF3K_RS05080 0b6e3e1cac01e9d0db8d6f0bd4ba6313 747 SMART SM00646 611 739 3.1E-37 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 SPSF3K_RS06095 1062b5747f0ef6d66cb37c91b81ee721 186 SUPERFAMILY SSF55620 2 184 8.89E-75 T 29-03-2018 SPSF3K_RS06095 1062b5747f0ef6d66cb37c91b81ee721 186 Gene3D G3DSA:3.30.1130.10 53 186 1.7E-58 T 29-03-2018 SPSF3K_RS06095 1062b5747f0ef6d66cb37c91b81ee721 186 Pfam PF01227 GTP cyclohydrolase I 7 183 3.2E-77 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SPSF3K_RS06095 1062b5747f0ef6d66cb37c91b81ee721 186 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 2 184 41.05 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SPSF3K_RS06095 1062b5747f0ef6d66cb37c91b81ee721 186 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 7 184 1.7E-72 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SPSF3K_RS06095 1062b5747f0ef6d66cb37c91b81ee721 186 Gene3D G3DSA:1.10.286.10 4 51 1.0E-21 T 29-03-2018 SPSF3K_RS06095 1062b5747f0ef6d66cb37c91b81ee721 186 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 111 121 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 SPSF3K_RS10095 caf03341187059619ecb94a9e7af6cf0 306 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 302 2.5E-42 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain SPSF3K_RS10095 caf03341187059619ecb94a9e7af6cf0 306 SUPERFAMILY SSF55048 126 195 3.4E-17 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SPSF3K_RS10095 caf03341187059619ecb94a9e7af6cf0 306 Gene3D G3DSA:3.40.366.10 178 306 3.8E-23 T 29-03-2018 SPSF3K_RS10095 caf03341187059619ecb94a9e7af6cf0 306 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 288 1.7E-106 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SPSF3K_RS10095 caf03341187059619ecb94a9e7af6cf0 306 PIRSF PIRSF000446 1 306 3.5E-108 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SPSF3K_RS10095 caf03341187059619ecb94a9e7af6cf0 306 Pfam PF00698 Acyl transferase domain 6 284 7.1E-37 T 29-03-2018 IPR014043 Acyl transferase SPSF3K_RS10095 caf03341187059619ecb94a9e7af6cf0 306 Gene3D G3DSA:3.40.366.10 1 177 4.3E-54 T 29-03-2018 SPSF3K_RS10095 caf03341187059619ecb94a9e7af6cf0 306 SUPERFAMILY SSF52151 4 120 1.62E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SPSF3K_RS10095 caf03341187059619ecb94a9e7af6cf0 306 SUPERFAMILY SSF52151 188 304 1.62E-74 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SPSF3K_RS06955 66b78cbbac705099935fc2cfa6f4e8bc 528 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 56 528 1.2E-90 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 SPSF3K_RS06955 66b78cbbac705099935fc2cfa6f4e8bc 528 Gene3D G3DSA:3.30.870.10 129 330 2.6E-31 T 29-03-2018 SPSF3K_RS06955 66b78cbbac705099935fc2cfa6f4e8bc 528 SUPERFAMILY SSF56024 338 513 1.53E-36 T 29-03-2018 SPSF3K_RS06955 66b78cbbac705099935fc2cfa6f4e8bc 528 SUPERFAMILY SSF56024 145 357 1.88E-42 T 29-03-2018 SPSF3K_RS06955 66b78cbbac705099935fc2cfa6f4e8bc 528 Gene3D G3DSA:3.30.870.10 360 509 9.9E-25 T 29-03-2018 SPSF3K_RS06955 66b78cbbac705099935fc2cfa6f4e8bc 528 SMART SM00155 441 468 9.1E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SPSF3K_RS06955 66b78cbbac705099935fc2cfa6f4e8bc 528 SMART SM00155 264 291 1.2E-6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 SPSF3K_RS06955 66b78cbbac705099935fc2cfa6f4e8bc 528 Pfam PF13091 PLD-like domain 182 324 4.5E-10 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SPSF3K_RS06955 66b78cbbac705099935fc2cfa6f4e8bc 528 Pfam PF13091 PLD-like domain 369 494 6.5E-21 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 SPSF3K_RS03415 0480ba7b7ae4499a8b9d044c7471499e 96 SUPERFAMILY SSF88659 42 94 1.87E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS03415 0480ba7b7ae4499a8b9d044c7471499e 96 Gene3D G3DSA:1.10.10.10 23 96 3.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 SUPERFAMILY SSF52540 7 237 8.38E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 Gene3D G3DSA:3.40.50.300 1 288 2.0E-53 T 29-03-2018 SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 Gene3D G3DSA:3.40.50.300 307 538 1.4E-38 T 29-03-2018 SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 Pfam PF00005 ABC transporter 336 467 5.2E-12 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 Pfam PF00005 ABC transporter 18 184 9.4E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 SUPERFAMILY SSF52540 294 514 1.95E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 Pfam PF12848 ABC transporter 224 304 5.8E-21 T 29-03-2018 IPR032781 ABC-transporter extension domain SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 SMART SM00382 26 228 4.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00040 91f0b83f271be705d9e08cd23c840749 539 SMART SM00382 344 512 0.9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 SMART SM00436 132 227 3.9E-41 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 Gene3D G3DSA:3.30.65.10 615 674 2.8E-12 T 29-03-2018 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 690 3.3E-180 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 SUPERFAMILY SSF57783 632 665 2.72E-6 T 29-03-2018 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 SMART SM00493 2 129 3.4E-31 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 SUPERFAMILY SSF56712 3 605 6.54E-165 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 Pfam PF01751 Toprim domain 4 140 2.3E-18 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 400 416 1.5E-23 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 319 328 1.5E-23 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 197 215 1.5E-23 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 1.5E-23 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 518 532 1.5E-23 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 Gene3D G3DSA:1.10.460.10 166 349 2.3E-31 T 29-03-2018 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 Gene3D G3DSA:1.10.460.10 479 614 1.4E-19 T 29-03-2018 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 Gene3D G3DSA:3.40.50.140 2 160 1.0E-40 T 29-03-2018 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 Gene3D G3DSA:2.70.20.10 356 478 1.9E-22 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 314 328 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 SMART SM00437 277 555 8.3E-107 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 630 659 5.7E-11 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 SPSF3K_RS05800 9175c681bba316ff026fc28087c8a574 714 Pfam PF01131 DNA topoisomerase 163 591 2.0E-104 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05575 a709a8cf3138202e18f65c77c139c698 1283 Gene3D G3DSA:3.40.1360.10 193 354 2.6E-20 T 29-03-2018 SPSF3K_RS05575 a709a8cf3138202e18f65c77c139c698 1283 Gene3D G3DSA:3.90.182.10 421 940 6.7E-14 T 29-03-2018 SPSF3K_RS05575 a709a8cf3138202e18f65c77c139c698 1283 Gene3D G3DSA:3.90.580.10 1 134 3.5E-12 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SPSF3K_RS05575 a709a8cf3138202e18f65c77c139c698 1283 Pfam PF13155 Toprim-like 212 336 1.9E-8 T 29-03-2018 SPSF3K_RS05575 a709a8cf3138202e18f65c77c139c698 1283 Pfam PF13154 Protein of unknown function (DUF3991) 119 179 5.4E-6 T 29-03-2018 IPR025054 Domain of unknown function DUF3991 SPSF3K_RS05575 a709a8cf3138202e18f65c77c139c698 1283 SUPERFAMILY SSF57783 3 85 2.89E-8 T 29-03-2018 SPSF3K_RS07625 e0aef3ca74ef592a294442b37085599e 288 Gene3D G3DSA:3.40.190.10 4 156 1.1E-32 T 29-03-2018 SPSF3K_RS07625 e0aef3ca74ef592a294442b37085599e 288 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 62 75 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SPSF3K_RS07625 e0aef3ca74ef592a294442b37085599e 288 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 265 7.0E-52 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS07625 e0aef3ca74ef592a294442b37085599e 288 Gene3D G3DSA:3.40.190.10 157 270 7.1E-14 T 29-03-2018 SPSF3K_RS07625 e0aef3ca74ef592a294442b37085599e 288 SUPERFAMILY SSF53850 1 266 3.37E-55 T 29-03-2018 SPSF3K_RS07625 e0aef3ca74ef592a294442b37085599e 288 SMART SM00062 39 267 4.6E-50 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS03065 504deddf21af62da43a5675ebd658efe 499 Gene3D G3DSA:1.10.3720.10 1 485 5.4E-38 T 29-03-2018 SPSF3K_RS03065 504deddf21af62da43a5675ebd658efe 499 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 299 492 1.7E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS03065 504deddf21af62da43a5675ebd658efe 499 SUPERFAMILY SSF161098 280 475 1.53E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 178 344 7.7E-27 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 125 2.0E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 2.2E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 Pfam PF01926 50S ribosome-binding GTPase 177 295 1.5E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 Gene3D G3DSA:3.30.300.20 358 434 1.2E-34 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 SUPERFAMILY SSF52540 138 435 1.67E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 PIRSF PIRSF006485 2 436 2.0E-169 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 Hamap MF_00195 GTPase Der [der]. 3 436 39.993 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 Gene3D G3DSA:1.20.120.430 71 241 1.1E-41 T 29-03-2018 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 7.1E-172 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 Gene3D G3DSA:1.20.120.430 242 357 1.8E-16 T 29-03-2018 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 Gene3D G3DSA:1.20.120.430 3 70 6.1E-19 T 29-03-2018 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 1.1E-32 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 6.7E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 177 197 6.7E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS03260 5df84f3d6d792c2c587a967f70d934aa 436 SUPERFAMILY SSF52540 4 164 1.03E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 495 1.0E-221 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 SUPERFAMILY SSF53067 5 255 6.05E-96 T 29-03-2018 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 Gene3D G3DSA:3.30.420.40 1 249 1.2E-87 T 29-03-2018 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 451 1.9E-57 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 253 4.2E-85 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 Gene3D G3DSA:3.30.420.40 250 503 5.1E-72 T 29-03-2018 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 Hamap MF_00186 Glycerol kinase [glpK]. 4 498 56.449 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 SUPERFAMILY SSF53067 256 494 1.49E-79 T 29-03-2018 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 PIRSF PIRSF000538 4 502 2.4E-171 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SPSF3K_RS09855 ebaf854c551ec9d9a32d7f7c5450eff2 503 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 170 180 9.8E-41 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 188 197 9.8E-41 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 722 737 9.8E-41 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 372 388 9.8E-41 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 202 218 9.8E-41 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 154 166 9.8E-41 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 507 523 9.8E-41 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 184 501 8.2E-83 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 Pfam PF09168 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal 1 145 5.0E-40 T 29-03-2018 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 530 751 5.2E-28 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 SUPERFAMILY SSF53474 149 549 1.15E-94 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 Hamap MF_00698 Xaa-Pro dipeptidyl-peptidase [pepX]. 1 757 36.035 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 SUPERFAMILY SSF49785 551 756 8.08E-73 T 29-03-2018 IPR008979 Galactose-binding domain-like SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 SMART SM00940 1 145 1.9E-56 T 29-03-2018 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 Gene3D G3DSA:2.60.120.260 550 757 5.8E-27 T 29-03-2018 IPR008979 Galactose-binding domain-like SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 SUPERFAMILY SSF81761 1 146 2.75E-37 T 29-03-2018 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 SMART SM00939 515 754 1.3E-54 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SPSF3K_RS01530 877803680f152e62cd6e7abbe8d45cb8 757 Gene3D G3DSA:3.40.50.1820 168 549 2.2E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 SUPERFAMILY SSF51419 13 241 2.33E-62 T 29-03-2018 IPR029066 PLP-binding barrel SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 Gene3D G3DSA:2.40.37.10 226 367 1.9E-51 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 SMART SM01005 242 367 1.2E-64 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 SUPERFAMILY SSF50621 237 367 8.72E-48 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 Hamap MF_01201 Alanine racemase. 6 367 34.808 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 PRINTS PR00992 Alanine racemase signature 258 273 9.6E-68 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 PRINTS PR00992 Alanine racemase signature 127 139 9.6E-68 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 PRINTS PR00992 Alanine racemase signature 275 290 9.6E-68 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 PRINTS PR00992 Alanine racemase signature 201 228 9.6E-68 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 PRINTS PR00992 Alanine racemase signature 67 85 9.6E-68 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 PRINTS PR00992 Alanine racemase signature 295 312 9.6E-68 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 PRINTS PR00992 Alanine racemase signature 349 362 9.6E-68 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 PRINTS PR00992 Alanine racemase signature 32 48 9.6E-68 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 PRINTS PR00992 Alanine racemase signature 161 172 9.6E-68 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 TIGRFAM TIGR00492 alr: alanine racemase 8 366 1.6E-111 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 47 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 Pfam PF01168 Alanine racemase, N-terminal domain 13 228 7.0E-66 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 Gene3D G3DSA:3.20.20.10 8 225 2.1E-45 T 29-03-2018 IPR029066 PLP-binding barrel SPSF3K_RS01735 2ccc5e0e925ee8484ee137e9a787a9e5 367 Pfam PF00842 Alanine racemase, C-terminal domain 242 366 4.9E-41 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS05850 dfaaa4aa5ea2b95495db406d282688b5 287 PIRSF PIRSF000812 1 282 7.6E-131 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase SPSF3K_RS05850 dfaaa4aa5ea2b95495db406d282688b5 287 Gene3D G3DSA:3.30.460.10 9 149 1.7E-41 T 29-03-2018 SPSF3K_RS05850 dfaaa4aa5ea2b95495db406d282688b5 287 SUPERFAMILY SSF81631 136 280 7.06E-57 T 29-03-2018 SPSF3K_RS05850 dfaaa4aa5ea2b95495db406d282688b5 287 SUPERFAMILY SSF81301 1 130 7.52E-48 T 29-03-2018 SPSF3K_RS05850 dfaaa4aa5ea2b95495db406d282688b5 287 Gene3D G3DSA:1.20.120.330 150 279 2.6E-53 T 29-03-2018 SPSF3K_RS05850 dfaaa4aa5ea2b95495db406d282688b5 287 Pfam PF04439 Streptomycin adenylyltransferase 1 276 4.8E-119 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase SPSF3K_RS04600 6cfa42fb6e34e53a2b07db27008cdd00 239 Gene3D G3DSA:3.40.1410.10 83 236 7.1E-15 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS04600 6cfa42fb6e34e53a2b07db27008cdd00 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 8.2E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS04600 6cfa42fb6e34e53a2b07db27008cdd00 239 Gene3D G3DSA:1.10.10.10 2 73 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04600 6cfa42fb6e34e53a2b07db27008cdd00 239 SUPERFAMILY SSF64288 59 234 7.85E-17 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS04600 6cfa42fb6e34e53a2b07db27008cdd00 239 Pfam PF07702 UTRA domain 90 228 3.0E-11 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS04600 6cfa42fb6e34e53a2b07db27008cdd00 239 SMART SM00345 12 71 5.4E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS04600 6cfa42fb6e34e53a2b07db27008cdd00 239 SUPERFAMILY SSF46785 6 79 7.67E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04600 6cfa42fb6e34e53a2b07db27008cdd00 239 SMART SM00866 88 231 5.6E-4 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 Gene3D G3DSA:2.70.210.12 3 153 1.5E-55 T 29-03-2018 IPR006169 GTP1/OBG domain SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 Gene3D G3DSA:3.40.50.300 154 195 0.01 T 29-03-2018 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 Pfam PF09269 Domain of unknown function (DUF1967) 368 436 1.3E-25 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 SUPERFAMILY SSF82051 3 159 3.79E-54 T 29-03-2018 IPR006169 GTP1/OBG domain SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 162 331 2.0E-13 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 336 1.8E-138 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 212 227 1.0E-33 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 229 247 1.0E-33 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 163 183 1.0E-33 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 184 202 1.0E-33 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 SUPERFAMILY SSF52540 152 339 3.62E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 Pfam PF01018 GTP1/OBG 6 158 1.2E-58 T 29-03-2018 IPR006169 GTP1/OBG domain SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 368 437 5.8E-26 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 SUPERFAMILY SSF102741 366 438 2.48E-24 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 Pfam PF01926 50S ribosome-binding GTPase 162 285 6.8E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 Hamap MF_01454 GTPase Obg [obg]. 3 338 46.454 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 PIRSF PIRSF002401 1 386 5.3E-137 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 Gene3D G3DSA:3.40.50.300 196 358 6.4E-25 T 29-03-2018 SPSF3K_RS08310 8067381de3bf560060be4d29861f6e9e 438 ProSitePatterns PS00905 GTP1/OBG family signature. 214 227 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 SPSF3K_RS05860 0449d1aee157d8937714beb9d63ca4e4 439 Gene3D G3DSA:3.90.350.10 118 354 7.2E-15 T 29-03-2018 IPR014736 Transposase, Tn5-like, core SPSF3K_RS05860 0449d1aee157d8937714beb9d63ca4e4 439 Pfam PF13701 Transposase DDE domain group 1 9 436 1.5E-151 T 29-03-2018 IPR025668 Transposase DDE domain SPSF3K_RS05860 0449d1aee157d8937714beb9d63ca4e4 439 SUPERFAMILY SSF53098 93 377 2.12E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS02595 b3e331240561d4a1249c6b9251d8d47b 198 Gene3D G3DSA:3.40.50.360 4 198 1.2E-30 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS02595 b3e331240561d4a1249c6b9251d8d47b 198 SUPERFAMILY SSF52218 18 191 2.35E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS02595 b3e331240561d4a1249c6b9251d8d47b 198 Pfam PF03358 NADPH-dependent FMN reductase 19 155 8.0E-23 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 237 356 5.1E-7 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 Gene3D G3DSA:1.20.272.10 243 357 1.1E-10 T 29-03-2018 SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 350 9.5E-137 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 SMART SM00382 36 176 7.4E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 SUPERFAMILY SSF48019 250 357 1.11E-12 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 Pfam PF13177 DNA polymerase III, delta subunit 20 177 4.4E-44 T 29-03-2018 SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 SUPERFAMILY SSF52540 33 222 5.75E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 Gene3D G3DSA:3.40.50.300 1 165 9.8E-42 T 29-03-2018 SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 123 141 1.7E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 40 58 1.7E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS08500 ec627be7a8c46e9b7bdb9ad172d1c4cb 558 Gene3D G3DSA:1.10.8.60 166 242 9.6E-20 T 29-03-2018 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 249 612 1.4E-95 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 214 2.2E-94 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 Pfam PF03129 Anticodon binding domain 522 611 2.8E-14 T 29-03-2018 IPR004154 Anticodon-binding SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 Gene3D G3DSA:3.90.960.10 279 416 6.2E-38 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 Gene3D G3DSA:3.30.930.10 1 278 1.3E-36 T 29-03-2018 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 Pfam PF04073 Aminoacyl-tRNA editing domain 295 410 2.8E-25 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 616 38.089 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 94 493 4.3E-56 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 Gene3D G3DSA:3.30.930.10 417 494 3.1E-9 T 29-03-2018 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 SUPERFAMILY SSF55826 256 423 5.23E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 SUPERFAMILY SSF52954 511 613 2.13E-23 T 29-03-2018 IPR004154 Anticodon-binding SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 Gene3D G3DSA:3.40.50.800 508 618 1.3E-20 T 29-03-2018 IPR004154 Anticodon-binding SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 6.2E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 6.2E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 6.2E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 6.2E-15 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 SUPERFAMILY SSF55681 9 241 1.83E-82 T 29-03-2018 SPSF3K_RS02570 95ae8deb2bbe05e1496f0d6f01835cc9 618 SUPERFAMILY SSF55681 441 524 1.83E-82 T 29-03-2018 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 137 151 6.6E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 6.6E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 SUPERFAMILY SSF53738 227 312 9.42E-20 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 SUPERFAMILY SSF53738 304 454 1.65E-30 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 Gene3D G3DSA:3.40.120.10 212 336 1.3E-32 T 29-03-2018 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 Gene3D G3DSA:3.40.120.10 17 211 4.4E-53 T 29-03-2018 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 138 147 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 325 451 4.8E-22 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 Gene3D G3DSA:3.40.120.10 337 455 3.9E-38 T 29-03-2018 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 223 311 7.3E-24 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 507 548 1.0E-8 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 Gene3D G3DSA:3.30.310.50 467 572 2.2E-22 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 SUPERFAMILY SSF55957 444 481 1.83E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 SUPERFAMILY SSF55957 512 571 1.83E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 SUPERFAMILY SSF53738 26 236 1.38E-45 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS06985 d6ab0c84de6ebe39760dc895ff152f77 572 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 179 8.7E-40 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS01785 6208a668f7ca63d1896d02664939724a 107 SUPERFAMILY SSF52821 9 101 6.02E-28 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01785 6208a668f7ca63d1896d02664939724a 107 Pfam PF00581 Rhodanese-like domain 17 102 1.8E-15 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01785 6208a668f7ca63d1896d02664939724a 107 SMART SM00450 15 107 1.3E-17 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01785 6208a668f7ca63d1896d02664939724a 107 Gene3D G3DSA:3.40.250.10 5 105 6.1E-27 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01010 d5211447e21f3d683de19fa418089de3 245 Pfam PF04397 LytTr DNA-binding domain 151 241 1.3E-20 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SPSF3K_RS01010 d5211447e21f3d683de19fa418089de3 245 Gene3D G3DSA:2.40.50.40 139 208 4.4E-13 T 29-03-2018 SPSF3K_RS01010 d5211447e21f3d683de19fa418089de3 245 SMART SM00850 148 242 8.7E-18 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SPSF3K_RS01010 d5211447e21f3d683de19fa418089de3 245 SUPERFAMILY SSF52172 1 127 1.01E-11 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS01010 d5211447e21f3d683de19fa418089de3 245 SMART SM00448 1 122 3.8E-10 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS01010 d5211447e21f3d683de19fa418089de3 245 Gene3D G3DSA:3.40.50.2300 1 138 2.3E-14 T 29-03-2018 SPSF3K_RS01010 d5211447e21f3d683de19fa418089de3 245 Pfam PF00072 Response regulator receiver domain 3 122 1.9E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 PRINTS PR00990 Ribokinase signature 106 119 2.2E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 PRINTS PR00990 Ribokinase signature 209 220 2.2E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 PRINTS PR00990 Ribokinase signature 6 27 2.2E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 PRINTS PR00990 Ribokinase signature 174 189 2.2E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 PRINTS PR00990 Ribokinase signature 33 52 2.2E-30 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 Gene3D G3DSA:3.40.1190.20 1 300 9.2E-64 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 SUPERFAMILY SSF53613 1 289 1.56E-72 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 291 4.4E-92 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 Hamap MF_01987 Ribokinase [rbsK]. 2 293 22.653 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SPSF3K_RS09025 d672f2e0b472f5cce9513a850b4a0a5f 303 Pfam PF00294 pfkB family carbohydrate kinase 1 286 2.9E-59 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 448 35.464 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 Gene3D G3DSA:3.40.1190.10 102 307 2.9E-56 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 446 8.7E-127 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 Gene3D G3DSA:3.90.190.20 314 447 7.4E-36 T 29-03-2018 SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 Pfam PF08245 Mur ligase middle domain 117 290 6.9E-37 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 SUPERFAMILY SSF53623 103 307 3.79E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 Gene3D G3DSA:3.40.50.720 1 101 1.9E-14 T 29-03-2018 SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 SUPERFAMILY SSF53244 309 447 8.61E-38 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 310 378 3.5E-10 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS08935 fa824da8c22a16d1bb2ec1ed6b4f1d51 452 SUPERFAMILY SSF51984 10 100 1.57E-16 T 29-03-2018 SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 135 624 3.4E-225 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 SUPERFAMILY SSF140990 438 632 1.19E-69 T 29-03-2018 SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 Gene3D G3DSA:3.40.50.300 163 370 5.4E-61 T 29-03-2018 SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 Pfam PF06480 FtsH Extracellular 14 128 6.4E-10 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 Gene3D G3DSA:1.10.8.60 371 444 3.4E-25 T 29-03-2018 SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 ProSitePatterns PS00674 AAA-protein family signature. 326 344 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 SUPERFAMILY SSF52540 182 426 1.08E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 Pfam PF01434 Peptidase family M41 418 623 4.9E-80 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 SMART SM00382 219 358 2.1E-23 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 223 355 2.0E-43 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SPSF3K_RS10850 f2ed70c71fd0073704ac4459d3d2b571 668 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 12 633 36.596 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 SUPERFAMILY SSF63520 272 372 5.89E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 SUPERFAMILY SSF52794 383 465 1.99E-7 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 Gene3D G3DSA:1.10.1790.10 273 373 5.3E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 Gene3D G3DSA:1.10.1790.10 167 260 0.02 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 Pfam PF00874 PRD domain 283 369 7.6E-13 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 Gene3D G3DSA:3.40.930.10 474 619 9.5E-19 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 Gene3D G3DSA:1.10.10.10 2 59 2.7E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 Gene3D G3DSA:1.10.10.10 85 152 1.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 Gene3D G3DSA:3.40.50.2300 381 473 1.5E-14 T 29-03-2018 SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 489 614 7.6E-15 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 SUPERFAMILY SSF55804 487 613 2.44E-18 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS00865 b01f65504c4fbbff5db51a950901c3eb 621 Pfam PF05043 Mga helix-turn-helix domain 90 161 2.8E-7 T 29-03-2018 IPR007737 Mga helix-turn-helix domain SPSF3K_RS02425 8377e0fc9d727dd37a55f0578089dccc 156 Pfam PF11217 Protein of unknown function (DUF3013) 1 155 1.4E-62 T 29-03-2018 IPR021380 Protein of unknown function DUF3013 SPSF3K_RS08585 f331f58c632b0cab5c6a940c1529b173 212 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 2 206 26.398 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08585 f331f58c632b0cab5c6a940c1529b173 212 Pfam PF02581 Thiamine monophosphate synthase 4 188 8.7E-58 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08585 f331f58c632b0cab5c6a940c1529b173 212 Gene3D G3DSA:3.20.20.70 1 206 1.5E-40 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS08585 f331f58c632b0cab5c6a940c1529b173 212 SUPERFAMILY SSF51391 2 204 9.29E-61 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08585 f331f58c632b0cab5c6a940c1529b173 212 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 3 200 4.4E-62 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS03585 7d4ca1ff0a13660733e2b10c7e80f513 209 Gene3D G3DSA:3.40.50.2020 3 207 2.4E-68 T 29-03-2018 SPSF3K_RS03585 7d4ca1ff0a13660733e2b10c7e80f513 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 2.0E-78 T 29-03-2018 SPSF3K_RS03585 7d4ca1ff0a13660733e2b10c7e80f513 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 49.172 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SPSF3K_RS03585 7d4ca1ff0a13660733e2b10c7e80f513 209 SUPERFAMILY SSF53271 5 207 7.21E-74 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS03585 7d4ca1ff0a13660733e2b10c7e80f513 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 9.6E-92 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 SUPERFAMILY SSF53720 17 278 1.03E-80 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 SUPERFAMILY SSF53720 336 468 1.03E-80 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 646 674 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 SUPERFAMILY SSF56796 463 875 6.28E-116 T 29-03-2018 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 Gene3D G3DSA:3.40.50.1970 445 657 1.4E-52 T 29-03-2018 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 PIRSF PIRSF000111 2 875 0.0 T 29-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 Pfam PF00171 Aldehyde dehydrogenase family 15 418 1.0E-25 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 Gene3D G3DSA:3.40.605.10 7 236 2.2E-26 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 Gene3D G3DSA:3.40.309.10 237 420 1.5E-28 T 29-03-2018 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 732 752 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 Gene3D G3DSA:1.20.1090.10 659 877 3.3E-59 T 29-03-2018 SPSF3K_RS10540 c29b66343577bc45f3ee37c485be129a 882 Pfam PF00465 Iron-containing alcohol dehydrogenase 472 862 7.9E-114 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 SPSF3K_RS08695 38fea3254943378377bcdda20f31291e 665 Pfam PF02705 K+ potassium transporter 18 551 7.0E-166 T 29-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 SPSF3K_RS08695 38fea3254943378377bcdda20f31291e 665 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 9 647 27.127 T 29-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup SPSF3K_RS10845 ceef342dcbf0064d67d5722e5d8137e8 463 Pfam PF13520 Amino acid permease 24 443 6.2E-49 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPSF3K_RS10845 ceef342dcbf0064d67d5722e5d8137e8 463 PIRSF PIRSF006060 5 463 3.4E-78 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 ProSitePatterns PS01155 Endonuclease III family signature. 104 133 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 Pfam PF00633 Helix-hairpin-helix motif 101 128 5.6E-7 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 Hamap MF_00942 Endonuclease III [nth]. 1 212 38.217 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 171 2.3E-23 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 Gene3D G3DSA:1.10.1670.10 119 215 4.6E-30 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 PIRSF PIRSF001435 4 215 9.7E-54 T 29-03-2018 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 190 206 - T 29-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 190 206 9.8E-6 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 TIGRFAM TIGR01083 nth: endonuclease III 6 197 2.8E-77 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 Gene3D G3DSA:1.10.340.30 23 118 3.0E-26 T 29-03-2018 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 SMART SM00525 189 209 4.0E-4 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 SUPERFAMILY SSF48150 6 212 6.28E-72 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SPSF3K_RS08130 52669dfd19a5227630f54295e4f58870 215 SMART SM00478 40 188 4.3E-57 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 29-03-2018 SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 SUPERFAMILY SSF56784 2 277 2.19E-59 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 246 3.8E-22 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 Gene3D G3DSA:3.40.50.1000 2 281 8.4E-37 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 273 8.1E-49 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 PIRSF PIRSF037492 1 462 3.2E-249 T 29-03-2018 IPR017223 Predicted hydrolase of the HAD superfamily, SPs0319-type SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 297 410 7.5E-29 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 Gene3D G3DSA:1.10.3420.10 287 457 6.8E-42 T 29-03-2018 SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 273 1.8E-60 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS01755 ecc48b65700211964d8544676d2b982f 462 ProSitePatterns PS01229 Hypothetical cof family signature 2. 227 249 - T 29-03-2018 SPSF3K_RS04890 18e8a6bdd167021ad59fe077dbdc4052 164 Gene3D G3DSA:1.20.5.620 51 127 3.7E-5 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SPSF3K_RS04890 18e8a6bdd167021ad59fe077dbdc4052 164 Pfam PF00430 ATP synthase B/B' CF(0) 12 141 3.7E-30 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SPSF3K_RS04890 18e8a6bdd167021ad59fe077dbdc4052 164 Hamap MF_01398 ATP synthase subunit b [atpF]. 6 143 12.614 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SPSF3K_RS04890 18e8a6bdd167021ad59fe077dbdc4052 164 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 17 160 2.4E-37 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 SPSF3K_RS04890 18e8a6bdd167021ad59fe077dbdc4052 164 SUPERFAMILY SSF81573 68 126 7.45E-7 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 130 150 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 2 300 1.4E-115 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 Gene3D G3DSA:3.50.50.60 124 233 2.2E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 Gene3D G3DSA:3.50.50.60 245 303 0.03 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.3E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 56 66 1.3E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 1.3E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 1.3E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 281 1.3E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.3E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 1.3E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 190 206 1.3E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 250 1.3E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 4.9E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 SUPERFAMILY SSF51905 1 299 9.43E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 5.1E-38 T 29-03-2018 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 5.1E-38 T 29-03-2018 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.1E-38 T 29-03-2018 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 5.1E-38 T 29-03-2018 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 5.1E-38 T 29-03-2018 SPSF3K_RS09750 6604c090f19daaf3626359994e42da4b 307 Gene3D G3DSA:3.50.50.60 1 123 1.7E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS03885 529e311f2bef02cfd7bac9c149643a78 351 Pfam PF02562 PhoH-like protein 112 315 5.0E-94 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 SPSF3K_RS03885 529e311f2bef02cfd7bac9c149643a78 351 SUPERFAMILY SSF52540 111 287 1.46E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03885 529e311f2bef02cfd7bac9c149643a78 351 Gene3D G3DSA:3.40.50.300 110 315 3.4E-28 T 29-03-2018 SPSF3K_RS03815 b4fab883e09718625cefb937101031b2 268 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 112 129 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 SPSF3K_RS03815 b4fab883e09718625cefb937101031b2 268 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 79 259 1.2E-50 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPSF3K_RS03815 b4fab883e09718625cefb937101031b2 268 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 91 106 5.1E-15 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPSF3K_RS03815 b4fab883e09718625cefb937101031b2 268 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 168 183 5.1E-15 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPSF3K_RS03815 b4fab883e09718625cefb937101031b2 268 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 117 129 5.1E-15 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPSF3K_RS03815 b4fab883e09718625cefb937101031b2 268 Gene3D G3DSA:2.40.100.10 55 267 3.3E-64 T 29-03-2018 IPR029000 Cyclophilin-like domain SPSF3K_RS03815 b4fab883e09718625cefb937101031b2 268 SUPERFAMILY SSF50891 78 263 6.57E-56 T 29-03-2018 IPR029000 Cyclophilin-like domain SPSF3K_RS10165 fa97ad0ac8542bef8f4d008d6345131b 88 Pfam PF13740 ACT domain 4 74 1.9E-11 T 29-03-2018 SPSF3K_RS10165 fa97ad0ac8542bef8f4d008d6345131b 88 Hamap MF_01054 UPF0237 protein . 1 88 23.607 T 29-03-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type SPSF3K_RS10165 fa97ad0ac8542bef8f4d008d6345131b 88 SUPERFAMILY SSF55021 1 82 1.32E-20 T 29-03-2018 SPSF3K_RS10165 fa97ad0ac8542bef8f4d008d6345131b 88 Gene3D G3DSA:3.30.70.260 1 83 1.8E-20 T 29-03-2018 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 SMART SM00870 3 315 3.0E-127 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 PIRSF PIRSF001220 1 319 1.5E-89 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 Gene3D G3DSA:3.40.50.1170 1 199 1.2E-50 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 77 87 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 SUPERFAMILY SSF53774 1 319 8.9E-92 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 PRINTS PR00139 Asparaginase/glutaminase family signature 76 94 9.4E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 9.4E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 PRINTS PR00139 Asparaginase/glutaminase family signature 250 268 9.4E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 Pfam PF00710 Asparaginase, N-terminal 3 187 4.7E-54 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 Gene3D G3DSA:3.40.50.40 200 320 8.0E-25 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 SPSF3K_RS01750 78987ce84ac837251e652cedbd26eae9 320 PIRSF PIRSF500176 1 320 3.9E-93 T 29-03-2018 SPSF3K_RS00995 641350b06386113e96cf52f0a27f480d 439 SUPERFAMILY SSF55874 302 417 3.01E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS00995 641350b06386113e96cf52f0a27f480d 439 Gene3D G3DSA:3.30.565.10 293 427 3.3E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS00995 641350b06386113e96cf52f0a27f480d 439 Pfam PF14501 GHKL domain 334 435 2.2E-11 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 1.6E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 242 257 1.6E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 1.6E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 1.6E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 314 330 1.6E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 548 1.4E-197 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 SUPERFAMILY SSF109604 334 491 1.47E-18 T 29-03-2018 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 Gene3D G3DSA:1.10.730.10 527 665 0.0068 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 676 25.906 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 Gene3D G3DSA:1.10.3210.10 317 492 7.0E-4 T 29-03-2018 SPSF3K_RS09875 398003f9c3ac82f3f6b5162a9c0ebb00 679 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 676 1.5E-214 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 SUPERFAMILY SSF51998 169 701 6.41E-169 T 29-03-2018 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 96 701 1.0E-149 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 11 719 0.0 T 29-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 Pfam PF02867 Ribonucleotide reductase, barrel domain 170 698 1.6E-137 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 Gene3D G3DSA:3.20.70.20 72 706 9.1E-153 T 29-03-2018 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 4.1E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 4.1E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 245 264 4.1E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 4.1E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 4.1E-22 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 Pfam PF08343 Ribonucleotide reductase N-terminal 11 91 2.6E-27 T 29-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 SUPERFAMILY SSF48168 22 168 1.83E-39 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08550 8f93f72886f7ec65d099a1283df68f58 719 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 95 165 6.5E-11 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS04055 0212d689383f8b4c372112b27a7104b0 361 SUPERFAMILY SSF53092 2 131 1.4E-23 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SPSF3K_RS04055 0212d689383f8b4c372112b27a7104b0 361 Gene3D G3DSA:3.40.350.10 1 131 5.2E-20 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SPSF3K_RS04055 0212d689383f8b4c372112b27a7104b0 361 Gene3D G3DSA:3.90.230.10 132 360 4.6E-73 T 29-03-2018 SPSF3K_RS04055 0212d689383f8b4c372112b27a7104b0 361 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 133 6.1E-18 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 SPSF3K_RS04055 0212d689383f8b4c372112b27a7104b0 361 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 289 301 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site SPSF3K_RS04055 0212d689383f8b4c372112b27a7104b0 361 Pfam PF00557 Metallopeptidase family M24 140 343 1.5E-58 T 29-03-2018 IPR000994 Peptidase M24 SPSF3K_RS04055 0212d689383f8b4c372112b27a7104b0 361 SUPERFAMILY SSF55920 132 358 2.88E-76 T 29-03-2018 IPR000994 Peptidase M24 SPSF3K_RS10550 c3e0572f8da421c83f50f1e817123a72 133 Gene3D G3DSA:2.20.110.10 54 133 3.1E-19 T 29-03-2018 SPSF3K_RS10550 c3e0572f8da421c83f50f1e817123a72 133 SUPERFAMILY SSF82185 49 130 3.66E-20 T 29-03-2018 SPSF3K_RS10550 c3e0572f8da421c83f50f1e817123a72 133 Pfam PF02493 MORN repeat 99 117 0.0042 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS10550 c3e0572f8da421c83f50f1e817123a72 133 Pfam PF02493 MORN repeat 53 74 4.9E-4 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS10550 c3e0572f8da421c83f50f1e817123a72 133 Pfam PF02493 MORN repeat 76 97 9.9E-5 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS10550 c3e0572f8da421c83f50f1e817123a72 133 PIRSF PIRSF034300 1 133 7.6E-52 T 29-03-2018 IPR014590 Uncharacterised conserved protein MORN repeat-containing SPSF3K_RS10550 c3e0572f8da421c83f50f1e817123a72 133 SMART SM00698 51 72 53.0 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS10550 c3e0572f8da421c83f50f1e817123a72 133 SMART SM00698 74 95 0.032 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS10550 c3e0572f8da421c83f50f1e817123a72 133 SMART SM00698 97 118 2.6 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS08035 d75a23f74dc899ff2e7569ab7506cb20 253 Gene3D G3DSA:3.40.50.300 1 250 5.8E-52 T 29-03-2018 SPSF3K_RS08035 d75a23f74dc899ff2e7569ab7506cb20 253 SUPERFAMILY SSF52540 11 234 9.27E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08035 d75a23f74dc899ff2e7569ab7506cb20 253 Pfam PF00005 ABC transporter 26 181 8.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08035 d75a23f74dc899ff2e7569ab7506cb20 253 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS08035 d75a23f74dc899ff2e7569ab7506cb20 253 SMART SM00382 35 230 3.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08980 3a5474f8374782ce093167ab8df9a3e5 582 Pfam PF00664 ABC transporter transmembrane region 19 291 3.4E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS08980 3a5474f8374782ce093167ab8df9a3e5 582 Gene3D G3DSA:1.20.1560.10 1 321 3.7E-66 T 29-03-2018 SPSF3K_RS08980 3a5474f8374782ce093167ab8df9a3e5 582 SMART SM00382 360 546 4.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08980 3a5474f8374782ce093167ab8df9a3e5 582 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS08980 3a5474f8374782ce093167ab8df9a3e5 582 Gene3D G3DSA:3.40.50.300 322 576 1.0E-66 T 29-03-2018 SPSF3K_RS08980 3a5474f8374782ce093167ab8df9a3e5 582 SUPERFAMILY SSF52540 331 570 1.44E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08980 3a5474f8374782ce093167ab8df9a3e5 582 SUPERFAMILY SSF90123 5 320 3.01E-77 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS08980 3a5474f8374782ce093167ab8df9a3e5 582 Pfam PF00005 ABC transporter 351 498 6.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08185 bb3f1c5618d84645e9870177200afb5f 267 Gene3D G3DSA:1.20.1510.10 86 266 3.6E-15 T 29-03-2018 SPSF3K_RS08185 bb3f1c5618d84645e9870177200afb5f 267 Pfam PF01545 Cation efflux family 95 263 3.5E-12 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPSF3K_RS08185 bb3f1c5618d84645e9870177200afb5f 267 SUPERFAMILY SSF161111 88 263 2.88E-25 T 29-03-2018 SPSF3K_RS08185 bb3f1c5618d84645e9870177200afb5f 267 Gene3D G3DSA:3.30.70.100 3 72 3.1E-11 T 29-03-2018 SPSF3K_RS08185 bb3f1c5618d84645e9870177200afb5f 267 SUPERFAMILY SSF55008 3 68 8.64E-13 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS08185 bb3f1c5618d84645e9870177200afb5f 267 Pfam PF00403 Heavy-metal-associated domain 8 62 5.0E-8 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 SUPERFAMILY SSF47384 194 273 2.75E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 Gene3D G3DSA:3.30.565.10 298 451 2.1E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 SMART SM00388 208 274 1.4E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 SMART SM00091 94 160 6.0E-9 T 29-03-2018 IPR000014 PAS domain SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 Gene3D G3DSA:1.10.287.130 205 270 7.4E-16 T 29-03-2018 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 390 2.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 376 2.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 415 2.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 434 2.6E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 209 273 8.3E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 436 7.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 Pfam PF00989 PAS fold 95 171 3.5E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 SUPERFAMILY SSF55785 84 200 4.36E-12 T 29-03-2018 IPR000014 PAS domain SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 Gene3D G3DSA:3.30.450.20 82 204 1.1E-18 T 29-03-2018 SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 SUPERFAMILY SSF55874 264 435 7.6E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 SMART SM00387 325 437 2.7E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04150 b7ef0e795de11c21df10b41f3b4a59ea 453 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 91 208 3.9E-8 T 29-03-2018 IPR000014 PAS domain SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 PIRSF PIRSF000654 525 575 2000.0 T 29-03-2018 SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 PIRSF PIRSF000654 34 265 1.1E-29 T 29-03-2018 SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 42 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 SMART SM00220 12 270 3.1E-61 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 Pfam PF00069 Protein kinase domain 12 233 9.0E-54 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 SUPERFAMILY SSF56112 8 276 1.48E-78 T 29-03-2018 IPR011009 Protein kinase-like domain SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 Gene3D G3DSA:1.10.510.10 81 576 2.5E-53 T 29-03-2018 SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 Pfam PF03793 PASTA domain 441 518 5.8E-5 T 29-03-2018 IPR005543 PASTA domain SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 Pfam PF03793 PASTA domain 365 428 4.2E-14 T 29-03-2018 IPR005543 PASTA domain SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 SMART SM00740 437 519 1.2 T 29-03-2018 IPR005543 PASTA domain SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 SMART SM00740 361 428 6.0E-18 T 29-03-2018 IPR005543 PASTA domain SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SPSF3K_RS09640 b2dd0c7fd49622232d36b682d3daab0e 579 Gene3D G3DSA:3.30.200.20 1 80 2.1E-22 T 29-03-2018 SPSF3K_RS06935 8b2bd968ca41dafe9602a1246077d1c0 415 SUPERFAMILY SSF46785 3 69 1.39E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06935 8b2bd968ca41dafe9602a1246077d1c0 415 SMART SM00345 8 67 3.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS06935 8b2bd968ca41dafe9602a1246077d1c0 415 Pfam PF00155 Aminotransferase class I and II 94 280 5.5E-16 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SPSF3K_RS06935 8b2bd968ca41dafe9602a1246077d1c0 415 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 1.8E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS06935 8b2bd968ca41dafe9602a1246077d1c0 415 SUPERFAMILY SSF53383 86 355 5.82E-48 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS06935 8b2bd968ca41dafe9602a1246077d1c0 415 Gene3D G3DSA:3.40.640.10 100 327 9.3E-24 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS06935 8b2bd968ca41dafe9602a1246077d1c0 415 Gene3D G3DSA:1.10.10.10 1 68 2.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04980 3a24658c7cef3b6eff354a0ec1544c10 1088 SUPERFAMILY SSF52980 749 930 2.41E-11 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SPSF3K_RS04980 3a24658c7cef3b6eff354a0ec1544c10 1088 SUPERFAMILY SSF52540 287 653 4.36E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04980 3a24658c7cef3b6eff354a0ec1544c10 1088 Hamap MF_01453 ATP-dependent helicase/deoxyribonuclease subunit B [rexB]. 2 1085 37.58 T 29-03-2018 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 SPSF3K_RS04980 3a24658c7cef3b6eff354a0ec1544c10 1088 Gene3D G3DSA:3.90.320.10 436 955 5.1E-15 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SPSF3K_RS04980 3a24658c7cef3b6eff354a0ec1544c10 1088 TIGRFAM TIGR02774 rexB_recomb: ATP-dependent nuclease subunit B 3 1079 0.0 T 29-03-2018 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 SPSF3K_RS04980 3a24658c7cef3b6eff354a0ec1544c10 1088 Gene3D G3DSA:3.40.50.300 1 133 6.5E-16 T 29-03-2018 SPSF3K_RS04980 3a24658c7cef3b6eff354a0ec1544c10 1088 Gene3D G3DSA:3.40.50.300 136 261 3.0E-15 T 29-03-2018 SPSF3K_RS04980 3a24658c7cef3b6eff354a0ec1544c10 1088 Pfam PF12705 PD-(D/E)XK nuclease superfamily 751 1034 1.4E-27 T 29-03-2018 SPSF3K_RS00155 8f70db4e87efa0a77f9e42c17ac843b1 90 PIRSF PIRSF037257 1 90 2.5E-28 T 29-03-2018 IPR009366 Protein Veg GO:0042710 SPSF3K_RS00155 8f70db4e87efa0a77f9e42c17ac843b1 90 Gene3D G3DSA:2.30.30.100 8 88 3.1E-27 T 29-03-2018 SPSF3K_RS00155 8f70db4e87efa0a77f9e42c17ac843b1 90 Pfam PF06257 Biofilm formation stimulator VEG 10 86 1.1E-24 T 29-03-2018 IPR009366 Protein Veg GO:0042710 SPSF3K_RS09670 5a66ec6ffbb902edddf6647a14b093d4 208 SUPERFAMILY SSF52540 4 190 1.15E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09670 5a66ec6ffbb902edddf6647a14b093d4 208 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 36.263 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SPSF3K_RS09670 5a66ec6ffbb902edddf6647a14b093d4 208 Gene3D G3DSA:3.30.63.10 37 83 1.6E-24 T 29-03-2018 SPSF3K_RS09670 5a66ec6ffbb902edddf6647a14b093d4 208 SMART SM00072 4 187 3.2E-73 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SPSF3K_RS09670 5a66ec6ffbb902edddf6647a14b093d4 208 Pfam PF00625 Guanylate kinase 7 185 7.6E-50 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SPSF3K_RS09670 5a66ec6ffbb902edddf6647a14b093d4 208 Gene3D G3DSA:3.40.50.300 1 28 0.011 T 29-03-2018 SPSF3K_RS09670 5a66ec6ffbb902edddf6647a14b093d4 208 Gene3D G3DSA:3.40.50.300 84 187 2.9E-29 T 29-03-2018 SPSF3K_RS09670 5a66ec6ffbb902edddf6647a14b093d4 208 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 2.3E-71 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 SPSF3K_RS09670 5a66ec6ffbb902edddf6647a14b093d4 208 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 SPSF3K_RS08335 c47bd0ad4edd94cadc3299b9de471ee5 123 Pfam PF03061 Thioesterase superfamily 26 101 2.9E-5 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SPSF3K_RS08335 c47bd0ad4edd94cadc3299b9de471ee5 123 Gene3D G3DSA:3.10.129.10 2 123 1.0E-12 T 29-03-2018 SPSF3K_RS08335 c47bd0ad4edd94cadc3299b9de471ee5 123 SUPERFAMILY SSF54637 3 121 1.37E-30 T 29-03-2018 IPR029069 HotDog domain SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 Pfam PF02357 Transcription termination factor nusG 7 114 2.5E-26 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 SUPERFAMILY SSF82679 7 118 1.57E-34 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 1.8E-6 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 PRINTS PR00338 Transcription termination factor NUSG signature 155 171 1.8E-6 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 SMART SM00738 6 117 7.8E-46 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 177 2.1E-45 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 179 20.813 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 SUPERFAMILY SSF50104 117 177 1.12E-11 T 29-03-2018 IPR008991 Translation protein SH3-like domain SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 Gene3D G3DSA:2.30.30.30 124 179 5.8E-14 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 Pfam PF00467 KOW motif 130 157 2.4E-7 T 29-03-2018 IPR005824 KOW SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 Gene3D G3DSA:3.30.70.940 6 121 5.3E-37 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 SPSF3K_RS00725 dac8ba0e21abd00378c469ed1cc4f7d3 179 SMART SM00739 127 154 2.9E-6 T 29-03-2018 IPR005824 KOW SPSF3K_RS02550 6f34061c7c34a4cf2fe62f93533e857a 128 SMART SM01323 1 83 1.6E-23 T 29-03-2018 IPR003849 Preprotein translocase YajC SPSF3K_RS02550 6f34061c7c34a4cf2fe62f93533e857a 128 Pfam PF02699 Preprotein translocase subunit 6 80 8.0E-18 T 29-03-2018 IPR003849 Preprotein translocase YajC SPSF3K_RS05440 d5fda4d1de63bb789f47c54a1f9c96b1 171 Gene3D G3DSA:3.40.430.10 1 167 3.7E-43 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SPSF3K_RS05440 d5fda4d1de63bb789f47c54a1f9c96b1 171 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 16 38 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 SPSF3K_RS05440 d5fda4d1de63bb789f47c54a1f9c96b1 171 Pfam PF00186 Dihydrofolate reductase 5 163 3.4E-52 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SPSF3K_RS05440 d5fda4d1de63bb789f47c54a1f9c96b1 171 PIRSF PIRSF000194 1 167 2.2E-48 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SPSF3K_RS05440 d5fda4d1de63bb789f47c54a1f9c96b1 171 SUPERFAMILY SSF53597 4 164 1.1E-50 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SPSF3K_RS05440 d5fda4d1de63bb789f47c54a1f9c96b1 171 PRINTS PR00070 Dihydrofolate reductase signature 43 54 1.0E-10 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SPSF3K_RS05440 d5fda4d1de63bb789f47c54a1f9c96b1 171 PRINTS PR00070 Dihydrofolate reductase signature 30 38 1.0E-10 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SPSF3K_RS05440 d5fda4d1de63bb789f47c54a1f9c96b1 171 PRINTS PR00070 Dihydrofolate reductase signature 96 110 1.0E-10 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SPSF3K_RS05440 d5fda4d1de63bb789f47c54a1f9c96b1 171 PRINTS PR00070 Dihydrofolate reductase signature 16 26 1.0E-10 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 SPSF3K_RS05360 b255742af81a4fc31546fe275b0da33d 403 SUPERFAMILY SSF81301 10 144 8.28E-42 T 29-03-2018 SPSF3K_RS05360 b255742af81a4fc31546fe275b0da33d 403 SUPERFAMILY SSF81891 146 398 1.44E-53 T 29-03-2018 SPSF3K_RS05360 b255742af81a4fc31546fe275b0da33d 403 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 253 396 3.1E-39 T 29-03-2018 IPR032810 CCA-adding enzyme, C-terminal SPSF3K_RS05360 b255742af81a4fc31546fe275b0da33d 403 Gene3D G3DSA:3.30.460.10 8 146 1.0E-45 T 29-03-2018 SPSF3K_RS05360 b255742af81a4fc31546fe275b0da33d 403 Gene3D G3DSA:1.10.3090.10 147 400 7.6E-39 T 29-03-2018 SPSF3K_RS05360 b255742af81a4fc31546fe275b0da33d 403 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 174 233 3.1E-16 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SPSF3K_RS05360 b255742af81a4fc31546fe275b0da33d 403 Pfam PF01743 Poly A polymerase head domain 27 147 1.7E-35 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 SPSF3K_RS05360 b255742af81a4fc31546fe275b0da33d 403 Hamap MF_01263 CCA-adding enzyme [cca]. 7 400 41.898 T 29-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 Gene3D G3DSA:3.40.50.10380 1 256 8.8E-89 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 Pfam PF03949 Malic enzyme, NAD binding domain 259 514 2.5E-97 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 Gene3D G3DSA:3.40.50.720 257 540 1.2E-94 T 29-03-2018 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 SMART SM00919 259 515 4.5E-103 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 SUPERFAMILY SSF53223 3 258 4.53E-92 T 29-03-2018 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 PRINTS PR00072 Malic enzyme signature 255 271 3.2E-60 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 PRINTS PR00072 Malic enzyme signature 135 164 3.2E-60 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 PRINTS PR00072 Malic enzyme signature 171 193 3.2E-60 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 PRINTS PR00072 Malic enzyme signature 393 409 3.2E-60 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 PRINTS PR00072 Malic enzyme signature 73 97 3.2E-60 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 PRINTS PR00072 Malic enzyme signature 230 248 3.2E-60 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 PRINTS PR00072 Malic enzyme signature 286 302 3.2E-60 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 Pfam PF00390 Malic enzyme, N-terminal domain 68 249 4.4E-64 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 ProSitePatterns PS00331 Malic enzymes signature. 255 271 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 SMART SM01274 67 249 1.2E-80 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 PIRSF PIRSF000106 1 540 7.3E-200 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SPSF3K_RS02380 81733b0f16478246e0a13314753d07d2 540 SUPERFAMILY SSF51735 259 540 7.48E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 Gene3D G3DSA:3.60.20.10 2 239 1.4E-61 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 604 37.677 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 Gene3D G3DSA:3.40.50.10490 240 455 2.1E-49 T 29-03-2018 SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 Pfam PF01380 SIS domain 290 413 3.4E-25 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 Pfam PF01380 SIS domain 460 585 3.6E-15 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 SUPERFAMILY SSF56235 2 233 4.55E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 Gene3D G3DSA:3.40.50.10490 456 602 5.4E-40 T 29-03-2018 SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 SUPERFAMILY SSF53697 246 604 1.61E-87 T 29-03-2018 SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 604 1.7E-207 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 SPSF3K_RS07250 46855e10089de8be01b32827bd11eff1 604 Pfam PF13522 Glutamine amidotransferase domain 63 189 5.6E-21 T 29-03-2018 SPSF3K_RS03400 ee1f6c9f4d5afca7d91521af0ae131d8 93 Pfam PF08951 Enterocin A Immunity 10 74 2.2E-11 T 29-03-2018 IPR015046 Enterocin A Immunity SPSF3K_RS03400 ee1f6c9f4d5afca7d91521af0ae131d8 93 Gene3D G3DSA:1.20.1440.50 6 85 1.7E-10 T 29-03-2018 IPR023130 Ta0600-like domain SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 1.2E-135 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 PIRSF PIRSF002158 5 276 9.8E-98 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 SMART SM01382 124 253 5.8E-88 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 2.2E-55 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 SMART SM01383 42 118 2.0E-45 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 Gene3D G3DSA:2.40.50.140 1 114 5.7E-49 T 29-03-2018 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 SUPERFAMILY SSF50104 126 273 6.62E-58 T 29-03-2018 IPR008991 Translation protein SH3-like domain SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 SUPERFAMILY SSF50249 3 125 2.26E-51 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.037 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 Gene3D G3DSA:4.10.950.10 197 275 3.3E-33 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.5E-34 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10505 f6f7793b7620e4578940de208cfa9f15 277 Gene3D G3DSA:2.30.30.30 119 195 7.6E-33 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 SPSF3K_RS02435 ff7e163210326ee839b5062e4165dc1f 247 Pfam PF04452 RNA methyltransferase 14 241 3.0E-67 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS02435 ff7e163210326ee839b5062e4165dc1f 247 SUPERFAMILY SSF75217 69 244 2.47E-50 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SPSF3K_RS02435 ff7e163210326ee839b5062e4165dc1f 247 SUPERFAMILY SSF88697 3 53 1.94E-9 T 29-03-2018 IPR015947 PUA-like domain SPSF3K_RS02435 ff7e163210326ee839b5062e4165dc1f 247 Gene3D G3DSA:3.40.1280.10 1 247 8.2E-65 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPSF3K_RS02435 ff7e163210326ee839b5062e4165dc1f 247 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 16 244 1.7E-49 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS02435 ff7e163210326ee839b5062e4165dc1f 247 PIRSF PIRSF015601 1 245 5.2E-47 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 3.8E-23 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 1.2E-25 T 29-03-2018 IPR000362 Fumarate lyase family SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 1.2E-25 T 29-03-2018 IPR000362 Fumarate lyase family SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 1.2E-25 T 29-03-2018 IPR000362 Fumarate lyase family SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.2E-25 T 29-03-2018 IPR000362 Fumarate lyase family SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 Pfam PF00206 Lyase 7 286 2.5E-70 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 Gene3D G3DSA:1.10.275.10 2 92 1.7E-26 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 SUPERFAMILY SSF48557 3 427 1.08E-135 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 3.0E-169 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 Gene3D G3DSA:1.10.40.30 349 428 9.7E-26 T 29-03-2018 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 Gene3D G3DSA:1.20.200.10 93 348 1.1E-74 T 29-03-2018 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 2.8E-9 T 29-03-2018 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 2.8E-9 T 29-03-2018 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 2.8E-9 T 29-03-2018 SPSF3K_RS10570 e3db616f043944fc6e2b02cbc388e44e 430 SMART SM00998 349 429 2.2E-37 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 367 375 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 Gene3D G3DSA:3.20.20.80 3 472 1.1E-154 T 29-03-2018 SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 Pfam PF00232 Glycosyl hydrolase family 1 7 468 3.7E-144 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 409 426 1.3E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 433 445 1.3E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 367 375 1.3E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 1.3E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 388 399 1.3E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPSF3K_RS06330 5c6f3ea048ad8bc8f8ccbaca0c460d0a 473 SUPERFAMILY SSF51445 7 469 1.76E-158 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS07480 8f183476b19c72d3776f18840c3b2f4b 187 SUPERFAMILY SSF50249 6 183 4.11E-47 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS07480 8f183476b19c72d3776f18840c3b2f4b 187 Pfam PF10991 Protein of unknown function (DUF2815) 9 178 2.5E-59 T 29-03-2018 IPR022595 Protein of unknown function DUF2815 SPSF3K_RS07480 8f183476b19c72d3776f18840c3b2f4b 187 Gene3D G3DSA:2.40.50.140 5 186 1.1E-59 T 29-03-2018 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 Gene3D G3DSA:3.30.300.10 144 245 1.6E-48 T 29-03-2018 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 PIRSF PIRSF000497 1 396 1.6E-172 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 Gene3D G3DSA:3.30.300.10 12 143 4.2E-41 T 29-03-2018 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 395 56.274 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 Pfam PF02772 S-adenosylmethionine synthetase, central domain 126 243 2.7E-48 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 SUPERFAMILY SSF55973 124 244 2.83E-51 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 127 137 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 Gene3D G3DSA:3.30.300.10 258 396 1.0E-45 T 29-03-2018 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 271 279 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 394 2.0E-176 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 SUPERFAMILY SSF55973 5 110 2.06E-42 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 101 1.2E-38 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 SUPERFAMILY SSF55973 245 394 7.06E-67 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS08485 ff478c8778f4ea8a289783d433a0d298 397 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 245 384 1.7E-67 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 SMART SM00434 9 462 3.5E-282 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 SUPERFAMILY SSF101904 497 816 2.49E-107 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Gene3D G3DSA:3.30.1360.40 234 330 4.4E-34 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 806 24.317 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 469 1.1E-157 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Gene3D G3DSA:2.120.10.90 497 823 2.6E-119 T 29-03-2018 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 707 742 2.5E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 759 804 1.7E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 502 547 3.2E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 610 653 5.0E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 658 703 7.1E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 552 599 4.9E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 7 804 0.0 T 29-03-2018 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Gene3D G3DSA:3.90.199.10 32 212 1.5E-83 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 Gene3D G3DSA:1.10.268.10 342 484 2.0E-52 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS06415 fe28bce8db8b6ed5d5588ff5d1fe1c90 838 SUPERFAMILY SSF56719 29 484 1.29E-175 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SPSF3K_RS08680 e4217bd37ce06f0d39c7152e776957ba 246 Pfam PF01553 Acyltransferase 22 143 1.3E-16 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SPSF3K_RS08680 e4217bd37ce06f0d39c7152e776957ba 246 Gene3D G3DSA:3.40.1130.10 1 202 3.3E-34 T 29-03-2018 SPSF3K_RS08680 e4217bd37ce06f0d39c7152e776957ba 246 SMART SM00563 36 146 1.4E-21 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SPSF3K_RS08680 e4217bd37ce06f0d39c7152e776957ba 246 SUPERFAMILY SSF69593 2 199 3.14E-55 T 29-03-2018 SPSF3K_RS01025 ac214afec3c1a091eb6103c880880f94 121 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 18.349 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SPSF3K_RS01025 ac214afec3c1a091eb6103c880880f94 121 SUPERFAMILY SSF54211 1 113 4.05E-31 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS01025 ac214afec3c1a091eb6103c880880f94 121 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 8 98 2.0E-32 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SPSF3K_RS01025 ac214afec3c1a091eb6103c880880f94 121 Gene3D G3DSA:3.30.230.10 1 116 5.3E-32 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS01025 ac214afec3c1a091eb6103c880880f94 121 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 106 4.0E-27 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SPSF3K_RS01025 ac214afec3c1a091eb6103c880880f94 121 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 52 66 - T 29-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 SPSF3K_RS01025 ac214afec3c1a091eb6103c880880f94 121 Pfam PF00825 Ribonuclease P 1 106 1.6E-30 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 Gene3D G3DSA:1.10.10.60 2 56 0.0016 T 29-03-2018 SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 Pfam PF12833 Helix-turn-helix domain 29 103 8.6E-15 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 SUPERFAMILY SSF55136 125 277 4.19E-33 T 29-03-2018 SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 56 98 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 SMART SM00342 19 102 4.2E-12 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 Gene3D G3DSA:1.10.10.60 57 108 1.9E-9 T 29-03-2018 SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 Gene3D G3DSA:3.20.80.10 109 276 7.9E-37 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 Pfam PF06445 GyrI-like small molecule binding domain 125 275 2.8E-25 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 SMART SM00871 125 276 2.1E-28 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding SPSF3K_RS05645 82f02e89ed79967e5518ccea3d2ea455 278 SUPERFAMILY SSF46689 56 105 6.72E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS01765 d4527ba5a2d24ef453b182553ccb71ea 404 SUPERFAMILY SSF53383 7 402 1.34E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS01765 d4527ba5a2d24ef453b182553ccb71ea 404 Gene3D G3DSA:3.40.640.10 53 280 4.2E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS01765 d4527ba5a2d24ef453b182553ccb71ea 404 Pfam PF00155 Aminotransferase class I and II 34 383 6.9E-47 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SPSF3K_RS01765 d4527ba5a2d24ef453b182553ccb71ea 404 Gene3D G3DSA:3.90.1150.10 281 404 1.5E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS00225 4cfa3e8878a79247cd32b2a0fdf81765 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 284 2.9E-35 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SPSF3K_RS00225 4cfa3e8878a79247cd32b2a0fdf81765 287 Gene3D G3DSA:3.40.50.720 1 185 1.1E-57 T 29-03-2018 SPSF3K_RS00225 4cfa3e8878a79247cd32b2a0fdf81765 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 185 3.1E-67 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SPSF3K_RS00225 4cfa3e8878a79247cd32b2a0fdf81765 287 SUPERFAMILY SSF48179 187 286 3.91E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPSF3K_RS00225 4cfa3e8878a79247cd32b2a0fdf81765 287 PIRSF PIRSF000105 1 287 1.6E-95 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 SPSF3K_RS00225 4cfa3e8878a79247cd32b2a0fdf81765 287 Gene3D G3DSA:1.10.1040.10 186 287 2.5E-34 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPSF3K_RS00225 4cfa3e8878a79247cd32b2a0fdf81765 287 SUPERFAMILY SSF51735 1 184 1.32E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 603 2.4E-287 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 Gene3D G3DSA:2.40.50.250 501 578 1.9E-35 T 29-03-2018 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 146 1.9E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 Pfam PF00679 Elongation factor G C-terminus 402 481 1.3E-24 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 Gene3D G3DSA:2.40.30.10 200 307 3.3E-21 T 29-03-2018 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 SUPERFAMILY SSF50447 155 304 2.29E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 Gene3D G3DSA:3.30.70.870 308 404 4.0E-30 T 29-03-2018 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 Pfam PF03144 Elongation factor Tu domain 2 224 294 6.4E-13 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 SMART SM00838 400 485 2.4E-5 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 Gene3D G3DSA:3.40.50.300 2 70 2.5E-9 T 29-03-2018 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 Gene3D G3DSA:3.30.70.240 405 500 5.3E-22 T 29-03-2018 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 SUPERFAMILY SSF52540 4 211 3.43E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 SUPERFAMILY SSF54980 307 392 1.08E-14 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 SUPERFAMILY SSF54980 403 518 2.83E-29 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 Gene3D G3DSA:3.40.50.300 71 199 1.2E-29 T 29-03-2018 SPSF3K_RS08945 65cd445f4a3e76a3509aa48aaadd91db 613 Pfam PF00009 Elongation factor Tu GTP binding domain 7 200 1.3E-54 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 Gene3D G3DSA:3.40.50.300 233 434 5.1E-36 T 29-03-2018 SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 SUPERFAMILY SSF52540 371 580 3.67E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 Pfam PF17191 RecG wedge domain 9 157 4.0E-12 T 29-03-2018 IPR033454 RecG, wedge domain SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 Pfam PF00271 Helicase conserved C-terminal domain 455 566 3.7E-19 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 641 9.4E-240 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 Gene3D G3DSA:2.40.50.140 44 135 5.5E-6 T 29-03-2018 SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 SUPERFAMILY SSF52540 169 430 7.68E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 SUPERFAMILY SSF50249 1 161 4.11E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 SMART SM00487 249 437 2.2E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 Pfam PF00270 DEAD/DEAH box helicase 256 411 5.7E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 Gene3D G3DSA:3.40.50.300 435 607 1.3E-30 T 29-03-2018 SPSF3K_RS01740 d55c906dd49dba655faeaf35d3fbde52 671 SMART SM00490 486 567 6.1E-21 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 SUPERFAMILY SSF52833 4 101 1.79E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 SUPERFAMILY SSF52833 104 194 7.84E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 SUPERFAMILY SSF51905 207 507 5.94E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 Gene3D G3DSA:3.50.50.60 197 326 2.1E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 Pfam PF13192 Thioredoxin domain 124 194 3.1E-9 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 Gene3D G3DSA:3.50.50.60 327 437 1.0E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 Gene3D G3DSA:3.40.30.10 102 196 1.7E-6 T 29-03-2018 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 309 317 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 346 370 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 331 343 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 398 414 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 436 457 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 471 489 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PIRSF PIRSF000238 2 511 2.6E-243 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 338 358 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 492 3.6E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 308 326 2.2E-36 T 29-03-2018 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 350 368 2.2E-36 T 29-03-2018 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 434 450 2.2E-36 T 29-03-2018 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 461 483 2.2E-36 T 29-03-2018 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 2.2E-36 T 29-03-2018 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 Gene3D G3DSA:3.50.50.60 438 511 3.9E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 Gene3D G3DSA:3.40.30.10 3 93 3.5E-22 T 29-03-2018 SPSF3K_RS00600 fa7fb2558f431110ffa970bf6103d8e0 511 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 5 511 5.3E-228 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 SPSF3K_RS08930 e071e921519022a097ae2c70a0f70f3a 357 SUPERFAMILY SSF53756 3 342 7.22E-75 T 29-03-2018 SPSF3K_RS08930 e071e921519022a097ae2c70a0f70f3a 357 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 144 2.0E-36 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SPSF3K_RS08930 e071e921519022a097ae2c70a0f70f3a 357 Gene3D G3DSA:3.40.50.2000 156 344 5.0E-23 T 29-03-2018 SPSF3K_RS08930 e071e921519022a097ae2c70a0f70f3a 357 Gene3D G3DSA:3.40.50.2000 1 155 1.6E-22 T 29-03-2018 SPSF3K_RS08930 e071e921519022a097ae2c70a0f70f3a 357 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 335 3.6E-25 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SPSF3K_RS02315 8e4caf978e938a73d2929344bff2baed 145 SUPERFAMILY SSF46955 2 112 1.1E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS02315 8e4caf978e938a73d2929344bff2baed 145 Gene3D G3DSA:1.10.1660.10 1 55 7.7E-17 T 29-03-2018 SPSF3K_RS02315 8e4caf978e938a73d2929344bff2baed 145 SMART SM00422 2 70 3.0E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02315 8e4caf978e938a73d2929344bff2baed 145 Pfam PF13411 MerR HTH family regulatory protein 2 65 4.0E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02315 8e4caf978e938a73d2929344bff2baed 145 Gene3D G3DSA:1.10.1660.10 56 138 7.2E-11 T 29-03-2018 SPSF3K_RS07910 10a0f3942a6038d24bc021b5fd2b9f21 215 Pfam PF01966 HD domain 29 126 1.4E-6 T 29-03-2018 IPR006674 HD domain SPSF3K_RS07910 10a0f3942a6038d24bc021b5fd2b9f21 215 SMART SM00471 22 136 1.5E-6 T 29-03-2018 IPR003607 HD/PDEase domain SPSF3K_RS07910 10a0f3942a6038d24bc021b5fd2b9f21 215 SUPERFAMILY SSF109604 1 213 1.28E-69 T 29-03-2018 SPSF3K_RS07910 10a0f3942a6038d24bc021b5fd2b9f21 215 Gene3D G3DSA:1.10.3210.10 6 215 3.3E-20 T 29-03-2018 SPSF3K_RS05890 2babdeb388b297cf9839bb6164cde105 94 SUPERFAMILY SSF57783 12 46 2.55E-7 T 29-03-2018 SPSF3K_RS05890 2babdeb388b297cf9839bb6164cde105 94 Gene3D G3DSA:3.30.65.10 2 54 3.3E-11 T 29-03-2018 SPSF3K_RS05890 2babdeb388b297cf9839bb6164cde105 94 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 10 39 4.7E-11 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 58 292 2.0E-53 T 29-03-2018 SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 188 216 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 Gene3D G3DSA:3.40.50.720 4 296 1.3E-65 T 29-03-2018 SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 SUPERFAMILY SSF51735 50 293 7.09E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 140 9.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 181 189 9.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 201 220 9.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 239 3.9E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 257 277 3.9E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 3.9E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 53 70 3.9E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS05635 a26c92def64b7c56e9fdb74fdae72fbf 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 220 3.9E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS09220 9aac0cb56800168faf084dcac1356237 396 Pfam PF07690 Major Facilitator Superfamily 17 357 8.1E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS09220 9aac0cb56800168faf084dcac1356237 396 Gene3D G3DSA:1.20.1250.20 209 395 8.4E-16 T 29-03-2018 SPSF3K_RS09220 9aac0cb56800168faf084dcac1356237 396 Gene3D G3DSA:1.20.1250.20 2 196 3.7E-20 T 29-03-2018 SPSF3K_RS09220 9aac0cb56800168faf084dcac1356237 396 SUPERFAMILY SSF103473 5 392 1.1E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 SUPERFAMILY SSF50249 105 186 2.83E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 SUPERFAMILY SSF50249 192 279 1.12E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 SMART SM00316 192 262 1.7E-25 T 29-03-2018 IPR022967 RNA-binding domain, S1 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 SMART SM00316 277 348 4.5E-27 T 29-03-2018 IPR022967 RNA-binding domain, S1 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 SMART SM00316 105 173 3.5E-9 T 29-03-2018 IPR022967 RNA-binding domain, S1 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 SMART SM00316 15 91 1.1E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 Gene3D G3DSA:2.40.50.140 2 96 2.5E-9 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 Gene3D G3DSA:2.40.50.140 279 387 1.7E-29 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 PRINTS PR00681 Ribosomal protein S1 signature 331 349 3.1E-37 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 PRINTS PR00681 Ribosomal protein S1 signature 17 35 3.1E-37 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 PRINTS PR00681 Ribosomal protein S1 signature 110 126 3.1E-37 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 PRINTS PR00681 Ribosomal protein S1 signature 128 145 3.1E-37 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 PRINTS PR00681 Ribosomal protein S1 signature 157 177 3.1E-37 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 PRINTS PR00681 Ribosomal protein S1 signature 292 311 3.1E-37 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 PRINTS PR00681 Ribosomal protein S1 signature 214 235 3.1E-37 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 SUPERFAMILY SSF50249 262 351 1.42E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 SUPERFAMILY SSF50249 4 103 7.01E-13 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 Pfam PF00575 S1 RNA binding domain 191 262 4.3E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 Pfam PF00575 S1 RNA binding domain 106 173 2.2E-12 T 29-03-2018 IPR003029 S1 domain GO:0003676 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 Pfam PF00575 S1 RNA binding domain 14 74 4.9E-9 T 29-03-2018 IPR003029 S1 domain GO:0003676 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 Pfam PF00575 S1 RNA binding domain 276 348 4.9E-25 T 29-03-2018 IPR003029 S1 domain GO:0003676 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 Gene3D G3DSA:2.40.50.140 184 267 2.3E-25 T 29-03-2018 SPSF3K_RS07570 8199b3f00252f9a3c93cbe53dd921581 410 Gene3D G3DSA:2.40.50.140 104 179 7.4E-11 T 29-03-2018 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 397 39.64 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 Gene3D G3DSA:3.40.50.1260 186 385 1.3E-75 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PRINTS PR00477 Phosphoglycerate kinase family signature 174 196 1.1E-91 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PRINTS PR00477 Phosphoglycerate kinase family signature 350 361 1.1E-91 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 1.1E-91 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PRINTS PR00477 Phosphoglycerate kinase family signature 143 165 1.1E-91 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 1.1E-91 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.1E-91 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PRINTS PR00477 Phosphoglycerate kinase family signature 316 341 1.1E-91 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.1E-91 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PRINTS PR00477 Phosphoglycerate kinase family signature 197 216 1.1E-91 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 PIRSF PIRSF000724 1 398 7.3E-132 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 Pfam PF00162 Phosphoglycerate kinase 6 387 6.8E-146 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 Gene3D G3DSA:3.40.50.1260 3 185 1.2E-66 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 SUPERFAMILY SSF53748 3 397 1.3E-143 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01210 79f16ee8bc795a55b130b0511bfafc11 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS04930 eab12586886069e34047fc74840beb93 62 Pfam PF11772 DNA-directed RNA polymerase subunit beta 15 61 6.3E-20 T 29-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA SPSF3K_RS04930 eab12586886069e34047fc74840beb93 62 ProDom PD053619 EPUA PRECURSOR SIGNAL PEPTIDE YFDG EXTRACELLULAR OB2955 BH3736 GBS0884 SMU.1524C 1 59 8.0E-9 T 29-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 Gene3D G3DSA:3.30.70.270 54 125 3.8E-23 T 29-03-2018 SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 Gene3D G3DSA:3.30.70.270 126 183 3.2E-16 T 29-03-2018 SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 Hamap MF_01113 DNA polymerase IV [dinB]. 11 364 36.999 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 Gene3D G3DSA:3.30.1490.100 258 361 5.3E-22 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 SUPERFAMILY SSF100879 251 352 1.0E-21 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 Pfam PF11798 IMS family HHH motif 179 210 6.1E-8 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 Pfam PF11799 impB/mucB/samB family C-terminal domain 246 358 1.7E-17 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 Pfam PF00817 impB/mucB/samB family 17 167 1.2E-48 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 SUPERFAMILY SSF56672 5 247 5.25E-90 T 29-03-2018 SPSF3K_RS01570 da16dacba7e9911d6be4183c0da7f974 364 Gene3D G3DSA:1.10.150.20 184 257 3.6E-18 T 29-03-2018 SPSF3K_RS07135 53204d6a8d56be38d0511766223c2cd9 181 Gene3D G3DSA:1.10.10.60 7 46 1.0E-9 T 29-03-2018 SPSF3K_RS07135 53204d6a8d56be38d0511766223c2cd9 181 Gene3D G3DSA:1.10.10.60 47 149 9.1E-6 T 29-03-2018 SPSF3K_RS07135 53204d6a8d56be38d0511766223c2cd9 181 SUPERFAMILY SSF46689 4 68 5.13E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS07135 53204d6a8d56be38d0511766223c2cd9 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 59 2.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 SUPERFAMILY SSF52768 23 328 3.06E-70 T 29-03-2018 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 Gene3D G3DSA:3.40.800.10 22 335 2.4E-67 T 29-03-2018 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 PIRSF PIRSF036979 30 329 8.0E-37 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 Hamap MF_00737 Formimidoylglutamase [hutG]. 8 323 36.884 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 PRINTS PR00116 Arginase signature 130 145 6.3E-6 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 PRINTS PR00116 Arginase signature 156 183 6.3E-6 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 PRINTS PR00116 Arginase signature 284 298 6.3E-6 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 PRINTS PR00116 Arginase signature 249 278 6.3E-6 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 TIGRFAM TIGR01227 hutG: formimidoylglutamase 48 319 9.6E-69 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 ProSitePatterns PS01053 Arginase family signature. 252 273 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 SPSF3K_RS04365 04d3b7199770fa41f8e07a6b62323f0c 336 Pfam PF00491 Arginase family 49 320 3.3E-52 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 SPSF3K_RS04725 f07cfe3df26bc8dd1872948276c34c9f 147 PIRSF PIRSF034303 1 145 1.3E-37 T 29-03-2018 IPR012543 Protein of unknown function DUF1694 SPSF3K_RS04725 f07cfe3df26bc8dd1872948276c34c9f 147 Gene3D G3DSA:3.30.1330.30 2 125 8.7E-35 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SPSF3K_RS04725 f07cfe3df26bc8dd1872948276c34c9f 147 SUPERFAMILY SSF160515 1 128 3.92E-33 T 29-03-2018 SPSF3K_RS04725 f07cfe3df26bc8dd1872948276c34c9f 147 Pfam PF07997 Protein of unknown function (DUF1694) 2 119 2.0E-30 T 29-03-2018 IPR012543 Protein of unknown function DUF1694 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 PRINTS PR00625 DnaJ domain signature 41 61 5.8E-30 T 29-03-2018 IPR001623 DnaJ domain SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 PRINTS PR00625 DnaJ domain signature 61 80 5.8E-30 T 29-03-2018 IPR001623 DnaJ domain SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 PRINTS PR00625 DnaJ domain signature 25 40 5.8E-30 T 29-03-2018 IPR001623 DnaJ domain SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 PRINTS PR00625 DnaJ domain signature 7 25 5.8E-30 T 29-03-2018 IPR001623 DnaJ domain SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 Gene3D G3DSA:2.10.230.10 145 201 1.9E-16 T 29-03-2018 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 355 1.7E-138 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 375 39.572 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 SUPERFAMILY SSF46565 1 106 8.64E-34 T 29-03-2018 IPR001623 DnaJ domain SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 29-03-2018 IPR018253 DnaJ domain, conserved site SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 SMART SM00271 4 61 3.1E-27 T 29-03-2018 IPR001623 DnaJ domain SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 SUPERFAMILY SSF49493 115 139 3.53E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 SUPERFAMILY SSF49493 218 268 3.53E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 Pfam PF00226 DnaJ domain 6 66 3.6E-24 T 29-03-2018 IPR001623 DnaJ domain SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 Pfam PF00684 DnaJ central domain 148 212 5.8E-14 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 SUPERFAMILY SSF49493 264 349 4.32E-23 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 Gene3D G3DSA:1.10.287.110 1 116 2.5E-34 T 29-03-2018 IPR001623 DnaJ domain SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 Gene3D G3DSA:2.60.260.20 260 370 4.3E-29 T 29-03-2018 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 SUPERFAMILY SSF57938 135 215 1.31E-19 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 Pfam PF01556 DnaJ C terminal domain 121 338 6.3E-42 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal SPSF3K_RS10125 fa7240741259d7f46246a6a3d8701542 379 Gene3D G3DSA:2.60.260.20 202 259 5.7E-19 T 29-03-2018 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 SUPERFAMILY SSF52440 549 668 7.77E-46 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 SUPERFAMILY SSF48108 395 547 1.57E-49 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Gene3D G3DSA:3.30.470.20 120 401 5.5E-65 T 29-03-2018 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 SUPERFAMILY SSF52440 2 127 7.05E-50 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 SUPERFAMILY SSF56059 128 399 8.84E-107 T 29-03-2018 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Pfam PF02142 MGS-like domain 950 1036 3.8E-17 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 9.9E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 9.9E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 9.9E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 9.9E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 9.9E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 9.9E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 9.9E-63 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 SUPERFAMILY SSF56059 666 927 6.54E-102 T 29-03-2018 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 1.4E-39 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Gene3D G3DSA:3.40.50.20 532 647 9.0E-58 T 29-03-2018 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Gene3D G3DSA:1.10.1030.10 402 531 3.7E-46 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Gene3D G3DSA:3.30.1490.20 648 737 2.4E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 SUPERFAMILY SSF52335 936 1053 1.83E-27 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 SMART SM01209 665 837 0.0019 T 29-03-2018 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 SMART SM00851 949 1036 3.1E-22 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 SMART SM01096 420 540 3.4E-63 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 12.993 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Gene3D G3DSA:3.30.470.20 738 927 5.4E-37 T 29-03-2018 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 6.1E-77 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 667 867 4.3E-35 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1056 13.211 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Gene3D G3DSA:3.40.50.20 4 117 1.1E-38 T 29-03-2018 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1047 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05230 3c3f34bf9c3e6586c2151b8ee4bc56ba 1058 Gene3D G3DSA:3.40.50.1380 928 1058 1.2E-30 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 SUPERFAMILY SSF54211 421 537 1.02E-20 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Gene3D G3DSA:3.40.50.300 73 237 1.5E-28 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Gene3D G3DSA:3.30.230.10 439 547 1.0E-17 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Gene3D G3DSA:3.40.50.300 2 72 4.0E-9 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 SUPERFAMILY SSF54980 347 423 2.99E-16 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR00315 GTP-binding elongation factor signature 76 86 2.0E-18 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR00315 GTP-binding elongation factor signature 56 64 2.0E-18 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR00315 GTP-binding elongation factor signature 92 103 2.0E-18 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR00315 GTP-binding elongation factor signature 10 23 2.0E-18 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR00315 GTP-binding elongation factor signature 128 137 2.0E-18 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 49 64 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Pfam PF03764 Elongation factor G, domain IV 421 536 1.3E-21 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Pfam PF00679 Elongation factor G C-terminus 539 620 8.7E-17 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 SUPERFAMILY SSF54980 540 621 1.15E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 SMART SM00838 539 626 0.0022 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Gene3D G3DSA:2.40.30.10 238 336 1.3E-12 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Gene3D G3DSA:3.30.70.240 548 622 2.8E-10 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 SMART SM00889 422 537 6.9E-12 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Pfam PF00009 Elongation factor Tu GTP binding domain 7 243 1.8E-58 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Gene3D G3DSA:3.30.70.870 342 438 7.5E-17 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 Pfam PF14492 Elongation Factor G, domain II 347 419 9.7E-13 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 SUPERFAMILY SSF52540 7 241 5.21E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 475 497 3.1E-78 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 509 526 3.1E-78 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 460 474 3.1E-78 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 218 240 3.1E-78 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 114 137 3.1E-78 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 272 298 3.1E-78 T 29-03-2018 SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 SUPERFAMILY SSF50447 228 322 6.42E-15 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS11005 326573e881b953f0506f3ad6960e6481 646 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 163 6.1E-41 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS02305 310b14215b7c627bdb8154d67ddf07e8 319 Gene3D G3DSA:3.30.420.10 152 316 4.3E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS02305 310b14215b7c627bdb8154d67ddf07e8 319 SUPERFAMILY SSF53098 160 311 9.1E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS02305 310b14215b7c627bdb8154d67ddf07e8 319 Gene3D G3DSA:1.10.10.60 3 43 8.6E-7 T 29-03-2018 SPSF3K_RS03920 310b14215b7c627bdb8154d67ddf07e8 319 Gene3D G3DSA:3.30.420.10 152 316 4.3E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS03920 310b14215b7c627bdb8154d67ddf07e8 319 SUPERFAMILY SSF53098 160 311 9.1E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS03920 310b14215b7c627bdb8154d67ddf07e8 319 Gene3D G3DSA:1.10.10.60 3 43 8.6E-7 T 29-03-2018 SPSF3K_RS04855 310b14215b7c627bdb8154d67ddf07e8 319 Gene3D G3DSA:3.30.420.10 152 316 4.3E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS04855 310b14215b7c627bdb8154d67ddf07e8 319 SUPERFAMILY SSF53098 160 311 9.1E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS04855 310b14215b7c627bdb8154d67ddf07e8 319 Gene3D G3DSA:1.10.10.60 3 43 8.6E-7 T 29-03-2018 SPSF3K_RS09275 310b14215b7c627bdb8154d67ddf07e8 319 Gene3D G3DSA:3.30.420.10 152 316 4.3E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS09275 310b14215b7c627bdb8154d67ddf07e8 319 SUPERFAMILY SSF53098 160 311 9.1E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS09275 310b14215b7c627bdb8154d67ddf07e8 319 Gene3D G3DSA:1.10.10.60 3 43 8.6E-7 T 29-03-2018 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 9.9E-250 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 PRINTS PR00298 60kDa chaperonin signature 348 373 9.6E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 PRINTS PR00298 60kDa chaperonin signature 396 417 9.6E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 PRINTS PR00298 60kDa chaperonin signature 26 52 9.6E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 PRINTS PR00298 60kDa chaperonin signature 82 109 9.6E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 PRINTS PR00298 60kDa chaperonin signature 266 289 9.6E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 521 1.6E-103 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 SUPERFAMILY SSF52029 182 374 2.39E-82 T 29-03-2018 IPR027409 GroEL-like apical domain SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 Gene3D G3DSA:1.10.560.10 372 513 4.1E-27 T 29-03-2018 IPR027413 GroEL-like equatorial domain SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 Gene3D G3DSA:1.10.560.10 1 185 5.2E-43 T 29-03-2018 IPR027413 GroEL-like equatorial domain SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 SUPERFAMILY SSF54849 136 204 4.81E-26 T 29-03-2018 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 Gene3D G3DSA:3.50.7.10 186 371 7.4E-95 T 29-03-2018 IPR027409 GroEL-like apical domain SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 541 40.676 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 SUPERFAMILY SSF48592 6 133 3.16E-78 T 29-03-2018 SPSF3K_RS00675 e0c2881589c29616057ecd677fa4b1e3 542 SUPERFAMILY SSF48592 404 518 3.16E-78 T 29-03-2018 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 SUPERFAMILY SSF48163 301 480 5.1E-40 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 Gene3D G3DSA:3.40.50.620 1 142 3.8E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 481 31.757 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 5.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 5.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 5.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 206 5.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 212 220 5.3E-28 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 SUPERFAMILY SSF52374 5 319 4.02E-102 T 29-03-2018 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 Gene3D G3DSA:1.10.1160.10 250 336 1.1E-29 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 326 1.9E-112 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 Gene3D G3DSA:1.10.10.350 381 481 4.3E-26 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 479 1.4E-166 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 SPSF3K_RS00985 d033137f960e33f458e6d7c30b7dd4cd 481 Gene3D G3DSA:3.40.50.620 143 248 1.2E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS06795 13fb57dd312dc84e0dfe8a36adeaa39d 111 Gene3D G3DSA:1.10.287.1080 4 103 1.9E-13 T 29-03-2018 SPSF3K_RS06795 13fb57dd312dc84e0dfe8a36adeaa39d 111 SUPERFAMILY SSF101386 6 96 1.8E-15 T 29-03-2018 SPSF3K_RS06795 13fb57dd312dc84e0dfe8a36adeaa39d 111 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 85 8.9E-7 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core SPSF3K_RS00095 c1089b73a3bd8c07c2bd1d497ff5b2cc 280 Pfam PF00005 ABC transporter 25 174 1.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00095 c1089b73a3bd8c07c2bd1d497ff5b2cc 280 Gene3D G3DSA:3.40.50.300 1 253 4.6E-66 T 29-03-2018 SPSF3K_RS00095 c1089b73a3bd8c07c2bd1d497ff5b2cc 280 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 278 5.6E-120 T 29-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 SPSF3K_RS00095 c1089b73a3bd8c07c2bd1d497ff5b2cc 280 SUPERFAMILY SSF52540 3 237 2.35E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00095 c1089b73a3bd8c07c2bd1d497ff5b2cc 280 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS00095 c1089b73a3bd8c07c2bd1d497ff5b2cc 280 SMART SM00382 32 222 7.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 2.9E-42 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 Gene3D G3DSA:3.40.50.2300 167 263 2.3E-37 T 29-03-2018 SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 SUPERFAMILY SSF52794 168 267 4.19E-35 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 169 252 2.6E-29 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 147 9.2E-37 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 Pfam PF02378 Phosphotransferase system, EIIC 297 593 1.7E-22 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 SUPERFAMILY SSF55804 1 147 6.28E-43 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 Gene3D G3DSA:3.40.930.10 1 161 3.1E-43 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 170 258 1.3E-15 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS05325 7a6b8f7670b9d617d3aa614600fb8b75 649 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 278 645 2.5E-115 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS10640 2ad73b348fdeaaa6e127adebf6b22752 337 Gene3D G3DSA:3.40.718.10 1 332 3.2E-102 T 29-03-2018 SPSF3K_RS10640 2ad73b348fdeaaa6e127adebf6b22752 337 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 3 332 1.1E-119 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 SPSF3K_RS10640 2ad73b348fdeaaa6e127adebf6b22752 337 PIRSF PIRSF002465 1 335 1.6E-127 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 SPSF3K_RS10640 2ad73b348fdeaaa6e127adebf6b22752 337 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 335 145.992 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 SPSF3K_RS10640 2ad73b348fdeaaa6e127adebf6b22752 337 Pfam PF02504 Fatty acid synthesis protein 3 320 2.4E-107 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 SPSF3K_RS10640 2ad73b348fdeaaa6e127adebf6b22752 337 SUPERFAMILY SSF53659 1 330 5.76E-102 T 29-03-2018 SPSF3K_RS07890 888d95086f4e7c5b386f7411bf8284af 278 Gene3D G3DSA:3.40.50.720 1 266 6.1E-39 T 29-03-2018 SPSF3K_RS07890 888d95086f4e7c5b386f7411bf8284af 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 144 264 2.3E-20 T 29-03-2018 SPSF3K_RS07890 888d95086f4e7c5b386f7411bf8284af 278 Pfam PF00106 short chain dehydrogenase 3 131 5.3E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS07890 888d95086f4e7c5b386f7411bf8284af 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS07890 888d95086f4e7c5b386f7411bf8284af 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS07890 888d95086f4e7c5b386f7411bf8284af 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 1.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS07890 888d95086f4e7c5b386f7411bf8284af 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 1.5E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS07890 888d95086f4e7c5b386f7411bf8284af 278 SUPERFAMILY SSF51735 161 265 1.06E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS07890 888d95086f4e7c5b386f7411bf8284af 278 SUPERFAMILY SSF51735 2 131 1.06E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS01705 14f866066e1441df7414732a199e1c5e 431 Pfam PF02378 Phosphotransferase system, EIIC 29 359 1.4E-60 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS01705 14f866066e1441df7414732a199e1c5e 431 PIRSF PIRSF006351 1 430 2.6E-131 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS01705 14f866066e1441df7414732a199e1c5e 431 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 427 1.2E-129 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 Gene3D G3DSA:3.30.420.40 1 170 2.5E-66 T 29-03-2018 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 PRINTS PR00301 70kDa heat shock protein signature 112 132 5.8E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.8E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 PRINTS PR00301 70kDa heat shock protein signature 53 61 5.8E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 PRINTS PR00301 70kDa heat shock protein signature 304 320 5.8E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 PRINTS PR00301 70kDa heat shock protein signature 358 377 5.8E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 PRINTS PR00301 70kDa heat shock protein signature 172 182 5.8E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 PRINTS PR00301 70kDa heat shock protein signature 439 455 5.8E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 PRINTS PR00301 70kDa heat shock protein signature 335 355 5.8E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.8E-78 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 SUPERFAMILY SSF100920 354 510 6.02E-60 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 Gene3D G3DSA:2.60.34.10 360 501 2.0E-64 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 612 36.053 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 SUPERFAMILY SSF53067 1 157 4.61E-56 T 29-03-2018 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 SUPERFAMILY SSF53067 161 351 4.63E-66 T 29-03-2018 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 Gene3D G3DSA:1.20.1270.10 502 588 1.9E-16 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 9.6E-282 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 Gene3D G3DSA:3.30.420.40 171 331 1.0E-46 T 29-03-2018 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 SUPERFAMILY SSF100934 477 576 2.22E-11 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 Pfam PF00012 Hsp70 protein 76 574 9.9E-217 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS10130 cacb2b4157c9754d60d39e5df23efa70 612 Pfam PF00012 Hsp70 protein 4 74 7.2E-25 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 SPSF3K_RS06690 71ed81c785aadd1e2abdc3e897e46f2f 200 Gene3D G3DSA:3.40.50.360 1 179 3.2E-29 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS06690 71ed81c785aadd1e2abdc3e897e46f2f 200 Pfam PF03358 NADPH-dependent FMN reductase 1 147 5.3E-33 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SPSF3K_RS06690 71ed81c785aadd1e2abdc3e897e46f2f 200 SUPERFAMILY SSF52218 1 173 7.84E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS03215 33ed6b9066924a6fd2376b413cba9cc5 237 Pfam PF02527 rRNA small subunit methyltransferase G 21 192 1.4E-49 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SPSF3K_RS03215 33ed6b9066924a6fd2376b413cba9cc5 237 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 202 1.9E-49 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SPSF3K_RS03215 33ed6b9066924a6fd2376b413cba9cc5 237 SUPERFAMILY SSF53335 1 237 2.48E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS03215 33ed6b9066924a6fd2376b413cba9cc5 237 PIRSF PIRSF003078 1 220 1.0E-52 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SPSF3K_RS03215 33ed6b9066924a6fd2376b413cba9cc5 237 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 215 26.952 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SPSF3K_RS03215 33ed6b9066924a6fd2376b413cba9cc5 237 Gene3D G3DSA:3.40.50.150 4 237 7.4E-33 T 29-03-2018 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 SUPERFAMILY SSF55347 152 315 4.76E-65 T 29-03-2018 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 314 3.4E-61 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 Gene3D G3DSA:3.40.50.720 1 161 5.4E-68 T 29-03-2018 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 4.4E-31 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 231 248 4.4E-31 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 267 282 4.4E-31 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 4.4E-31 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 4.4E-31 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 SMART SM00846 3 152 4.4E-80 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 SUPERFAMILY SSF51735 3 168 1.53E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 Gene3D G3DSA:3.30.360.10 162 316 1.5E-60 T 29-03-2018 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 PIRSF PIRSF000149 1 336 5.2E-112 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 2.7E-35 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS01205 85c9b932feb4e969b2e43a4c76e19a54 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 1.3E-129 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS03120 fdbce74555979407ac50bb787c32e51a 175 SUPERFAMILY SSF56784 14 150 7.07E-26 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS03120 fdbce74555979407ac50bb787c32e51a 175 Pfam PF13419 Haloacid dehalogenase-like hydrolase 49 137 4.2E-12 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS03120 fdbce74555979407ac50bb787c32e51a 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 30 139 1.7E-16 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 SPSF3K_RS03120 fdbce74555979407ac50bb787c32e51a 175 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 7 167 3.5E-33 T 29-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like SPSF3K_RS03120 fdbce74555979407ac50bb787c32e51a 175 Gene3D G3DSA:3.40.50.1000 16 167 3.5E-23 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS10465 5c325283cd4743a7bc8217b570fced52 101 SUPERFAMILY SSF50104 2 99 3.31E-31 T 29-03-2018 IPR008991 Translation protein SH3-like domain SPSF3K_RS10465 5c325283cd4743a7bc8217b570fced52 101 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 94 19.855 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10465 5c325283cd4743a7bc8217b570fced52 101 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10465 5c325283cd4743a7bc8217b570fced52 101 Pfam PF00467 KOW motif 5 36 1.4E-6 T 29-03-2018 IPR005824 KOW SPSF3K_RS10465 5c325283cd4743a7bc8217b570fced52 101 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 99 1.3E-24 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10465 5c325283cd4743a7bc8217b570fced52 101 SMART SM00739 2 29 6.4E-6 T 29-03-2018 IPR005824 KOW SPSF3K_RS10465 5c325283cd4743a7bc8217b570fced52 101 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 99 2.6E-34 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10465 5c325283cd4743a7bc8217b570fced52 101 Gene3D G3DSA:2.30.30.30 1 90 9.8E-29 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 641 34.458 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 Gene3D G3DSA:3.40.50.800 538 647 1.6E-28 T 29-03-2018 IPR004154 Anticodon-binding SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 Gene3D G3DSA:3.30.980.10 69 227 1.5E-41 T 29-03-2018 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 SUPERFAMILY SSF81271 2 61 5.45E-16 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 SUPERFAMILY SSF55681 242 532 3.38E-98 T 29-03-2018 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 SUPERFAMILY SSF52954 533 637 9.36E-33 T 29-03-2018 IPR004154 Anticodon-binding SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 1.2E-46 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 513 526 1.2E-46 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 540 552 1.2E-46 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 498 1.2E-46 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 1.2E-46 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 SUPERFAMILY SSF55186 64 240 4.71E-62 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 637 8.9E-231 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 325 535 2.8E-34 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 Gene3D G3DSA:3.10.20.30 1 63 1.3E-19 T 29-03-2018 IPR012675 Beta-grasp domain SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 SMART SM00863 169 218 1.7E-23 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 1.6E-15 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 Pfam PF03129 Anticodon binding domain 547 636 2.1E-23 T 29-03-2018 IPR004154 Anticodon-binding SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 Pfam PF02824 TGS domain 2 61 1.8E-10 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 SPSF3K_RS04080 7b43fa774ee747e5cd70b01137298ea0 648 Gene3D G3DSA:3.30.930.10 228 537 3.1E-109 T 29-03-2018 SPSF3K_RS03030 2f8ca56678b000580e8138dcc65e1ffd 408 Pfam PF00266 Aminotransferase class-V 24 393 1.1E-153 T 29-03-2018 IPR000192 Aminotransferase class V domain SPSF3K_RS03030 2f8ca56678b000580e8138dcc65e1ffd 408 Gene3D G3DSA:3.90.1150.10 280 400 6.6E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS03030 2f8ca56678b000580e8138dcc65e1ffd 408 SUPERFAMILY SSF53383 5 400 9.14E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS03030 2f8ca56678b000580e8138dcc65e1ffd 408 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 214 233 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SPSF3K_RS03030 2f8ca56678b000580e8138dcc65e1ffd 408 Gene3D G3DSA:3.40.640.10 32 279 1.3E-59 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS03030 2f8ca56678b000580e8138dcc65e1ffd 408 PIRSF PIRSF005572 21 405 9.7E-50 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SPSF3K_RS03030 2f8ca56678b000580e8138dcc65e1ffd 408 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 6 404 8.4E-183 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SPSF3K_RS03905 8bf1e212638f70fca7f246398e03240f 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 6 277 3.4E-106 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS03905 8bf1e212638f70fca7f246398e03240f 299 Hamap MF_00367 GTPase Era [era]. 3 294 38.037 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS03905 8bf1e212638f70fca7f246398e03240f 299 SUPERFAMILY SSF54814 178 295 2.91E-43 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SPSF3K_RS03905 8bf1e212638f70fca7f246398e03240f 299 Pfam PF01926 50S ribosome-binding GTPase 8 122 3.1E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS03905 8bf1e212638f70fca7f246398e03240f 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 165 6.6E-32 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS03905 8bf1e212638f70fca7f246398e03240f 299 Gene3D G3DSA:3.40.50.300 7 195 2.5E-36 T 29-03-2018 SPSF3K_RS03905 8bf1e212638f70fca7f246398e03240f 299 Pfam PF07650 KH domain 205 283 1.2E-23 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS03905 8bf1e212638f70fca7f246398e03240f 299 Gene3D G3DSA:3.30.300.20 196 297 2.1E-46 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS03905 8bf1e212638f70fca7f246398e03240f 299 SUPERFAMILY SSF52540 8 202 2.0E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 22 39 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 Pfam PF00367 phosphotransferase system, EIIB 11 44 3.1E-14 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 Gene3D G3DSA:3.30.1360.60 7 83 6.3E-29 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 Pfam PF02378 Phosphotransferase system, EIIC 113 400 1.4E-29 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 555 567 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 6 636 2.4E-208 T 29-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 SUPERFAMILY SSF51261 485 637 1.96E-56 T 29-03-2018 IPR011055 Duplicated hybrid motif SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 493 613 2.0E-47 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 Gene3D G3DSA:2.70.70.10 480 639 4.5E-61 T 29-03-2018 SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 492 615 4.9E-53 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS06170 fc5fa52bce4108e3712600f2171bf91c 639 SUPERFAMILY SSF55604 8 84 4.32E-23 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS01195 f20d03fc4c6688782215f38aa727a4d6 156 PIRSF PIRSF002122 1 156 1.1E-56 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 SPSF3K_RS01195 f20d03fc4c6688782215f38aa727a4d6 156 Gene3D G3DSA:1.10.455.10 6 156 7.3E-60 T 29-03-2018 IPR023798 Ribosomal protein S7 domain SPSF3K_RS01195 f20d03fc4c6688782215f38aa727a4d6 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.2E-68 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SPSF3K_RS01195 f20d03fc4c6688782215f38aa727a4d6 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS01195 f20d03fc4c6688782215f38aa727a4d6 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.392 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SPSF3K_RS01195 f20d03fc4c6688782215f38aa727a4d6 156 SUPERFAMILY SSF47973 1 149 9.55E-60 T 29-03-2018 IPR023798 Ribosomal protein S7 domain SPSF3K_RS01195 f20d03fc4c6688782215f38aa727a4d6 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 8.0E-66 T 29-03-2018 IPR023798 Ribosomal protein S7 domain SPSF3K_RS02345 e6c0c49114087e5fccbb417ca1be0ad7 106 SUPERFAMILY SSF46785 6 98 1.16E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02345 e6c0c49114087e5fccbb417ca1be0ad7 106 Gene3D G3DSA:1.10.10.10 1 92 7.8E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02345 e6c0c49114087e5fccbb417ca1be0ad7 106 Pfam PF03551 Transcriptional regulator PadR-like family 18 83 3.8E-13 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Gene3D G3DSA:1.10.460.10 463 578 1.4E-28 T 29-03-2018 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Gene3D G3DSA:2.70.20.10 350 462 5.0E-37 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 SUPERFAMILY SSF57783 590 630 3.91E-13 T 29-03-2018 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 SMART SM00437 266 527 1.8E-107 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 303 326 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Hamap MF_00952 DNA topoisomerase 1 [topA]. 27 650 54.97 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 SUPERFAMILY SSF56712 27 606 1.03E-191 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Gene3D G3DSA:3.40.50.140 26 153 1.4E-38 T 29-03-2018 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Pfam PF01131 DNA topoisomerase 152 565 3.5E-131 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 317 326 1.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 101 114 1.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 1.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 393 409 1.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 490 504 1.3E-35 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Gene3D G3DSA:1.10.460.10 159 349 4.9E-47 T 29-03-2018 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 SMART SM00493 27 127 3.4E-28 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 SMART SM00436 128 216 6.0E-52 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 674 707 0.84 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 634 670 2.5E-12 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 595 630 3.1E-14 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Gene3D G3DSA:3.30.65.10 671 711 0.0033 T 29-03-2018 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Gene3D G3DSA:3.30.65.10 579 630 2.8E-16 T 29-03-2018 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Gene3D G3DSA:3.30.65.10 631 670 3.7E-9 T 29-03-2018 SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 Pfam PF01751 Toprim domain 29 137 5.8E-30 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS06860 0182ef4b2c5b7c12345cefe66f7e49c9 711 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 29 628 4.3E-242 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 SPSF3K_RS00785 fa6c7bf3520d126b3c2c6fa6d8acdac0 297 Gene3D G3DSA:3.40.50.10330 1 135 8.6E-32 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SPSF3K_RS00785 fa6c7bf3520d126b3c2c6fa6d8acdac0 297 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 127 5.3E-31 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPSF3K_RS00785 fa6c7bf3520d126b3c2c6fa6d8acdac0 297 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 293 1.3E-65 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase SPSF3K_RS00785 fa6c7bf3520d126b3c2c6fa6d8acdac0 297 SUPERFAMILY SSF111331 1 294 8.72E-72 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SPSF3K_RS00785 fa6c7bf3520d126b3c2c6fa6d8acdac0 297 SMART SM00046 3 131 2.5E-10 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 409 2.0E-125 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 ProSitePatterns PS00099 Thiolases active site. 392 405 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 PIRSF PIRSF000429 4 412 1.9E-113 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 Pfam PF02803 Thiolase, C-terminal domain 281 409 8.3E-41 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 Gene3D G3DSA:3.40.47.10 280 408 6.0E-21 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 Gene3D G3DSA:3.40.47.10 1 279 4.2E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 SUPERFAMILY SSF53901 9 280 1.86E-66 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 SUPERFAMILY SSF53901 282 409 2.61E-34 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 Pfam PF00108 Thiolase, N-terminal domain 9 272 1.0E-72 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SPSF3K_RS00235 44cb5ab90b3a2b6c622f6414aefb3427 416 ProSitePatterns PS00737 Thiolases signature 2. 356 372 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SPSF3K_RS03350 3af67db9e4184cb5d96fff31e84d766d 252 Gene3D G3DSA:1.10.443.10 102 252 2.4E-14 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS03350 3af67db9e4184cb5d96fff31e84d766d 252 SUPERFAMILY SSF56349 12 250 3.83E-17 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPSF3K_RS03350 3af67db9e4184cb5d96fff31e84d766d 252 Pfam PF00589 Phage integrase family 117 251 2.6E-9 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS03350 3af67db9e4184cb5d96fff31e84d766d 252 Hamap MF_01817 Tyrosine recombinase XerD-like. 5 250 32.877 T 29-03-2018 IPR020876 Tyrosine recombinase XerD-like GO:0005737 SPSF3K_RS03350 3af67db9e4184cb5d96fff31e84d766d 252 Gene3D G3DSA:1.10.150.130 1 86 6.2E-7 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SPSF3K_RS08030 03f445a933eda2970f877cc35992c615 554 SUPERFAMILY SSF56281 4 419 3.05E-69 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08030 03f445a933eda2970f877cc35992c615 554 Hamap MF_01491 Ribonuclease J [rnj]. 1 552 39.052 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SPSF3K_RS08030 03f445a933eda2970f877cc35992c615 554 Pfam PF00753 Metallo-beta-lactamase superfamily 16 165 1.5E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08030 03f445a933eda2970f877cc35992c615 554 Gene3D G3DSA:3.60.15.10 1 445 3.5E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08030 03f445a933eda2970f877cc35992c615 554 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 353 404 2.4E-10 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain SPSF3K_RS08030 03f445a933eda2970f877cc35992c615 554 SMART SM00849 16 212 5.3E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08030 03f445a933eda2970f877cc35992c615 554 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 4 550 1.6E-151 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 SPSF3K_RS00075 7272a508114a2e8aab5fd313f32f32e2 426 SUPERFAMILY SSF63411 11 231 1.07E-35 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPSF3K_RS00075 7272a508114a2e8aab5fd313f32f32e2 426 Gene3D G3DSA:3.30.830.10 6 222 1.1E-42 T 29-03-2018 SPSF3K_RS00075 7272a508114a2e8aab5fd313f32f32e2 426 Gene3D G3DSA:3.30.830.10 223 424 6.2E-13 T 29-03-2018 SPSF3K_RS00075 7272a508114a2e8aab5fd313f32f32e2 426 SUPERFAMILY SSF63411 256 415 1.15E-9 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPSF3K_RS00075 7272a508114a2e8aab5fd313f32f32e2 426 Pfam PF05193 Peptidase M16 inactive domain 184 360 5.7E-14 T 29-03-2018 IPR007863 Peptidase M16, C-terminal SPSF3K_RS00075 7272a508114a2e8aab5fd313f32f32e2 426 Pfam PF00675 Insulinase (Peptidase family M16) 61 173 2.2E-12 T 29-03-2018 IPR011765 Peptidase M16, N-terminal SPSF3K_RS01970 adc34d8eeac8cd9d8dd5ca9cc17f4f19 318 PIRSF PIRSF026567 1 317 1.0E-107 T 29-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted SPSF3K_RS01970 adc34d8eeac8cd9d8dd5ca9cc17f4f19 318 SUPERFAMILY SSF53335 41 292 8.52E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS01970 adc34d8eeac8cd9d8dd5ca9cc17f4f19 318 Pfam PF02384 N-6 DNA Methylase 78 310 9.0E-7 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SPSF3K_RS01970 adc34d8eeac8cd9d8dd5ca9cc17f4f19 318 Gene3D G3DSA:3.40.50.150 88 315 1.4E-26 T 29-03-2018 SPSF3K_RS10015 556b92c58b79e44fbd07ca1cb58aa5cf 486 Pfam PF00860 Permease family 171 445 5.7E-23 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPSF3K_RS10015 556b92c58b79e44fbd07ca1cb58aa5cf 486 Pfam PF00860 Permease family 17 164 2.2E-15 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPSF3K_RS10015 556b92c58b79e44fbd07ca1cb58aa5cf 486 PIRSF PIRSF005353 1 485 6.6E-162 T 29-03-2018 IPR026033 Purine permease PbuG-like SPSF3K_RS06270 65759e187593f392a93b1fbf4d2ba8d0 223 SUPERFAMILY SSF81301 3 198 3.6E-58 T 29-03-2018 SPSF3K_RS06270 65759e187593f392a93b1fbf4d2ba8d0 223 Gene3D G3DSA:3.30.460.10 2 146 4.1E-38 T 29-03-2018 SPSF3K_RS06270 65759e187593f392a93b1fbf4d2ba8d0 223 Gene3D G3DSA:1.10.287.860 148 196 1.9E-18 T 29-03-2018 SPSF3K_RS06270 65759e187593f392a93b1fbf4d2ba8d0 223 Pfam PF04607 Region found in RelA / SpoT proteins 44 163 6.5E-38 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 SPSF3K_RS06270 65759e187593f392a93b1fbf4d2ba8d0 223 SMART SM00954 44 165 3.6E-44 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 SUPERFAMILY SSF53738 166 256 1.45E-22 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 6.4E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 6.4E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 6.4E-13 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 Gene3D G3DSA:3.30.310.50 374 448 4.2E-20 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 SUPERFAMILY SSF53738 3 179 4.71E-43 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 SUPERFAMILY SSF55957 357 447 6.02E-24 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 365 2.4E-32 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 43.762 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 2.2E-191 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 SUPERFAMILY SSF53738 257 365 5.89E-31 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 Gene3D G3DSA:3.40.120.10 263 373 1.1E-31 T 29-03-2018 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 Gene3D G3DSA:3.40.120.10 151 262 2.1E-21 T 29-03-2018 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 443 2.4E-16 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 136 1.3E-42 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 166 253 2.0E-13 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPSF3K_RS07965 e14ebc49d9e50c24a0d57d78200cb145 450 Gene3D G3DSA:3.40.120.10 1 150 1.6E-44 T 29-03-2018 SPSF3K_RS08645 f60910a42db0b7eea9621702345007b4 234 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 233 2.1E-75 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 SPSF3K_RS08645 f60910a42db0b7eea9621702345007b4 234 SUPERFAMILY SSF100950 1 233 1.64E-82 T 29-03-2018 SPSF3K_RS08645 f60910a42db0b7eea9621702345007b4 234 Gene3D G3DSA:3.40.50.1360 1 234 5.3E-64 T 29-03-2018 SPSF3K_RS08645 f60910a42db0b7eea9621702345007b4 234 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 233 41.291 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 SPSF3K_RS08645 f60910a42db0b7eea9621702345007b4 234 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 20 219 2.3E-16 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 SPSF3K_RS08810 c93da8f90fed8c7ba298137d1522267c 275 PIRSF PIRSF005578 1 268 3.0E-97 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 SPSF3K_RS08810 c93da8f90fed8c7ba298137d1522267c 275 SUPERFAMILY SSF53335 60 253 4.65E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS08810 c93da8f90fed8c7ba298137d1522267c 275 SUPERFAMILY SSF55174 3 71 5.45E-8 T 29-03-2018 SPSF3K_RS08810 c93da8f90fed8c7ba298137d1522267c 275 Gene3D G3DSA:3.40.50.150 65 275 1.6E-58 T 29-03-2018 SPSF3K_RS08810 c93da8f90fed8c7ba298137d1522267c 275 Gene3D G3DSA:3.10.290.10 1 64 1.8E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08810 c93da8f90fed8c7ba298137d1522267c 275 Pfam PF01728 FtsJ-like methyltransferase 62 241 1.3E-17 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 SPSF3K_RS08810 c93da8f90fed8c7ba298137d1522267c 275 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 239 2.1E-80 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 SPSF3K_RS03820 d558d4a664957a768d741b05a01f1275 802 Pfam PF01580 FtsK/SpoIIIE family 443 635 2.4E-57 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SPSF3K_RS03820 d558d4a664957a768d741b05a01f1275 802 Pfam PF09397 Ftsk gamma domain 740 800 9.7E-28 T 29-03-2018 IPR018541 FtsK gamma domain SPSF3K_RS03820 d558d4a664957a768d741b05a01f1275 802 SUPERFAMILY SSF46785 738 801 2.52E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03820 d558d4a664957a768d741b05a01f1275 802 SUPERFAMILY SSF52540 413 707 4.58E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03820 d558d4a664957a768d741b05a01f1275 802 Gene3D G3DSA:3.40.50.300 193 773 2.7E-50 T 29-03-2018 SPSF3K_RS03820 d558d4a664957a768d741b05a01f1275 802 SMART SM00843 738 802 2.8E-33 T 29-03-2018 IPR018541 FtsK gamma domain SPSF3K_RS03820 d558d4a664957a768d741b05a01f1275 802 SMART SM00382 474 656 6.3E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08765 1bcee1785b970c500e2b591e0fbd817a 311 Gene3D G3DSA:3.20.20.70 2 310 4.6E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS08765 1bcee1785b970c500e2b591e0fbd817a 311 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 244 264 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 SPSF3K_RS08765 1bcee1785b970c500e2b591e0fbd817a 311 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 307 28.559 T 29-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 SPSF3K_RS08765 1bcee1785b970c500e2b591e0fbd817a 311 SUPERFAMILY SSF51395 1 308 1.21E-67 T 29-03-2018 SPSF3K_RS08765 1bcee1785b970c500e2b591e0fbd817a 311 Pfam PF01180 Dihydroorotate dehydrogenase 5 292 1.9E-78 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 SPSF3K_RS08765 1bcee1785b970c500e2b591e0fbd817a 311 PIRSF PIRSF000164 1 309 6.1E-64 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 SPSF3K_RS08765 1bcee1785b970c500e2b591e0fbd817a 311 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 305 1.1E-53 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 SPSF3K_RS03130 2c9772e000eb6e3cd98959b67cd64e02 103 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 2.2E-20 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SPSF3K_RS03130 2c9772e000eb6e3cd98959b67cd64e02 103 SMART SM01103 2 85 9.0E-34 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SPSF3K_RS03130 2c9772e000eb6e3cd98959b67cd64e02 103 Gene3D G3DSA:3.30.110.60 1 96 7.9E-25 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SPSF3K_RS03130 2c9772e000eb6e3cd98959b67cd64e02 103 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 96 8.0E-40 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SPSF3K_RS03130 2c9772e000eb6e3cd98959b67cd64e02 103 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 1.3E-25 T 29-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 SPSF3K_RS03130 2c9772e000eb6e3cd98959b67cd64e02 103 SUPERFAMILY SSF75471 1 95 1.05E-26 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 SPSF3K_RS00195 4946d436ddf24624e6845760b7b5a0ba 303 Pfam PF13349 Putative adhesin 56 300 1.1E-23 T 29-03-2018 IPR025164 Putative adhesin SPSF3K_RS10870 ea17dcd1840166520144c73153b433cb 123 Pfam PF04977 Septum formation initiator 42 118 7.3E-21 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SPSF3K_RS07655 75d31858c67871c0d9a3df27938ce93e 230 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 225 1.5E-57 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS07655 75d31858c67871c0d9a3df27938ce93e 230 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 229 39.198 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS07655 75d31858c67871c0d9a3df27938ce93e 230 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 223 1.8E-44 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS07655 75d31858c67871c0d9a3df27938ce93e 230 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 58 71 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS07655 75d31858c67871c0d9a3df27938ce93e 230 Gene3D G3DSA:3.20.20.70 1 229 1.4E-55 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS07655 75d31858c67871c0d9a3df27938ce93e 230 SUPERFAMILY SSF51366 2 228 3.6E-67 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SPSF3K_RS07655 75d31858c67871c0d9a3df27938ce93e 230 SMART SM00934 5 224 2.0E-88 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS08875 448f415e0f866c7a0ed33487b8d700fe 149 SUPERFAMILY SSF55811 11 146 3.66E-29 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPSF3K_RS08875 448f415e0f866c7a0ed33487b8d700fe 149 PRINTS PR00502 NUDIX hydrolase family signature 43 57 9.9E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SPSF3K_RS08875 448f415e0f866c7a0ed33487b8d700fe 149 PRINTS PR00502 NUDIX hydrolase family signature 57 72 9.9E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SPSF3K_RS08875 448f415e0f866c7a0ed33487b8d700fe 149 Pfam PF00293 NUDIX domain 18 142 1.7E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SPSF3K_RS08875 448f415e0f866c7a0ed33487b8d700fe 149 Gene3D G3DSA:3.90.79.10 1 148 3.4E-23 T 29-03-2018 SPSF3K_RS08875 448f415e0f866c7a0ed33487b8d700fe 149 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 SUPERFAMILY SSF48179 205 372 2.86E-41 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 Gene3D G3DSA:1.10.1040.10 208 381 3.4E-37 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 153 165 - T 29-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 SUPERFAMILY SSF51735 3 200 1.89E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 2 379 41.592 T 29-03-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 PRINTS PR00084 Mannitol dehydrogenase signature 117 130 3.6E-21 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 PRINTS PR00084 Mannitol dehydrogenase signature 4 14 3.6E-21 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 PRINTS PR00084 Mannitol dehydrogenase signature 153 166 3.6E-21 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 PRINTS PR00084 Mannitol dehydrogenase signature 171 186 3.6E-21 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 Gene3D G3DSA:3.40.50.720 27 202 2.9E-30 T 29-03-2018 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 3 126 4.0E-27 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 SPSF3K_RS07230 9c24879448311072fbaabe550dc9af65 381 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 153 373 5.0E-64 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 Pfam PF01131 DNA topoisomerase 157 559 2.0E-101 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 SUPERFAMILY SSF56712 2 570 3.66E-137 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 Gene3D G3DSA:2.70.20.10 350 456 9.3E-21 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 SMART SM00493 2 126 2.7E-18 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 304 318 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 Pfam PF01751 Toprim domain 4 136 3.0E-20 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 Gene3D G3DSA:1.10.460.10 159 349 4.4E-32 T 29-03-2018 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 SMART SM00436 128 227 3.3E-24 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 SMART SM00437 267 522 2.1E-49 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 Gene3D G3DSA:1.10.460.10 457 573 2.6E-16 T 29-03-2018 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.9E-19 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 197 215 1.9E-19 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 483 497 1.9E-19 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 309 318 1.9E-19 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05565 4c7372cca0b6c1074c04df9292c7c728 574 Gene3D G3DSA:3.40.50.140 2 156 1.2E-37 T 29-03-2018 SPSF3K_RS03185 1a1269442aaaa7ec78ee2a0894347682 281 Pfam PF03180 NLPA lipoprotein 32 281 2.7E-86 T 29-03-2018 IPR004872 Lipoprotein NlpA family SPSF3K_RS03185 1a1269442aaaa7ec78ee2a0894347682 281 Gene3D G3DSA:3.40.190.10 31 133 1.1E-20 T 29-03-2018 SPSF3K_RS03185 1a1269442aaaa7ec78ee2a0894347682 281 Gene3D G3DSA:3.40.190.10 135 281 2.7E-39 T 29-03-2018 SPSF3K_RS03185 1a1269442aaaa7ec78ee2a0894347682 281 SUPERFAMILY SSF53850 31 281 3.99E-70 T 29-03-2018 SPSF3K_RS03185 1a1269442aaaa7ec78ee2a0894347682 281 PIRSF PIRSF002854 1 281 1.6E-76 T 29-03-2018 IPR004872 Lipoprotein NlpA family SPSF3K_RS03625 d18ea6d4631d1892e7e779e4dc54a54b 236 PIRSF PIRSF039137 1 236 5.3E-109 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 SPSF3K_RS03625 d18ea6d4631d1892e7e779e4dc54a54b 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS03625 d18ea6d4631d1892e7e779e4dc54a54b 236 Gene3D G3DSA:3.40.50.300 1 236 3.8E-58 T 29-03-2018 SPSF3K_RS03625 d18ea6d4631d1892e7e779e4dc54a54b 236 SUPERFAMILY SSF52540 3 234 2.11E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03625 d18ea6d4631d1892e7e779e4dc54a54b 236 SMART SM00382 28 215 3.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS03625 d18ea6d4631d1892e7e779e4dc54a54b 236 Pfam PF00005 ABC transporter 19 164 3.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS06250 fca0d18163d405aa53bf2ab72e28ee91 115 SUPERFAMILY SSF160800 1 112 2.48E-42 T 29-03-2018 IPR014965 Putative amino acid metabolism SPSF3K_RS06250 fca0d18163d405aa53bf2ab72e28ee91 115 Gene3D G3DSA:3.30.1820.10 2 111 1.2E-42 T 29-03-2018 IPR014965 Putative amino acid metabolism SPSF3K_RS06250 fca0d18163d405aa53bf2ab72e28ee91 115 Pfam PF08866 Putative amino acid metabolism 1 110 1.3E-42 T 29-03-2018 IPR014965 Putative amino acid metabolism SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 Pfam PF07739 TipAS antibiotic-recognition domain 115 227 6.5E-26 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 Pfam PF13411 MerR HTH family regulatory protein 3 70 2.1E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 SMART SM00422 3 71 2.2E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 Gene3D G3DSA:1.10.1660.10 1 57 2.4E-20 T 29-03-2018 SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 SUPERFAMILY SSF46955 3 98 3.11E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 SUPERFAMILY SSF89082 142 229 1.7E-21 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 2.9E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 2.9E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 2.9E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 Gene3D G3DSA:1.10.490.50 148 230 2.3E-18 T 29-03-2018 SPSF3K_RS03165 2796166ba4983d076bb9e9672d277ebe 230 Gene3D G3DSA:1.10.1660.10 58 147 3.2E-7 T 29-03-2018 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 SUPERFAMILY SSF55060 154 266 2.88E-31 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 77 88 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 PIRSF PIRSF000676 1 287 5.2E-85 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 SUPERFAMILY SSF54211 1 141 4.55E-30 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 Hamap MF_00384 Homoserine kinase [thrB]. 1 285 31.515 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 Pfam PF08544 GHMP kinases C terminal 191 262 3.4E-9 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 Pfam PF00288 GHMP kinases N terminal domain 70 130 1.7E-12 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 TIGRFAM TIGR00191 thrB: homoserine kinase 3 286 2.3E-74 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 Gene3D G3DSA:3.30.70.890 152 287 1.6E-23 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 Gene3D G3DSA:3.30.230.10 1 151 1.8E-27 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 PRINTS PR00958 Homoserine kinase signature 118 131 4.3E-39 T 29-03-2018 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 PRINTS PR00958 Homoserine kinase signature 156 173 4.3E-39 T 29-03-2018 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 PRINTS PR00958 Homoserine kinase signature 8 23 4.3E-39 T 29-03-2018 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 PRINTS PR00958 Homoserine kinase signature 84 99 4.3E-39 T 29-03-2018 SPSF3K_RS06085 10e2f661ada3dca1d57fea038fefbf22 287 PRINTS PR00958 Homoserine kinase signature 236 251 4.3E-39 T 29-03-2018 SPSF3K_RS09345 64d13236b7acbee68ef36ab82b250df0 425 SUPERFAMILY SSF103473 8 412 9.42E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS09345 64d13236b7acbee68ef36ab82b250df0 425 Gene3D G3DSA:1.20.1250.20 4 202 2.6E-22 T 29-03-2018 SPSF3K_RS09345 64d13236b7acbee68ef36ab82b250df0 425 Gene3D G3DSA:1.20.1250.20 232 412 7.4E-17 T 29-03-2018 SPSF3K_RS09345 64d13236b7acbee68ef36ab82b250df0 425 Pfam PF07690 Major Facilitator Superfamily 14 335 1.2E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 Gene3D G3DSA:3.20.20.80 1 477 2.9E-152 T 29-03-2018 SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 372 380 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 432 6.3E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 6.3E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 6.3E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 6.3E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 303 317 6.3E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 SUPERFAMILY SSF51445 2 470 8.65E-162 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPSF3K_RS01360 47b04846a44819f433c6a73f39d160f6 478 Pfam PF00232 Glycosyl hydrolase family 1 2 475 6.1E-132 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS07705 2145f5f186ca13045a2d1c7a76c16033 183 Gene3D G3DSA:2.160.10.10 15 181 1.7E-29 T 29-03-2018 SPSF3K_RS07705 2145f5f186ca13045a2d1c7a76c16033 183 SUPERFAMILY SSF51161 60 172 1.23E-30 T 29-03-2018 IPR011004 Trimeric LpxA-like SPSF3K_RS07705 2145f5f186ca13045a2d1c7a76c16033 183 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 164 6.5E-10 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS05205 2ef4c6e63639fed3ecc67200ba2281fe 295 Gene3D G3DSA:3.10.290.10 5 65 3.0E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS05205 2ef4c6e63639fed3ecc67200ba2281fe 295 SUPERFAMILY SSF55174 10 95 7.06E-13 T 29-03-2018 SPSF3K_RS05205 2ef4c6e63639fed3ecc67200ba2281fe 295 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 128 142 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS05205 2ef4c6e63639fed3ecc67200ba2281fe 295 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 7 294 1.2E-95 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS05205 2ef4c6e63639fed3ecc67200ba2281fe 295 Pfam PF00849 RNA pseudouridylate synthase 83 235 3.9E-35 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS05205 2ef4c6e63639fed3ecc67200ba2281fe 295 Gene3D G3DSA:3.30.2350.10 73 295 4.4E-73 T 29-03-2018 SPSF3K_RS05205 2ef4c6e63639fed3ecc67200ba2281fe 295 SMART SM00363 10 69 7.5E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS05205 2ef4c6e63639fed3ecc67200ba2281fe 295 SUPERFAMILY SSF55120 67 294 3.08E-78 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS05205 2ef4c6e63639fed3ecc67200ba2281fe 295 Pfam PF01479 S4 domain 11 55 6.3E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 272 488 2.0E-52 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 248 5.7E-60 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 SUPERFAMILY SSF53850 268 488 3.51E-57 T 29-03-2018 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 Gene3D G3DSA:3.40.190.10 149 255 2.7E-13 T 29-03-2018 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 Gene3D G3DSA:3.40.190.10 390 515 1.2E-16 T 29-03-2018 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 539 723 1.1E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 Gene3D G3DSA:1.10.3720.10 516 724 2.1E-40 T 29-03-2018 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 Gene3D G3DSA:3.40.190.10 256 389 5.5E-35 T 29-03-2018 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 Gene3D G3DSA:3.40.190.10 14 148 5.0E-38 T 29-03-2018 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 SUPERFAMILY SSF161098 516 709 1.96E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 SMART SM00079 27 248 2.5E-5 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 SMART SM00062 270 491 4.8E-44 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 SMART SM00062 27 249 4.2E-56 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 SUPERFAMILY SSF53850 1 249 4.3E-64 T 29-03-2018 SPSF3K_RS08275 7290fe1e65a23362386287530a734927 724 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 514 618 5.7E-23 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 2 696 29.176 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Gene3D G3DSA:1.10.10.400 233 312 1.2E-16 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 323 9.1E-12 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 SMART SM00316 623 693 1.6E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 SMART SM00322 555 620 1.3E-9 T 29-03-2018 IPR004087 K Homology domain GO:0003676 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Pfam PF00575 S1 RNA binding domain 621 693 6.9E-19 T 29-03-2018 IPR003029 S1 domain GO:0003676 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 SUPERFAMILY SSF50249 623 705 3.0E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Gene3D G3DSA:3.30.230.70 313 556 3.3E-56 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Gene3D G3DSA:3.30.230.70 11 232 8.6E-45 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Pfam PF01138 3' exoribonuclease family, domain 1 326 459 2.7E-14 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Pfam PF01138 3' exoribonuclease family, domain 1 13 142 2.6E-17 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 SUPERFAMILY SSF54791 559 643 6.5E-20 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Pfam PF00013 KH domain 560 615 3.6E-8 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Pfam PF03725 3' exoribonuclease family, domain 2 145 208 7.3E-13 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Pfam PF03725 3' exoribonuclease family, domain 2 462 532 1.2E-7 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 SUPERFAMILY SSF46915 236 323 1.02E-13 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 SUPERFAMILY SSF54211 297 490 2.08E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 PIRSF PIRSF005499 1 725 1.7E-283 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Gene3D G3DSA:2.40.50.140 628 698 1.4E-22 T 29-03-2018 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 Gene3D G3DSA:3.30.1370.10 558 627 2.4E-12 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 694 1.0E-297 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 SUPERFAMILY SSF54211 7 142 8.6E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 SUPERFAMILY SSF55666 453 551 1.7E-28 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SPSF3K_RS02630 2a744e25cae901169a3dced59bebd9c1 748 SUPERFAMILY SSF55666 143 233 9.69E-29 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 ProSitePatterns PS01181 Ribosomal protein S21 signature. 23 35 - T 29-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 26 53 6.0E-9 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 13 66 1.8E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 Pfam PF01165 Ribosomal protein S21 15 66 7.0E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 11 67 22.381 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 Gene3D G3DSA:1.20.5.1150 26 62 3.4E-18 T 29-03-2018 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 PRINTS PR00976 Ribosomal protein S21 family signature 47 57 1.9E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 PRINTS PR00976 Ribosomal protein S21 family signature 15 23 1.9E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 PRINTS PR00976 Ribosomal protein S21 family signature 23 32 1.9E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05000 70855005ae740b75847eb98909451339 68 PRINTS PR00976 Ribosomal protein S21 family signature 35 45 1.9E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS04120 0b76b16bcf265993ffb3686084cc7eb1 340 Pfam PF11311 Protein of unknown function (DUF3114) 39 303 2.5E-99 T 29-03-2018 IPR021462 Protein of unknown function DUF3114 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 Gene3D G3DSA:2.70.150.10 43 223 5.3E-30 T 29-03-2018 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 Pfam PF00122 E1-E2 ATPase 121 303 1.7E-41 T 29-03-2018 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 Gene3D G3DSA:3.40.1110.10 336 442 3.2E-17 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 519 535 1.2E-10 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 550 575 1.2E-10 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 491 507 1.2E-10 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 SUPERFAMILY SSF56784 322 341 1.9E-50 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 SUPERFAMILY SSF56784 416 619 1.9E-50 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 72 621 1.1E-165 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 SUPERFAMILY SSF81665 223 310 5.62E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 SUPERFAMILY SSF81665 67 125 5.62E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 SUPERFAMILY SSF81665 564 602 5.62E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 94 596 1.3E-76 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 325 331 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 SUPERFAMILY SSF81653 130 222 1.27E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 519 538 1.8E-26 T 29-03-2018 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 466 476 1.8E-26 T 29-03-2018 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 172 186 1.8E-26 T 29-03-2018 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 444 455 1.8E-26 T 29-03-2018 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 554 1.8E-26 T 29-03-2018 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 323 337 1.8E-26 T 29-03-2018 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 Pfam PF00702 haloacid dehalogenase-like hydrolase 319 533 1.2E-36 T 29-03-2018 SPSF3K_RS02360 554fd77bb9578263878c81fe1503f3c9 624 Gene3D G3DSA:3.40.50.1000 443 591 1.2E-34 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 4 291 2.7E-98 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 PRINTS PR00126 ATP synthase gamma subunit signature 169 186 8.9E-36 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 PRINTS PR00126 ATP synthase gamma subunit signature 269 290 8.9E-36 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 PRINTS PR00126 ATP synthase gamma subunit signature 238 257 8.9E-36 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 PRINTS PR00126 ATP synthase gamma subunit signature 77 96 8.9E-36 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 291 32.251 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 Gene3D G3DSA:1.10.287.80 6 161 5.3E-47 T 29-03-2018 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 SUPERFAMILY SSF52943 4 291 3.01E-83 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 277 290 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 Gene3D G3DSA:1.10.287.80 162 244 7.7E-18 T 29-03-2018 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 Gene3D G3DSA:1.10.287.80 245 286 6.7E-13 T 29-03-2018 SPSF3K_RS04905 559d2ffb4f79b1806f0cce72f7eca1a5 292 Pfam PF00231 ATP synthase 4 291 3.6E-86 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS08625 afaf722e846dc239aa9b79d94c20c76e 600 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 5 592 4.9E-173 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 SPSF3K_RS08625 afaf722e846dc239aa9b79d94c20c76e 600 Pfam PF08439 Oligopeptidase F 112 181 1.1E-18 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain SPSF3K_RS08625 afaf722e846dc239aa9b79d94c20c76e 600 Gene3D G3DSA:1.10.1370.10 77 585 1.5E-43 T 29-03-2018 SPSF3K_RS08625 afaf722e846dc239aa9b79d94c20c76e 600 SUPERFAMILY SSF55486 56 595 8.71E-126 T 29-03-2018 SPSF3K_RS08625 afaf722e846dc239aa9b79d94c20c76e 600 Pfam PF01432 Peptidase family M3 202 581 5.7E-82 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 SMART SM00419 166 214 3.2E-11 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 SMART SM00100 12 132 5.3E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 SUPERFAMILY SSF46785 146 213 1.21E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 Gene3D G3DSA:2.60.120.10 1 144 1.8E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 Pfam PF13545 Crp-like helix-turn-helix domain 150 212 4.0E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 Pfam PF00027 Cyclic nucleotide-binding domain 31 115 4.1E-12 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 Gene3D G3DSA:1.10.10.10 145 215 4.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 SUPERFAMILY SSF51206 6 143 1.02E-24 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 188 203 4.7E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09420 3b41fddcc9b92cacfabc68d5bfb529de 223 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 172 188 4.7E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 Pfam PF00027 Cyclic nucleotide-binding domain 34 114 1.4E-12 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 SUPERFAMILY SSF46785 152 224 4.21E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 Gene3D G3DSA:2.60.120.10 4 149 2.3E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 SUPERFAMILY SSF51206 22 148 4.84E-27 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 191 206 4.4E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 175 191 4.4E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 SMART SM00419 169 217 3.4E-9 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 Gene3D G3DSA:1.10.10.10 150 226 1.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 Pfam PF13545 Crp-like helix-turn-helix domain 162 220 1.6E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09085 7b4e1b907eed9a9bbc04939dfd17066e 226 SMART SM00100 15 136 0.0023 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SPSF3K_RS02280 2b745c9d088abbcb1312b9dcc49bfa70 477 Pfam PF13454 FAD-NAD(P)-binding 6 154 2.9E-25 T 29-03-2018 SPSF3K_RS02280 2b745c9d088abbcb1312b9dcc49bfa70 477 Gene3D G3DSA:3.50.50.60 2 174 7.8E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS02280 2b745c9d088abbcb1312b9dcc49bfa70 477 Gene3D G3DSA:3.50.50.60 180 460 1.8E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS02280 2b745c9d088abbcb1312b9dcc49bfa70 477 SUPERFAMILY SSF51905 309 446 2.16E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS02280 2b745c9d088abbcb1312b9dcc49bfa70 477 SUPERFAMILY SSF51905 3 228 2.16E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01260 d00e23da5364a674ba5b386f67d33353 76 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 75 4.0E-30 T 29-03-2018 IPR009907 Protein of unknown function DUF1447 SPSF3K_RS01260 d00e23da5364a674ba5b386f67d33353 76 Hamap MF_01553 UPF0356 protein . 1 76 22.511 T 29-03-2018 IPR009907 Protein of unknown function DUF1447 SPSF3K_RS01260 d00e23da5364a674ba5b386f67d33353 76 Pfam PF07288 Protein of unknown function (DUF1447) 2 75 3.8E-30 T 29-03-2018 IPR009907 Protein of unknown function DUF1447 SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 Gene3D G3DSA:3.90.320.10 951 1199 2.2E-24 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 Gene3D G3DSA:3.40.50.300 620 901 1.6E-25 T 29-03-2018 SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1048 1189 7.5E-9 T 29-03-2018 SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 Pfam PF13361 UvrD-like helicase C-terminal domain 473 894 8.9E-35 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 SUPERFAMILY SSF52540 356 817 6.37E-109 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 SUPERFAMILY SSF52540 873 898 6.37E-109 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 SUPERFAMILY SSF52540 26 203 6.37E-109 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 SUPERFAMILY SSF52980 1008 1192 3.86E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 Gene3D G3DSA:3.40.50.300 476 612 1.1E-15 T 29-03-2018 SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 28 1207 9.7E-292 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 Gene3D G3DSA:3.40.50.300 18 475 7.4E-46 T 29-03-2018 SPSF3K_RS04985 95dc6b6938ee9f3f2c6d602a5962c041 1212 Pfam PF00580 UvrD/REP helicase N-terminal domain 29 463 1.4E-75 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SPSF3K_RS03060 425b1fd0bbbca2343a4e560f293ba71b 659 Gene3D G3DSA:3.90.76.10 43 208 1.0E-29 T 29-03-2018 SPSF3K_RS03060 425b1fd0bbbca2343a4e560f293ba71b 659 Gene3D G3DSA:3.40.190.10 209 311 2.4E-11 T 29-03-2018 SPSF3K_RS03060 425b1fd0bbbca2343a4e560f293ba71b 659 PIRSF PIRSF002741 2 319 5.4E-40 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SPSF3K_RS03060 425b1fd0bbbca2343a4e560f293ba71b 659 PIRSF PIRSF002741 328 600 6.5E-6 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SPSF3K_RS03060 425b1fd0bbbca2343a4e560f293ba71b 659 PIRSF PIRSF002741 605 658 110.0 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SPSF3K_RS03060 425b1fd0bbbca2343a4e560f293ba71b 659 Gene3D G3DSA:3.10.105.10 312 588 1.7E-29 T 29-03-2018 SPSF3K_RS03060 425b1fd0bbbca2343a4e560f293ba71b 659 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 521 3.2E-42 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SPSF3K_RS03060 425b1fd0bbbca2343a4e560f293ba71b 659 SUPERFAMILY SSF53850 35 596 3.8E-73 T 29-03-2018 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 159 172 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 328 354 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 Gene3D G3DSA:1.10.10.10 297 368 2.2E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 Pfam PF00140 Sigma-70 factor, region 1.2 97 129 9.8E-14 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 131 356 4.7E-38 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 SUPERFAMILY SSF88659 265 366 1.14E-28 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 Gene3D G3DSA:1.10.10.10 205 255 2.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 SUPERFAMILY SSF88946 96 205 7.59E-53 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 SUPERFAMILY SSF88659 208 282 1.87E-21 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 Pfam PF03979 Sigma-70 factor, region 1.1 13 85 3.6E-8 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 2 368 32.988 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 Gene3D G3DSA:1.10.601.10 3 204 6.3E-74 T 29-03-2018 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 Pfam PF04545 Sigma-70, region 4 303 356 3.6E-19 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 131 367 1.9E-125 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 PRINTS PR00046 Major sigma-70 factor signature 307 319 1.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 PRINTS PR00046 Major sigma-70 factor signature 159 172 1.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 PRINTS PR00046 Major sigma-70 factor signature 343 354 1.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 PRINTS PR00046 Major sigma-70 factor signature 183 191 1.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 PRINTS PR00046 Major sigma-70 factor signature 328 343 1.4E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 Pfam PF04542 Sigma-70 region 2 135 204 5.4E-23 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS05015 e748fe9b67b548d006f35fde002e52fb 369 Pfam PF04539 Sigma-70 region 3 214 290 2.4E-30 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 293 392 2.0E-8 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 55 66 3.8E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 138 151 3.8E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 111 128 3.8E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 Gene3D G3DSA:2.60.410.10 294 393 1.4E-8 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 19 269 1.2E-72 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 SUPERFAMILY SSF69189 285 404 4.12E-10 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 SUPERFAMILY SSF56601 4 293 3.22E-55 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 Gene3D G3DSA:3.40.710.10 16 293 4.2E-35 T 29-03-2018 SPSF3K_RS03055 e5837ac6f275dc8c96425103f0fdd7ac 412 SMART SM00936 293 390 1.1E-4 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SPSF3K_RS03265 c2f39c9a2ce98dab3d1f47377e5d6aad 1031 Pfam PF00271 Helicase conserved C-terminal domain 862 973 1.1E-19 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS03265 c2f39c9a2ce98dab3d1f47377e5d6aad 1031 Pfam PF08455 Bacterial SNF2 helicase associated 215 572 2.9E-55 T 29-03-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial SPSF3K_RS03265 c2f39c9a2ce98dab3d1f47377e5d6aad 1031 SUPERFAMILY SSF52540 566 781 4.9E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03265 c2f39c9a2ce98dab3d1f47377e5d6aad 1031 Gene3D G3DSA:3.40.50.10810 551 826 4.0E-49 T 29-03-2018 SPSF3K_RS03265 c2f39c9a2ce98dab3d1f47377e5d6aad 1031 SMART SM00487 581 762 7.1E-33 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS03265 c2f39c9a2ce98dab3d1f47377e5d6aad 1031 Pfam PF00176 SNF2 family N-terminal domain 599 852 1.7E-44 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 SPSF3K_RS03265 c2f39c9a2ce98dab3d1f47377e5d6aad 1031 SUPERFAMILY SSF52540 783 1029 8.4E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03265 c2f39c9a2ce98dab3d1f47377e5d6aad 1031 Gene3D G3DSA:3.40.50.300 854 1011 5.9E-38 T 29-03-2018 SPSF3K_RS03265 c2f39c9a2ce98dab3d1f47377e5d6aad 1031 SMART SM00490 891 973 8.0E-22 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 Gene3D G3DSA:3.40.50.1000 1 24 0.04 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 4.1E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 4.1E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 4.1E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.1E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 4.1E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 Gene3D G3DSA:3.40.50.1000 71 214 1.4E-31 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 7.6E-36 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 SUPERFAMILY SSF56784 1 211 2.94E-49 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 Gene3D G3DSA:1.10.150.240 25 70 1.1E-24 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SPSF3K_RS04500 09d320b6aecc628b8c93037b1fb4a4bd 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 4 184 4.8E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 Pfam PF00364 Biotin-requiring enzyme 4 76 4.9E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 SUPERFAMILY SSF55424 461 581 6.53E-40 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 Gene3D G3DSA:2.40.50.100 5 77 7.5E-15 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 SUPERFAMILY SSF51230 1 95 5.63E-27 T 29-03-2018 IPR011053 Single hybrid motif SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 129 580 9.0E-161 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 Gene3D G3DSA:1.10.287.990 166 231 4.2E-17 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 164 174 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 Gene3D G3DSA:3.50.50.60 401 473 5.9E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 315 7.4E-36 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 276 7.4E-36 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 407 429 7.4E-36 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 151 7.4E-36 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 381 397 7.4E-36 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 545 565 3.7E-64 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 270 3.7E-64 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 322 3.7E-64 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 382 396 3.7E-64 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 178 3.7E-64 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 429 3.7E-64 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 458 479 3.7E-64 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 131 153 3.7E-64 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 523 538 3.7E-64 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 Gene3D G3DSA:3.30.390.30 474 583 2.9E-39 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 462 570 1.8E-36 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 Gene3D G3DSA:3.40.50.720 109 165 0.038 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 130 442 1.1E-67 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 SUPERFAMILY SSF51905 127 180 9.72E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 SUPERFAMILY SSF51905 227 314 9.72E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 SUPERFAMILY SSF51905 343 481 9.72E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 PIRSF PIRSF000350 59 569 5.4E-80 T 29-03-2018 SPSF3K_RS07995 264391ec815267da929a3d74e5cb8da6 586 Gene3D G3DSA:3.50.50.60 240 372 2.6E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS03975 c9f30cd1962df5c7417ce7337ad72414 48 Pfam PF00471 Ribosomal protein L33 3 47 2.8E-17 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS03975 c9f30cd1962df5c7417ce7337ad72414 48 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 48 13.051 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS03975 c9f30cd1962df5c7417ce7337ad72414 48 SUPERFAMILY SSF57829 2 47 3.6E-15 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SPSF3K_RS03975 c9f30cd1962df5c7417ce7337ad72414 48 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 47 1.5E-16 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 SUPERFAMILY SSF50677 226 412 2.2E-53 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 833 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 Gene3D G3DSA:3.90.740.10 239 400 7.8E-58 T 29-03-2018 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 832 22.331 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 Pfam PF08264 Anticodon-binding domain of tRNA 684 794 1.8E-15 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 Gene3D G3DSA:3.40.50.620 1 238 2.0E-75 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 SUPERFAMILY SSF47323 653 833 5.23E-29 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 Gene3D G3DSA:3.40.50.620 401 568 2.3E-50 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 SUPERFAMILY SSF52374 413 658 2.7E-134 T 29-03-2018 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 SUPERFAMILY SSF52374 3 226 2.7E-134 T 29-03-2018 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 Pfam PF09334 tRNA synthetases class I (M) 40 165 2.4E-16 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 Gene3D G3DSA:1.10.730.10 569 832 2.0E-52 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 53 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 609 636 1.2E-6 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 401 2.4E-65 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 1.3E-54 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 1.3E-54 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 486 504 1.3E-54 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 558 568 1.3E-54 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 1.3E-54 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 525 547 1.3E-54 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SPSF3K_RS00735 07a82883073decf3362c23201e69040c 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 1.3E-54 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Pfam PF05043 Mga helix-turn-helix domain 100 163 5.2E-6 T 29-03-2018 IPR007737 Mga helix-turn-helix domain SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Pfam PF08279 HTH domain 5 61 3.0E-8 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 SUPERFAMILY SSF63520 291 394 3.53E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Pfam PF00874 PRD domain 303 390 7.1E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 SUPERFAMILY SSF55804 498 641 1.57E-25 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 SUPERFAMILY SSF63520 192 281 6.02E-7 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Gene3D G3DSA:3.40.930.10 496 642 1.9E-23 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Gene3D G3DSA:3.40.50.2300 399 488 8.5E-10 T 29-03-2018 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Gene3D G3DSA:1.10.10.10 1 69 9.9E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Gene3D G3DSA:1.10.10.10 86 155 5.0E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Gene3D G3DSA:1.10.1790.10 183 285 6.1E-7 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Gene3D G3DSA:1.10.1790.10 291 394 9.8E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 SUPERFAMILY SSF46785 3 44 3.8E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01115 eedb731978af76615262af1190c20797 642 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 501 639 2.2E-20 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 SUPERFAMILY SSF46946 136 224 5.3E-27 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 Gene3D G3DSA:3.20.190.10 5 129 4.0E-37 T 29-03-2018 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 Gene3D G3DSA:1.10.8.50 137 278 4.1E-46 T 29-03-2018 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 5 275 1.3E-104 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 Pfam PF06827 Zinc finger found in FPG and IleRS 249 276 7.0E-14 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 SUPERFAMILY SSF81624 6 140 4.19E-39 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 SUPERFAMILY SSF57716 225 276 2.42E-17 T 29-03-2018 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 5 118 1.2E-32 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 ProSitePatterns PS01242 Zinc finger FPG-type signature. 251 275 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 SMART SM01232 136 228 1.4E-37 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 136 226 6.8E-30 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 5 276 42.092 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SPSF3K_RS03950 011fd359c517811f4a2a23a27ffb3d54 278 SMART SM00898 6 120 3.7E-44 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SPSF3K_RS05815 e61fc7c0f24c07720dd3a7778d6fe264 245 SUPERFAMILY SSF53335 1 238 1.64E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS05815 e61fc7c0f24c07720dd3a7778d6fe264 245 SMART SM00650 17 179 9.3E-58 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SPSF3K_RS05815 e61fc7c0f24c07720dd3a7778d6fe264 245 Gene3D G3DSA:1.10.8.100 184 242 3.8E-31 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 SPSF3K_RS05815 e61fc7c0f24c07720dd3a7778d6fe264 245 Gene3D G3DSA:3.40.50.150 1 183 4.2E-35 T 29-03-2018 SPSF3K_RS05815 e61fc7c0f24c07720dd3a7778d6fe264 245 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 60 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SPSF3K_RS05815 e61fc7c0f24c07720dd3a7778d6fe264 245 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 239 1.2E-74 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SPSF3K_RS04460 b56afe76343935fa4ea6ca019eae07eb 433 SMART SM00471 49 181 2.3E-11 T 29-03-2018 IPR003607 HD/PDEase domain SPSF3K_RS04460 b56afe76343935fa4ea6ca019eae07eb 433 Gene3D G3DSA:1.10.3210.10 2 307 9.2E-73 T 29-03-2018 SPSF3K_RS04460 b56afe76343935fa4ea6ca019eae07eb 433 Pfam PF01966 HD domain 53 173 1.0E-11 T 29-03-2018 IPR006674 HD domain SPSF3K_RS04460 b56afe76343935fa4ea6ca019eae07eb 433 SUPERFAMILY SSF109604 2 419 8.33E-119 T 29-03-2018 SPSF3K_RS01685 b5c881c09d119b3ccd3b73a82b41ee14 479 SMART SM00640 37 446 1.8E-116 T 29-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 SPSF3K_RS01685 b5c881c09d119b3ccd3b73a82b41ee14 479 SUPERFAMILY SSF75005 27 341 5.14E-85 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SPSF3K_RS01685 b5c881c09d119b3ccd3b73a82b41ee14 479 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 37 340 9.3E-88 T 29-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal SPSF3K_RS01685 b5c881c09d119b3ccd3b73a82b41ee14 479 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 352 467 1.6E-17 T 29-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal SPSF3K_RS01685 b5c881c09d119b3ccd3b73a82b41ee14 479 Gene3D G3DSA:2.60.120.560 351 472 9.8E-23 T 29-03-2018 SPSF3K_RS01685 b5c881c09d119b3ccd3b73a82b41ee14 479 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 20 456 4.3E-162 T 29-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 SPSF3K_RS01685 b5c881c09d119b3ccd3b73a82b41ee14 479 SUPERFAMILY SSF49899 340 477 3.72E-24 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SPSF3K_RS01685 b5c881c09d119b3ccd3b73a82b41ee14 479 Gene3D G3DSA:2.115.10.20 2 350 2.4E-72 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 81 90 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 SUPERFAMILY SSF53187 384 466 1.26E-64 T 29-03-2018 SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 SUPERFAMILY SSF53187 2 187 1.26E-64 T 29-03-2018 SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 Gene3D G3DSA:3.30.70.360 204 284 1.1E-12 T 29-03-2018 SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 Pfam PF01546 Peptidase family M20/M25/M40 85 463 8.0E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 SUPERFAMILY SSF55031 187 381 9.72E-51 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 TIGRFAM TIGR01886 dipeptidase: dipeptidase PepV 2 467 4.0E-218 T 29-03-2018 IPR011291 Peptidase M20A, peptidase V SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 Gene3D G3DSA:3.30.70.360 285 372 7.7E-25 T 29-03-2018 SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 13 462 2.7E-173 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 Gene3D G3DSA:3.40.630.10 4 193 9.4E-26 T 29-03-2018 SPSF3K_RS07790 66f700eedf3a1413c3390d49e9d3428f 467 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 115 154 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPSF3K_RS00685 c7665a58ef6c35baadedda0e808e3376 496 Gene3D G3DSA:3.60.60.10 26 262 1.2E-50 T 29-03-2018 SPSF3K_RS00685 c7665a58ef6c35baadedda0e808e3376 496 Pfam PF03577 Peptidase family C69 25 418 2.2E-85 T 29-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 SPSF3K_RS07780 ac647f9ae46ba671a76c51239566e674 226 Gene3D G3DSA:3.40.50.1360 1 138 1.4E-37 T 29-03-2018 SPSF3K_RS07780 ac647f9ae46ba671a76c51239566e674 226 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 5 219 4.9E-82 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SPSF3K_RS07780 ac647f9ae46ba671a76c51239566e674 226 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 221 32.379 T 29-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SPSF3K_RS07780 ac647f9ae46ba671a76c51239566e674 226 SUPERFAMILY SSF100950 2 141 1.42E-41 T 29-03-2018 SPSF3K_RS07780 ac647f9ae46ba671a76c51239566e674 226 Gene3D G3DSA:3.30.70.260 139 201 4.9E-21 T 29-03-2018 SPSF3K_RS07780 ac647f9ae46ba671a76c51239566e674 226 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 50 217 1.3E-58 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SPSF3K_RS07780 ac647f9ae46ba671a76c51239566e674 226 SUPERFAMILY SSF75445 127 203 4.84E-20 T 29-03-2018 SPSF3K_RS05195 3712b43eb4dceacc9b4e82ea94cbf5b3 302 SUPERFAMILY SSF53850 98 292 1.99E-10 T 29-03-2018 SPSF3K_RS05195 3712b43eb4dceacc9b4e82ea94cbf5b3 302 Pfam PF03466 LysR substrate binding domain 99 293 4.0E-7 T 29-03-2018 IPR005119 LysR, substrate-binding SPSF3K_RS05195 3712b43eb4dceacc9b4e82ea94cbf5b3 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.4E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS05195 3712b43eb4dceacc9b4e82ea94cbf5b3 302 Gene3D G3DSA:1.10.10.10 1 92 1.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05195 3712b43eb4dceacc9b4e82ea94cbf5b3 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS05195 3712b43eb4dceacc9b4e82ea94cbf5b3 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS05195 3712b43eb4dceacc9b4e82ea94cbf5b3 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS05195 3712b43eb4dceacc9b4e82ea94cbf5b3 302 SUPERFAMILY SSF46785 1 84 3.27E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05195 3712b43eb4dceacc9b4e82ea94cbf5b3 302 Gene3D G3DSA:3.40.190.10 93 209 7.5E-9 T 29-03-2018 SPSF3K_RS01645 90f96ec6b6711a482e237c7f624b492b 314 SUPERFAMILY SSF144083 247 312 2.75E-12 T 29-03-2018 SPSF3K_RS01645 90f96ec6b6711a482e237c7f624b492b 314 SUPERFAMILY SSF143865 19 246 9.81E-45 T 29-03-2018 SPSF3K_RS01645 90f96ec6b6711a482e237c7f624b492b 314 Gene3D G3DSA:3.30.460.20 5 131 1.5E-17 T 29-03-2018 SPSF3K_RS01645 90f96ec6b6711a482e237c7f624b492b 314 Pfam PF01544 CorA-like Mg2+ transporter protein 22 311 2.7E-64 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SPSF3K_RS01645 90f96ec6b6711a482e237c7f624b492b 314 Gene3D G3DSA:1.20.58.340 245 314 1.2E-11 T 29-03-2018 SPSF3K_RS01645 90f96ec6b6711a482e237c7f624b492b 314 Gene3D G3DSA:1.20.58.340 132 244 9.8E-11 T 29-03-2018 SPSF3K_RS00005 b3da90c6d527120079f53649e49aeead 257 SUPERFAMILY SSF109709 89 197 6.54E-34 T 29-03-2018 SPSF3K_RS00005 b3da90c6d527120079f53649e49aeead 257 Pfam PF02195 ParB-like nuclease domain 7 95 1.3E-23 T 29-03-2018 IPR003115 ParB/Sulfiredoxin SPSF3K_RS00005 b3da90c6d527120079f53649e49aeead 257 SMART SM00470 6 96 3.3E-31 T 29-03-2018 IPR003115 ParB/Sulfiredoxin SPSF3K_RS00005 b3da90c6d527120079f53649e49aeead 257 SUPERFAMILY SSF110849 6 98 8.89E-27 T 29-03-2018 IPR003115 ParB/Sulfiredoxin SPSF3K_RS00005 b3da90c6d527120079f53649e49aeead 257 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 3 182 1.8E-56 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 SPSF3K_RS00005 b3da90c6d527120079f53649e49aeead 257 Gene3D G3DSA:1.10.10.730 97 144 8.7E-17 T 29-03-2018 SPSF3K_RS00005 b3da90c6d527120079f53649e49aeead 257 Gene3D G3DSA:3.90.1530.10 1 96 3.8E-33 T 29-03-2018 SPSF3K_RS07415 341a60e0ab3e584b57b4d232f8649f5e 171 SMART SM00507 71 128 6.7E-4 T 29-03-2018 IPR003615 HNH nuclease SPSF3K_RS07415 341a60e0ab3e584b57b4d232f8649f5e 171 Pfam PF01844 HNH endonuclease 84 129 1.5E-5 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SPSF3K_RS07415 341a60e0ab3e584b57b4d232f8649f5e 171 Gene3D G3DSA:3.40.1800.10 62 145 2.9E-12 T 29-03-2018 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 SMART SM00382 444 611 1.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 SMART SM00382 113 260 4.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 610 681 1.3E-19 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 Gene3D G3DSA:3.40.50.300 28 270 5.7E-29 T 29-03-2018 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 SMART SM01086 610 697 1.6E-24 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 SUPERFAMILY SSF52540 393 678 8.3E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 Gene3D G3DSA:1.10.8.60 271 394 1.1E-28 T 29-03-2018 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 Gene3D G3DSA:1.10.8.60 625 702 2.5E-19 T 29-03-2018 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 Gene3D G3DSA:3.40.50.300 395 624 6.3E-48 T 29-03-2018 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 118 250 7.5E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 SUPERFAMILY SSF52540 76 330 5.87E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 Pfam PF07724 AAA domain (Cdc48 subfamily) 443 602 4.2E-42 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 478 496 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 493 511 3.6E-28 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 523 541 3.6E-28 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 448 466 3.6E-28 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS05465 92e8f9397bec6da72a1f76a642db9e9d 702 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 556 570 3.6E-28 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SUPERFAMILY SSF52540 790 996 2.25E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 Pfam PF02559 CarD-like/TRCF domain 488 583 3.6E-28 T 29-03-2018 IPR003711 CarD-like/TRCF domain SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 Pfam PF00271 Helicase conserved C-terminal domain 814 917 4.1E-14 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SUPERFAMILY SSF143517 1000 1156 9.55E-32 T 29-03-2018 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SMART SM00982 1012 1112 4.1E-34 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SUPERFAMILY SSF52540 368 477 6.81E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SUPERFAMILY SSF52540 21 359 2.12E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SMART SM01058 487 584 1.9E-43 T 29-03-2018 IPR003711 CarD-like/TRCF domain SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 Gene3D G3DSA:3.30.2060.10 140 216 1.0E-5 T 29-03-2018 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 Gene3D G3DSA:3.40.50.300 798 964 2.4E-21 T 29-03-2018 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 Gene3D G3DSA:3.40.50.300 519 782 7.1E-39 T 29-03-2018 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 Pfam PF00270 DEAD/DEAH box helicase 633 772 5.0E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SMART SM00487 608 798 2.0E-34 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SUPERFAMILY SSF52540 533 791 2.33E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 Pfam PF03461 TRCF domain 1013 1100 5.5E-24 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 Pfam PF14814 Bifunctional transglycosylase second domain 142 183 8.7E-7 T 29-03-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SMART SM00490 834 918 1.6E-15 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 SUPERFAMILY SSF141259 478 556 4.84E-23 T 29-03-2018 IPR003711 CarD-like/TRCF domain SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 156 1079 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SPSF3K_RS10885 70bf8c7eabf31cf94eb4e15f78705160 1167 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 35 1119 28.358 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SPSF3K_RS08220 289a7553696d828878ec1aa34f8e5eb1 339 SUPERFAMILY SSF47413 1 58 8.44E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS08220 289a7553696d828878ec1aa34f8e5eb1 339 Gene3D G3DSA:3.40.50.2300 174 337 7.6E-27 T 29-03-2018 SPSF3K_RS08220 289a7553696d828878ec1aa34f8e5eb1 339 Gene3D G3DSA:3.40.50.2300 56 173 5.9E-21 T 29-03-2018 SPSF3K_RS08220 289a7553696d828878ec1aa34f8e5eb1 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.9E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS08220 289a7553696d828878ec1aa34f8e5eb1 339 SMART SM00354 1 71 6.4E-28 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS08220 289a7553696d828878ec1aa34f8e5eb1 339 SUPERFAMILY SSF53822 60 334 6.87E-46 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS08220 289a7553696d828878ec1aa34f8e5eb1 339 Pfam PF13377 Periplasmic binding protein-like domain 175 334 5.4E-23 T 29-03-2018 SPSF3K_RS08220 289a7553696d828878ec1aa34f8e5eb1 339 Gene3D G3DSA:1.10.260.40 1 55 9.4E-20 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 430 444 1.1E-26 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 279 293 1.1E-26 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 651 1.1E-26 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 563 573 1.1E-26 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 616 635 1.1E-26 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 Pfam PF00403 Heavy-metal-associated domain 5 65 2.0E-14 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 Gene3D G3DSA:3.40.50.1000 576 670 1.5E-21 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 SUPERFAMILY SSF81665 195 233 1.7E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 SUPERFAMILY SSF81665 330 424 1.7E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 SUPERFAMILY SSF81665 665 712 1.7E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 Gene3D G3DSA:3.30.70.100 2 88 8.6E-18 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 Gene3D G3DSA:1.20.1110.10 195 450 1.1E-50 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 SUPERFAMILY SSF56784 486 723 1.44E-59 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 SUPERFAMILY SSF56784 428 448 1.44E-59 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 197 725 1.3E-128 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 161 725 1.2E-197 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 432 438 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 ProSitePatterns PS01229 Hypothetical cof family signature 2. 616 638 - T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 201 696 7.1E-98 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 SUPERFAMILY SSF81653 234 329 1.2E-28 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00943 Copper-transporting ATPase signature 593 610 2.4E-11 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00943 Copper-transporting ATPase signature 126 144 2.4E-11 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00943 Copper-transporting ATPase signature 352 366 2.4E-11 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00943 Copper-transporting ATPase signature 146 165 2.4E-11 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00943 Copper-transporting ATPase signature 199 218 2.4E-11 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 PRINTS PR00943 Copper-transporting ATPase signature 413 428 2.4E-11 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 Pfam PF00122 E1-E2 ATPase 231 409 3.8E-59 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 Pfam PF00702 haloacid dehalogenase-like hydrolase 427 630 1.8E-43 T 29-03-2018 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 Gene3D G3DSA:3.40.1110.10 451 575 3.0E-37 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 SUPERFAMILY SSF55008 2 73 7.07E-18 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS09925 b64bc4423e9c3e427d6ab269164c8c65 733 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 143 726 6.4E-187 T 29-03-2018 SPSF3K_RS04290 aa88aff9e83b61e578764986771ff2f4 429 Gene3D G3DSA:3.20.20.70 5 174 2.2E-7 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS04290 aa88aff9e83b61e578764986771ff2f4 429 Pfam PF16325 Peptidase family U32 C-terminal domain 327 408 1.1E-20 T 29-03-2018 IPR032525 Peptidase family U32, C-terminal SPSF3K_RS04290 aa88aff9e83b61e578764986771ff2f4 429 ProSitePatterns PS01276 Peptidase family U32 signature. 166 184 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 SPSF3K_RS04290 aa88aff9e83b61e578764986771ff2f4 429 Pfam PF01136 Peptidase family U32 85 312 3.5E-87 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 SPSF3K_RS06910 f2a34e222045fe6d229007bb7dfa152e 216 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 15 215 3.1E-58 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 SPSF3K_RS06910 f2a34e222045fe6d229007bb7dfa152e 216 Pfam PF03006 Haemolysin-III related 14 208 4.4E-29 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 SPSF3K_RS01830 1efc1f2b9c91272761fbe853f62ffb85 1103 Gene3D G3DSA:2.60.40.1710 433 563 9.8E-20 T 29-03-2018 SPSF3K_RS01830 1efc1f2b9c91272761fbe853f62ffb85 1103 Gene3D G3DSA:2.60.40.10 727 816 5.1E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold SPSF3K_RS01830 1efc1f2b9c91272761fbe853f62ffb85 1103 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 343 353 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site SPSF3K_RS01830 1efc1f2b9c91272761fbe853f62ffb85 1103 SUPERFAMILY SSF52743 2 148 4.58E-45 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPSF3K_RS01830 1efc1f2b9c91272761fbe853f62ffb85 1103 SUPERFAMILY SSF52743 305 427 4.58E-45 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPSF3K_RS01830 1efc1f2b9c91272761fbe853f62ffb85 1103 Pfam PF06280 Fn3-like domain 440 554 3.4E-16 T 29-03-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 SPSF3K_RS01830 1efc1f2b9c91272761fbe853f62ffb85 1103 Pfam PF00082 Subtilase family 1 417 2.4E-36 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPSF3K_RS01830 1efc1f2b9c91272761fbe853f62ffb85 1103 Gene3D G3DSA:3.40.50.200 1 432 1.8E-51 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPSF3K_RS04875 5d853f38b029c68d85e2cd83d8d87172 798 SUPERFAMILY SSF53756 3 797 3.37E-275 T 29-03-2018 SPSF3K_RS04875 5d853f38b029c68d85e2cd83d8d87172 798 Pfam PF00343 Carbohydrate phosphorylase 94 796 3.1E-288 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SPSF3K_RS04875 5d853f38b029c68d85e2cd83d8d87172 798 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 5 796 0.0 T 29-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SPSF3K_RS04875 5d853f38b029c68d85e2cd83d8d87172 798 Gene3D G3DSA:3.40.50.2000 462 781 6.7E-119 T 29-03-2018 SPSF3K_RS04875 5d853f38b029c68d85e2cd83d8d87172 798 Gene3D G3DSA:3.40.50.2000 5 461 1.3E-156 T 29-03-2018 SPSF3K_RS04875 5d853f38b029c68d85e2cd83d8d87172 798 PIRSF PIRSF000460 3 798 1.5E-206 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SPSF3K_RS08255 7ccd61534c941c4970f9e0cc89b00b51 419 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 12 409 1.8E-161 T 29-03-2018 IPR024024 D-alanyl transfer protein DltB SPSF3K_RS08255 7ccd61534c941c4970f9e0cc89b00b51 419 PIRSF PIRSF500216 10 414 3.3E-167 T 29-03-2018 IPR024024 D-alanyl transfer protein DltB SPSF3K_RS08255 7ccd61534c941c4970f9e0cc89b00b51 419 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 56 394 6.4E-15 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT SPSF3K_RS08255 7ccd61534c941c4970f9e0cc89b00b51 419 PIRSF PIRSF016636 13 409 3.9E-75 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 Pfam PF00633 Helix-hairpin-helix motif 113 141 6.4E-6 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 Gene3D G3DSA:1.10.340.30 34 131 5.1E-33 T 29-03-2018 SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 Pfam PF14815 NUDIX domain 248 375 5.3E-17 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 Gene3D G3DSA:3.90.79.10 243 379 8.4E-13 T 29-03-2018 SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 48 176 6.7E-19 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 SUPERFAMILY SSF55811 233 378 1.08E-20 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 SUPERFAMILY SSF48150 16 235 8.95E-71 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 20 281 7.1E-98 T 29-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 SMART SM00478 52 203 9.6E-44 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 SPSF3K_RS01620 3d9b63b16cd0ffff09d86bf8817aea13 379 Gene3D G3DSA:1.10.1670.10 132 238 1.3E-29 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 147 172 3.3E-89 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 3.3E-89 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 3.3E-89 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 68 88 3.3E-89 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 19 37 3.3E-89 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 173 196 3.3E-89 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 3.3E-89 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 3.3E-89 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 110 133 3.3E-89 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 SUPERFAMILY SSF103491 5 421 1.44E-115 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 Hamap MF_01465 Protein translocase subunit SecY [secY]. 6 430 26.618 T 29-03-2018 IPR026593 Protein translocase subunit SecY SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 Pfam PF00344 SecY translocase 69 412 7.7E-97 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 Gene3D G3DSA:1.10.3370.10 1 434 1.6E-133 T 29-03-2018 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 16 426 8.9E-133 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 PIRSF PIRSF004557 1 433 1.2E-115 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SPSF3K_RS10420 f068aced777565e3fd91a3dd12cfab1b 434 ProSitePatterns PS00755 Protein secY signature 1. 69 88 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 Gene3D G3DSA:2.40.30.10 304 396 1.2E-29 T 29-03-2018 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.8E-13 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 3.3E-221 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 398 59.289 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 Gene3D G3DSA:3.40.50.300 1 77 1.6E-10 T 29-03-2018 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 Gene3D G3DSA:2.40.30.10 195 302 3.4E-30 T 29-03-2018 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 Pfam PF03143 Elongation factor Tu C-terminal domain 302 396 1.3E-31 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 SUPERFAMILY SSF52540 6 222 1.59E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 PRINTS PR00315 GTP-binding elongation factor signature 61 69 2.0E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 PRINTS PR00315 GTP-binding elongation factor signature 81 91 2.0E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.0E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 PRINTS PR00315 GTP-binding elongation factor signature 97 108 2.0E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 PRINTS PR00315 GTP-binding elongation factor signature 134 143 2.0E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 Gene3D G3DSA:3.40.50.300 78 194 4.3E-33 T 29-03-2018 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 1.0E-58 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 SUPERFAMILY SSF50447 206 305 2.55E-29 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 SUPERFAMILY SSF50465 306 397 1.27E-35 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SPSF3K_RS04435 50c8e33a8300c17e9c81c0ae872e4566 398 Pfam PF03144 Elongation factor Tu domain 2 228 297 2.1E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SPSF3K_RS09035 eb43eb48f4182f62719796743c1eb6ef 345 Pfam PF13180 PDZ domain 131 195 1.1E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SPSF3K_RS09035 eb43eb48f4182f62719796743c1eb6ef 345 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 231 338 5.9E-6 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 SPSF3K_RS09035 eb43eb48f4182f62719796743c1eb6ef 345 Gene3D G3DSA:3.30.230.10 33 345 3.3E-33 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS09035 eb43eb48f4182f62719796743c1eb6ef 345 SUPERFAMILY SSF54211 164 343 4.55E-23 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS08955 e591b08719934c08dac417d47aabe5c8 323 Gene3D G3DSA:3.30.420.40 1 123 6.0E-28 T 29-03-2018 SPSF3K_RS08955 e591b08719934c08dac417d47aabe5c8 323 SUPERFAMILY SSF53067 4 318 1.81E-69 T 29-03-2018 SPSF3K_RS08955 e591b08719934c08dac417d47aabe5c8 323 Pfam PF00480 ROK family 6 319 1.9E-72 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SPSF3K_RS08955 e591b08719934c08dac417d47aabe5c8 323 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 319 3.9E-100 T 29-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SPSF3K_RS08955 e591b08719934c08dac417d47aabe5c8 323 Gene3D G3DSA:3.30.420.40 124 321 6.3E-60 T 29-03-2018 SPSF3K_RS08955 e591b08719934c08dac417d47aabe5c8 323 ProSitePatterns PS01125 ROK family signature. 139 166 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SPSF3K_RS07760 42080816c68b18eb69c1463862779646 237 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 29-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07760 42080816c68b18eb69c1463862779646 237 Gene3D G3DSA:3.40.50.1580 8 236 7.9E-57 T 29-03-2018 SPSF3K_RS07760 42080816c68b18eb69c1463862779646 237 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 1.2E-87 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 SPSF3K_RS07760 42080816c68b18eb69c1463862779646 237 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 235 42.93 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 SPSF3K_RS07760 42080816c68b18eb69c1463862779646 237 SUPERFAMILY SSF53167 2 234 9.16E-86 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPSF3K_RS07760 42080816c68b18eb69c1463862779646 237 Pfam PF01048 Phosphorylase superfamily 16 218 8.9E-45 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPSF3K_RS01130 ece6b1ac8b2308b5e1eecc5fe04e64cc 290 SUPERFAMILY SSF53335 16 288 1.89E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS01130 ece6b1ac8b2308b5e1eecc5fe04e64cc 290 SMART SM00650 34 210 2.1E-86 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SPSF3K_RS01130 ece6b1ac8b2308b5e1eecc5fe04e64cc 290 Pfam PF00398 Ribosomal RNA adenine dimethylase 18 254 4.2E-66 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SPSF3K_RS01130 ece6b1ac8b2308b5e1eecc5fe04e64cc 290 Gene3D G3DSA:3.40.50.150 5 223 8.1E-60 T 29-03-2018 SPSF3K_RS01130 ece6b1ac8b2308b5e1eecc5fe04e64cc 290 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 18 286 55.99 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SPSF3K_RS01130 ece6b1ac8b2308b5e1eecc5fe04e64cc 290 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 18 284 1.4E-82 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SPSF3K_RS01130 ece6b1ac8b2308b5e1eecc5fe04e64cc 290 Gene3D G3DSA:1.10.8.100 224 287 1.2E-21 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 SPSF3K_RS01130 ece6b1ac8b2308b5e1eecc5fe04e64cc 290 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 50 77 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SPSF3K_RS09455 f45e1eb51dbbe3567e8abee4b49e22ec 240 Pfam PF00005 ABC transporter 20 161 8.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS09455 f45e1eb51dbbe3567e8abee4b49e22ec 240 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS09455 f45e1eb51dbbe3567e8abee4b49e22ec 240 SUPERFAMILY SSF52540 5 224 1.63E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09455 f45e1eb51dbbe3567e8abee4b49e22ec 240 SMART SM00382 29 208 3.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS09455 f45e1eb51dbbe3567e8abee4b49e22ec 240 Gene3D G3DSA:3.40.50.300 1 239 2.1E-59 T 29-03-2018 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 Gene3D G3DSA:3.90.930.12 2 82 7.0E-28 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 Pfam PF00347 Ribosomal protein L6 12 82 1.7E-18 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 Pfam PF00347 Ribosomal protein L6 91 164 8.1E-18 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 Gene3D G3DSA:3.90.930.12 83 178 1.7E-36 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.115 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 7.8E-28 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 7.8E-28 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 7.8E-28 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 SUPERFAMILY SSF56053 1 82 3.01E-26 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 PIRSF PIRSF002162 1 177 2.8E-47 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.4E-71 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPSF3K_RS10445 8d43c1d36469813a655b280d47983109 178 SUPERFAMILY SSF56053 83 177 5.76E-34 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 SMART SM01086 654 742 1.6E-25 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 Gene3D G3DSA:1.10.8.60 654 759 2.9E-21 T 29-03-2018 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 Pfam PF02151 UvrB/uvrC motif 371 404 5.3E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 Pfam PF07724 AAA domain (Cdc48 subfamily) 483 646 4.3E-49 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 251 263 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 SUPERFAMILY SSF52540 433 731 7.24E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 SUPERFAMILY SSF52540 117 369 4.32E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 Gene3D G3DSA:3.40.50.300 115 298 3.1E-25 T 29-03-2018 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 SMART SM00382 484 655 3.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 SMART SM00382 155 295 1.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 518 536 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 160 280 1.4E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 Gene3D G3DSA:3.40.50.300 439 653 2.2E-42 T 29-03-2018 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 654 728 1.0E-21 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 488 506 1.7E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 533 551 1.7E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 562 580 1.7E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 595 609 1.7E-37 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS08870 1a57aa032b6d6408d8301e64e63a7df6 761 Gene3D G3DSA:1.10.8.60 299 434 4.3E-35 T 29-03-2018 SPSF3K_RS00950 f702344a4206a5c42a987e933d0130a9 419 Gene3D G3DSA:1.20.120.520 186 257 0.0014 T 29-03-2018 SPSF3K_RS00950 f702344a4206a5c42a987e933d0130a9 419 SUPERFAMILY SSF52218 1 174 4.39E-39 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS00950 f702344a4206a5c42a987e933d0130a9 419 Pfam PF13596 PAS domain 243 356 4.9E-30 T 29-03-2018 SPSF3K_RS00950 f702344a4206a5c42a987e933d0130a9 419 Pfam PF03358 NADPH-dependent FMN reductase 1 148 2.7E-32 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SPSF3K_RS00950 f702344a4206a5c42a987e933d0130a9 419 Gene3D G3DSA:3.40.50.360 1 185 1.7E-27 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS04305 a97decea2e493f7656d7e216d534c361 549 Gene3D G3DSA:3.40.190.10 206 302 6.5E-16 T 29-03-2018 SPSF3K_RS04305 a97decea2e493f7656d7e216d534c361 549 Gene3D G3DSA:3.10.105.10 303 517 5.7E-43 T 29-03-2018 SPSF3K_RS04305 a97decea2e493f7656d7e216d534c361 549 PIRSF PIRSF002741 1 549 4.3E-82 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SPSF3K_RS04305 a97decea2e493f7656d7e216d534c361 549 Gene3D G3DSA:3.90.76.10 45 205 5.7E-36 T 29-03-2018 SPSF3K_RS04305 a97decea2e493f7656d7e216d534c361 549 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 468 2.5E-72 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SPSF3K_RS04305 a97decea2e493f7656d7e216d534c361 549 SUPERFAMILY SSF53850 31 538 1.21E-110 T 29-03-2018 SPSF3K_RS05050 87b90fab478ea2f9c3af60956c693449 591 Pfam PF00534 Glycosyl transferases group 1 197 339 4.9E-21 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SPSF3K_RS05050 87b90fab478ea2f9c3af60956c693449 591 Gene3D G3DSA:3.40.50.2000 183 358 3.1E-23 T 29-03-2018 SPSF3K_RS05050 87b90fab478ea2f9c3af60956c693449 591 Gene3D G3DSA:3.40.50.2000 1 182 2.2E-5 T 29-03-2018 SPSF3K_RS05050 87b90fab478ea2f9c3af60956c693449 591 SUPERFAMILY SSF53756 3 371 6.6E-42 T 29-03-2018 SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 Gene3D G3DSA:3.40.50.720 47 244 4.6E-68 T 29-03-2018 SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 Gene3D G3DSA:3.40.50.720 1 46 7.1E-10 T 29-03-2018 SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.1E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 6.1E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.1E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.1E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.1E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.1E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 5.5E-68 T 29-03-2018 SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.4E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.4E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.4E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 SUPERFAMILY SSF51735 4 243 2.06E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 189 2.8E-8 T 29-03-2018 SPSF3K_RS10090 34f101294cf6b9dd52af88079061bc1b 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 241 4.3E-99 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SPSF3K_RS05310 15d0fa15d57430a344149b5d4cd8accf 307 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 1.4E-40 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SPSF3K_RS05310 15d0fa15d57430a344149b5d4cd8accf 307 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 177 301 1.1E-36 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SPSF3K_RS05310 15d0fa15d57430a344149b5d4cd8accf 307 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 301 8.1E-92 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 SPSF3K_RS05310 15d0fa15d57430a344149b5d4cd8accf 307 Gene3D G3DSA:3.40.50.720 1 174 1.2E-21 T 29-03-2018 SPSF3K_RS05310 15d0fa15d57430a344149b5d4cd8accf 307 SUPERFAMILY SSF51735 1 133 5.57E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS05310 15d0fa15d57430a344149b5d4cd8accf 307 Gene3D G3DSA:1.10.1040.10 176 307 1.1E-33 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPSF3K_RS05310 15d0fa15d57430a344149b5d4cd8accf 307 SUPERFAMILY SSF48179 176 301 4.42E-32 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPSF3K_RS10010 e1eef2f3c4584b7126f5b7882dce63af 149 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 4 132 7.2E-36 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SPSF3K_RS10010 e1eef2f3c4584b7126f5b7882dce63af 149 Gene3D G3DSA:3.40.50.300 1 146 1.9E-44 T 29-03-2018 SPSF3K_RS10010 e1eef2f3c4584b7126f5b7882dce63af 149 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 5 123 6.5E-33 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SPSF3K_RS10010 e1eef2f3c4584b7126f5b7882dce63af 149 SUPERFAMILY SSF52540 18 106 1.49E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 58 85 7.0E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 8 25 7.0E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 7.0E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 7.0E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 7.0E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 7.0E-42 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 Gene3D G3DSA:3.40.50.720 1 182 4.9E-38 T 29-03-2018 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 4 325 36.126 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 321 1.5E-51 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 SUPERFAMILY SSF51735 5 181 4.73E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 Gene3D G3DSA:1.10.1040.10 183 333 1.8E-52 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 SUPERFAMILY SSF48179 182 334 3.4E-53 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 PIRSF PIRSF000114 1 335 1.0E-105 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS00930 b0d4b4dacd30c74804339da8e1304dc3 338 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 162 3.3E-51 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 SUPERFAMILY SSF56037 217 400 1.86E-67 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 SUPERFAMILY SSF55681 472 694 1.59E-50 T 29-03-2018 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Gene3D G3DSA:3.30.930.10 494 695 5.3E-36 T 29-03-2018 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Gene3D G3DSA:3.30.70.380 704 801 5.4E-27 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Pfam PF03147 Ferredoxin-fold anticodon binding domain 708 801 4.3E-30 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Gene3D G3DSA:3.30.56.10 408 480 2.6E-19 T 29-03-2018 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Pfam PF01588 Putative tRNA binding domain 45 144 6.5E-19 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Pfam PF03483 B3/4 domain 221 390 8.6E-65 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 SUPERFAMILY SSF54991 703 801 2.09E-31 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 SMART SM00874 408 476 1.3E-22 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Gene3D G3DSA:3.30.56.10 2 195 1.5E-47 T 29-03-2018 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 795 45.625 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 SMART SM00896 708 801 5.5E-41 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Pfam PF03484 tRNA synthetase B5 domain 411 476 4.8E-15 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 801 1.0E-255 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 SMART SM00873 218 391 3.0E-84 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 SUPERFAMILY SSF50249 36 197 1.8E-43 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 SUPERFAMILY SSF46955 408 480 1.92E-17 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS04950 35d93b0f5f26f00ce2aa7919a32fed9d 801 Gene3D G3DSA:3.50.40.10 202 402 1.1E-65 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SPSF3K_RS05165 a1b0f7e416f42d146d92b2508bdf4ca6 380 PIRSF PIRSF005572 1 380 2.9E-114 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SPSF3K_RS05165 a1b0f7e416f42d146d92b2508bdf4ca6 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SPSF3K_RS05165 a1b0f7e416f42d146d92b2508bdf4ca6 380 Gene3D G3DSA:3.90.1150.10 264 380 3.7E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS05165 a1b0f7e416f42d146d92b2508bdf4ca6 380 SUPERFAMILY SSF53383 1 374 2.67E-92 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS05165 a1b0f7e416f42d146d92b2508bdf4ca6 380 Gene3D G3DSA:3.40.640.10 11 256 9.4E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS05165 a1b0f7e416f42d146d92b2508bdf4ca6 380 Pfam PF00266 Aminotransferase class-V 2 365 5.8E-66 T 29-03-2018 IPR000192 Aminotransferase class V domain SPSF3K_RS06280 102cb14df600511ce344187d71a3483d 297 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 127 141 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS06280 102cb14df600511ce344187d71a3483d 297 Gene3D G3DSA:3.30.2350.10 75 297 1.4E-62 T 29-03-2018 SPSF3K_RS06280 102cb14df600511ce344187d71a3483d 297 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 32 291 6.4E-67 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS06280 102cb14df600511ce344187d71a3483d 297 SUPERFAMILY SSF55120 69 290 1.26E-65 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS06280 102cb14df600511ce344187d71a3483d 297 Pfam PF00849 RNA pseudouridylate synthase 84 237 1.9E-30 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS02180 d4518c904db986510327a7d4d912ddee 211 Gene3D G3DSA:1.10.10.60 20 59 2.5E-14 T 29-03-2018 SPSF3K_RS02180 d4518c904db986510327a7d4d912ddee 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 3.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS02180 d4518c904db986510327a7d4d912ddee 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 3.6E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS02180 d4518c904db986510327a7d4d912ddee 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 38 69 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site SPSF3K_RS02180 d4518c904db986510327a7d4d912ddee 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 72 1.7E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS02180 d4518c904db986510327a7d4d912ddee 211 SUPERFAMILY SSF46689 24 96 1.08E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS02180 d4518c904db986510327a7d4d912ddee 211 Gene3D G3DSA:1.10.10.60 60 163 1.8E-8 T 29-03-2018 SPSF3K_RS03505 63f6d477b144513bdf1b39ae3a8df89c 386 Gene3D G3DSA:1.10.443.10 183 385 9.0E-34 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS03505 63f6d477b144513bdf1b39ae3a8df89c 386 Pfam PF00589 Phage integrase family 181 369 4.6E-25 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS03505 63f6d477b144513bdf1b39ae3a8df89c 386 SUPERFAMILY SSF56349 69 375 1.47E-58 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPSF3K_RS03505 63f6d477b144513bdf1b39ae3a8df89c 386 Gene3D G3DSA:1.10.150.130 64 182 6.5E-16 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SPSF3K_RS03505 63f6d477b144513bdf1b39ae3a8df89c 386 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 69 124 9.2E-14 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 353 1.4E-144 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 Gene3D G3DSA:3.50.30.20 1 149 5.6E-60 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 356 47.613 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00096 Glutamine amidotransferase superfamily signature 215 224 1.7E-11 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 253 1.7E-11 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 1.7E-11 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 SMART SM01097 2 132 1.9E-90 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 Pfam PF00117 Glutamine amidotransferase class-I 175 350 1.2E-45 T 29-03-2018 IPR017926 Glutamine amidotransferase SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 SUPERFAMILY SSF52021 2 145 7.45E-58 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 Gene3D G3DSA:3.40.50.880 177 362 2.2E-38 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 131 8.1E-54 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00097 Anthranilate synthase component II signature 242 253 8.8E-7 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00097 Anthranilate synthase component II signature 215 224 8.8E-7 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00097 Anthranilate synthase component II signature 327 340 8.8E-7 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 SUPERFAMILY SSF52317 140 353 1.8E-58 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 284 295 1.9E-34 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 173 187 1.9E-34 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 276 1.9E-34 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 242 258 1.9E-34 T 29-03-2018 SPSF3K_RS05225 1995f7c20f7008a4de936928efa4c51b 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 212 226 1.9E-34 T 29-03-2018 SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 SUPERFAMILY SSF56801 5 508 1.31E-111 T 29-03-2018 SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 499 9.4E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 Gene3D G3DSA:3.40.50.980 152 306 3.9E-34 T 29-03-2018 SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 511 256.554 T 29-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 Pfam PF00501 AMP-binding enzyme 25 407 5.9E-79 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 29-03-2018 IPR020845 AMP-binding, conserved site SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 30 431 1.4E-103 T 29-03-2018 IPR010071 Amino acid adenylation domain SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 Gene3D G3DSA:3.30.300.30 401 512 8.1E-22 T 29-03-2018 SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 4 511 1.1E-219 T 29-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 Gene3D G3DSA:2.30.38.10 307 400 1.8E-19 T 29-03-2018 SPSF3K_RS08260 8e61441aa78f352456bee72893064ae1 512 Gene3D G3DSA:3.40.50.980 3 151 2.0E-23 T 29-03-2018 SPSF3K_RS03340 5a4c5ef891be77694fab9540a20a91bf 173 Gene3D G3DSA:3.60.21.10 2 173 2.7E-22 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS03340 5a4c5ef891be77694fab9540a20a91bf 173 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 6 149 1.4E-24 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 SPSF3K_RS03340 5a4c5ef891be77694fab9540a20a91bf 173 SUPERFAMILY SSF56300 5 171 3.34E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS03340 5a4c5ef891be77694fab9540a20a91bf 173 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 149 1.1E-20 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 SPSF3K_RS00170 17cfe5c4e62e34e22d32699147e0d363 68 Pfam PF05154 TM2 domain 2 53 5.3E-18 T 29-03-2018 IPR007829 TM2 domain SPSF3K_RS05970 415b4c730b92d775b1ff35fbb88f2a49 309 SUPERFAMILY SSF53613 2 289 1.56E-62 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS05970 415b4c730b92d775b1ff35fbb88f2a49 309 Gene3D G3DSA:3.40.1190.20 43 309 7.1E-43 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS05970 415b4c730b92d775b1ff35fbb88f2a49 309 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SPSF3K_RS05970 415b4c730b92d775b1ff35fbb88f2a49 309 Pfam PF00294 pfkB family carbohydrate kinase 12 291 3.4E-57 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SPSF3K_RS05970 415b4c730b92d775b1ff35fbb88f2a49 309 Hamap MF_01557 Tagatose-6-phosphate kinase [lacC]. 1 309 58.759 T 29-03-2018 IPR005926 Tagatose-6-phosphate kinase GO:0009024|GO:0019512 KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 SPSF3K_RS05970 415b4c730b92d775b1ff35fbb88f2a49 309 Gene3D G3DSA:2.20.150.10 9 42 5.1E-14 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain SPSF3K_RS05970 415b4c730b92d775b1ff35fbb88f2a49 309 TIGRFAM TIGR01231 lacC: tagatose-6-phosphate kinase 2 309 2.4E-144 T 29-03-2018 IPR005926 Tagatose-6-phosphate kinase GO:0009024|GO:0019512 KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 SPSF3K_RS05970 415b4c730b92d775b1ff35fbb88f2a49 309 PIRSF PIRSF000535 1 309 1.0E-133 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPSF3K_RS05970 415b4c730b92d775b1ff35fbb88f2a49 309 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 307 7.4E-93 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPSF3K_RS08620 f48670ba5becf0b62b565b4c088a39f1 212 Gene3D G3DSA:1.10.150.240 15 75 8.9E-8 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SPSF3K_RS08620 f48670ba5becf0b62b565b4c088a39f1 212 SUPERFAMILY SSF56784 1 209 1.71E-51 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08620 f48670ba5becf0b62b565b4c088a39f1 212 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 5 184 2.5E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS08620 f48670ba5becf0b62b565b4c088a39f1 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 5.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS08620 f48670ba5becf0b62b565b4c088a39f1 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 5.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS08620 f48670ba5becf0b62b565b4c088a39f1 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 5.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS08620 f48670ba5becf0b62b565b4c088a39f1 212 Gene3D G3DSA:3.40.50.1000 76 212 1.4E-30 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08620 f48670ba5becf0b62b565b4c088a39f1 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 1.7E-35 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS06880 e76e3a9fcde4a80da259e5255273b2cc 284 SUPERFAMILY SSF52540 10 192 4.71E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06880 e76e3a9fcde4a80da259e5255273b2cc 284 PIRSF PIRSF006230 1 278 1.8E-97 T 29-03-2018 IPR016478 GTPase, MTG1 SPSF3K_RS06880 e76e3a9fcde4a80da259e5255273b2cc 284 Gene3D G3DSA:3.40.50.300 6 98 4.0E-10 T 29-03-2018 SPSF3K_RS06880 e76e3a9fcde4a80da259e5255273b2cc 284 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 185 4.0E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS06880 e76e3a9fcde4a80da259e5255273b2cc 284 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 124 144 4.0E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS06880 e76e3a9fcde4a80da259e5255273b2cc 284 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 4 274 7.0E-108 T 29-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis SPSF3K_RS06880 e76e3a9fcde4a80da259e5255273b2cc 284 Pfam PF01926 50S ribosome-binding GTPase 124 194 2.0E-15 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS06880 e76e3a9fcde4a80da259e5255273b2cc 284 Gene3D G3DSA:3.40.50.300 99 190 7.7E-21 T 29-03-2018 SPSF3K_RS06880 e76e3a9fcde4a80da259e5255273b2cc 284 Gene3D G3DSA:1.10.1580.10 191 268 9.1E-14 T 29-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain SPSF3K_RS04870 18f0450baa6056ba7097b88ce261c274 476 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 475 1.2E-176 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 SPSF3K_RS04870 18f0450baa6056ba7097b88ce261c274 476 Hamap MF_00484 Glycogen synthase [glgA]. 1 475 44.822 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 SPSF3K_RS04870 18f0450baa6056ba7097b88ce261c274 476 Gene3D G3DSA:3.40.50.2000 257 471 7.8E-32 T 29-03-2018 SPSF3K_RS04870 18f0450baa6056ba7097b88ce261c274 476 Gene3D G3DSA:3.40.50.2000 13 256 8.3E-8 T 29-03-2018 SPSF3K_RS04870 18f0450baa6056ba7097b88ce261c274 476 SUPERFAMILY SSF53756 3 475 5.58E-124 T 29-03-2018 SPSF3K_RS04870 18f0450baa6056ba7097b88ce261c274 476 Pfam PF08323 Starch synthase catalytic domain 2 236 1.4E-83 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 SPSF3K_RS04870 18f0450baa6056ba7097b88ce261c274 476 Pfam PF00534 Glycosyl transferases group 1 285 417 9.5E-14 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 Gene3D G3DSA:3.40.50.300 2 272 1.1E-49 T 29-03-2018 SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 Gene3D G3DSA:3.40.50.300 288 555 5.5E-47 T 29-03-2018 SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 SUPERFAMILY SSF52540 309 545 1.4E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 SMART SM00382 28 245 1.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 SMART SM00382 351 526 5.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 SUPERFAMILY SSF52540 132 249 4.54E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 SUPERFAMILY SSF52540 4 94 4.54E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 Pfam PF12848 ABC transporter 231 311 2.1E-23 T 29-03-2018 IPR032781 ABC-transporter extension domain SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 Pfam PF00005 ABC transporter 20 191 1.5E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 Pfam PF00005 ABC transporter 344 472 3.0E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08015 47b2772493c6ec9b02b5603c3eca3fa4 636 ProSitePatterns PS00211 ABC transporters family signature. 444 458 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS04570 e2433bf8157c691a9876e4942772bc43 465 Gene3D G3DSA:3.60.60.10 1 291 6.1E-51 T 29-03-2018 SPSF3K_RS04570 e2433bf8157c691a9876e4942772bc43 465 Pfam PF03577 Peptidase family C69 3 402 1.1E-195 T 29-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 SPSF3K_RS03510 45cbd3da5084ddff90d10f1c00c87c69 317 Gene3D G3DSA:3.20.20.70 1 287 4.7E-27 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS03510 45cbd3da5084ddff90d10f1c00c87c69 317 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 4 304 6.5E-105 T 29-03-2018 IPR005911 Protein YhcC-like GO:0051536 SPSF3K_RS03510 45cbd3da5084ddff90d10f1c00c87c69 317 Pfam PF16199 Radical_SAM C-terminal domain 212 295 7.3E-25 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 SPSF3K_RS03510 45cbd3da5084ddff90d10f1c00c87c69 317 SUPERFAMILY SSF102114 7 306 4.45E-43 T 29-03-2018 SPSF3K_RS03510 45cbd3da5084ddff90d10f1c00c87c69 317 Pfam PF04055 Radical SAM superfamily 41 204 2.9E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SPSF3K_RS03510 45cbd3da5084ddff90d10f1c00c87c69 317 SMART SM00729 21 251 4.4E-29 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 SMART SM00649 9 140 5.3E-84 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 SUPERFAMILY SSF54747 3 72 1.57E-29 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.277 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 6.0E-16 T 29-03-2018 SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 4.3E-63 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 Gene3D G3DSA:1.10.10.250 72 140 1.4E-24 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 SUPERFAMILY SSF46906 67 139 3.53E-27 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.2E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 Gene3D G3DSA:3.30.1550.10 3 71 5.6E-35 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 4.1E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal SPSF3K_RS03835 e24615f3339e356aae52b9e5e02054df 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10865 c412f00f052ce0e2391fb67edd5cb048 428 SUPERFAMILY SSF56601 83 426 1.55E-31 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS10865 c412f00f052ce0e2391fb67edd5cb048 428 Pfam PF13354 Beta-lactamase enzyme family 214 405 2.4E-29 T 29-03-2018 SPSF3K_RS10865 c412f00f052ce0e2391fb67edd5cb048 428 Gene3D G3DSA:3.40.710.10 190 427 3.7E-13 T 29-03-2018 SPSF3K_RS07635 347a4e3dbf406648b8902abdb1959b7c 166 Pfam PF01161 Phosphatidylethanolamine-binding protein 26 160 1.6E-27 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SPSF3K_RS07635 347a4e3dbf406648b8902abdb1959b7c 166 Gene3D G3DSA:3.90.280.10 1 166 1.0E-35 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SPSF3K_RS07635 347a4e3dbf406648b8902abdb1959b7c 166 SUPERFAMILY SSF49777 8 157 2.35E-31 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein SPSF3K_RS07635 347a4e3dbf406648b8902abdb1959b7c 166 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 23 161 1.8E-33 T 29-03-2018 IPR005247 YbhB/YbcL SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 577 7.1E-234 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 Gene3D G3DSA:3.30.930.10 339 581 1.3E-53 T 29-03-2018 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 Pfam PF01336 OB-fold nucleic acid binding domain 20 103 4.4E-17 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 Gene3D G3DSA:2.40.50.140 1 109 4.1E-26 T 29-03-2018 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 SUPERFAMILY SSF55681 115 295 8.36E-104 T 29-03-2018 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 SUPERFAMILY SSF55681 419 579 8.36E-104 T 29-03-2018 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 579 33.586 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 SUPERFAMILY SSF50249 2 110 7.62E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 Pfam PF02938 GAD domain 312 400 3.1E-23 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 SUPERFAMILY SSF55261 292 413 9.81E-36 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 Pfam PF00152 tRNA synthetases class II (D, K and N) 121 552 7.8E-105 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 210 223 8.9E-24 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 513 527 8.9E-24 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 205 8.9E-24 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 469 485 8.9E-24 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00310 842d310c8dae419a08c5dab1c330cb67 582 Gene3D G3DSA:3.30.930.10 135 338 2.8E-43 T 29-03-2018 SPSF3K_RS04235 34f7c652193bcb29535fa7f8db563475 250 Pfam PF00005 ABC transporter 19 175 9.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS04235 34f7c652193bcb29535fa7f8db563475 250 Gene3D G3DSA:3.40.50.300 1 248 5.4E-63 T 29-03-2018 SPSF3K_RS04235 34f7c652193bcb29535fa7f8db563475 250 SMART SM00382 28 230 1.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS04235 34f7c652193bcb29535fa7f8db563475 250 SUPERFAMILY SSF52540 4 237 1.18E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04235 34f7c652193bcb29535fa7f8db563475 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS04235 34f7c652193bcb29535fa7f8db563475 250 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 4 250 5.1E-130 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 SPSF3K_RS02115 25d1513f84eb3b9f196e7e2498c8ee8d 804 Pfam PF02901 Pyruvate formate lyase-like 12 665 1.1E-211 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 SPSF3K_RS02115 25d1513f84eb3b9f196e7e2498c8ee8d 804 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 11 803 1.0E-277 T 29-03-2018 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 SPSF3K_RS02115 25d1513f84eb3b9f196e7e2498c8ee8d 804 Gene3D G3DSA:3.20.70.20 11 804 9.4E-286 T 29-03-2018 SPSF3K_RS02115 25d1513f84eb3b9f196e7e2498c8ee8d 804 ProSitePatterns PS00850 Glycine radical domain signature. 775 783 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site SPSF3K_RS02115 25d1513f84eb3b9f196e7e2498c8ee8d 804 SUPERFAMILY SSF51998 9 803 6.1E-233 T 29-03-2018 SPSF3K_RS02115 25d1513f84eb3b9f196e7e2498c8ee8d 804 Pfam PF01228 Glycine radical 682 786 9.4E-30 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PIRSF PIRSF000532 1 323 5.9E-115 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 Gene3D G3DSA:3.40.50.450 203 300 4.7E-13 T 29-03-2018 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 1.1E-120 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 Gene3D G3DSA:3.40.50.450 1 202 3.2E-80 T 29-03-2018 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 336 46.734 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.3E-84 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 2.3E-84 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.3E-84 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 241 263 2.3E-84 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.3E-84 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 2.3E-84 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.3E-84 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.3E-84 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.3E-84 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 Pfam PF00365 Phosphofructokinase 3 277 6.3E-105 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 SUPERFAMILY SSF53784 1 299 4.84E-106 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS07265 5aa096a04632bce9f6841cd84578e74f 337 ProSitePatterns PS00433 Phosphofructokinase signature. 245 263 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 SPSF3K_RS03720 0e79a7ad1911f31b87a8cbebf6ce8c5f 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 4.7E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS03720 0e79a7ad1911f31b87a8cbebf6ce8c5f 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 4.7E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS03720 0e79a7ad1911f31b87a8cbebf6ce8c5f 93 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 4.7E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS03720 0e79a7ad1911f31b87a8cbebf6ce8c5f 93 Gene3D G3DSA:1.10.10.10 1 79 3.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03720 0e79a7ad1911f31b87a8cbebf6ce8c5f 93 SUPERFAMILY SSF46785 2 83 3.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03720 0e79a7ad1911f31b87a8cbebf6ce8c5f 93 Pfam PF12840 Helix-turn-helix domain 5 61 5.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03720 0e79a7ad1911f31b87a8cbebf6ce8c5f 93 SMART SM00418 5 83 1.7E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS06335 f7f4fc50142a61f7c8d0d9304868c8f4 327 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 166 178 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 SPSF3K_RS06335 f7f4fc50142a61f7c8d0d9304868c8f4 327 PIRSF PIRSF036500 3 327 2.2E-191 T 29-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 SPSF3K_RS06335 f7f4fc50142a61f7c8d0d9304868c8f4 327 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 311 6.3E-68 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SPSF3K_RS06335 f7f4fc50142a61f7c8d0d9304868c8f4 327 SUPERFAMILY SSF51412 5 316 2.09E-91 T 29-03-2018 SPSF3K_RS06335 f7f4fc50142a61f7c8d0d9304868c8f4 327 SMART SM01240 6 327 6.4E-106 T 29-03-2018 SPSF3K_RS06335 f7f4fc50142a61f7c8d0d9304868c8f4 327 Hamap MF_01511 GMP reductase [guaC]. 5 326 62.05 T 29-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 SPSF3K_RS06335 f7f4fc50142a61f7c8d0d9304868c8f4 327 Gene3D G3DSA:3.20.20.70 4 327 1.5E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS06335 f7f4fc50142a61f7c8d0d9304868c8f4 327 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 7 325 9.6E-202 T 29-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 SPSF3K_RS08800 07a2b7c0a4d43eeb6cc05a3b89f0a7ae 553 PIRSF PIRSF003128 1 553 3.0E-176 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SPSF3K_RS08800 07a2b7c0a4d43eeb6cc05a3b89f0a7ae 553 SUPERFAMILY SSF52540 2 50 1.33E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08800 07a2b7c0a4d43eeb6cc05a3b89f0a7ae 553 SUPERFAMILY SSF52540 312 506 1.33E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08800 07a2b7c0a4d43eeb6cc05a3b89f0a7ae 553 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 551 9.0E-165 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SPSF3K_RS08800 07a2b7c0a4d43eeb6cc05a3b89f0a7ae 553 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 509 1.6E-19 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SPSF3K_RS08800 07a2b7c0a4d43eeb6cc05a3b89f0a7ae 553 Gene3D G3DSA:3.40.50.300 224 524 2.0E-19 T 29-03-2018 SPSF3K_RS08800 07a2b7c0a4d43eeb6cc05a3b89f0a7ae 553 Gene3D G3DSA:3.40.50.300 1 182 2.8E-26 T 29-03-2018 SPSF3K_RS08800 07a2b7c0a4d43eeb6cc05a3b89f0a7ae 553 SUPERFAMILY SSF52540 1 219 7.55E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09605 df5bb94db62ca1791b158f430778b08b 210 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 2.5E-7 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal SPSF3K_RS09605 df5bb94db62ca1791b158f430778b08b 210 SUPERFAMILY SSF54211 2 128 2.47E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS09605 df5bb94db62ca1791b158f430778b08b 210 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 29-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site SPSF3K_RS09605 df5bb94db62ca1791b158f430778b08b 210 Pfam PF01205 Uncharacterized protein family UPF0029 18 123 1.2E-31 T 29-03-2018 IPR001498 Impact, N-terminal SPSF3K_RS09605 df5bb94db62ca1791b158f430778b08b 210 SUPERFAMILY SSF54980 137 201 4.6E-6 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS09605 df5bb94db62ca1791b158f430778b08b 210 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 198 6.8E-60 T 29-03-2018 IPR015796 Impact family, bacterial/archaeal SPSF3K_RS09605 df5bb94db62ca1791b158f430778b08b 210 Gene3D G3DSA:3.30.70.240 134 197 2.4E-7 T 29-03-2018 SPSF3K_RS09605 df5bb94db62ca1791b158f430778b08b 210 Gene3D G3DSA:3.30.230.30 3 132 3.0E-45 T 29-03-2018 IPR001498 Impact, N-terminal SPSF3K_RS08975 532a6f680cf232dd5bae552da05b70ba 584 Pfam PF00664 ABC transporter transmembrane region 26 294 3.2E-38 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS08975 532a6f680cf232dd5bae552da05b70ba 584 SMART SM00382 365 566 4.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08975 532a6f680cf232dd5bae552da05b70ba 584 SUPERFAMILY SSF52540 334 574 5.22E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08975 532a6f680cf232dd5bae552da05b70ba 584 Gene3D G3DSA:3.40.50.300 328 579 1.8E-74 T 29-03-2018 SPSF3K_RS08975 532a6f680cf232dd5bae552da05b70ba 584 SUPERFAMILY SSF90123 11 325 1.26E-71 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS08975 532a6f680cf232dd5bae552da05b70ba 584 Gene3D G3DSA:1.20.1560.10 4 327 1.6E-69 T 29-03-2018 SPSF3K_RS08975 532a6f680cf232dd5bae552da05b70ba 584 Pfam PF00005 ABC transporter 356 504 4.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS10435 812ebb7a6049d71a90dd2b441e8509a1 164 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site SPSF3K_RS10435 812ebb7a6049d71a90dd2b441e8509a1 164 Pfam PF00333 Ribosomal protein S5, N-terminal domain 10 74 2.8E-32 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10435 812ebb7a6049d71a90dd2b441e8509a1 164 Gene3D G3DSA:3.30.230.10 75 164 8.5E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS10435 812ebb7a6049d71a90dd2b441e8509a1 164 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 156 3.4E-28 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10435 812ebb7a6049d71a90dd2b441e8509a1 164 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 35.812 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPSF3K_RS10435 812ebb7a6049d71a90dd2b441e8509a1 164 SUPERFAMILY SSF54768 8 75 4.81E-25 T 29-03-2018 SPSF3K_RS10435 812ebb7a6049d71a90dd2b441e8509a1 164 SUPERFAMILY SSF54211 79 157 6.57E-25 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS10435 812ebb7a6049d71a90dd2b441e8509a1 164 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 162 7.7E-68 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPSF3K_RS10435 812ebb7a6049d71a90dd2b441e8509a1 164 Gene3D G3DSA:3.30.160.20 9 71 2.0E-30 T 29-03-2018 SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 135 3.8E-43 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 SUPERFAMILY SSF52283 1 135 5.7E-62 T 29-03-2018 SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 SUPERFAMILY SSF52283 304 358 5.7E-62 T 29-03-2018 SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 PIRSF PIRSF000183 1 368 3.8E-174 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 Gene3D G3DSA:3.40.50.720 1 184 1.1E-39 T 29-03-2018 SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 Gene3D G3DSA:3.40.50.720 185 368 1.4E-44 T 29-03-2018 SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 SMART SM01002 147 296 2.4E-80 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 171 196 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 SUPERFAMILY SSF51735 135 302 6.23E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 367 4.7E-159 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 SMART SM01003 4 135 2.9E-69 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal SPSF3K_RS08195 cecc6ab0b41c0cc416eec924a1ae0844 368 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 139 352 1.8E-80 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 SUPERFAMILY SSF52374 108 443 2.17E-100 T 29-03-2018 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 SMART SM01016 1 83 6.7E-27 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 Gene3D G3DSA:3.30.1360.70 1 104 5.2E-26 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 Gene3D G3DSA:3.40.50.620 105 429 1.7E-62 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 Gene3D G3DSA:1.10.730.10 430 562 1.1E-45 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 562 27.155 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 Pfam PF05746 DALR anticodon binding domain 449 562 3.0E-33 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 SUPERFAMILY SSF55190 1 104 3.53E-26 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 4 83 2.3E-18 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 Pfam PF00750 tRNA synthetases class I (R) 95 434 1.3E-97 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 4 562 4.0E-160 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 128 144 3.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 296 317 3.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 113 128 3.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 152 165 3.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 SUPERFAMILY SSF47323 443 562 9.68E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00330 d7c6d857643a212a5942f6e0f17b2d1c 562 SMART SM00836 449 562 2.3E-43 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 Gene3D G3DSA:3.40.1110.10 326 432 1.5E-21 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 311 317 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 66 610 3.2E-167 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 SUPERFAMILY SSF56784 307 327 1.08E-45 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 SUPERFAMILY SSF56784 363 607 1.08E-45 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 SUPERFAMILY SSF81653 125 217 4.45E-24 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 Gene3D G3DSA:3.40.50.1000 433 573 4.1E-39 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 SUPERFAMILY SSF81665 556 586 3.27E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 SUPERFAMILY SSF81665 218 303 3.27E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 SUPERFAMILY SSF81665 71 120 3.27E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 1.2E-22 T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 542 1.2E-22 T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 431 442 1.2E-22 T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 309 323 1.2E-22 T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 526 1.2E-22 T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 ProSitePatterns PS01229 Hypothetical cof family signature 2. 507 529 - T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 Pfam PF00702 haloacid dehalogenase-like hydrolase 305 521 8.7E-35 T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 Gene3D G3DSA:1.20.1110.10 53 325 3.2E-34 T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 52 610 1.5E-125 T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 Pfam PF00122 E1-E2 ATPase 117 289 1.7E-46 T 29-03-2018 SPSF3K_RS05785 d6e3ce82299bee902eeaa0dd74c14e55 634 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 594 1.8E-75 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS05380 af15df8345b7af49a9b5ecd540a72863 589 Gene3D G3DSA:3.40.50.300 335 589 1.4E-73 T 29-03-2018 SPSF3K_RS05380 af15df8345b7af49a9b5ecd540a72863 589 SMART SM00382 374 546 6.7E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05380 af15df8345b7af49a9b5ecd540a72863 589 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS05380 af15df8345b7af49a9b5ecd540a72863 589 Pfam PF00005 ABC transporter 366 514 2.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS05380 af15df8345b7af49a9b5ecd540a72863 589 SUPERFAMILY SSF52540 338 585 1.51E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05380 af15df8345b7af49a9b5ecd540a72863 589 Pfam PF00664 ABC transporter transmembrane region 22 303 1.7E-48 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS05380 af15df8345b7af49a9b5ecd540a72863 589 Gene3D G3DSA:1.20.1560.10 2 334 1.3E-72 T 29-03-2018 SPSF3K_RS05380 af15df8345b7af49a9b5ecd540a72863 589 SUPERFAMILY SSF90123 8 332 9.03E-75 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS10575 8b6b0f195c033188d3b1af85466bdaf8 361 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 6 354 4.4E-112 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SPSF3K_RS10575 8b6b0f195c033188d3b1af85466bdaf8 361 Gene3D G3DSA:3.40.50.20 4 89 8.6E-25 T 29-03-2018 SPSF3K_RS10575 8b6b0f195c033188d3b1af85466bdaf8 361 Gene3D G3DSA:3.30.1490.20 117 178 1.3E-11 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPSF3K_RS10575 8b6b0f195c033188d3b1af85466bdaf8 361 Pfam PF02222 ATP-grasp domain 111 276 1.2E-46 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type SPSF3K_RS10575 8b6b0f195c033188d3b1af85466bdaf8 361 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 6 351 41.063 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SPSF3K_RS10575 8b6b0f195c033188d3b1af85466bdaf8 361 Gene3D G3DSA:3.30.470.20 179 357 1.7E-38 T 29-03-2018 SPSF3K_RS10575 8b6b0f195c033188d3b1af85466bdaf8 361 SUPERFAMILY SSF56059 101 296 4.28E-55 T 29-03-2018 SPSF3K_RS10575 8b6b0f195c033188d3b1af85466bdaf8 361 SUPERFAMILY SSF52440 3 89 2.59E-24 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SPSF3K_RS10575 8b6b0f195c033188d3b1af85466bdaf8 361 SUPERFAMILY SSF51246 300 355 8.63E-16 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SPSF3K_RS04440 728bbc6254596cabfad9bf40674eddec 252 Pfam PF00121 Triosephosphate isomerase 6 247 5.7E-91 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS04440 728bbc6254596cabfad9bf40674eddec 252 SUPERFAMILY SSF51351 3 250 6.28E-89 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS04440 728bbc6254596cabfad9bf40674eddec 252 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 242 4.2E-58 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS04440 728bbc6254596cabfad9bf40674eddec 252 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 251 39.528 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS04440 728bbc6254596cabfad9bf40674eddec 252 Gene3D G3DSA:3.20.20.70 1 252 1.3E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS04440 728bbc6254596cabfad9bf40674eddec 252 ProSitePatterns PS00171 Triosephosphate isomerase active site. 166 176 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00165 3f7693fe5c733afd72e7c53a5f15f11b 54 Gene3D G3DSA:1.10.1470.10 1 54 3.9E-11 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS00165 3f7693fe5c733afd72e7c53a5f15f11b 54 SUPERFAMILY SSF69047 1 52 2.22E-9 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS00100 eef955bf1047fdb85b5f4efd1e4acef2 268 Pfam PF02361 Cobalt transport protein 14 234 6.4E-48 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component SPSF3K_RS00100 eef955bf1047fdb85b5f4efd1e4acef2 268 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 1 264 36.232 T 29-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 SPSF3K_RS09635 9d0bacf556f6ecd67b7e9ac12d675804 231 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 115 228 6.8E-35 T 29-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF SPSF3K_RS09635 9d0bacf556f6ecd67b7e9ac12d675804 231 PIRSF PIRSF031509 1 231 7.6E-81 T 29-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 SPSF3K_RS09380 9bc836e8704cd87c628c092eab9d6708 306 SUPERFAMILY SSF51556 3 301 1.36E-47 T 29-03-2018 IPR032466 Metal-dependent hydrolase SPSF3K_RS09380 9bc836e8704cd87c628c092eab9d6708 306 Pfam PF04909 Amidohydrolase 4 296 9.0E-22 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SPSF3K_RS09380 9bc836e8704cd87c628c092eab9d6708 306 Gene3D G3DSA:3.20.20.140 1 304 7.0E-43 T 29-03-2018 SPSF3K_RS03645 dab95c8e84dabb857e8ce67182e9538d 266 Pfam PF04468 PSP1 C-terminal conserved region 61 145 3.6E-20 T 29-03-2018 IPR007557 PSP1, C-terminal SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 Pfam PF00455 DeoR C terminal sensor domain 80 236 3.0E-45 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 Gene3D G3DSA:1.10.10.10 1 58 5.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 SUPERFAMILY SSF100950 80 236 2.26E-28 T 29-03-2018 SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 SMART SM01134 78 237 2.6E-57 T 29-03-2018 SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 Gene3D G3DSA:3.40.50.1360 70 239 5.2E-30 T 29-03-2018 SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 SMART SM00420 6 58 1.2E-22 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 Pfam PF08220 DeoR-like helix-turn-helix domain 6 62 3.8E-20 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.1E-10 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.1E-10 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS05955 4f988bf4f222a94fa4559c8dbe02cfef 257 SUPERFAMILY SSF46785 4 62 9.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05475 53f5e0509576c47c74fe101cb52d1d9e 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 1.9E-28 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05475 53f5e0509576c47c74fe101cb52d1d9e 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 1.1E-43 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05475 53f5e0509576c47c74fe101cb52d1d9e 121 SUPERFAMILY SSF54736 52 121 2.09E-22 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SPSF3K_RS05475 53f5e0509576c47c74fe101cb52d1d9e 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 23.906 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05475 53f5e0509576c47c74fe101cb52d1d9e 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 2.0E-9 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05475 53f5e0509576c47c74fe101cb52d1d9e 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 1.3E-18 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05475 53f5e0509576c47c74fe101cb52d1d9e 121 Gene3D G3DSA:1.20.5.710 3 50 1.3E-13 T 29-03-2018 SPSF3K_RS05475 53f5e0509576c47c74fe101cb52d1d9e 121 Gene3D G3DSA:3.30.1390.10 51 121 6.6E-27 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SPSF3K_RS05475 53f5e0509576c47c74fe101cb52d1d9e 121 SUPERFAMILY SSF48300 3 51 9.94E-14 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05775 e52d24e3a4b08daa44b441aac13fe934 284 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SPSF3K_RS05775 e52d24e3a4b08daa44b441aac13fe934 284 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 9 258 3.1E-68 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SPSF3K_RS05775 e52d24e3a4b08daa44b441aac13fe934 284 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 263 16.87 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SPSF3K_RS05775 e52d24e3a4b08daa44b441aac13fe934 284 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 257 8.0E-77 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SPSF3K_RS01035 c7857e09430ab250ea378f8e1269d1bb 308 Pfam PF14804 Jag N-terminus 4 51 1.0E-16 T 29-03-2018 IPR032782 Jag, N-terminal SPSF3K_RS01035 c7857e09430ab250ea378f8e1269d1bb 308 Pfam PF13083 KH domain 165 233 5.6E-15 T 29-03-2018 SPSF3K_RS01035 c7857e09430ab250ea378f8e1269d1bb 308 SUPERFAMILY SSF82708 248 305 1.41E-10 T 29-03-2018 IPR001374 R3H domain GO:0003676 SPSF3K_RS01035 c7857e09430ab250ea378f8e1269d1bb 308 Pfam PF01424 R3H domain 246 305 4.9E-14 T 29-03-2018 IPR001374 R3H domain GO:0003676 SPSF3K_RS01035 c7857e09430ab250ea378f8e1269d1bb 308 Gene3D G3DSA:3.30.300.20 160 242 1.4E-12 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS01035 c7857e09430ab250ea378f8e1269d1bb 308 SMART SM01245 3 54 4.5E-19 T 29-03-2018 IPR032782 Jag, N-terminal SPSF3K_RS01035 c7857e09430ab250ea378f8e1269d1bb 308 Gene3D G3DSA:3.30.30.80 1 51 9.7E-19 T 29-03-2018 SPSF3K_RS01035 c7857e09430ab250ea378f8e1269d1bb 308 Gene3D G3DSA:3.30.1370.50 243 308 8.4E-18 T 29-03-2018 IPR001374 R3H domain GO:0003676 SPSF3K_RS01035 c7857e09430ab250ea378f8e1269d1bb 308 SMART SM00393 228 307 1.2E-12 T 29-03-2018 IPR001374 R3H domain GO:0003676 SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 3.8E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 3.8E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 3.8E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 3.8E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 3.8E-16 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 368 376 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 SUPERFAMILY SSF51445 2 471 4.1E-147 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 Gene3D G3DSA:3.20.20.80 1 475 8.0E-141 T 29-03-2018 SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 Pfam PF00232 Glycosyl hydrolase family 1 2 471 5.6E-125 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06675 0faeba5de8100228ab3a8cecc52a1831 476 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPSF3K_RS06425 e5ae4e10aa3267fee191781211e0af9a 137 Gene3D G3DSA:3.10.180.10 1 137 1.1E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS06425 e5ae4e10aa3267fee191781211e0af9a 137 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 SPSF3K_RS06425 e5ae4e10aa3267fee191781211e0af9a 137 SUPERFAMILY SSF54593 1 137 1.38E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS06425 e5ae4e10aa3267fee191781211e0af9a 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 135 4.3E-16 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 516 540 1.8E-7 T 29-03-2018 IPR023908 xxxLxxG heptad repeat SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 529 556 1.2E-4 T 29-03-2018 IPR023908 xxxLxxG heptad repeat SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 553 577 7.9E-5 T 29-03-2018 IPR023908 xxxLxxG heptad repeat SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 564 591 1.5E-4 T 29-03-2018 IPR023908 xxxLxxG heptad repeat SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 571 598 2.2E-5 T 29-03-2018 IPR023908 xxxLxxG heptad repeat SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 240 265 8.9E-5 T 29-03-2018 IPR023908 xxxLxxG heptad repeat SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 212 238 1.7E-8 T 29-03-2018 IPR023908 xxxLxxG heptad repeat SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 3 166 1.1E-59 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 631 831 1.5E-60 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 Gene3D G3DSA:1.10.287.950 212 295 4.1E-10 T 29-03-2018 SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 Gene3D G3DSA:1.10.287.950 542 622 5.0E-7 T 29-03-2018 SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 Gene3D G3DSA:3.40.1710.10 41 205 2.0E-24 T 29-03-2018 SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 SUPERFAMILY SSF58104 178 288 4.05E-5 T 29-03-2018 SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 Gene3D G3DSA:1.20.120.570 372 541 2.5E-5 T 29-03-2018 SPSF3K_RS02810 c79bb00e5e9353d37fde3a16644b52a9 833 Gene3D G3DSA:1.20.120.570 296 371 0.036 T 29-03-2018 SPSF3K_RS11060 c7fb970df52a6c4fd96565cffdc7d456 175 Gene3D G3DSA:3.40.630.30 2 175 3.5E-23 T 29-03-2018 SPSF3K_RS11060 c7fb970df52a6c4fd96565cffdc7d456 175 Pfam PF13302 Acetyltransferase (GNAT) domain 9 146 1.0E-28 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS11060 c7fb970df52a6c4fd96565cffdc7d456 175 SUPERFAMILY SSF55729 2 171 4.7E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS10980 c7fb970df52a6c4fd96565cffdc7d456 175 Gene3D G3DSA:3.40.630.30 2 175 3.5E-23 T 29-03-2018 SPSF3K_RS10980 c7fb970df52a6c4fd96565cffdc7d456 175 Pfam PF13302 Acetyltransferase (GNAT) domain 9 146 1.0E-28 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS10980 c7fb970df52a6c4fd96565cffdc7d456 175 SUPERFAMILY SSF55729 2 171 4.7E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS10470 6312a58c7d295c2d11a5bfbf7fa9d9c1 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 6.9E-57 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 SPSF3K_RS10470 6312a58c7d295c2d11a5bfbf7fa9d9c1 122 Gene3D G3DSA:2.40.150.20 1 122 6.3E-52 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10470 6312a58c7d295c2d11a5bfbf7fa9d9c1 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.985 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10470 6312a58c7d295c2d11a5bfbf7fa9d9c1 122 SMART SM01374 1 122 1.1E-85 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10470 6312a58c7d295c2d11a5bfbf7fa9d9c1 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.6E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10470 6312a58c7d295c2d11a5bfbf7fa9d9c1 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10470 6312a58c7d295c2d11a5bfbf7fa9d9c1 122 SUPERFAMILY SSF50193 1 122 3.4E-50 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10080 05be7d2fce9457cff381eb51f1d2b6ac 159 Gene3D G3DSA:3.90.1170.30 79 116 1.5E-5 T 29-03-2018 SPSF3K_RS10080 05be7d2fce9457cff381eb51f1d2b6ac 159 SUPERFAMILY SSF51230 84 158 4.06E-22 T 29-03-2018 IPR011053 Single hybrid motif SPSF3K_RS10080 05be7d2fce9457cff381eb51f1d2b6ac 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 88 101 4.8E-12 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 SPSF3K_RS10080 05be7d2fce9457cff381eb51f1d2b6ac 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 120 133 4.8E-12 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 SPSF3K_RS10080 05be7d2fce9457cff381eb51f1d2b6ac 159 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 105 119 4.8E-12 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 SPSF3K_RS10080 05be7d2fce9457cff381eb51f1d2b6ac 159 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 115 132 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SPSF3K_RS10080 05be7d2fce9457cff381eb51f1d2b6ac 159 Pfam PF00364 Biotin-requiring enzyme 85 158 1.9E-19 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SPSF3K_RS10080 05be7d2fce9457cff381eb51f1d2b6ac 159 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 159 2.0E-34 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 SPSF3K_RS10080 05be7d2fce9457cff381eb51f1d2b6ac 159 Gene3D G3DSA:2.40.50.100 117 159 1.1E-17 T 29-03-2018 SPSF3K_RS03075 f55a20a73de4dbc9ac5a2c72f42b61d7 356 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 322 3.9E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SPSF3K_RS03075 f55a20a73de4dbc9ac5a2c72f42b61d7 356 Pfam PF00005 ABC transporter 29 187 3.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS03075 f55a20a73de4dbc9ac5a2c72f42b61d7 356 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS03075 f55a20a73de4dbc9ac5a2c72f42b61d7 356 SUPERFAMILY SSF52540 8 258 1.01E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03075 f55a20a73de4dbc9ac5a2c72f42b61d7 356 SMART SM00382 37 237 4.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS03075 f55a20a73de4dbc9ac5a2c72f42b61d7 356 Gene3D G3DSA:3.40.50.300 5 338 4.1E-69 T 29-03-2018 SPSF3K_RS03075 f55a20a73de4dbc9ac5a2c72f42b61d7 356 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 301 8.5E-11 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SPSF3K_RS01150 25483aabc2fb877d54f69266ff5295a9 290 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 273 2.9E-74 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SPSF3K_RS01150 25483aabc2fb877d54f69266ff5295a9 290 Pfam PF16745 RsgA N-terminal domain 2 55 5.9E-24 T 29-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal SPSF3K_RS01150 25483aabc2fb877d54f69266ff5295a9 290 SUPERFAMILY SSF52540 63 280 2.96E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01150 25483aabc2fb877d54f69266ff5295a9 290 Gene3D G3DSA:3.40.50.300 61 215 4.4E-20 T 29-03-2018 SPSF3K_RS01150 25483aabc2fb877d54f69266ff5295a9 290 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 1 280 37.579 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 SPSF3K_RS01150 25483aabc2fb877d54f69266ff5295a9 290 Pfam PF03193 RsgA GTPase 58 215 7.7E-57 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 SPSF3K_RS01150 25483aabc2fb877d54f69266ff5295a9 290 Gene3D G3DSA:1.10.40.50 218 285 4.6E-23 T 29-03-2018 SPSF3K_RS01150 25483aabc2fb877d54f69266ff5295a9 290 SUPERFAMILY SSF50249 2 62 5.4E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS01150 25483aabc2fb877d54f69266ff5295a9 290 Gene3D G3DSA:2.40.50.140 1 60 2.1E-20 T 29-03-2018 SPSF3K_RS04465 a1be30bfe4c4e3de7b91a3be5ea9dbff 128 Pfam PF09148 Domain of unknown function (DUF1934) 3 125 6.6E-21 T 29-03-2018 IPR015231 Protein of unknown function DUF1934 SPSF3K_RS04465 a1be30bfe4c4e3de7b91a3be5ea9dbff 128 Gene3D G3DSA:2.40.128.20 1 128 2.5E-26 T 29-03-2018 IPR012674 Calycin SPSF3K_RS04465 a1be30bfe4c4e3de7b91a3be5ea9dbff 128 SUPERFAMILY SSF50814 1 127 2.71E-29 T 29-03-2018 IPR012674 Calycin SPSF3K_RS03770 a7d409f14a18e6044084c44b690eecfc 320 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 200 1.4E-4 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS03770 a7d409f14a18e6044084c44b690eecfc 320 SUPERFAMILY SSF55347 131 291 1.64E-14 T 29-03-2018 SPSF3K_RS03770 a7d409f14a18e6044084c44b690eecfc 320 Gene3D G3DSA:3.30.360.10 144 320 1.5E-14 T 29-03-2018 SPSF3K_RS03770 a7d409f14a18e6044084c44b690eecfc 320 SUPERFAMILY SSF51735 2 153 9.63E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS03770 a7d409f14a18e6044084c44b690eecfc 320 Gene3D G3DSA:3.40.50.720 1 143 2.5E-35 T 29-03-2018 SPSF3K_RS03770 a7d409f14a18e6044084c44b690eecfc 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 7.8E-26 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SPSF3K_RS09935 b72fe4d48a75b4e3d39ebbb695bc10b8 116 SUPERFAMILY SSF89919 1 112 1.3E-29 T 29-03-2018 IPR023799 Ribosome-binding factor A domain SPSF3K_RS09935 b72fe4d48a75b4e3d39ebbb695bc10b8 116 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 114 2.0E-29 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SPSF3K_RS09935 b72fe4d48a75b4e3d39ebbb695bc10b8 116 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 96 9.0E-44 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SPSF3K_RS09935 b72fe4d48a75b4e3d39ebbb695bc10b8 116 Gene3D G3DSA:3.30.300.20 3 116 1.5E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS09935 b72fe4d48a75b4e3d39ebbb695bc10b8 116 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 116 21.109 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SPSF3K_RS09935 b72fe4d48a75b4e3d39ebbb695bc10b8 116 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 SPSF3K_RS09935 b72fe4d48a75b4e3d39ebbb695bc10b8 116 Pfam PF02033 Ribosome-binding factor A 5 109 5.4E-30 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 SPSF3K_RS01300 6a3b3419e2c3190ba8ce0ba18103415d 99 SUPERFAMILY SSF82607 4 94 1.44E-26 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPSF3K_RS01300 6a3b3419e2c3190ba8ce0ba18103415d 99 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 19.669 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPSF3K_RS01300 6a3b3419e2c3190ba8ce0ba18103415d 99 PIRSF PIRSF004555 1 99 8.5E-28 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPSF3K_RS01300 6a3b3419e2c3190ba8ce0ba18103415d 99 Gene3D G3DSA:3.30.1310.10 1 99 9.4E-29 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPSF3K_RS01300 6a3b3419e2c3190ba8ce0ba18103415d 99 Pfam PF02575 YbaB/EbfC DNA-binding family 8 97 2.8E-25 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPSF3K_RS01300 6a3b3419e2c3190ba8ce0ba18103415d 99 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 97 4.4E-22 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPSF3K_RS03305 45c14a0d5c878e1d2e50b171652b36c9 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 30 95 2.0E-10 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SPSF3K_RS03305 45c14a0d5c878e1d2e50b171652b36c9 247 SUPERFAMILY SSF55315 3 94 9.53E-19 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SPSF3K_RS03305 45c14a0d5c878e1d2e50b171652b36c9 247 Gene3D G3DSA:3.30.1330.30 4 95 2.5E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SPSF3K_RS03305 45c14a0d5c878e1d2e50b171652b36c9 247 SUPERFAMILY SSF75217 84 246 1.9E-41 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SPSF3K_RS03305 45c14a0d5c878e1d2e50b171652b36c9 247 SMART SM00967 30 96 7.7E-14 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SPSF3K_RS03305 45c14a0d5c878e1d2e50b171652b36c9 247 Gene3D G3DSA:3.40.1280.10 96 247 7.8E-40 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPSF3K_RS03305 45c14a0d5c878e1d2e50b171652b36c9 247 Pfam PF00588 SpoU rRNA Methylase family 105 243 8.0E-36 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 63 74 2.7E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 156 2.7E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 125 2.7E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 SUPERFAMILY SSF51735 3 231 1.05E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 Gene3D G3DSA:3.40.50.720 2 232 1.4E-59 T 29-03-2018 SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 230 2.7E-46 T 29-03-2018 SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 124 152 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.4E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 8.4E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 127 8.4E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 63 74 8.4E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 213 8.4E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS03765 25c2d8b035e9f303ec4dc1d9dcd5eec0 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 156 8.4E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS05420 4ba4261d988b1e6a8825c643db28948d 331 PIRSF PIRSF003314 1 331 1.8E-112 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 SPSF3K_RS05420 4ba4261d988b1e6a8825c643db28948d 331 SUPERFAMILY SSF51395 19 327 5.95E-73 T 29-03-2018 SPSF3K_RS05420 4ba4261d988b1e6a8825c643db28948d 331 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 1 324 34.126 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 SPSF3K_RS05420 4ba4261d988b1e6a8825c643db28948d 331 Gene3D G3DSA:3.20.20.70 1 331 8.9E-60 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS05420 4ba4261d988b1e6a8825c643db28948d 331 Pfam PF01070 FMN-dependent dehydrogenase 160 317 3.1E-21 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 SPSF3K_RS05420 4ba4261d988b1e6a8825c643db28948d 331 Pfam PF01070 FMN-dependent dehydrogenase 18 91 6.7E-6 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 SPSF3K_RS05420 4ba4261d988b1e6a8825c643db28948d 331 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 3 323 2.5E-117 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 SPSF3K_RS03780 f291b1d4f3ccc3bf4de3704fb1a7bf59 184 Gene3D G3DSA:3.90.79.10 1 181 4.1E-39 T 29-03-2018 SPSF3K_RS03780 f291b1d4f3ccc3bf4de3704fb1a7bf59 184 Pfam PF00293 NUDIX domain 42 158 5.2E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SPSF3K_RS03780 f291b1d4f3ccc3bf4de3704fb1a7bf59 184 SUPERFAMILY SSF55811 6 176 1.18E-45 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 Pfam PF13541 Subunit ChlI of Mg-chelatase 361 425 5.2E-8 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 PRINTS PR01874 DNA repair protein radA signature 209 237 3.8E-87 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 PRINTS PR01874 DNA repair protein radA signature 79 107 3.8E-87 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 PRINTS PR01874 DNA repair protein radA signature 120 137 3.8E-87 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 PRINTS PR01874 DNA repair protein radA signature 170 194 3.8E-87 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 PRINTS PR01874 DNA repair protein radA signature 244 270 3.8E-87 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 PRINTS PR01874 DNA repair protein radA signature 10 34 3.8E-87 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 PRINTS PR01874 DNA repair protein radA signature 318 341 3.8E-87 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 448 1.9E-189 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 Pfam PF13481 AAA domain 79 218 2.6E-13 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 SMART SM00382 87 240 1.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 SUPERFAMILY SSF52540 69 287 3.04E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 Gene3D G3DSA:3.40.50.300 38 246 1.1E-18 T 29-03-2018 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 Gene3D G3DSA:3.30.230.10 247 454 8.3E-44 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 Hamap MF_01498 DNA repair protein RadA [radA]. 21 452 43.53 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 SUPERFAMILY SSF54211 299 452 4.93E-39 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS00970 381cfa1f7ffae4c272d1669b0644cd11 454 SUPERFAMILY SSF54211 251 265 4.93E-39 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 449 461 1.1E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 424 441 1.1E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 314 328 1.1E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 403 414 1.1E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 382 390 1.1E-15 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 SUPERFAMILY SSF51445 70 483 4.83E-163 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 SUPERFAMILY SSF51445 3 41 4.83E-163 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 Gene3D G3DSA:3.20.20.80 2 487 1.0E-153 T 29-03-2018 SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 Pfam PF00232 Glycosyl hydrolase family 1 3 483 9.7E-141 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06200 45f25c0bf5f948ef87a3dd4777e11177 488 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 382 390 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site SPSF3K_RS03175 2cd10dcf8165136006bde4b15a1cd3e0 238 Gene3D G3DSA:3.30.70.980 80 174 7.6E-26 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SPSF3K_RS03175 2cd10dcf8165136006bde4b15a1cd3e0 238 Gene3D G3DSA:3.30.70.980 181 236 1.0E-8 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SPSF3K_RS03175 2cd10dcf8165136006bde4b15a1cd3e0 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 30.59 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SPSF3K_RS03175 2cd10dcf8165136006bde4b15a1cd3e0 238 Gene3D G3DSA:1.10.10.200 2 76 4.1E-24 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like SPSF3K_RS03175 2cd10dcf8165136006bde4b15a1cd3e0 238 SUPERFAMILY SSF75625 1 235 4.58E-79 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SPSF3K_RS03175 2cd10dcf8165136006bde4b15a1cd3e0 238 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 2.2E-69 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SPSF3K_RS03175 2cd10dcf8165136006bde4b15a1cd3e0 238 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 62.051 T 29-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN SPSF3K_RS03175 2cd10dcf8165136006bde4b15a1cd3e0 238 Pfam PF01709 Transcriptional regulator 4 235 2.0E-80 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 Hamap MF_00303 Trigger factor [tig]. 1 427 22.636 T 29-03-2018 IPR005215 Trigger factor GO:0015031 SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 SUPERFAMILY SSF109998 250 427 5.23E-41 T 29-03-2018 IPR027304 Trigger factor/SurA domain SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 PIRSF PIRSF003095 1 427 3.5E-123 T 29-03-2018 IPR005215 Trigger factor GO:0015031 SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 421 4.5E-47 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 Gene3D G3DSA:3.30.70.1050 1 119 5.1E-32 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 SUPERFAMILY SSF54534 89 243 6.09E-36 T 29-03-2018 SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 2.5E-38 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 TIGRFAM TIGR00115 tig: trigger factor 13 420 2.8E-129 T 29-03-2018 IPR005215 Trigger factor GO:0015031 SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 Gene3D G3DSA:1.10.3120.10 213 401 4.6E-51 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 231 3.4E-15 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain SPSF3K_RS02905 8d98403b53a47777f78ffbd270b53ffc 427 SUPERFAMILY SSF102735 1 128 5.36E-34 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SPSF3K_RS00220 193e9baf7c5070947b9ec95a4e9370dc 111 Pfam PF13192 Thioredoxin domain 35 107 5.8E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS00220 193e9baf7c5070947b9ec95a4e9370dc 111 SUPERFAMILY SSF52833 36 107 3.22E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS00220 193e9baf7c5070947b9ec95a4e9370dc 111 Gene3D G3DSA:3.40.30.10 20 111 1.2E-7 T 29-03-2018 SPSF3K_RS00220 193e9baf7c5070947b9ec95a4e9370dc 111 PIRSF PIRSF037031 33 109 5.8E-28 T 29-03-2018 IPR005243 Redox-active disulphide protein 2 SPSF3K_RS05180 647fc521d832bc505c968745147fdf72 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 5.4E-35 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05180 647fc521d832bc505c968745147fdf72 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 6.8E-37 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05180 647fc521d832bc505c968745147fdf72 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 104 25.364 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05180 647fc521d832bc505c968745147fdf72 104 SUPERFAMILY SSF141091 4 103 4.58E-36 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05180 647fc521d832bc505c968745147fdf72 104 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00955 18c52e683f6a4207454879a610c20724 200 SUPERFAMILY SSF52218 1 176 5.79E-39 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS00955 18c52e683f6a4207454879a610c20724 200 Pfam PF03358 NADPH-dependent FMN reductase 1 145 1.8E-33 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SPSF3K_RS00955 18c52e683f6a4207454879a610c20724 200 Gene3D G3DSA:3.40.50.360 1 195 8.1E-30 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 52 2.6E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 Gene3D G3DSA:1.10.260.40 20 58 1.5E-20 T 29-03-2018 SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 SUPERFAMILY SSF53822 63 321 1.2E-42 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 Gene3D G3DSA:1.10.10.10 1 19 4.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 Pfam PF13377 Periplasmic binding protein-like domain 175 334 1.2E-18 T 29-03-2018 SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 SMART SM00354 4 75 2.7E-32 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 Gene3D G3DSA:3.40.50.2300 59 179 3.0E-22 T 29-03-2018 SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 SUPERFAMILY SSF47413 3 63 6.52E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 Gene3D G3DSA:3.40.50.2300 180 318 1.8E-22 T 29-03-2018 SPSF3K_RS01305 9c6cad9da7061bfce04f67e5b1fbb642 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 29-03-2018 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Pfam PF00391 PEP-utilising enzyme, mobile domain 422 503 7.3E-26 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 SUPERFAMILY SSF56059 2 379 4.0E-143 T 29-03-2018 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 296 7.8E-46 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 304 356 6.6E-11 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Gene3D G3DSA:1.10.189.10 342 390 6.1E-22 T 29-03-2018 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 4 870 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 SUPERFAMILY SSF51621 512 870 1.08E-124 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 SUPERFAMILY SSF52009 390 512 6.15E-37 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 PIRSF PIRSF000853 2 877 0.0 T 29-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Gene3D G3DSA:3.30.470.20 244 341 3.1E-23 T 29-03-2018 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Gene3D G3DSA:3.50.30.10 392 533 3.4E-39 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Gene3D G3DSA:1.20.80.30 118 198 4.8E-34 T 29-03-2018 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Gene3D G3DSA:3.30.1490.20 3 117 8.1E-32 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 450 461 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Gene3D G3DSA:3.20.20.60 534 873 2.2E-110 T 29-03-2018 SPSF3K_RS10210 31a90ad26d55ee2a449517d698ee6111 881 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 519 869 3.8E-88 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SPSF3K_RS03235 8ec1be3783d576cd847cb50d4b53d476 228 SUPERFAMILY SSF46894 128 226 8.22E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPSF3K_RS03235 8ec1be3783d576cd847cb50d4b53d476 228 Pfam PF00072 Response regulator receiver domain 5 114 8.3E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS03235 8ec1be3783d576cd847cb50d4b53d476 228 SUPERFAMILY SSF52172 2 131 2.13E-40 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS03235 8ec1be3783d576cd847cb50d4b53d476 228 Gene3D G3DSA:3.40.50.2300 1 147 3.2E-35 T 29-03-2018 SPSF3K_RS03235 8ec1be3783d576cd847cb50d4b53d476 228 SMART SM00448 3 113 4.0E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS03235 8ec1be3783d576cd847cb50d4b53d476 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 224 1.3E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS03235 8ec1be3783d576cd847cb50d4b53d476 228 Gene3D G3DSA:1.10.10.10 148 228 2.4E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03235 8ec1be3783d576cd847cb50d4b53d476 228 SMART SM00862 150 225 1.8E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 Pfam PF00232 Glycosyl hydrolase family 1 3 463 4.2E-156 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 Gene3D G3DSA:3.20.20.80 1 466 3.2E-145 T 29-03-2018 SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 TIGRFAM TIGR01233 lacG: 6-phospho-beta-galactosidase 3 466 2.5E-221 T 29-03-2018 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85 SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 SUPERFAMILY SSF51445 1 464 5.82E-160 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 6.0E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 434 446 6.0E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 6.0E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 6.0E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS05985 bffa54ed97eafc7b3f96a8d6f8f7ae48 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 6.0E-22 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS00875 3d5bfa840766cfcbffe9cbfe89b4a5e1 183 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 4 170 5.0E-78 T 29-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 SPSF3K_RS00875 3d5bfa840766cfcbffe9cbfe89b4a5e1 183 PIRSF PIRSF038321 1 181 2.2E-89 T 29-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 SPSF3K_RS00875 3d5bfa840766cfcbffe9cbfe89b4a5e1 183 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 1 179 1.6E-82 T 29-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 SPSF3K_RS04350 8568259f596a4b5ef851cba137a47c19 204 Gene3D G3DSA:2.60.120.10 9 115 3.5E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS04350 8568259f596a4b5ef851cba137a47c19 204 SUPERFAMILY SSF51182 3 172 7.65E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain SPSF3K_RS04350 8568259f596a4b5ef851cba137a47c19 204 Pfam PF05962 HutD 10 169 9.1E-20 T 29-03-2018 IPR010282 Uncharacterised protein family HutD/Ves SPSF3K_RS02990 e63e9691c56059b6a7aa4eaf64894d45 246 Pfam PF00005 ABC transporter 21 170 8.8E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS02990 e63e9691c56059b6a7aa4eaf64894d45 246 SUPERFAMILY SSF52540 5 240 2.28E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02990 e63e9691c56059b6a7aa4eaf64894d45 246 Gene3D G3DSA:3.40.50.300 2 245 2.3E-74 T 29-03-2018 SPSF3K_RS02990 e63e9691c56059b6a7aa4eaf64894d45 246 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS02990 e63e9691c56059b6a7aa4eaf64894d45 246 SMART SM00382 30 218 2.3E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02990 e63e9691c56059b6a7aa4eaf64894d45 246 PIRSF PIRSF039085 2 246 2.6E-108 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SPSF3K_RS06190 086675e789517c2fec13904c1dc626eb 204 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 46 195 6.0E-21 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SPSF3K_RS06190 086675e789517c2fec13904c1dc626eb 204 SUPERFAMILY SSF52266 25 204 2.33E-42 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SPSF3K_RS06190 086675e789517c2fec13904c1dc626eb 204 Gene3D G3DSA:3.40.50.1110 11 203 5.6E-29 T 29-03-2018 SPSF3K_RS05960 04df64429d4a7ca2a523d14cdfd92a16 142 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 140 9.3E-36 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS05960 04df64429d4a7ca2a523d14cdfd92a16 142 Gene3D G3DSA:3.40.1400.10 1 142 4.4E-42 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS05960 04df64429d4a7ca2a523d14cdfd92a16 142 TIGRFAM TIGR01118 lacA: galactose-6-phosphate isomerase, LacA subunit 1 141 2.2E-75 T 29-03-2018 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26 SPSF3K_RS05960 04df64429d4a7ca2a523d14cdfd92a16 142 Hamap MF_01555 Galactose-6-phosphate isomerase subunit LacA [lacA]. 1 142 40.185 T 29-03-2018 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26 SPSF3K_RS05960 04df64429d4a7ca2a523d14cdfd92a16 142 PIRSF PIRSF005384 1 142 3.9E-42 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS05960 04df64429d4a7ca2a523d14cdfd92a16 142 Pfam PF02502 Ribose/Galactose Isomerase 3 138 1.2E-39 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS05960 04df64429d4a7ca2a523d14cdfd92a16 142 SUPERFAMILY SSF89623 1 141 2.09E-45 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS01280 804cf67b488e733660ba1ccd6cb6f3e5 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 23.277 T 29-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid SPSF3K_RS01280 804cf67b488e733660ba1ccd6cb6f3e5 89 SUPERFAMILY SSF57716 2 89 5.63E-27 T 29-03-2018 SPSF3K_RS01280 804cf67b488e733660ba1ccd6cb6f3e5 89 Gene3D G3DSA:4.10.830.10 1 89 1.0E-30 T 29-03-2018 SPSF3K_RS01280 804cf67b488e733660ba1ccd6cb6f3e5 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 8.7E-25 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS07815 a51339c8baef883d8d6491fa76d2e5f5 457 Gene3D G3DSA:3.40.309.10 245 438 2.7E-59 T 29-03-2018 SPSF3K_RS07815 a51339c8baef883d8d6491fa76d2e5f5 457 SUPERFAMILY SSF53720 4 453 3.8E-126 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS07815 a51339c8baef883d8d6491fa76d2e5f5 457 Pfam PF00171 Aldehyde dehydrogenase family 3 448 1.7E-118 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS07815 a51339c8baef883d8d6491fa76d2e5f5 457 Gene3D G3DSA:3.40.605.10 2 244 1.3E-56 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 SUPERFAMILY SSF53335 146 438 4.34E-65 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 321 332 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 435 7.1E-52 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 SUPERFAMILY SSF48013 6 133 2.75E-30 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 239 2.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 264 2.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 421 438 2.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 322 334 2.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 372 388 2.4E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 Pfam PF01029 NusB family 9 128 3.5E-25 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 Gene3D G3DSA:3.40.50.150 234 439 4.8E-52 T 29-03-2018 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 13 437 3.9E-107 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS09650 39c60db5bdf46e0d825dc4c7802e4f89 440 Gene3D G3DSA:1.10.940.10 5 150 9.2E-25 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPSF3K_RS10860 bc5eadafc98a2bfcf8a59c6c6a1fd3ab 427 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 194 2.7E-53 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SPSF3K_RS10860 bc5eadafc98a2bfcf8a59c6c6a1fd3ab 427 Pfam PF01171 PP-loop family 22 191 6.5E-54 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 SPSF3K_RS10860 bc5eadafc98a2bfcf8a59c6c6a1fd3ab 427 SMART SM00977 349 418 1.9E-5 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SPSF3K_RS10860 bc5eadafc98a2bfcf8a59c6c6a1fd3ab 427 Gene3D G3DSA:3.40.50.620 2 235 8.5E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS10860 bc5eadafc98a2bfcf8a59c6c6a1fd3ab 427 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 349 392 6.8E-8 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SPSF3K_RS10860 bc5eadafc98a2bfcf8a59c6c6a1fd3ab 427 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 3 290 21.906 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SPSF3K_RS10860 bc5eadafc98a2bfcf8a59c6c6a1fd3ab 427 SUPERFAMILY SSF52402 9 212 4.19E-51 T 29-03-2018 SPSF3K_RS08375 9a74bf497e294539ea5763f4802e5413 331 Pfam PF01381 Helix-turn-helix 8 61 5.7E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS08375 9a74bf497e294539ea5763f4802e5413 331 Gene3D G3DSA:3.30.1190.10 26 105 5.0E-18 T 29-03-2018 SPSF3K_RS08375 9a74bf497e294539ea5763f4802e5413 331 Gene3D G3DSA:1.10.10.10 2 25 0.0032 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08375 9a74bf497e294539ea5763f4802e5413 331 SUPERFAMILY SSF47413 1 65 5.89E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS08375 9a74bf497e294539ea5763f4802e5413 331 Gene3D G3DSA:1.20.1250.20 106 328 4.6E-4 T 29-03-2018 SPSF3K_RS08375 9a74bf497e294539ea5763f4802e5413 331 SMART SM00530 6 61 1.0E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS09985 7fa8fa15356a64595e27c2c4363e5f77 241 Gene3D G3DSA:3.40.50.300 1 234 1.2E-59 T 29-03-2018 SPSF3K_RS09985 7fa8fa15356a64595e27c2c4363e5f77 241 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS09985 7fa8fa15356a64595e27c2c4363e5f77 241 SUPERFAMILY SSF52540 2 223 1.05E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09985 7fa8fa15356a64595e27c2c4363e5f77 241 SMART SM00382 26 211 1.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS09985 7fa8fa15356a64595e27c2c4363e5f77 241 Pfam PF00005 ABC transporter 17 160 1.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS03040 9b338786a9b9ac4c4db79af92ad8b47b 472 SUPERFAMILY SSF101960 40 469 6.67E-139 T 29-03-2018 SPSF3K_RS03040 9b338786a9b9ac4c4db79af92ad8b47b 472 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 463 2.2E-222 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 SPSF3K_RS03040 9b338786a9b9ac4c4db79af92ad8b47b 472 Pfam PF01458 Uncharacterized protein family (UPF0051) 218 443 2.2E-76 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Pfam PF00364 Biotin-requiring enzyme 15 71 3.0E-10 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PIRSF PIRSF000350 31 553 8.3E-94 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Gene3D G3DSA:3.50.50.60 208 340 3.3E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 149 4.9E-65 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 410 4.9E-65 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 359 373 4.9E-65 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 459 4.9E-65 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 502 517 4.9E-65 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 102 124 4.9E-65 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 524 544 4.9E-65 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 243 4.9E-65 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 295 4.9E-65 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Gene3D G3DSA:2.40.50.100 12 57 5.1E-9 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 102 423 6.9E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Gene3D G3DSA:3.40.50.720 113 145 0.035 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 SUPERFAMILY SSF51230 14 82 3.14E-12 T 29-03-2018 IPR011053 Single hybrid motif SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 288 3.9E-34 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 358 374 3.9E-34 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 388 410 3.9E-34 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 249 3.9E-34 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 122 3.9E-34 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 SUPERFAMILY SSF51905 95 468 9.97E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Gene3D G3DSA:1.10.287.990 146 201 2.0E-21 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 135 145 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Gene3D G3DSA:3.50.50.60 341 452 2.0E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Gene3D G3DSA:2.40.50.100 58 112 1.8E-4 T 29-03-2018 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 23 52 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 SUPERFAMILY SSF55424 441 552 5.84E-33 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 442 549 8.3E-29 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 Gene3D G3DSA:3.30.390.30 453 560 1.8E-32 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS06895 10a25f97e5ce5598bf1cd74b089b6b73 560 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 101 552 3.4E-155 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 SPSF3K_RS10630 b34e2eacfff6dce01d51778cc13a7493 235 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10630 b34e2eacfff6dce01d51778cc13a7493 235 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 3 233 32.38 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10630 b34e2eacfff6dce01d51778cc13a7493 235 Gene3D G3DSA:3.30.200.20 1 92 1.0E-26 T 29-03-2018 SPSF3K_RS10630 b34e2eacfff6dce01d51778cc13a7493 235 Gene3D G3DSA:3.30.470.20 93 219 8.5E-47 T 29-03-2018 SPSF3K_RS10630 b34e2eacfff6dce01d51778cc13a7493 235 ProSitePatterns PS01058 SAICAR synthetase signature 2. 172 180 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10630 b34e2eacfff6dce01d51778cc13a7493 235 SUPERFAMILY SSF56104 12 232 3.6E-78 T 29-03-2018 SPSF3K_RS10630 b34e2eacfff6dce01d51778cc13a7493 235 Pfam PF01259 SAICAR synthetase 6 227 2.7E-61 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10630 b34e2eacfff6dce01d51778cc13a7493 235 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 204 1.1E-70 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 Gene3D G3DSA:3.30.70.890 171 292 2.9E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 PRINTS PR00959 Mevalonate kinase family signature 10 34 1.2E-18 T 29-03-2018 SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 PRINTS PR00959 Mevalonate kinase family signature 81 103 1.2E-18 T 29-03-2018 SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 PRINTS PR00959 Mevalonate kinase family signature 250 267 1.2E-18 T 29-03-2018 SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 10 265 8.4E-74 T 29-03-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 SUPERFAMILY SSF55060 159 290 2.7E-30 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 Pfam PF00288 GHMP kinases N terminal domain 77 140 2.3E-11 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 SUPERFAMILY SSF54211 8 175 7.59E-32 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 Pfam PF08544 GHMP kinases C terminal 204 283 5.4E-14 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 Gene3D G3DSA:3.30.230.10 1 61 4.2E-7 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS05405 2fa1f7968183c7c94a0a3b40d84566f2 292 Gene3D G3DSA:3.30.230.10 62 170 7.2E-21 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 5 742 0.0 T 29-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Gene3D G3DSA:1.10.268.10 340 482 5.0E-42 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 SUPERFAMILY SSF101904 496 816 2.09E-66 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Gene3D G3DSA:3.90.199.10 30 209 2.7E-75 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 SMART SM00434 7 460 2.7E-251 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Gene3D G3DSA:2.120.10.90 494 818 9.8E-62 T 29-03-2018 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Gene3D G3DSA:3.30.1360.40 232 328 8.8E-33 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 467 2.4E-147 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 702 731 0.0031 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 546 597 7.6E-4 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 607 649 0.41 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 654 699 1.2E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 3 819 33.285 T 29-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS07595 fb4c4770268154b560c24947450d3e74 819 SUPERFAMILY SSF56719 27 482 7.85E-164 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SPSF3K_RS03170 42b2678055729d561a495c48fe57a5f7 278 Gene3D G3DSA:3.90.25.10 140 262 1.9E-4 T 29-03-2018 SPSF3K_RS03170 42b2678055729d561a495c48fe57a5f7 278 Pfam PF05368 NmrA-like family 5 217 4.4E-22 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 SPSF3K_RS03170 42b2678055729d561a495c48fe57a5f7 278 Gene3D G3DSA:3.40.50.720 1 139 5.5E-15 T 29-03-2018 SPSF3K_RS03170 42b2678055729d561a495c48fe57a5f7 278 SUPERFAMILY SSF51735 3 233 7.54E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS08290 bf66ccf0b3d87ab88589bf90af86665e 503 SUPERFAMILY SSF52540 322 482 3.05E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08290 bf66ccf0b3d87ab88589bf90af86665e 503 SUPERFAMILY SSF52540 6 199 1.61E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08290 bf66ccf0b3d87ab88589bf90af86665e 503 Pfam PF00005 ABC transporter 333 449 1.9E-13 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08290 bf66ccf0b3d87ab88589bf90af86665e 503 Pfam PF00005 ABC transporter 20 158 1.4E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08290 bf66ccf0b3d87ab88589bf90af86665e 503 Gene3D G3DSA:3.40.50.300 1 265 3.0E-35 T 29-03-2018 SPSF3K_RS08290 bf66ccf0b3d87ab88589bf90af86665e 503 ProSitePatterns PS00211 ABC transporters family signature. 422 436 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS08290 bf66ccf0b3d87ab88589bf90af86665e 503 SMART SM00382 339 502 5.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08290 bf66ccf0b3d87ab88589bf90af86665e 503 SMART SM00382 28 203 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08290 bf66ccf0b3d87ab88589bf90af86665e 503 Gene3D G3DSA:3.40.50.300 266 500 4.4E-26 T 29-03-2018 SPSF3K_RS08410 5c6253025a54ada1e4c383cadfd026db 308 SUPERFAMILY SSF51430 1 300 7.6E-74 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS08410 5c6253025a54ada1e4c383cadfd026db 308 Gene3D G3DSA:3.20.20.100 1 306 2.9E-72 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS08410 5c6253025a54ada1e4c383cadfd026db 308 Pfam PF00248 Aldo/keto reductase family 16 298 1.3E-56 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS08410 5c6253025a54ada1e4c383cadfd026db 308 PRINTS PR00069 Aldo-keto reductase signature 188 217 1.2E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS08410 5c6253025a54ada1e4c383cadfd026db 308 PRINTS PR00069 Aldo-keto reductase signature 236 260 1.2E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS08410 5c6253025a54ada1e4c383cadfd026db 308 PRINTS PR00069 Aldo-keto reductase signature 103 121 1.2E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS08410 5c6253025a54ada1e4c383cadfd026db 308 PRINTS PR00069 Aldo-keto reductase signature 38 62 1.2E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 SUPERFAMILY SSF52540 4 161 1.66E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 Hamap MF_00109 Shikimate kinase [aroK]. 1 161 23.188 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 PRINTS PR01100 Shikimate kinase family signature 23 36 5.1E-19 T 29-03-2018 SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 PRINTS PR01100 Shikimate kinase family signature 51 59 5.1E-19 T 29-03-2018 SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 PRINTS PR01100 Shikimate kinase family signature 70 79 5.1E-19 T 29-03-2018 SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 PRINTS PR01100 Shikimate kinase family signature 3 18 5.1E-19 T 29-03-2018 SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 PRINTS PR01100 Shikimate kinase family signature 92 109 5.1E-19 T 29-03-2018 SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 Pfam PF01202 Shikimate kinase 9 160 6.3E-38 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 Gene3D G3DSA:3.40.50.300 4 163 6.0E-22 T 29-03-2018 SPSF3K_RS08445 1714b10f080a3f3c02f139d8073321e1 163 ProSitePatterns PS01128 Shikimate kinase signature. 52 78 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 SPSF3K_RS10975 7fc1c18085e586b5ff10304f9d9b4f54 228 SUPERFAMILY SSF53098 71 187 1.11E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS10975 7fc1c18085e586b5ff10304f9d9b4f54 228 Pfam PF13610 DDE domain 74 204 8.3E-41 T 29-03-2018 IPR032874 DDE domain SPSF3K_RS10975 7fc1c18085e586b5ff10304f9d9b4f54 228 Gene3D G3DSA:1.10.10.10 6 65 3.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10975 7fc1c18085e586b5ff10304f9d9b4f54 228 Gene3D G3DSA:3.30.420.10 66 208 2.2E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS11055 7fc1c18085e586b5ff10304f9d9b4f54 228 SUPERFAMILY SSF53098 71 187 1.11E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS11055 7fc1c18085e586b5ff10304f9d9b4f54 228 Pfam PF13610 DDE domain 74 204 8.3E-41 T 29-03-2018 IPR032874 DDE domain SPSF3K_RS11055 7fc1c18085e586b5ff10304f9d9b4f54 228 Gene3D G3DSA:1.10.10.10 6 65 3.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS11055 7fc1c18085e586b5ff10304f9d9b4f54 228 Gene3D G3DSA:3.30.420.10 66 208 2.2E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 PIRSF PIRSF006356 1 411 7.3E-172 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 Pfam PF02274 Amidinotransferase 21 408 4.0E-113 T 29-03-2018 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 Gene3D G3DSA:3.75.10.10 6 409 8.5E-100 T 29-03-2018 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 SUPERFAMILY SSF55909 4 411 5.53E-134 T 29-03-2018 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 PRINTS PR01466 Bacterial arginine deiminase signature 185 200 6.6E-59 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 PRINTS PR01466 Bacterial arginine deiminase signature 390 408 6.6E-59 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 PRINTS PR01466 Bacterial arginine deiminase signature 5 25 6.6E-59 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 PRINTS PR01466 Bacterial arginine deiminase signature 157 175 6.6E-59 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 PRINTS PR01466 Bacterial arginine deiminase signature 347 364 6.6E-59 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 PRINTS PR01466 Bacterial arginine deiminase signature 367 381 6.6E-59 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 Hamap MF_00242 Arginine deiminase [arcA]. 4 411 46.544 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SPSF3K_RS09080 47f1ef8e95b87c183d3e2d4dc88c2cbc 411 TIGRFAM TIGR01078 arcA: arginine deiminase 7 410 2.4E-184 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 Gene3D G3DSA:3.40.50.720 3 49 6.3E-9 T 29-03-2018 SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 Gene3D G3DSA:3.40.50.720 50 262 1.1E-57 T 29-03-2018 SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 SUPERFAMILY SSF51735 9 255 1.53E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.6E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 252 1.1E-57 T 29-03-2018 SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 5.5E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 5.5E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS09350 cf31a9365554024dcc6379554e3c4bb3 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.5E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS05350 f718dd648120186d16fe323abfcb4f74 282 SUPERFAMILY SSF82549 1 281 2.43E-75 T 29-03-2018 SPSF3K_RS05350 f718dd648120186d16fe323abfcb4f74 282 Gene3D G3DSA:3.30.1180.10 154 279 2.7E-33 T 29-03-2018 SPSF3K_RS05350 f718dd648120186d16fe323abfcb4f74 282 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 7.3E-79 T 29-03-2018 IPR003797 DegV SPSF3K_RS05350 f718dd648120186d16fe323abfcb4f74 282 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 280 8.5E-74 T 29-03-2018 IPR003797 DegV SPSF3K_RS05350 f718dd648120186d16fe323abfcb4f74 282 Gene3D G3DSA:2.20.28.50 29 53 5.6E-16 T 29-03-2018 SPSF3K_RS05350 f718dd648120186d16fe323abfcb4f74 282 Gene3D G3DSA:3.40.50.10440 54 150 2.7E-17 T 29-03-2018 SPSF3K_RS04225 5a8afc91c1f1dbc5f01957e6064e40b1 287 Gene3D G3DSA:1.10.3720.10 1 278 1.9E-34 T 29-03-2018 SPSF3K_RS04225 5a8afc91c1f1dbc5f01957e6064e40b1 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 277 3.7E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04225 5a8afc91c1f1dbc5f01957e6064e40b1 287 SUPERFAMILY SSF161098 13 279 7.76E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04225 5a8afc91c1f1dbc5f01957e6064e40b1 287 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 8 281 1.3E-81 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 SMART SM00363 352 414 1.4E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 Pfam PF00579 tRNA synthetases class I (W and Y) 29 322 1.9E-83 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 Gene3D G3DSA:1.10.240.10 222 315 5.6E-34 T 29-03-2018 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 417 1.8E-128 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 Gene3D G3DSA:3.40.50.620 1 221 3.2E-67 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 3.0E-27 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 3.0E-27 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 3.0E-27 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 3.0E-27 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 Gene3D G3DSA:3.10.290.10 316 418 9.8E-23 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 44.217 T 29-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 Pfam PF01479 S4 domain 357 399 3.2E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 SUPERFAMILY SSF55174 321 417 5.36E-24 T 29-03-2018 SPSF3K_RS01910 98cb6de9201b6ea41f04d97b7a43b2b0 418 SUPERFAMILY SSF52374 1 322 5.35E-106 T 29-03-2018 SPSF3K_RS03205 1688fc2abe140659eb0a8c69924d6e5b 224 SUPERFAMILY SSF51735 6 135 1.08E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS03205 1688fc2abe140659eb0a8c69924d6e5b 224 SUPERFAMILY SSF116726 134 217 6.67E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPSF3K_RS03205 1688fc2abe140659eb0a8c69924d6e5b 224 Gene3D G3DSA:3.40.50.720 1 139 1.7E-21 T 29-03-2018 SPSF3K_RS03205 1688fc2abe140659eb0a8c69924d6e5b 224 Gene3D G3DSA:3.30.70.1450 140 218 8.2E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPSF3K_RS03205 1688fc2abe140659eb0a8c69924d6e5b 224 Pfam PF02254 TrkA-N domain 9 122 4.0E-25 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SPSF3K_RS00840 eb09d02f930ce5308925436007c6b03b 169 Pfam PF14437 MafB19-like deaminase 7 153 7.1E-37 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 SPSF3K_RS00840 eb09d02f930ce5308925436007c6b03b 169 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 94 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SPSF3K_RS00840 eb09d02f930ce5308925436007c6b03b 169 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 12 153 44.904 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 SPSF3K_RS00840 eb09d02f930ce5308925436007c6b03b 169 Gene3D G3DSA:3.40.140.10 1 163 5.9E-52 T 29-03-2018 SPSF3K_RS00840 eb09d02f930ce5308925436007c6b03b 169 SUPERFAMILY SSF53927 5 157 5.69E-51 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SPSF3K_RS07080 cda50be711d2df259d7ae85e7a106449 288 Gene3D G3DSA:3.40.190.10 31 162 1.3E-31 T 29-03-2018 SPSF3K_RS07080 cda50be711d2df259d7ae85e7a106449 288 Gene3D G3DSA:3.40.190.10 171 288 1.2E-13 T 29-03-2018 SPSF3K_RS07080 cda50be711d2df259d7ae85e7a106449 288 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 5 272 1.1E-82 T 29-03-2018 IPR011862 Phosphate binding protein GO:0006810 SPSF3K_RS07080 cda50be711d2df259d7ae85e7a106449 288 SUPERFAMILY SSF53850 33 277 2.0E-71 T 29-03-2018 SPSF3K_RS07080 cda50be711d2df259d7ae85e7a106449 288 Pfam PF12849 PBP superfamily domain 31 258 7.2E-36 T 29-03-2018 IPR024370 PBP domain SPSF3K_RS03250 7108b2bce95718122df54b7fc8b4ed74 394 Gene3D G3DSA:1.10.10.630 250 331 1.4E-4 T 29-03-2018 IPR034829 DnaD-like domain SPSF3K_RS03250 7108b2bce95718122df54b7fc8b4ed74 394 Pfam PF07261 Replication initiation and membrane attachment 260 330 2.4E-6 T 29-03-2018 IPR006343 DnaD domain SPSF3K_RS00350 5f07cc003c9a2cb018dc718f628806b9 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 1.0E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00350 5f07cc003c9a2cb018dc718f628806b9 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.0E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00350 5f07cc003c9a2cb018dc718f628806b9 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 1.0E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00350 5f07cc003c9a2cb018dc718f628806b9 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 1.0E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00350 5f07cc003c9a2cb018dc718f628806b9 109 SUPERFAMILY SSF46785 23 108 1.84E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00350 5f07cc003c9a2cb018dc718f628806b9 109 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS00350 5f07cc003c9a2cb018dc718f628806b9 109 Gene3D G3DSA:1.10.10.10 1 109 1.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00350 5f07cc003c9a2cb018dc718f628806b9 109 Pfam PF01022 Bacterial regulatory protein, arsR family 41 86 3.8E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00350 5f07cc003c9a2cb018dc718f628806b9 109 SMART SM00418 34 109 2.3E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00945 032e46b7681269c8d65e3c35130253ec 594 SUPERFAMILY SSF90123 5 342 1.96E-62 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS00945 032e46b7681269c8d65e3c35130253ec 594 Gene3D G3DSA:1.20.1560.10 1 344 3.3E-61 T 29-03-2018 SPSF3K_RS00945 032e46b7681269c8d65e3c35130253ec 594 SUPERFAMILY SSF52540 345 591 4.65E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00945 032e46b7681269c8d65e3c35130253ec 594 Pfam PF00664 ABC transporter transmembrane region 19 304 1.5E-39 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS00945 032e46b7681269c8d65e3c35130253ec 594 SMART SM00382 380 566 3.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00945 032e46b7681269c8d65e3c35130253ec 594 Gene3D G3DSA:3.40.50.300 345 592 2.0E-70 T 29-03-2018 SPSF3K_RS00945 032e46b7681269c8d65e3c35130253ec 594 Pfam PF00005 ABC transporter 371 520 3.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS04590 66c30d732190bdaf5240a3b2d28ed859 318 Pfam PF00294 pfkB family carbohydrate kinase 19 300 5.3E-50 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SPSF3K_RS04590 66c30d732190bdaf5240a3b2d28ed859 318 Gene3D G3DSA:2.20.150.10 17 49 2.9E-13 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain SPSF3K_RS04590 66c30d732190bdaf5240a3b2d28ed859 318 TIGRFAM TIGR01231 lacC: tagatose-6-phosphate kinase 9 318 1.5E-148 T 29-03-2018 IPR005926 Tagatose-6-phosphate kinase GO:0009024|GO:0019512 KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 SPSF3K_RS04590 66c30d732190bdaf5240a3b2d28ed859 318 PIRSF PIRSF000535 7 318 9.5E-125 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPSF3K_RS04590 66c30d732190bdaf5240a3b2d28ed859 318 SUPERFAMILY SSF53613 9 296 4.68E-61 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS04590 66c30d732190bdaf5240a3b2d28ed859 318 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SPSF3K_RS04590 66c30d732190bdaf5240a3b2d28ed859 318 Gene3D G3DSA:3.40.1190.20 50 318 1.2E-36 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS04590 66c30d732190bdaf5240a3b2d28ed859 318 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 10 316 5.1E-93 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 Pfam PF03949 Malic enzyme, NAD binding domain 164 367 1.8E-23 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 SUPERFAMILY SSF53223 14 160 1.44E-54 T 29-03-2018 SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 SMART SM01274 17 150 2.5E-81 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 Gene3D G3DSA:3.40.50.720 160 386 1.2E-68 T 29-03-2018 SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 SUPERFAMILY SSF51735 162 384 4.37E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 SMART SM00919 162 386 6.7E-106 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 Pfam PF00390 Malic enzyme, N-terminal domain 19 149 6.1E-30 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 PIRSF PIRSF000106 21 386 2.1E-80 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 ProSitePatterns PS00331 Malic enzymes signature. 158 174 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 SPSF3K_RS06155 45477c59e2fdf563e267eb0e0f020207 386 Gene3D G3DSA:3.40.50.10380 6 159 2.9E-39 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SPSF3K_RS04470 61ae307d2790c0b76aedbe8d816ec3a4 116 Pfam PF01545 Cation efflux family 13 106 4.3E-19 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPSF3K_RS04470 61ae307d2790c0b76aedbe8d816ec3a4 116 SUPERFAMILY SSF161111 9 108 3.92E-22 T 29-03-2018 SPSF3K_RS04470 61ae307d2790c0b76aedbe8d816ec3a4 116 Gene3D G3DSA:1.20.1510.10 10 115 1.3E-17 T 29-03-2018 SPSF3K_RS08520 33175c8c85aeb5a467f8d7ec32abff30 360 Pfam PF00270 DEAD/DEAH box helicase 22 181 9.2E-39 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPSF3K_RS08520 33175c8c85aeb5a467f8d7ec32abff30 360 Gene3D G3DSA:3.40.50.300 207 360 1.7E-32 T 29-03-2018 SPSF3K_RS08520 33175c8c85aeb5a467f8d7ec32abff30 360 SUPERFAMILY SSF52540 66 337 9.0E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08520 33175c8c85aeb5a467f8d7ec32abff30 360 Pfam PF00271 Helicase conserved C-terminal domain 227 323 9.6E-20 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS08520 33175c8c85aeb5a467f8d7ec32abff30 360 Gene3D G3DSA:3.40.50.300 4 206 9.0E-44 T 29-03-2018 SPSF3K_RS08520 33175c8c85aeb5a467f8d7ec32abff30 360 SMART SM00490 242 323 2.5E-18 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS08520 33175c8c85aeb5a467f8d7ec32abff30 360 SMART SM00487 17 207 1.0E-41 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 SUPERFAMILY SSF116878 383 458 5.62E-48 T 29-03-2018 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 SUPERFAMILY SSF116878 129 228 5.62E-48 T 29-03-2018 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 Gene3D G3DSA:1.20.120.430 291 458 1.5E-29 T 29-03-2018 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 Pfam PF10396 GTP-binding protein TrmE N-terminus 9 127 1.2E-41 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 Pfam PF12631 MnmE helical domain 130 455 9.8E-57 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 8 458 34.067 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 SUPERFAMILY SSF52540 205 373 8.5E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 SUPERFAMILY SSF52540 82 170 8.5E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 Gene3D G3DSA:1.20.120.430 129 290 2.5E-30 T 29-03-2018 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 Pfam PF01926 50S ribosome-binding GTPase 228 339 3.7E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 15 458 7.7E-132 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 228 369 6.7E-26 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS07785 a9d7eb53f7223f6ee0ce1403d487a7f4 458 Gene3D G3DSA:3.30.1360.120 1 128 1.4E-45 T 29-03-2018 SPSF3K_RS07510 b4be0eeb987d7046deb5a6ef02cfe976 82 Gene3D G3DSA:1.10.1660.10 13 80 5.9E-7 T 29-03-2018 SPSF3K_RS07510 b4be0eeb987d7046deb5a6ef02cfe976 82 SUPERFAMILY SSF46955 29 79 1.22E-10 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS07510 b4be0eeb987d7046deb5a6ef02cfe976 82 Pfam PF12728 Helix-turn-helix domain 29 79 5.8E-10 T 29-03-2018 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Gene3D G3DSA:3.40.50.300 500 721 4.4E-52 T 29-03-2018 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 656 670 6.6E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 6.6E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 594 612 6.6E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 623 641 6.6E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 SMART SM01086 722 811 1.9E-31 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 SMART SM00382 545 685 2.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 SMART SM00382 231 376 6.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 236 368 1.6E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 SUPERFAMILY SSF52540 494 801 1.43E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 105 136 0.0015 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 51 0.0089 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Gene3D G3DSA:3.40.50.300 191 375 8.7E-23 T 29-03-2018 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 579 597 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 327 339 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Gene3D G3DSA:1.10.1780.10 2 165 9.2E-17 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Gene3D G3DSA:1.10.8.60 722 814 2.9E-23 T 29-03-2018 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 SUPERFAMILY SSF52540 194 452 7.34E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Gene3D G3DSA:1.10.8.60 376 495 4.2E-26 T 29-03-2018 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 SUPERFAMILY SSF81923 4 127 2.75E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Pfam PF07724 AAA domain (Cdc48 subfamily) 544 715 9.7E-53 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SPSF3K_RS00665 38a635662319fa64e02064ccad88ea4d 814 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 722 801 1.3E-23 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SPSF3K_RS07125 81cb3ba9f36ba75e9e8e4a3c0b06fba8 876 Gene3D G3DSA:1.10.287.620 200 317 1.7E-6 T 29-03-2018 SPSF3K_RS07125 81cb3ba9f36ba75e9e8e4a3c0b06fba8 876 Pfam PF02687 FtsX-like permease family 776 859 1.3E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SPSF3K_RS07125 81cb3ba9f36ba75e9e8e4a3c0b06fba8 876 Pfam PF02687 FtsX-like permease family 379 466 3.4E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SPSF3K_RS03035 d0fef13834fab2597cf71e17ec8ab09e 145 Gene3D G3DSA:3.90.1010.10 3 140 5.4E-44 T 29-03-2018 SPSF3K_RS03035 d0fef13834fab2597cf71e17ec8ab09e 145 Pfam PF01592 NifU-like N terminal domain 10 127 3.3E-24 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 SPSF3K_RS03035 d0fef13834fab2597cf71e17ec8ab09e 145 SUPERFAMILY SSF82649 2 141 1.86E-47 T 29-03-2018 SPSF3K_RS03035 d0fef13834fab2597cf71e17ec8ab09e 145 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 139 3.2E-51 T 29-03-2018 SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 22 188 2.8E-24 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 Gene3D G3DSA:3.40.50.300 642 823 8.8E-12 T 29-03-2018 SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 Pfam PF00929 Exonuclease 25 177 5.8E-23 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 SUPERFAMILY SSF52540 273 326 1.82E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 SUPERFAMILY SSF52540 586 600 1.82E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 SUPERFAMILY SSF52540 410 479 1.82E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 SUPERFAMILY SSF52540 628 792 1.82E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 Gene3D G3DSA:3.30.420.10 10 188 9.2E-35 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 SMART SM00491 673 800 5.5E-8 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 Pfam PF13307 Helicase C-terminal domain 660 806 2.4E-24 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 Pfam PF00270 DEAD/DEAH box helicase 279 340 1.3E-5 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 SUPERFAMILY SSF53098 22 198 5.7E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 SMART SM00479 22 186 2.4E-34 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SPSF3K_RS04535 67b5a237f7bce660b7996de4eee99840 834 Gene3D G3DSA:3.40.50.300 258 628 2.8E-22 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 Pfam PF00958 GMP synthase C terminal domain 428 519 5.0E-43 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 SUPERFAMILY SSF52402 195 413 1.39E-59 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 84 95 1.1E-7 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 57 66 1.1E-7 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 175 188 1.1E-7 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 SUPERFAMILY SSF52317 11 208 3.85E-54 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 54 68 1.7E-6 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 84 100 1.7E-6 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 13 27 1.7E-6 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 10 520 53.678 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 PRINTS PR00097 Anthranilate synthase component II signature 57 66 5.7E-6 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 PRINTS PR00097 Anthranilate synthase component II signature 175 188 5.7E-6 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 PRINTS PR00097 Anthranilate synthase component II signature 84 95 5.7E-6 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 210 520 2.5E-150 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 Gene3D G3DSA:3.40.50.880 8 218 1.1E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 Pfam PF02540 NAD synthase 219 258 7.7E-8 T 29-03-2018 IPR022310 NAD/GMP synthase SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 Pfam PF00117 Glutamine amidotransferase class-I 15 197 5.7E-43 T 29-03-2018 IPR017926 Glutamine amidotransferase SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 Gene3D G3DSA:3.30.300.10 396 520 1.1E-50 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 SUPERFAMILY SSF54810 400 520 2.48E-49 T 29-03-2018 SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 Gene3D G3DSA:3.40.50.620 219 395 2.3E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS06580 b4c9fd7237f9ac1f47da0380c9461e1e 520 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 13 202 5.1E-74 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 Pfam PF07664 Ferrous iron transport protein B C terminus 455 507 7.3E-15 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 3.2E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 3.2E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 Pfam PF02421 Ferrous iron transport protein B 3 155 1.8E-61 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 SUPERFAMILY SSF52540 3 164 8.9E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 Pfam PF07670 Nucleoside recognition 351 444 3.2E-11 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 Pfam PF07670 Nucleoside recognition 512 641 8.1E-28 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 Gene3D G3DSA:3.40.50.300 1 297 4.3E-30 T 29-03-2018 SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 157 3.6E-12 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS08845 30d404e04f1a3f4f8c30e9f46fd529ee 717 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 637 1.8E-164 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 144 1.9E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 Pfam PF16193 AAA C-terminal domain 173 251 1.6E-22 T 29-03-2018 IPR032423 AAA C-terminal domain SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 SMART SM00382 38 150 3.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 Gene3D G3DSA:1.20.272.10 236 329 8.2E-32 T 29-03-2018 SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 Gene3D G3DSA:1.10.8.60 139 227 9.0E-21 T 29-03-2018 SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 Gene3D G3DSA:1.10.3710.10 332 423 1.3E-29 T 29-03-2018 SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 Pfam PF12002 MgsA AAA+ ATPase C terminal 252 416 2.6E-61 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 SUPERFAMILY SSF48019 237 420 2.32E-66 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 Gene3D G3DSA:3.40.50.300 2 138 1.6E-26 T 29-03-2018 SPSF3K_RS02405 26e547b145885a0e17506e2f545f74d5 423 SUPERFAMILY SSF52540 4 211 3.36E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05790 7bd16cc7b2e406891c45414143934320 131 Pfam PF02566 OsmC-like protein 22 124 6.3E-20 T 29-03-2018 IPR003718 OsmC/Ohr family SPSF3K_RS05790 7bd16cc7b2e406891c45414143934320 131 Gene3D G3DSA:3.30.300.20 2 130 1.1E-25 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS05790 7bd16cc7b2e406891c45414143934320 131 SUPERFAMILY SSF82784 6 127 4.19E-33 T 29-03-2018 IPR003718 OsmC/Ohr family SPSF3K_RS01445 e6a70cb45c1828d64627b65c32397784 101 TIGRFAM TIGR01608 citD: citrate lyase acyl carrier protein 1 93 1.7E-36 T 29-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 SPSF3K_RS01445 e6a70cb45c1828d64627b65c32397784 101 ProDom PD015389 LYASE CITRATE ACYL CARRIER GAMMA CHAIN CITD PRECURSOR SIGNAL DIRECT 1 77 3.0E-22 T 29-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 SPSF3K_RS01445 e6a70cb45c1828d64627b65c32397784 101 Hamap MF_00805 Citrate lyase acyl carrier protein [citD]. 1 96 26.697 T 29-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 SPSF3K_RS01445 e6a70cb45c1828d64627b65c32397784 101 PIRSF PIRSF002736 1 96 3.6E-41 T 29-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 SPSF3K_RS01445 e6a70cb45c1828d64627b65c32397784 101 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 4 85 2.3E-31 T 29-03-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein SPSF3K_RS06845 490a4dfa4f5b617830de17120fb99493 330 SUPERFAMILY SSF52283 2 135 1.06E-31 T 29-03-2018 SPSF3K_RS06845 490a4dfa4f5b617830de17120fb99493 330 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SPSF3K_RS06845 490a4dfa4f5b617830de17120fb99493 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 18 330 1.3E-25 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 SPSF3K_RS06845 490a4dfa4f5b617830de17120fb99493 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 298 3.9E-50 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 SPSF3K_RS06845 490a4dfa4f5b617830de17120fb99493 330 Gene3D G3DSA:3.40.50.720 115 301 4.7E-47 T 29-03-2018 SPSF3K_RS06845 490a4dfa4f5b617830de17120fb99493 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site SPSF3K_RS06845 490a4dfa4f5b617830de17120fb99493 330 SUPERFAMILY SSF51735 102 299 6.52E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06845 490a4dfa4f5b617830de17120fb99493 330 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 175 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 SPSF3K_RS06845 490a4dfa4f5b617830de17120fb99493 330 Gene3D G3DSA:3.40.50.720 6 114 5.7E-17 T 29-03-2018 SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 SUPERFAMILY SSF48334 24 278 9.16E-25 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 TIGRFAM TIGR01069 mutS2: MutS2 family protein 4 776 6.9E-212 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 Pfam PF01713 Smr domain 703 777 4.2E-20 T 29-03-2018 IPR002625 Smr domain SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 SMART SM00463 700 778 6.1E-18 T 29-03-2018 IPR002625 Smr domain SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 SUPERFAMILY SSF52540 287 506 3.77E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 Pfam PF00488 MutS domain V 324 504 2.8E-34 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 SUPERFAMILY SSF160443 701 776 8.5E-11 T 29-03-2018 IPR002625 Smr domain SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 PIRSF PIRSF005814 1 778 3.2E-249 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 Gene3D G3DSA:3.40.50.300 287 552 2.4E-31 T 29-03-2018 SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 777 19.617 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 403 419 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 SMART SM00533 9 310 5.0E-6 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS01605 2680f3b25c9040bba6cabe785ae6b7e9 778 SMART SM00534 321 506 1.8E-64 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 Gene3D G3DSA:1.10.1050.10 1 98 1.5E-36 T 29-03-2018 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 Pfam PF01479 S4 domain 93 140 2.0E-22 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 35.031 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 SUPERFAMILY SSF55174 3 201 5.5E-68 T 29-03-2018 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 SMART SM00363 93 157 7.7E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 92 2.1E-25 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 7.9E-76 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 Gene3D G3DSA:1.10.1050.10 142 201 1.0E-11 T 29-03-2018 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 ProSitePatterns PS00632 Ribosomal protein S4 signature. 91 115 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 Gene3D G3DSA:3.10.290.10 99 141 5.3E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS00160 f149536d49de85a922c5916f8ba76c06 203 SMART SM01390 3 92 5.0E-39 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 SPSF3K_RS08355 f19e91bcc2b795e5e37941bab1b43bf1 218 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS08355 f19e91bcc2b795e5e37941bab1b43bf1 218 Pfam PF00005 ABC transporter 19 162 5.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08355 f19e91bcc2b795e5e37941bab1b43bf1 218 SUPERFAMILY SSF52540 3 211 2.03E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08355 f19e91bcc2b795e5e37941bab1b43bf1 218 Gene3D G3DSA:3.40.50.300 1 216 7.3E-60 T 29-03-2018 SPSF3K_RS08355 f19e91bcc2b795e5e37941bab1b43bf1 218 SMART SM00382 28 212 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02835 8817047c9dcacf1a4349b12cd8fcefa5 181 Hamap MF_01572 UPF0397 protein . 2 181 27.171 T 29-03-2018 IPR022914 Protein of unknown function UPF0397 SPSF3K_RS02835 8817047c9dcacf1a4349b12cd8fcefa5 181 Pfam PF07155 ECF-type riboflavin transporter, S component 4 170 2.6E-52 T 29-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 SPSF3K_RS02095 f3dd88ed52040a72e074520f2d75b56b 257 PIRSF PIRSF000371 1 55 2.4E-25 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 SPSF3K_RS02095 f3dd88ed52040a72e074520f2d75b56b 257 PIRSF PIRSF000371 50 256 2.0E-55 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 SPSF3K_RS02095 f3dd88ed52040a72e074520f2d75b56b 257 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 57 250 1.1E-61 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 SPSF3K_RS02095 f3dd88ed52040a72e074520f2d75b56b 257 Gene3D G3DSA:3.80.30.10 82 257 3.4E-36 T 29-03-2018 SPSF3K_RS02095 f3dd88ed52040a72e074520f2d75b56b 257 Pfam PF13353 4Fe-4S single cluster domain 17 163 1.6E-15 T 29-03-2018 SPSF3K_RS02095 f3dd88ed52040a72e074520f2d75b56b 257 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 SPSF3K_RS02095 f3dd88ed52040a72e074520f2d75b56b 257 SUPERFAMILY SSF102114 27 225 1.57E-22 T 29-03-2018 SPSF3K_RS02095 f3dd88ed52040a72e074520f2d75b56b 257 Pfam PF04055 Radical SAM superfamily 25 189 1.2E-27 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 Gene3D G3DSA:3.40.50.1360 55 230 1.2E-37 T 29-03-2018 SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 SUPERFAMILY SSF100950 64 216 1.88E-33 T 29-03-2018 SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 Pfam PF00455 DeoR C terminal sensor domain 65 217 2.2E-45 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 Pfam PF08220 DeoR-like helix-turn-helix domain 2 51 6.9E-13 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 SUPERFAMILY SSF46785 4 62 4.69E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 SMART SM00420 1 48 4.2E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 Gene3D G3DSA:1.10.10.10 1 48 1.4E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 14 28 4.2E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 28 46 4.2E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS05315 e9469153998a4a043d2301276b851801 237 SMART SM01134 63 220 7.5E-63 T 29-03-2018 SPSF3K_RS00915 908a3147d07d6f39e874b49dadf46c9e 175 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 172 2.9E-45 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SPSF3K_RS00915 908a3147d07d6f39e874b49dadf46c9e 175 SUPERFAMILY SSF100950 1 172 2.09E-44 T 29-03-2018 SPSF3K_RS00915 908a3147d07d6f39e874b49dadf46c9e 175 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 172 4.0E-38 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SPSF3K_RS00915 908a3147d07d6f39e874b49dadf46c9e 175 Gene3D G3DSA:3.40.50.10420 1 174 4.7E-45 T 29-03-2018 SPSF3K_RS00915 908a3147d07d6f39e874b49dadf46c9e 175 PIRSF PIRSF006806 1 175 5.2E-40 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase SPSF3K_RS09585 66d80ebf75c8094f35e2251fe2471629 319 SUPERFAMILY SSF53098 160 311 8.91E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS09585 66d80ebf75c8094f35e2251fe2471629 319 Gene3D G3DSA:3.30.420.10 152 316 6.1E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS09585 66d80ebf75c8094f35e2251fe2471629 319 Pfam PF00665 Integrase core domain 161 265 2.6E-7 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SPSF3K_RS09585 66d80ebf75c8094f35e2251fe2471629 319 Gene3D G3DSA:1.10.10.60 3 43 8.6E-7 T 29-03-2018 SPSF3K_RS07805 e3d0038da908a463e6237e9374d5ce98 388 Pfam PF07690 Major Facilitator Superfamily 11 245 2.6E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS07805 e3d0038da908a463e6237e9374d5ce98 388 SUPERFAMILY SSF103473 4 380 6.28E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS07805 e3d0038da908a463e6237e9374d5ce98 388 Gene3D G3DSA:1.20.1250.20 1 193 1.8E-15 T 29-03-2018 SPSF3K_RS07805 e3d0038da908a463e6237e9374d5ce98 388 Gene3D G3DSA:1.20.1250.20 210 383 7.9E-16 T 29-03-2018 SPSF3K_RS04155 54ef496f1edb83e834a629a957d45868 269 Pfam PF00753 Metallo-beta-lactamase superfamily 15 223 1.3E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS04155 54ef496f1edb83e834a629a957d45868 269 Gene3D G3DSA:3.60.15.10 12 267 2.9E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS04155 54ef496f1edb83e834a629a957d45868 269 SUPERFAMILY SSF56281 12 252 1.57E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS04155 54ef496f1edb83e834a629a957d45868 269 SMART SM00849 16 196 4.2E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS01225 f81d4bbcd2ab3c39629cc796d6b92d78 448 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 445 4.8E-170 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPSF3K_RS01225 f81d4bbcd2ab3c39629cc796d6b92d78 448 SMART SM01230 106 358 1.5E-130 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPSF3K_RS01225 f81d4bbcd2ab3c39629cc796d6b92d78 448 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 99 4.7E-28 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPSF3K_RS01225 f81d4bbcd2ab3c39629cc796d6b92d78 448 SUPERFAMILY SSF54368 4 106 1.31E-29 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPSF3K_RS01225 f81d4bbcd2ab3c39629cc796d6b92d78 448 Pfam PF00120 Glutamine synthetase, catalytic domain 107 444 1.2E-137 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPSF3K_RS01225 f81d4bbcd2ab3c39629cc796d6b92d78 448 Gene3D G3DSA:3.30.590.10 106 448 1.0E-122 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 SPSF3K_RS01225 f81d4bbcd2ab3c39629cc796d6b92d78 448 SUPERFAMILY SSF55931 106 445 5.2E-123 T 29-03-2018 SPSF3K_RS01225 f81d4bbcd2ab3c39629cc796d6b92d78 448 Gene3D G3DSA:3.10.20.70 1 105 2.7E-32 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPSF3K_RS01225 f81d4bbcd2ab3c39629cc796d6b92d78 448 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 SPSF3K_RS08330 06ae203cd13ef5b576a9a6eb57209f10 238 SUPERFAMILY SSF55120 46 235 1.26E-42 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS08330 06ae203cd13ef5b576a9a6eb57209f10 238 Pfam PF01479 S4 domain 1 42 1.4E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08330 06ae203cd13ef5b576a9a6eb57209f10 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 229 5.1E-50 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPSF3K_RS08330 06ae203cd13ef5b576a9a6eb57209f10 238 SMART SM00363 1 59 1.3E-6 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08330 06ae203cd13ef5b576a9a6eb57209f10 238 Gene3D G3DSA:3.30.2350.10 70 238 1.6E-37 T 29-03-2018 SPSF3K_RS08330 06ae203cd13ef5b576a9a6eb57209f10 238 Pfam PF00849 RNA pseudouridylate synthase 62 196 3.4E-23 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS08330 06ae203cd13ef5b576a9a6eb57209f10 238 SUPERFAMILY SSF55174 1 59 3.14E-11 T 29-03-2018 SPSF3K_RS08330 06ae203cd13ef5b576a9a6eb57209f10 238 Gene3D G3DSA:3.10.290.10 1 69 2.7E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08330 06ae203cd13ef5b576a9a6eb57209f10 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPSF3K_RS04135 043bd0cdef37557511416a2dc7b85ac6 271 SUPERFAMILY SSF53850 6 264 1.99E-54 T 29-03-2018 SPSF3K_RS04135 043bd0cdef37557511416a2dc7b85ac6 271 Gene3D G3DSA:3.40.190.10 158 266 5.2E-11 T 29-03-2018 SPSF3K_RS04135 043bd0cdef37557511416a2dc7b85ac6 271 Gene3D G3DSA:3.40.190.10 3 157 3.0E-35 T 29-03-2018 SPSF3K_RS04135 043bd0cdef37557511416a2dc7b85ac6 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 262 3.6E-46 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS04135 043bd0cdef37557511416a2dc7b85ac6 271 SMART SM00062 45 266 5.1E-50 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS04455 c0379f24d17b10a9304dc5eb36a1a480 269 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 29-03-2018 SPSF3K_RS04455 c0379f24d17b10a9304dc5eb36a1a480 269 SUPERFAMILY SSF56784 1 268 6.24E-78 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04455 c0379f24d17b10a9304dc5eb36a1a480 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 236 2.7E-27 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS04455 c0379f24d17b10a9304dc5eb36a1a480 269 Gene3D G3DSA:3.40.50.1000 1 269 1.9E-42 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04455 c0379f24d17b10a9304dc5eb36a1a480 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 263 6.2E-70 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04455 c0379f24d17b10a9304dc5eb36a1a480 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 3.1E-63 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS09895 6f6af8ac099d5b63de40f1200a7741bc 382 Gene3D G3DSA:2.30.40.10 7 67 1.1E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPSF3K_RS09895 6f6af8ac099d5b63de40f1200a7741bc 382 SUPERFAMILY SSF51338 350 381 1.33E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPSF3K_RS09895 6f6af8ac099d5b63de40f1200a7741bc 382 SUPERFAMILY SSF51338 3 52 1.33E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPSF3K_RS09895 6f6af8ac099d5b63de40f1200a7741bc 382 SUPERFAMILY SSF51556 53 350 3.63E-96 T 29-03-2018 IPR032466 Metal-dependent hydrolase SPSF3K_RS09895 6f6af8ac099d5b63de40f1200a7741bc 382 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 35 377 8.6E-94 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SPSF3K_RS09895 6f6af8ac099d5b63de40f1200a7741bc 382 Pfam PF01979 Amidohydrolase family 50 377 1.5E-19 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SPSF3K_RS09895 6f6af8ac099d5b63de40f1200a7741bc 382 Gene3D G3DSA:3.20.20.140 68 350 4.0E-98 T 29-03-2018 SPSF3K_RS09895 6f6af8ac099d5b63de40f1200a7741bc 382 PIRSF PIRSF038994 1 382 1.7E-119 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 Gene3D G3DSA:3.40.50.1370 153 308 4.8E-50 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 152 1.1E-33 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 81 90 1.7E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 220 229 1.7E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 43 65 1.7E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 138 155 1.7E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 1.7E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 1.7E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 160 302 2.5E-21 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 11 304 7.2E-89 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 Gene3D G3DSA:3.40.50.1370 10 152 9.7E-42 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 8.5E-20 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 8.5E-20 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 8.5E-20 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 8.5E-20 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 10 306 38.21 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS05220 4e6e2a1ac2f1679d8c74eb5848be0e6d 310 SUPERFAMILY SSF53671 8 307 3.01E-86 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09510 f0bd4b62d85667976b8d23edf14e0dcd 453 Gene3D G3DSA:3.40.50.150 76 449 7.5E-52 T 29-03-2018 SPSF3K_RS09510 f0bd4b62d85667976b8d23edf14e0dcd 453 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 18 443 1.8E-128 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 SPSF3K_RS09510 f0bd4b62d85667976b8d23edf14e0dcd 453 SUPERFAMILY SSF53335 68 450 6.4E-71 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS09510 f0bd4b62d85667976b8d23edf14e0dcd 453 Pfam PF01938 TRAM domain 6 60 3.5E-6 T 29-03-2018 IPR002792 TRAM domain SPSF3K_RS09510 f0bd4b62d85667976b8d23edf14e0dcd 453 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 382 413 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site SPSF3K_RS09510 f0bd4b62d85667976b8d23edf14e0dcd 453 Gene3D G3DSA:2.40.50.140 2 75 2.3E-19 T 29-03-2018 SPSF3K_RS09510 f0bd4b62d85667976b8d23edf14e0dcd 453 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 433 443 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site SPSF3K_RS09510 f0bd4b62d85667976b8d23edf14e0dcd 453 SUPERFAMILY SSF50249 4 60 6.85E-12 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS09510 f0bd4b62d85667976b8d23edf14e0dcd 453 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 90 451 5.5E-20 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 SPSF3K_RS04145 d2e5cefe11992aab641905a9bddea055 236 Pfam PF00072 Response regulator receiver domain 4 113 1.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS04145 d2e5cefe11992aab641905a9bddea055 236 SUPERFAMILY SSF52172 1 126 7.83E-43 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS04145 d2e5cefe11992aab641905a9bddea055 236 Gene3D G3DSA:1.10.10.10 130 236 3.5E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04145 d2e5cefe11992aab641905a9bddea055 236 SUPERFAMILY SSF46894 134 233 2.69E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPSF3K_RS04145 d2e5cefe11992aab641905a9bddea055 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 1.3E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS04145 d2e5cefe11992aab641905a9bddea055 236 SMART SM00448 2 112 1.6E-46 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS04145 d2e5cefe11992aab641905a9bddea055 236 Gene3D G3DSA:3.40.50.2300 1 129 5.2E-39 T 29-03-2018 SPSF3K_RS04145 d2e5cefe11992aab641905a9bddea055 236 SMART SM00862 156 232 7.0E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS00140 fe77360f007536aa759f774e2571ed73 657 PIRSF PIRSF026583 1 656 1.8E-246 T 29-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA SPSF3K_RS00140 fe77360f007536aa759f774e2571ed73 657 Gene3D G3DSA:3.30.70.1230 163 352 5.4E-4 T 29-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 SPSF3K_RS00140 fe77360f007536aa759f774e2571ed73 657 Pfam PF02272 DHHA1 domain 517 646 4.6E-14 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 SPSF3K_RS00140 fe77360f007536aa759f774e2571ed73 657 SUPERFAMILY SSF64182 339 639 4.84E-63 T 29-03-2018 SPSF3K_RS00140 fe77360f007536aa759f774e2571ed73 657 Pfam PF01368 DHH family 340 495 4.3E-20 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SPSF3K_RS00140 fe77360f007536aa759f774e2571ed73 657 Gene3D G3DSA:3.90.1640.10 353 533 4.3E-37 T 29-03-2018 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 5 427 2.3E-122 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 Pfam PF01225 Mur ligase family, catalytic domain 4 103 8.5E-26 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 Gene3D G3DSA:3.40.1190.10 92 297 4.8E-37 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 Gene3D G3DSA:3.90.190.20 298 441 2.8E-21 T 29-03-2018 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 SUPERFAMILY SSF53623 90 295 3.53E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 2 437 34.697 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 SUPERFAMILY SSF51984 4 89 1.14E-18 T 29-03-2018 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 Pfam PF08245 Mur ligase middle domain 108 275 6.5E-22 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 Pfam PF02875 Mur ligase family, glutamate ligase domain 297 378 3.5E-15 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 Gene3D G3DSA:3.40.50.720 2 90 4.8E-5 T 29-03-2018 SPSF3K_RS03275 64392d1c28d947dea247092c542fd6fb 443 SUPERFAMILY SSF53244 296 433 5.13E-34 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS02490 f11ee8274bc8371b6386e0bca724e8d2 147 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 7.9E-55 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SPSF3K_RS02490 f11ee8274bc8371b6386e0bca724e8d2 147 SUPERFAMILY SSF69500 1 144 2.22E-54 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain SPSF3K_RS02490 f11ee8274bc8371b6386e0bca724e8d2 147 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 143 8.5E-52 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SPSF3K_RS02490 f11ee8274bc8371b6386e0bca724e8d2 147 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 144 32.69 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 SPSF3K_RS02490 f11ee8274bc8371b6386e0bca724e8d2 147 Gene3D G3DSA:3.50.80.10 1 144 1.8E-52 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain SPSF3K_RS04585 8fa0ea566b0745d0f62b013ea3518c79 392 SUPERFAMILY SSF53697 17 381 3.53E-49 T 29-03-2018 SPSF3K_RS04585 8fa0ea566b0745d0f62b013ea3518c79 392 Pfam PF01380 SIS domain 234 326 4.0E-6 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS04585 8fa0ea566b0745d0f62b013ea3518c79 392 Pfam PF01380 SIS domain 57 194 7.0E-10 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS04585 8fa0ea566b0745d0f62b013ea3518c79 392 Gene3D G3DSA:3.40.50.10490 10 221 1.9E-24 T 29-03-2018 SPSF3K_RS04585 8fa0ea566b0745d0f62b013ea3518c79 392 Gene3D G3DSA:3.40.50.10490 222 384 4.1E-14 T 29-03-2018 SPSF3K_RS08090 35993ed0a0f51b4e582ce4ff828795d5 348 Gene3D G3DSA:3.40.50.720 5 195 9.6E-37 T 29-03-2018 SPSF3K_RS08090 35993ed0a0f51b4e582ce4ff828795d5 348 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 7 330 2.3E-135 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 SPSF3K_RS08090 35993ed0a0f51b4e582ce4ff828795d5 348 Gene3D G3DSA:3.90.25.10 196 348 4.5E-42 T 29-03-2018 SPSF3K_RS08090 35993ed0a0f51b4e582ce4ff828795d5 348 Pfam PF16363 GDP-mannose 4,6 dehydratase 8 318 1.7E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS08090 35993ed0a0f51b4e582ce4ff828795d5 348 SUPERFAMILY SSF51735 5 335 5.33E-93 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS02920 9609eb728b4f132dba1f78434c371912 534 SUPERFAMILY SSF52540 1 270 5.61E-125 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02920 9609eb728b4f132dba1f78434c371912 534 Gene3D G3DSA:3.40.50.880 287 533 6.6E-69 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS02920 9609eb728b4f132dba1f78434c371912 534 Pfam PF00117 Glutamine amidotransferase class-I 302 527 9.0E-55 T 29-03-2018 IPR017926 Glutamine amidotransferase SPSF3K_RS02920 9609eb728b4f132dba1f78434c371912 534 Hamap MF_01227 CTP synthase [pyrG]. 2 533 51.17 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SPSF3K_RS02920 9609eb728b4f132dba1f78434c371912 534 Gene3D G3DSA:3.40.50.300 1 286 1.3E-134 T 29-03-2018 SPSF3K_RS02920 9609eb728b4f132dba1f78434c371912 534 Pfam PF06418 CTP synthase N-terminus 3 267 1.5E-128 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SPSF3K_RS02920 9609eb728b4f132dba1f78434c371912 534 SUPERFAMILY SSF52317 289 531 2.07E-74 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS02920 9609eb728b4f132dba1f78434c371912 534 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 4.3E-251 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 SPSF3K_RS04970 9a0c5aad957f0be3362a3d6fca5ddb02 222 SMART SM00382 32 215 2.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS04970 9a0c5aad957f0be3362a3d6fca5ddb02 222 SUPERFAMILY SSF52540 3 221 4.42E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04970 9a0c5aad957f0be3362a3d6fca5ddb02 222 Pfam PF00005 ABC transporter 23 169 3.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS04970 9a0c5aad957f0be3362a3d6fca5ddb02 222 Gene3D G3DSA:3.40.50.300 1 222 8.5E-59 T 29-03-2018 SPSF3K_RS04970 9a0c5aad957f0be3362a3d6fca5ddb02 222 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 SUPERFAMILY SSF46785 1 61 4.14E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 Gene3D G3DSA:3.30.1360.40 74 146 6.5E-23 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 Pfam PF02863 Arginine repressor, C-terminal domain 81 145 3.0E-22 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 91 127 1.0E-13 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 SUPERFAMILY SSF55252 79 147 1.44E-21 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 PRINTS PR01467 Bacterial arginine repressor signature 22 35 9.2E-21 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 PRINTS PR01467 Bacterial arginine repressor signature 88 101 9.2E-21 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 PRINTS PR01467 Bacterial arginine repressor signature 118 133 9.2E-21 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 PRINTS PR01467 Bacterial arginine repressor signature 38 53 9.2E-21 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 Pfam PF01316 Arginine repressor, DNA binding domain 3 63 8.3E-23 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 Gene3D G3DSA:1.10.10.10 4 63 8.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 Hamap MF_00173 Arginine repressor [argR]. 1 152 54.597 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS09090 c46ffa669d19033e482ee4a1f17bc7bc 157 TIGRFAM TIGR01529 argR_whole: arginine repressor 6 146 4.9E-39 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS01230 cb80cdcc4db0c74b6c58d93e50d6bc33 552 Gene3D G3DSA:3.40.190.10 212 307 6.5E-18 T 29-03-2018 SPSF3K_RS01230 cb80cdcc4db0c74b6c58d93e50d6bc33 552 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 471 4.0E-72 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain SPSF3K_RS01230 cb80cdcc4db0c74b6c58d93e50d6bc33 552 PIRSF PIRSF002741 5 552 1.1E-80 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SPSF3K_RS01230 cb80cdcc4db0c74b6c58d93e50d6bc33 552 Gene3D G3DSA:3.10.105.10 308 523 7.3E-39 T 29-03-2018 SPSF3K_RS01230 cb80cdcc4db0c74b6c58d93e50d6bc33 552 Gene3D G3DSA:3.90.76.10 49 211 1.5E-35 T 29-03-2018 SPSF3K_RS01230 cb80cdcc4db0c74b6c58d93e50d6bc33 552 SUPERFAMILY SSF53850 37 543 1.23E-104 T 29-03-2018 SPSF3K_RS04260 39418128abe602118216d9646aa86615 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 3 301 2.4E-111 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 SPSF3K_RS04260 39418128abe602118216d9646aa86615 310 SUPERFAMILY SSF75138 2 130 2.62E-41 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SPSF3K_RS04260 39418128abe602118216d9646aa86615 310 SUPERFAMILY SSF53795 132 298 4.58E-38 T 29-03-2018 SPSF3K_RS04260 39418128abe602118216d9646aa86615 310 Gene3D G3DSA:3.40.50.300 135 307 4.7E-41 T 29-03-2018 SPSF3K_RS04260 39418128abe602118216d9646aa86615 310 Gene3D G3DSA:3.40.1390.20 2 132 1.7E-43 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SPSF3K_RS04260 39418128abe602118216d9646aa86615 310 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 7.4E-72 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 SPSF3K_RS04260 39418128abe602118216d9646aa86615 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 2 306 41.284 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 SPSF3K_RS04260 39418128abe602118216d9646aa86615 310 Pfam PF02603 HPr Serine kinase N terminus 3 127 3.0E-42 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 57.074 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 SMART SM00382 147 332 1.4E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 77 7.3E-21 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 Gene3D G3DSA:1.10.1140.10 354 464 5.9E-40 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 SUPERFAMILY SSF47917 351 467 3.14E-51 T 29-03-2018 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 1.8E-252 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 SUPERFAMILY SSF52540 81 353 8.67E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 Gene3D G3DSA:3.40.50.300 80 353 1.7E-91 T 29-03-2018 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 Gene3D G3DSA:2.40.10.170 1 79 5.1E-28 T 29-03-2018 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 348 4.8E-67 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04910 9bb6665bda4d83ac90fd5a3bb39deb61 468 SUPERFAMILY SSF50615 2 78 1.36E-22 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS02430 8b56ddf182fa30017b315dccddb8db57 317 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 4 307 1.4E-108 T 29-03-2018 SPSF3K_RS02430 8b56ddf182fa30017b315dccddb8db57 317 PIRSF PIRSF000401 2 309 7.9E-107 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 SPSF3K_RS02430 8b56ddf182fa30017b315dccddb8db57 317 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 4 307 33.629 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 SPSF3K_RS02430 8b56ddf182fa30017b315dccddb8db57 317 Gene3D G3DSA:3.40.50.150 113 314 1.6E-35 T 29-03-2018 SPSF3K_RS02430 8b56ddf182fa30017b315dccddb8db57 317 SUPERFAMILY SSF53335 63 304 4.26E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS02430 8b56ddf182fa30017b315dccddb8db57 317 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 4 300 2.5E-71 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 SPSF3K_RS03610 b74d200add76d99f53bddf1fc7143937 289 Gene3D G3DSA:1.10.3470.10 1 278 1.2E-54 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS03610 b74d200add76d99f53bddf1fc7143937 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 273 8.2E-47 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPSF3K_RS05175 bcce4cc698ab44cb2b6663a1ab0e365a 399 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 55 301 3.6E-68 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA SPSF3K_RS05175 bcce4cc698ab44cb2b6663a1ab0e365a 399 Gene3D G3DSA:3.60.21.10 38 398 6.3E-52 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS05175 bcce4cc698ab44cb2b6663a1ab0e365a 399 SMART SM00854 54 301 2.9E-83 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA SPSF3K_RS05175 bcce4cc698ab44cb2b6663a1ab0e365a 399 SUPERFAMILY SSF56300 54 307 3.8E-39 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS02840 ebe7612c50081408129ca40f4f355572 280 Gene3D G3DSA:3.40.50.10790 4 166 1.3E-50 T 29-03-2018 SPSF3K_RS02840 ebe7612c50081408129ca40f4f355572 280 SUPERFAMILY SSF101852 170 276 6.28E-28 T 29-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal SPSF3K_RS02840 ebe7612c50081408129ca40f4f355572 280 PIRSF PIRSF006779 1 278 1.6E-94 T 29-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase SPSF3K_RS02840 ebe7612c50081408129ca40f4f355572 280 SUPERFAMILY SSF102522 4 167 7.45E-52 T 29-03-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal SPSF3K_RS02840 ebe7612c50081408129ca40f4f355572 280 Gene3D G3DSA:2.40.30.90 169 278 3.5E-24 T 29-03-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal SPSF3K_RS02840 ebe7612c50081408129ca40f4f355572 280 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 6 273 1.6E-65 T 29-03-2018 IPR002747 SAM-dependent chlorinase/fluorinase SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 Gene3D G3DSA:1.20.1110.10 69 331 4.3E-35 T 29-03-2018 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 PRINTS PR00941 Cadmium-transporting ATPase signature 47 59 3.6E-9 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 PRINTS PR00941 Cadmium-transporting ATPase signature 202 216 3.6E-9 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 PRINTS PR00941 Cadmium-transporting ATPase signature 101 121 3.6E-9 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 PRINTS PR00941 Cadmium-transporting ATPase signature 183 199 3.6E-9 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 311 317 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 SUPERFAMILY SSF56784 363 608 7.73E-47 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 SUPERFAMILY SSF56784 309 327 7.73E-47 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 Pfam PF00702 haloacid dehalogenase-like hydrolase 305 521 8.4E-33 T 29-03-2018 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 66 610 1.3E-161 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 2.7E-20 T 29-03-2018 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 526 2.7E-20 T 29-03-2018 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 309 323 2.7E-20 T 29-03-2018 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 542 2.7E-20 T 29-03-2018 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 Gene3D G3DSA:3.40.50.1000 433 571 8.3E-39 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 Gene3D G3DSA:3.40.1110.10 332 432 3.1E-20 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 ProSitePatterns PS01229 Hypothetical cof family signature 2. 507 529 - T 29-03-2018 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 SUPERFAMILY SSF81665 556 590 9.81E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 SUPERFAMILY SSF81665 218 303 9.81E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 SUPERFAMILY SSF81665 71 120 9.81E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 48 610 1.8E-120 T 29-03-2018 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 Pfam PF00122 E1-E2 ATPase 121 289 4.3E-42 T 29-03-2018 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 593 1.4E-73 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS09445 e619846a8b26af38cb2b486ad82e4d3c 616 SUPERFAMILY SSF81653 122 217 3.92E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SPSF3K_RS08565 a8d3a9d4746d0ac7f4b8141f1d29497c 416 SUPERFAMILY SSF81340 6 405 3.66E-58 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS08565 a8d3a9d4746d0ac7f4b8141f1d29497c 416 Gene3D G3DSA:1.10.3080.10 2 408 2.3E-49 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS08565 a8d3a9d4746d0ac7f4b8141f1d29497c 416 Pfam PF00654 Voltage gated chloride channel 69 401 5.6E-46 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS03465 60f85fb14225b729e1230a6697fb8ad3 89 Gene3D G3DSA:1.10.10.60 11 49 8.8E-4 T 29-03-2018 SPSF3K_RS03465 60f85fb14225b729e1230a6697fb8ad3 89 Gene3D G3DSA:1.10.10.10 50 87 9.0E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03465 60f85fb14225b729e1230a6697fb8ad3 89 SUPERFAMILY SSF46955 37 87 1.7E-8 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS03465 60f85fb14225b729e1230a6697fb8ad3 89 Pfam PF01381 Helix-turn-helix 37 70 2.4E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS04925 59e15ec958d167588c499f06accf3832 423 Gene3D G3DSA:3.65.10.10 221 423 1.1E-45 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SPSF3K_RS04925 59e15ec958d167588c499f06accf3832 423 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 419 3.5E-164 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS04925 59e15ec958d167588c499f06accf3832 423 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 420 42.898 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS04925 59e15ec958d167588c499f06accf3832 423 Gene3D G3DSA:3.65.10.10 22 220 1.8E-49 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SPSF3K_RS04925 59e15ec958d167588c499f06accf3832 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 410 2.4E-109 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SPSF3K_RS04925 59e15ec958d167588c499f06accf3832 423 SUPERFAMILY SSF55205 7 422 1.96E-134 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SPSF3K_RS01760 df60eb6a38d717007fb51bccafa22673 150 Gene3D G3DSA:3.40.50.620 1 150 8.9E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS01760 df60eb6a38d717007fb51bccafa22673 150 PIRSF PIRSF006276 1 147 4.4E-20 T 29-03-2018 IPR006015 Universal stress protein A SPSF3K_RS01760 df60eb6a38d717007fb51bccafa22673 150 SUPERFAMILY SSF52402 5 146 4.1E-31 T 29-03-2018 SPSF3K_RS01760 df60eb6a38d717007fb51bccafa22673 150 PRINTS PR01438 Universal stress protein signature 5 23 2.0E-16 T 29-03-2018 IPR006015 Universal stress protein A SPSF3K_RS01760 df60eb6a38d717007fb51bccafa22673 150 PRINTS PR01438 Universal stress protein signature 122 144 2.0E-16 T 29-03-2018 IPR006015 Universal stress protein A SPSF3K_RS01760 df60eb6a38d717007fb51bccafa22673 150 PRINTS PR01438 Universal stress protein signature 104 116 2.0E-16 T 29-03-2018 IPR006015 Universal stress protein A SPSF3K_RS01760 df60eb6a38d717007fb51bccafa22673 150 Pfam PF00582 Universal stress protein family 5 144 1.0E-32 T 29-03-2018 IPR006016 UspA GO:0006950 SPSF3K_RS02805 ccba9cddb6da67757a8448a69d2f1d38 287 Pfam PF00746 LPXTG cell wall anchor motif 251 283 1.3E-6 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor SPSF3K_RS02805 ccba9cddb6da67757a8448a69d2f1d38 287 Pfam PF04650 YSIRK type signal peptide 6 28 6.8E-5 T 29-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPSF3K_RS02805 ccba9cddb6da67757a8448a69d2f1d38 287 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 254 285 1.9E-6 T 29-03-2018 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 Gene3D G3DSA:3.30.70.260 659 738 8.5E-8 T 29-03-2018 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 Pfam PF02824 TGS domain 395 454 1.1E-20 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 SUPERFAMILY SSF55021 661 736 4.58E-8 T 29-03-2018 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 Pfam PF04607 Region found in RelA / SpoT proteins 240 348 1.2E-36 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 Pfam PF13328 HD domain 31 180 4.0E-48 T 29-03-2018 IPR003607 HD/PDEase domain SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 SMART SM00954 240 349 5.5E-61 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 SMART SM00471 46 158 9.8E-9 T 29-03-2018 IPR003607 HD/PDEase domain SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 SUPERFAMILY SSF109604 10 196 5.02E-75 T 29-03-2018 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 Gene3D G3DSA:3.30.460.10 197 329 6.7E-43 T 29-03-2018 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 SUPERFAMILY SSF81301 199 370 5.56E-63 T 29-03-2018 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 736 5.3E-238 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 SUPERFAMILY SSF81271 382 455 1.85E-19 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 Pfam PF13291 ACT domain 658 736 1.0E-18 T 29-03-2018 IPR002912 ACT domain SPSF3K_RS02485 370f3aae0f29bb8437ada8aca51199f2 739 Gene3D G3DSA:3.10.20.30 389 461 1.8E-21 T 29-03-2018 IPR012675 Beta-grasp domain SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 221 399 6.7E-36 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 2.3E-34 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 2.3E-34 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 2.3E-34 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 2.3E-34 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 2.3E-34 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 SUPERFAMILY SSF55681 117 419 2.28E-109 T 29-03-2018 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 Gene3D G3DSA:3.30.930.10 106 425 5.4E-104 T 29-03-2018 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 6.8E-177 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 Gene3D G3DSA:1.10.287.40 2 105 2.8E-20 T 29-03-2018 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 42.513 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 SUPERFAMILY SSF46589 1 113 1.62E-28 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 1.9E-27 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 SPSF3K_RS10050 3b0ad8802539251c631699e689685c86 425 PIRSF PIRSF001529 1 425 4.7E-184 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 SPSF3K_RS02680 a35ce31f85b90d8c653e9724436097a1 148 Gene3D G3DSA:3.90.1180.10 1 147 2.8E-59 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS02680 a35ce31f85b90d8c653e9724436097a1 148 ProSitePatterns PS00783 Ribosomal protein L13 signature. 107 129 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS02680 a35ce31f85b90d8c653e9724436097a1 148 PIRSF PIRSF002181 1 147 3.7E-47 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS02680 a35ce31f85b90d8c653e9724436097a1 148 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 144 5.2E-58 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS02680 a35ce31f85b90d8c653e9724436097a1 148 SUPERFAMILY SSF52161 6 144 3.01E-56 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS02680 a35ce31f85b90d8c653e9724436097a1 148 Pfam PF00572 Ribosomal protein L13 16 140 3.1E-53 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS02680 a35ce31f85b90d8c653e9724436097a1 148 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 17 143 26.028 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS01405 a00a55d2783367c357e6ffac0b5da15e 349 SUPERFAMILY SSF55729 30 119 1.82E-9 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS01405 a00a55d2783367c357e6ffac0b5da15e 349 PIRSF PIRSF005751 2 346 9.0E-129 T 29-03-2018 IPR005216 Citrate lyase ligase GO:0008771 SPSF3K_RS01405 a00a55d2783367c357e6ffac0b5da15e 349 SUPERFAMILY SSF52374 151 332 1.19E-20 T 29-03-2018 SPSF3K_RS01405 a00a55d2783367c357e6ffac0b5da15e 349 Gene3D G3DSA:3.40.50.620 140 349 1.8E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS01405 a00a55d2783367c357e6ffac0b5da15e 349 Gene3D G3DSA:3.40.630.30 8 137 4.6E-8 T 29-03-2018 SPSF3K_RS01405 a00a55d2783367c357e6ffac0b5da15e 349 TIGRFAM TIGR00124 cit_ly_ligase: [citrate (pro-3S)-lyase] ligase 12 333 3.0E-91 T 29-03-2018 IPR005216 Citrate lyase ligase GO:0008771 SPSF3K_RS01405 a00a55d2783367c357e6ffac0b5da15e 349 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 111 327 7.0E-78 T 29-03-2018 SPSF3K_RS01405 a00a55d2783367c357e6ffac0b5da15e 349 SMART SM00764 148 328 2.4E-116 T 29-03-2018 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 SPSF3K_RS01405 a00a55d2783367c357e6ffac0b5da15e 349 Pfam PF08218 Citrate lyase ligase C-terminal domain 149 328 4.5E-79 T 29-03-2018 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 SPSF3K_RS00615 c4b5f2c1af9fb8455b35f6c2fa0cd3dd 414 Gene3D G3DSA:3.40.190.10 46 391 2.1E-4 T 29-03-2018 SPSF3K_RS00615 c4b5f2c1af9fb8455b35f6c2fa0cd3dd 414 SMART SM00892 139 334 0.0035 T 29-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SPSF3K_RS00615 c4b5f2c1af9fb8455b35f6c2fa0cd3dd 414 Pfam PF13930 DNA/RNA non-specific endonuclease 146 285 1.9E-19 T 29-03-2018 SPSF3K_RS01350 e4357949820484aa3bcf2a86177cc527 286 SUPERFAMILY SSF53697 99 261 6.67E-22 T 29-03-2018 SPSF3K_RS01350 e4357949820484aa3bcf2a86177cc527 286 Gene3D G3DSA:3.40.50.10490 85 280 7.6E-24 T 29-03-2018 SPSF3K_RS01350 e4357949820484aa3bcf2a86177cc527 286 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 75 1.4E-16 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SPSF3K_RS01350 e4357949820484aa3bcf2a86177cc527 286 SUPERFAMILY SSF46689 8 74 3.58E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS01350 e4357949820484aa3bcf2a86177cc527 286 Pfam PF01380 SIS domain 129 238 1.3E-13 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS01350 e4357949820484aa3bcf2a86177cc527 286 Gene3D G3DSA:1.10.10.10 1 80 3.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10190 22e65f933f007572bebf9ea2b42ad9c5 225 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 225 18.851 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10190 22e65f933f007572bebf9ea2b42ad9c5 225 Gene3D G3DSA:3.30.470.20 101 221 1.5E-25 T 29-03-2018 SPSF3K_RS10190 22e65f933f007572bebf9ea2b42ad9c5 225 SUPERFAMILY SSF56104 1 213 1.37E-47 T 29-03-2018 SPSF3K_RS10190 22e65f933f007572bebf9ea2b42ad9c5 225 Gene3D G3DSA:3.30.200.20 1 100 7.8E-20 T 29-03-2018 SPSF3K_RS10190 22e65f933f007572bebf9ea2b42ad9c5 225 Pfam PF01259 SAICAR synthetase 3 209 6.4E-30 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 Gene3D G3DSA:2.30.40.10 1 58 5.1E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 Pfam PF01979 Amidohydrolase family 50 419 1.5E-31 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 423 37.57 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 SUPERFAMILY SSF51338 2 53 3.29E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 SUPERFAMILY SSF51338 366 422 3.29E-25 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 19 422 3.6E-108 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 SUPERFAMILY SSF51556 54 364 9.26E-91 T 29-03-2018 IPR032466 Metal-dependent hydrolase SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 Gene3D G3DSA:3.20.20.140 59 410 1.5E-90 T 29-03-2018 SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS07610 20afdb9031064132bfffc353068deb88 424 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 213.367 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 2.0E-189 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 SUPERFAMILY SSF52540 1 427 1.04E-176 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 Gene3D G3DSA:3.40.440.10 150 264 5.6E-28 T 29-03-2018 SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 Gene3D G3DSA:3.40.440.10 1 149 2.1E-53 T 29-03-2018 SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 SMART SM00788 3 422 2.1E-297 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 Gene3D G3DSA:3.90.170.10 265 429 3.5E-69 T 29-03-2018 SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.1E-184 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SPSF3K_RS02085 619be9408eb02e9e31ee0ce6c97f0005 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 141 180 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 SUPERFAMILY SSF53187 4 213 1.07E-68 T 29-03-2018 SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 SUPERFAMILY SSF53187 325 406 1.07E-68 T 29-03-2018 SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 PIRSF PIRSF037215 1 407 2.8E-179 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 SUPERFAMILY SSF55031 212 323 9.94E-39 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 Gene3D G3DSA:3.40.630.10 1 407 5.1E-41 T 29-03-2018 SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 405 1.8E-192 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 Pfam PF07687 Peptidase dimerisation domain 210 305 1.2E-8 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 77 86 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 Hamap MF_00550 Peptidase T [pepT]. 3 407 55.814 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 SPSF3K_RS05085 ab0829397c802e6932c081e496f65f54 407 Pfam PF01546 Peptidase family M20/M25/M40 142 405 5.3E-10 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 SMART SM00448 4 117 1.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 Pfam PF00072 Response regulator receiver domain 6 118 9.9E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 3.7E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 SUPERFAMILY SSF52172 3 129 4.41E-30 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 Gene3D G3DSA:1.10.10.10 161 208 3.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 Gene3D G3DSA:1.20.5.430 136 160 0.0016 T 29-03-2018 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 SMART SM00421 145 202 6.7E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 Gene3D G3DSA:3.40.50.2300 3 135 1.5E-32 T 29-03-2018 SPSF3K_RS09625 ecbfad50ff5ea53bc2d99fe25872c661 213 SUPERFAMILY SSF46894 141 209 2.24E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPSF3K_RS06210 a1466013ea1afa19bf99f76d7fdc92cd 205 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 192 6.4E-42 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS06210 a1466013ea1afa19bf99f76d7fdc92cd 205 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SPSF3K_RS06210 a1466013ea1afa19bf99f76d7fdc92cd 205 PIRSF PIRSF000709 2 157 1.1E-10 T 29-03-2018 SPSF3K_RS06210 a1466013ea1afa19bf99f76d7fdc92cd 205 SMART SM00855 4 156 1.0E-21 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS06210 a1466013ea1afa19bf99f76d7fdc92cd 205 SUPERFAMILY SSF53254 3 192 4.22E-46 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS06210 a1466013ea1afa19bf99f76d7fdc92cd 205 Gene3D G3DSA:3.40.50.1240 2 202 1.9E-43 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS01290 7ae2433498bfd235eebd096d770d3e75 173 Pfam PF04394 Protein of unknown function, DUF536 104 146 1.7E-18 T 29-03-2018 IPR007489 Domain of unknown function DUF536 SPSF3K_RS01290 7ae2433498bfd235eebd096d770d3e75 173 Gene3D G3DSA:1.10.260.40 2 159 3.4E-6 T 29-03-2018 SPSF3K_RS01290 7ae2433498bfd235eebd096d770d3e75 173 Pfam PF08279 HTH domain 6 28 5.4E-5 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 307 9.6E-100 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 SUPERFAMILY SSF118116 456 644 1.1E-51 T 29-03-2018 SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 113 6.2E-12 T 29-03-2018 SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 SMART SM01340 209 327 2.2E-50 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 SMART SM00853 460 602 1.5E-43 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 642 27.333 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 326 1.9E-35 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 SUPERFAMILY SSF55874 3 214 1.22E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 Gene3D G3DSA:3.30.230.10 214 326 1.2E-27 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 Gene3D G3DSA:3.30.565.10 2 210 3.1E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 SUPERFAMILY SSF54211 192 326 1.59E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS00455 627c3dc3b9611b04843aac7e2e90c67b 658 Pfam PF08676 MutL C terminal dimerisation domain 460 602 2.1E-39 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 SPSF3K_RS07855 6763a9bf081173889f34f026679f4177 328 Gene3D G3DSA:3.20.20.100 1 327 2.2E-99 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS07855 6763a9bf081173889f34f026679f4177 328 Pfam PF00248 Aldo/keto reductase family 15 318 2.0E-73 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS07855 6763a9bf081173889f34f026679f4177 328 SUPERFAMILY SSF51430 1 323 2.88E-100 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS02995 f9259caef9ec564559adaf867c3e7a18 522 SMART SM00062 27 266 5.8E-32 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS02995 f9259caef9ec564559adaf867c3e7a18 522 SUPERFAMILY SSF161098 292 491 7.33E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS02995 f9259caef9ec564559adaf867c3e7a18 522 Gene3D G3DSA:1.10.3720.10 211 511 1.2E-47 T 29-03-2018 SPSF3K_RS02995 f9259caef9ec564559adaf867c3e7a18 522 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 292 400 2.7E-19 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPSF3K_RS02995 f9259caef9ec564559adaf867c3e7a18 522 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 338 505 1.8E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS02995 f9259caef9ec564559adaf867c3e7a18 522 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 256 5.1E-36 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS02995 f9259caef9ec564559adaf867c3e7a18 522 SUPERFAMILY SSF53850 1 255 1.31E-42 T 29-03-2018 SPSF3K_RS02995 f9259caef9ec564559adaf867c3e7a18 522 Gene3D G3DSA:3.40.190.10 145 210 7.5E-8 T 29-03-2018 SPSF3K_RS02995 f9259caef9ec564559adaf867c3e7a18 522 Gene3D G3DSA:3.40.190.10 17 144 1.1E-27 T 29-03-2018 SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1173 22.24 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 SUPERFAMILY SSF52540 1 207 2.93E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 SUPERFAMILY SSF52540 970 1171 2.93E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 SMART SM00968 518 637 9.4E-36 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 Gene3D G3DSA:3.40.50.300 910 1176 1.5E-33 T 29-03-2018 SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 Gene3D G3DSA:3.40.50.300 368 669 0.064 T 29-03-2018 SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 PIRSF PIRSF005719 1 1177 1.6E-269 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 Gene3D G3DSA:1.20.120.330 233 367 0.006 T 29-03-2018 SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 SUPERFAMILY SSF75553 481 681 1.01E-49 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 Gene3D G3DSA:3.40.50.300 1 232 1.7E-41 T 29-03-2018 SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1164 6.5E-59 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 635 1.3E-24 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SPSF3K_RS04165 24f1901cb8574c5e91968d4e04262e52 1181 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1171 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SPSF3K_RS04880 d2688d3b05f73953c3123bb4347e0eb7 65 ProSitePatterns PS00605 ATP synthase c subunit signature. 30 51 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04880 d2688d3b05f73953c3123bb4347e0eb7 65 SUPERFAMILY SSF81333 5 64 2.35E-12 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPSF3K_RS04880 d2688d3b05f73953c3123bb4347e0eb7 65 Hamap MF_01396 ATP synthase subunit c [atpH]. 1 65 12.861 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04880 d2688d3b05f73953c3123bb4347e0eb7 65 Gene3D G3DSA:1.20.20.10 1 65 6.0E-11 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPSF3K_RS04880 d2688d3b05f73953c3123bb4347e0eb7 65 Pfam PF00137 ATP synthase subunit C 4 64 3.9E-6 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPSF3K_RS04880 d2688d3b05f73953c3123bb4347e0eb7 65 PRINTS PR00124 ATP synthase C subunit signature 23 38 1.2E-8 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04880 d2688d3b05f73953c3123bb4347e0eb7 65 PRINTS PR00124 ATP synthase C subunit signature 2 21 1.2E-8 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04880 d2688d3b05f73953c3123bb4347e0eb7 65 PRINTS PR00124 ATP synthase C subunit signature 40 65 1.2E-8 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS07535 4efa10bba159a2fa8cbf0bed31519caa 74 Pfam PF05339 Protein of unknown function (DUF739) 1 68 8.0E-35 T 29-03-2018 IPR008003 Protein of unknown function DUF739 SPSF3K_RS07535 4efa10bba159a2fa8cbf0bed31519caa 74 Gene3D G3DSA:1.10.260.40 8 67 1.7E-4 T 29-03-2018 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 SUPERFAMILY SSF88723 2 178 1.77E-50 T 29-03-2018 IPR029060 PIN domain-like SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 SMART SM00482 635 843 2.0E-117 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 Gene3D G3DSA:1.10.150.20 193 271 5.3E-31 T 29-03-2018 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 TIGRFAM TIGR00593 pola: DNA polymerase I 7 879 0.0 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 742 753 8.2E-81 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 680 693 8.2E-81 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 839 8.2E-81 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 604 626 8.2E-81 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 764 775 8.2E-81 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 730 8.2E-81 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 796 812 8.2E-81 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 650 673 8.2E-81 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 627 642 8.2E-81 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 SUPERFAMILY SSF53098 315 467 1.01E-24 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 SMART SM00279 181 216 1.9E-18 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 Pfam PF00476 DNA polymerase family A 500 877 1.0E-152 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 SMART SM00475 5 270 5.7E-147 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 180 273 1.9E-33 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 Gene3D G3DSA:1.20.1060.10 420 602 8.3E-50 T 29-03-2018 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 SUPERFAMILY SSF47807 179 290 8.82E-35 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 Gene3D G3DSA:3.30.70.370 603 693 1.1E-14 T 29-03-2018 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 Gene3D G3DSA:3.30.70.370 705 879 9.4E-53 T 29-03-2018 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 Gene3D G3DSA:3.40.50.1010 5 192 6.3E-63 T 29-03-2018 IPR029060 PIN domain-like SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 SUPERFAMILY SSF56672 472 879 4.78E-150 T 29-03-2018 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 ProSitePatterns PS00447 DNA polymerase family A signature. 705 724 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 SMART SM00474 305 467 2.4E-11 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SPSF3K_RS00800 fc93f118292581217356f3c95e4d06e6 879 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 178 2.0E-50 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SPSF3K_RS00895 27b29b14738c9a1719ee97488dda44cf 376 PIRSF PIRSF005962 2 371 2.2E-100 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 SPSF3K_RS00895 27b29b14738c9a1719ee97488dda44cf 376 Pfam PF01546 Peptidase family M20/M25/M40 67 351 1.9E-22 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SPSF3K_RS00895 27b29b14738c9a1719ee97488dda44cf 376 SUPERFAMILY SSF55031 173 290 4.97E-28 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SPSF3K_RS00895 27b29b14738c9a1719ee97488dda44cf 376 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 1 373 61.505 T 29-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 SPSF3K_RS00895 27b29b14738c9a1719ee97488dda44cf 376 Pfam PF07687 Peptidase dimerisation domain 174 273 1.1E-7 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SPSF3K_RS00895 27b29b14738c9a1719ee97488dda44cf 376 Gene3D G3DSA:3.40.630.10 1 272 4.7E-46 T 29-03-2018 SPSF3K_RS00895 27b29b14738c9a1719ee97488dda44cf 376 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 6 361 1.1E-85 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 SPSF3K_RS00895 27b29b14738c9a1719ee97488dda44cf 376 SUPERFAMILY SSF53187 3 189 4.79E-63 T 29-03-2018 SPSF3K_RS00895 27b29b14738c9a1719ee97488dda44cf 376 SUPERFAMILY SSF53187 291 372 4.79E-63 T 29-03-2018 SPSF3K_RS05430 d2addcc45b33a3f5a5d10ee4add390bd 388 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 264 351 1.1E-13 T 29-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 SPSF3K_RS05430 d2addcc45b33a3f5a5d10ee4add390bd 388 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 181 261 3.1E-9 T 29-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 SPSF3K_RS05430 d2addcc45b33a3f5a5d10ee4add390bd 388 SUPERFAMILY SSF53901 2 166 1.69E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS05430 d2addcc45b33a3f5a5d10ee4add390bd 388 SUPERFAMILY SSF53901 169 386 4.15E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS05430 d2addcc45b33a3f5a5d10ee4add390bd 388 Gene3D G3DSA:3.40.47.10 45 178 1.1E-10 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS05430 d2addcc45b33a3f5a5d10ee4add390bd 388 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 12 164 7.7E-12 T 29-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 SPSF3K_RS05430 d2addcc45b33a3f5a5d10ee4add390bd 388 Gene3D G3DSA:3.40.47.10 179 321 1.1E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS05430 d2addcc45b33a3f5a5d10ee4add390bd 388 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 385 7.8E-159 T 29-03-2018 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922 SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 5 538 2.7E-256 T 29-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 Gene3D G3DSA:3.20.20.80 4 115 2.5E-38 T 29-03-2018 SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 Gene3D G3DSA:2.60.40.1180 490 538 1.1E-10 T 29-03-2018 SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 SUPERFAMILY SSF51011 466 539 2.04E-15 T 29-03-2018 SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 SMART SM00642 11 407 1.3E-119 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 Gene3D G3DSA:3.20.20.80 221 489 3.8E-55 T 29-03-2018 SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 SUPERFAMILY SSF51445 6 463 8.59E-135 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 Gene3D G3DSA:3.90.400.10 116 163 3.5E-19 T 29-03-2018 SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 Pfam PF16657 Maltogenic Amylase, C-terminal domain 466 534 1.8E-9 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal SPSF3K_RS00555 2cd9982805364ad2cffcccbf4a7775ca 541 Pfam PF00128 Alpha amylase, catalytic domain 26 365 3.7E-101 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS02535 88b61a5be34da6b3cc387f53c975b13b 491 PIRSF PIRSF006005 1 489 4.8E-228 T 29-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02535 88b61a5be34da6b3cc387f53c975b13b 491 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 4 485 9.0E-225 T 29-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02535 88b61a5be34da6b3cc387f53c975b13b 491 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 16 224 1.7E-39 T 29-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SPSF3K_RS02535 88b61a5be34da6b3cc387f53c975b13b 491 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 239 434 1.8E-36 T 29-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 SPSF3K_RS02535 88b61a5be34da6b3cc387f53c975b13b 491 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 491 262.192 T 29-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02535 88b61a5be34da6b3cc387f53c975b13b 491 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 252 269 - T 29-03-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS09760 1d86210f738e0215cc743975d6043e23 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS09760 1d86210f738e0215cc743975d6043e23 247 Pfam PF00005 ABC transporter 17 168 3.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS09760 1d86210f738e0215cc743975d6043e23 247 SUPERFAMILY SSF52540 1 238 1.2E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09760 1d86210f738e0215cc743975d6043e23 247 Gene3D G3DSA:3.40.50.300 1 245 3.1E-73 T 29-03-2018 SPSF3K_RS09760 1d86210f738e0215cc743975d6043e23 247 SMART SM00382 26 216 5.0E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS09760 1d86210f738e0215cc743975d6043e23 247 PIRSF PIRSF039085 1 244 7.6E-94 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SPSF3K_RS06115 34493fec0a4c2006347ec45bff2f32c0 295 Gene3D G3DSA:3.30.43.10 5 78 1.5E-20 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SPSF3K_RS06115 34493fec0a4c2006347ec45bff2f32c0 295 SUPERFAMILY SSF56176 5 187 3.63E-47 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SPSF3K_RS06115 34493fec0a4c2006347ec45bff2f32c0 295 SUPERFAMILY SSF56194 188 293 1.7E-37 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS06115 34493fec0a4c2006347ec45bff2f32c0 295 Gene3D G3DSA:3.30.465.10 80 211 6.4E-39 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SPSF3K_RS06115 34493fec0a4c2006347ec45bff2f32c0 295 Gene3D G3DSA:3.90.78.10 212 295 6.8E-26 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS06115 34493fec0a4c2006347ec45bff2f32c0 295 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 192 291 3.3E-27 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS06115 34493fec0a4c2006347ec45bff2f32c0 295 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 16 292 1.3E-69 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS06115 34493fec0a4c2006347ec45bff2f32c0 295 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 295 94.929 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS06115 34493fec0a4c2006347ec45bff2f32c0 295 Pfam PF01565 FAD binding domain 29 157 6.6E-27 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS00790 e4d78ba49dab363f0dbf4ea3d9d7cbbe 425 Pfam PF00005 ABC transporter 46 192 2.0E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00790 e4d78ba49dab363f0dbf4ea3d9d7cbbe 425 Gene3D G3DSA:3.40.50.300 1 282 1.0E-75 T 29-03-2018 SPSF3K_RS00790 e4d78ba49dab363f0dbf4ea3d9d7cbbe 425 Pfam PF00571 CBS domain 337 390 4.3E-4 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS00790 e4d78ba49dab363f0dbf4ea3d9d7cbbe 425 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS00790 e4d78ba49dab363f0dbf4ea3d9d7cbbe 425 SMART SM00382 53 242 7.4E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00790 e4d78ba49dab363f0dbf4ea3d9d7cbbe 425 SUPERFAMILY SSF52540 40 270 6.24E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00790 e4d78ba49dab363f0dbf4ea3d9d7cbbe 425 SUPERFAMILY SSF54631 274 395 7.33E-16 T 29-03-2018 SPSF3K_RS00790 e4d78ba49dab363f0dbf4ea3d9d7cbbe 425 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 391 3.6E-143 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SPSF3K_RS00790 e4d78ba49dab363f0dbf4ea3d9d7cbbe 425 Gene3D G3DSA:3.10.580.10 283 400 1.1E-12 T 29-03-2018 SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 374 523 5.7E-55 T 29-03-2018 IPR001162 UvrC family homology region SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 27.397 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 570 8.0E-192 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 SUPERFAMILY SSF47781 502 590 1.21E-19 T 29-03-2018 IPR010994 RuvA domain 2-like SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 SMART SM00465 15 95 6.5E-21 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 Gene3D G3DSA:1.10.150.20 536 593 7.8E-13 T 29-03-2018 SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 Gene3D G3DSA:3.40.1440.10 1 98 5.2E-24 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 Pfam PF01541 GIY-YIG catalytic domain 17 90 1.0E-9 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 SUPERFAMILY SSF46600 183 235 7.32E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 SUPERFAMILY SSF82771 15 97 1.96E-22 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 Pfam PF02151 UvrB/uvrC motif 196 228 2.7E-9 T 29-03-2018 IPR001943 UVR domain GO:0005515 SPSF3K_RS07800 8b97426af7103a892f1eac8b4a3c6bd1 593 Gene3D G3DSA:4.10.860.10 175 232 1.2E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 SPSF3K_RS05905 fc0ea5c550b4cbe826ad3e325dc83c7e 90 SUPERFAMILY SSF81710 3 90 4.45E-46 T 29-03-2018 IPR015090 Bacterial epsilon antitoxin GO:0009636|GO:0015643|GO:0031342 SPSF3K_RS05905 fc0ea5c550b4cbe826ad3e325dc83c7e 90 ProDom PD063605 PLASMID EPSILON ANTITOXIN 3D-STRUCTURE ANTIDOTE DIRECT SYSTEM SEQUENCING KILLING POSTSEGREGATIONAL 10 90 1.0E-30 T 29-03-2018 IPR015090 Bacterial epsilon antitoxin GO:0009636|GO:0015643|GO:0031342 SPSF3K_RS05905 fc0ea5c550b4cbe826ad3e325dc83c7e 90 Gene3D G3DSA:1.10.8.130 4 87 1.5E-33 T 29-03-2018 IPR035569 Antitoxin epsilon/PezA domain SPSF3K_RS05905 fc0ea5c550b4cbe826ad3e325dc83c7e 90 Pfam PF08998 Bacterial epsilon antitoxin 2 90 3.3E-56 T 29-03-2018 IPR015090 Bacterial epsilon antitoxin GO:0009636|GO:0015643|GO:0031342 SPSF3K_RS00445 60f9c5df4b7d266eb793825732373a0f 277 Pfam PF01381 Helix-turn-helix 12 65 4.1E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS00445 60f9c5df4b7d266eb793825732373a0f 277 SMART SM00530 11 66 1.2E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS00445 60f9c5df4b7d266eb793825732373a0f 277 Gene3D G3DSA:1.10.3100.10 1 173 6.4E-17 T 29-03-2018 IPR027910 YdiL-like domain SPSF3K_RS00445 60f9c5df4b7d266eb793825732373a0f 277 SUPERFAMILY SSF47413 5 69 1.38E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 14 234 2.6E-17 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 Gene3D G3DSA:2.40.100.10 270 466 5.6E-64 T 29-03-2018 IPR029000 Cyclophilin-like domain SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 Pfam PF08282 haloacid dehalogenase-like hydrolase 15 261 2.7E-48 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 Gene3D G3DSA:3.40.50.1000 1 269 2.2E-31 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 367 382 7.7E-19 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 325 337 7.7E-19 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 299 314 7.7E-19 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 287 463 8.1E-47 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 SUPERFAMILY SSF56784 5 266 6.08E-56 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 14 260 1.0E-46 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 SUPERFAMILY SSF50891 284 385 6.28E-56 T 29-03-2018 IPR029000 Cyclophilin-like domain SPSF3K_RS09620 685f0a6f1b7212a4436e83886dca1fef 466 SUPERFAMILY SSF50891 413 464 6.28E-56 T 29-03-2018 IPR029000 Cyclophilin-like domain SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 Gene3D G3DSA:1.10.8.280 283 389 2.0E-37 T 29-03-2018 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 Gene3D G3DSA:3.40.50.300 390 575 6.3E-16 T 29-03-2018 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 Gene3D G3DSA:3.30.190.20 128 246 5.7E-42 T 29-03-2018 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 SMART SM00382 633 908 2.4E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 940 22.734 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 Pfam PF00005 ABC transporter 624 860 1.2E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 925 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 SUPERFAMILY SSF52540 432 571 6.48E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 SUPERFAMILY SSF52540 11 205 6.48E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 Gene3D G3DSA:3.40.50.300 37 99 1.9E-4 T 29-03-2018 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 Gene3D G3DSA:3.40.50.300 610 941 3.6E-58 T 29-03-2018 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 SUPERFAMILY SSF52540 615 913 5.76E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS01650 d61a2bed6a0733f9df05f8b1c73cbbc7 943 Gene3D G3DSA:3.40.50.300 1 36 1.2E-7 T 29-03-2018 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 SUPERFAMILY SSF55681 5 248 1.84E-78 T 29-03-2018 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 Gene3D G3DSA:1.20.5.320 706 782 8.2E-4 T 29-03-2018 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 Pfam PF01411 tRNA synthetases class II (A) 8 559 5.3E-185 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 SUPERFAMILY SSF50447 486 554 6.71E-14 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 656 698 1.2E-19 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 Gene3D G3DSA:3.30.980.10 556 705 2.8E-44 T 29-03-2018 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 Gene3D G3DSA:3.30.930.10 3 245 1.3E-84 T 29-03-2018 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 SUPERFAMILY SSF55186 555 713 1.2E-50 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 SMART SM00863 656 699 1.9E-21 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 6.8E-30 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 6.8E-30 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 6.8E-30 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 6.8E-30 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 6.8E-30 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 SUPERFAMILY SSF101353 249 443 7.45E-65 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 855 1.8E-291 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 Pfam PF02272 DHHA1 domain 736 868 1.1E-26 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 SPSF3K_RS08570 55232c2d858df9fd93e041b107bbbdc0 872 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 872 167.769 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 Gene3D G3DSA:1.25.40.10 698 952 4.2E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 SUPERFAMILY SSF48452 128 231 6.45E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 SMART SM01043 97 229 4.6E-13 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 Pfam PF03704 Bacterial transcriptional activator domain 108 228 6.6E-9 T 29-03-2018 IPR005158 Bacterial transcriptional activator domain SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 SUPERFAMILY SSF52540 244 494 1.78E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 Gene3D G3DSA:1.25.40.10 153 246 1.2E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 Gene3D G3DSA:1.10.10.10 2 93 6.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 Gene3D G3DSA:3.40.50.300 248 559 4.6E-10 T 29-03-2018 SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 Pfam PF13191 AAA ATPase domain 247 414 8.8E-14 T 29-03-2018 SPSF3K_RS04370 d2c3ed96df64f3a7ef120bc711893b57 1012 SUPERFAMILY SSF48452 718 932 1.86E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS06915 8a36bf0a0653b472c5eba85ba786b190 301 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 301 9.6E-40 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase SPSF3K_RS06915 8a36bf0a0653b472c5eba85ba786b190 301 SMART SM00046 3 133 1.2E-6 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPSF3K_RS06915 8a36bf0a0653b472c5eba85ba786b190 301 SUPERFAMILY SSF111331 1 301 3.71E-60 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SPSF3K_RS06915 8a36bf0a0653b472c5eba85ba786b190 301 Gene3D G3DSA:3.40.50.10330 1 136 5.9E-25 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SPSF3K_RS06915 8a36bf0a0653b472c5eba85ba786b190 301 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 129 9.3E-25 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPSF3K_RS08595 14a28a3cd62a17ea7a85a09f02d61355 265 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 259 7.1E-94 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08595 14a28a3cd62a17ea7a85a09f02d61355 265 Pfam PF08543 Phosphomethylpyrimidine kinase 14 258 1.4E-91 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 SPSF3K_RS08595 14a28a3cd62a17ea7a85a09f02d61355 265 Gene3D G3DSA:3.40.1190.20 2 264 1.3E-58 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS08595 14a28a3cd62a17ea7a85a09f02d61355 265 SUPERFAMILY SSF53613 5 260 2.49E-77 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS08630 866e53dce8c099c9128566c40c21f40a 311 PIRSF PIRSF007487 1 311 1.8E-79 T 29-03-2018 IPR021176 Competence-induced protein CoiA SPSF3K_RS08630 866e53dce8c099c9128566c40c21f40a 311 Pfam PF06054 Competence protein CoiA-like family 22 246 1.4E-35 T 29-03-2018 IPR010330 Competence-induced protein CoiA-like SPSF3K_RS05760 95fd483bd38af1ca4200c8ce218f71b4 190 ProSitePatterns PS00818 Dps protein family signature 1. 55 71 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 SPSF3K_RS05760 95fd483bd38af1ca4200c8ce218f71b4 190 Pfam PF00210 Ferritin-like domain 39 176 2.8E-30 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SPSF3K_RS05760 95fd483bd38af1ca4200c8ce218f71b4 190 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 55 71 1.2E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPSF3K_RS05760 95fd483bd38af1ca4200c8ce218f71b4 190 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 152 170 1.2E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPSF3K_RS05760 95fd483bd38af1ca4200c8ce218f71b4 190 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 79 95 1.2E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPSF3K_RS05760 95fd483bd38af1ca4200c8ce218f71b4 190 SUPERFAMILY SSF47240 9 180 5.84E-62 T 29-03-2018 IPR009078 Ferritin-like superfamily SPSF3K_RS05760 95fd483bd38af1ca4200c8ce218f71b4 190 Gene3D G3DSA:1.20.1260.10 6 190 1.3E-46 T 29-03-2018 IPR012347 Ferritin-related SPSF3K_RS03535 218b14148c86fbac580502c87f59ad94 263 ProSitePatterns PS01087 Radical activating enzymes signature. 24 45 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 SPSF3K_RS03535 218b14148c86fbac580502c87f59ad94 263 Pfam PF13353 4Fe-4S single cluster domain 22 148 9.3E-17 T 29-03-2018 SPSF3K_RS03535 218b14148c86fbac580502c87f59ad94 263 Pfam PF04055 Radical SAM superfamily 30 189 6.3E-30 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SPSF3K_RS03535 218b14148c86fbac580502c87f59ad94 263 PIRSF PIRSF000371 5 56 1.0E-14 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 SPSF3K_RS03535 218b14148c86fbac580502c87f59ad94 263 PIRSF PIRSF000371 50 259 1.3E-39 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 SPSF3K_RS03535 218b14148c86fbac580502c87f59ad94 263 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 13 250 1.4E-96 T 29-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 SPSF3K_RS03535 218b14148c86fbac580502c87f59ad94 263 Gene3D G3DSA:3.80.30.10 75 258 7.8E-39 T 29-03-2018 SPSF3K_RS03535 218b14148c86fbac580502c87f59ad94 263 SUPERFAMILY SSF102114 28 231 2.09E-26 T 29-03-2018 SPSF3K_RS01055 4a55bfa37eaec54196bb5e0882d4902f 149 SMART SM00850 51 148 1.5E-27 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SPSF3K_RS01055 4a55bfa37eaec54196bb5e0882d4902f 149 Pfam PF04397 LytTr DNA-binding domain 52 147 1.2E-22 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SPSF3K_RS01055 4a55bfa37eaec54196bb5e0882d4902f 149 Gene3D G3DSA:2.20.25.10 113 148 6.9E-6 T 29-03-2018 SPSF3K_RS01055 4a55bfa37eaec54196bb5e0882d4902f 149 Gene3D G3DSA:2.40.50.40 41 111 1.6E-16 T 29-03-2018 SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 Pfam PF00005 ABC transporter 311 456 6.6E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 Pfam PF00005 ABC transporter 22 172 3.0E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 SMART SM00382 31 223 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 SMART SM00382 320 504 1.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 Gene3D G3DSA:3.40.50.300 1 241 3.2E-57 T 29-03-2018 SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 SUPERFAMILY SSF52540 4 234 1.32E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 Gene3D G3DSA:3.40.50.300 288 533 1.7E-62 T 29-03-2018 SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 SUPERFAMILY SSF52540 286 526 4.7E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 ProSitePatterns PS00211 ABC transporters family signature. 428 442 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS02830 b8b1ceadc4cb36c1f3442830c05cf72e 568 Pfam PF12558 ATP-binding cassette cobalt transporter 236 302 8.4E-11 T 29-03-2018 IPR022216 ABC cobalt transporter GO:0016820 SPSF3K_RS06420 21f7f62635f03f5fe49e896418c32cbe 247 SUPERFAMILY SSF63817 35 221 9.94E-44 T 29-03-2018 IPR023365 Sortase domain SPSF3K_RS06420 21f7f62635f03f5fe49e896418c32cbe 247 Pfam PF04203 Sortase family 95 219 1.6E-25 T 29-03-2018 IPR005754 Sortase family SPSF3K_RS06420 21f7f62635f03f5fe49e896418c32cbe 247 TIGRFAM TIGR01076 sortase_fam: sortase 94 218 1.8E-18 T 29-03-2018 IPR005754 Sortase family SPSF3K_RS06420 21f7f62635f03f5fe49e896418c32cbe 247 Gene3D G3DSA:2.40.260.10 31 238 3.7E-33 T 29-03-2018 IPR023365 Sortase domain SPSF3K_RS01775 0d845490e5f5017f05be3184121902d8 182 SUPERFAMILY SSF52499 2 181 1.26E-47 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SPSF3K_RS01775 0d845490e5f5017f05be3184121902d8 182 Gene3D G3DSA:3.40.50.850 1 182 6.6E-45 T 29-03-2018 SPSF3K_RS01775 0d845490e5f5017f05be3184121902d8 182 Pfam PF00857 Isochorismatase family 4 175 5.8E-34 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SPSF3K_RS02160 fc570fc826c1b9a8218b7de1a5705d15 367 Pfam PF00005 ABC transporter 20 161 1.8E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS02160 fc570fc826c1b9a8218b7de1a5705d15 367 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS02160 fc570fc826c1b9a8218b7de1a5705d15 367 Gene3D G3DSA:3.40.50.300 1 237 2.7E-69 T 29-03-2018 SPSF3K_RS02160 fc570fc826c1b9a8218b7de1a5705d15 367 SMART SM00382 28 211 3.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02160 fc570fc826c1b9a8218b7de1a5705d15 367 Pfam PF08402 TOBE domain 284 352 1.0E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SPSF3K_RS02160 fc570fc826c1b9a8218b7de1a5705d15 367 Gene3D G3DSA:2.40.50.100 239 297 9.4E-7 T 29-03-2018 SPSF3K_RS02160 fc570fc826c1b9a8218b7de1a5705d15 367 SUPERFAMILY SSF52540 4 242 2.66E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02160 fc570fc826c1b9a8218b7de1a5705d15 367 Gene3D G3DSA:2.40.50.140 298 349 1.9E-9 T 29-03-2018 SPSF3K_RS02160 fc570fc826c1b9a8218b7de1a5705d15 367 SUPERFAMILY SSF50331 236 365 1.29E-21 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 SUPERFAMILY SSF46689 140 181 1.25E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 Gene3D G3DSA:1.20.5.40 107 132 1.2E-16 T 29-03-2018 SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 Gene3D G3DSA:3.40.50.1390 1 106 2.2E-33 T 29-03-2018 SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 Gene3D G3DSA:1.10.10.60 133 184 6.4E-11 T 29-03-2018 SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 SMART SM00857 2 138 5.8E-58 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 Pfam PF02796 Helix-turn-helix domain of resolvase 140 183 2.4E-14 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 Pfam PF00239 Resolvase, N terminal domain 3 137 1.8E-44 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS10985 0f27549dc73d94f695e0b2493b1ff444 184 SUPERFAMILY SSF53041 2 137 6.8E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 SUPERFAMILY SSF46689 140 181 1.25E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 Gene3D G3DSA:1.20.5.40 107 132 1.2E-16 T 29-03-2018 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 Gene3D G3DSA:3.40.50.1390 1 106 2.2E-33 T 29-03-2018 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 Gene3D G3DSA:1.10.10.60 133 184 6.4E-11 T 29-03-2018 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 SMART SM00857 2 138 5.8E-58 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 Pfam PF02796 Helix-turn-helix domain of resolvase 140 183 2.4E-14 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 Pfam PF00239 Resolvase, N terminal domain 3 137 1.8E-44 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS11065 0f27549dc73d94f695e0b2493b1ff444 184 SUPERFAMILY SSF53041 2 137 6.8E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 Gene3D G3DSA:2.30.24.10 1 54 1.8E-20 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 Pfam PF03123 CAT RNA binding domain 3 57 2.2E-18 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 Pfam PF00874 PRD domain 182 275 1.0E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 Pfam PF00874 PRD domain 78 163 7.9E-17 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 SUPERFAMILY SSF63520 198 276 4.05E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 SUPERFAMILY SSF63520 56 164 9.16E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 SUPERFAMILY SSF50151 2 54 4.84E-14 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 SMART SM01061 2 60 1.7E-24 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 Gene3D G3DSA:1.10.1790.10 55 166 2.6E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS05980 99872319fc0cf754c1e1d65f92b66719 277 Gene3D G3DSA:1.10.1790.10 169 277 1.4E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS09945 b2d5674594480abb3fb77ad1937eacd8 100 Gene3D G3DSA:3.30.1330.30 4 100 1.3E-15 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SPSF3K_RS09945 b2d5674594480abb3fb77ad1937eacd8 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 6 95 1.1E-13 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 SPSF3K_RS09945 b2d5674594480abb3fb77ad1937eacd8 100 SUPERFAMILY SSF55315 6 99 5.15E-23 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 Gene3D G3DSA:3.40.50.300 308 570 3.1E-44 T 29-03-2018 SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 TIGRFAM TIGR04291 arsen_driv_ArsA: arsenical pump-driving ATPase 11 568 1.2E-251 T 29-03-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 Gene3D G3DSA:3.40.50.300 10 297 2.9E-54 T 29-03-2018 SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 SUPERFAMILY SSF52540 309 544 3.63E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 SMART SM00382 11 232 3.1 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 SMART SM00382 324 518 0.23 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 PIRSF PIRSF001327 1 571 4.0E-258 T 29-03-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 Pfam PF02374 Anion-transporting ATPase 326 467 8.0E-27 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 Pfam PF02374 Anion-transporting ATPase 12 294 9.4E-73 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 Pfam PF02374 Anion-transporting ATPase 474 555 2.2E-7 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 SUPERFAMILY SSF52540 13 293 2.57E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05715 5bf2e679976d93ffbef05c9918247de5 571 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 16 295 1.1E-72 T 29-03-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 SPSF3K_RS04450 a90f872a6834b0669b523db7bef2b20a 408 SUPERFAMILY SSF55729 301 396 1.13E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS04450 a90f872a6834b0669b523db7bef2b20a 408 SUPERFAMILY SSF55729 174 244 1.13E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS04450 a90f872a6834b0669b523db7bef2b20a 408 Gene3D G3DSA:3.40.630.30 180 376 6.5E-24 T 29-03-2018 SPSF3K_RS04450 a90f872a6834b0669b523db7bef2b20a 408 Pfam PF02388 FemAB family 8 391 2.9E-109 T 29-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 SPSF3K_RS04450 a90f872a6834b0669b523db7bef2b20a 408 Gene3D G3DSA:3.40.630.30 1 179 1.9E-36 T 29-03-2018 SPSF3K_RS04450 a90f872a6834b0669b523db7bef2b20a 408 SUPERFAMILY SSF55729 5 167 1.27E-42 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS01890 60fb86db981ed82bb06293f355495bd3 283 PIRSF PIRSF010376 2 283 2.9E-92 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SPSF3K_RS01890 60fb86db981ed82bb06293f355495bd3 283 SUPERFAMILY SSF55060 165 282 5.18E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS01890 60fb86db981ed82bb06293f355495bd3 283 Gene3D G3DSA:3.30.230.10 5 160 3.3E-47 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS01890 60fb86db981ed82bb06293f355495bd3 283 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 4 280 33.728 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SPSF3K_RS01890 60fb86db981ed82bb06293f355495bd3 283 Pfam PF00288 GHMP kinases N terminal domain 88 145 1.2E-11 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SPSF3K_RS01890 60fb86db981ed82bb06293f355495bd3 283 SUPERFAMILY SSF54211 4 156 4.25E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS01890 60fb86db981ed82bb06293f355495bd3 283 Gene3D G3DSA:3.30.70.890 164 283 3.8E-24 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS01890 60fb86db981ed82bb06293f355495bd3 283 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 4 283 5.2E-82 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 SPSF3K_RS01890 60fb86db981ed82bb06293f355495bd3 283 Pfam PF08544 GHMP kinases C terminal 201 273 1.1E-7 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS07195 9f0c7f51e2efe2c13dc87e5f26bbd2fa 764 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 270 6.5E-81 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 SPSF3K_RS07195 9f0c7f51e2efe2c13dc87e5f26bbd2fa 764 Gene3D G3DSA:3.40.50.300 280 383 7.9E-28 T 29-03-2018 SPSF3K_RS07195 9f0c7f51e2efe2c13dc87e5f26bbd2fa 764 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 4 761 0.0 T 29-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 SPSF3K_RS07195 9f0c7f51e2efe2c13dc87e5f26bbd2fa 764 Gene3D G3DSA:3.40.50.300 150 279 5.9E-35 T 29-03-2018 SPSF3K_RS07195 9f0c7f51e2efe2c13dc87e5f26bbd2fa 764 Gene3D G3DSA:3.40.50.300 1 149 2.0E-25 T 29-03-2018 SPSF3K_RS07195 9f0c7f51e2efe2c13dc87e5f26bbd2fa 764 SUPERFAMILY SSF52540 3 644 4.52E-172 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07195 9f0c7f51e2efe2c13dc87e5f26bbd2fa 764 Gene3D G3DSA:3.40.50.300 384 694 1.4E-49 T 29-03-2018 SPSF3K_RS07195 9f0c7f51e2efe2c13dc87e5f26bbd2fa 764 Pfam PF13361 UvrD-like helicase C-terminal domain 276 619 2.2E-76 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 Gene3D G3DSA:3.30.420.40 147 294 1.1E-14 T 29-03-2018 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 332 58.56 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 314 2.0E-127 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 4.3E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 4.3E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 4.3E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 4.3E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 156 177 4.3E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 266 275 4.3E-48 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 307 3.3E-104 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 Gene3D G3DSA:3.30.420.40 4 146 4.1E-40 T 29-03-2018 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 SUPERFAMILY SSF53067 5 309 1.38E-37 T 29-03-2018 SPSF3K_RS01275 294f20be122c6eeabee84b88fb8589f8 337 Pfam PF00814 Glycoprotease family 26 307 1.1E-100 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS05105 fbb89df7aeacf33687eb9568b180614e 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 216 6.1E-74 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SPSF3K_RS05105 fbb89df7aeacf33687eb9568b180614e 226 Pfam PF02224 Cytidylate kinase 6 220 6.7E-74 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SPSF3K_RS05105 fbb89df7aeacf33687eb9568b180614e 226 Hamap MF_00238 Cytidylate kinase [cmk]. 4 223 33.216 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 SPSF3K_RS05105 fbb89df7aeacf33687eb9568b180614e 226 Gene3D G3DSA:3.40.50.300 1 223 2.9E-53 T 29-03-2018 SPSF3K_RS05105 fbb89df7aeacf33687eb9568b180614e 226 SUPERFAMILY SSF52540 1 220 3.22E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09470 c99f0a2cd454d111717bcc0fbadc4b1f 438 Pfam PF01814 Hemerythrin HHE cation binding domain 88 222 6.8E-21 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 SPSF3K_RS09470 c99f0a2cd454d111717bcc0fbadc4b1f 438 Pfam PF13596 PAS domain 316 425 1.2E-27 T 29-03-2018 SPSF3K_RS09470 c99f0a2cd454d111717bcc0fbadc4b1f 438 Pfam PF04282 Family of unknown function (DUF438) 9 76 1.8E-22 T 29-03-2018 IPR007380 Domain of unknown function DUF438 SPSF3K_RS09470 c99f0a2cd454d111717bcc0fbadc4b1f 438 Gene3D G3DSA:3.30.450.20 320 432 4.1E-9 T 29-03-2018 SPSF3K_RS09470 c99f0a2cd454d111717bcc0fbadc4b1f 438 Gene3D G3DSA:1.20.120.520 80 319 2.3E-53 T 29-03-2018 SPSF3K_RS00450 82be4331a54a12e4028cb469313aab46 381 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 69 124 5.9E-19 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPSF3K_RS00450 82be4331a54a12e4028cb469313aab46 381 Gene3D G3DSA:1.10.150.130 63 172 2.5E-18 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SPSF3K_RS00450 82be4331a54a12e4028cb469313aab46 381 Pfam PF00589 Phage integrase family 175 364 3.8E-29 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS00450 82be4331a54a12e4028cb469313aab46 381 Gene3D G3DSA:1.10.443.10 173 380 1.7E-39 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS00450 82be4331a54a12e4028cb469313aab46 381 SUPERFAMILY SSF56349 69 371 3.24E-66 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPSF3K_RS01565 b49e876159e2e776a05b3ddbd75ef4c6 775 ProSitePatterns PS00850 Glycine radical domain signature. 733 741 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site SPSF3K_RS01565 b49e876159e2e776a05b3ddbd75ef4c6 775 SUPERFAMILY SSF51998 9 762 1.05E-201 T 29-03-2018 SPSF3K_RS01565 b49e876159e2e776a05b3ddbd75ef4c6 775 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 14 763 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 SPSF3K_RS01565 b49e876159e2e776a05b3ddbd75ef4c6 775 PIRSF PIRSF000379 11 763 2.7E-291 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 SPSF3K_RS01565 b49e876159e2e776a05b3ddbd75ef4c6 775 Pfam PF01228 Glycine radical 642 742 2.8E-23 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 SPSF3K_RS01565 b49e876159e2e776a05b3ddbd75ef4c6 775 Pfam PF02901 Pyruvate formate lyase-like 30 613 1.6E-149 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 SPSF3K_RS01565 b49e876159e2e776a05b3ddbd75ef4c6 775 Gene3D G3DSA:3.20.70.20 5 763 1.5E-198 T 29-03-2018 SPSF3K_RS07085 98a79bb6c6bc91cf839ae4e2c063b89e 252 Gene3D G3DSA:3.30.540.10 1 149 1.4E-29 T 29-03-2018 SPSF3K_RS07085 98a79bb6c6bc91cf839ae4e2c063b89e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 5.1E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SPSF3K_RS07085 98a79bb6c6bc91cf839ae4e2c063b89e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 5.1E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SPSF3K_RS07085 98a79bb6c6bc91cf839ae4e2c063b89e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 171 192 5.1E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SPSF3K_RS07085 98a79bb6c6bc91cf839ae4e2c063b89e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 201 225 5.1E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SPSF3K_RS07085 98a79bb6c6bc91cf839ae4e2c063b89e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 5.1E-17 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SPSF3K_RS07085 98a79bb6c6bc91cf839ae4e2c063b89e 252 Gene3D G3DSA:3.40.190.80 150 251 6.8E-10 T 29-03-2018 SPSF3K_RS07085 98a79bb6c6bc91cf839ae4e2c063b89e 252 Pfam PF00459 Inositol monophosphatase family 7 233 8.0E-34 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 SPSF3K_RS07085 98a79bb6c6bc91cf839ae4e2c063b89e 252 SUPERFAMILY SSF56655 5 237 1.83E-51 T 29-03-2018 SPSF3K_RS02205 0a04cba10d203b5711dc612ff4e90926 295 SUPERFAMILY SSF161098 55 284 3.66E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS02205 0a04cba10d203b5711dc612ff4e90926 295 Gene3D G3DSA:1.10.3720.10 3 287 7.1E-38 T 29-03-2018 SPSF3K_RS02205 0a04cba10d203b5711dc612ff4e90926 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 294 2.7E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 396 420 1.8E-7 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 SMART SM00278 531 550 110.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 SMART SM00278 467 486 0.18 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 SMART SM00278 433 452 20.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 PIRSF PIRSF001604 1 654 2.1E-241 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 SMART SM00292 580 654 1.6E-8 T 29-03-2018 IPR001357 BRCT domain SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Gene3D G3DSA:1.10.287.610 1 64 2.5E-21 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Pfam PF12826 Helix-hairpin-helix motif 497 557 1.2E-18 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 319 334 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Gene3D G3DSA:3.30.1490.70 78 163 2.4E-19 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 310 386 5.5E-35 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 SMART SM00532 2 435 1.0E-232 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 8 648 1.2E-241 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 306 1.8E-114 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 SUPERFAMILY SSF52113 582 652 6.17E-19 T 29-03-2018 IPR001357 BRCT domain SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Gene3D G3DSA:1.10.150.20 491 541 5.6E-19 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 585 652 4.0E-13 T 29-03-2018 IPR001357 BRCT domain SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Gene3D G3DSA:3.30.1490.70 191 309 7.3E-24 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Hamap MF_01588 DNA ligase [ligA]. 1 654 48.593 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 SUPERFAMILY SSF56091 2 306 2.24E-110 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 SUPERFAMILY SSF50249 306 388 5.65E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 109 138 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Gene3D G3DSA:2.40.50.140 310 378 1.4E-33 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Gene3D G3DSA:1.10.150.20 542 600 0.0021 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Pfam PF14520 Helix-hairpin-helix domain 435 485 2.7E-9 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Gene3D G3DSA:1.10.150.20 419 490 6.8E-24 T 29-03-2018 SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 Gene3D G3DSA:3.40.50.10190 601 653 1.6E-18 T 29-03-2018 IPR001357 BRCT domain SPSF3K_RS04835 7db3c26311995676a907c775d5a33e5f 654 SUPERFAMILY SSF47781 392 572 5.56E-55 T 29-03-2018 IPR010994 RuvA domain 2-like SPSF3K_RS07405 17d87c62e945da7fa20b028e0285bca1 622 Pfam PF03354 Phage Terminase 102 582 3.9E-48 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 2.8E-35 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 PRINTS PR00834 HtrA/DegQ protease family signature 248 265 2.8E-35 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 PRINTS PR00834 HtrA/DegQ protease family signature 342 354 2.8E-35 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 PRINTS PR00834 HtrA/DegQ protease family signature 122 134 2.8E-35 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 PRINTS PR00834 HtrA/DegQ protease family signature 184 208 2.8E-35 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 PRINTS PR00834 HtrA/DegQ protease family signature 143 163 2.8E-35 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 Pfam PF13180 PDZ domain 298 393 9.1E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 Gene3D G3DSA:2.40.10.10 164 288 1.6E-32 T 29-03-2018 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 Pfam PF13365 Trypsin-like peptidase domain 110 255 1.8E-28 T 29-03-2018 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 SMART SM00228 298 384 2.7E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 Gene3D G3DSA:2.30.42.10 298 402 1.7E-24 T 29-03-2018 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 SUPERFAMILY SSF50494 58 290 2.24E-54 T 29-03-2018 IPR009003 Peptidase S1, PA clan SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 SUPERFAMILY SSF50156 284 393 1.73E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SPSF3K_RS00010 8afe939fa011e966ce1fa7b968d4433a 402 Gene3D G3DSA:2.40.10.10 54 163 4.2E-25 T 29-03-2018 SPSF3K_RS09060 687e83541fea64002dfd2d236dfb36f9 443 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 10 437 2.0E-136 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 SPSF3K_RS09060 687e83541fea64002dfd2d236dfb36f9 443 SUPERFAMILY SSF55031 184 356 2.58E-31 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SPSF3K_RS09060 687e83541fea64002dfd2d236dfb36f9 443 Gene3D G3DSA:3.30.70.360 257 349 6.6E-17 T 29-03-2018 SPSF3K_RS09060 687e83541fea64002dfd2d236dfb36f9 443 SUPERFAMILY SSF53187 360 441 8.0E-58 T 29-03-2018 SPSF3K_RS09060 687e83541fea64002dfd2d236dfb36f9 443 SUPERFAMILY SSF53187 7 184 8.0E-58 T 29-03-2018 SPSF3K_RS09060 687e83541fea64002dfd2d236dfb36f9 443 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 114 152 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPSF3K_RS09060 687e83541fea64002dfd2d236dfb36f9 443 Pfam PF01546 Peptidase family M20/M25/M40 81 438 1.6E-29 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SPSF3K_RS09060 687e83541fea64002dfd2d236dfb36f9 443 Gene3D G3DSA:3.40.630.10 2 191 2.0E-26 T 29-03-2018 SPSF3K_RS02745 5a140fc0a5787f136ee870e03f0937c6 75 Gene3D G3DSA:3.30.70.100 1 71 5.1E-15 T 29-03-2018 SPSF3K_RS02745 5a140fc0a5787f136ee870e03f0937c6 75 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SPSF3K_RS02745 5a140fc0a5787f136ee870e03f0937c6 75 SUPERFAMILY SSF55008 1 71 8.51E-14 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS02745 5a140fc0a5787f136ee870e03f0937c6 75 Pfam PF00403 Heavy-metal-associated domain 6 68 8.2E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS01460 c2893717493cfef00600328666e72f5e 185 TIGRFAM TIGR03124 citrate_citX: holo-ACP synthase CitX 13 176 2.3E-51 T 29-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 SPSF3K_RS01460 c2893717493cfef00600328666e72f5e 185 Pfam PF03802 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 14 176 1.1E-49 T 29-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 SPSF3K_RS09095 e51c3d36462139590310b567c81ff47e 234 Pfam PF03483 B3/4 domain 74 203 6.0E-23 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SPSF3K_RS09095 e51c3d36462139590310b567c81ff47e 234 SUPERFAMILY SSF56037 51 205 4.71E-30 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SPSF3K_RS09095 e51c3d36462139590310b567c81ff47e 234 SMART SM00873 65 213 4.6E-10 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SPSF3K_RS09095 e51c3d36462139590310b567c81ff47e 234 Gene3D G3DSA:3.50.40.10 49 215 8.1E-28 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 Pfam PF00483 Nucleotidyl transferase 7 258 3.9E-65 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 SUPERFAMILY SSF53448 340 355 1.87E-81 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 SUPERFAMILY SSF53448 2 262 1.87E-81 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 Gene3D G3DSA:3.90.550.10 1 265 1.0E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 SUPERFAMILY SSF51161 268 361 4.12E-15 T 29-03-2018 IPR011004 Trimeric LpxA-like SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 5 358 4.1E-144 T 29-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 11 30 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 Gene3D G3DSA:2.160.10.10 266 373 1.0E-15 T 29-03-2018 SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 2 373 46.606 T 29-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SPSF3K_RS04860 1983c1a1fd8b059aed4051da52d0fb7f 379 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 189 199 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 SPSF3K_RS06820 3ba57972d110528e743a73e6963c6407 250 SMART SM00382 33 220 1.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS06820 3ba57972d110528e743a73e6963c6407 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS06820 3ba57972d110528e743a73e6963c6407 250 Gene3D G3DSA:3.40.50.300 1 232 5.4E-64 T 29-03-2018 SPSF3K_RS06820 3ba57972d110528e743a73e6963c6407 250 SUPERFAMILY SSF52540 2 226 3.99E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06820 3ba57972d110528e743a73e6963c6407 250 Pfam PF00005 ABC transporter 24 173 6.3E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00385 47d12f813603f3ab8637c8175d76c992 140 Gene3D G3DSA:3.30.50.10 2 55 2.7E-5 T 29-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 SPSF3K_RS02640 4962b6227c81f8fed456a5eb1cc4de73 194 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 149 1.7E-4 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS02640 4962b6227c81f8fed456a5eb1cc4de73 194 Gene3D G3DSA:2.160.10.10 61 193 2.5E-30 T 29-03-2018 SPSF3K_RS02640 4962b6227c81f8fed456a5eb1cc4de73 194 SUPERFAMILY SSF51161 7 175 1.8E-50 T 29-03-2018 IPR011004 Trimeric LpxA-like SPSF3K_RS02640 4962b6227c81f8fed456a5eb1cc4de73 194 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 165 3.8E-68 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 SPSF3K_RS02640 4962b6227c81f8fed456a5eb1cc4de73 194 Gene3D G3DSA:1.10.3130.10 3 60 1.1E-20 T 29-03-2018 SPSF3K_RS02640 4962b6227c81f8fed456a5eb1cc4de73 194 PIRSF PIRSF000441 2 193 1.9E-68 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 SPSF3K_RS07090 c584fae90a2432150a0040d755bc9fab 92 PIRSF PIRSF037260 1 92 2.2E-39 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 SPSF3K_RS07090 c584fae90a2432150a0040d755bc9fab 92 Gene3D G3DSA:1.10.220.80 14 90 3.8E-31 T 29-03-2018 IPR023324 BH2638-like domain SPSF3K_RS07090 c584fae90a2432150a0040d755bc9fab 92 Hamap MF_01041 UPF0223 protein . 3 90 24.681 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 SPSF3K_RS07090 c584fae90a2432150a0040d755bc9fab 92 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 4 81 2.0E-26 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 SPSF3K_RS07090 c584fae90a2432150a0040d755bc9fab 92 SUPERFAMILY SSF158504 6 89 4.32E-33 T 29-03-2018 IPR023324 BH2638-like domain SPSF3K_RS07090 c584fae90a2432150a0040d755bc9fab 92 Pfam PF05256 Uncharacterised protein family (UPF0223) 4 86 1.4E-35 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 SPSF3K_RS01450 2c749d97892a6bc3cd48329096852d7b 295 PIRSF PIRSF015582 1 294 5.8E-84 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like SPSF3K_RS01450 2c749d97892a6bc3cd48329096852d7b 295 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 6 224 3.6E-83 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SPSF3K_RS01450 2c749d97892a6bc3cd48329096852d7b 295 SUPERFAMILY SSF51621 2 234 1.99E-65 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPSF3K_RS01450 2c749d97892a6bc3cd48329096852d7b 295 TIGRFAM TIGR01588 citE: citrate (pro-3S)-lyase, beta subunit 3 289 1.4E-143 T 29-03-2018 IPR006475 Citrate lyase, beta subunit, bacteria GO:0005737|GO:0006084|GO:0008816|GO:0009346 KEGG: 00720+4.1.3.34|MetaCyc: PWY-5392|MetaCyc: PWY-6038 SPSF3K_RS01450 2c749d97892a6bc3cd48329096852d7b 295 Gene3D G3DSA:3.20.20.360 2 263 1.3E-54 T 29-03-2018 SPSF3K_RS03900 8e1989dea3a50f918cd9cc0fc88895b6 135 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 76 87 - T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 SPSF3K_RS03900 8e1989dea3a50f918cd9cc0fc88895b6 135 Gene3D G3DSA:1.10.3830.10 13 126 1.5E-36 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 SPSF3K_RS03900 8e1989dea3a50f918cd9cc0fc88895b6 135 Pfam PF01219 Prokaryotic diacylglycerol kinase 23 124 4.9E-32 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 SPSF3K_RS01105 c313f8463ffba6b821ec0d29691039a0 270 Pfam PF01380 SIS domain 125 210 2.4E-17 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS01105 c313f8463ffba6b821ec0d29691039a0 270 SUPERFAMILY SSF53697 91 255 1.48E-30 T 29-03-2018 SPSF3K_RS01105 c313f8463ffba6b821ec0d29691039a0 270 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 73 4.1E-8 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SPSF3K_RS01105 c313f8463ffba6b821ec0d29691039a0 270 Gene3D G3DSA:3.40.50.10490 118 253 6.8E-25 T 29-03-2018 SPSF3K_RS01105 c313f8463ffba6b821ec0d29691039a0 270 Gene3D G3DSA:1.10.10.10 4 117 4.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01105 c313f8463ffba6b821ec0d29691039a0 270 SUPERFAMILY SSF46689 7 79 2.33E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS06355 f866224c9deae435b143eaffadef13b2 61 SUPERFAMILY SSF55331 2 57 6.28E-17 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily SPSF3K_RS06355 f866224c9deae435b143eaffadef13b2 61 Pfam PF01361 Tautomerase enzyme 2 58 5.2E-22 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 SPSF3K_RS06355 f866224c9deae435b143eaffadef13b2 61 Gene3D G3DSA:3.30.429.10 1 57 1.6E-16 T 29-03-2018 SPSF3K_RS05200 bdd6e40bf2650bc14b3ef20cea1d0b45 148 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 92 107 3.6E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SPSF3K_RS05200 bdd6e40bf2650bc14b3ef20cea1d0b45 148 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 126 142 3.6E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SPSF3K_RS05200 bdd6e40bf2650bc14b3ef20cea1d0b45 148 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 48 56 3.6E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SPSF3K_RS05200 bdd6e40bf2650bc14b3ef20cea1d0b45 148 TIGRFAM TIGR00077 lspA: signal peptidase II 6 142 1.3E-39 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SPSF3K_RS05200 bdd6e40bf2650bc14b3ef20cea1d0b45 148 Pfam PF01252 Signal peptidase (SPase) II 11 144 1.3E-39 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SPSF3K_RS05200 bdd6e40bf2650bc14b3ef20cea1d0b45 148 ProSitePatterns PS00855 Signal peptidases II signature. 95 107 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SPSF3K_RS05200 bdd6e40bf2650bc14b3ef20cea1d0b45 148 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 148 15.599 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 SPSF3K_RS05005 13f9bf6a8dc89e86ae6eae2bfb35e743 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 2.4E-7 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPSF3K_RS05005 13f9bf6a8dc89e86ae6eae2bfb35e743 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.4E-7 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPSF3K_RS05005 13f9bf6a8dc89e86ae6eae2bfb35e743 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 2.4E-7 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPSF3K_RS05005 13f9bf6a8dc89e86ae6eae2bfb35e743 126 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 123 7.9E-32 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPSF3K_RS05005 13f9bf6a8dc89e86ae6eae2bfb35e743 126 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 29-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site SPSF3K_RS05005 13f9bf6a8dc89e86ae6eae2bfb35e743 126 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 121 4.3E-33 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPSF3K_RS05005 13f9bf6a8dc89e86ae6eae2bfb35e743 126 SUPERFAMILY SSF81330 10 118 1.57E-25 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPSF3K_RS03365 418f3508442e4978ceb5d1d981065db3 241 Gene3D G3DSA:3.30.2350.10 69 241 2.9E-41 T 29-03-2018 SPSF3K_RS03365 418f3508442e4978ceb5d1d981065db3 241 Pfam PF01479 S4 domain 1 47 1.3E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS03365 418f3508442e4978ceb5d1d981065db3 241 SMART SM00363 1 64 2.4E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS03365 418f3508442e4978ceb5d1d981065db3 241 SUPERFAMILY SSF55120 45 234 1.15E-45 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS03365 418f3508442e4978ceb5d1d981065db3 241 SUPERFAMILY SSF55174 1 55 3.14E-16 T 29-03-2018 SPSF3K_RS03365 418f3508442e4978ceb5d1d981065db3 241 Gene3D G3DSA:3.10.290.10 1 68 1.1E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS03365 418f3508442e4978ceb5d1d981065db3 241 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPSF3K_RS03365 418f3508442e4978ceb5d1d981065db3 241 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 225 2.3E-47 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPSF3K_RS03365 418f3508442e4978ceb5d1d981065db3 241 Pfam PF00849 RNA pseudouridylate synthase 61 194 3.8E-22 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS03140 30610f5d765b15d3065a9f58ddbdedf5 196 SMART SM00471 22 149 4.9E-6 T 29-03-2018 IPR003607 HD/PDEase domain SPSF3K_RS03140 30610f5d765b15d3065a9f58ddbdedf5 196 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 20 188 4.2E-45 T 29-03-2018 IPR005249 Conserved hypothetical protein CHP00488 SPSF3K_RS03140 30610f5d765b15d3065a9f58ddbdedf5 196 Pfam PF01966 HD domain 26 138 3.3E-12 T 29-03-2018 IPR006674 HD domain SPSF3K_RS03140 30610f5d765b15d3065a9f58ddbdedf5 196 SUPERFAMILY SSF109604 6 192 1.83E-32 T 29-03-2018 SPSF3K_RS03140 30610f5d765b15d3065a9f58ddbdedf5 196 TIGRFAM TIGR00277 HDIG: HDIG domain 26 101 6.2E-8 T 29-03-2018 IPR006675 HDIG domain SPSF3K_RS03140 30610f5d765b15d3065a9f58ddbdedf5 196 Gene3D G3DSA:1.10.3210.10 8 194 3.6E-24 T 29-03-2018 SPSF3K_RS05025 7be9bad8cdc29671c90bb58c389ea5e3 283 SUPERFAMILY SSF51735 2 280 1.0E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS05025 7be9bad8cdc29671c90bb58c389ea5e3 283 Gene3D G3DSA:3.90.25.10 199 267 1.5E-19 T 29-03-2018 SPSF3K_RS05025 7be9bad8cdc29671c90bb58c389ea5e3 283 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 279 1.1E-82 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 SPSF3K_RS05025 7be9bad8cdc29671c90bb58c389ea5e3 283 Pfam PF04321 RmlD substrate binding domain 2 280 2.6E-106 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 SPSF3K_RS05025 7be9bad8cdc29671c90bb58c389ea5e3 283 Gene3D G3DSA:3.40.50.720 1 198 7.1E-30 T 29-03-2018 SPSF3K_RS05455 a98e13ca43d41d5198f8a8fe2de5edd6 199 Gene3D G3DSA:3.40.50.300 2 199 1.3E-31 T 29-03-2018 SPSF3K_RS05455 a98e13ca43d41d5198f8a8fe2de5edd6 199 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 30 195 1.4E-12 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS05455 a98e13ca43d41d5198f8a8fe2de5edd6 199 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 17 199 29.102 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 SPSF3K_RS05455 a98e13ca43d41d5198f8a8fe2de5edd6 199 PRINTS PR00449 Transforming protein P21 ras signature 139 152 7.4E-5 T 29-03-2018 SPSF3K_RS05455 a98e13ca43d41d5198f8a8fe2de5edd6 199 PRINTS PR00449 Transforming protein P21 ras signature 30 51 7.4E-5 T 29-03-2018 SPSF3K_RS05455 a98e13ca43d41d5198f8a8fe2de5edd6 199 PRINTS PR00449 Transforming protein P21 ras signature 177 199 7.4E-5 T 29-03-2018 SPSF3K_RS05455 a98e13ca43d41d5198f8a8fe2de5edd6 199 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 13 195 1.0E-73 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 SPSF3K_RS05455 a98e13ca43d41d5198f8a8fe2de5edd6 199 SUPERFAMILY SSF52540 22 199 1.25E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05455 a98e13ca43d41d5198f8a8fe2de5edd6 199 Pfam PF01926 50S ribosome-binding GTPase 31 149 1.1E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 497 1.3E-226 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Pfam PF07516 SecA Wing and Scaffold domain 571 779 5.6E-54 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Gene3D G3DSA:3.40.50.300 398 586 1.7E-51 T 29-03-2018 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 SUPERFAMILY SSF52540 397 567 2.49E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 SMART SM00957 5 383 4.5E-262 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 SMART SM00958 227 339 2.2E-57 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 PRINTS PR00906 SecA protein signature 115 125 5.6E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 PRINTS PR00906 SecA protein signature 168 188 5.6E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 PRINTS PR00906 SecA protein signature 357 374 5.6E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 PRINTS PR00906 SecA protein signature 61 85 5.6E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 PRINTS PR00906 SecA protein signature 99 113 5.6E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 PRINTS PR00906 SecA protein signature 394 407 5.6E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 PRINTS PR00906 SecA protein signature 320 342 5.6E-70 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Pfam PF02810 SEC-C motif 821 839 7.8E-9 T 29-03-2018 IPR004027 SEC-C motif SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Gene3D G3DSA:1.10.3060.10 587 694 4.9E-24 T 29-03-2018 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Gene3D G3DSA:1.10.3060.10 695 791 1.4E-21 T 29-03-2018 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 SUPERFAMILY SSF81886 573 790 4.58E-68 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 SUPERFAMILY SSF81886 817 829 4.58E-68 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 ProSitePatterns PS01312 SecA family signature. 481 496 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Pfam PF07517 SecA DEAD-like domain 9 383 2.3E-122 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 SUPERFAMILY SSF81767 231 349 4.58E-41 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 SUPERFAMILY SSF52540 349 396 1.34E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 SUPERFAMILY SSF52540 12 226 1.34E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 782 19.077 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Pfam PF01043 SecA preprotein cross-linking domain 231 339 9.9E-35 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Gene3D G3DSA:3.40.50.300 292 397 1.2E-7 T 29-03-2018 SPSF3K_RS01725 97e5eb6e16f876502e575822dbaf1334 842 Gene3D G3DSA:3.40.50.300 8 268 3.6E-46 T 29-03-2018 SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 SUPERFAMILY SSF47384 207 282 1.0E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 SMART SM00387 326 434 3.4E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 Gene3D G3DSA:1.10.287.130 207 279 7.6E-10 T 29-03-2018 SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 434 3.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 SMART SM00388 216 283 1.8E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 SUPERFAMILY SSF55874 294 434 5.89E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 2.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 391 2.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 2.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 434 2.7E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 283 1.3E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPSF3K_RS07040 635356ee60d04c936b36281325eb123c 434 Gene3D G3DSA:3.30.565.10 281 434 8.4E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS06240 ac25a51c0d7b208d59ff51759fdb03ca 214 SMART SM00881 80 183 2.9E-16 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SPSF3K_RS06240 ac25a51c0d7b208d59ff51759fdb03ca 214 SUPERFAMILY SSF51735 83 210 3.08E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06240 ac25a51c0d7b208d59ff51759fdb03ca 214 SUPERFAMILY SSF46785 8 79 3.45E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06240 ac25a51c0d7b208d59ff51759fdb03ca 214 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 212 38.311 T 29-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 SPSF3K_RS06240 ac25a51c0d7b208d59ff51759fdb03ca 214 Gene3D G3DSA:1.10.10.10 5 72 2.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06240 ac25a51c0d7b208d59ff51759fdb03ca 214 Gene3D G3DSA:3.40.50.720 73 190 1.7E-17 T 29-03-2018 SPSF3K_RS06240 ac25a51c0d7b208d59ff51759fdb03ca 214 Pfam PF02629 CoA binding domain 83 182 1.6E-23 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SPSF3K_RS06240 ac25a51c0d7b208d59ff51759fdb03ca 214 Pfam PF06971 Putative DNA-binding protein N-terminus 7 54 3.1E-17 T 29-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 SPSF3K_RS06460 b12d310d4e66da654379fa09e7abda98 142 SUPERFAMILY SSF47413 81 141 2.53E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS06460 b12d310d4e66da654379fa09e7abda98 142 Pfam PF01381 Helix-turn-helix 87 138 1.0E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS06460 b12d310d4e66da654379fa09e7abda98 142 Gene3D G3DSA:1.10.260.40 70 142 3.3E-12 T 29-03-2018 SPSF3K_RS06460 b12d310d4e66da654379fa09e7abda98 142 SMART SM00530 83 138 6.0E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS04805 cd01b3eb98f11b14c675267af42344e2 459 Gene3D G3DSA:1.10.1140.10 360 459 5.2E-17 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04805 cd01b3eb98f11b14c675267af42344e2 459 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 10 76 9.0E-14 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04805 cd01b3eb98f11b14c675267af42344e2 459 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 133 351 2.7E-67 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04805 cd01b3eb98f11b14c675267af42344e2 459 SUPERFAMILY SSF52540 80 355 2.66E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04805 cd01b3eb98f11b14c675267af42344e2 459 PIRSF PIRSF039114 1 459 2.4E-246 T 29-03-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04805 cd01b3eb98f11b14c675267af42344e2 459 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04805 cd01b3eb98f11b14c675267af42344e2 459 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 4 459 58.905 T 29-03-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04805 cd01b3eb98f11b14c675267af42344e2 459 Gene3D G3DSA:3.40.50.300 25 351 2.7E-86 T 29-03-2018 SPSF3K_RS01155 67624266d2556f53b043495a690f795f 220 PIRSF PIRSF001461 1 220 6.1E-89 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SPSF3K_RS01155 67624266d2556f53b043495a690f795f 220 SUPERFAMILY SSF51366 4 217 1.1E-71 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SPSF3K_RS01155 67624266d2556f53b043495a690f795f 220 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 215 9.2E-83 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SPSF3K_RS01155 67624266d2556f53b043495a690f795f 220 Gene3D G3DSA:3.20.20.70 1 219 5.4E-85 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS01155 67624266d2556f53b043495a690f795f 220 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 202 2.7E-77 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SPSF3K_RS01155 67624266d2556f53b043495a690f795f 220 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SPSF3K_RS01155 67624266d2556f53b043495a690f795f 220 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 SPSF3K_RS09250 9c4ac3018caf2e9da43d298e7134ab8b 287 Gene3D G3DSA:1.10.260.40 1 141 2.8E-12 T 29-03-2018 SPSF3K_RS09250 9c4ac3018caf2e9da43d298e7134ab8b 287 SMART SM00530 7 61 1.3E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS09250 9c4ac3018caf2e9da43d298e7134ab8b 287 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 63 284 1.6E-48 T 29-03-2018 IPR010057 Transcription activator MutR, C-terminal SPSF3K_RS09250 9c4ac3018caf2e9da43d298e7134ab8b 287 SUPERFAMILY SSF47413 3 63 2.95E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS09250 9c4ac3018caf2e9da43d298e7134ab8b 287 Pfam PF01381 Helix-turn-helix 9 61 7.5E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 SMART SM00838 598 685 4.5E-51 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 SUPERFAMILY SSF52540 6 280 8.01E-113 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Pfam PF14492 Elongation Factor G, domain II 402 475 5.7E-33 T 29-03-2018 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Gene3D G3DSA:3.30.70.870 400 489 1.3E-33 T 29-03-2018 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 SUPERFAMILY SSF54980 601 688 2.4E-29 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 SUPERFAMILY SSF50447 263 400 1.51E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 110.014 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 8.2E-43 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 4.0E-70 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 9.8E-13 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 SMART SM00889 478 596 1.1E-71 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Gene3D G3DSA:3.40.50.300 1 285 2.1E-66 T 29-03-2018 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Pfam PF03764 Elongation factor G, domain IV 477 596 3.3E-46 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Gene3D G3DSA:3.30.70.240 612 689 2.1E-31 T 29-03-2018 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 SUPERFAMILY SSF54980 400 478 8.99E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.3E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Gene3D G3DSA:2.40.30.10 287 399 9.3E-28 T 29-03-2018 SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Pfam PF00679 Elongation factor G C-terminus 599 684 2.8E-29 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 Gene3D G3DSA:3.30.230.10 490 611 1.8E-42 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS01200 eb14bd9357ca303c1c47b3dfabff9292 692 SUPERFAMILY SSF54211 477 597 1.37E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 SMART SM00662 18 225 6.6E-89 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 251 309 2.0E-26 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 35.865 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 Gene3D G3DSA:1.10.150.20 239 312 2.5E-24 T 29-03-2018 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 SUPERFAMILY SSF47789 245 311 3.4E-23 T 29-03-2018 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 18 310 2.1E-113 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 Gene3D G3DSA:3.30.1360.10 1 110 5.1E-20 T 29-03-2018 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 Gene3D G3DSA:3.30.1360.10 111 222 1.3E-20 T 29-03-2018 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 SUPERFAMILY SSF56553 48 169 1.31E-40 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 SUPERFAMILY SSF55257 4 48 1.94E-29 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 SUPERFAMILY SSF55257 170 224 1.94E-29 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 219 1.7E-20 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 238 302 1.8E-27 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS10390 36a740879ff0c6d59a7e4045bcd98a8e 312 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 150 4.7E-23 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS07865 d2a43f19e1f65e4d8a1e4d234d7d99d4 132 Pfam PF07883 Cupin domain 45 105 2.1E-6 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SPSF3K_RS07865 d2a43f19e1f65e4d8a1e4d234d7d99d4 132 SUPERFAMILY SSF51182 17 131 8.89E-22 T 29-03-2018 IPR011051 RmlC-like cupin domain SPSF3K_RS07865 d2a43f19e1f65e4d8a1e4d234d7d99d4 132 Gene3D G3DSA:2.60.120.10 14 132 2.6E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS07070 2c2150d0df7a1e8696b8cc0e2154d7c6 295 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 287 1.2E-76 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 SPSF3K_RS07070 2c2150d0df7a1e8696b8cc0e2154d7c6 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 292 7.2E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS07070 2c2150d0df7a1e8696b8cc0e2154d7c6 295 Gene3D G3DSA:1.10.3720.10 10 293 1.7E-37 T 29-03-2018 SPSF3K_RS07070 2c2150d0df7a1e8696b8cc0e2154d7c6 295 SUPERFAMILY SSF161098 16 276 3.01E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04240 69162d0d47aef1791021fd0522671a7b 217 PIRSF PIRSF003107 1 217 3.7E-53 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SPSF3K_RS04240 69162d0d47aef1791021fd0522671a7b 217 SUPERFAMILY SSF109755 2 216 7.53E-55 T 29-03-2018 SPSF3K_RS04240 69162d0d47aef1791021fd0522671a7b 217 Gene3D G3DSA:1.20.58.220 1 111 2.1E-21 T 29-03-2018 SPSF3K_RS04240 69162d0d47aef1791021fd0522671a7b 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 214 1.8E-65 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SPSF3K_RS04240 69162d0d47aef1791021fd0522671a7b 217 Pfam PF01895 PhoU domain 122 204 4.1E-16 T 29-03-2018 IPR026022 PhoU domain SPSF3K_RS04240 69162d0d47aef1791021fd0522671a7b 217 Pfam PF01895 PhoU domain 19 103 2.6E-17 T 29-03-2018 IPR026022 PhoU domain SPSF3K_RS04240 69162d0d47aef1791021fd0522671a7b 217 Gene3D G3DSA:1.20.58.220 112 217 1.2E-20 T 29-03-2018 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 SMART SM00354 1 55 2.9E-10 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 Pfam PF13377 Periplasmic binding protein-like domain 165 331 1.1E-28 T 29-03-2018 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 Gene3D G3DSA:1.10.260.40 2 61 3.4E-17 T 29-03-2018 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 8.8E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 Gene3D G3DSA:3.40.50.2300 173 308 1.6E-27 T 29-03-2018 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 SUPERFAMILY SSF53822 74 311 7.85E-39 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 Gene3D G3DSA:3.40.50.2300 62 172 3.6E-11 T 29-03-2018 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 SUPERFAMILY SSF47413 3 50 1.37E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.9E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02525 871a29e9737576c5536f94783fae3479 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.9E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 SUPERFAMILY SSF52540 40 87 1.73E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 SUPERFAMILY SSF52540 463 578 1.73E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 Gene3D G3DSA:3.40.50.300 15 419 5.7E-31 T 29-03-2018 SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 662 43.905 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 Gene3D G3DSA:4.10.860.10 606 662 2.6E-14 T 29-03-2018 IPR001943 UVR domain GO:0005515 SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 Pfam PF04851 Type III restriction enzyme, res subunit 17 143 3.9E-12 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 Gene3D G3DSA:3.40.50.300 420 593 1.0E-31 T 29-03-2018 SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 Pfam PF12344 Ultra-violet resistance protein B 556 598 7.9E-23 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 10 660 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 SMART SM00490 464 550 3.0E-20 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 SMART SM00487 14 430 3.6E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 Pfam PF00271 Helicase conserved C-terminal domain 442 549 4.1E-18 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 Pfam PF02151 UvrB/uvrC motif 627 660 1.2E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 SUPERFAMILY SSF46600 615 661 1.23E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 SPSF3K_RS08270 341a3b6fc4c05bd4d0815db664e0dc6a 663 SUPERFAMILY SSF52540 8 419 5.4E-140 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 112 126 7.2E-29 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 155 172 7.2E-29 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 11 18 7.2E-29 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 24 45 7.2E-29 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 81 98 7.2E-29 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 55 63 7.2E-29 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 5 254 28.627 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 SUPERFAMILY SSF53613 3 257 5.89E-47 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 Gene3D G3DSA:3.40.1190.20 1 260 9.4E-43 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 PIRSF PIRSF000513 1 261 5.1E-80 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS08590 4a69d9a458f3766cd733bcd57681115a 263 Pfam PF02110 Hydroxyethylthiazole kinase family 3 249 4.3E-71 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 SPSF3K_RS01885 091e5a05f950691e4ec2ee2192c375a3 326 Gene3D G3DSA:1.10.600.10 1 326 1.4E-81 T 29-03-2018 IPR008949 Isoprenoid synthase domain SPSF3K_RS01885 091e5a05f950691e4ec2ee2192c375a3 326 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 85 99 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SPSF3K_RS01885 091e5a05f950691e4ec2ee2192c375a3 326 Pfam PF00348 Polyprenyl synthetase 33 263 8.5E-58 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SPSF3K_RS01885 091e5a05f950691e4ec2ee2192c375a3 326 SUPERFAMILY SSF48576 2 325 1.66E-76 T 29-03-2018 IPR008949 Isoprenoid synthase domain SPSF3K_RS01885 091e5a05f950691e4ec2ee2192c375a3 326 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 208 220 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SPSF3K_RS10200 33a76932878861f6c7653a28895791d6 488 SUPERFAMILY SSF75304 1 481 1.7E-149 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPSF3K_RS10200 33a76932878861f6c7653a28895791d6 488 Pfam PF01425 Amidase 25 463 1.6E-144 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPSF3K_RS10200 33a76932878861f6c7653a28895791d6 488 Gene3D G3DSA:3.90.1300.10 2 483 8.2E-156 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPSF3K_RS10200 33a76932878861f6c7653a28895791d6 488 ProSitePatterns PS00571 Amidases signature. 150 181 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 SPSF3K_RS10200 33a76932878861f6c7653a28895791d6 488 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 475 88.672 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPSF3K_RS10200 33a76932878861f6c7653a28895791d6 488 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 475 1.6E-183 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPSF3K_RS08265 c7abaea97c848e263947d1e1c8db65c5 48 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 8 48 4.2E-14 T 29-03-2018 IPR021008 Protein of unknown function DUF3687 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 Pfam PF01336 OB-fold nucleic acid binding domain 20 106 2.2E-14 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 SUPERFAMILY SSF50249 12 113 1.5E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 448 39.821 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 442 1.6E-79 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 Gene3D G3DSA:3.30.930.10 113 448 3.4E-84 T 29-03-2018 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 SUPERFAMILY SSF55681 121 442 2.49E-88 T 29-03-2018 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 403 417 9.0E-15 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 363 379 9.0E-15 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 9.0E-15 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 9.0E-15 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 8 447 2.1E-142 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 SPSF3K_RS04545 2102b34a0abc364f1984462ca338eeeb 448 Gene3D G3DSA:2.40.50.140 4 112 1.6E-17 T 29-03-2018 SPSF3K_RS07255 79188d5e38abf67679de4c323431e629 185 Gene3D G3DSA:2.10.109.10 22 184 5.0E-24 T 29-03-2018 SPSF3K_RS07255 79188d5e38abf67679de4c323431e629 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 1.5E-9 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPSF3K_RS07255 79188d5e38abf67679de4c323431e629 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 26 42 1.5E-9 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPSF3K_RS07255 79188d5e38abf67679de4c323431e629 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 71 83 1.5E-9 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPSF3K_RS07255 79188d5e38abf67679de4c323431e629 185 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 10 177 1.2E-34 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPSF3K_RS07255 79188d5e38abf67679de4c323431e629 185 Pfam PF00717 Peptidase S24-like 33 94 5.5E-6 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SPSF3K_RS07255 79188d5e38abf67679de4c323431e629 185 SUPERFAMILY SSF51306 25 182 4.08E-35 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SPSF3K_RS08480 70111e353ef5768197478e11ce9f68cf 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 4.6E-154 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08480 70111e353ef5768197478e11ce9f68cf 419 SUPERFAMILY SSF55205 1 418 3.11E-131 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SPSF3K_RS08480 70111e353ef5768197478e11ce9f68cf 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 2.6E-88 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SPSF3K_RS08480 70111e353ef5768197478e11ce9f68cf 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 40.394 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08480 70111e353ef5768197478e11ce9f68cf 419 Gene3D G3DSA:3.65.10.10 21 221 9.5E-44 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SPSF3K_RS08480 70111e353ef5768197478e11ce9f68cf 419 Gene3D G3DSA:3.65.10.10 222 419 2.3E-46 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 307.932 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 Pfam PF03144 Elongation factor Tu domain 2 214 284 1.1E-7 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 SUPERFAMILY SSF54980 408 503 3.31E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 Gene3D G3DSA:3.30.70.240 401 559 4.7E-30 T 29-03-2018 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 Gene3D G3DSA:3.30.70.870 297 376 1.0E-28 T 29-03-2018 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 SMART SM00838 407 495 7.1E-5 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 Pfam PF00679 Elongation factor G C-terminus 408 495 5.0E-25 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 Gene3D G3DSA:3.40.50.300 8 194 5.6E-36 T 29-03-2018 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 Gene3D G3DSA:2.40.30.10 197 296 9.7E-25 T 29-03-2018 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 SUPERFAMILY SSF52540 5 234 3.65E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 5.1E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 SUPERFAMILY SSF54980 301 379 1.12E-19 T 29-03-2018 IPR035647 EF-G domain III/V-like SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 183 4.3E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 2.9E-50 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 PRINTS PR00315 GTP-binding elongation factor signature 15 28 4.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS07925 001600f15c0b8c5ae56d8494f5ae9126 610 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS01880 10ebf73ddaa0f9f137add31d0d47e7e5 581 SMART SM00382 369 554 1.7E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS01880 10ebf73ddaa0f9f137add31d0d47e7e5 581 Gene3D G3DSA:3.40.50.300 327 579 6.3E-58 T 29-03-2018 SPSF3K_RS01880 10ebf73ddaa0f9f137add31d0d47e7e5 581 Pfam PF00005 ABC transporter 360 507 4.8E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS01880 10ebf73ddaa0f9f137add31d0d47e7e5 581 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 14 538 2.5E-140 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 SPSF3K_RS01880 10ebf73ddaa0f9f137add31d0d47e7e5 581 SUPERFAMILY SSF52540 337 575 4.1E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01880 10ebf73ddaa0f9f137add31d0d47e7e5 581 Gene3D G3DSA:1.20.1560.10 14 326 1.9E-20 T 29-03-2018 SPSF3K_RS01880 10ebf73ddaa0f9f137add31d0d47e7e5 581 SUPERFAMILY SSF90123 15 324 7.32E-32 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS05210 2d8a5465948ef86ebb4c5b53f377a55b 173 Pfam PF00156 Phosphoribosyl transferase domain 3 155 1.2E-21 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPSF3K_RS05210 2d8a5465948ef86ebb4c5b53f377a55b 173 SUPERFAMILY SSF53271 4 167 3.54E-35 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS05210 2d8a5465948ef86ebb4c5b53f377a55b 173 Gene3D G3DSA:3.40.50.2020 1 173 4.5E-32 T 29-03-2018 SPSF3K_RS05210 2d8a5465948ef86ebb4c5b53f377a55b 173 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 171 35.714 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SPSF3K_RS07985 e46da29725562eafdfad13de369bb9ae 263 SUPERFAMILY SSF52317 34 207 4.01E-30 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS07985 e46da29725562eafdfad13de369bb9ae 263 Gene3D G3DSA:3.40.50.880 16 232 1.9E-22 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS07985 e46da29725562eafdfad13de369bb9ae 263 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 19 214 1.6E-46 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 449 2.4E-35 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 2 450 5.5E-212 T 29-03-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 SUPERFAMILY SSF55424 336 450 1.01E-36 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PIRSF PIRSF000350 1 446 3.4E-79 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 Gene3D G3DSA:3.50.50.60 1 166 1.7E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 Gene3D G3DSA:3.30.390.30 332 450 1.8E-37 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 Gene3D G3DSA:3.40.50.720 167 325 5.4E-32 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.0E-24 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.0E-24 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.0E-24 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 1.0E-24 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 1.0E-24 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 318 4.2E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 5.1E-65 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 5.1E-65 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 5.1E-65 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 5.1E-65 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 5.1E-65 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 5.1E-65 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 5.1E-65 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 5.1E-65 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 5.1E-65 T 29-03-2018 SPSF3K_RS05150 1c4f5824d74c3901cced80412da9886a 450 SUPERFAMILY SSF51905 1 363 2.45E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.0E-22 T 29-03-2018 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 2.0E-22 T 29-03-2018 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 2.0E-22 T 29-03-2018 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.0E-22 T 29-03-2018 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.0E-22 T 29-03-2018 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 SUPERFAMILY SSF55424 333 453 2.41E-30 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 107 116 7.6E-8 T 29-03-2018 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 7.6E-8 T 29-03-2018 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 7.6E-8 T 29-03-2018 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 261 7.6E-8 T 29-03-2018 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 SUPERFAMILY SSF51905 2 327 2.59E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 Gene3D G3DSA:3.50.50.60 257 339 1.7E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 Gene3D G3DSA:3.50.50.60 1 105 9.0E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 Gene3D G3DSA:3.50.50.60 106 255 6.0E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 441 1.4E-12 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 317 8.0E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06400 23d3972c9e12e8578dca8b67edb14550 455 Gene3D G3DSA:3.30.390.30 340 455 4.1E-20 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS08675 2b838537a699eccddb5bdc04ae919ea3 225 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 161 222 4.4E-19 T 29-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain SPSF3K_RS08675 2b838537a699eccddb5bdc04ae919ea3 225 Pfam PF12836 Helix-hairpin-helix motif 162 222 2.2E-22 T 29-03-2018 SPSF3K_RS08675 2b838537a699eccddb5bdc04ae919ea3 225 Gene3D G3DSA:3.10.560.10 63 162 4.0E-14 T 29-03-2018 SPSF3K_RS08675 2b838537a699eccddb5bdc04ae919ea3 225 SUPERFAMILY SSF47781 156 221 6.0E-26 T 29-03-2018 IPR010994 RuvA domain 2-like SPSF3K_RS08675 2b838537a699eccddb5bdc04ae919ea3 225 Pfam PF10531 SLBB domain 83 136 6.5E-12 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 SPSF3K_RS08675 2b838537a699eccddb5bdc04ae919ea3 225 SMART SM00278 172 191 0.027 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPSF3K_RS08675 2b838537a699eccddb5bdc04ae919ea3 225 SMART SM00278 202 221 0.17 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPSF3K_RS08675 2b838537a699eccddb5bdc04ae919ea3 225 Gene3D G3DSA:1.10.150.280 163 225 2.8E-22 T 29-03-2018 SPSF3K_RS06120 b143dbbbd70f72131363a5bfd8930be1 384 SUPERFAMILY SSF52540 5 248 8.73E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06120 b143dbbbd70f72131363a5bfd8930be1 384 SMART SM00382 32 215 2.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS06120 b143dbbbd70f72131363a5bfd8930be1 384 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS06120 b143dbbbd70f72131363a5bfd8930be1 384 Gene3D G3DSA:3.40.50.300 1 243 3.2E-79 T 29-03-2018 SPSF3K_RS06120 b143dbbbd70f72131363a5bfd8930be1 384 Pfam PF00005 ABC transporter 23 165 9.3E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS06120 b143dbbbd70f72131363a5bfd8930be1 384 Gene3D G3DSA:2.40.50.100 244 294 0.059 T 29-03-2018 SPSF3K_RS06120 b143dbbbd70f72131363a5bfd8930be1 384 SUPERFAMILY SSF50331 240 345 1.81E-11 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SPSF3K_RS06120 b143dbbbd70f72131363a5bfd8930be1 384 Pfam PF08402 TOBE domain 277 345 5.6E-5 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SPSF3K_RS00850 e2720dee4ebfb9049c2b06c21772176d 239 Pfam PF00717 Peptidase S24-like 151 216 3.4E-11 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SPSF3K_RS00850 e2720dee4ebfb9049c2b06c21772176d 239 Gene3D G3DSA:1.10.3100.10 1 128 8.3E-19 T 29-03-2018 IPR027910 YdiL-like domain SPSF3K_RS00850 e2720dee4ebfb9049c2b06c21772176d 239 SMART SM00530 7 62 7.3E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS00850 e2720dee4ebfb9049c2b06c21772176d 239 SUPERFAMILY SSF47413 2 69 1.18E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS00850 e2720dee4ebfb9049c2b06c21772176d 239 Gene3D G3DSA:2.10.109.10 129 233 5.5E-16 T 29-03-2018 SPSF3K_RS00850 e2720dee4ebfb9049c2b06c21772176d 239 SUPERFAMILY SSF51306 112 218 9.68E-19 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SPSF3K_RS00850 e2720dee4ebfb9049c2b06c21772176d 239 Pfam PF01381 Helix-turn-helix 8 58 1.9E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS07685 54b0ebdecc27c43b422eb19b9da0ff58 209 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 141 1.6E-6 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS07685 54b0ebdecc27c43b422eb19b9da0ff58 209 SUPERFAMILY SSF51161 31 191 9.43E-37 T 29-03-2018 IPR011004 Trimeric LpxA-like SPSF3K_RS07685 54b0ebdecc27c43b422eb19b9da0ff58 209 Gene3D G3DSA:2.160.10.10 4 207 7.1E-35 T 29-03-2018 SPSF3K_RS08435 6953801136c11a019e3cbf4ba2c4f705 452 SUPERFAMILY SSF53335 74 450 7.02E-72 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS08435 6953801136c11a019e3cbf4ba2c4f705 452 SUPERFAMILY SSF50249 2 57 2.8E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS08435 6953801136c11a019e3cbf4ba2c4f705 452 Gene3D G3DSA:2.40.50.140 1 57 1.2E-18 T 29-03-2018 SPSF3K_RS08435 6953801136c11a019e3cbf4ba2c4f705 452 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 433 443 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site SPSF3K_RS08435 6953801136c11a019e3cbf4ba2c4f705 452 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 381 412 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site SPSF3K_RS08435 6953801136c11a019e3cbf4ba2c4f705 452 Gene3D G3DSA:3.40.50.150 235 449 4.8E-44 T 29-03-2018 SPSF3K_RS08435 6953801136c11a019e3cbf4ba2c4f705 452 Gene3D G3DSA:3.40.50.150 72 154 0.0044 T 29-03-2018 SPSF3K_RS08435 6953801136c11a019e3cbf4ba2c4f705 452 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 273 451 3.1E-24 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 SPSF3K_RS08435 6953801136c11a019e3cbf4ba2c4f705 452 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 15 443 2.4E-131 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 SPSF3K_RS09100 cb699a75af7e36e6f5388d10d3e83923 360 SUPERFAMILY SSF142906 103 227 9.42E-25 T 29-03-2018 SPSF3K_RS09100 cb699a75af7e36e6f5388d10d3e83923 360 SUPERFAMILY SSF88697 236 300 5.8E-5 T 29-03-2018 IPR015947 PUA-like domain SPSF3K_RS09100 cb699a75af7e36e6f5388d10d3e83923 360 Pfam PF04237 YjbR 123 222 6.5E-15 T 29-03-2018 IPR007351 Uncharacterised protein YjbR SPSF3K_RS07240 86686ac06768f02056e69f5f8dbddd57 650 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 514 639 9.9E-8 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS07240 86686ac06768f02056e69f5f8dbddd57 650 Gene3D G3DSA:1.10.10.10 1 65 1.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07240 86686ac06768f02056e69f5f8dbddd57 650 Gene3D G3DSA:1.10.10.10 78 145 1.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07240 86686ac06768f02056e69f5f8dbddd57 650 Gene3D G3DSA:3.40.930.10 479 647 3.1E-11 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS07240 86686ac06768f02056e69f5f8dbddd57 650 SUPERFAMILY SSF46785 1 54 4.49E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07240 86686ac06768f02056e69f5f8dbddd57 650 SUPERFAMILY SSF55804 509 640 4.36E-11 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS07240 86686ac06768f02056e69f5f8dbddd57 650 Pfam PF08279 HTH domain 84 139 1.1E-7 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SPSF3K_RS07240 86686ac06768f02056e69f5f8dbddd57 650 Pfam PF08279 HTH domain 6 62 2.6E-6 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SPSF3K_RS08395 5771f6d1fe435d4e8352e790aee3f1cc 220 Pfam PF00072 Response regulator receiver domain 4 113 3.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS08395 5771f6d1fe435d4e8352e790aee3f1cc 220 Gene3D G3DSA:3.40.50.2300 1 122 7.8E-33 T 29-03-2018 SPSF3K_RS08395 5771f6d1fe435d4e8352e790aee3f1cc 220 SMART SM00862 143 219 1.7E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS08395 5771f6d1fe435d4e8352e790aee3f1cc 220 SMART SM00448 2 112 2.3E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS08395 5771f6d1fe435d4e8352e790aee3f1cc 220 Gene3D G3DSA:1.10.10.10 123 220 8.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08395 5771f6d1fe435d4e8352e790aee3f1cc 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 3.3E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS08395 5771f6d1fe435d4e8352e790aee3f1cc 220 SUPERFAMILY SSF52172 1 170 6.34E-36 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS07880 e5bf26124c226282c7625786addbffa6 194 Gene3D G3DSA:3.40.50.720 1 192 8.7E-16 T 29-03-2018 SPSF3K_RS07880 e5bf26124c226282c7625786addbffa6 194 SUPERFAMILY SSF51735 1 186 2.73E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS07880 e5bf26124c226282c7625786addbffa6 194 Pfam PF13460 NAD(P)H-binding 8 182 2.5E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 Gene3D G3DSA:1.10.10.10 85 150 8.5E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 Gene3D G3DSA:1.10.10.10 3 65 0.0013 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 Gene3D G3DSA:3.40.50.2300 397 485 7.1E-12 T 29-03-2018 SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 Pfam PF00874 PRD domain 299 387 1.3E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 SUPERFAMILY SSF55804 533 678 1.83E-36 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 SUPERFAMILY SSF52794 399 471 7.85E-5 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 Gene3D G3DSA:3.40.930.10 533 680 7.7E-31 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 537 678 2.5E-31 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 583 599 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 Gene3D G3DSA:1.10.1790.10 281 392 3.9E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00560 6cac673fe83b766558a26b373d83e2cd 680 SUPERFAMILY SSF63520 273 392 5.49E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 479 1.1E-159 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 SMART SM00116 100 150 4.0E-9 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 SMART SM00116 163 211 1.6E-9 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 300 312 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 PIRSF PIRSF000130 3 493 7.0E-209 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 SUPERFAMILY SSF51412 7 94 2.75E-122 T 29-03-2018 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 SUPERFAMILY SSF51412 222 483 2.75E-122 T 29-03-2018 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 Gene3D G3DSA:3.20.20.70 4 488 2.5E-111 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 SMART SM01240 11 479 0.0 T 29-03-2018 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 SUPERFAMILY SSF54631 99 210 5.56E-30 T 29-03-2018 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 Pfam PF00571 CBS domain 100 146 8.6E-8 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 Pfam PF00571 CBS domain 160 206 7.6E-8 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 492 83.913 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SPSF3K_RS00055 80d9b12b926bc368335f68d1f18d4d30 493 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 460 1.9E-194 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 SPSF3K_RS01440 1528f3406908b2a58104c4b9884d051d 373 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 15 366 2.5E-132 T 29-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPSF3K_RS01440 1528f3406908b2a58104c4b9884d051d 373 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 15 372 1.7E-153 T 29-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPSF3K_RS01440 1528f3406908b2a58104c4b9884d051d 373 PIRSF PIRSF015658 2 373 7.8E-160 T 29-03-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPSF3K_RS08650 a964aa53d1da7df49567001d34216343 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 3.6E-136 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 SPSF3K_RS08650 a964aa53d1da7df49567001d34216343 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 2.0E-137 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 SPSF3K_RS08650 a964aa53d1da7df49567001d34216343 342 Gene3D G3DSA:3.40.1780.10 173 341 3.6E-64 T 29-03-2018 SPSF3K_RS08650 a964aa53d1da7df49567001d34216343 342 Gene3D G3DSA:3.40.1780.10 1 148 8.7E-40 T 29-03-2018 SPSF3K_RS08650 a964aa53d1da7df49567001d34216343 342 SUPERFAMILY SSF111337 1 341 5.75E-136 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 SPSF3K_RS08650 a964aa53d1da7df49567001d34216343 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 45.778 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 SPSF3K_RS04695 852829e73ddf9b3b150d1ed525c71385 186 SUPERFAMILY SSF56784 1 180 1.41E-33 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04695 852829e73ddf9b3b150d1ed525c71385 186 Gene3D G3DSA:1.10.150.240 16 69 3.2E-18 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SPSF3K_RS04695 852829e73ddf9b3b150d1ed525c71385 186 Gene3D G3DSA:3.40.50.1000 70 183 2.4E-16 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04695 852829e73ddf9b3b150d1ed525c71385 186 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 6 169 8.8E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS04695 852829e73ddf9b3b150d1ed525c71385 186 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 175 3.0E-19 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 Hamap MF_01895 Ribonuclease R [rnr]. 18 707 54.568 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 SUPERFAMILY SSF50249 628 705 2.76E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 Gene3D G3DSA:2.40.50.140 628 773 2.7E-16 T 29-03-2018 SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 Pfam PF00575 S1 RNA binding domain 627 705 3.0E-12 T 29-03-2018 IPR003029 S1 domain GO:0003676 SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 Pfam PF00773 RNB domain 252 578 1.3E-113 T 29-03-2018 SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 ProSitePatterns PS01175 Ribonuclease II family signature. 548 572 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 SMART SM00955 252 581 6.3E-171 T 29-03-2018 SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 SUPERFAMILY SSF50249 66 135 2.81E-10 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 SUPERFAMILY SSF50249 213 626 1.59E-139 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 707 1.2E-242 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 SUPERFAMILY SSF50249 126 227 5.14E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 SMART SM00316 626 707 2.6E-13 T 29-03-2018 IPR022967 RNA-binding domain, S1 SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 66 705 7.4E-186 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 SPSF3K_RS03985 fa3fc18e56e8181ad320aa11c7a5dd1f 774 Pfam PF08206 Ribonuclease B OB domain 72 129 1.5E-15 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain SPSF3K_RS07305 3f3a635a7ddc49c90d46f707f215dd5a 66 Pfam PF05532 CsbD-like 4 55 3.7E-14 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS07305 3f3a635a7ddc49c90d46f707f215dd5a 66 SUPERFAMILY SSF69047 1 65 9.81E-13 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS07305 3f3a635a7ddc49c90d46f707f215dd5a 66 Gene3D G3DSA:1.10.1470.10 1 66 8.6E-17 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 Gene3D G3DSA:2.40.50.140 135 197 3.3E-12 T 29-03-2018 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 SUPERFAMILY SSF69705 1 124 2.75E-35 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 Pfam PF08529 NusA N-terminal domain 4 124 1.3E-30 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 356 6.2E-112 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 Pfam PF13184 NusA-like KH domain 229 310 8.2E-31 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 384 26.914 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 SUPERFAMILY SSF50249 131 198 1.33E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 SMART SM00322 315 378 0.035 T 29-03-2018 IPR004087 K Homology domain GO:0003676 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 SMART SM00322 229 306 0.95 T 29-03-2018 IPR004087 K Homology domain GO:0003676 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 Gene3D G3DSA:3.30.300.20 287 356 1.3E-15 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 SUPERFAMILY SSF54814 292 357 1.11E-15 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 Gene3D G3DSA:3.30.300.20 198 286 5.5E-29 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 Gene3D G3DSA:3.30.1480.10 1 129 2.5E-37 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SPSF3K_RS09955 d91eb4927f85b26bbb2261359cf43a27 384 SUPERFAMILY SSF54814 199 271 9.81E-22 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 SUPERFAMILY SSF56601 265 617 4.7E-72 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 Pfam PF03793 PASTA domain 692 747 8.6E-9 T 29-03-2018 IPR005543 PASTA domain SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 SUPERFAMILY SSF54184 692 747 9.32E-12 T 29-03-2018 SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 SUPERFAMILY SSF56519 70 264 1.16E-47 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 Pfam PF03717 Penicillin-binding Protein dimerisation domain 73 246 9.7E-27 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 Gene3D G3DSA:3.40.710.10 261 619 1.1E-61 T 29-03-2018 SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 Pfam PF00905 Penicillin binding protein transpeptidase domain 291 596 2.5E-71 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 SUPERFAMILY SSF54184 631 689 5.36E-15 T 29-03-2018 SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 SMART SM00740 629 689 0.95 T 29-03-2018 IPR005543 PASTA domain SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 SMART SM00740 690 748 4.1E-10 T 29-03-2018 IPR005543 PASTA domain SPSF3K_RS09785 34055767373b910784d8b8f032f9a08d 748 Gene3D G3DSA:3.90.1310.10 37 260 3.4E-31 T 29-03-2018 SPSF3K_RS08755 7875f6526e481a9b6264018f4e70af02 173 PIRSF PIRSF037847 1 172 6.8E-62 T 29-03-2018 IPR026043 Transcription repressor NadR SPSF3K_RS08755 7875f6526e481a9b6264018f4e70af02 173 Pfam PF02829 3H domain 73 169 1.9E-31 T 29-03-2018 IPR004173 3H domain GO:0036094 SPSF3K_RS08755 7875f6526e481a9b6264018f4e70af02 173 Pfam PF08279 HTH domain 6 59 5.6E-14 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SPSF3K_RS08755 7875f6526e481a9b6264018f4e70af02 173 Gene3D G3DSA:3.30.1340.20 70 170 5.9E-34 T 29-03-2018 IPR004173 3H domain GO:0036094 SPSF3K_RS08755 7875f6526e481a9b6264018f4e70af02 173 Gene3D G3DSA:1.10.10.10 1 62 9.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08755 7875f6526e481a9b6264018f4e70af02 173 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 76 169 1.0E-26 T 29-03-2018 IPR004173 3H domain GO:0036094 SPSF3K_RS08755 7875f6526e481a9b6264018f4e70af02 173 SUPERFAMILY SSF46785 1 60 2.95E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08755 7875f6526e481a9b6264018f4e70af02 173 SUPERFAMILY SSF75500 68 170 5.49E-31 T 29-03-2018 IPR004173 3H domain GO:0036094 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.4E-47 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.5E-36 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.5E-36 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.5E-36 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.5E-36 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 SUPERFAMILY SSF54686 1 135 1.57E-53 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.69 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.6E-56 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10485 35455b4eb6270ece8ee31c4adb234ec2 137 Gene3D G3DSA:3.90.1170.10 3 137 1.2E-48 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS04005 02143c17894b5c11ed04a86decc74f3a 220 Gene3D G3DSA:3.40.109.10 1 220 4.8E-44 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SPSF3K_RS04005 02143c17894b5c11ed04a86decc74f3a 220 SUPERFAMILY SSF55469 8 217 1.57E-50 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SPSF3K_RS04005 02143c17894b5c11ed04a86decc74f3a 220 Pfam PF00881 Nitroreductase family 14 198 5.5E-29 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SPSF3K_RS00635 cd158add6fb4773419f5ee04c080f107 296 SUPERFAMILY SSF54593 1 265 7.97E-39 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS00635 cd158add6fb4773419f5ee04c080f107 296 Gene3D G3DSA:3.10.180.10 1 131 6.2E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS00635 cd158add6fb4773419f5ee04c080f107 296 Gene3D G3DSA:3.10.180.10 133 296 1.1E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS00635 cd158add6fb4773419f5ee04c080f107 296 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 254 4.1E-25 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPSF3K_RS09065 5149eb8901ea02f45c1eb6e831f6e8dc 498 Pfam PF03606 C4-dicarboxylate anaerobic carrier 11 495 9.7E-162 T 29-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 SPSF3K_RS02505 53243cf175ccc813743b3fd28f762836 282 Pfam PF13556 PucR C-terminal helix-turn-helix domain 231 277 6.4E-9 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain SPSF3K_RS02505 53243cf175ccc813743b3fd28f762836 282 SUPERFAMILY SSF46689 224 260 2.96E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS02505 53243cf175ccc813743b3fd28f762836 282 Gene3D G3DSA:1.10.10.60 202 262 2.6E-6 T 29-03-2018 SPSF3K_RS05345 733dbd14f0c843de826c1b82e98a230e 126 PIRSF PIRSF031568 1 126 3.2E-60 T 29-03-2018 IPR009530 Protein of unknown function DUF1149 SPSF3K_RS05345 733dbd14f0c843de826c1b82e98a230e 126 Gene3D G3DSA:3.10.420.10 1 124 2.2E-47 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SPSF3K_RS05345 733dbd14f0c843de826c1b82e98a230e 126 Pfam PF06619 Protein of unknown function (DUF1149) 1 124 3.8E-47 T 29-03-2018 IPR009530 Protein of unknown function DUF1149 SPSF3K_RS05345 733dbd14f0c843de826c1b82e98a230e 126 SUPERFAMILY SSF54611 1 124 6.87E-49 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SPSF3K_RS07435 66b8e23694ec2eb1062fa42afaf76547 100 SMART SM00530 4 59 7.6E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS07435 66b8e23694ec2eb1062fa42afaf76547 100 Gene3D G3DSA:1.10.10.10 56 99 0.23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07435 66b8e23694ec2eb1062fa42afaf76547 100 Pfam PF01381 Helix-turn-helix 5 59 1.5E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS07435 66b8e23694ec2eb1062fa42afaf76547 100 Gene3D G3DSA:1.10.260.40 1 55 1.7E-16 T 29-03-2018 SPSF3K_RS07435 66b8e23694ec2eb1062fa42afaf76547 100 SUPERFAMILY SSF47413 3 65 5.09E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS03845 692a3ea5be04c269fd293507d804735c 242 Gene3D G3DSA:3.40.1160.10 2 237 3.8E-41 T 29-03-2018 SPSF3K_RS03845 692a3ea5be04c269fd293507d804735c 242 SUPERFAMILY SSF53633 3 238 1.44E-71 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SPSF3K_RS03845 692a3ea5be04c269fd293507d804735c 242 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 5 236 2.1E-95 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SPSF3K_RS03845 692a3ea5be04c269fd293507d804735c 242 Pfam PF00696 Amino acid kinase family 6 216 3.0E-26 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SPSF3K_RS03845 692a3ea5be04c269fd293507d804735c 242 PIRSF PIRSF005650 1 242 7.1E-91 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 SPSF3K_RS03845 692a3ea5be04c269fd293507d804735c 242 Hamap MF_01220_B Uridylate kinase [pyrH]. 3 237 43.244 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 SPSF3K_RS02155 9fd064c73e02ebcc8989a5038767974a 253 Gene3D G3DSA:3.40.50.1000 1 40 0.026 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02155 9fd064c73e02ebcc8989a5038767974a 253 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 203 3.0E-22 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02155 9fd064c73e02ebcc8989a5038767974a 253 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 110 203 6.3E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS02155 9fd064c73e02ebcc8989a5038767974a 253 Gene3D G3DSA:3.40.50.1000 96 247 2.1E-25 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02155 9fd064c73e02ebcc8989a5038767974a 253 SUPERFAMILY SSF56784 1 243 3.34E-40 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09285 4656dca792c1f53d80e98d543c7f5c94 319 SUPERFAMILY SSF52833 42 156 1.6E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS09285 4656dca792c1f53d80e98d543c7f5c94 319 SUPERFAMILY SSF47616 176 317 3.34E-34 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SPSF3K_RS09285 4656dca792c1f53d80e98d543c7f5c94 319 Gene3D G3DSA:3.40.30.10 37 187 3.6E-37 T 29-03-2018 SPSF3K_RS09285 4656dca792c1f53d80e98d543c7f5c94 319 Gene3D G3DSA:1.20.1050.10 188 318 2.3E-42 T 29-03-2018 SPSF3K_RS09285 4656dca792c1f53d80e98d543c7f5c94 319 PIRSF PIRSF015753 5 319 1.5E-133 T 29-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 SPSF3K_RS09285 4656dca792c1f53d80e98d543c7f5c94 319 Pfam PF13410 Glutathione S-transferase, C-terminal domain 202 272 5.3E-12 T 29-03-2018 SPSF3K_RS09285 4656dca792c1f53d80e98d543c7f5c94 319 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 156 2.6E-21 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SPSF3K_RS05660 d2fe0bc00801264791848d5cfc8b3f05 189 SUPERFAMILY SSF46689 4 79 7.18E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS05660 d2fe0bc00801264791848d5cfc8b3f05 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 54 4.8E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS05660 d2fe0bc00801264791848d5cfc8b3f05 189 Gene3D G3DSA:1.10.10.60 41 155 1.6E-7 T 29-03-2018 SPSF3K_RS05660 d2fe0bc00801264791848d5cfc8b3f05 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS05660 d2fe0bc00801264791848d5cfc8b3f05 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.5E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS05660 d2fe0bc00801264791848d5cfc8b3f05 189 Gene3D G3DSA:1.10.10.60 3 40 1.1E-13 T 29-03-2018 SPSF3K_RS05410 c9ca1c537b5fb97cd8df5e5c546d9add 311 Gene3D G3DSA:3.30.230.10 1 163 2.4E-46 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS05410 c9ca1c537b5fb97cd8df5e5c546d9add 311 SUPERFAMILY SSF55060 169 302 9.64E-43 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS05410 c9ca1c537b5fb97cd8df5e5c546d9add 311 PIRSF PIRSF015950 1 311 2.7E-99 T 29-03-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 SPSF3K_RS05410 c9ca1c537b5fb97cd8df5e5c546d9add 311 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 7 301 1.7E-128 T 29-03-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 SPSF3K_RS05410 c9ca1c537b5fb97cd8df5e5c546d9add 311 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 98 109 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SPSF3K_RS05410 c9ca1c537b5fb97cd8df5e5c546d9add 311 Pfam PF00288 GHMP kinases N terminal domain 92 142 7.5E-8 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SPSF3K_RS05410 c9ca1c537b5fb97cd8df5e5c546d9add 311 SUPERFAMILY SSF54211 4 174 3.79E-32 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS05410 c9ca1c537b5fb97cd8df5e5c546d9add 311 Gene3D G3DSA:3.30.70.890 175 305 1.5E-40 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS04210 1d13292abf5902a2ec233e427116e5cc 239 SMART SM00862 154 230 3.1E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS04210 1d13292abf5902a2ec233e427116e5cc 239 Pfam PF00072 Response regulator receiver domain 5 115 9.2E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS04210 1d13292abf5902a2ec233e427116e5cc 239 Gene3D G3DSA:3.40.50.2300 1 127 3.7E-39 T 29-03-2018 SPSF3K_RS04210 1d13292abf5902a2ec233e427116e5cc 239 SUPERFAMILY SSF52172 2 123 9.25E-43 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS04210 1d13292abf5902a2ec233e427116e5cc 239 SUPERFAMILY SSF46894 130 230 4.54E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPSF3K_RS04210 1d13292abf5902a2ec233e427116e5cc 239 Gene3D G3DSA:1.10.10.10 128 237 2.0E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04210 1d13292abf5902a2ec233e427116e5cc 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 230 4.1E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS04210 1d13292abf5902a2ec233e427116e5cc 239 SMART SM00448 3 114 9.4E-46 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS08240 a4face589b7c88bdfba46614785c085f 427 SUPERFAMILY SSF51445 7 348 4.34E-83 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS08240 a4face589b7c88bdfba46614785c085f 427 Gene3D G3DSA:3.20.20.80 1 353 5.2E-79 T 29-03-2018 SPSF3K_RS08240 a4face589b7c88bdfba46614785c085f 427 SMART SM00642 16 347 3.2E-29 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS08240 a4face589b7c88bdfba46614785c085f 427 Pfam PF00128 Alpha amylase, catalytic domain 26 118 1.0E-24 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS08240 a4face589b7c88bdfba46614785c085f 427 Pfam PF00128 Alpha amylase, catalytic domain 135 314 2.3E-18 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS05810 368f9d5ac6fe757211095c9e1ebb4ffe 27 Pfam PF06308 23S rRNA methylase leader peptide (ErmC) 1 27 6.0E-16 T 29-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 SPSF3K_RS05810 368f9d5ac6fe757211095c9e1ebb4ffe 27 ProDom PD018707 LEADER PEPTIDE METHYLASE PLASMID RESISTANCE RRNA METHYLTRANSFERASE ERMB 23S ANTIBIOTIC 1 27 2.0E-8 T 29-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 SPSF3K_RS11070 72a4523044363d2d145ffac018513c83 297 Gene3D G3DSA:3.10.20.320 147 227 2.6E-22 T 29-03-2018 SPSF3K_RS11070 72a4523044363d2d145ffac018513c83 297 Gene3D G3DSA:3.10.20.320 72 146 3.6E-23 T 29-03-2018 SPSF3K_RS11070 72a4523044363d2d145ffac018513c83 297 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 263 296 1.6E-5 T 29-03-2018 SPSF3K_RS11070 72a4523044363d2d145ffac018513c83 297 Pfam PF06458 MucBP domain 149 212 1.4E-17 T 29-03-2018 IPR009459 MucBP domain SPSF3K_RS11070 72a4523044363d2d145ffac018513c83 297 Pfam PF06458 MucBP domain 80 141 1.8E-19 T 29-03-2018 IPR009459 MucBP domain SPSF3K_RS11070 72a4523044363d2d145ffac018513c83 297 Pfam PF00746 LPXTG cell wall anchor motif 258 296 2.5E-6 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor SPSF3K_RS02025 8527a9b411b00916755975d7455569e5 323 Pfam PF04392 ABC transporter substrate binding protein 34 313 1.7E-75 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein SPSF3K_RS02025 8527a9b411b00916755975d7455569e5 323 Gene3D G3DSA:3.40.50.2300 155 290 4.0E-16 T 29-03-2018 SPSF3K_RS02025 8527a9b411b00916755975d7455569e5 323 SUPERFAMILY SSF53822 48 263 5.84E-8 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS02025 8527a9b411b00916755975d7455569e5 323 Gene3D G3DSA:3.40.50.2300 31 154 2.8E-15 T 29-03-2018 SPSF3K_RS10655 8b5eb16b54ea7a490b97fc3fad303f8b 320 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 317 1.8E-121 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SPSF3K_RS10655 8b5eb16b54ea7a490b97fc3fad303f8b 320 SUPERFAMILY SSF53271 71 308 4.88E-62 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS10655 8b5eb16b54ea7a490b97fc3fad303f8b 320 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 4.8E-22 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SPSF3K_RS10655 8b5eb16b54ea7a490b97fc3fad303f8b 320 Gene3D G3DSA:3.40.50.2020 6 144 2.2E-62 T 29-03-2018 SPSF3K_RS10655 8b5eb16b54ea7a490b97fc3fad303f8b 320 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 122 1.5E-50 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SPSF3K_RS10655 8b5eb16b54ea7a490b97fc3fad303f8b 320 SMART SM01400 6 122 2.5E-78 T 29-03-2018 SPSF3K_RS10655 8b5eb16b54ea7a490b97fc3fad303f8b 320 Gene3D G3DSA:3.40.50.2020 145 318 6.8E-45 T 29-03-2018 SPSF3K_RS10655 8b5eb16b54ea7a490b97fc3fad303f8b 320 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 6 317 50.107 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SPSF3K_RS10655 8b5eb16b54ea7a490b97fc3fad303f8b 320 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 130 145 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 SPSF3K_RS05035 4e7c4b75c7c13e7c4843211b3b39fd89 310 Gene3D G3DSA:3.90.550.10 1 288 1.0E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS05035 4e7c4b75c7c13e7c4843211b3b39fd89 310 Pfam PF00535 Glycosyl transferase family 2 5 112 5.0E-18 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SPSF3K_RS05035 4e7c4b75c7c13e7c4843211b3b39fd89 310 SUPERFAMILY SSF53448 2 227 1.78E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Pfam PF05192 MutS domain III 255 546 1.1E-42 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 7 849 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Pfam PF00488 MutS domain V 598 785 1.5E-79 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 676 692 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 6 843 23.628 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Gene3D G3DSA:3.30.420.110 130 248 9.7E-21 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 SUPERFAMILY SSF55271 4 114 1.96E-40 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 PIRSF PIRSF037677 188 835 1.8E-128 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 PIRSF PIRSF037677 2 200 8.0E-35 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Gene3D G3DSA:3.40.1170.10 1 129 4.3E-45 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Pfam PF01624 MutS domain I 8 118 2.2E-42 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 SUPERFAMILY SSF48334 254 551 3.53E-87 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 SMART SM00533 270 578 2.6E-106 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Pfam PF05190 MutS family domain IV 415 506 1.0E-26 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 SMART SM00534 595 782 9.0E-109 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Gene3D G3DSA:3.40.50.300 554 826 1.3E-42 T 29-03-2018 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 SUPERFAMILY SSF53150 120 265 8.11E-31 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Gene3D G3DSA:1.10.1420.10 249 394 1.9E-36 T 29-03-2018 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Gene3D G3DSA:1.10.1420.10 395 522 6.8E-30 T 29-03-2018 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 Pfam PF05188 MutS domain II 126 238 8.1E-13 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 SPSF3K_RS00345 e8e475e1bcf35a38fed8dd3def84a87e 851 SUPERFAMILY SSF52540 554 786 1.57E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09365 61ffe635e1f0eb58fcb8654d7d73d8c7 193 Gene3D G3DSA:3.40.50.1110 1 193 7.3E-26 T 29-03-2018 SPSF3K_RS09365 61ffe635e1f0eb58fcb8654d7d73d8c7 193 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 181 1.0E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SPSF3K_RS09365 61ffe635e1f0eb58fcb8654d7d73d8c7 193 SUPERFAMILY SSF52266 2 190 2.29E-31 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SPSF3K_RS06765 897cf037d42367e3fefc18aa94985b40 134 SUPERFAMILY SSF52540 5 113 1.3E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06765 897cf037d42367e3fefc18aa94985b40 134 Gene3D G3DSA:3.30.450.90 1 108 3.5E-20 T 29-03-2018 SPSF3K_RS04990 0bfdb27dda16d14106adc39260075b3c 376 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 218 231 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SPSF3K_RS04990 0bfdb27dda16d14106adc39260075b3c 376 SUPERFAMILY SSF53383 49 369 8.72E-72 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS04990 0bfdb27dda16d14106adc39260075b3c 376 Pfam PF00155 Aminotransferase class I and II 53 356 2.4E-45 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SPSF3K_RS04990 0bfdb27dda16d14106adc39260075b3c 376 Gene3D G3DSA:3.90.1150.10 284 368 1.4E-6 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS04990 0bfdb27dda16d14106adc39260075b3c 376 Gene3D G3DSA:3.40.640.10 44 283 3.9E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS03155 2b22f7096d3bb28a3503d12737e721ba 246 SUPERFAMILY SSF53335 3 246 8.82E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS03155 2b22f7096d3bb28a3503d12737e721ba 246 Gene3D G3DSA:3.40.50.150 2 139 1.9E-24 T 29-03-2018 SPSF3K_RS03155 2b22f7096d3bb28a3503d12737e721ba 246 Pfam PF13649 Methyltransferase domain 41 135 1.1E-17 T 29-03-2018 SPSF3K_RS03155 2b22f7096d3bb28a3503d12737e721ba 246 Gene3D G3DSA:2.20.25.110 143 205 1.2E-19 T 29-03-2018 SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 Pfam PF00149 Calcineurin-like phosphoesterase 5 201 1.5E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 PIRSF PIRSF036361 1 442 2.0E-164 T 29-03-2018 IPR011240 Phosphoesterase-related protein YunD SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 SUPERFAMILY SSF56300 4 270 1.79E-58 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 Gene3D G3DSA:3.90.780.10 288 442 4.8E-13 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 PRINTS PR01607 Apyrase family signature 3 21 7.9E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 PRINTS PR01607 Apyrase family signature 184 207 7.9E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 PRINTS PR01607 Apyrase family signature 212 232 7.9E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 PRINTS PR01607 Apyrase family signature 165 182 7.9E-14 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 Gene3D G3DSA:3.60.21.10 1 287 4.9E-52 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS09000 2ff47f959814dc83ec4f4fde4595ab13 442 SUPERFAMILY SSF55816 289 442 7.65E-11 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 SPSF3K_RS09735 70aa298c044c44ccdfe7fab34073d920 274 Gene3D G3DSA:3.40.50.620 2 274 2.4E-55 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS09735 70aa298c044c44ccdfe7fab34073d920 274 SUPERFAMILY SSF52402 3 273 4.57E-82 T 29-03-2018 SPSF3K_RS09735 70aa298c044c44ccdfe7fab34073d920 274 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 274 6.5E-70 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 SPSF3K_RS09735 70aa298c044c44ccdfe7fab34073d920 274 Pfam PF02540 NAD synthase 23 265 4.5E-65 T 29-03-2018 IPR022310 NAD/GMP synthase SPSF3K_RS09735 70aa298c044c44ccdfe7fab34073d920 274 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 268 29.344 T 29-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 SPSF3K_RS10405 363da2e02d1259a7a20bd6bc6d646820 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10405 363da2e02d1259a7a20bd6bc6d646820 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 5.4E-23 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10405 363da2e02d1259a7a20bd6bc6d646820 38 Pfam PF00444 Ribosomal protein L36 1 38 4.6E-22 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10405 363da2e02d1259a7a20bd6bc6d646820 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.445 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10405 363da2e02d1259a7a20bd6bc6d646820 38 SUPERFAMILY SSF57840 1 38 7.46E-18 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10405 363da2e02d1259a7a20bd6bc6d646820 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 38 3.0E-10 T 29-03-2018 SPSF3K_RS10960 43b616e7e341ebf747ad8dc992ca4e25 410 Pfam PF03432 Relaxase/Mobilisation nuclease domain 9 280 3.5E-73 T 29-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 SPSF3K_RS11040 43b616e7e341ebf747ad8dc992ca4e25 410 Pfam PF03432 Relaxase/Mobilisation nuclease domain 9 280 3.5E-73 T 29-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 SPSF3K_RS01495 e41562d735a3f95002a3a10a8f6840b3 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 288 7.4E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01495 e41562d735a3f95002a3a10a8f6840b3 295 SUPERFAMILY SSF161098 12 295 5.56E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01495 e41562d735a3f95002a3a10a8f6840b3 295 Gene3D G3DSA:1.10.3720.10 12 289 8.6E-41 T 29-03-2018 SPSF3K_RS10110 9b09142b44077610100d839fb4429a26 324 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 323 1.7E-103 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SPSF3K_RS10110 9b09142b44077610100d839fb4429a26 324 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 237 324 1.4E-31 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SPSF3K_RS10110 9b09142b44077610100d839fb4429a26 324 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 2.4E-30 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SPSF3K_RS10110 9b09142b44077610100d839fb4429a26 324 Gene3D G3DSA:3.40.47.10 161 324 3.1E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS10110 9b09142b44077610100d839fb4429a26 324 SUPERFAMILY SSF53901 1 323 6.45E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS10110 9b09142b44077610100d839fb4429a26 324 Gene3D G3DSA:3.40.47.10 3 160 5.7E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS10110 9b09142b44077610100d839fb4429a26 324 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 324 63.943 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 SUPERFAMILY SSF55424 325 446 4.12E-29 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 4.6E-22 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 4.6E-22 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 4.6E-22 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.6E-22 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 4.6E-22 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Pfam PF01206 Sulfurtransferase TusA 575 644 6.2E-18 T 29-03-2018 IPR001455 TusA-like domain SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 9.1E-15 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 9.1E-15 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 388 403 9.1E-15 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 9.1E-15 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 9.1E-15 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 333 433 1.7E-11 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 SUPERFAMILY SSF51905 3 200 1.47E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Gene3D G3DSA:3.40.1260.10 660 818 3.9E-52 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 SMART SM00450 452 548 6.7E-16 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Gene3D G3DSA:3.40.50.720 134 302 4.5E-29 T 29-03-2018 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 294 1.3E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Gene3D G3DSA:3.30.390.30 328 445 6.6E-26 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 SUPERFAMILY SSF75169 760 807 2.94E-19 T 29-03-2018 IPR027396 DsrEFH-like SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 SUPERFAMILY SSF75169 670 713 2.94E-19 T 29-03-2018 IPR027396 DsrEFH-like SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Gene3D G3DSA:3.30.110.40 555 645 3.0E-22 T 29-03-2018 IPR001455 TusA-like domain SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 SUPERFAMILY SSF52821 436 549 1.02E-26 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 SUPERFAMILY SSF51905 157 321 1.73E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Gene3D G3DSA:3.50.50.60 1 133 3.3E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Pfam PF00581 Rhodanese-like domain 461 544 3.6E-11 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 SUPERFAMILY SSF64307 573 644 1.57E-17 T 29-03-2018 IPR001455 TusA-like domain SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Gene3D G3DSA:3.40.250.10 446 552 2.6E-23 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 577 601 - T 29-03-2018 IPR001455 TusA-like domain SPSF3K_RS06065 4caa00620406ea79453b6ea61982bf44 818 Pfam PF13686 DsrE/DsrF/DrsH-like family 669 817 4.1E-53 T 29-03-2018 IPR032836 DsrE2-like family SPSF3K_RS02110 7869eb1f97a387903e5808cecfe44b5f 421 Pfam PF01042 Endoribonuclease L-PSP 32 126 7.3E-22 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SPSF3K_RS02110 7869eb1f97a387903e5808cecfe44b5f 421 Pfam PF01042 Endoribonuclease L-PSP 169 272 2.2E-21 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SPSF3K_RS02110 7869eb1f97a387903e5808cecfe44b5f 421 Pfam PF01042 Endoribonuclease L-PSP 299 411 4.8E-25 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SPSF3K_RS02110 7869eb1f97a387903e5808cecfe44b5f 421 SUPERFAMILY SSF55298 290 413 4.87E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS02110 7869eb1f97a387903e5808cecfe44b5f 421 SUPERFAMILY SSF55298 14 133 4.56E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS02110 7869eb1f97a387903e5808cecfe44b5f 421 Gene3D G3DSA:3.30.1330.40 142 282 1.0E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS02110 7869eb1f97a387903e5808cecfe44b5f 421 Gene3D G3DSA:3.30.1330.40 4 134 1.9E-24 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS02110 7869eb1f97a387903e5808cecfe44b5f 421 Gene3D G3DSA:3.30.1330.40 291 417 6.8E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS02110 7869eb1f97a387903e5808cecfe44b5f 421 SUPERFAMILY SSF55298 145 280 2.04E-30 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS07465 60b2a1b6ee73776ad58712b7f6326380 798 SUPERFAMILY SSF46785 725 795 1.14E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07465 60b2a1b6ee73776ad58712b7f6326380 798 Pfam PF03288 Poxvirus D5 protein-like 719 791 3.5E-14 T 29-03-2018 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal SPSF3K_RS07465 60b2a1b6ee73776ad58712b7f6326380 798 Gene3D G3DSA:1.10.10.10 724 796 2.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07465 60b2a1b6ee73776ad58712b7f6326380 798 Gene3D G3DSA:3.40.50.300 485 697 1.7E-12 T 29-03-2018 SPSF3K_RS07465 60b2a1b6ee73776ad58712b7f6326380 798 Pfam PF08706 D5 N terminal like 431 517 3.8E-8 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal SPSF3K_RS07465 60b2a1b6ee73776ad58712b7f6326380 798 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 467 765 2.4E-97 T 29-03-2018 IPR006500 DNA primase, phage/plasmid SPSF3K_RS07465 60b2a1b6ee73776ad58712b7f6326380 798 SUPERFAMILY SSF52540 515 693 5.84E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07465 60b2a1b6ee73776ad58712b7f6326380 798 SMART SM00885 387 518 4.2E-15 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal SPSF3K_RS02705 ecebae8839bd35ad6e9c7ca870ae1b3b 92 Gene3D G3DSA:1.10.10.10 45 92 1.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02705 ecebae8839bd35ad6e9c7ca870ae1b3b 92 SUPERFAMILY SSF46955 42 90 1.32E-7 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 3.6E-23 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 Gene3D G3DSA:3.90.1170.30 332 416 5.1E-21 T 29-03-2018 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 Gene3D G3DSA:1.20.970.10 1 66 5.7E-26 T 29-03-2018 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 Pfam PF00591 Glycosyl transferase family, a/b domain 79 301 3.2E-36 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 SUPERFAMILY SSF54680 326 421 6.93E-23 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 410 5.9E-171 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 SUPERFAMILY SSF52418 69 320 1.57E-84 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 338 411 3.9E-21 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 SUPERFAMILY SSF47648 1 69 1.18E-23 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 Gene3D G3DSA:3.40.1030.10 68 331 2.8E-87 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 SMART SM00941 338 411 2.6E-23 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 PIRSF PIRSF000478 1 425 2.6E-158 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS07020 81b77feedc37c8670b4c26542a0abbc5 425 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 SPSF3K_RS02660 961e064a05c9931cd491646f7a52e01a 249 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 12 248 1.4E-78 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 SPSF3K_RS02660 961e064a05c9931cd491646f7a52e01a 249 SUPERFAMILY SSF75217 78 247 9.16E-47 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SPSF3K_RS02660 961e064a05c9931cd491646f7a52e01a 249 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 14 86 4.9E-15 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SPSF3K_RS02660 961e064a05c9931cd491646f7a52e01a 249 Gene3D G3DSA:3.40.1280.10 83 249 9.1E-45 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPSF3K_RS02660 961e064a05c9931cd491646f7a52e01a 249 Gene3D G3DSA:3.30.1330.30 4 82 1.1E-15 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SPSF3K_RS02660 961e064a05c9931cd491646f7a52e01a 249 SMART SM00967 13 87 4.1E-14 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 SPSF3K_RS02660 961e064a05c9931cd491646f7a52e01a 249 Pfam PF00588 SpoU rRNA Methylase family 103 242 5.4E-40 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SPSF3K_RS02660 961e064a05c9931cd491646f7a52e01a 249 SUPERFAMILY SSF55315 7 84 4.71E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like SPSF3K_RS02195 bfa5bf4d56fa85829425913899e7ff33 304 Pfam PF01022 Bacterial regulatory protein, arsR family 38 66 1.7E-4 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS02195 bfa5bf4d56fa85829425913899e7ff33 304 Gene3D G3DSA:1.10.10.10 2 91 7.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02195 bfa5bf4d56fa85829425913899e7ff33 304 SUPERFAMILY SSF46785 8 233 1.23E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05670 dfa0ac6478c957ef74527c98f1c8eb0e 250 SUPERFAMILY SSF52343 129 246 6.42E-10 T 29-03-2018 SPSF3K_RS05670 dfa0ac6478c957ef74527c98f1c8eb0e 250 Gene3D G3DSA:2.40.30.10 31 126 9.4E-8 T 29-03-2018 SPSF3K_RS05670 dfa0ac6478c957ef74527c98f1c8eb0e 250 SUPERFAMILY SSF63380 34 120 1.21E-5 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 SPSF3K_RS05670 dfa0ac6478c957ef74527c98f1c8eb0e 250 Gene3D G3DSA:3.40.50.80 127 250 2.5E-6 T 29-03-2018 SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 SMART SM00358 161 228 4.6E-22 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 227 9.6E-80 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 Gene3D G3DSA:1.10.1520.10 4 153 1.4E-41 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 ProSitePatterns PS00517 Ribonuclease III family signature. 44 52 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 SUPERFAMILY SSF69065 7 163 7.15E-50 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 Pfam PF14622 Ribonuclease-III-like 18 147 1.3E-35 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 224 30.553 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 SUPERFAMILY SSF54768 149 228 3.3E-23 T 29-03-2018 SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 Pfam PF00035 Double-stranded RNA binding motif 161 227 4.7E-17 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 Gene3D G3DSA:3.30.160.20 156 230 3.4E-22 T 29-03-2018 SPSF3K_RS04160 c3551b83c5fe99e58ba04356d125048c 230 SMART SM00535 20 155 2.7E-57 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SPSF3K_RS02665 6b57b1cdfebf82f48ea44a23dfb2226f 170 Gene3D G3DSA:3.40.50.1010 1 141 0.0013 T 29-03-2018 IPR029060 PIN domain-like SPSF3K_RS02665 6b57b1cdfebf82f48ea44a23dfb2226f 170 Pfam PF05991 YacP-like NYN domain 6 166 2.1E-49 T 29-03-2018 IPR010298 Protein of unknown function DUF901 SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Pfam PF08481 GBS Bsp-like repeat 431 510 5.0E-27 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 SMART SM00287 248 316 0.009 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 SMART SM00287 541 605 0.028 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 SMART SM00287 337 403 0.0049 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 SMART SM00287 152 216 1.4 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Pfam PF04650 YSIRK type signal peptide 8 32 3.2E-9 T 29-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Pfam PF08460 Bacterial SH3 domain 150 211 5.6E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Pfam PF08460 Bacterial SH3 domain 334 396 1.5E-20 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Pfam PF08460 Bacterial SH3 domain 245 307 6.9E-22 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Pfam PF08460 Bacterial SH3 domain 541 602 2.3E-16 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 39 3.6E-11 T 29-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Gene3D G3DSA:2.30.30.410 520 605 4.3E-12 T 29-03-2018 SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Gene3D G3DSA:2.30.30.410 318 412 5.4E-10 T 29-03-2018 SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Gene3D G3DSA:2.30.30.410 224 317 8.3E-10 T 29-03-2018 SPSF3K_RS06070 b47b62769cbaefe5c89f9586523bf118 605 Gene3D G3DSA:2.30.30.410 129 223 2.1E-5 T 29-03-2018 SPSF3K_RS03965 72d5b5d92a8dc2bb766e0ebc56c05955 500 Gene3D G3DSA:3.40.50.300 2 380 8.9E-28 T 29-03-2018 SPSF3K_RS03965 72d5b5d92a8dc2bb766e0ebc56c05955 500 Pfam PF05872 Bacterial protein of unknown function (DUF853) 6 499 3.8E-236 T 29-03-2018 IPR033186 Helicase HerA-like C-terminal SPSF3K_RS03965 72d5b5d92a8dc2bb766e0ebc56c05955 500 SUPERFAMILY SSF52540 11 380 2.59E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04100 494fbfb12df7153fb99ee97a9d424d5d 329 SUPERFAMILY SSF82549 11 329 5.23E-124 T 29-03-2018 SPSF3K_RS04100 494fbfb12df7153fb99ee97a9d424d5d 329 Gene3D G3DSA:3.30.1180.20 184 329 5.5E-43 T 29-03-2018 SPSF3K_RS04100 494fbfb12df7153fb99ee97a9d424d5d 329 Pfam PF02733 Dak1 domain 17 327 2.0E-118 T 29-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SPSF3K_RS04100 494fbfb12df7153fb99ee97a9d424d5d 329 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 2.0E-150 T 29-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 SPSF3K_RS04100 494fbfb12df7153fb99ee97a9d424d5d 329 Gene3D G3DSA:3.40.50.10440 11 183 6.4E-72 T 29-03-2018 SPSF3K_RS01095 efa2b3f524c3b8c4e01ca0d6f988f44f 308 Pfam PF00701 Dihydrodipicolinate synthetase family 7 285 2.6E-54 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS01095 efa2b3f524c3b8c4e01ca0d6f988f44f 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 7.0E-12 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS01095 efa2b3f524c3b8c4e01ca0d6f988f44f 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 7.0E-12 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS01095 efa2b3f524c3b8c4e01ca0d6f988f44f 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 7.0E-12 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS01095 efa2b3f524c3b8c4e01ca0d6f988f44f 308 PRINTS PR00146 Dihydrodipicolinate synthase signature 134 151 7.0E-12 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS01095 efa2b3f524c3b8c4e01ca0d6f988f44f 308 SUPERFAMILY SSF51569 6 292 6.18E-66 T 29-03-2018 SPSF3K_RS01095 efa2b3f524c3b8c4e01ca0d6f988f44f 308 Gene3D G3DSA:3.20.20.70 2 308 2.1E-60 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS01095 efa2b3f524c3b8c4e01ca0d6f988f44f 308 SMART SM01130 6 298 8.2E-61 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS01095 efa2b3f524c3b8c4e01ca0d6f988f44f 308 PIRSF PIRSF001365 2 307 3.8E-70 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS01945 1601cabb50893e1d895756f07dade70f 108 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 34 2.4E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site SPSF3K_RS01945 1601cabb50893e1d895756f07dade70f 108 PRINTS PR00813 Bacterial general secretion pathway protein G signature 15 40 1.7E-8 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SPSF3K_RS01945 1601cabb50893e1d895756f07dade70f 108 PRINTS PR00813 Bacterial general secretion pathway protein G signature 51 69 1.7E-8 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SPSF3K_RS01945 1601cabb50893e1d895756f07dade70f 108 SUPERFAMILY SSF54523 16 97 1.8E-12 T 29-03-2018 SPSF3K_RS01945 1601cabb50893e1d895756f07dade70f 108 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 34 1.3E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site SPSF3K_RS01945 1601cabb50893e1d895756f07dade70f 108 PIRSF PIRSF029928 1 108 1.6E-34 T 29-03-2018 IPR016940 ComG operon protein C GO:0030420 SPSF3K_RS01945 1601cabb50893e1d895756f07dade70f 108 Gene3D G3DSA:3.30.700.10 16 104 1.8E-10 T 29-03-2018 SPSF3K_RS00325 f9ba7c99187b19097ded78448dd18934 292 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 224 277 3.3E-18 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 SPSF3K_RS00325 f9ba7c99187b19097ded78448dd18934 292 PIRSF PIRSF006483 1 286 1.6E-79 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT SPSF3K_RS00325 f9ba7c99187b19097ded78448dd18934 292 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 218 9.7E-62 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT SPSF3K_RS05290 49e032bbc5e514a0730b3de14e410c8b 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 168 5.7E-49 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SPSF3K_RS05290 49e032bbc5e514a0730b3de14e410c8b 172 Gene3D G3DSA:2.40.30.60 2 91 2.4E-19 T 29-03-2018 IPR002676 RimM protein GO:0006364 SPSF3K_RS05290 49e032bbc5e514a0730b3de14e410c8b 172 Pfam PF05239 PRC-barrel domain 96 168 1.3E-12 T 29-03-2018 IPR027275 PRC-barrel domain SPSF3K_RS05290 49e032bbc5e514a0730b3de14e410c8b 172 SUPERFAMILY SSF50346 99 168 1.63E-18 T 29-03-2018 IPR011033 PRC-barrel-like SPSF3K_RS05290 49e032bbc5e514a0730b3de14e410c8b 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 3 168 23.584 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SPSF3K_RS05290 49e032bbc5e514a0730b3de14e410c8b 172 Pfam PF01782 RimM N-terminal domain 6 89 3.4E-19 T 29-03-2018 IPR002676 RimM protein GO:0006364 SPSF3K_RS05290 49e032bbc5e514a0730b3de14e410c8b 172 SUPERFAMILY SSF50447 2 91 1.2E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS05290 49e032bbc5e514a0730b3de14e410c8b 172 Gene3D G3DSA:2.30.30.240 95 163 5.7E-20 T 29-03-2018 SPSF3K_RS04205 36def4737ed533ffc52f0a622fb8ff75 127 Gene3D G3DSA:3.10.180.10 2 127 1.5E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS04205 36def4737ed533ffc52f0a622fb8ff75 127 SUPERFAMILY SSF54593 4 126 1.18E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS04205 36def4737ed533ffc52f0a622fb8ff75 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 125 1.0E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPSF3K_RS09775 69708fd19f7c4f5b5d95a94c26522d70 447 Pfam PF00271 Helicase conserved C-terminal domain 232 337 3.5E-24 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS09775 69708fd19f7c4f5b5d95a94c26522d70 447 Pfam PF00270 DEAD/DEAH box helicase 25 191 7.3E-42 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPSF3K_RS09775 69708fd19f7c4f5b5d95a94c26522d70 447 Gene3D G3DSA:3.40.50.300 228 447 3.2E-41 T 29-03-2018 SPSF3K_RS09775 69708fd19f7c4f5b5d95a94c26522d70 447 SMART SM00487 20 220 1.4E-51 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS09775 69708fd19f7c4f5b5d95a94c26522d70 447 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 1 435 50.013 T 29-03-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 SPSF3K_RS09775 69708fd19f7c4f5b5d95a94c26522d70 447 Gene3D G3DSA:3.40.50.300 1 227 2.6E-48 T 29-03-2018 SPSF3K_RS09775 69708fd19f7c4f5b5d95a94c26522d70 447 SMART SM00490 256 337 8.0E-27 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS09775 69708fd19f7c4f5b5d95a94c26522d70 447 SUPERFAMILY SSF52540 70 357 2.23E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04945 0f40a3bfd5ec85968188ebc6be81a364 174 Gene3D G3DSA:3.40.630.30 3 174 1.3E-26 T 29-03-2018 SPSF3K_RS04945 0f40a3bfd5ec85968188ebc6be81a364 174 Pfam PF00583 Acetyltransferase (GNAT) family 42 149 2.0E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS04945 0f40a3bfd5ec85968188ebc6be81a364 174 SUPERFAMILY SSF55729 4 166 5.06E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 SMART SM00345 7 66 1.9E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 4.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 4.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 Gene3D G3DSA:1.10.10.10 1 67 4.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 3 234 1.4E-91 T 29-03-2018 IPR012770 Trehalose operon transcriptional repressor SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 SUPERFAMILY SSF46785 2 79 6.23E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 3.4E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 Pfam PF07702 UTRA domain 91 227 1.4E-28 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 SMART SM00866 88 227 2.6E-18 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 Gene3D G3DSA:3.40.1410.10 72 236 1.1E-24 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS00545 dad9dd3fd1f06c85c1bb8fb0374ed22a 237 SUPERFAMILY SSF64288 54 235 6.6E-36 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS08615 5026d825812f8d704bc99f2504d6a9be 413 Gene3D G3DSA:1.20.1250.20 212 410 9.8E-23 T 29-03-2018 SPSF3K_RS08615 5026d825812f8d704bc99f2504d6a9be 413 SUPERFAMILY SSF103473 3 399 5.89E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS08615 5026d825812f8d704bc99f2504d6a9be 413 Pfam PF07690 Major Facilitator Superfamily 19 363 5.7E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS08615 5026d825812f8d704bc99f2504d6a9be 413 Gene3D G3DSA:1.20.1250.20 1 203 8.0E-27 T 29-03-2018 SPSF3K_RS03330 684224f4d07d2f5e401f78a571273ab7 264 SUPERFAMILY SSF53681 109 262 8.72E-41 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS03330 684224f4d07d2f5e401f78a571273ab7 264 SUPERFAMILY SSF53681 5 106 8.17E-35 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS03330 684224f4d07d2f5e401f78a571273ab7 264 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 253 1.9E-77 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS03330 684224f4d07d2f5e401f78a571273ab7 264 Hamap MF_00258 Glutamate racemase [murI]. 4 256 39.976 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS03330 684224f4d07d2f5e401f78a571273ab7 264 Gene3D G3DSA:3.40.50.1860 2 111 5.7E-26 T 29-03-2018 SPSF3K_RS03330 684224f4d07d2f5e401f78a571273ab7 264 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS03330 684224f4d07d2f5e401f78a571273ab7 264 Gene3D G3DSA:3.40.50.1860 112 264 3.3E-40 T 29-03-2018 SPSF3K_RS03330 684224f4d07d2f5e401f78a571273ab7 264 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 213 3.8E-36 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS09520 88de6109e3712995e01aa18d1e7a7a91 177 Hamap MF_01568 UPF0374 protein . 1 175 49.229 T 29-03-2018 IPR016882 Uncharacterised protein family UPF0374 SPSF3K_RS09520 88de6109e3712995e01aa18d1e7a7a91 177 SUPERFAMILY SSF159234 3 170 1.83E-33 T 29-03-2018 IPR007295 Domain of unknown function DUF402 SPSF3K_RS09520 88de6109e3712995e01aa18d1e7a7a91 177 Gene3D G3DSA:2.40.380.10 14 170 2.2E-32 T 29-03-2018 IPR007295 Domain of unknown function DUF402 SPSF3K_RS09520 88de6109e3712995e01aa18d1e7a7a91 177 PIRSF PIRSF028345 1 177 8.3E-77 T 29-03-2018 IPR016882 Uncharacterised protein family UPF0374 SPSF3K_RS09520 88de6109e3712995e01aa18d1e7a7a91 177 Pfam PF04167 Protein of unknown function (DUF402) 60 124 1.0E-16 T 29-03-2018 IPR007295 Domain of unknown function DUF402 SPSF3K_RS10660 5383c6ec16fcc54d7056563a8f00aeb7 451 SUPERFAMILY SSF54001 346 443 1.67E-20 T 29-03-2018 SPSF3K_RS10660 5383c6ec16fcc54d7056563a8f00aeb7 451 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 419 442 2.5E-42 T 29-03-2018 IPR009148 Streptococcal non-M secreted SibA SPSF3K_RS10660 5383c6ec16fcc54d7056563a8f00aeb7 451 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 377 401 2.5E-42 T 29-03-2018 IPR009148 Streptococcal non-M secreted SibA SPSF3K_RS10660 5383c6ec16fcc54d7056563a8f00aeb7 451 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 225 252 2.5E-42 T 29-03-2018 IPR009148 Streptococcal non-M secreted SibA SPSF3K_RS10660 5383c6ec16fcc54d7056563a8f00aeb7 451 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 352 374 2.5E-42 T 29-03-2018 IPR009148 Streptococcal non-M secreted SibA SPSF3K_RS10660 5383c6ec16fcc54d7056563a8f00aeb7 451 Gene3D G3DSA:1.20.5.1000 29 113 1.4E-5 T 29-03-2018 SPSF3K_RS10660 5383c6ec16fcc54d7056563a8f00aeb7 451 Pfam PF05257 CHAP domain 350 426 1.9E-11 T 29-03-2018 IPR007921 CHAP domain SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 PIRSF PIRSF000429 1 396 3.6E-137 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 Pfam PF02803 Thiolase, C-terminal domain 273 394 2.1E-50 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 SUPERFAMILY SSF53901 274 392 1.13E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 Gene3D G3DSA:3.40.47.10 268 392 1.4E-37 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 Gene3D G3DSA:3.40.47.10 1 185 7.8E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 Gene3D G3DSA:3.40.47.10 186 267 3.8E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 Pfam PF00108 Thiolase, N-terminal domain 5 265 2.5E-103 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 SUPERFAMILY SSF53901 4 272 4.8E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS04750 047e06c26ea8876fcae1a427d5d335ac 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 393 8.1E-152 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 SPSF3K_RS02685 677ec84411e39fe5f9c7a9fdd284a0b1 130 Gene3D G3DSA:3.30.230.10 3 130 3.1E-52 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS02685 677ec84411e39fe5f9c7a9fdd284a0b1 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.493 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid SPSF3K_RS02685 677ec84411e39fe5f9c7a9fdd284a0b1 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS02685 677ec84411e39fe5f9c7a9fdd284a0b1 130 SUPERFAMILY SSF54211 6 130 3.19E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS02685 677ec84411e39fe5f9c7a9fdd284a0b1 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 9.3E-47 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 SUPERFAMILY SSF81271 287 371 2.83E-35 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 5.3E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 5.3E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 5.3E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 5.3E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 SUPERFAMILY SSF52540 3 309 3.52E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 Pfam PF01926 50S ribosome-binding GTPase 5 113 4.8E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 Gene3D G3DSA:3.10.20.30 271 370 1.6E-45 T 29-03-2018 IPR012675 Beta-grasp domain SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 Gene3D G3DSA:1.10.150.300 123 205 1.7E-26 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 PIRSF PIRSF006641 1 371 1.5E-154 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 Pfam PF06071 Protein of unknown function (DUF933) 287 370 7.1E-40 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 371 2.2E-147 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 371 44.102 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 SPSF3K_RS10895 a1120e7e9258117de169308c75fef0d5 371 Gene3D G3DSA:3.40.50.300 1 80 1.4E-7 T 29-03-2018 SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 SUPERFAMILY SSF55326 195 231 4.88E-33 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 SUPERFAMILY SSF55326 289 429 4.88E-33 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 SMART SM01211 976 1238 3.5E-106 T 29-03-2018 SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 Gene3D G3DSA:3.90.650.10 422 607 1.6E-27 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 Pfam PF02769 AIR synthase related protein, C-terminal domain 439 590 1.7E-23 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 976 1238 1.3E-80 T 29-03-2018 SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 TIGRFAM TIGR01857 FGAM-synthase: phosphoribosylformylglycinamidine synthase 3 1238 0.0 T 29-03-2018 IPR010141 Phosphoribosylformylglycinamidine synthase, FGAM SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 Gene3D G3DSA:3.30.1330.10 620 809 5.4E-16 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 Gene3D G3DSA:3.40.50.880 975 1239 7.8E-24 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 SUPERFAMILY SSF56042 440 606 6.98E-37 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 Gene3D G3DSA:3.30.1330.10 205 421 5.2E-47 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 SUPERFAMILY SSF56042 813 959 1.15E-9 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 SUPERFAMILY SSF52317 974 1238 2.5E-64 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 Gene3D G3DSA:3.90.650.10 816 968 0.0015 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SPSF3K_RS10625 dd49d78834fd2ae34ddb85b9749255d4 1241 SUPERFAMILY SSF55326 630 805 6.54E-33 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SPSF3K_RS04865 eba0cf44b88b887cc84a829282a73333 377 SUPERFAMILY SSF51161 282 371 1.21E-12 T 29-03-2018 IPR011004 Trimeric LpxA-like SPSF3K_RS04865 eba0cf44b88b887cc84a829282a73333 377 Gene3D G3DSA:3.90.550.10 8 254 2.3E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS04865 eba0cf44b88b887cc84a829282a73333 377 Gene3D G3DSA:2.160.10.10 255 375 8.3E-13 T 29-03-2018 SPSF3K_RS04865 eba0cf44b88b887cc84a829282a73333 377 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 5 371 8.7E-129 T 29-03-2018 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 SPSF3K_RS04865 eba0cf44b88b887cc84a829282a73333 377 Pfam PF00483 Nucleotidyl transferase 22 256 2.5E-12 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SPSF3K_RS04865 eba0cf44b88b887cc84a829282a73333 377 SUPERFAMILY SSF53448 22 259 9.85E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS04865 eba0cf44b88b887cc84a829282a73333 377 SUPERFAMILY SSF53448 320 336 9.85E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 Pfam PF03358 NADPH-dependent FMN reductase 1 147 9.0E-33 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 Gene3D G3DSA:3.50.50.60 299 800 3.9E-63 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 SUPERFAMILY SSF51905 743 800 3.64E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 SUPERFAMILY SSF51905 405 605 3.64E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 SUPERFAMILY SSF51905 293 353 3.64E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 Gene3D G3DSA:3.40.50.360 1 191 1.8E-29 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 SUPERFAMILY SSF56425 613 744 9.42E-32 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 SMART SM00900 201 275 5.9E-17 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 SUPERFAMILY SSF52218 1 172 6.98E-37 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 423 795 1.2E-88 T 29-03-2018 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 Pfam PF00890 FAD binding domain 302 356 2.5E-13 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 Pfam PF00890 FAD binding domain 428 784 3.3E-58 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SPSF3K_RS06695 efe210c04b3000827b8119ec71389303 803 Pfam PF04205 FMN-binding domain 201 273 2.5E-10 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SPSF3K_RS07470 78a6ce47b905c11414a87b0538dddd42 643 Pfam PF00476 DNA polymerase family A 225 622 1.9E-21 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS07470 78a6ce47b905c11414a87b0538dddd42 643 Gene3D G3DSA:3.30.70.370 308 641 6.4E-32 T 29-03-2018 SPSF3K_RS07470 78a6ce47b905c11414a87b0538dddd42 643 ProSitePatterns PS00447 DNA polymerase family A signature. 437 456 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS07470 78a6ce47b905c11414a87b0538dddd42 643 Pfam PF13482 RNase_H superfamily 50 184 9.6E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS07470 78a6ce47b905c11414a87b0538dddd42 643 SMART SM00482 369 613 2.6E-21 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS07470 78a6ce47b905c11414a87b0538dddd42 643 SUPERFAMILY SSF56672 188 337 6.12E-79 T 29-03-2018 SPSF3K_RS07470 78a6ce47b905c11414a87b0538dddd42 643 SUPERFAMILY SSF56672 366 642 6.12E-79 T 29-03-2018 SPSF3K_RS07470 78a6ce47b905c11414a87b0538dddd42 643 Gene3D G3DSA:3.30.420.10 5 236 5.0E-8 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS06195 9b5d06cde37dc077c3056ce7f3414363 283 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 266 2.5E-58 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS06195 9b5d06cde37dc077c3056ce7f3414363 283 SUPERFAMILY SSF56784 1 270 4.51E-62 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS06195 9b5d06cde37dc077c3056ce7f3414363 283 ProSitePatterns PS01229 Hypothetical cof family signature 2. 220 242 - T 29-03-2018 SPSF3K_RS06195 9b5d06cde37dc077c3056ce7f3414363 283 Gene3D G3DSA:3.40.50.1000 1 276 2.5E-34 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS06195 9b5d06cde37dc077c3056ce7f3414363 283 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 266 2.8E-53 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS06195 9b5d06cde37dc077c3056ce7f3414363 283 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 239 4.2E-25 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 Pfam PF00342 Phosphoglucose isomerase 76 297 4.9E-16 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 Gene3D G3DSA:3.40.50.10490 1 54 2.7E-8 T 29-03-2018 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 Gene3D G3DSA:3.40.50.10490 225 418 2.6E-56 T 29-03-2018 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 SUPERFAMILY SSF53697 5 448 2.23E-132 T 29-03-2018 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 409 426 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 436 24.17 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 1.8E-23 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 1.8E-23 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 1.8E-23 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 1.8E-23 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 1.8E-23 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 1.8E-23 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS00855 cfa86a448f89ca7c202589a87349be71 449 Gene3D G3DSA:3.40.50.10490 55 224 3.2E-50 T 29-03-2018 SPSF3K_RS09215 da1bd80fdd13955ba74d9eca4bb0c4b3 271 SUPERFAMILY SSF56281 31 234 1.97E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS09215 da1bd80fdd13955ba74d9eca4bb0c4b3 271 Pfam PF12706 Beta-lactamase superfamily domain 49 229 8.0E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS09215 da1bd80fdd13955ba74d9eca4bb0c4b3 271 Gene3D G3DSA:3.60.15.10 3 268 8.3E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS07475 5f11bdca3ebcc60c412004197835c155 212 Pfam PF13392 HNH endonuclease 101 144 4.0E-13 T 29-03-2018 IPR003615 HNH nuclease SPSF3K_RS07475 5f11bdca3ebcc60c412004197835c155 212 Gene3D G3DSA:3.30.730.10 162 207 5.1E-8 T 29-03-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 SPSF3K_RS07475 5f11bdca3ebcc60c412004197835c155 212 Pfam PF00847 AP2 domain 162 201 3.0E-5 T 29-03-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 SPSF3K_RS07475 5f11bdca3ebcc60c412004197835c155 212 SUPERFAMILY SSF54171 162 205 2.62E-7 T 29-03-2018 IPR016177 DNA-binding domain GO:0003677 SPSF3K_RS07475 5f11bdca3ebcc60c412004197835c155 212 SUPERFAMILY SSF54060 35 149 1.53E-27 T 29-03-2018 SPSF3K_RS07475 5f11bdca3ebcc60c412004197835c155 212 Pfam PF07463 NUMOD4 motif 35 101 8.9E-16 T 29-03-2018 IPR010902 NUMOD4 GO:0016788 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 ProSitePatterns PS01166 RNA polymerases beta chain signature. 918 930 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 SUPERFAMILY SSF64484 382 1151 0.0 T 29-03-2018 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 SUPERFAMILY SSF64484 14 291 0.0 T 29-03-2018 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Pfam PF00562 RNA polymerase Rpb2, domain 6 680 1065 5.3E-162 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Gene3D G3DSA:2.40.270.10 838 1051 3.6E-78 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Gene3D G3DSA:2.40.270.10 748 837 4.2E-11 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1143 12.242 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Pfam PF04565 RNA polymerase Rpb2, domain 3 473 538 1.4E-28 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Pfam PF10385 RNA polymerase beta subunit external 1 domain 551 618 3.8E-21 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Gene3D G3DSA:3.90.1800.10 1068 1111 3.4E-11 T 29-03-2018 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Pfam PF04560 RNA polymerase Rpb2, domain 7 1067 1141 1.1E-25 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Pfam PF04561 RNA polymerase Rpb2, domain 2 363 414 3.5E-8 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 293 1.1E-23 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Gene3D G3DSA:2.40.50.100 676 747 3.9E-23 T 29-03-2018 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Pfam PF04563 RNA polymerase beta subunit 28 460 8.3E-29 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Gene3D G3DSA:3.90.1100.10 20 225 2.0E-55 T 29-03-2018 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Gene3D G3DSA:3.90.1100.10 610 675 5.1E-13 T 29-03-2018 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 Gene3D G3DSA:3.90.1100.10 278 609 1.3E-79 T 29-03-2018 SPSF3K_RS01920 a068d98e4c849abf4b1715abd6d3f6a4 1197 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 220 892 3.1E-290 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 327 589 4.4E-14 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 Gene3D G3DSA:3.20.20.80 283 592 4.9E-39 T 29-03-2018 SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 Gene3D G3DSA:2.60.120.260 1 178 1.5E-42 T 29-03-2018 IPR008979 Galactose-binding domain-like SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 SUPERFAMILY SSF51445 287 470 1.44E-58 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 SUPERFAMILY SSF51445 501 589 1.44E-58 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 SUPERFAMILY SSF49303 188 290 1.27E-8 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 Gene3D G3DSA:2.60.40.10 179 282 1.9E-10 T 29-03-2018 IPR013783 Immunoglobulin-like fold SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 SUPERFAMILY SSF49785 4 178 1.7E-46 T 29-03-2018 IPR008979 Galactose-binding domain-like SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 18 141 5.4E-14 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS02215 d8e4d67d3dd5b5bda94c53de4e87afe1 599 Pfam PF00703 Glycosyl hydrolases family 2 233 290 8.2E-7 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 Gene3D G3DSA:3.90.45.10 15 204 4.6E-50 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 SUPERFAMILY SSF56420 8 201 7.46E-58 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 PRINTS PR01576 Peptide deformylase signature 129 140 3.9E-31 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 PRINTS PR01576 Peptide deformylase signature 59 88 3.9E-31 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 PRINTS PR01576 Peptide deformylase signature 142 160 3.9E-31 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 PRINTS PR01576 Peptide deformylase signature 161 190 3.9E-31 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 PIRSF PIRSF004749 3 204 2.9E-45 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 Hamap MF_00163 Peptide deformylase [def]. 15 203 25.716 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 18 198 7.2E-39 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS02600 b1fdaa6edc991eb76e9180c908b7a1c6 204 Pfam PF01327 Polypeptide deformylase 17 191 1.4E-44 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS00295 4c5fcdcbd977801f0b3d723f6838ed53 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00295 4c5fcdcbd977801f0b3d723f6838ed53 49 SUPERFAMILY SSF57829 1 49 3.91E-15 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SPSF3K_RS00295 4c5fcdcbd977801f0b3d723f6838ed53 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.2E-16 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00295 4c5fcdcbd977801f0b3d723f6838ed53 49 Pfam PF00471 Ribosomal protein L33 3 49 1.1E-17 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00295 4c5fcdcbd977801f0b3d723f6838ed53 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 15.423 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS09970 f4f54916e7f35f4b8079dbcb5221b1b3 211 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 211 27.437 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SPSF3K_RS09970 f4f54916e7f35f4b8079dbcb5221b1b3 211 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 26 209 1.0E-55 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SPSF3K_RS09970 f4f54916e7f35f4b8079dbcb5221b1b3 211 Pfam PF02390 Putative methyltransferase 38 207 1.3E-47 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 SPSF3K_RS09970 f4f54916e7f35f4b8079dbcb5221b1b3 211 SUPERFAMILY SSF53335 33 209 1.52E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS09970 f4f54916e7f35f4b8079dbcb5221b1b3 211 Gene3D G3DSA:3.40.50.150 1 211 2.6E-35 T 29-03-2018 SPSF3K_RS08155 77b5bdeb324b29bdc483fcc6234da04e 309 Gene3D G3DSA:3.60.15.10 1 309 3.9E-55 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08155 77b5bdeb324b29bdc483fcc6234da04e 309 Pfam PF12706 Beta-lactamase superfamily domain 206 274 1.6E-6 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08155 77b5bdeb324b29bdc483fcc6234da04e 309 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 308 1.3E-107 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 SPSF3K_RS08155 77b5bdeb324b29bdc483fcc6234da04e 309 Hamap MF_01818 Ribonuclease BN [rbn]. 1 309 38.558 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 SPSF3K_RS08155 77b5bdeb324b29bdc483fcc6234da04e 309 SUPERFAMILY SSF56281 1 309 6.77E-77 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08155 77b5bdeb324b29bdc483fcc6234da04e 309 Pfam PF00753 Metallo-beta-lactamase superfamily 35 78 6.3E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 Pfam PF00271 Helicase conserved C-terminal domain 566 650 1.3E-9 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 TIGRFAM TIGR00595 priA: primosomal protein N' 279 788 8.0E-197 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 Gene3D G3DSA:3.40.50.300 237 442 3.8E-25 T 29-03-2018 SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 791 23.792 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 SUPERFAMILY SSF52540 235 438 3.83E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 SMART SM00487 252 448 9.5E-23 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 SMART SM00490 555 651 2.0E-9 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 SUPERFAMILY SSF52540 520 698 1.72E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 Gene3D G3DSA:3.40.50.300 453 686 2.2E-22 T 29-03-2018 SPSF3K_RS09660 d925ad480d8e08350fbae44a385128fc 792 Pfam PF04851 Type III restriction enzyme, res subunit 254 418 2.4E-18 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SPSF3K_RS04485 5762bac3cc1e1726f83ee555ac97cb47 247 SUPERFAMILY SSF51695 2 239 1.17E-61 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SPSF3K_RS04485 5762bac3cc1e1726f83ee555ac97cb47 247 Gene3D G3DSA:3.20.20.190 1 247 5.4E-61 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SPSF3K_RS04485 5762bac3cc1e1726f83ee555ac97cb47 247 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 233 2.7E-38 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 453 31.656 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 Gene3D G3DSA:3.40.1190.10 90 303 8.4E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 SUPERFAMILY SSF53623 100 302 1.1E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 Pfam PF08245 Mur ligase middle domain 105 284 3.1E-42 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 Gene3D G3DSA:3.40.1390.10 1 89 2.4E-23 T 29-03-2018 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 SUPERFAMILY SSF53244 305 452 5.26E-31 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 Gene3D G3DSA:3.90.190.20 304 456 3.4E-35 T 29-03-2018 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 Pfam PF01225 Mur ligase family, catalytic domain 28 72 1.1E-5 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 306 388 4.9E-9 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 452 3.5E-112 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 SPSF3K_RS08720 248cc8cae0fb09a16fb8d88936bd7fba 456 SUPERFAMILY SSF63418 2 96 1.57E-20 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SPSF3K_RS08525 7c3cbba150e5a12e151c0965456680eb 425 Gene3D G3DSA:3.20.20.370 216 425 4.0E-58 T 29-03-2018 SPSF3K_RS08525 7c3cbba150e5a12e151c0965456680eb 425 SUPERFAMILY SSF144015 32 235 3.53E-24 T 29-03-2018 SPSF3K_RS08525 7c3cbba150e5a12e151c0965456680eb 425 Pfam PF01522 Polysaccharide deacetylase 239 349 6.2E-34 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SPSF3K_RS08525 7c3cbba150e5a12e151c0965456680eb 425 SUPERFAMILY SSF88713 238 423 5.93E-63 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SPSF3K_RS02055 632df59d155efd460067bb61ceab8d79 290 PIRSF PIRSF005261 1 290 6.5E-72 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 SPSF3K_RS02055 632df59d155efd460067bb61ceab8d79 290 SUPERFAMILY SSF64397 1 239 2.49E-64 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 SPSF3K_RS02055 632df59d155efd460067bb61ceab8d79 290 Pfam PF01430 Hsp33 protein 2 278 8.3E-79 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 SPSF3K_RS02055 632df59d155efd460067bb61ceab8d79 290 Gene3D G3DSA:3.90.1280.10 233 286 1.9E-21 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 SPSF3K_RS02055 632df59d155efd460067bb61ceab8d79 290 Gene3D G3DSA:3.55.30.10 1 232 7.5E-64 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 SPSF3K_RS02055 632df59d155efd460067bb61ceab8d79 290 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 289 36.271 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 SPSF3K_RS02055 632df59d155efd460067bb61ceab8d79 290 SUPERFAMILY SSF118352 230 288 8.5E-19 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 130 3.3E-14 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 SUPERFAMILY SSF55021 350 415 7.63E-9 T 29-03-2018 SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 SUPERFAMILY SSF51735 3 159 4.69E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 Pfam PF01842 ACT domain 352 414 1.9E-7 T 29-03-2018 IPR002912 ACT domain SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 Pfam PF00742 Homoserine dehydrogenase 138 316 1.3E-63 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 PIRSF PIRSF000098 1 428 1.6E-164 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 Gene3D G3DSA:3.40.50.720 1 158 4.4E-28 T 29-03-2018 SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 Gene3D G3DSA:3.30.70.260 347 419 6.5E-11 T 29-03-2018 SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 SUPERFAMILY SSF55347 138 303 2.16E-52 T 29-03-2018 SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 SPSF3K_RS06080 05da711afd22cb38e5c50923e358982e 428 Gene3D G3DSA:3.30.360.10 159 299 2.2E-52 T 29-03-2018 SPSF3K_RS06320 1b45ff9c480377865ee7757efd834444 242 Pfam PF00005 ABC transporter 17 163 1.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS06320 1b45ff9c480377865ee7757efd834444 242 Gene3D G3DSA:3.40.50.300 1 242 1.9E-71 T 29-03-2018 SPSF3K_RS06320 1b45ff9c480377865ee7757efd834444 242 SUPERFAMILY SSF52540 1 236 7.14E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06320 1b45ff9c480377865ee7757efd834444 242 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS06320 1b45ff9c480377865ee7757efd834444 242 SMART SM00382 26 221 7.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02375 ef09c019a7606ee8961d6237dbd0290e 293 Pfam PF03466 LysR substrate binding domain 119 282 2.2E-11 T 29-03-2018 IPR005119 LysR, substrate-binding SPSF3K_RS02375 ef09c019a7606ee8961d6237dbd0290e 293 Gene3D G3DSA:3.40.190.10 94 180 1.6E-4 T 29-03-2018 SPSF3K_RS02375 ef09c019a7606ee8961d6237dbd0290e 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 5.4E-12 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS02375 ef09c019a7606ee8961d6237dbd0290e 293 Gene3D G3DSA:3.40.190.10 181 263 7.1E-8 T 29-03-2018 SPSF3K_RS02375 ef09c019a7606ee8961d6237dbd0290e 293 Gene3D G3DSA:1.10.10.10 1 89 1.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02375 ef09c019a7606ee8961d6237dbd0290e 293 SUPERFAMILY SSF53850 120 289 2.17E-15 T 29-03-2018 SPSF3K_RS02375 ef09c019a7606ee8961d6237dbd0290e 293 SUPERFAMILY SSF46785 1 85 3.76E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00490 8c88f44083251acd1d6cc36a0ab5d16b 89 PIRSF PIRSF037258 1 87 6.8E-44 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 SPSF3K_RS00490 8c88f44083251acd1d6cc36a0ab5d16b 89 Hamap MF_01507 UPF0297 protein . 1 84 27.355 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 SPSF3K_RS00490 8c88f44083251acd1d6cc36a0ab5d16b 89 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 3.4E-36 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 SPSF3K_RS07955 44699bff8887f8d9d8f15ce7634fd4cc 376 SMART SM00729 5 221 2.7E-58 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SPSF3K_RS07955 44699bff8887f8d9d8f15ce7634fd4cc 376 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 364 2.5E-111 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 SPSF3K_RS07955 44699bff8887f8d9d8f15ce7634fd4cc 376 Pfam PF04055 Radical SAM superfamily 10 173 5.2E-22 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SPSF3K_RS07955 44699bff8887f8d9d8f15ce7634fd4cc 376 Pfam PF06969 HemN C-terminal domain 299 364 4.1E-16 T 29-03-2018 IPR010723 HemN, C-terminal SPSF3K_RS07955 44699bff8887f8d9d8f15ce7634fd4cc 376 SUPERFAMILY SSF102114 5 374 6.28E-113 T 29-03-2018 SPSF3K_RS07955 44699bff8887f8d9d8f15ce7634fd4cc 376 Gene3D G3DSA:3.20.20.70 7 317 1.1E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS03675 64b13a647a8f348a6d565b790c33cb6f 182 SUPERFAMILY SSF55729 1 153 4.69E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS03675 64b13a647a8f348a6d565b790c33cb6f 182 Pfam PF00583 Acetyltransferase (GNAT) family 31 144 3.5E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS03675 64b13a647a8f348a6d565b790c33cb6f 182 Gene3D G3DSA:3.40.630.30 1 180 1.9E-21 T 29-03-2018 SPSF3K_RS03080 833de62e5bec6105f33c3caa85c5cb48 314 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS03080 833de62e5bec6105f33c3caa85c5cb48 314 SUPERFAMILY SSF52540 5 250 1.17E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03080 833de62e5bec6105f33c3caa85c5cb48 314 Gene3D G3DSA:3.40.50.300 2 314 1.5E-73 T 29-03-2018 SPSF3K_RS03080 833de62e5bec6105f33c3caa85c5cb48 314 Pfam PF00005 ABC transporter 25 178 1.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS03080 833de62e5bec6105f33c3caa85c5cb48 314 SMART SM00382 34 228 1.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS03080 833de62e5bec6105f33c3caa85c5cb48 314 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 262 1.2E-6 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 SUPERFAMILY SSF51905 7 68 7.73E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 SUPERFAMILY SSF51905 99 262 7.73E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 Pfam PF01134 Glucose inhibited division protein A 10 402 1.3E-164 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 7 627 41.265 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 162 1.8E-6 T 29-03-2018 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.8E-6 T 29-03-2018 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 Pfam PF13932 GidA associated domain 404 619 5.2E-74 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 SMART SM01228 549 620 3.9E-41 T 29-03-2018 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 371 394 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 Gene3D G3DSA:3.50.50.60 7 267 4.4E-66 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 2.2E-5 T 29-03-2018 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.2E-5 T 29-03-2018 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 9 623 5.3E-273 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 SPSF3K_RS00135 554f9772639902a9709062f004e1dcde 632 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 276 290 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 SPSF3K_RS01160 02fbef825a177a9aa5a154988918f39e 210 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 14 204 3.0E-51 T 29-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 SPSF3K_RS01160 02fbef825a177a9aa5a154988918f39e 210 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 141 200 2.7E-9 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 SPSF3K_RS01160 02fbef825a177a9aa5a154988918f39e 210 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 19 110 7.1E-16 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 SPSF3K_RS01160 02fbef825a177a9aa5a154988918f39e 210 Gene3D G3DSA:3.40.50.10240 5 102 8.3E-19 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 SPSF3K_RS01160 02fbef825a177a9aa5a154988918f39e 210 Gene3D G3DSA:2.60.120.320 103 210 1.4E-17 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 SPSF3K_RS01160 02fbef825a177a9aa5a154988918f39e 210 SUPERFAMILY SSF63999 1 126 6.67E-31 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 SPSF3K_RS01160 02fbef825a177a9aa5a154988918f39e 210 SMART SM00983 139 202 5.0E-19 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 SPSF3K_RS09110 e9f8184b1f09f1938090fabddc4a1bcc 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 119 1.8E-20 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SPSF3K_RS09110 e9f8184b1f09f1938090fabddc4a1bcc 320 Gene3D G3DSA:3.40.50.720 1 135 2.8E-32 T 29-03-2018 SPSF3K_RS09110 e9f8184b1f09f1938090fabddc4a1bcc 320 SUPERFAMILY SSF51735 3 153 1.71E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS09110 e9f8184b1f09f1938090fabddc4a1bcc 320 Gene3D G3DSA:3.30.360.10 136 319 3.2E-23 T 29-03-2018 SPSF3K_RS09110 e9f8184b1f09f1938090fabddc4a1bcc 320 SUPERFAMILY SSF55347 129 289 6.05E-27 T 29-03-2018 SPSF3K_RS09990 3772bf7d904e547d6eb2414095516924 139 Gene3D G3DSA:3.30.428.10 1 137 4.5E-37 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SPSF3K_RS09990 3772bf7d904e547d6eb2414095516924 139 Pfam PF01230 HIT domain 12 106 5.3E-26 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SPSF3K_RS09990 3772bf7d904e547d6eb2414095516924 139 PRINTS PR00332 Histidine triad family signature 93 103 7.7E-16 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SPSF3K_RS09990 3772bf7d904e547d6eb2414095516924 139 PRINTS PR00332 Histidine triad family signature 5 21 7.7E-16 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SPSF3K_RS09990 3772bf7d904e547d6eb2414095516924 139 PRINTS PR00332 Histidine triad family signature 26 44 7.7E-16 T 29-03-2018 IPR001310 Histidine triad (HIT) protein SPSF3K_RS09990 3772bf7d904e547d6eb2414095516924 139 SUPERFAMILY SSF54197 2 134 3.87E-40 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 SPSF3K_RS04030 761bcd1abfd440230074ebc32859278e 104 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 9 101 2.4E-33 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 SPSF3K_RS04030 761bcd1abfd440230074ebc32859278e 104 Gene3D G3DSA:1.20.58.80 4 102 8.0E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 SPSF3K_RS04030 761bcd1abfd440230074ebc32859278e 104 SUPERFAMILY SSF46973 1 102 1.44E-34 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 SPSF3K_RS04030 761bcd1abfd440230074ebc32859278e 104 PIRSF PIRSF000699 1 104 2.5E-36 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 SPSF3K_RS09790 5411217a48302a8be57701c6976d51bd 107 Hamap MF_00910 Cell division protein FtsL [ftsL]. 25 107 13.401 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 SPSF3K_RS09790 5411217a48302a8be57701c6976d51bd 107 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 25 106 3.0E-17 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 SPSF3K_RS09790 5411217a48302a8be57701c6976d51bd 107 Gene3D G3DSA:1.20.5.730 34 89 1.3E-4 T 29-03-2018 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 288 3.4E-27 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 SMART SM00984 315 400 1.3E-9 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 PIRSF PIRSF000124 1 401 2.8E-131 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 SUPERFAMILY SSF52413 299 399 5.1E-22 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 Gene3D G3DSA:3.40.50.720 222 392 1.0E-42 T 29-03-2018 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 SUPERFAMILY SSF51735 2 199 9.17E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 Gene3D G3DSA:3.40.50.720 2 200 2.2E-45 T 29-03-2018 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 PIRSF PIRSF500134 1 380 5.4E-116 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 SUPERFAMILY SSF48179 199 294 5.33E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 Gene3D G3DSA:1.20.5.100 201 221 7.5E-15 T 29-03-2018 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 171 9.8E-31 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS00905 4ee8764c6851316d72c276c6cbc4069a 401 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 386 5.0E-93 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS07875 2e77bd3f6960d784e619b207c256e8f7 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 SPSF3K_RS07875 2e77bd3f6960d784e619b207c256e8f7 345 Gene3D G3DSA:3.90.180.10 1 161 3.8E-39 T 29-03-2018 SPSF3K_RS07875 2e77bd3f6960d784e619b207c256e8f7 345 SMART SM00829 10 342 0.0027 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SPSF3K_RS07875 2e77bd3f6960d784e619b207c256e8f7 345 Pfam PF00107 Zinc-binding dehydrogenase 178 291 5.6E-21 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SPSF3K_RS07875 2e77bd3f6960d784e619b207c256e8f7 345 SUPERFAMILY SSF50129 1 166 3.5E-45 T 29-03-2018 IPR011032 GroES-like SPSF3K_RS07875 2e77bd3f6960d784e619b207c256e8f7 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 125 2.1E-23 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SPSF3K_RS07875 2e77bd3f6960d784e619b207c256e8f7 345 Gene3D G3DSA:3.40.50.10730 162 294 1.2E-26 T 29-03-2018 SPSF3K_RS07875 2e77bd3f6960d784e619b207c256e8f7 345 SUPERFAMILY SSF51735 147 307 9.41E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS10400 e8bb84c70d73394868de5f244268690b 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 112 1.3E-51 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10400 e8bb84c70d73394868de5f244268690b 121 Gene3D G3DSA:1.10.8.50 1 66 3.0E-23 T 29-03-2018 SPSF3K_RS10400 e8bb84c70d73394868de5f244268690b 121 Gene3D G3DSA:4.10.910.10 86 121 1.5E-25 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10400 e8bb84c70d73394868de5f244268690b 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.07 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10400 e8bb84c70d73394868de5f244268690b 121 PIRSF PIRSF002134 1 121 4.9E-42 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10400 e8bb84c70d73394868de5f244268690b 121 Pfam PF00416 Ribosomal protein S13/S18 59 108 2.1E-18 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10400 e8bb84c70d73394868de5f244268690b 121 SUPERFAMILY SSF46946 2 112 1.35E-44 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SPSF3K_RS10400 e8bb84c70d73394868de5f244268690b 121 Gene3D G3DSA:4.10.910.10 67 85 1.1E-18 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10400 e8bb84c70d73394868de5f244268690b 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS01345 f66a06c381a6a1eda9ee503910424b19 325 Gene3D G3DSA:3.40.50.720 1 142 3.8E-28 T 29-03-2018 SPSF3K_RS01345 f66a06c381a6a1eda9ee503910424b19 325 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 118 8.1E-21 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SPSF3K_RS01345 f66a06c381a6a1eda9ee503910424b19 325 Gene3D G3DSA:3.30.360.10 143 319 1.1E-13 T 29-03-2018 SPSF3K_RS01345 f66a06c381a6a1eda9ee503910424b19 325 SUPERFAMILY SSF51735 2 153 1.39E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS01345 f66a06c381a6a1eda9ee503910424b19 325 SUPERFAMILY SSF55347 130 281 4.58E-16 T 29-03-2018 SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 Gene3D G3DSA:2.40.50.140 129 184 1.5E-23 T 29-03-2018 SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 SMART SM00841 129 184 1.7E-29 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 5.0E-24 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 PIRSF PIRSF005901 1 185 1.6E-63 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 47.38 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 SUPERFAMILY SSF50249 128 185 9.59E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 Gene3D G3DSA:2.30.30.30 2 61 1.0E-21 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 SUPERFAMILY SSF50249 64 126 7.28E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 Gene3D G3DSA:2.40.50.140 65 126 2.8E-18 T 29-03-2018 SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 5.9E-68 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 8.1E-23 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 SUPERFAMILY SSF50104 1 63 4.99E-19 T 29-03-2018 IPR008991 Translation protein SH3-like domain SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 SMART SM01185 67 121 5.0E-19 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SPSF3K_RS01665 987559e58d20135c5364901343d3a734 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 6.9E-16 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 SPSF3K_RS06255 dffce606e0cbc5bde06f06ae0cf0a192 375 SUPERFAMILY SSF53383 3 373 5.26E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS06255 dffce606e0cbc5bde06f06ae0cf0a192 375 PIRSF PIRSF005572 3 375 6.7E-109 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SPSF3K_RS06255 dffce606e0cbc5bde06f06ae0cf0a192 375 Gene3D G3DSA:3.40.640.10 14 243 1.9E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS06255 dffce606e0cbc5bde06f06ae0cf0a192 375 Pfam PF00266 Aminotransferase class-V 6 364 7.2E-74 T 29-03-2018 IPR000192 Aminotransferase class V domain SPSF3K_RS06255 dffce606e0cbc5bde06f06ae0cf0a192 375 Gene3D G3DSA:3.90.1150.10 244 372 2.1E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS08210 628406f828d078b8eaeda66b026db4b0 755 PIRSF PIRSF000460 1 755 2.1E-187 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SPSF3K_RS08210 628406f828d078b8eaeda66b026db4b0 755 Gene3D G3DSA:3.40.50.2000 1 418 1.4E-129 T 29-03-2018 SPSF3K_RS08210 628406f828d078b8eaeda66b026db4b0 755 Gene3D G3DSA:3.40.50.2000 419 738 3.5E-111 T 29-03-2018 SPSF3K_RS08210 628406f828d078b8eaeda66b026db4b0 755 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 596 608 - T 29-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SPSF3K_RS08210 628406f828d078b8eaeda66b026db4b0 755 Pfam PF00343 Carbohydrate phosphorylase 79 752 2.8E-247 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SPSF3K_RS08210 628406f828d078b8eaeda66b026db4b0 755 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 4 752 6.8E-260 T 29-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 SPSF3K_RS08210 628406f828d078b8eaeda66b026db4b0 755 SUPERFAMILY SSF53756 4 753 1.49E-244 T 29-03-2018 SPSF3K_RS08985 d30e119bb8a679e4eda58041bd831202 166 Pfam PF04892 VanZ like family 23 159 5.1E-20 T 29-03-2018 IPR006976 VanZ-like SPSF3K_RS02255 093f8f1a95d236042a4214e04324f5b8 248 SUPERFAMILY SSF56784 5 218 4.31E-26 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02255 093f8f1a95d236042a4214e04324f5b8 248 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 215 1.2E-11 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS02255 093f8f1a95d236042a4214e04324f5b8 248 Gene3D G3DSA:3.40.50.1000 5 248 4.3E-20 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02255 093f8f1a95d236042a4214e04324f5b8 248 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 218 3.0E-22 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07590 8bce0ff3538f65eb8831d4242e483dee 340 SUPERFAMILY SSF56752 4 336 3.92E-100 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SPSF3K_RS07590 8bce0ff3538f65eb8831d4242e483dee 340 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 30 339 3.4E-135 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 SPSF3K_RS07590 8bce0ff3538f65eb8831d4242e483dee 340 Gene3D G3DSA:3.30.470.10 1 161 3.6E-50 T 29-03-2018 SPSF3K_RS07590 8bce0ff3538f65eb8831d4242e483dee 340 Gene3D G3DSA:3.20.10.10 162 322 2.4E-39 T 29-03-2018 SPSF3K_RS07590 8bce0ff3538f65eb8831d4242e483dee 340 ProSitePatterns PS00770 Aminotransferases class-IV signature. 220 249 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 SPSF3K_RS07590 8bce0ff3538f65eb8831d4242e483dee 340 Pfam PF01063 Amino-transferase class IV 55 293 1.3E-33 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 SPSF3K_RS07590 8bce0ff3538f65eb8831d4242e483dee 340 PIRSF PIRSF006468 2 340 1.2E-116 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 SPSF3K_RS07035 d1538468763033bdcd0fd85699477144 77 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 77 13.245 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS07035 d1538468763033bdcd0fd85699477144 77 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 76 8.0E-23 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS07035 d1538468763033bdcd0fd85699477144 77 SUPERFAMILY SSF46992 3 76 1.44E-22 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS07035 d1538468763033bdcd0fd85699477144 77 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 76 6.9E-20 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS07035 d1538468763033bdcd0fd85699477144 77 Gene3D G3DSA:1.20.58.110 1 77 7.6E-22 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS07035 d1538468763033bdcd0fd85699477144 77 Pfam PF01649 Ribosomal protein S20 2 76 4.8E-22 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS05135 1b9daafeae02ba9f2e0ffaad3ac3b453 226 Pfam PF01487 Type I 3-dehydroquinase 5 218 2.9E-51 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SPSF3K_RS05135 1b9daafeae02ba9f2e0ffaad3ac3b453 226 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 2 222 35.962 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SPSF3K_RS05135 1b9daafeae02ba9f2e0ffaad3ac3b453 226 SUPERFAMILY SSF51569 2 222 6.96E-62 T 29-03-2018 SPSF3K_RS05135 1b9daafeae02ba9f2e0ffaad3ac3b453 226 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 3 218 4.9E-47 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SPSF3K_RS05135 1b9daafeae02ba9f2e0ffaad3ac3b453 226 Gene3D G3DSA:3.20.20.70 1 225 2.5E-63 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS08990 5c3d7d3207226cfaec39a479b8661ef2 361 Pfam PF04055 Radical SAM superfamily 105 272 1.4E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SPSF3K_RS08990 5c3d7d3207226cfaec39a479b8661ef2 361 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 2 349 70.198 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS08990 5c3d7d3207226cfaec39a479b8661ef2 361 Pfam PF13394 4Fe-4S single cluster domain 110 204 4.0E-8 T 29-03-2018 SPSF3K_RS08990 5c3d7d3207226cfaec39a479b8661ef2 361 PIRSF PIRSF006004 1 361 8.0E-137 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS08990 5c3d7d3207226cfaec39a479b8661ef2 361 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 1 350 8.6E-133 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS08990 5c3d7d3207226cfaec39a479b8661ef2 361 Gene3D G3DSA:3.20.20.70 9 350 6.6E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS08990 5c3d7d3207226cfaec39a479b8661ef2 361 SUPERFAMILY SSF102114 97 307 1.01E-13 T 29-03-2018 SPSF3K_RS03685 332ee83436f46214071bd1df13fc3e99 166 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 80 157 1.6E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SPSF3K_RS03685 332ee83436f46214071bd1df13fc3e99 166 SUPERFAMILY SSF46767 79 159 7.32E-27 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SPSF3K_RS03685 332ee83436f46214071bd1df13fc3e99 166 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 80 158 3.6E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 SPSF3K_RS03685 332ee83436f46214071bd1df13fc3e99 166 Gene3D G3DSA:1.10.10.10 76 166 5.8E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03685 332ee83436f46214071bd1df13fc3e99 166 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SPSF3K_RS03685 332ee83436f46214071bd1df13fc3e99 166 SUPERFAMILY SSF53155 3 83 7.85E-14 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 SPSF3K_RS03685 332ee83436f46214071bd1df13fc3e99 166 Gene3D G3DSA:3.30.160.70 1 69 1.9E-16 T 29-03-2018 SPSF3K_RS06640 aeb05823186af0a5ae32b542309ef13f 133 Pfam PF06803 Protein of unknown function (DUF1232) 38 73 3.1E-13 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 178.557 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 Pfam PF00871 Acetokinase family 4 389 2.2E-146 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 Gene3D G3DSA:3.30.420.40 195 397 1.0E-72 T 29-03-2018 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 TIGRFAM TIGR00016 ackA: acetate kinase 2 395 6.5E-150 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 Gene3D G3DSA:3.30.420.40 3 194 4.5E-71 T 29-03-2018 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 PIRSF PIRSF000722 1 397 4.1E-141 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 SUPERFAMILY SSF53067 1 194 1.75E-64 T 29-03-2018 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 SUPERFAMILY SSF53067 156 394 2.16E-84 T 29-03-2018 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 PRINTS PR00471 Acetate kinase family signature 202 223 2.4E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 PRINTS PR00471 Acetate kinase family signature 376 388 2.4E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 PRINTS PR00471 Acetate kinase family signature 4 15 2.4E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 PRINTS PR00471 Acetate kinase family signature 301 314 2.4E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 PRINTS PR00471 Acetate kinase family signature 323 339 2.4E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS01975 e9a464b07f448181437c225c9413ac50 397 PRINTS PR00471 Acetate kinase family signature 172 185 2.4E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 SMART SM00382 145 278 3.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 Gene3D G3DSA:1.10.8.60 281 351 1.3E-17 T 29-03-2018 SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 SUPERFAMILY SSF52540 112 326 2.82E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 Gene3D G3DSA:3.40.50.300 110 279 2.1E-21 T 29-03-2018 SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 Pfam PF00308 Bacterial dnaA protein 113 332 1.6E-84 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 9 452 2.8E-153 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 SUPERFAMILY SSF48295 356 453 1.05E-34 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 Gene3D G3DSA:1.10.1750.10 355 453 1.6E-34 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 SMART SM00760 362 431 3.9E-40 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 6 453 30.419 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 363 431 4.3E-31 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 246 273 1.5E-48 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 412 431 1.5E-48 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 210 224 1.5E-48 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 178 192 1.5E-48 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 146 166 1.5E-48 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like SPSF3K_RS10915 89359819e99b6a7812a49043d8ee78d7 453 ProSitePatterns PS01008 DnaA protein signature. 412 431 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SPSF3K_RS10880 97ce51ca73367f892f0682ef9b53ec04 503 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 350 487 1.1E-16 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain SPSF3K_RS10880 97ce51ca73367f892f0682ef9b53ec04 503 Pfam PF01943 Polysaccharide biosynthesis protein 14 299 2.2E-24 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 Pfam PF01039 Carboxyl transferase domain 67 244 6.5E-18 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 286 39.334 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 21 284 1.7E-110 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 256 265 9.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 205 222 9.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 168 186 9.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 234 245 9.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 148 9.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 Gene3D G3DSA:3.90.226.10 21 288 4.0E-69 T 29-03-2018 SPSF3K_RS10065 2a81fac7a1ef4d1753f2e919e60b6e08 288 SUPERFAMILY SSF52096 34 284 1.53E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SPSF3K_RS09610 ea4bbe63791f854521c85346d41baf17 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 294 5.6E-65 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SPSF3K_RS09610 ea4bbe63791f854521c85346d41baf17 309 SUPERFAMILY SSF53686 3 305 1.7E-96 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SPSF3K_RS09610 ea4bbe63791f854521c85346d41baf17 309 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 305 2.4E-131 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 SPSF3K_RS09610 ea4bbe63791f854521c85346d41baf17 309 Gene3D G3DSA:3.40.50.1100 143 308 1.3E-48 T 29-03-2018 SPSF3K_RS09610 ea4bbe63791f854521c85346d41baf17 309 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SPSF3K_RS09610 ea4bbe63791f854521c85346d41baf17 309 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 305 1.2E-124 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 SPSF3K_RS09610 ea4bbe63791f854521c85346d41baf17 309 Gene3D G3DSA:3.40.50.1100 39 142 6.3E-40 T 29-03-2018 SPSF3K_RS01310 7e33c6374ebb8b9487aefdea31dad301 281 Gene3D G3DSA:2.60.120.10 135 281 4.5E-47 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS01310 7e33c6374ebb8b9487aefdea31dad301 281 Gene3D G3DSA:2.60.120.520 29 134 3.1E-44 T 29-03-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 SPSF3K_RS01310 7e33c6374ebb8b9487aefdea31dad301 281 Pfam PF04962 KduI/IolB family 75 273 4.9E-28 T 29-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 SPSF3K_RS01310 7e33c6374ebb8b9487aefdea31dad301 281 SUPERFAMILY SSF51182 7 265 7.12E-98 T 29-03-2018 IPR011051 RmlC-like cupin domain SPSF3K_RS01310 7e33c6374ebb8b9487aefdea31dad301 281 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 6 281 51.778 T 29-03-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 SPSF3K_RS01310 7e33c6374ebb8b9487aefdea31dad301 281 PIRSF PIRSF006625 6 281 2.3E-124 T 29-03-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 Pfam PF03714 Bacterial pullanase-associated domain 5 99 4.9E-13 T 29-03-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 Gene3D G3DSA:3.20.20.80 252 689 6.2E-75 T 29-03-2018 SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 137 229 7.8E-9 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 Gene3D G3DSA:2.60.40.10 134 250 4.9E-24 T 29-03-2018 IPR013783 Immunoglobulin-like fold SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 Gene3D G3DSA:2.60.40.1110 2 98 9.1E-14 T 29-03-2018 SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 127 722 2.5E-230 T 29-03-2018 IPR011840 Pullulanase, type I SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 Pfam PF00128 Alpha amylase, catalytic domain 314 403 1.2E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 Pfam PF00128 Alpha amylase, catalytic domain 435 624 3.9E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 SUPERFAMILY SSF51445 258 687 5.02E-104 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 SUPERFAMILY SSF49452 3 101 2.75E-21 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 SMART SM00642 274 681 2.4E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS04845 b2c1250bab4e6360fe7bbee62b9bdbfb 770 SUPERFAMILY SSF81296 130 246 1.04E-19 T 29-03-2018 IPR014756 Immunoglobulin E-set SPSF3K_RS07460 659600549eb74d7248ad1767fc06b32a 91 Pfam PF08774 VRR-NUC domain 26 76 1.0E-6 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 SPSF3K_RS07460 659600549eb74d7248ad1767fc06b32a 91 SMART SM00990 2 78 4.6E-22 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 SPSF3K_RS04675 45805819fc82b6cfc4f9ce4698e71005 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 32.162 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS04675 45805819fc82b6cfc4f9ce4698e71005 115 SUPERFAMILY SSF50104 1 114 2.21E-46 T 29-03-2018 IPR008991 Translation protein SH3-like domain SPSF3K_RS04675 45805819fc82b6cfc4f9ce4698e71005 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.1E-42 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS04675 45805819fc82b6cfc4f9ce4698e71005 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.1E-42 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS04675 45805819fc82b6cfc4f9ce4698e71005 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.1E-42 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS04675 45805819fc82b6cfc4f9ce4698e71005 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS04675 45805819fc82b6cfc4f9ce4698e71005 115 Pfam PF01245 Ribosomal protein L19 4 112 3.7E-51 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS04675 45805819fc82b6cfc4f9ce4698e71005 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 113 1.3E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS04675 45805819fc82b6cfc4f9ce4698e71005 115 PIRSF PIRSF002191 1 115 5.7E-50 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 1.1E-32 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 1.1E-32 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 PRINTS PR01041 Methionyl-tRNA synthetase signature 235 246 1.1E-32 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 PRINTS PR01041 Methionyl-tRNA synthetase signature 361 372 1.1E-32 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 1.1E-32 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 PRINTS PR01041 Methionyl-tRNA synthetase signature 269 284 1.1E-32 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 SUPERFAMILY SSF47323 363 578 3.74E-44 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 Pfam PF09334 tRNA synthetases class I (M) 7 373 1.7E-110 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 Hamap MF_01228 Methionine--tRNA ligase [metG]. 3 520 48.844 T 29-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 SUPERFAMILY SSF52374 3 364 6.17E-102 T 29-03-2018 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 SUPERFAMILY SSF50249 566 665 4.16E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 537 667 2.8E-35 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 Gene3D G3DSA:2.40.50.140 557 668 1.7E-24 T 29-03-2018 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 Gene3D G3DSA:3.40.50.620 4 357 3.1E-90 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 Pfam PF01588 Putative tRNA binding domain 571 665 4.5E-21 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 521 6.1E-167 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPSF3K_RS03745 d35c7300e2b30e5fa1132d2838e23352 668 Gene3D G3DSA:1.10.730.10 358 523 4.6E-37 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 SMART SM00471 347 453 3.5E-12 T 29-03-2018 IPR003607 HD/PDEase domain SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 Pfam PF00013 KH domain 228 284 1.2E-7 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 SMART SM00322 223 290 1.6E-8 T 29-03-2018 IPR004087 K Homology domain GO:0003676 SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 TIGRFAM TIGR00277 HDIG: HDIG domain 347 424 3.9E-23 T 29-03-2018 IPR006675 HDIG domain SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 SUPERFAMILY SSF54791 223 319 7.44E-17 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 SUPERFAMILY SSF109604 331 482 7.18E-27 T 29-03-2018 SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 5 535 3.0E-230 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 Hamap MF_00335 Ribonuclease Y [rny]. 2 535 24.801 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 Gene3D G3DSA:1.10.3210.10 341 517 8.6E-22 T 29-03-2018 SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 Gene3D G3DSA:3.30.1370.10 217 321 4.1E-12 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 Pfam PF01966 HD domain 352 442 4.1E-17 T 29-03-2018 IPR006674 HD domain SPSF3K_RS09675 f1b8c556e622a331a5472347f0652dce 535 Pfam PF12072 Domain of unknown function (DUF3552) 3 220 7.5E-41 T 29-03-2018 IPR022711 Ribonuclease Y, N-terminal SPSF3K_RS03295 167c58aea54f3b5ac1958ca34697ef44 310 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 60 248 6.0E-44 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SPSF3K_RS03295 167c58aea54f3b5ac1958ca34697ef44 310 Pfam PF02096 60Kd inner membrane protein 60 247 1.4E-38 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPSF3K_RS03295 167c58aea54f3b5ac1958ca34697ef44 310 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 5 252 27.567 T 29-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes SPSF3K_RS04650 6507f83d90beea5af82a1641d0a8b3e6 259 Gene3D G3DSA:1.20.1050.10 139 257 6.2E-24 T 29-03-2018 SPSF3K_RS04650 6507f83d90beea5af82a1641d0a8b3e6 259 SUPERFAMILY SSF47616 118 253 8.49E-28 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like SPSF3K_RS04650 6507f83d90beea5af82a1641d0a8b3e6 259 Gene3D G3DSA:3.40.30.10 40 138 6.5E-20 T 29-03-2018 SPSF3K_RS04650 6507f83d90beea5af82a1641d0a8b3e6 259 Pfam PF13410 Glutathione S-transferase, C-terminal domain 174 238 2.6E-9 T 29-03-2018 SPSF3K_RS04650 6507f83d90beea5af82a1641d0a8b3e6 259 Pfam PF13409 Glutathione S-transferase, N-terminal domain 77 121 1.1E-5 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 SPSF3K_RS04650 6507f83d90beea5af82a1641d0a8b3e6 259 SUPERFAMILY SSF52833 34 124 1.9E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS07130 4f9715ac42aa7ad5e0f8003b1374a40b 233 SMART SM00382 32 215 1.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS07130 4f9715ac42aa7ad5e0f8003b1374a40b 233 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS07130 4f9715ac42aa7ad5e0f8003b1374a40b 233 Pfam PF00005 ABC transporter 24 166 5.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS07130 4f9715ac42aa7ad5e0f8003b1374a40b 233 SUPERFAMILY SSF52540 4 223 1.05E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07130 4f9715ac42aa7ad5e0f8003b1374a40b 233 Gene3D G3DSA:3.40.50.300 1 232 7.4E-60 T 29-03-2018 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 Gene3D G3DSA:1.20.1080.10 1 236 2.8E-83 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 Pfam PF00230 Major intrinsic protein 2 229 1.3E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 SUPERFAMILY SSF81338 2 234 1.09E-72 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 PRINTS PR00783 Major intrinsic protein family signature 212 232 1.6E-51 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 PRINTS PR00783 Major intrinsic protein family signature 135 153 1.6E-51 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 PRINTS PR00783 Major intrinsic protein family signature 80 99 1.6E-51 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 PRINTS PR00783 Major intrinsic protein family signature 165 187 1.6E-51 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 PRINTS PR00783 Major intrinsic protein family signature 1 19 1.6E-51 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 PRINTS PR00783 Major intrinsic protein family signature 43 67 1.6E-51 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 TIGRFAM TIGR00861 MIP: MIP family channel proteins 5 229 1.2E-61 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS04115 f18f015113a1cced7563d924fb888c08 236 ProSitePatterns PS00221 MIP family signature. 61 69 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS06060 981002475891c25c23dc7b11880261c5 294 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 67 8.7E-11 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SPSF3K_RS06060 981002475891c25c23dc7b11880261c5 294 SUPERFAMILY SSF53697 75 256 5.78E-25 T 29-03-2018 SPSF3K_RS06060 981002475891c25c23dc7b11880261c5 294 Gene3D G3DSA:3.40.50.10490 97 293 9.4E-20 T 29-03-2018 SPSF3K_RS06060 981002475891c25c23dc7b11880261c5 294 SUPERFAMILY SSF46689 11 71 3.4E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS06060 981002475891c25c23dc7b11880261c5 294 Gene3D G3DSA:1.10.10.10 2 96 2.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06060 981002475891c25c23dc7b11880261c5 294 Pfam PF01380 SIS domain 128 235 3.8E-14 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS07220 c9ef2eccf6206d0bbfcd523ddc8074a0 213 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 105 5.1E-29 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPSF3K_RS07220 c9ef2eccf6206d0bbfcd523ddc8074a0 213 Gene3D G3DSA:1.10.3720.10 2 213 2.2E-46 T 29-03-2018 SPSF3K_RS07220 c9ef2eccf6206d0bbfcd523ddc8074a0 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 210 1.4E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS07220 c9ef2eccf6206d0bbfcd523ddc8074a0 213 SUPERFAMILY SSF161098 10 198 3.14E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS08510 b1d8c4f4efe9a5f5975596c9cb832b92 98 Pfam PF06961 Protein of unknown function (DUF1294) 13 67 2.9E-25 T 29-03-2018 IPR010718 Protein of unknown function DUF1294 SPSF3K_RS04755 80faf43af1581d17300e3212c9560439 224 Pfam PF13309 HTH domain 161 219 2.7E-20 T 29-03-2018 SPSF3K_RS04755 80faf43af1581d17300e3212c9560439 224 Pfam PF08348 YheO-like PAS domain 6 119 2.1E-31 T 29-03-2018 IPR013559 YheO-like SPSF3K_RS04755 80faf43af1581d17300e3212c9560439 224 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 1 134 1.0E-52 T 29-03-2018 IPR013559 YheO-like SPSF3K_RS04755 80faf43af1581d17300e3212c9560439 224 Gene3D G3DSA:1.10.10.60 144 221 6.6E-7 T 29-03-2018 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 37 499 1.3E-149 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 Pfam PF02887 Pyruvate kinase, alpha/beta domain 386 496 3.9E-35 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 PRINTS PR01050 Pyruvate kinase family signature 81 97 2.1E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 PRINTS PR01050 Pyruvate kinase family signature 214 228 2.1E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 PRINTS PR01050 Pyruvate kinase family signature 297 321 2.1E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 PRINTS PR01050 Pyruvate kinase family signature 322 340 2.1E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 PRINTS PR01050 Pyruvate kinase family signature 245 271 2.1E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 PRINTS PR01050 Pyruvate kinase family signature 272 296 2.1E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 PRINTS PR01050 Pyruvate kinase family signature 341 357 2.1E-66 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 Gene3D G3DSA:3.20.20.60 1 139 7.2E-13 T 29-03-2018 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 Gene3D G3DSA:3.20.20.60 196 349 8.8E-60 T 29-03-2018 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 SUPERFAMILY SSF52935 351 499 7.33E-41 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 Gene3D G3DSA:3.40.1380.20 350 500 2.6E-51 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 SUPERFAMILY SSF51621 2 96 1.26E-84 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 SUPERFAMILY SSF51621 184 367 1.26E-84 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 Gene3D G3DSA:2.40.33.10 140 195 3.6E-14 T 29-03-2018 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 Pfam PF00224 Pyruvate kinase, barrel domain 3 370 4.3E-147 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 SPSF3K_RS07260 963a1ec1a5a50af8abbb1d876f59b030 500 SUPERFAMILY SSF50800 92 194 1.6E-17 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain SPSF3K_RS10900 eb5576704b04d80537a10990b90ece05 122 Pfam PF01381 Helix-turn-helix 8 62 1.7E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS10900 eb5576704b04d80537a10990b90ece05 122 Gene3D G3DSA:1.10.260.40 1 94 4.5E-20 T 29-03-2018 SPSF3K_RS10900 eb5576704b04d80537a10990b90ece05 122 SMART SM00530 7 62 5.6E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS10900 eb5576704b04d80537a10990b90ece05 122 SUPERFAMILY SSF47413 2 68 6.4E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS09205 bf5c970eb9f3e2096351e00dc91bea7b 152 SUPERFAMILY SSF46785 5 136 2.33E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09205 bf5c970eb9f3e2096351e00dc91bea7b 152 SMART SM00347 23 125 6.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS09205 bf5c970eb9f3e2096351e00dc91bea7b 152 Pfam PF01047 MarR family 30 89 4.3E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS09205 bf5c970eb9f3e2096351e00dc91bea7b 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.0E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS09205 bf5c970eb9f3e2096351e00dc91bea7b 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 1.0E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS09205 bf5c970eb9f3e2096351e00dc91bea7b 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 1.0E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS09205 bf5c970eb9f3e2096351e00dc91bea7b 152 Gene3D G3DSA:1.10.10.10 1 139 9.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09205 bf5c970eb9f3e2096351e00dc91bea7b 152 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SPSF3K_RS07845 823de844d2b38e80432cba0e159765e6 392 SUPERFAMILY SSF53474 132 385 4.56E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS07845 823de844d2b38e80432cba0e159765e6 392 Gene3D G3DSA:3.40.50.1820 122 392 2.3E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS07845 823de844d2b38e80432cba0e159765e6 392 Pfam PF07859 alpha/beta hydrolase fold 150 344 3.2E-20 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SPSF3K_RS00230 8a1895b5eeff04e02597fe6f4dada79e 405 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 239 1.9E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SPSF3K_RS00230 8a1895b5eeff04e02597fe6f4dada79e 405 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 257 397 2.4E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SPSF3K_RS00230 8a1895b5eeff04e02597fe6f4dada79e 405 SUPERFAMILY SSF47203 253 402 2.09E-37 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 SPSF3K_RS00230 8a1895b5eeff04e02597fe6f4dada79e 405 SUPERFAMILY SSF56645 18 249 5.1E-39 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SPSF3K_RS00230 8a1895b5eeff04e02597fe6f4dada79e 405 Gene3D G3DSA:2.40.110.10 147 240 7.8E-24 T 29-03-2018 SPSF3K_RS00230 8a1895b5eeff04e02597fe6f4dada79e 405 Gene3D G3DSA:1.20.140.10 241 403 1.2E-35 T 29-03-2018 SPSF3K_RS00230 8a1895b5eeff04e02597fe6f4dada79e 405 Gene3D G3DSA:1.10.540.10 23 146 5.2E-5 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SPSF3K_RS06770 e4ecefb8d328419a64228f82e40b6115 332 Pfam PF05598 Transposase domain (DUF772) 51 120 8.9E-21 T 29-03-2018 IPR008490 Transposase InsH, N-terminal SPSF3K_RS06770 e4ecefb8d328419a64228f82e40b6115 332 Pfam PF01609 Transposase DDE domain 135 317 2.4E-35 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 SUPERFAMILY SSF81296 13 110 4.9E-15 T 29-03-2018 IPR014756 Immunoglobulin E-set SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 SUPERFAMILY SSF51445 79 511 4.17E-97 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 1 621 37.159 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 Gene3D G3DSA:3.20.20.80 143 530 1.3E-66 T 29-03-2018 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 SUPERFAMILY SSF51011 519 621 9.78E-26 T 29-03-2018 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 22 103 2.7E-17 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 SMART SM00642 147 498 4.7E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 PIRSF PIRSF000463 1 627 6.5E-243 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 Gene3D G3DSA:2.60.40.1180 531 627 4.9E-22 T 29-03-2018 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 Gene3D G3DSA:2.60.40.10 17 142 7.5E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 Pfam PF00128 Alpha amylase, catalytic domain 172 246 1.1E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 524 621 8.2E-17 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 SPSF3K_RS04850 82a1b1d645499e71e0c9e95921925d71 627 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 6 617 1.5E-200 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 Gene3D G3DSA:1.10.287.130 222 279 3.2E-16 T 29-03-2018 SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 SMART SM00388 216 283 4.7E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 SUPERFAMILY SSF55874 274 436 7.73E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 SUPERFAMILY SSF47384 204 282 4.12E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 4.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 4.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 435 4.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 391 4.4E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 SMART SM00387 326 438 3.6E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 436 9.3E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 Gene3D G3DSA:3.30.450.20 102 221 7.3E-8 T 29-03-2018 SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 Gene3D G3DSA:3.30.565.10 285 445 2.1E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04215 75b5cd1b483a142c37a2e3ade398cbd6 445 Pfam PF00512 His Kinase A (phospho-acceptor) domain 219 280 1.5E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPSF3K_RS05870 2e4e8e5fd0ba1b2cf7d58877141167a0 56 SUPERFAMILY SSF47598 24 42 1.38E-7 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SPSF3K_RS05870 2e4e8e5fd0ba1b2cf7d58877141167a0 56 Gene3D G3DSA:1.10.1220.10 29 42 0.0014 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SPSF3K_RS05870 2e4e8e5fd0ba1b2cf7d58877141167a0 56 Pfam PF07764 Omega Transcriptional Repressor 2 42 2.6E-28 T 29-03-2018 IPR011686 Omega transcriptional repressor SPSF3K_RS01935 5c01543a3198420fdf133cd17878301f 313 Gene3D G3DSA:3.30.450.90 1 109 9.7E-22 T 29-03-2018 SPSF3K_RS01935 5c01543a3198420fdf133cd17878301f 313 Pfam PF00437 Type II/IV secretion system protein 8 267 3.1E-48 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SPSF3K_RS01935 5c01543a3198420fdf133cd17878301f 313 Gene3D G3DSA:3.40.50.300 123 307 2.7E-24 T 29-03-2018 SPSF3K_RS01935 5c01543a3198420fdf133cd17878301f 313 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 197 211 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SPSF3K_RS01935 5c01543a3198420fdf133cd17878301f 313 SUPERFAMILY SSF52540 5 268 1.57E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03710 31fb7c165b23e93df777cd63a3f65529 221 Gene3D G3DSA:1.25.40.290 127 221 2.8E-22 T 29-03-2018 SPSF3K_RS03710 31fb7c165b23e93df777cd63a3f65529 221 SUPERFAMILY SSF48371 15 221 9.4E-48 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 SPSF3K_RS03710 31fb7c165b23e93df777cd63a3f65529 221 Gene3D G3DSA:1.20.1660.10 9 126 4.8E-23 T 29-03-2018 SPSF3K_RS03710 31fb7c165b23e93df777cd63a3f65529 221 Pfam PF08713 DNA alkylation repair enzyme 14 221 6.6E-61 T 29-03-2018 IPR014825 DNA alkylation repair enzyme SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 SUPERFAMILY SSF55307 205 319 1.42E-41 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 174 1.2E-39 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 Gene3D G3DSA:3.40.50.1440 7 215 1.7E-39 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 Gene3D G3DSA:3.30.1330.20 216 325 3.9E-42 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 397 37.672 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 Pfam PF12327 FtsZ family, C-terminal domain 223 316 5.8E-29 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 SMART SM00864 14 206 3.4E-109 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 SMART SM00865 208 325 7.4E-48 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 SUPERFAMILY SSF52490 14 209 6.28E-67 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 PRINTS PR00423 Cell division protein FtsZ signature 190 212 1.9E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 PRINTS PR00423 Cell division protein FtsZ signature 127 148 1.9E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 PRINTS PR00423 Cell division protein FtsZ signature 213 234 1.9E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 PRINTS PR00423 Cell division protein FtsZ signature 99 119 1.9E-51 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 SPSF3K_RS08915 a64f316fd7014ef85bb1d5339aa04f9d 447 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 329 3.2E-125 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 SPSF3K_RS07975 6b33fe8a634d697656c6018e04a539dc 281 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 128 245 1.0E-41 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal SPSF3K_RS07975 6b33fe8a634d697656c6018e04a539dc 281 SUPERFAMILY SSF143597 51 249 3.01E-64 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal SPSF3K_RS07975 6b33fe8a634d697656c6018e04a539dc 281 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 25 260 2.7E-79 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 SPSF3K_RS07975 6b33fe8a634d697656c6018e04a539dc 281 PIRSF PIRSF004793 12 276 1.6E-83 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 SPSF3K_RS07975 6b33fe8a634d697656c6018e04a539dc 281 Gene3D G3DSA:3.40.1700.10 122 248 4.7E-36 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal SPSF3K_RS07975 6b33fe8a634d697656c6018e04a539dc 281 Hamap MF_01499 Diadenylate cyclase [dacA]. 10 264 30.2 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 SPSF3K_RS07775 c0081e3dc47fb86cf6be890968c1c83a 403 TIGRFAM TIGR01696 deoB: phosphopentomutase 6 396 4.1E-156 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 SPSF3K_RS07775 c0081e3dc47fb86cf6be890968c1c83a 403 Pfam PF01676 Metalloenzyme superfamily 6 390 5.8E-41 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 SPSF3K_RS07775 c0081e3dc47fb86cf6be890968c1c83a 403 Hamap MF_00740 Phosphopentomutase [deoB]. 4 399 53.489 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 SPSF3K_RS07775 c0081e3dc47fb86cf6be890968c1c83a 403 Gene3D G3DSA:3.30.70.1250 107 215 3.7E-49 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 SPSF3K_RS07775 c0081e3dc47fb86cf6be890968c1c83a 403 SUPERFAMILY SSF143856 108 226 1.57E-47 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 SPSF3K_RS07775 c0081e3dc47fb86cf6be890968c1c83a 403 SUPERFAMILY SSF53649 3 108 1.1E-78 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SPSF3K_RS07775 c0081e3dc47fb86cf6be890968c1c83a 403 SUPERFAMILY SSF53649 227 402 1.1E-78 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SPSF3K_RS07775 c0081e3dc47fb86cf6be890968c1c83a 403 Gene3D G3DSA:3.40.720.10 216 403 1.6E-18 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SPSF3K_RS07775 c0081e3dc47fb86cf6be890968c1c83a 403 PIRSF PIRSF001491 3 403 2.8E-151 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 SPSF3K_RS09655 15cff2e4066583fb2d43a8d09f0d411c 311 Gene3D G3DSA:3.10.25.10 207 311 1.2E-30 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPSF3K_RS09655 15cff2e4066583fb2d43a8d09f0d411c 311 SUPERFAMILY SSF50486 205 302 4.71E-31 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SPSF3K_RS09655 15cff2e4066583fb2d43a8d09f0d411c 311 Pfam PF02911 Formyl transferase, C-terminal domain 204 299 1.6E-28 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPSF3K_RS09655 15cff2e4066583fb2d43a8d09f0d411c 311 Gene3D G3DSA:3.40.50.170 1 206 1.8E-59 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPSF3K_RS09655 15cff2e4066583fb2d43a8d09f0d411c 311 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPSF3K_RS09655 15cff2e4066583fb2d43a8d09f0d411c 311 Pfam PF00551 Formyl transferase 3 179 3.1E-35 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPSF3K_RS09655 15cff2e4066583fb2d43a8d09f0d411c 311 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 302 1.2E-95 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SPSF3K_RS09655 15cff2e4066583fb2d43a8d09f0d411c 311 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 302 33.102 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 SPSF3K_RS09655 15cff2e4066583fb2d43a8d09f0d411c 311 SUPERFAMILY SSF53328 3 203 2.35E-58 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPSF3K_RS06970 e513b17a330a93a4a9c78677ca2fd2fd 229 SUPERFAMILY SSF102645 1 226 2.22E-48 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SPSF3K_RS06970 e513b17a330a93a4a9c78677ca2fd2fd 229 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 2 191 6.3E-32 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SPSF3K_RS06970 e513b17a330a93a4a9c78677ca2fd2fd 229 Gene3D G3DSA:3.40.50.10300 1 227 6.7E-55 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 SPSF3K_RS06970 e513b17a330a93a4a9c78677ca2fd2fd 229 TIGRFAM TIGR02114 coaB_strep: phosphopantothenate--cysteine ligase 1 228 2.1E-95 T 29-03-2018 IPR011848 Phosphopantothenate--cysteine ligase SPSF3K_RS02590 3e95bd3c331fa2ac6c1cdb1525fef7bb 204 SUPERFAMILY SSF55469 1 203 2.28E-61 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SPSF3K_RS02590 3e95bd3c331fa2ac6c1cdb1525fef7bb 204 Pfam PF00881 Nitroreductase family 8 182 1.9E-11 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SPSF3K_RS02590 3e95bd3c331fa2ac6c1cdb1525fef7bb 204 Gene3D G3DSA:3.40.109.10 1 203 1.4E-24 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SPSF3K_RS07105 66ff3a96597161b7d7846bb6ed97fb7c 293 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 222 3.7E-9 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 SPSF3K_RS07105 66ff3a96597161b7d7846bb6ed97fb7c 293 SUPERFAMILY SSF55120 1 228 1.27E-77 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS07105 66ff3a96597161b7d7846bb6ed97fb7c 293 Gene3D G3DSA:3.30.2350.10 1 226 1.1E-79 T 29-03-2018 SPSF3K_RS07105 66ff3a96597161b7d7846bb6ed97fb7c 293 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 292 18.727 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS07105 66ff3a96597161b7d7846bb6ed97fb7c 293 Gene3D G3DSA:2.30.130.10 237 292 3.1E-11 T 29-03-2018 IPR002478 PUA domain GO:0003723 SPSF3K_RS07105 66ff3a96597161b7d7846bb6ed97fb7c 293 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 216 1.4E-75 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS07105 66ff3a96597161b7d7846bb6ed97fb7c 293 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 178 1.3E-55 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 471 33.845 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 2.1E-75 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 Gene3D G3DSA:1.10.260.30 328 432 1.5E-34 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.9E-21 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 Gene3D G3DSA:3.40.50.300 101 298 3.2E-38 T 29-03-2018 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 9.0E-187 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 Gene3D G3DSA:1.20.120.140 1 92 7.6E-29 T 29-03-2018 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 SMART SM00382 100 248 5.9E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 SMART SM00962 101 297 8.0E-110 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 SUPERFAMILY SSF52540 43 355 3.54E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 SMART SM00963 2 87 8.0E-31 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 Pfam PF02978 Signal peptide binding domain 328 427 9.1E-31 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SPSF3K_RS06605 18d9939ca07473fb88c4a5ce96731445 524 SUPERFAMILY SSF47446 328 430 3.6E-35 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 SPSF3K_RS02090 5253d21b7d503f057aa469af6cccff48 118 Gene3D G3DSA:1.10.8.290 2 115 2.6E-44 T 29-03-2018 IPR023204 SP1917 domain SPSF3K_RS02090 5253d21b7d503f057aa469af6cccff48 118 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 4 112 7.6E-41 T 29-03-2018 IPR014580 Uncharacterised conserved protein UCP033199 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 SUPERFAMILY SSF52777 234 469 6.23E-75 T 29-03-2018 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 SUPERFAMILY SSF47005 171 213 2.22E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 Gene3D G3DSA:4.10.320.10 174 220 8.7E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 Gene3D G3DSA:4.10.320.10 127 173 2.0E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 SUPERFAMILY SSF51230 1 90 1.44E-25 T 29-03-2018 IPR011053 Single hybrid motif SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 Pfam PF00364 Biotin-requiring enzyme 4 76 4.0E-19 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 SUPERFAMILY SSF47005 126 170 3.66E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 239 469 2.3E-74 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 Gene3D G3DSA:3.30.559.10 221 470 1.5E-77 T 29-03-2018 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 Gene3D G3DSA:2.40.50.100 5 77 3.5E-14 T 29-03-2018 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 Pfam PF02817 e3 binding domain 174 209 2.3E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SPSF3K_RS08000 832e4c2d7d9436fc5d854e3391cff9d0 470 Pfam PF02817 e3 binding domain 132 167 1.5E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SPSF3K_RS01045 635d8c0e8c38e2e3b31e643748196e72 346 SMART SM00382 89 259 2.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS01045 635d8c0e8c38e2e3b31e643748196e72 346 ProSitePatterns PS00211 ABC transporters family signature. 183 197 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS01045 635d8c0e8c38e2e3b31e643748196e72 346 Gene3D G3DSA:3.40.50.300 61 322 1.4E-59 T 29-03-2018 SPSF3K_RS01045 635d8c0e8c38e2e3b31e643748196e72 346 Pfam PF00005 ABC transporter 80 210 3.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS01045 635d8c0e8c38e2e3b31e643748196e72 346 SUPERFAMILY SSF52540 63 274 1.78E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02960 cc797c45abc7cc1b5dcba0a55aa4e953 62 Gene3D G3DSA:2.30.170.40 2 62 1.2E-20 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS02960 cc797c45abc7cc1b5dcba0a55aa4e953 62 Pfam PF00830 Ribosomal L28 family 3 58 4.9E-22 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS02960 cc797c45abc7cc1b5dcba0a55aa4e953 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.604 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS02960 cc797c45abc7cc1b5dcba0a55aa4e953 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 1.8E-22 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS02960 cc797c45abc7cc1b5dcba0a55aa4e953 62 SUPERFAMILY SSF143800 1 60 8.24E-25 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00060 af7609782b0cde670e5c9b451d394a6f 364 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00060 af7609782b0cde670e5c9b451d394a6f 364 Gene3D G3DSA:3.40.50.300 1 362 1.5E-29 T 29-03-2018 SPSF3K_RS00060 af7609782b0cde670e5c9b451d394a6f 364 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 364 99.836 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00060 af7609782b0cde670e5c9b451d394a6f 364 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 360 9.5E-132 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00060 af7609782b0cde670e5c9b451d394a6f 364 SUPERFAMILY SSF52540 1 355 4.46E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00060 af7609782b0cde670e5c9b451d394a6f 364 ProSitePatterns PS00618 RecF protein signature 2. 305 323 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00060 af7609782b0cde670e5c9b451d394a6f 364 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 360 2.7E-14 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal SPSF3K_RS02330 a0b77ab20b5bd86cf645dbbf1a3663eb 186 Pfam PF03641 Possible lysine decarboxylase 45 170 1.8E-35 T 29-03-2018 IPR031100 LOG family SPSF3K_RS02330 a0b77ab20b5bd86cf645dbbf1a3663eb 186 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 176 5.5E-48 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG SPSF3K_RS02330 a0b77ab20b5bd86cf645dbbf1a3663eb 186 SUPERFAMILY SSF102405 2 178 3.51E-57 T 29-03-2018 SPSF3K_RS02330 a0b77ab20b5bd86cf645dbbf1a3663eb 186 Gene3D G3DSA:3.40.50.450 1 185 1.4E-49 T 29-03-2018 SPSF3K_RS09050 4ef5d9254e419db6974a508c1af7ff5b 330 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 1 330 45.993 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 SPSF3K_RS09050 4ef5d9254e419db6974a508c1af7ff5b 330 PIRSF PIRSF001555 1 330 1.9E-154 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 SPSF3K_RS09050 4ef5d9254e419db6974a508c1af7ff5b 330 Gene3D G3DSA:3.30.930.10 1 328 6.6E-34 T 29-03-2018 SPSF3K_RS09050 4ef5d9254e419db6974a508c1af7ff5b 330 SUPERFAMILY SSF55681 5 330 4.02E-94 T 29-03-2018 SPSF3K_RS09050 4ef5d9254e419db6974a508c1af7ff5b 330 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 1 330 7.4E-183 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 SPSF3K_RS09050 4ef5d9254e419db6974a508c1af7ff5b 330 Pfam PF03590 Aspartate-ammonia ligase 9 244 7.6E-95 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 SPSF3K_RS02000 10ebd84ac9b1401f9edb9c1e616a8a20 355 TIGRFAM TIGR03107 glu_aminopep: glutamyl aminopeptidase 5 353 5.4E-198 T 29-03-2018 IPR017538 Peptidase M42, glutamyl aminopeptidase MetaCyc: PWY-5706|MetaCyc: PWY-5707|MetaCyc: PWY-7614 SPSF3K_RS02000 10ebd84ac9b1401f9edb9c1e616a8a20 355 Pfam PF05343 M42 glutamyl aminopeptidase 45 334 2.1E-95 T 29-03-2018 IPR008007 Peptidase M42 SPSF3K_RS02000 10ebd84ac9b1401f9edb9c1e616a8a20 355 Gene3D G3DSA:2.40.30.40 70 162 4.5E-20 T 29-03-2018 IPR023367 Peptidase M42, domain 2 SPSF3K_RS02000 10ebd84ac9b1401f9edb9c1e616a8a20 355 SUPERFAMILY SSF53187 4 81 3.03E-58 T 29-03-2018 SPSF3K_RS02000 10ebd84ac9b1401f9edb9c1e616a8a20 355 SUPERFAMILY SSF53187 174 352 3.03E-58 T 29-03-2018 SPSF3K_RS02000 10ebd84ac9b1401f9edb9c1e616a8a20 355 SUPERFAMILY SSF101821 71 182 3.97E-25 T 29-03-2018 SPSF3K_RS02000 10ebd84ac9b1401f9edb9c1e616a8a20 355 Gene3D G3DSA:3.40.630.10 163 354 1.3E-31 T 29-03-2018 SPSF3K_RS02000 10ebd84ac9b1401f9edb9c1e616a8a20 355 PIRSF PIRSF001123 1 355 1.4E-133 T 29-03-2018 IPR008007 Peptidase M42 SPSF3K_RS06230 c50e8c863755183bf9f38139c70e6046 226 TIGRFAM TIGR00608 radc: DNA repair protein RadC 12 224 2.6E-69 T 29-03-2018 IPR001405 RadC protein SPSF3K_RS06230 c50e8c863755183bf9f38139c70e6046 226 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site SPSF3K_RS06230 c50e8c863755183bf9f38139c70e6046 226 Pfam PF04002 RadC-like JAB domain 106 222 2.0E-39 T 29-03-2018 IPR025657 RadC-like JAB domain SPSF3K_RS06230 c50e8c863755183bf9f38139c70e6046 226 Gene3D G3DSA:3.40.140.10 100 225 2.0E-41 T 29-03-2018 SPSF3K_RS10545 fe104d22a5050f1eaccaf1123476ba7d 592 Gene3D G3DSA:3.40.50.1110 394 586 3.1E-7 T 29-03-2018 SPSF3K_RS10545 fe104d22a5050f1eaccaf1123476ba7d 592 Pfam PF01757 Acyltransferase family 4 344 5.6E-22 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SPSF3K_RS07670 b56f789185449877df36e47006bd399b 354 PRINTS PR01713 Nucleotide sugar epimerase signature 37 53 4.2E-27 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 SPSF3K_RS07670 b56f789185449877df36e47006bd399b 354 PRINTS PR01713 Nucleotide sugar epimerase signature 229 244 4.2E-27 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 SPSF3K_RS07670 b56f789185449877df36e47006bd399b 354 PRINTS PR01713 Nucleotide sugar epimerase signature 312 329 4.2E-27 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 SPSF3K_RS07670 b56f789185449877df36e47006bd399b 354 PRINTS PR01713 Nucleotide sugar epimerase signature 263 278 4.2E-27 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 SPSF3K_RS07670 b56f789185449877df36e47006bd399b 354 Gene3D G3DSA:3.40.50.720 7 202 4.5E-36 T 29-03-2018 SPSF3K_RS07670 b56f789185449877df36e47006bd399b 354 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 253 2.4E-53 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SPSF3K_RS07670 b56f789185449877df36e47006bd399b 354 Gene3D G3DSA:3.90.25.10 203 353 2.3E-30 T 29-03-2018 SPSF3K_RS07670 b56f789185449877df36e47006bd399b 354 SUPERFAMILY SSF51735 1 350 9.86E-85 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS08950 43347a869c1e09f6669bf9e0a14c507b 129 SUPERFAMILY SSF52821 10 121 9.95E-22 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS08950 43347a869c1e09f6669bf9e0a14c507b 129 Gene3D G3DSA:3.40.250.10 22 128 1.3E-17 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS08950 43347a869c1e09f6669bf9e0a14c507b 129 Pfam PF00581 Rhodanese-like domain 36 122 1.3E-12 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS08950 43347a869c1e09f6669bf9e0a14c507b 129 SMART SM00450 31 127 8.5E-5 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS00980 583577670b4ca8a6cfaa92dd6bd86671 231 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 228 7.9E-37 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SPSF3K_RS00980 583577670b4ca8a6cfaa92dd6bd86671 231 SUPERFAMILY SSF51219 1 226 5.75E-66 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SPSF3K_RS00980 583577670b4ca8a6cfaa92dd6bd86671 231 Pfam PF01987 Mitochondrial biogenesis AIM24 3 212 3.3E-50 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SPSF3K_RS00980 583577670b4ca8a6cfaa92dd6bd86671 231 Gene3D G3DSA:3.60.160.10 1 231 1.5E-58 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 SPSF3K_RS02915 2d4f9e6aa67a9a558001d26e4c16d26d 187 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 83 3.4E-9 T 29-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 SPSF3K_RS02915 2d4f9e6aa67a9a558001d26e4c16d26d 187 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 185 15.404 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 SPSF3K_RS02915 2d4f9e6aa67a9a558001d26e4c16d26d 187 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 13 94 6.7E-30 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 SUPERFAMILY SSF50151 2 53 3.92E-16 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 SUPERFAMILY SSF63520 174 274 8.89E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 SMART SM01061 1 59 4.0E-23 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 SUPERFAMILY SSF63520 59 165 1.18E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 Pfam PF00874 PRD domain 182 273 9.1E-18 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 Pfam PF00874 PRD domain 77 163 2.7E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 Gene3D G3DSA:1.10.1790.10 168 276 2.5E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 Gene3D G3DSA:1.10.1790.10 46 167 1.1E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 Pfam PF03123 CAT RNA binding domain 2 54 4.8E-20 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 SPSF3K_RS06165 f11f115b40fcd930a83a34d990c7dc8b 280 Gene3D G3DSA:2.30.24.10 2 45 4.3E-21 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 SMART SM00904 181 305 6.4E-55 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 PIRSF PIRSF004491 1 310 9.8E-97 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 Gene3D G3DSA:2.40.30.30 177 310 1.8E-37 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 SUPERFAMILY SSF82114 172 305 8.72E-45 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 Gene3D G3DSA:3.40.50.620 1 176 2.6E-41 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 SUPERFAMILY SSF52374 17 174 1.52E-26 T 29-03-2018 SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 303 1.8E-75 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 58 4.0E-7 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 Pfam PF01687 Riboflavin kinase 182 301 1.6E-31 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 SPSF3K_RS07100 d66a7973f1bd4b873012ad918f16e184 310 Pfam PF06574 FAD synthetase 13 164 5.9E-45 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 SPSF3K_RS03595 13c8c5d43a15c3189652399d443aba48 147 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 11 116 5.2E-11 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA SPSF3K_RS03595 13c8c5d43a15c3189652399d443aba48 147 Gene3D G3DSA:1.20.1500.10 10 119 5.1E-16 T 29-03-2018 IPR023378 YheA/YmcA-like domain SPSF3K_RS03595 13c8c5d43a15c3189652399d443aba48 147 SUPERFAMILY SSF158622 6 126 1.24E-16 T 29-03-2018 IPR023378 YheA/YmcA-like domain SPSF3K_RS06645 6da250cec158d9b6a4495698b2678e89 278 SUPERFAMILY SSF56784 4 277 5.93E-67 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS06645 6da250cec158d9b6a4495698b2678e89 278 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 29-03-2018 SPSF3K_RS06645 6da250cec158d9b6a4495698b2678e89 278 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 274 2.7E-61 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS06645 6da250cec158d9b6a4495698b2678e89 278 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 247 6.9E-21 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS06645 6da250cec158d9b6a4495698b2678e89 278 Gene3D G3DSA:3.40.50.1000 2 278 7.0E-37 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS06645 6da250cec158d9b6a4495698b2678e89 278 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 274 4.1E-63 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS01135 c18c1a06fbe581a27c3d5fbe57f9c6a7 278 Gene3D G3DSA:3.40.50.150 13 260 3.4E-31 T 29-03-2018 SPSF3K_RS01135 c18c1a06fbe581a27c3d5fbe57f9c6a7 278 PIRSF PIRSF018249 1 278 2.0E-85 T 29-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 SPSF3K_RS01135 c18c1a06fbe581a27c3d5fbe57f9c6a7 278 Pfam PF13649 Methyltransferase domain 96 169 1.8E-10 T 29-03-2018 SPSF3K_RS01135 c18c1a06fbe581a27c3d5fbe57f9c6a7 278 SUPERFAMILY SSF53335 17 207 1.63E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 Gene3D G3DSA:3.50.50.60 2 136 3.3E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 429 4.8E-13 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 SUPERFAMILY SSF51905 2 197 1.86E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 1.9E-15 T 29-03-2018 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.9E-15 T 29-03-2018 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.9E-15 T 29-03-2018 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 1.9E-15 T 29-03-2018 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 306 6.7E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 Gene3D G3DSA:3.30.390.30 326 453 6.0E-28 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 6.1E-21 T 29-03-2018 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 6.1E-21 T 29-03-2018 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 6.1E-21 T 29-03-2018 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.1E-21 T 29-03-2018 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 6.1E-21 T 29-03-2018 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 Pfam PF00581 Rhodanese-like domain 457 542 3.8E-8 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 Gene3D G3DSA:3.50.50.60 145 325 1.3E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 SUPERFAMILY SSF51905 153 316 9.07E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 Gene3D G3DSA:3.40.250.10 454 550 7.1E-18 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 SUPERFAMILY SSF52821 434 541 1.65E-22 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 SUPERFAMILY SSF55424 322 445 2.58E-32 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS01790 c25272b5810da2b0e340cf59b0586465 551 SMART SM00450 453 546 4.2E-14 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS03020 935e823219a9003a1546f94addd76e82 256 Pfam PF00005 ABC transporter 19 171 7.5E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS03020 935e823219a9003a1546f94addd76e82 256 Gene3D G3DSA:3.40.50.300 1 248 3.6E-45 T 29-03-2018 SPSF3K_RS03020 935e823219a9003a1546f94addd76e82 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 243 1.6E-110 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 SPSF3K_RS03020 935e823219a9003a1546f94addd76e82 256 SUPERFAMILY SSF52540 4 230 8.12E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03020 935e823219a9003a1546f94addd76e82 256 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS03020 935e823219a9003a1546f94addd76e82 256 SMART SM00382 28 230 4.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS04360 3ce7fc0fb8f4aaad95c129ae9457e945 513 Gene3D G3DSA:1.20.200.10 200 512 5.8E-120 T 29-03-2018 SPSF3K_RS04360 3ce7fc0fb8f4aaad95c129ae9457e945 513 Pfam PF00221 Aromatic amino acid lyase 12 470 7.7E-198 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 SPSF3K_RS04360 3ce7fc0fb8f4aaad95c129ae9457e945 513 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 140 156 - T 29-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 SPSF3K_RS04360 3ce7fc0fb8f4aaad95c129ae9457e945 513 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 6 508 1.5E-198 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04360 3ce7fc0fb8f4aaad95c129ae9457e945 513 Gene3D G3DSA:1.10.275.10 3 198 2.3E-78 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SPSF3K_RS04360 3ce7fc0fb8f4aaad95c129ae9457e945 513 SUPERFAMILY SSF48557 2 500 2.59E-192 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SPSF3K_RS04360 3ce7fc0fb8f4aaad95c129ae9457e945 513 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 4 505 46.17 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS01715 63e871ec4193cb4e85b63bcb4e778d64 316 Gene3D G3DSA:2.60.120.10 1 222 4.9E-55 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS01715 63e871ec4193cb4e85b63bcb4e778d64 316 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 102 312 2.5E-42 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SPSF3K_RS01715 63e871ec4193cb4e85b63bcb4e778d64 316 SUPERFAMILY SSF51182 1 312 3.16E-101 T 29-03-2018 IPR011051 RmlC-like cupin domain SPSF3K_RS01715 63e871ec4193cb4e85b63bcb4e778d64 316 PIRSF PIRSF036894 2 314 2.1E-126 T 29-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 SPSF3K_RS01715 63e871ec4193cb4e85b63bcb4e778d64 316 Pfam PF01238 Phosphomannose isomerase type I 7 312 2.2E-53 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 SPSF3K_RS01715 63e871ec4193cb4e85b63bcb4e778d64 316 Gene3D G3DSA:2.60.120.10 235 314 9.1E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS09440 fa032f4f9e0395cd77080a1f8f9a8620 76 Gene3D G3DSA:3.30.70.100 1 73 4.1E-15 T 29-03-2018 SPSF3K_RS09440 fa032f4f9e0395cd77080a1f8f9a8620 76 SUPERFAMILY SSF55008 1 72 1.19E-14 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS09440 fa032f4f9e0395cd77080a1f8f9a8620 76 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SPSF3K_RS09440 fa032f4f9e0395cd77080a1f8f9a8620 76 Pfam PF00403 Heavy-metal-associated domain 7 69 4.5E-13 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS10100 937e858d2a48f49ff4536a816343abc3 322 Gene3D G3DSA:3.20.20.70 1 314 6.4E-62 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS10100 937e858d2a48f49ff4536a816343abc3 322 TIGRFAM TIGR03151 enACPred_II: putative enoyl-[acyl-carrier-protein] reductase II 2 311 3.2E-152 T 29-03-2018 IPR017569 Enoyl-(acyl-carrier-protein) reductase II, putative SPSF3K_RS10100 937e858d2a48f49ff4536a816343abc3 322 Pfam PF03060 Nitronate monooxygenase 3 301 3.0E-71 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SPSF3K_RS10100 937e858d2a48f49ff4536a816343abc3 322 SUPERFAMILY SSF51412 1 309 1.98E-73 T 29-03-2018 SPSF3K_RS02450 cf54840e82ed465469ba88e8cd0bf950 331 SMART SM00354 1 71 1.2E-26 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02450 cf54840e82ed465469ba88e8cd0bf950 331 Gene3D G3DSA:1.10.260.40 2 54 5.1E-21 T 29-03-2018 SPSF3K_RS02450 cf54840e82ed465469ba88e8cd0bf950 331 SUPERFAMILY SSF47413 2 59 8.44E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS02450 cf54840e82ed465469ba88e8cd0bf950 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 SPSF3K_RS02450 cf54840e82ed465469ba88e8cd0bf950 331 Gene3D G3DSA:3.40.50.2300 55 184 5.0E-19 T 29-03-2018 SPSF3K_RS02450 cf54840e82ed465469ba88e8cd0bf950 331 Gene3D G3DSA:3.40.50.2300 185 314 1.8E-18 T 29-03-2018 SPSF3K_RS02450 cf54840e82ed465469ba88e8cd0bf950 331 Pfam PF13377 Periplasmic binding protein-like domain 180 328 1.9E-16 T 29-03-2018 SPSF3K_RS02450 cf54840e82ed465469ba88e8cd0bf950 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.5E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02450 cf54840e82ed465469ba88e8cd0bf950 331 SUPERFAMILY SSF53822 58 313 1.33E-38 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS00065 3dd69879dfcd2aed5f828eec93e4d2d3 134 Gene3D G3DSA:3.10.290.10 10 117 2.8E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS00065 3dd69879dfcd2aed5f828eec93e4d2d3 134 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 2 61 1.3E-26 T 29-03-2018 IPR014330 RNA-binding S4-related,YaaA SPSF3K_RS00065 3dd69879dfcd2aed5f828eec93e4d2d3 134 Pfam PF13275 S4 domain 4 66 1.2E-22 T 29-03-2018 SPSF3K_RS00065 3dd69879dfcd2aed5f828eec93e4d2d3 134 SUPERFAMILY SSF55174 2 65 9.16E-16 T 29-03-2018 SPSF3K_RS01745 4b16a22f2a9aa42f6c00a8d211545df2 305 PRINTS PR00069 Aldo-keto reductase signature 38 62 9.7E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS01745 4b16a22f2a9aa42f6c00a8d211545df2 305 PRINTS PR00069 Aldo-keto reductase signature 101 119 9.7E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS01745 4b16a22f2a9aa42f6c00a8d211545df2 305 PRINTS PR00069 Aldo-keto reductase signature 185 214 9.7E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS01745 4b16a22f2a9aa42f6c00a8d211545df2 305 PRINTS PR00069 Aldo-keto reductase signature 233 257 9.7E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS01745 4b16a22f2a9aa42f6c00a8d211545df2 305 Pfam PF00248 Aldo/keto reductase family 16 296 3.2E-49 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS01745 4b16a22f2a9aa42f6c00a8d211545df2 305 Gene3D G3DSA:3.20.20.100 1 303 5.7E-70 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS01745 4b16a22f2a9aa42f6c00a8d211545df2 305 SUPERFAMILY SSF51430 1 298 1.31E-71 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS06995 ef2530f6c8da4884a166e76c780b51a1 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 333 2.4E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPSF3K_RS06995 ef2530f6c8da4884a166e76c780b51a1 355 Gene3D G3DSA:1.10.3470.10 53 350 3.1E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS03670 0279fb766b05a145a06e7dc17690464d 363 SUPERFAMILY SSF53383 2 360 2.81E-102 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS03670 0279fb766b05a145a06e7dc17690464d 363 Gene3D G3DSA:3.40.640.10 15 259 6.8E-27 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS03670 0279fb766b05a145a06e7dc17690464d 363 Gene3D G3DSA:3.90.1150.10 260 361 1.5E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS03670 0279fb766b05a145a06e7dc17690464d 363 Pfam PF00266 Aminotransferase class-V 3 350 2.9E-45 T 29-03-2018 IPR000192 Aminotransferase class V domain SPSF3K_RS03670 0279fb766b05a145a06e7dc17690464d 363 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 1 362 49.175 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SPSF3K_RS03670 0279fb766b05a145a06e7dc17690464d 363 PIRSF PIRSF000525 1 363 3.0E-145 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SPSF3K_RS03670 0279fb766b05a145a06e7dc17690464d 363 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 3 361 1.6E-148 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 SPSF3K_RS03670 0279fb766b05a145a06e7dc17690464d 363 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 190 209 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SPSF3K_RS08540 a65391e4718b1a5ded0f361653c4172f 87 SUPERFAMILY SSF55594 1 83 4.06E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SPSF3K_RS08540 a65391e4718b1a5ded0f361653c4172f 87 Pfam PF00381 PTS HPr component phosphorylation site 3 81 3.3E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SPSF3K_RS08540 a65391e4718b1a5ded0f361653c4172f 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site SPSF3K_RS08540 a65391e4718b1a5ded0f361653c4172f 87 Gene3D G3DSA:3.30.1340.10 1 87 5.6E-32 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SPSF3K_RS08540 a65391e4718b1a5ded0f361653c4172f 87 PRINTS PR00107 Phosphocarrier protein signature 53 70 7.4E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SPSF3K_RS08540 a65391e4718b1a5ded0f361653c4172f 87 PRINTS PR00107 Phosphocarrier protein signature 38 53 7.4E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SPSF3K_RS08540 a65391e4718b1a5ded0f361653c4172f 87 PRINTS PR00107 Phosphocarrier protein signature 13 29 7.4E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SPSF3K_RS08540 a65391e4718b1a5ded0f361653c4172f 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 2.5E-32 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like SPSF3K_RS08540 a65391e4718b1a5ded0f361653c4172f 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site SPSF3K_RS05295 915361e69e8bc4d426feef6fb3e0479e 242 SUPERFAMILY SSF75217 1 239 1.94E-93 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SPSF3K_RS05295 915361e69e8bc4d426feef6fb3e0479e 242 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 242 105.299 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SPSF3K_RS05295 915361e69e8bc4d426feef6fb3e0479e 242 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 227 3.8E-91 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SPSF3K_RS05295 915361e69e8bc4d426feef6fb3e0479e 242 PIRSF PIRSF000386 1 242 1.1E-96 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SPSF3K_RS05295 915361e69e8bc4d426feef6fb3e0479e 242 Gene3D G3DSA:3.40.1280.10 1 163 1.2E-71 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPSF3K_RS05295 915361e69e8bc4d426feef6fb3e0479e 242 Gene3D G3DSA:1.10.1270.20 164 242 5.4E-34 T 29-03-2018 SPSF3K_RS05295 915361e69e8bc4d426feef6fb3e0479e 242 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 215 2.8E-66 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SPSF3K_RS10990 3f923a599770204684cb1297dd052c20 325 Pfam PF06458 MucBP domain 108 169 2.1E-19 T 29-03-2018 IPR009459 MucBP domain SPSF3K_RS10990 3f923a599770204684cb1297dd052c20 325 Pfam PF06458 MucBP domain 177 240 1.7E-17 T 29-03-2018 IPR009459 MucBP domain SPSF3K_RS10990 3f923a599770204684cb1297dd052c20 325 Pfam PF00746 LPXTG cell wall anchor motif 286 324 2.8E-6 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor SPSF3K_RS10990 3f923a599770204684cb1297dd052c20 325 TIGRFAM TIGR02167 Liste_lipo_26: bacterial surface protein 26-residue repeat 8 25 1.6E-6 T 29-03-2018 IPR011889 Bacterial surface protein 26-residue repeat SPSF3K_RS10990 3f923a599770204684cb1297dd052c20 325 Gene3D G3DSA:3.10.20.320 175 257 4.3E-22 T 29-03-2018 SPSF3K_RS10990 3f923a599770204684cb1297dd052c20 325 Gene3D G3DSA:3.10.20.320 100 174 4.4E-23 T 29-03-2018 SPSF3K_RS10990 3f923a599770204684cb1297dd052c20 325 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 291 324 1.8E-5 T 29-03-2018 SPSF3K_RS00300 d719eff4d566ea898a6adb690a3b2700 60 SUPERFAMILY SSF57829 2 54 4.15E-16 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SPSF3K_RS00300 d719eff4d566ea898a6adb690a3b2700 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 8.5E-19 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00300 d719eff4d566ea898a6adb690a3b2700 60 Pfam PF01783 Ribosomal L32p protein family 2 54 1.1E-18 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00300 d719eff4d566ea898a6adb690a3b2700 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.158 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS08045 f71bf2fc746f363509c4c338abace187 332 Pfam PF04392 ABC transporter substrate binding protein 39 327 1.6E-102 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein SPSF3K_RS08045 f71bf2fc746f363509c4c338abace187 332 Gene3D G3DSA:3.40.50.2300 159 296 1.5E-22 T 29-03-2018 SPSF3K_RS08045 f71bf2fc746f363509c4c338abace187 332 SUPERFAMILY SSF53822 37 261 8.7E-14 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS08045 f71bf2fc746f363509c4c338abace187 332 Gene3D G3DSA:3.40.50.2300 36 158 8.3E-18 T 29-03-2018 SPSF3K_RS10515 1d1fcb71c1f94740c94386cf5d13c455 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 36.162 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10515 1d1fcb71c1f94740c94386cf5d13c455 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 2.4E-77 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10515 1d1fcb71c1f94740c94386cf5d13c455 207 SUPERFAMILY SSF52166 1 206 6.15E-78 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10515 1d1fcb71c1f94740c94386cf5d13c455 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 3.9E-66 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10515 1d1fcb71c1f94740c94386cf5d13c455 207 Gene3D G3DSA:3.40.1370.10 2 145 2.3E-55 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10515 1d1fcb71c1f94740c94386cf5d13c455 207 Gene3D G3DSA:3.40.1370.10 146 205 4.2E-12 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS03255 6913e20e632f1ff44ccd1b27765446a7 300 Gene3D G3DSA:3.40.50.300 100 294 1.6E-18 T 29-03-2018 SPSF3K_RS03255 6913e20e632f1ff44ccd1b27765446a7 300 Pfam PF07319 Primosomal protein DnaI N-terminus 1 90 3.9E-23 T 29-03-2018 IPR009928 Primosomal DnaI, N-terminal SPSF3K_RS03255 6913e20e632f1ff44ccd1b27765446a7 300 SUPERFAMILY SSF52540 116 268 2.96E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03255 6913e20e632f1ff44ccd1b27765446a7 300 Pfam PF01695 IstB-like ATP binding protein 105 265 1.2E-13 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 SPSF3K_RS03540 342be40b87a22f3be51acc0dd2f2aa68 311 SUPERFAMILY SSF64182 3 310 4.97E-83 T 29-03-2018 SPSF3K_RS03540 342be40b87a22f3be51acc0dd2f2aa68 311 Pfam PF01368 DHH family 3 147 8.9E-25 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SPSF3K_RS03540 342be40b87a22f3be51acc0dd2f2aa68 311 Gene3D G3DSA:3.90.1640.10 1 190 2.6E-60 T 29-03-2018 SPSF3K_RS03540 342be40b87a22f3be51acc0dd2f2aa68 311 Pfam PF02833 DHHA2 domain 185 307 3.0E-17 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SPSF3K_RS03540 342be40b87a22f3be51acc0dd2f2aa68 311 SMART SM01131 183 309 1.5E-56 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SPSF3K_RS03540 342be40b87a22f3be51acc0dd2f2aa68 311 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 311 44.257 T 29-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SPSF3K_RS02170 3652e70982d9b372e2ef8623928afba6 238 Gene3D G3DSA:3.40.50.300 1 238 4.1E-59 T 29-03-2018 SPSF3K_RS02170 3652e70982d9b372e2ef8623928afba6 238 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS02170 3652e70982d9b372e2ef8623928afba6 238 Pfam PF00005 ABC transporter 20 161 3.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS02170 3652e70982d9b372e2ef8623928afba6 238 SMART SM00382 29 217 2.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02170 3652e70982d9b372e2ef8623928afba6 238 SUPERFAMILY SSF52540 7 224 1.93E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08895 c7ce6d61fb519a0d8d5c04f41db25089 264 SUPERFAMILY SSF55174 183 254 2.24E-27 T 29-03-2018 SPSF3K_RS08895 c7ce6d61fb519a0d8d5c04f41db25089 264 SUPERFAMILY SSF55174 40 131 2.24E-27 T 29-03-2018 SPSF3K_RS08895 c7ce6d61fb519a0d8d5c04f41db25089 264 Gene3D G3DSA:3.10.290.10 185 238 1.6E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08895 c7ce6d61fb519a0d8d5c04f41db25089 264 Pfam PF01479 S4 domain 187 232 7.1E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08895 c7ce6d61fb519a0d8d5c04f41db25089 264 SMART SM00363 186 243 1.1E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS02065 194886df5708ec580b9642bb90383456 586 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 562 582 1.4E-7 T 29-03-2018 IPR019950 M protein-type anchor domain SPSF3K_RS02065 194886df5708ec580b9642bb90383456 586 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 545 560 1.4E-7 T 29-03-2018 IPR019950 M protein-type anchor domain SPSF3K_RS02065 194886df5708ec580b9642bb90383456 586 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 551 584 0.0011 T 29-03-2018 SPSF3K_RS02065 194886df5708ec580b9642bb90383456 586 Pfam PF00746 LPXTG cell wall anchor motif 544 585 6.1E-9 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor SPSF3K_RS02065 194886df5708ec580b9642bb90383456 586 Gene3D G3DSA:1.20.5.340 381 483 3.9E-10 T 29-03-2018 SPSF3K_RS02065 194886df5708ec580b9642bb90383456 586 SUPERFAMILY SSF57997 261 486 1.96E-6 T 29-03-2018 SPSF3K_RS02065 194886df5708ec580b9642bb90383456 586 Gene3D G3DSA:1.20.5.170 290 380 9.2E-7 T 29-03-2018 SPSF3K_RS02065 194886df5708ec580b9642bb90383456 586 Gene3D G3DSA:1.10.287.620 135 269 0.12 T 29-03-2018 SPSF3K_RS02065 194886df5708ec580b9642bb90383456 586 Gene3D G3DSA:1.20.5.320 484 521 0.0081 T 29-03-2018 SPSF3K_RS09590 3b2b31f08ba900658ec86f048a0e43ab 182 SUPERFAMILY SSF69754 4 114 6.02E-31 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SPSF3K_RS09590 3b2b31f08ba900658ec86f048a0e43ab 182 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 124 178 4.5E-25 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal SPSF3K_RS09590 3b2b31f08ba900658ec86f048a0e43ab 182 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 182 24.909 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid SPSF3K_RS09590 3b2b31f08ba900658ec86f048a0e43ab 182 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 96 1.1E-27 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SPSF3K_RS09590 3b2b31f08ba900658ec86f048a0e43ab 182 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 4 103 4.9E-29 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SPSF3K_RS09590 3b2b31f08ba900658ec86f048a0e43ab 182 Gene3D G3DSA:3.30.160.100 1 103 6.1E-27 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SPSF3K_RS07810 40cc0b31add3acdd6f297c3ef662f08f 267 SUPERFAMILY SSF56784 1 265 2.46E-65 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07810 40cc0b31add3acdd6f297c3ef662f08f 267 Gene3D G3DSA:3.40.50.1000 3 99 1.6E-8 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07810 40cc0b31add3acdd6f297c3ef662f08f 267 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 261 1.7E-57 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07810 40cc0b31add3acdd6f297c3ef662f08f 267 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 261 4.5E-51 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS07810 40cc0b31add3acdd6f297c3ef662f08f 267 Gene3D G3DSA:3.30.1240.10 100 191 9.9E-22 T 29-03-2018 SPSF3K_RS07810 40cc0b31add3acdd6f297c3ef662f08f 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 234 1.2E-18 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS07330 56e5a82e7a2d38034c5cf2641a910302 717 SUPERFAMILY SSF52266 508 699 2.33E-19 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SPSF3K_RS07330 56e5a82e7a2d38034c5cf2641a910302 717 Gene3D G3DSA:3.90.20.10 121 237 5.8E-4 T 29-03-2018 SPSF3K_RS07330 56e5a82e7a2d38034c5cf2641a910302 717 Gene3D G3DSA:2.70.50.60 16 108 0.18 T 29-03-2018 SPSF3K_RS07330 56e5a82e7a2d38034c5cf2641a910302 717 Gene3D G3DSA:3.40.50.1110 505 709 3.0E-19 T 29-03-2018 SPSF3K_RS07330 56e5a82e7a2d38034c5cf2641a910302 717 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 512 685 1.4E-10 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SPSF3K_RS08360 15120c2e0b2c110bddd024309b82594f 137 Pfam PF03061 Thioesterase superfamily 39 112 1.3E-17 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SPSF3K_RS08360 15120c2e0b2c110bddd024309b82594f 137 Gene3D G3DSA:3.10.129.10 4 129 8.3E-24 T 29-03-2018 SPSF3K_RS08360 15120c2e0b2c110bddd024309b82594f 137 SUPERFAMILY SSF54637 14 125 7.64E-26 T 29-03-2018 IPR029069 HotDog domain SPSF3K_RS08360 15120c2e0b2c110bddd024309b82594f 137 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 121 1.2E-17 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 7 151 3.4E-53 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 SUPERFAMILY SSF63411 7 158 3.75E-60 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 PIRSF PIRSF006160 4 160 3.7E-63 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 Gene3D G3DSA:3.30.1360.80 6 158 2.0E-56 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 4 158 34.693 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 120 139 1.4E-32 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 8 26 1.4E-32 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 31 49 1.4E-32 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 52 70 1.4E-32 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 76 94 1.4E-32 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09690 d36d080b4b85f052a9987bc14a57423c 160 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 11 153 3.0E-70 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS09800 631a3c11060dec38a5b452623a95f304 416 Gene3D G3DSA:3.40.605.10 3 233 1.0E-38 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS09800 631a3c11060dec38a5b452623a95f304 416 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 405 1.2E-151 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SPSF3K_RS09800 631a3c11060dec38a5b452623a95f304 416 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 415 40.368 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SPSF3K_RS09800 631a3c11060dec38a5b452623a95f304 416 Pfam PF00171 Aldehyde dehydrogenase family 9 282 6.9E-14 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS09800 631a3c11060dec38a5b452623a95f304 416 Pfam PF00171 Aldehyde dehydrogenase family 316 378 1.2E-5 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS09800 631a3c11060dec38a5b452623a95f304 416 SUPERFAMILY SSF53720 4 415 5.11E-110 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS09800 631a3c11060dec38a5b452623a95f304 416 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 322 344 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SPSF3K_RS09800 631a3c11060dec38a5b452623a95f304 416 PIRSF PIRSF000151 1 416 2.0E-177 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SPSF3K_RS09800 631a3c11060dec38a5b452623a95f304 416 Gene3D G3DSA:3.40.605.10 234 416 4.2E-37 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS01875 ca3c8b2ac7d91c739df29037d17caf5a 572 SMART SM00382 356 543 8.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS01875 ca3c8b2ac7d91c739df29037d17caf5a 572 Pfam PF00005 ABC transporter 354 497 9.2E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS01875 ca3c8b2ac7d91c739df29037d17caf5a 572 SUPERFAMILY SSF90123 14 297 8.5E-42 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS01875 ca3c8b2ac7d91c739df29037d17caf5a 572 Pfam PF00664 ABC transporter transmembrane region 22 278 6.0E-25 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS01875 ca3c8b2ac7d91c739df29037d17caf5a 572 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS01875 ca3c8b2ac7d91c739df29037d17caf5a 572 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 13 539 4.2E-170 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 SPSF3K_RS01875 ca3c8b2ac7d91c739df29037d17caf5a 572 Gene3D G3DSA:1.20.1560.10 5 314 1.3E-30 T 29-03-2018 SPSF3K_RS01875 ca3c8b2ac7d91c739df29037d17caf5a 572 Gene3D G3DSA:3.40.50.300 315 567 1.4E-60 T 29-03-2018 SPSF3K_RS01875 ca3c8b2ac7d91c739df29037d17caf5a 572 SUPERFAMILY SSF52540 325 564 7.88E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01120 ecdf1ad083f984de3fb1675ef9e69a76 257 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 4 255 2.7E-83 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 SPSF3K_RS01120 ecdf1ad083f984de3fb1675ef9e69a76 257 Pfam PF01026 TatD related DNase 5 255 1.3E-79 T 29-03-2018 IPR001130 TatD family GO:0016788 SPSF3K_RS01120 ecdf1ad083f984de3fb1675ef9e69a76 257 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 4 12 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 SPSF3K_RS01120 ecdf1ad083f984de3fb1675ef9e69a76 257 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 107 257 0.004 T 29-03-2018 SPSF3K_RS01120 ecdf1ad083f984de3fb1675ef9e69a76 257 SUPERFAMILY SSF51556 2 256 1.76E-88 T 29-03-2018 IPR032466 Metal-dependent hydrolase SPSF3K_RS01120 ecdf1ad083f984de3fb1675ef9e69a76 257 PIRSF PIRSF005902 1 257 4.5E-79 T 29-03-2018 IPR001130 TatD family GO:0016788 SPSF3K_RS01120 ecdf1ad083f984de3fb1675ef9e69a76 257 Gene3D G3DSA:3.20.20.140 2 257 1.8E-83 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 319 325 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00941 Cadmium-transporting ATPase signature 182 198 1.4E-9 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00941 Cadmium-transporting ATPase signature 201 215 1.4E-9 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00941 Cadmium-transporting ATPase signature 100 120 1.4E-9 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00941 Cadmium-transporting ATPase signature 28 45 1.4E-9 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00941 Cadmium-transporting ATPase signature 45 57 1.4E-9 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 Pfam PF00122 E1-E2 ATPase 116 297 1.9E-38 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 65 406 1.2E-97 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 Gene3D G3DSA:1.20.1110.10 14 343 1.0E-29 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 Pfam PF00702 haloacid dehalogenase-like hydrolase 313 526 1.0E-42 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 SUPERFAMILY SSF81653 123 216 8.11E-20 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 88 591 6.8E-81 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 Gene3D G3DSA:3.40.1110.10 344 438 4.2E-15 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 166 180 6.4E-23 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 317 331 6.4E-23 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 469 6.4E-23 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 531 6.4E-23 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 547 6.4E-23 T 29-03-2018 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 SUPERFAMILY SSF56784 409 610 6.19E-50 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 SUPERFAMILY SSF56784 316 335 6.19E-50 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 SUPERFAMILY SSF81665 67 119 2.62E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 SUPERFAMILY SSF81665 560 588 2.62E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 SUPERFAMILY SSF81665 217 311 2.62E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 Gene3D G3DSA:3.40.50.1000 439 577 3.6E-35 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08775 302717a839cd4a5a7f7136b17d122d27 617 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 65 613 2.7E-176 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 SPSF3K_RS06485 a2c44da7af3f981bf21faf2eebb6f21f 105 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 87 2.8E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS06485 a2c44da7af3f981bf21faf2eebb6f21f 105 SUPERFAMILY SSF52794 1 89 3.66E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS06485 a2c44da7af3f981bf21faf2eebb6f21f 105 Gene3D G3DSA:3.40.50.2300 1 104 7.2E-21 T 29-03-2018 SPSF3K_RS02620 8e39dfce380d59c123794a57c961214d 387 Pfam PF07690 Major Facilitator Superfamily 17 264 1.4E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS02620 8e39dfce380d59c123794a57c961214d 387 Gene3D G3DSA:1.20.1250.20 1 194 1.3E-21 T 29-03-2018 SPSF3K_RS02620 8e39dfce380d59c123794a57c961214d 387 SUPERFAMILY SSF103473 9 378 1.7E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS02620 8e39dfce380d59c123794a57c961214d 387 Gene3D G3DSA:1.20.1250.20 198 385 7.6E-13 T 29-03-2018 SPSF3K_RS02620 8e39dfce380d59c123794a57c961214d 387 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SPSF3K_RS00670 ba3e21acfde5161bb382ffb74d7528b2 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 2.9E-19 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPSF3K_RS00670 ba3e21acfde5161bb382ffb74d7528b2 94 Gene3D G3DSA:2.30.33.40 1 94 1.3E-20 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPSF3K_RS00670 ba3e21acfde5161bb382ffb74d7528b2 94 PRINTS PR00297 10kDa chaperonin signature 24 45 2.4E-13 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPSF3K_RS00670 ba3e21acfde5161bb382ffb74d7528b2 94 PRINTS PR00297 10kDa chaperonin signature 60 72 2.4E-13 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPSF3K_RS00670 ba3e21acfde5161bb382ffb74d7528b2 94 PRINTS PR00297 10kDa chaperonin signature 2 17 2.4E-13 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPSF3K_RS00670 ba3e21acfde5161bb382ffb74d7528b2 94 PRINTS PR00297 10kDa chaperonin signature 80 93 2.4E-13 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPSF3K_RS00670 ba3e21acfde5161bb382ffb74d7528b2 94 SMART SM00883 1 93 2.5E-30 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPSF3K_RS00670 ba3e21acfde5161bb382ffb74d7528b2 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 SPSF3K_RS00670 ba3e21acfde5161bb382ffb74d7528b2 94 SUPERFAMILY SSF50129 1 93 4.36E-20 T 29-03-2018 IPR011032 GroES-like SPSF3K_RS09135 30dd39d6f25397c4e8a720577b36aafa 114 Gene3D G3DSA:1.10.287.620 2 107 5.2E-4 T 29-03-2018 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 3.9E-20 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 3.9E-20 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 3.9E-20 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 3.9E-20 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 78 22.389 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 SUPERFAMILY SSF46911 6 78 1.14E-29 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 78 5.0E-24 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 77 7.4E-31 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 Gene3D G3DSA:4.10.640.10 1 79 6.2E-32 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01635 2a69671f2fbaced90c10a0c738d12d87 79 Pfam PF01084 Ribosomal protein S18 22 73 1.3E-27 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00825 4208bf9eef1cc1ab6a9e270ac2339e13 103 Pfam PF05495 CHY zinc finger 14 87 1.8E-9 T 29-03-2018 IPR008913 Zinc finger, CHY-type GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 SPSF3K_RS00825 4208bf9eef1cc1ab6a9e270ac2339e13 103 SUPERFAMILY SSF161219 4 85 5.1E-16 T 29-03-2018 SPSF3K_RS00825 4208bf9eef1cc1ab6a9e270ac2339e13 103 PIRSF PIRSF017292 1 101 5.9E-33 T 29-03-2018 IPR016694 Protein of unknown function UCP017292, zinc finger, CHY-type SPSF3K_RS06975 1a98b2d14b760881f43a8fd805a06826 182 Gene3D G3DSA:3.40.50.1950 2 181 1.2E-51 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SPSF3K_RS06975 1a98b2d14b760881f43a8fd805a06826 182 SUPERFAMILY SSF52507 4 176 1.44E-54 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SPSF3K_RS06975 1a98b2d14b760881f43a8fd805a06826 182 TIGRFAM TIGR02113 coaC_strep: phosphopantothenoylcysteine decarboxylase 4 176 2.0E-91 T 29-03-2018 IPR011847 Phosphopantothenoylcysteine decarboxylase KEGG: 00770+4.1.1.36|MetaCyc: PWY-7851 SPSF3K_RS06975 1a98b2d14b760881f43a8fd805a06826 182 Pfam PF02441 Flavoprotein 4 177 6.2E-44 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 Gene3D G3DSA:3.50.50.60 251 314 2.2E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 2.2E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.2E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 2.2E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.2E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 2.2E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 Gene3D G3DSA:3.30.390.30 323 440 1.7E-7 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 SUPERFAMILY SSF51905 1 312 1.69E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 7.6E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 379 394 7.6E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 7.6E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 7.6E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 319 340 7.6E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 7.6E-18 T 29-03-2018 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 Gene3D G3DSA:3.50.50.60 129 239 3.5E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 Gene3D G3DSA:3.50.50.60 1 128 7.9E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 SUPERFAMILY SSF55424 323 434 9.45E-15 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS09840 0f13181b7d3526d2255555b956aac376 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 301 1.6E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06325 3a441ba102cf8c8493df79e08548c6a3 509 Gene3D G3DSA:3.40.190.10 391 508 4.9E-24 T 29-03-2018 SPSF3K_RS06325 3a441ba102cf8c8493df79e08548c6a3 509 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 209 4.0E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS06325 3a441ba102cf8c8493df79e08548c6a3 509 Gene3D G3DSA:1.10.3720.10 9 210 2.0E-30 T 29-03-2018 SPSF3K_RS06325 3a441ba102cf8c8493df79e08548c6a3 509 SUPERFAMILY SSF53850 239 507 2.39E-72 T 29-03-2018 SPSF3K_RS06325 3a441ba102cf8c8493df79e08548c6a3 509 SUPERFAMILY SSF161098 17 200 1.96E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS06325 3a441ba102cf8c8493df79e08548c6a3 509 Gene3D G3DSA:3.40.190.10 229 390 2.2E-33 T 29-03-2018 SPSF3K_RS06325 3a441ba102cf8c8493df79e08548c6a3 509 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 239 502 5.5E-65 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SPSF3K_RS06305 57b1e63b43c7dd928381d19a2e55faca 280 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 273 1.7E-55 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS06305 57b1e63b43c7dd928381d19a2e55faca 280 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 274 2.7E-57 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS06305 57b1e63b43c7dd928381d19a2e55faca 280 Gene3D G3DSA:3.40.50.1000 1 17 0.064 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS06305 57b1e63b43c7dd928381d19a2e55faca 280 SUPERFAMILY SSF56784 4 277 6.67E-55 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS06305 57b1e63b43c7dd928381d19a2e55faca 280 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 247 9.0E-23 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS06305 57b1e63b43c7dd928381d19a2e55faca 280 Gene3D G3DSA:3.40.50.1000 18 280 5.8E-34 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS05065 c7fd84dc094cdcf5fcf010edbcb61009 310 SUPERFAMILY SSF53448 4 253 3.66E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS05065 c7fd84dc094cdcf5fcf010edbcb61009 310 Gene3D G3DSA:3.90.550.10 2 235 3.8E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS05065 c7fd84dc094cdcf5fcf010edbcb61009 310 Pfam PF00535 Glycosyl transferase family 2 7 159 2.0E-18 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SPSF3K_RS02650 e728b8f2c142995fdbd1fb76f2015d3c 131 SUPERFAMILY SSF69065 5 129 8.2E-43 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SPSF3K_RS02650 e728b8f2c142995fdbd1fb76f2015d3c 131 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 3 129 28.515 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family SPSF3K_RS02650 e728b8f2c142995fdbd1fb76f2015d3c 131 Pfam PF00636 Ribonuclease III domain 14 108 2.2E-13 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SPSF3K_RS02650 e728b8f2c142995fdbd1fb76f2015d3c 131 Gene3D G3DSA:1.10.1520.10 4 131 1.2E-18 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 SPSF3K_RS02650 e728b8f2c142995fdbd1fb76f2015d3c 131 PIRSF PIRSF005520 1 131 3.2E-50 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family SPSF3K_RS01490 552b5dc9f8b39c7a43ee106939967a8a 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 299 4.7E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01490 552b5dc9f8b39c7a43ee106939967a8a 305 SUPERFAMILY SSF161098 63 289 2.35E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01490 552b5dc9f8b39c7a43ee106939967a8a 305 Gene3D G3DSA:1.10.3720.10 19 304 2.5E-35 T 29-03-2018 SPSF3K_RS04505 5c026c06bc55ee319a738354bd805479 638 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 1 638 33.884 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SPSF3K_RS04505 5c026c06bc55ee319a738354bd805479 638 PIRSF PIRSF000906 1 638 3.8E-262 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SPSF3K_RS04505 5c026c06bc55ee319a738354bd805479 638 SUPERFAMILY SSF56300 171 226 1.22E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS04505 5c026c06bc55ee319a738354bd805479 638 SUPERFAMILY SSF56300 382 417 1.22E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS04505 5c026c06bc55ee319a738354bd805479 638 SUPERFAMILY SSF56300 504 556 1.22E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS04505 5c026c06bc55ee319a738354bd805479 638 SUPERFAMILY SSF56300 453 469 1.22E-10 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS04505 5c026c06bc55ee319a738354bd805479 638 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 3 635 1.9E-250 T 29-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 SPSF3K_RS04505 5c026c06bc55ee319a738354bd805479 638 Gene3D G3DSA:3.60.21.10 16 565 1.1E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS09450 14cde9a986fa0efbdb9cfa704ceaf4a9 192 SMART SM00987 27 184 3.0E-17 T 29-03-2018 SPSF3K_RS09450 14cde9a986fa0efbdb9cfa704ceaf4a9 192 Gene3D G3DSA:3.40.470.10 2 192 3.3E-35 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS09450 14cde9a986fa0efbdb9cfa704ceaf4a9 192 SUPERFAMILY SSF52141 3 191 1.47E-42 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS09450 14cde9a986fa0efbdb9cfa704ceaf4a9 192 Pfam PF03167 Uracil DNA glycosylase superfamily 30 180 1.8E-20 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS09450 14cde9a986fa0efbdb9cfa704ceaf4a9 192 SMART SM00986 27 184 3.0E-17 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS05930 2607bc5009af0da324897e1eae34cb00 372 Gene3D G3DSA:3.20.20.210 4 372 1.7E-93 T 29-03-2018 SPSF3K_RS05930 2607bc5009af0da324897e1eae34cb00 372 SUPERFAMILY SSF51726 7 370 4.58E-81 T 29-03-2018 SPSF3K_RS05930 2607bc5009af0da324897e1eae34cb00 372 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 9 67 2.0E-4 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SPSF3K_RS05930 2607bc5009af0da324897e1eae34cb00 372 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 161 344 1.6E-7 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 SPSF3K_RS02460 68ffe500cb4be033b693e4693c49c5fe 271 Gene3D G3DSA:3.60.10.10 2 271 2.2E-28 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SPSF3K_RS02460 68ffe500cb4be033b693e4693c49c5fe 271 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 19 263 2.6E-8 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SPSF3K_RS02460 68ffe500cb4be033b693e4693c49c5fe 271 SUPERFAMILY SSF56219 3 270 8.38E-30 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SPSF3K_RS10855 43a66a1069f04f9c77dbac3984fe1849 180 Pfam PF00156 Phosphoribosyl transferase domain 11 160 4.4E-23 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPSF3K_RS10855 43a66a1069f04f9c77dbac3984fe1849 180 SUPERFAMILY SSF53271 4 178 8.39E-59 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS10855 43a66a1069f04f9c77dbac3984fe1849 180 Gene3D G3DSA:3.40.50.2020 1 180 1.1E-46 T 29-03-2018 SPSF3K_RS10855 43a66a1069f04f9c77dbac3984fe1849 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 174 1.6E-63 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 PRINTS PR00131 Glycosyl hydrolase family 1 signature 324 338 3.8E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 PRINTS PR00131 Glycosyl hydrolase family 1 signature 456 468 3.8E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 397 3.8E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 421 3.8E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 PRINTS PR00131 Glycosyl hydrolase family 1 signature 431 448 3.8E-13 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 SUPERFAMILY SSF51445 3 42 1.01E-152 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 SUPERFAMILY SSF51445 82 492 1.01E-152 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 Gene3D G3DSA:3.20.20.80 3 494 1.9E-143 T 29-03-2018 SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 Pfam PF00232 Glycosyl hydrolase family 1 88 491 1.1E-111 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06185 b4ab8822a134b6ed1b10eb2d7b6a531b 495 Pfam PF00232 Glycosyl hydrolase family 1 4 37 4.0E-9 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 Gene3D G3DSA:3.40.1770.10 88 230 6.8E-20 T 29-03-2018 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 Gene3D G3DSA:3.40.1770.10 278 651 2.3E-145 T 29-03-2018 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 SUPERFAMILY SSF111326 82 652 1.1E-224 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 PIRSF PIRSF001423 73 664 1.5E-179 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 Pfam PF17392 Urocanase C-terminal domain 447 643 1.7E-81 T 29-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 Pfam PF01175 Urocanase Rossmann-like domain 219 442 3.8E-81 T 29-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 ProSitePatterns PS01233 Urocanase signature. 540 555 - T 29-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 TIGRFAM TIGR01228 hutU: urocanate hydratase 104 645 3.4E-129 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 Hamap MF_00577 Urocanate hydratase [hutU]. 61 660 43.903 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04330 954ca347e8f925517fa2837c1d0e984a 677 Pfam PF17391 Urocanase N-terminal domain 90 216 1.9E-50 T 29-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS03360 33b8da11d822ef09c7953f12e94be150 183 Pfam PF04079 Segregation and condensation complex subunit ScpB 6 164 8.6E-52 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SPSF3K_RS03360 33b8da11d822ef09c7953f12e94be150 183 Gene3D G3DSA:1.10.10.10 1 85 1.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03360 33b8da11d822ef09c7953f12e94be150 183 PIRSF PIRSF019345 1 183 9.9E-49 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SPSF3K_RS03360 33b8da11d822ef09c7953f12e94be150 183 Gene3D G3DSA:1.10.10.10 86 156 1.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03360 33b8da11d822ef09c7953f12e94be150 183 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 179 33.213 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SPSF3K_RS03360 33b8da11d822ef09c7953f12e94be150 183 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 5 181 1.7E-44 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SPSF3K_RS03360 33b8da11d822ef09c7953f12e94be150 183 SUPERFAMILY SSF46785 83 157 2.52E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03360 33b8da11d822ef09c7953f12e94be150 183 SUPERFAMILY SSF46785 3 78 8.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08190 bcbf2adf77e7bf094124a2c1dbb53413 328 SMART SM00450 120 221 4.1E-19 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS08190 bcbf2adf77e7bf094124a2c1dbb53413 328 SUPERFAMILY SSF52821 110 251 1.06E-32 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS08190 bcbf2adf77e7bf094124a2c1dbb53413 328 Pfam PF12368 Rhodanase C-terminal 228 293 3.4E-13 T 29-03-2018 IPR022111 Rhodanase, C-terminal SPSF3K_RS08190 bcbf2adf77e7bf094124a2c1dbb53413 328 Pfam PF00581 Rhodanese-like domain 121 217 4.1E-11 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS08190 bcbf2adf77e7bf094124a2c1dbb53413 328 Hamap MF_00469 UPF0176 protein YceA [yceA]. 3 272 39.328 T 29-03-2018 IPR020936 Uncharacterised protein family UPF0176 SPSF3K_RS08190 bcbf2adf77e7bf094124a2c1dbb53413 328 Gene3D G3DSA:3.40.250.10 114 232 7.0E-25 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 SUPERFAMILY SSF51246 332 445 2.88E-41 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 SUPERFAMILY SSF52440 1 113 1.94E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 4.1E-207 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 4.0E-73 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 SUPERFAMILY SSF56059 83 353 1.48E-68 T 29-03-2018 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 Gene3D G3DSA:3.30.1490.20 129 201 1.2E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 5.4E-45 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 Gene3D G3DSA:3.40.50.20 1 128 6.8E-52 T 29-03-2018 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 SMART SM00878 337 444 5.8E-59 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 Pfam PF02785 Biotin carboxylase C-terminal domain 337 444 1.9E-38 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPSF3K_RS10070 ce9956ac86fb62d21a4afd1dee8daa02 454 Gene3D G3DSA:3.30.470.20 204 447 3.5E-98 T 29-03-2018 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 327 2.8E-55 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 6.3E-44 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 Gene3D G3DSA:3.40.50.1370 6 162 3.8E-54 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 Gene3D G3DSA:3.40.50.1370 163 331 6.1E-54 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 SUPERFAMILY SSF53671 5 331 2.88E-102 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 329 1.2E-124 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 294 317 3.6E-23 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 3.6E-23 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 3.6E-23 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 3.6E-23 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 7.0E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 7.0E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 308 319 7.0E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 7.0E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 7.0E-28 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS09070 e472210f9d89c17f84f0ec0ed26fadab 337 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 330 80.411 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SPSF3K_RS04380 2499980586863483af3ff536525bf3ed 300 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 202 5.6E-27 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04380 2499980586863483af3ff536525bf3ed 300 Gene3D G3DSA:3.40.50.1000 1 221 1.7E-31 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04380 2499980586863483af3ff536525bf3ed 300 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 7.7E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS04380 2499980586863483af3ff536525bf3ed 300 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 7.7E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS04380 2499980586863483af3ff536525bf3ed 300 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 7.7E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS04380 2499980586863483af3ff536525bf3ed 300 SUPERFAMILY SSF56784 1 232 8.54E-44 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04380 2499980586863483af3ff536525bf3ed 300 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 197 4.1E-16 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS08790 d56455e73dcbbe965cc7084c5407d323 277 Gene3D G3DSA:3.40.50.1110 43 277 5.6E-36 T 29-03-2018 SPSF3K_RS08790 d56455e73dcbbe965cc7084c5407d323 277 SUPERFAMILY SSF52266 47 274 1.34E-38 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SPSF3K_RS08790 d56455e73dcbbe965cc7084c5407d323 277 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 52 262 7.1E-28 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SPSF3K_RS01960 6b3829dcf96de6fb62c3b9ada4809e28 145 Pfam PF15980 Putative Competence protein ComGF 40 134 1.0E-18 T 29-03-2018 IPR016977 Competence operon G, ComGF SPSF3K_RS01960 6b3829dcf96de6fb62c3b9ada4809e28 145 PIRSF PIRSF031611 1 145 1.2E-46 T 29-03-2018 IPR016977 Competence operon G, ComGF SPSF3K_RS07360 ce0614696bfea52ae35d3cac34bc99b5 124 Pfam PF05657 Protein of unknown function (DUF806) 4 120 2.7E-32 T 29-03-2018 IPR008524 Protein of unknown function DUF806 SPSF3K_RS02975 e04d2479a37cdb199219eee901d1bcd6 554 SMART SM01120 34 199 6.8E-69 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SPSF3K_RS02975 e04d2479a37cdb199219eee901d1bcd6 554 Pfam PF02734 DAK2 domain 34 198 4.5E-41 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SPSF3K_RS02975 e04d2479a37cdb199219eee901d1bcd6 554 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 9 554 2.2E-212 T 29-03-2018 IPR019986 DAK2 domain-containing protein YloV SPSF3K_RS02975 e04d2479a37cdb199219eee901d1bcd6 554 SUPERFAMILY SSF101473 3 200 3.14E-47 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SPSF3K_RS02975 e04d2479a37cdb199219eee901d1bcd6 554 SMART SM01121 240 554 4.7E-190 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain SPSF3K_RS02975 e04d2479a37cdb199219eee901d1bcd6 554 Pfam PF13684 Dihydroxyacetone kinase family 240 554 1.5E-125 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain SPSF3K_RS03420 321bb41b24282fa0ea678ec95de91727 137 TIGRFAM TIGR01636 phage_rinA: phage transcriptional regulator, RinA family 8 135 1.5E-11 T 29-03-2018 IPR006523 Transcription activator RinA SPSF3K_RS03420 321bb41b24282fa0ea678ec95de91727 137 Gene3D G3DSA:1.10.10.10 72 134 6.0E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03420 321bb41b24282fa0ea678ec95de91727 137 SUPERFAMILY SSF88659 72 130 3.92E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS00575 dd87742bddbd3e41f00316cef4f67969 284 SUPERFAMILY SSF52518 8 270 1.08E-78 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SPSF3K_RS00575 dd87742bddbd3e41f00316cef4f67969 284 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 15 258 8.2E-46 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SPSF3K_RS00575 dd87742bddbd3e41f00316cef4f67969 284 Gene3D G3DSA:3.40.50.970 1 280 2.8E-66 T 29-03-2018 SPSF3K_RS08735 54537ec5f69883956ec6c942c8726bad 198 SMART SM00493 80 165 4.8E-12 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS08735 54537ec5f69883956ec6c942c8726bad 198 Pfam PF13662 Toprim domain 81 171 6.6E-22 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS08735 54537ec5f69883956ec6c942c8726bad 198 TIGRFAM TIGR00615 recR: recombination protein RecR 3 196 6.9E-81 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SPSF3K_RS08735 54537ec5f69883956ec6c942c8726bad 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 100.539 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SPSF3K_RS08735 54537ec5f69883956ec6c942c8726bad 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 SPSF3K_RS08735 54537ec5f69883956ec6c942c8726bad 198 SUPERFAMILY SSF111304 2 198 4.84E-73 T 29-03-2018 IPR023627 Recombination protein RecR SPSF3K_RS08735 54537ec5f69883956ec6c942c8726bad 198 Pfam PF02132 RecR protein 39 78 3.9E-16 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger SPSF3K_RS08735 54537ec5f69883956ec6c942c8726bad 198 Gene3D G3DSA:3.40.1360.10 77 170 5.2E-36 T 29-03-2018 SPSF3K_RS04680 88cb01a60e1c36ec7f63ef95051e83fd 226 SUPERFAMILY SSF51412 51 204 9.15E-16 T 29-03-2018 SPSF3K_RS04680 88cb01a60e1c36ec7f63ef95051e83fd 226 Gene3D G3DSA:3.20.20.70 102 205 2.3E-15 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 SMART SM00433 44 644 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 580 640 3.9E-29 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 15 649 9.8E-294 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 Pfam PF01751 Toprim domain 430 541 2.4E-17 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 12 650 88.272 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 SMART SM00387 40 184 2.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 SUPERFAMILY SSF54211 232 402 1.48E-62 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 Gene3D G3DSA:3.30.565.10 27 229 6.5E-72 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 Gene3D G3DSA:3.40.50.670 410 647 3.0E-98 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 SUPERFAMILY SSF55874 14 227 1.31E-71 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 15 25 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 231 253 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 385 405 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 323 339 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 371 385 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 481 490 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 205 218 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 190 205 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 620 636 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR01159 DNA gyrase subunit B signature 604 616 3.4E-75 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 Pfam PF00204 DNA gyrase B 232 401 1.0E-65 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 Gene3D G3DSA:3.30.230.10 231 403 4.2E-66 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 SUPERFAMILY SSF56719 405 642 5.75E-84 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 42 183 1.8E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 ProSitePatterns PS00177 DNA topoisomerase II signature. 433 441 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR00418 DNA topoisomerase II family signature 79 92 4.8E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR00418 DNA topoisomerase II family signature 515 532 4.8E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR00418 DNA topoisomerase II family signature 431 445 4.8E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR00418 DNA topoisomerase II family signature 535 547 4.8E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR00418 DNA topoisomerase II family signature 122 136 4.8E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR00418 DNA topoisomerase II family signature 279 292 4.8E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR00418 DNA topoisomerase II family signature 44 59 4.8E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR00418 DNA topoisomerase II family signature 583 599 4.8E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS04700 223a00d298006e47e83e7811291facc4 650 PRINTS PR00418 DNA topoisomerase II family signature 497 513 4.8E-68 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS09335 91b9c2f35254e7de79b0e10f1888c251 294 SUPERFAMILY SSF53223 4 110 2.65E-32 T 29-03-2018 SPSF3K_RS09335 91b9c2f35254e7de79b0e10f1888c251 294 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 11 287 6.4E-63 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SPSF3K_RS09335 91b9c2f35254e7de79b0e10f1888c251 294 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 14 96 1.8E-30 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SPSF3K_RS09335 91b9c2f35254e7de79b0e10f1888c251 294 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 9 291 32.877 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 SPSF3K_RS09335 91b9c2f35254e7de79b0e10f1888c251 294 SUPERFAMILY SSF51735 111 291 3.58E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS09335 91b9c2f35254e7de79b0e10f1888c251 294 Gene3D G3DSA:3.40.50.10860 1 121 1.0E-42 T 29-03-2018 SPSF3K_RS09335 91b9c2f35254e7de79b0e10f1888c251 294 Gene3D G3DSA:3.40.50.720 122 294 4.8E-29 T 29-03-2018 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 7.8E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 380 396 7.8E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 7.8E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 7.8E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 7.8E-38 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 Gene3D G3DSA:3.30.930.10 150 495 2.2E-103 T 29-03-2018 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 SUPERFAMILY SSF50249 8 149 1.32E-43 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 9 496 1.9E-207 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 Gene3D G3DSA:2.40.50.140 9 149 1.6E-41 T 29-03-2018 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 Pfam PF00152 tRNA synthetases class II (D, K and N) 158 495 1.4E-77 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 15 496 43.417 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 Pfam PF01336 OB-fold nucleic acid binding domain 65 138 6.7E-15 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SPSF3K_RS04375 9e12131b7d7b97aefc52e07ffacfd2a3 496 SUPERFAMILY SSF55681 156 495 3.83E-119 T 29-03-2018 SPSF3K_RS07765 282e1ef01215d75cb86aff7d4813887c 269 SUPERFAMILY SSF53167 3 269 7.51E-88 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPSF3K_RS07765 282e1ef01215d75cb86aff7d4813887c 269 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 24 266 2.4E-102 T 29-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 SPSF3K_RS07765 282e1ef01215d75cb86aff7d4813887c 269 PIRSF PIRSF000477 1 269 1.9E-105 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 SPSF3K_RS07765 282e1ef01215d75cb86aff7d4813887c 269 Pfam PF01048 Phosphorylase superfamily 24 267 2.3E-49 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPSF3K_RS07765 282e1ef01215d75cb86aff7d4813887c 269 Gene3D G3DSA:3.40.50.1580 1 269 3.2E-64 T 29-03-2018 SPSF3K_RS07765 282e1ef01215d75cb86aff7d4813887c 269 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 25 266 7.5E-102 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 SPSF3K_RS07765 282e1ef01215d75cb86aff7d4813887c 269 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 76 117 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 SPSF3K_RS00640 1a7c634bdab96d3ac657dcc827afb458 319 SUPERFAMILY SSF54593 4 304 1.25E-45 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS00640 1a7c634bdab96d3ac657dcc827afb458 319 Gene3D G3DSA:3.10.180.10 159 319 6.6E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS00640 1a7c634bdab96d3ac657dcc827afb458 319 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 182 266 4.5E-5 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPSF3K_RS00640 1a7c634bdab96d3ac657dcc827afb458 319 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 129 3.2E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPSF3K_RS00640 1a7c634bdab96d3ac657dcc827afb458 319 Gene3D G3DSA:3.10.180.10 1 158 1.4E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS06475 4d01cd21557287ddd1e2905e3a913bad 455 Gene3D G3DSA:3.20.20.80 1 454 4.2E-126 T 29-03-2018 SPSF3K_RS06475 4d01cd21557287ddd1e2905e3a913bad 455 Pfam PF00232 Glycosyl hydrolase family 1 2 449 8.6E-118 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06475 4d01cd21557287ddd1e2905e3a913bad 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 426 5.0E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06475 4d01cd21557287ddd1e2905e3a913bad 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 279 293 5.0E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06475 4d01cd21557287ddd1e2905e3a913bad 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 407 5.0E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06475 4d01cd21557287ddd1e2905e3a913bad 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 379 5.0E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06475 4d01cd21557287ddd1e2905e3a913bad 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 347 355 5.0E-14 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06475 4d01cd21557287ddd1e2905e3a913bad 455 SUPERFAMILY SSF51445 3 449 1.23E-134 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS07205 dadc8932e32d0edad173a749388a452c 412 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 289 8.1E-57 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPSF3K_RS07205 dadc8932e32d0edad173a749388a452c 412 SUPERFAMILY SSF160240 212 288 2.88E-18 T 29-03-2018 SPSF3K_RS07205 dadc8932e32d0edad173a749388a452c 412 Gene3D G3DSA:1.20.1510.10 12 207 4.0E-39 T 29-03-2018 SPSF3K_RS07205 dadc8932e32d0edad173a749388a452c 412 Gene3D G3DSA:3.30.70.1350 208 290 1.4E-17 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SPSF3K_RS07205 dadc8932e32d0edad173a749388a452c 412 Gene3D G3DSA:3.10.450.50 302 394 0.0019 T 29-03-2018 SPSF3K_RS07205 dadc8932e32d0edad173a749388a452c 412 Pfam PF01545 Cation efflux family 17 208 1.6E-45 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPSF3K_RS07205 dadc8932e32d0edad173a749388a452c 412 Pfam PF16916 Dimerisation domain of Zinc Transporter 215 288 4.2E-17 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain SPSF3K_RS07205 dadc8932e32d0edad173a749388a452c 412 SUPERFAMILY SSF161111 10 210 1.7E-48 T 29-03-2018 SPSF3K_RS00200 08bd014fc7e2871dbbe5e8b15cf99acc 193 Pfam PF08006 Protein of unknown function (DUF1700) 1 163 1.3E-20 T 29-03-2018 IPR012963 Protein of unknown function DUF1700 SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 Gene3D G3DSA:3.90.1150.10 1 76 4.7E-5 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 Pfam PF00155 Aminotransferase class I and II 32 387 5.3E-72 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 199 222 6.3E-13 T 29-03-2018 SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 163 187 6.3E-13 T 29-03-2018 SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 230 254 6.3E-13 T 29-03-2018 SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 116 137 6.3E-13 T 29-03-2018 SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 SUPERFAMILY SSF53383 1 393 3.94E-107 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 Gene3D G3DSA:3.90.1150.10 276 397 6.0E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS04540 8104f95dc81f2df5cab6749882251f23 399 Gene3D G3DSA:3.40.640.10 77 275 4.9E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 SUPERFAMILY SSF56601 1 296 1.49E-67 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 Gene3D G3DSA:2.60.410.10 298 392 8.5E-13 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 SMART SM00936 296 392 1.5E-8 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 58 69 6.6E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 114 131 6.6E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 141 154 6.6E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 296 392 1.3E-8 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 SUPERFAMILY SSF69189 288 375 7.85E-13 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 24 272 1.9E-71 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SPSF3K_RS03050 cb6c038796ea24baf30fdca5b42773ee 406 Gene3D G3DSA:3.40.710.10 20 296 3.2E-41 T 29-03-2018 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 9 645 50.295 T 29-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 SMART SM00433 40 640 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 Pfam PF01751 Toprim domain 430 540 8.9E-18 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 SUPERFAMILY SSF55874 10 219 9.3E-67 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 SUPERFAMILY SSF56719 405 646 5.49E-87 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 Gene3D G3DSA:3.40.50.670 412 644 8.8E-95 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 SMART SM00387 36 182 3.3E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 SUPERFAMILY SSF54211 229 399 4.36E-52 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 481 490 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 228 250 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 600 612 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 11 21 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 187 202 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 202 215 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 369 383 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 383 403 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 616 632 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR01159 DNA gyrase subunit B signature 319 335 2.6E-51 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 576 636 2.1E-28 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 9 648 0.0 T 29-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 ProSitePatterns PS00177 DNA topoisomerase II signature. 433 441 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 Pfam PF00204 DNA gyrase B 229 399 6.7E-56 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 181 3.8E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 Gene3D G3DSA:3.30.230.10 229 401 2.0E-53 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 Gene3D G3DSA:3.30.565.10 23 228 3.1E-69 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR00418 DNA topoisomerase II family signature 497 513 1.9E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR00418 DNA topoisomerase II family signature 431 445 1.9E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR00418 DNA topoisomerase II family signature 515 532 1.9E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR00418 DNA topoisomerase II family signature 579 595 1.9E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR00418 DNA topoisomerase II family signature 535 547 1.9E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR00418 DNA topoisomerase II family signature 75 88 1.9E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR00418 DNA topoisomerase II family signature 40 55 1.9E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR00418 DNA topoisomerase II family signature 275 288 1.9E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS07600 6918d74dfef15ae9f6fdf8de7ca9afd2 651 PRINTS PR00418 DNA topoisomerase II family signature 117 131 1.9E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 SPSF3K_RS01855 53426820d241537f4cd5bccc9eaa1a26 300 Pfam PF01040 UbiA prenyltransferase family 19 272 1.0E-21 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 SPSF3K_RS01855 53426820d241537f4cd5bccc9eaa1a26 300 PIRSF PIRSF005355 1 300 2.9E-34 T 29-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 SPSF3K_RS01545 9d83b33cf0b3201422f7ef1179660989 250 Pfam PF14506 CppA N-terminal 9 130 3.3E-56 T 29-03-2018 IPR032702 CppA, N-terminal SPSF3K_RS01545 9d83b33cf0b3201422f7ef1179660989 250 Gene3D G3DSA:3.10.180.10 12 66 0.031 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS01545 9d83b33cf0b3201422f7ef1179660989 250 SUPERFAMILY SSF54593 13 190 3.77E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS01545 9d83b33cf0b3201422f7ef1179660989 250 Gene3D G3DSA:3.10.180.40 67 191 9.7E-45 T 29-03-2018 SPSF3K_RS01545 9d83b33cf0b3201422f7ef1179660989 250 Pfam PF14507 CppA C-terminal 147 248 2.8E-32 T 29-03-2018 IPR032703 CppA, C-terminal SPSF3K_RS00280 754cf871b605075d78a3a2dcf5bc99a7 163 ProSitePatterns PS00893 Nudix box signature. 69 90 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPSF3K_RS00280 754cf871b605075d78a3a2dcf5bc99a7 163 Gene3D G3DSA:3.90.79.10 26 162 3.3E-21 T 29-03-2018 SPSF3K_RS00280 754cf871b605075d78a3a2dcf5bc99a7 163 SUPERFAMILY SSF55811 8 154 2.84E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPSF3K_RS00280 754cf871b605075d78a3a2dcf5bc99a7 163 Pfam PF00293 NUDIX domain 36 142 3.0E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SPSF3K_RS04560 4cab99a04ac966b732b1d6e4f5b78f93 325 Gene3D G3DSA:3.40.50.10680 84 325 3.8E-50 T 29-03-2018 SPSF3K_RS04560 4cab99a04ac966b732b1d6e4f5b78f93 325 SUPERFAMILY SSF142338 3 317 4.97E-97 T 29-03-2018 SPSF3K_RS04560 4cab99a04ac966b732b1d6e4f5b78f93 325 Hamap MF_00973 Gluconeogenesis factor. 2 322 33.906 T 29-03-2018 IPR010119 Gluconeogenesis factor SPSF3K_RS04560 4cab99a04ac966b732b1d6e4f5b78f93 325 Pfam PF01933 Uncharacterised protein family UPF0052 6 297 1.6E-91 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 SPSF3K_RS04560 4cab99a04ac966b732b1d6e4f5b78f93 325 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 6 320 1.4E-118 T 29-03-2018 IPR010119 Gluconeogenesis factor SPSF3K_RS01590 9be047176303e0e107539325f789ae4f 304 SUPERFAMILY SSF53098 87 299 2.28E-46 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS01590 9be047176303e0e107539325f789ae4f 304 Pfam PF01351 Ribonuclease HII 88 293 1.9E-51 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain SPSF3K_RS01590 9be047176303e0e107539325f789ae4f 304 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 300 36.233 T 29-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 SPSF3K_RS01590 9be047176303e0e107539325f789ae4f 304 Gene3D G3DSA:3.30.420.10 68 303 6.5E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS01590 9be047176303e0e107539325f789ae4f 304 PIRSF PIRSF037748 1 301 1.2E-106 T 29-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 SPSF3K_RS01590 9be047176303e0e107539325f789ae4f 304 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 6 292 3.6E-56 T 29-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 SPSF3K_RS01590 9be047176303e0e107539325f789ae4f 304 Pfam PF11858 Domain of unknown function (DUF3378) 3 75 1.2E-20 T 29-03-2018 IPR024568 Ribonuclease HIII, N-terminal SPSF3K_RS00885 3bbcd5647c96941f0765faf059977266 121 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 1 118 2.0E-33 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 SPSF3K_RS00885 3bbcd5647c96941f0765faf059977266 121 Gene3D G3DSA:2.40.33.40 3 119 1.4E-38 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 SPSF3K_RS00885 3bbcd5647c96941f0765faf059977266 121 SUPERFAMILY SSF141530 4 119 8.5E-37 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 SPSF3K_RS00885 3bbcd5647c96941f0765faf059977266 121 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 5 117 4.7E-38 T 29-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 Gene3D G3DSA:3.30.1360.40 78 151 2.2E-11 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 Pfam PF02863 Arginine repressor, C-terminal domain 98 148 9.2E-8 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 Gene3D G3DSA:1.10.10.10 3 66 1.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 SUPERFAMILY SSF46785 1 69 5.92E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.3E-12 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.3E-12 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 PRINTS PR01467 Bacterial arginine repressor signature 121 136 2.3E-12 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 Hamap MF_00173 Arginine repressor [argR]. 1 155 42.475 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 Pfam PF01316 Arginine repressor, DNA binding domain 1 69 1.6E-21 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 SPSF3K_RS08805 b1c05dba0f3630f8431d2fb4ba6017d0 156 SUPERFAMILY SSF55252 94 151 2.62E-11 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 Gene3D G3DSA:3.90.700.10 748 908 4.3E-34 T 29-03-2018 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 15 333 1.8E-68 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 SUPERFAMILY SSF56425 760 910 3.66E-26 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 Pfam PF00890 FAD binding domain 505 947 4.6E-53 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 Gene3D G3DSA:3.20.20.70 1 370 3.4E-96 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 SMART SM00900 402 476 3.2E-11 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 SUPERFAMILY SSF51905 489 738 1.6E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 SUPERFAMILY SSF51905 909 966 1.6E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 Pfam PF04205 FMN-binding domain 402 472 1.7E-9 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 914 936 1.2E-7 T 29-03-2018 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 506 525 1.2E-7 T 29-03-2018 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 SUPERFAMILY SSF51395 3 337 2.75E-94 T 29-03-2018 SPSF3K_RS09315 d5ea032a96c582f22a527c4946fc41f1 968 Gene3D G3DSA:3.50.50.60 498 709 7.0E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS00145 ccb8591ed5946e533f635c6def35ee08 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00145 ccb8591ed5946e533f635c6def35ee08 150 SUPERFAMILY SSF55658 1 56 4.36E-15 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal SPSF3K_RS00145 ccb8591ed5946e533f635c6def35ee08 150 Gene3D G3DSA:3.10.430.100 63 149 5.2E-26 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal SPSF3K_RS00145 ccb8591ed5946e533f635c6def35ee08 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 1.8E-38 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00145 ccb8591ed5946e533f635c6def35ee08 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 23.442 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00145 ccb8591ed5946e533f635c6def35ee08 150 Gene3D G3DSA:3.40.5.10 1 49 1.3E-19 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00145 ccb8591ed5946e533f635c6def35ee08 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 3.1E-19 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00145 ccb8591ed5946e533f635c6def35ee08 150 SUPERFAMILY SSF55653 57 147 2.49E-25 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal SPSF3K_RS00145 ccb8591ed5946e533f635c6def35ee08 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 1.8E-26 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 Gene3D G3DSA:1.20.1250.20 2 190 2.8E-23 T 29-03-2018 SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 Gene3D G3DSA:1.20.1250.20 244 446 7.4E-20 T 29-03-2018 SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 Pfam PF07690 Major Facilitator Superfamily 16 395 3.8E-36 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 SUPERFAMILY SSF103473 1 200 1.57E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 SUPERFAMILY SSF103473 235 444 1.57E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 1.0E-11 T 29-03-2018 SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 PRINTS PR01036 Tetracycline resistance protein TetB signature 221 239 1.0E-11 T 29-03-2018 SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 1.0E-11 T 29-03-2018 SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 PRINTS PR01036 Tetracycline resistance protein TetB signature 288 312 1.0E-11 T 29-03-2018 SPSF3K_RS06295 47b3afcaa84f346b24a7d1f366cd14bc 447 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 1.0E-11 T 29-03-2018 SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 SUPERFAMILY SSF54814 2 105 1.31E-37 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 SMART SM00322 59 124 1.2E-8 T 29-03-2018 IPR004087 K Homology domain GO:0003676 SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 3.5E-92 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.877 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 Gene3D G3DSA:3.30.300.20 17 106 6.7E-30 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 2.3E-39 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 Pfam PF07650 KH domain 38 109 1.8E-20 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 Gene3D G3DSA:3.30.1140.32 107 206 1.0E-35 T 29-03-2018 SPSF3K_RS10490 79d30614ac5ce2be383cfb871c2ed64e 217 SUPERFAMILY SSF54821 106 205 1.83E-37 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10650 6340a387f1ed54e40382ead4c22daa33 392 Gene3D G3DSA:3.40.640.10 45 299 3.5E-56 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS10650 6340a387f1ed54e40382ead4c22daa33 392 SUPERFAMILY SSF53383 7 387 5.72E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS10650 6340a387f1ed54e40382ead4c22daa33 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 SPSF3K_RS10650 6340a387f1ed54e40382ead4c22daa33 392 Pfam PF00155 Aminotransferase class I and II 32 383 3.3E-61 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SPSF3K_RS10650 6340a387f1ed54e40382ead4c22daa33 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 115 136 6.3E-13 T 29-03-2018 SPSF3K_RS10650 6340a387f1ed54e40382ead4c22daa33 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 200 223 6.3E-13 T 29-03-2018 SPSF3K_RS10650 6340a387f1ed54e40382ead4c22daa33 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 93 113 6.3E-13 T 29-03-2018 SPSF3K_RS10650 6340a387f1ed54e40382ead4c22daa33 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 164 188 6.3E-13 T 29-03-2018 SPSF3K_RS10650 6340a387f1ed54e40382ead4c22daa33 392 Gene3D G3DSA:3.90.1150.10 300 391 1.2E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS04140 4b1b7ea9febba7d10d257ae50682450f 259 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS04140 4b1b7ea9febba7d10d257ae50682450f 259 SUPERFAMILY SSF52540 3 239 7.05E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04140 4b1b7ea9febba7d10d257ae50682450f 259 Pfam PF00005 ABC transporter 19 168 1.0E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS04140 4b1b7ea9febba7d10d257ae50682450f 259 PIRSF PIRSF039085 1 245 9.7E-102 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SPSF3K_RS04140 4b1b7ea9febba7d10d257ae50682450f 259 Gene3D G3DSA:3.40.50.300 1 258 4.5E-72 T 29-03-2018 SPSF3K_RS04140 4b1b7ea9febba7d10d257ae50682450f 259 SMART SM00382 28 216 1.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00305 673818dadefb5e284ac460f3a8c1f73e 425 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 409 5.4E-156 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SPSF3K_RS00305 673818dadefb5e284ac460f3a8c1f73e 425 Pfam PF13393 Histidyl-tRNA synthetase 8 312 7.8E-43 T 29-03-2018 SPSF3K_RS00305 673818dadefb5e284ac460f3a8c1f73e 425 SUPERFAMILY SSF52954 328 418 2.78E-22 T 29-03-2018 IPR004154 Anticodon-binding SPSF3K_RS00305 673818dadefb5e284ac460f3a8c1f73e 425 Gene3D G3DSA:3.30.930.10 1 322 1.2E-73 T 29-03-2018 SPSF3K_RS00305 673818dadefb5e284ac460f3a8c1f73e 425 SUPERFAMILY SSF55681 3 319 1.91E-99 T 29-03-2018 SPSF3K_RS00305 673818dadefb5e284ac460f3a8c1f73e 425 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 423 33.596 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 SPSF3K_RS00305 673818dadefb5e284ac460f3a8c1f73e 425 PIRSF PIRSF001549 1 419 1.2E-121 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 SPSF3K_RS00305 673818dadefb5e284ac460f3a8c1f73e 425 Gene3D G3DSA:3.40.50.800 326 425 1.9E-16 T 29-03-2018 IPR004154 Anticodon-binding SPSF3K_RS00305 673818dadefb5e284ac460f3a8c1f73e 425 Pfam PF03129 Anticodon binding domain 339 415 1.6E-11 T 29-03-2018 IPR004154 Anticodon-binding SPSF3K_RS02045 d6a89561aeff19f2e4d397ea7b81b9ce 213 SUPERFAMILY SSF52540 1 208 7.14E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02045 d6a89561aeff19f2e4d397ea7b81b9ce 213 Gene3D G3DSA:3.40.50.300 1 210 1.1E-44 T 29-03-2018 SPSF3K_RS02045 d6a89561aeff19f2e4d397ea7b81b9ce 213 PIRSF PIRSF000705 1 212 2.3E-56 T 29-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 SPSF3K_RS02045 d6a89561aeff19f2e4d397ea7b81b9ce 213 Pfam PF01712 Deoxynucleoside kinase 3 207 6.1E-58 T 29-03-2018 IPR031314 Deoxynucleoside kinase domain SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 SMART SM01130 7 296 6.5E-111 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 Gene3D G3DSA:3.20.20.70 5 300 2.3E-85 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 140 170 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 10 290 5.2E-88 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 4.2E-28 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 135 152 4.2E-28 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 4.2E-28 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 110 126 4.2E-28 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 Pfam PF00701 Dihydrodipicolinate synthetase family 10 289 4.2E-82 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 SUPERFAMILY SSF51569 11 290 8.16E-88 T 29-03-2018 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 PIRSF PIRSF001365 6 301 5.1E-82 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 SPSF3K_RS06945 9a214482668dd0b9250f1e87e4e49994 309 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 7 293 57.326 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS06600 ee8a34b97cfaafb1ebed0ef3c6c52a6c 113 Gene3D G3DSA:1.10.10.10 2 110 3.2E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06600 ee8a34b97cfaafb1ebed0ef3c6c52a6c 113 Hamap MF_00245 UPF0122 protein . 6 107 20.641 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like SPSF3K_RS06600 ee8a34b97cfaafb1ebed0ef3c6c52a6c 113 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 6 103 9.5E-42 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like SPSF3K_RS06600 ee8a34b97cfaafb1ebed0ef3c6c52a6c 113 SUPERFAMILY SSF88659 7 109 1.07E-32 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS06205 4066efa1bda824f1538ff99e74cac98c 204 SUPERFAMILY SSF53254 1 187 7.72E-46 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS06205 4066efa1bda824f1538ff99e74cac98c 204 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 SPSF3K_RS06205 4066efa1bda824f1538ff99e74cac98c 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 187 9.4E-40 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS06205 4066efa1bda824f1538ff99e74cac98c 204 SMART SM00855 4 153 1.7E-20 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS06205 4066efa1bda824f1538ff99e74cac98c 204 PIRSF PIRSF000709 1 150 2.8E-13 T 29-03-2018 SPSF3K_RS06205 4066efa1bda824f1538ff99e74cac98c 204 Gene3D G3DSA:3.40.50.1240 1 192 1.7E-41 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS01100 afcbefd98aa5116ff05d43998ef08ab8 296 Gene3D G3DSA:3.30.420.40 2 118 1.7E-20 T 29-03-2018 SPSF3K_RS01100 afcbefd98aa5116ff05d43998ef08ab8 296 SUPERFAMILY SSF53067 1 291 2.27E-54 T 29-03-2018 SPSF3K_RS01100 afcbefd98aa5116ff05d43998ef08ab8 296 Pfam PF00480 ROK family 4 291 2.9E-50 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SPSF3K_RS01100 afcbefd98aa5116ff05d43998ef08ab8 296 Gene3D G3DSA:3.30.420.40 119 293 4.4E-37 T 29-03-2018 SPSF3K_RS07110 69341f8cbe07eff977b2ded35783aa82 445 Pfam PF09903 Uncharacterized protein conserved in bacteria (DUF2130) 173 430 1.3E-88 T 29-03-2018 IPR019219 Protein of unknown function DUF2130 SPSF3K_RS07110 69341f8cbe07eff977b2ded35783aa82 445 PIRSF PIRSF005850 1 445 3.4E-150 T 29-03-2018 IPR019219 Protein of unknown function DUF2130 SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 Gene3D G3DSA:1.10.10.10 3 63 9.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 SMART SM00116 153 205 0.042 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 SMART SM00116 86 134 29.0 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 Gene3D G3DSA:3.10.580.10 64 210 1.7E-20 T 29-03-2018 SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 SUPERFAMILY SSF46785 7 78 1.17E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 Pfam PF00571 CBS domain 147 202 5.8E-5 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 Pfam PF00571 CBS domain 81 132 1.3E-4 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 PIRSF PIRSF026546 4 210 1.5E-84 T 29-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 SUPERFAMILY SSF54631 73 205 2.99E-19 T 29-03-2018 SPSF3K_RS10220 b25031f74e2368abbe606778e66c0576 210 Pfam PF08279 HTH domain 9 61 6.7E-11 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SPSF3K_RS04395 4e4e0ab7313402b8605e7e73cb63cea3 157 Gene3D G3DSA:3.90.960.10 1 157 2.9E-27 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS04395 4e4e0ab7313402b8605e7e73cb63cea3 157 SUPERFAMILY SSF55826 7 155 5.1E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS04395 4e4e0ab7313402b8605e7e73cb63cea3 157 Pfam PF04073 Aminoacyl-tRNA editing domain 38 147 8.7E-20 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS04395 4e4e0ab7313402b8605e7e73cb63cea3 157 PIRSF PIRSF006181 5 157 1.5E-47 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SPSF3K_RS10150 5796baa143b5f111d2672e65f77d0a2d 250 SUPERFAMILY SSF55166 84 233 4.19E-23 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SPSF3K_RS10150 5796baa143b5f111d2672e65f77d0a2d 250 Gene3D G3DSA:3.30.1380.10 53 238 8.7E-26 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SPSF3K_RS10150 5796baa143b5f111d2672e65f77d0a2d 250 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 91 226 2.8E-34 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 PIRSF PIRSF000097 1 278 3.6E-82 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 40 57 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 130 147 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 234 249 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 SUPERFAMILY SSF51430 1 267 1.22E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 Gene3D G3DSA:3.20.20.100 1 278 9.6E-97 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 PRINTS PR00069 Aldo-keto reductase signature 164 193 5.8E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 PRINTS PR00069 Aldo-keto reductase signature 201 225 5.8E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 PRINTS PR00069 Aldo-keto reductase signature 130 147 5.8E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 PRINTS PR00069 Aldo-keto reductase signature 92 110 5.8E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 PRINTS PR00069 Aldo-keto reductase signature 36 60 5.8E-48 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPSF3K_RS09890 7d53c38d07cb12325a8b72e10bbe36b9 279 Pfam PF00248 Aldo/keto reductase family 16 265 1.3E-50 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain SPSF3K_RS06805 7f2d9a429f2e2dabf7b225712242c2db 315 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 210 311 1.6E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS06805 7f2d9a429f2e2dabf7b225712242c2db 315 SUPERFAMILY SSF55874 156 311 2.62E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS06805 7f2d9a429f2e2dabf7b225712242c2db 315 Gene3D G3DSA:3.30.565.10 82 311 9.9E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS06805 7f2d9a429f2e2dabf7b225712242c2db 315 SMART SM00387 209 315 7.9E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS07015 f60b727ddfadb42910432e3563d4b5a6 220 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 215 37.512 T 29-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 SPSF3K_RS07015 f60b727ddfadb42910432e3563d4b5a6 220 SMART SM01133 2 213 6.2E-101 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SPSF3K_RS07015 f60b727ddfadb42910432e3563d4b5a6 220 SUPERFAMILY SSF51569 2 213 5.23E-85 T 29-03-2018 SPSF3K_RS07015 f60b727ddfadb42910432e3563d4b5a6 220 PIRSF PIRSF001357 1 219 3.9E-79 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SPSF3K_RS07015 f60b727ddfadb42910432e3563d4b5a6 220 Gene3D G3DSA:3.20.20.70 1 219 1.1E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS07015 f60b727ddfadb42910432e3563d4b5a6 220 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 211 2.2E-89 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SPSF3K_RS07015 f60b727ddfadb42910432e3563d4b5a6 220 Pfam PF01791 DeoC/LacD family aldolase 7 210 3.3E-20 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SPSF3K_RS07920 46110c36109912b8a636617dd34896fd 155 Pfam PF00583 Acetyltransferase (GNAT) family 38 117 7.1E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS07920 46110c36109912b8a636617dd34896fd 155 SUPERFAMILY SSF55729 18 150 1.88E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS07920 46110c36109912b8a636617dd34896fd 155 Gene3D G3DSA:3.40.630.30 13 154 1.1E-15 T 29-03-2018 SPSF3K_RS01295 557578868d5ead6e9bc075c10e8ce04d 198 Gene3D G3DSA:3.30.420.10 1 169 2.2E-26 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS01295 557578868d5ead6e9bc075c10e8ce04d 198 SMART SM00479 6 171 8.7E-17 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SPSF3K_RS01295 557578868d5ead6e9bc075c10e8ce04d 198 SUPERFAMILY SSF53098 6 171 7.28E-27 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS01295 557578868d5ead6e9bc075c10e8ce04d 198 Pfam PF00929 Exonuclease 8 162 9.4E-14 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III SPSF3K_RS09465 7208ed51b125311cb22eadf01732d5e1 212 Gene3D G3DSA:1.10.10.60 15 59 5.1E-16 T 29-03-2018 SPSF3K_RS09465 7208ed51b125311cb22eadf01732d5e1 212 Gene3D G3DSA:1.10.10.60 60 183 4.3E-9 T 29-03-2018 SPSF3K_RS09465 7208ed51b125311cb22eadf01732d5e1 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 4.3E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS09465 7208ed51b125311cb22eadf01732d5e1 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 7.8E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS09465 7208ed51b125311cb22eadf01732d5e1 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 7.8E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS09465 7208ed51b125311cb22eadf01732d5e1 212 SUPERFAMILY SSF46689 23 90 3.09E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS08100 ba24239a979147d56ac6a23a22d014fd 289 Gene3D G3DSA:3.90.550.10 1 289 4.8E-75 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS08100 ba24239a979147d56ac6a23a22d014fd 289 Pfam PF00483 Nucleotidyl transferase 2 237 1.3E-73 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 SPSF3K_RS08100 ba24239a979147d56ac6a23a22d014fd 289 SUPERFAMILY SSF53448 1 286 9.01E-93 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS08100 ba24239a979147d56ac6a23a22d014fd 289 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.5E-153 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 SPSF3K_RS04795 4f8cbedec41a91f0c4c45153c9dcf005 106 Gene3D G3DSA:3.40.50.10580 5 106 2.4E-23 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04795 4f8cbedec41a91f0c4c45153c9dcf005 106 Pfam PF01990 ATP synthase (F/14-kDa) subunit 8 97 1.0E-19 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04795 4f8cbedec41a91f0c4c45153c9dcf005 106 SUPERFAMILY SSF159468 8 105 1.96E-22 T 29-03-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS07025 7308fee58b5825546a191c02a3042268 199 Pfam PF05175 Methyltransferase small domain 28 192 2.9E-50 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SPSF3K_RS07025 7308fee58b5825546a191c02a3042268 199 Gene3D G3DSA:3.40.50.150 24 199 5.3E-27 T 29-03-2018 SPSF3K_RS07025 7308fee58b5825546a191c02a3042268 199 SUPERFAMILY SSF53335 8 194 7.25E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS07025 7308fee58b5825546a191c02a3042268 199 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 61 75 8.6E-5 T 29-03-2018 SPSF3K_RS07025 7308fee58b5825546a191c02a3042268 199 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 122 134 8.6E-5 T 29-03-2018 SPSF3K_RS07025 7308fee58b5825546a191c02a3042268 199 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 136 160 8.6E-5 T 29-03-2018 SPSF3K_RS01850 b2d8c7d92ab4bc0f08038747a6b36a1e 348 SUPERFAMILY SSF51735 150 310 3.63E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS01850 b2d8c7d92ab4bc0f08038747a6b36a1e 348 Gene3D G3DSA:3.90.180.10 1 156 9.1E-35 T 29-03-2018 SPSF3K_RS01850 b2d8c7d92ab4bc0f08038747a6b36a1e 348 Gene3D G3DSA:3.40.50.10730 157 310 5.5E-25 T 29-03-2018 SPSF3K_RS01850 b2d8c7d92ab4bc0f08038747a6b36a1e 348 SUPERFAMILY SSF50129 1 184 8.22E-44 T 29-03-2018 IPR011032 GroES-like SPSF3K_RS01850 b2d8c7d92ab4bc0f08038747a6b36a1e 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 125 4.4E-23 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SPSF3K_RS01850 b2d8c7d92ab4bc0f08038747a6b36a1e 348 Pfam PF00107 Zinc-binding dehydrogenase 181 285 6.4E-21 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SPSF3K_RS02165 deaef786cb9cc337bc69d192da74c7e3 390 Gene3D G3DSA:2.60.40.1240 27 175 1.4E-20 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain SPSF3K_RS02165 deaef786cb9cc337bc69d192da74c7e3 390 Pfam PF11611 Domain of unknown function (DUF4352) 31 145 1.4E-11 T 29-03-2018 IPR029051 Domain of unknown function DUF4352 SPSF3K_RS08530 c4fa984b82cbabfef138e777e607cd2b 475 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS08530 c4fa984b82cbabfef138e777e607cd2b 475 Gene3D G3DSA:3.40.309.10 266 455 9.8E-59 T 29-03-2018 SPSF3K_RS08530 c4fa984b82cbabfef138e777e607cd2b 475 Gene3D G3DSA:3.40.605.10 1 265 2.9E-82 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS08530 c4fa984b82cbabfef138e777e607cd2b 475 Pfam PF00171 Aldehyde dehydrogenase family 16 470 3.0E-149 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS08530 c4fa984b82cbabfef138e777e607cd2b 475 SUPERFAMILY SSF53720 3 473 1.57E-141 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS00935 a3dca6e3c5d45447aa91a0c775809d66 149 Pfam PF12802 MarR family 33 89 9.1E-12 T 29-03-2018 SPSF3K_RS00935 a3dca6e3c5d45447aa91a0c775809d66 149 SMART SM00347 21 126 1.3E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS00935 a3dca6e3c5d45447aa91a0c775809d66 149 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 99 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site SPSF3K_RS00935 a3dca6e3c5d45447aa91a0c775809d66 149 Gene3D G3DSA:1.10.10.10 1 126 2.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00935 a3dca6e3c5d45447aa91a0c775809d66 149 SUPERFAMILY SSF46785 7 136 4.36E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02555 b0b15df2913f98b616cc994d96456c3a 249 Gene3D G3DSA:3.40.1180.10 3 249 1.1E-91 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SPSF3K_RS02555 b0b15df2913f98b616cc994d96456c3a 249 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 16 247 7.1E-81 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SPSF3K_RS02555 b0b15df2913f98b616cc994d96456c3a 249 SUPERFAMILY SSF64005 12 243 8.37E-88 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SPSF3K_RS02555 b0b15df2913f98b616cc994d96456c3a 249 Pfam PF01255 Putative undecaprenyl diphosphate synthase 23 247 2.1E-79 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SPSF3K_RS02555 b0b15df2913f98b616cc994d96456c3a 249 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 16 248 40.126 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 SPSF3K_RS06865 58cb3dff6399009fb4605ba14b1a1247 279 SUPERFAMILY SSF102405 74 274 2.47E-33 T 29-03-2018 SPSF3K_RS06865 58cb3dff6399009fb4605ba14b1a1247 279 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 277 4.1E-74 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 SPSF3K_RS06865 58cb3dff6399009fb4605ba14b1a1247 279 Pfam PF02481 DNA recombination-mediator protein A 72 269 9.7E-76 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 SPSF3K_RS06865 58cb3dff6399009fb4605ba14b1a1247 279 Gene3D G3DSA:3.40.50.450 104 263 1.4E-35 T 29-03-2018 SPSF3K_RS10025 361318c07237b04e0df484cbd1953bcf 329 Gene3D G3DSA:3.40.50.510 1 144 7.1E-39 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPSF3K_RS10025 361318c07237b04e0df484cbd1953bcf 329 SUPERFAMILY SSF52728 168 327 1.7E-53 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPSF3K_RS10025 361318c07237b04e0df484cbd1953bcf 329 SUPERFAMILY SSF53062 2 137 7.85E-36 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPSF3K_RS10025 361318c07237b04e0df484cbd1953bcf 329 Pfam PF03830 PTS system sorbose subfamily IIB component 169 316 1.1E-50 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPSF3K_RS10025 361318c07237b04e0df484cbd1953bcf 329 Pfam PF03610 PTS system fructose IIA component 4 121 5.4E-35 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPSF3K_RS10025 361318c07237b04e0df484cbd1953bcf 329 Gene3D G3DSA:3.40.35.10 168 324 5.6E-55 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPSF3K_RS01455 ebba7d763e8676419627e8f179de7b44 510 SUPERFAMILY SSF100950 35 240 5.8E-74 T 29-03-2018 SPSF3K_RS01455 ebba7d763e8676419627e8f179de7b44 510 TIGRFAM TIGR01584 citF: citrate lyase, alpha subunit 30 510 1.8E-239 T 29-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 SPSF3K_RS01455 ebba7d763e8676419627e8f179de7b44 510 Pfam PF04223 Citrate lyase, alpha subunit (CitF) 45 510 2.1E-254 T 29-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 SPSF3K_RS01455 ebba7d763e8676419627e8f179de7b44 510 Gene3D G3DSA:3.40.1080.10 243 486 3.4E-34 T 29-03-2018 SPSF3K_RS01455 ebba7d763e8676419627e8f179de7b44 510 Gene3D G3DSA:3.40.1080.10 1 241 1.3E-53 T 29-03-2018 SPSF3K_RS01455 ebba7d763e8676419627e8f179de7b44 510 SUPERFAMILY SSF100950 244 509 8.03E-58 T 29-03-2018 SPSF3K_RS01455 ebba7d763e8676419627e8f179de7b44 510 PIRSF PIRSF009451 1 510 9.9E-260 T 29-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 SPSF3K_RS02275 b8dade14e68aa52575ce90fa51210246 344 PIRSF PIRSF016521 41 344 4.5E-38 T 29-03-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 SPSF3K_RS02275 b8dade14e68aa52575ce90fa51210246 344 Gene3D G3DSA:3.40.50.1820 57 341 3.8E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS02275 b8dade14e68aa52575ce90fa51210246 344 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 129 341 1.8E-31 T 29-03-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal SPSF3K_RS02275 b8dade14e68aa52575ce90fa51210246 344 SUPERFAMILY SSF53474 217 303 5.3E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS02275 b8dade14e68aa52575ce90fa51210246 344 SUPERFAMILY SSF53474 41 186 5.3E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS02470 6ffbdabfa39af03f64106cba8563d0da 345 Pfam PF05343 M42 glutamyl aminopeptidase 45 334 5.8E-88 T 29-03-2018 IPR008007 Peptidase M42 SPSF3K_RS02470 6ffbdabfa39af03f64106cba8563d0da 345 SUPERFAMILY SSF53187 171 340 2.28E-55 T 29-03-2018 SPSF3K_RS02470 6ffbdabfa39af03f64106cba8563d0da 345 SUPERFAMILY SSF53187 3 75 2.28E-55 T 29-03-2018 SPSF3K_RS02470 6ffbdabfa39af03f64106cba8563d0da 345 PIRSF PIRSF001123 1 343 3.8E-42 T 29-03-2018 IPR008007 Peptidase M42 SPSF3K_RS02470 6ffbdabfa39af03f64106cba8563d0da 345 Gene3D G3DSA:3.40.630.10 2 341 2.4E-44 T 29-03-2018 SPSF3K_RS02470 6ffbdabfa39af03f64106cba8563d0da 345 SUPERFAMILY SSF101821 70 183 1.98E-29 T 29-03-2018 SPSF3K_RS00940 089d377f0e6728cb326399df5239fb6e 569 SMART SM00382 353 539 4.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00940 089d377f0e6728cb326399df5239fb6e 569 Pfam PF00664 ABC transporter transmembrane region 16 282 7.5E-37 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS00940 089d377f0e6728cb326399df5239fb6e 569 Gene3D G3DSA:1.20.1560.10 1 312 1.1E-57 T 29-03-2018 SPSF3K_RS00940 089d377f0e6728cb326399df5239fb6e 569 SUPERFAMILY SSF90123 3 311 3.01E-59 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPSF3K_RS00940 089d377f0e6728cb326399df5239fb6e 569 Pfam PF00005 ABC transporter 344 493 1.9E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00940 089d377f0e6728cb326399df5239fb6e 569 Gene3D G3DSA:3.40.50.300 313 569 2.9E-69 T 29-03-2018 SPSF3K_RS00940 089d377f0e6728cb326399df5239fb6e 569 SUPERFAMILY SSF52540 321 563 1.2E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00940 089d377f0e6728cb326399df5239fb6e 569 ProSitePatterns PS00211 ABC transporters family signature. 465 479 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS10670 ae2719a16584ac0070d4a9e14312f4d8 273 PIRSF PIRSF038471 2 273 9.6E-38 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 SPSF3K_RS10670 ae2719a16584ac0070d4a9e14312f4d8 273 Pfam PF04085 rod shape-determining protein MreC 120 269 2.4E-30 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 SPSF3K_RS03150 ac5983e3523bb4f742368ff8f41a4d47 117 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 2.7E-35 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SPSF3K_RS03150 ac5983e3523bb4f742368ff8f41a4d47 117 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 25.099 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SPSF3K_RS03150 ac5983e3523bb4f742368ff8f41a4d47 117 SUPERFAMILY SSF81301 1 114 1.05E-38 T 29-03-2018 SPSF3K_RS03150 ac5983e3523bb4f742368ff8f41a4d47 117 Gene3D G3DSA:3.30.460.10 1 114 1.2E-35 T 29-03-2018 SPSF3K_RS03150 ac5983e3523bb4f742368ff8f41a4d47 117 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 5.4E-27 T 29-03-2018 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 Pfam PF03952 Enolase, N-terminal domain 4 134 3.3E-61 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 SUPERFAMILY SSF51604 139 433 4.67E-126 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 432 2.1E-206 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 PIRSF PIRSF001400 1 432 5.5E-191 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 Gene3D G3DSA:3.20.20.120 128 435 1.1E-102 T 29-03-2018 IPR029065 Enolase C-terminal domain-like SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 Hamap MF_00318 Enolase [eno]. 2 418 44.829 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 Gene3D G3DSA:3.30.390.10 3 127 3.7E-54 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 430 8.7E-129 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 ProSitePatterns PS00164 Enolase signature. 341 354 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 PRINTS PR00148 Enolase signature 37 51 2.4E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 PRINTS PR00148 Enolase signature 161 174 2.4E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 PRINTS PR00148 Enolase signature 318 329 2.4E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 PRINTS PR00148 Enolase signature 341 355 2.4E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 PRINTS PR00148 Enolase signature 107 123 2.4E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 PRINTS PR00148 Enolase signature 370 387 2.4E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 SUPERFAMILY SSF54826 3 138 6.19E-58 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 SMART SM01192 139 432 2.3E-211 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS04730 ffc55639f12023e297ae65d0b58778fb 435 SMART SM01193 4 134 3.9E-95 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPSF3K_RS06660 097544a366bf8fc4ad404aa095f3a703 283 Gene3D G3DSA:3.40.50.10490 88 281 1.3E-21 T 29-03-2018 SPSF3K_RS06660 097544a366bf8fc4ad404aa095f3a703 283 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 64 7.1E-11 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SPSF3K_RS06660 097544a366bf8fc4ad404aa095f3a703 283 SUPERFAMILY SSF53697 96 263 3.34E-21 T 29-03-2018 SPSF3K_RS06660 097544a366bf8fc4ad404aa095f3a703 283 SUPERFAMILY SSF46689 13 71 1.34E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS06660 097544a366bf8fc4ad404aa095f3a703 283 Gene3D G3DSA:1.10.10.10 1 71 2.6E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06660 097544a366bf8fc4ad404aa095f3a703 283 Pfam PF01380 SIS domain 128 250 2.2E-12 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS09010 133ecf91dca874ac88ca26ed8559b4da 312 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 300 1.0E-48 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPSF3K_RS09010 133ecf91dca874ac88ca26ed8559b4da 312 Gene3D G3DSA:1.10.3470.10 25 306 3.1E-34 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS06345 5d314a744f695508a5b835a9f2ea11e4 422 TIGRFAM TIGR03173 pbuX: xanthine permease 15 418 5.8E-148 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 SPSF3K_RS06345 5d314a744f695508a5b835a9f2ea11e4 422 Pfam PF00860 Permease family 11 381 2.4E-100 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPSF3K_RS06345 5d314a744f695508a5b835a9f2ea11e4 422 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 333 353 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SPSF3K_RS06345 5d314a744f695508a5b835a9f2ea11e4 422 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 10 416 7.2E-117 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SPSF3K_RS10615 1ba63c1e65a2e9ccd6a4d67ac027b672 339 Gene3D G3DSA:3.90.650.10 169 339 4.8E-56 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SPSF3K_RS10615 1ba63c1e65a2e9ccd6a4d67ac027b672 339 Pfam PF00586 AIR synthase related protein, N-terminal domain 61 161 1.9E-16 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SPSF3K_RS10615 1ba63c1e65a2e9ccd6a4d67ac027b672 339 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 4 339 45.518 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS10615 1ba63c1e65a2e9ccd6a4d67ac027b672 339 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 329 2.3E-134 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS10615 1ba63c1e65a2e9ccd6a4d67ac027b672 339 SUPERFAMILY SSF56042 169 337 2.24E-54 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SPSF3K_RS10615 1ba63c1e65a2e9ccd6a4d67ac027b672 339 SUPERFAMILY SSF55326 5 168 4.19E-48 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SPSF3K_RS10615 1ba63c1e65a2e9ccd6a4d67ac027b672 339 Pfam PF02769 AIR synthase related protein, C-terminal domain 175 338 4.1E-37 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain SPSF3K_RS10615 1ba63c1e65a2e9ccd6a4d67ac027b672 339 Gene3D G3DSA:3.30.1330.10 31 159 1.1E-54 T 29-03-2018 IPR016188 PurM-like, N-terminal domain SPSF3K_RS04335 4298ff428e7ce94d188d12a87bacd319 299 SMART SM01221 181 296 2.8E-75 T 29-03-2018 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04335 4298ff428e7ce94d188d12a87bacd319 299 Gene3D G3DSA:3.30.990.10 2 180 5.7E-67 T 29-03-2018 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 SPSF3K_RS04335 4298ff428e7ce94d188d12a87bacd319 299 SMART SM01222 3 180 3.0E-111 T 29-03-2018 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 SPSF3K_RS04335 4298ff428e7ce94d188d12a87bacd319 299 SUPERFAMILY SSF55116 3 180 4.71E-70 T 29-03-2018 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 SPSF3K_RS04335 4298ff428e7ce94d188d12a87bacd319 299 TIGRFAM TIGR02024 FtcD: glutamate formiminotransferase 1 297 1.2E-131 T 29-03-2018 IPR004227 Formiminotransferase catalytic domain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04335 4298ff428e7ce94d188d12a87bacd319 299 Pfam PF07837 Formiminotransferase domain, N-terminal subdomain 4 179 2.1E-72 T 29-03-2018 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 SPSF3K_RS04335 4298ff428e7ce94d188d12a87bacd319 299 Pfam PF02971 Formiminotransferase domain 182 285 1.4E-25 T 29-03-2018 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04335 4298ff428e7ce94d188d12a87bacd319 299 Gene3D G3DSA:3.30.70.670 182 298 4.0E-38 T 29-03-2018 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04335 4298ff428e7ce94d188d12a87bacd319 299 SUPERFAMILY SSF55116 181 292 8.37E-45 T 29-03-2018 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 SPSF3K_RS06340 d0a3c5e763c0f6969df890d2da04db5f 193 Pfam PF00156 Phosphoribosyl transferase domain 36 181 2.9E-8 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPSF3K_RS06340 d0a3c5e763c0f6969df890d2da04db5f 193 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 189 1.6E-79 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 SPSF3K_RS06340 d0a3c5e763c0f6969df890d2da04db5f 193 SUPERFAMILY SSF53271 1 187 5.54E-47 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS06340 d0a3c5e763c0f6969df890d2da04db5f 193 Gene3D G3DSA:3.40.50.2020 3 188 9.8E-25 T 29-03-2018 SPSF3K_RS06340 d0a3c5e763c0f6969df890d2da04db5f 193 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 40.925 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 SPSF3K_RS05435 4687326e03bb6399e21bbfa312c0d086 279 Pfam PF00303 Thymidylate synthase 8 279 4.3E-62 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SPSF3K_RS05435 4687326e03bb6399e21bbfa312c0d086 279 SUPERFAMILY SSF55831 3 278 1.15E-71 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SPSF3K_RS05435 4687326e03bb6399e21bbfa312c0d086 279 PRINTS PR00108 Thymidylate synthase family signature 209 226 6.5E-14 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SPSF3K_RS05435 4687326e03bb6399e21bbfa312c0d086 279 PRINTS PR00108 Thymidylate synthase family signature 171 197 6.5E-14 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SPSF3K_RS05435 4687326e03bb6399e21bbfa312c0d086 279 PRINTS PR00108 Thymidylate synthase family signature 54 75 6.5E-14 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SPSF3K_RS05435 4687326e03bb6399e21bbfa312c0d086 279 PRINTS PR00108 Thymidylate synthase family signature 122 141 6.5E-14 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SPSF3K_RS05435 4687326e03bb6399e21bbfa312c0d086 279 Hamap MF_00008 Thymidylate synthase [thyA]. 5 279 33.661 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SPSF3K_RS05435 4687326e03bb6399e21bbfa312c0d086 279 ProSitePatterns PS00091 Thymidylate synthase active site. 133 162 - T 29-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SPSF3K_RS05435 4687326e03bb6399e21bbfa312c0d086 279 Gene3D G3DSA:3.30.572.10 5 279 2.6E-61 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 SPSF3K_RS02675 050d5d3a65cfadf32c80aa6b0d954744 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 280 3.6E-83 T 29-03-2018 IPR003797 DegV SPSF3K_RS02675 050d5d3a65cfadf32c80aa6b0d954744 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 9.2E-78 T 29-03-2018 IPR003797 DegV SPSF3K_RS02675 050d5d3a65cfadf32c80aa6b0d954744 286 Gene3D G3DSA:3.30.1180.10 158 286 1.9E-34 T 29-03-2018 SPSF3K_RS02675 050d5d3a65cfadf32c80aa6b0d954744 286 Gene3D G3DSA:3.40.50.10170 1 157 1.2E-39 T 29-03-2018 SPSF3K_RS02675 050d5d3a65cfadf32c80aa6b0d954744 286 SUPERFAMILY SSF82549 1 281 8.11E-77 T 29-03-2018 SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 Gene3D G3DSA:3.90.226.10 1 194 5.9E-42 T 29-03-2018 SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 193 39.359 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 Pfam PF00574 Clp protease 10 192 1.2E-76 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 88 105 3.9E-43 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.9E-43 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 17 32 3.9E-43 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 57 77 3.9E-43 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 109 128 3.9E-43 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 SUPERFAMILY SSF52096 8 193 4.59E-66 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 110 123 - T 29-03-2018 IPR033135 ClpP, histidine active site SPSF3K_RS03590 54f39ca6e20183b79e176a16826c353e 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 88 99 - T 29-03-2018 IPR018215 ClpP, Ser active site SPSF3K_RS08145 18fa2a5e5f3382f525521847228b4c39 735 SUPERFAMILY SSF64182 58 435 8.24E-114 T 29-03-2018 SPSF3K_RS08145 18fa2a5e5f3382f525521847228b4c39 735 Gene3D G3DSA:3.90.1640.10 64 247 6.4E-27 T 29-03-2018 SPSF3K_RS08145 18fa2a5e5f3382f525521847228b4c39 735 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 578 727 7.7E-34 T 29-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal SPSF3K_RS08145 18fa2a5e5f3382f525521847228b4c39 735 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 32 556 3.6E-175 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 SPSF3K_RS08145 18fa2a5e5f3382f525521847228b4c39 735 Pfam PF01368 DHH family 84 228 2.3E-11 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SPSF3K_RS08145 18fa2a5e5f3382f525521847228b4c39 735 Pfam PF02272 DHHA1 domain 317 433 7.9E-18 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 SPSF3K_RS01240 b5885f4cbedb3052c4e8e4a1e49ac4e9 343 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 85 1.4E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SPSF3K_RS01240 b5885f4cbedb3052c4e8e4a1e49ac4e9 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 158 339 9.1E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01240 b5885f4cbedb3052c4e8e4a1e49ac4e9 343 Gene3D G3DSA:1.10.3720.10 29 330 8.3E-41 T 29-03-2018 SPSF3K_RS01240 b5885f4cbedb3052c4e8e4a1e49ac4e9 343 SUPERFAMILY SSF161098 135 322 1.57E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS03600 c8fcda9cdbbcd4a2d70dfdcaaeb6af21 91 Hamap MF_01126 UPF0298 protein . 3 80 21.105 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 SPSF3K_RS03600 c8fcda9cdbbcd4a2d70dfdcaaeb6af21 91 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 7 76 8.2E-26 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 SPSF3K_RS03600 c8fcda9cdbbcd4a2d70dfdcaaeb6af21 91 PIRSF PIRSF031653 1 90 1.5E-29 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 SPSF3K_RS02895 3927838b839a493fb18bde14a55a5a79 187 Hamap MF_00800 UPF0340 protein . 1 187 91.637 T 29-03-2018 IPR006340 Protein of unknown function DUF436 SPSF3K_RS02895 3927838b839a493fb18bde14a55a5a79 187 SUPERFAMILY SSF110710 4 186 2.38E-75 T 29-03-2018 SPSF3K_RS02895 3927838b839a493fb18bde14a55a5a79 187 PIRSF PIRSF007510 1 182 2.5E-84 T 29-03-2018 IPR006340 Protein of unknown function DUF436 SPSF3K_RS02895 3927838b839a493fb18bde14a55a5a79 187 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 16 186 2.0E-65 T 29-03-2018 IPR006340 Protein of unknown function DUF436 SPSF3K_RS02895 3927838b839a493fb18bde14a55a5a79 187 Gene3D G3DSA:3.40.50.10360 5 181 1.6E-72 T 29-03-2018 IPR006340 Protein of unknown function DUF436 SPSF3K_RS02895 3927838b839a493fb18bde14a55a5a79 187 Pfam PF04260 Protein of unknown function (DUF436) 10 179 2.9E-68 T 29-03-2018 IPR006340 Protein of unknown function DUF436 SPSF3K_RS02895 3927838b839a493fb18bde14a55a5a79 187 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 9 179 6.6E-76 T 29-03-2018 IPR006340 Protein of unknown function DUF436 SPSF3K_RS04045 de440dead952cfa282fbf8be37e054f4 362 SUPERFAMILY SSF51445 1 240 4.69E-75 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS04045 de440dead952cfa282fbf8be37e054f4 362 SUPERFAMILY SSF50891 247 360 1.29E-31 T 29-03-2018 IPR029000 Cyclophilin-like domain SPSF3K_RS04045 de440dead952cfa282fbf8be37e054f4 362 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 360 6.3E-118 T 29-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic SPSF3K_RS04045 de440dead952cfa282fbf8be37e054f4 362 Gene3D G3DSA:2.40.100.10 247 359 9.6E-36 T 29-03-2018 IPR029000 Cyclophilin-like domain SPSF3K_RS04045 de440dead952cfa282fbf8be37e054f4 362 Gene3D G3DSA:3.20.20.70 3 238 5.6E-77 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS01420 b50113875e2dc057807051c0f862510d 231 SMART SM00895 92 216 4.0E-5 T 29-03-2018 IPR011711 GntR, C-terminal SPSF3K_RS01420 b50113875e2dc057807051c0f862510d 231 SMART SM00345 24 82 7.5E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS01420 b50113875e2dc057807051c0f862510d 231 Pfam PF07729 FCD domain 92 215 2.0E-16 T 29-03-2018 IPR011711 GntR, C-terminal SPSF3K_RS01420 b50113875e2dc057807051c0f862510d 231 Gene3D G3DSA:1.10.10.10 9 84 5.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01420 b50113875e2dc057807051c0f862510d 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 82 5.5E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS01420 b50113875e2dc057807051c0f862510d 231 SUPERFAMILY SSF46785 14 86 1.15E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01420 b50113875e2dc057807051c0f862510d 231 Gene3D G3DSA:1.20.120.530 85 227 3.1E-16 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SPSF3K_RS01420 b50113875e2dc057807051c0f862510d 231 SUPERFAMILY SSF48008 88 223 4.18E-17 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SPSF3K_RS04170 74d1e05edd6fc5fa429b9109a4e65319 268 SUPERFAMILY SSF56784 1 265 5.63E-57 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04170 74d1e05edd6fc5fa429b9109a4e65319 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 261 6.1E-42 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS04170 74d1e05edd6fc5fa429b9109a4e65319 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 261 2.5E-56 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04170 74d1e05edd6fc5fa429b9109a4e65319 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 233 7.9E-27 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS04170 74d1e05edd6fc5fa429b9109a4e65319 268 Gene3D G3DSA:3.40.50.1000 1 267 1.3E-28 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08995 12cf5ddea8e5b66a7e4285dd4dcb65b2 262 Pfam PF06265 Protein of unknown function (DUF1027) 30 111 1.4E-33 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 SPSF3K_RS08995 12cf5ddea8e5b66a7e4285dd4dcb65b2 262 PIRSF PIRSF012565 1 198 2.1E-65 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 SPSF3K_RS08995 12cf5ddea8e5b66a7e4285dd4dcb65b2 262 PIRSF PIRSF012565 176 262 0.45 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 SPSF3K_RS01710 efed2c06ba3640c89c98d029519fca50 471 Gene3D G3DSA:3.20.20.80 4 462 6.7E-126 T 29-03-2018 SPSF3K_RS01710 efed2c06ba3640c89c98d029519fca50 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 362 370 2.2E-11 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01710 efed2c06ba3640c89c98d029519fca50 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 431 443 2.2E-11 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01710 efed2c06ba3640c89c98d029519fca50 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 289 303 2.2E-11 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01710 efed2c06ba3640c89c98d029519fca50 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 424 2.2E-11 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01710 efed2c06ba3640c89c98d029519fca50 471 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 397 2.2E-11 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01710 efed2c06ba3640c89c98d029519fca50 471 Pfam PF00232 Glycosyl hydrolase family 1 5 459 2.4E-108 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS01710 efed2c06ba3640c89c98d029519fca50 471 SUPERFAMILY SSF51445 2 457 1.83E-139 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS04040 46b32e83144147dd5dd7d905e0335842 445 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 14 435 6.2E-93 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS04040 46b32e83144147dd5dd7d905e0335842 445 Pfam PF02378 Phosphotransferase system, EIIC 30 361 8.4E-44 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS04040 46b32e83144147dd5dd7d905e0335842 445 PIRSF PIRSF006351 1 443 4.1E-122 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS00210 73af2589a630ef12b9c96f3a9e913505 103 SUPERFAMILY SSF46785 7 91 3.76E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00210 73af2589a630ef12b9c96f3a9e913505 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 2.6E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00210 73af2589a630ef12b9c96f3a9e913505 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.6E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00210 73af2589a630ef12b9c96f3a9e913505 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 41 2.6E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00210 73af2589a630ef12b9c96f3a9e913505 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 2.6E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00210 73af2589a630ef12b9c96f3a9e913505 103 SMART SM00418 9 90 2.7E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00210 73af2589a630ef12b9c96f3a9e913505 103 Pfam PF01022 Bacterial regulatory protein, arsR family 16 62 2.7E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS00210 73af2589a630ef12b9c96f3a9e913505 103 Gene3D G3DSA:1.10.10.10 2 97 1.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00150 2b0d7c0fa61ddc0c3b519b1a54c4614e 452 Pfam PF03796 DnaB-like helicase C terminal domain 185 444 5.0E-111 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 SPSF3K_RS00150 2b0d7c0fa61ddc0c3b519b1a54c4614e 452 SUPERFAMILY SSF48024 8 119 1.14E-34 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SPSF3K_RS00150 2b0d7c0fa61ddc0c3b519b1a54c4614e 452 Gene3D G3DSA:3.40.50.300 167 451 5.4E-70 T 29-03-2018 SPSF3K_RS00150 2b0d7c0fa61ddc0c3b519b1a54c4614e 452 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 447 2.0E-168 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 SPSF3K_RS00150 2b0d7c0fa61ddc0c3b519b1a54c4614e 452 Pfam PF00772 DnaB-like helicase N terminal domain 10 110 7.6E-32 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SPSF3K_RS00150 2b0d7c0fa61ddc0c3b519b1a54c4614e 452 SUPERFAMILY SSF52540 183 438 4.15E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00150 2b0d7c0fa61ddc0c3b519b1a54c4614e 452 Gene3D G3DSA:1.10.860.10 3 151 1.3E-41 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 63 312 2.0E-28 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 1.7E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 6 16 1.7E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 Gene3D G3DSA:3.40.50.2300 173 305 2.2E-31 T 29-03-2018 SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 SUPERFAMILY SSF53822 61 317 1.26E-60 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 7.7E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 SUPERFAMILY SSF47413 4 62 4.41E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 Gene3D G3DSA:1.10.260.40 5 57 5.7E-21 T 29-03-2018 SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 Gene3D G3DSA:3.40.50.2300 58 172 1.7E-33 T 29-03-2018 SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 SMART SM00354 4 74 5.4E-30 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01485 ca5c125253f58145a77103d195cb5e27 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 29-03-2018 SPSF3K_RS06620 cc9bb39bce96092dd8815e426d29e500 474 SUPERFAMILY SSF100879 303 399 3.53E-9 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SPSF3K_RS06620 cc9bb39bce96092dd8815e426d29e500 474 Gene3D G3DSA:1.10.150.20 221 302 6.1E-16 T 29-03-2018 SPSF3K_RS06620 cc9bb39bce96092dd8815e426d29e500 474 Pfam PF00817 impB/mucB/samB family 103 207 4.1E-12 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SPSF3K_RS06620 cc9bb39bce96092dd8815e426d29e500 474 Gene3D G3DSA:3.30.70.270 109 218 1.9E-16 T 29-03-2018 SPSF3K_RS06620 cc9bb39bce96092dd8815e426d29e500 474 Gene3D G3DSA:3.30.1490.100 303 414 3.4E-19 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SPSF3K_RS06620 cc9bb39bce96092dd8815e426d29e500 474 SUPERFAMILY SSF56672 116 291 6.4E-48 T 29-03-2018 SPSF3K_RS06620 cc9bb39bce96092dd8815e426d29e500 474 SUPERFAMILY SSF56672 4 83 6.4E-48 T 29-03-2018 SPSF3K_RS06620 cc9bb39bce96092dd8815e426d29e500 474 Pfam PF11799 impB/mucB/samB family C-terminal domain 295 404 8.1E-16 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 SPSF3K_RS06620 cc9bb39bce96092dd8815e426d29e500 474 Pfam PF11798 IMS family HHH motif 223 255 1.0E-5 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 SPSF3K_RS01655 1384226908c34ad3e6a0ea96ecdd106a 358 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 288 300 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site SPSF3K_RS01655 1384226908c34ad3e6a0ea96ecdd106a 358 Pfam PF00557 Metallopeptidase family M24 140 341 4.2E-60 T 29-03-2018 IPR000994 Peptidase M24 SPSF3K_RS01655 1384226908c34ad3e6a0ea96ecdd106a 358 SUPERFAMILY SSF55920 99 352 2.75E-74 T 29-03-2018 IPR000994 Peptidase M24 SPSF3K_RS01655 1384226908c34ad3e6a0ea96ecdd106a 358 SUPERFAMILY SSF53092 7 130 7.67E-25 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal SPSF3K_RS01655 1384226908c34ad3e6a0ea96ecdd106a 358 Gene3D G3DSA:3.90.230.10 115 358 2.4E-76 T 29-03-2018 SPSF3K_RS01655 1384226908c34ad3e6a0ea96ecdd106a 358 Gene3D G3DSA:3.40.350.10 2 114 3.1E-25 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SPSF3K_RS01655 1384226908c34ad3e6a0ea96ecdd106a 358 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 131 4.5E-23 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 SPSF3K_RS02780 654f8ddb071020462607cc712df90761 197 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 83 184 4.5E-6 T 29-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger SPSF3K_RS04710 053c20fb768d31ab40f41610c0dccaea 215 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 6 210 4.9E-74 T 29-03-2018 SPSF3K_RS04710 053c20fb768d31ab40f41610c0dccaea 215 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 175 3.8E-24 T 29-03-2018 SPSF3K_RS04710 053c20fb768d31ab40f41610c0dccaea 215 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 7 178 2.9E-32 T 29-03-2018 SPSF3K_RS04710 053c20fb768d31ab40f41610c0dccaea 215 Gene3D G3DSA:3.40.50.1000 65 210 5.7E-26 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04710 053c20fb768d31ab40f41610c0dccaea 215 Gene3D G3DSA:1.10.150.210 18 64 9.9E-23 T 29-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 SPSF3K_RS04710 053c20fb768d31ab40f41610c0dccaea 215 SUPERFAMILY SSF56784 7 212 2.4E-49 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS03695 1e08d53153c6266e2b6e8afee5e68b12 300 Gene3D G3DSA:1.20.1510.10 6 218 5.3E-11 T 29-03-2018 SPSF3K_RS03695 1e08d53153c6266e2b6e8afee5e68b12 300 SUPERFAMILY SSF161111 5 216 1.96E-15 T 29-03-2018 SPSF3K_RS03695 1e08d53153c6266e2b6e8afee5e68b12 300 Pfam PF01545 Cation efflux family 12 216 1.0E-26 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 Gene3D G3DSA:3.40.190.10 34 154 6.0E-26 T 29-03-2018 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 Gene3D G3DSA:3.40.190.10 155 307 9.9E-35 T 29-03-2018 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 131 147 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 41 57 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 100 113 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 57 78 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 84 98 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 211 230 1.9E-58 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 SUPERFAMILY SSF53850 36 353 1.21E-87 T 29-03-2018 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 Pfam PF13416 Bacterial extracellular solute-binding protein 51 321 3.0E-33 T 29-03-2018 SPSF3K_RS06135 04acec6a1cf20bb47b22609812121a8d 357 PIRSF PIRSF019574 1 356 3.8E-124 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPSF3K_RS07065 c427801c5dc2b51d34b566c2cda52d59 267 Gene3D G3DSA:3.40.50.300 8 265 8.3E-56 T 29-03-2018 SPSF3K_RS07065 c427801c5dc2b51d34b566c2cda52d59 267 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 21 267 4.0E-120 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 SPSF3K_RS07065 c427801c5dc2b51d34b566c2cda52d59 267 SUPERFAMILY SSF52540 16 254 2.11E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07065 c427801c5dc2b51d34b566c2cda52d59 267 SMART SM00382 45 256 3.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS07065 c427801c5dc2b51d34b566c2cda52d59 267 Pfam PF00005 ABC transporter 37 191 2.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS07065 c427801c5dc2b51d34b566c2cda52d59 267 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 125 764 3.8E-172 T 29-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 SUPERFAMILY SSF51998 118 276 8.24E-140 T 29-03-2018 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 SUPERFAMILY SSF51998 348 367 8.24E-140 T 29-03-2018 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 SUPERFAMILY SSF51998 626 774 8.24E-140 T 29-03-2018 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 SUPERFAMILY SSF51998 425 581 8.24E-140 T 29-03-2018 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 Gene3D G3DSA:3.20.70.20 11 761 6.3E-166 T 29-03-2018 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 Pfam PF02867 Ribonucleotide reductase, barrel domain 179 754 8.1E-126 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 PRINTS PR01183 Ribonucleotide reductase large chain signature 495 518 2.5E-37 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 PRINTS PR01183 Ribonucleotide reductase large chain signature 561 584 2.5E-37 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 PRINTS PR01183 Ribonucleotide reductase large chain signature 533 555 2.5E-37 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 PRINTS PR01183 Ribonucleotide reductase large chain signature 626 653 2.5E-37 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 PRINTS PR01183 Ribonucleotide reductase large chain signature 254 273 2.5E-37 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS05735 3acc31299c0430ebe048298fd2fb67a8 827 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 124 172 2.5E-6 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS05995 735f955bf6673cf96fe1e3c53326dcb9 559 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 426 553 3.1E-33 T 29-03-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 SPSF3K_RS05995 735f955bf6673cf96fe1e3c53326dcb9 559 SUPERFAMILY SSF52794 458 543 5.75E-13 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS05995 735f955bf6673cf96fe1e3c53326dcb9 559 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 459 530 4.3E-10 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS05995 735f955bf6673cf96fe1e3c53326dcb9 559 Pfam PF02378 Phosphotransferase system, EIIC 28 347 2.7E-54 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS05995 735f955bf6673cf96fe1e3c53326dcb9 559 Gene3D G3DSA:3.40.50.2300 452 559 1.3E-15 T 29-03-2018 SPSF3K_RS08825 7befb6e693d7a460f6fc9b212278273c 442 Gene3D G3DSA:2.40.50.140 9 102 1.0E-7 T 29-03-2018 SPSF3K_RS08825 7befb6e693d7a460f6fc9b212278273c 442 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 2 439 27.687 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SPSF3K_RS08825 7befb6e693d7a460f6fc9b212278273c 442 Pfam PF13742 OB-fold nucleic acid binding domain 5 97 8.5E-24 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 SPSF3K_RS08825 7befb6e693d7a460f6fc9b212278273c 442 Pfam PF02601 Exonuclease VII, large subunit 123 436 1.1E-93 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 SPSF3K_RS08825 7befb6e693d7a460f6fc9b212278273c 442 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 6 349 5.6E-123 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 Hamap MF_00900 GTPase HflX [hflX]. 28 384 42.816 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 PIRSF PIRSF006809 1 409 3.8E-139 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 353 2.8E-133 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 Pfam PF13167 GTP-binding GTPase N-terminal 27 113 2.7E-33 T 29-03-2018 IPR025121 GTPase HflX, N-terminal SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 201 221 9.9E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 286 9.9E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 Gene3D G3DSA:3.40.50.300 158 406 2.0E-25 T 29-03-2018 SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 Pfam PF01926 50S ribosome-binding GTPase 200 319 1.3E-17 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 SUPERFAMILY SSF52540 199 359 2.97E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08165 7062b59f5b8910077bdc17b27518084c 412 Pfam PF16360 GTP-binding GTPase Middle Region 115 193 2.5E-29 T 29-03-2018 IPR032305 GTP-binding protein, middle domain SPSF3K_RS09765 e5b7f71a6cf283538eadcb03fbaead03 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 56 251 1.4E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS09765 e5b7f71a6cf283538eadcb03fbaead03 267 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 35 145 6.2E-16 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPSF3K_RS09765 e5b7f71a6cf283538eadcb03fbaead03 267 SUPERFAMILY SSF161098 37 236 9.29E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS09765 e5b7f71a6cf283538eadcb03fbaead03 267 Gene3D G3DSA:1.10.3720.10 4 254 1.3E-33 T 29-03-2018 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 521 651 1.2E-8 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 SUPERFAMILY SSF63520 302 396 1.83E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Pfam PF05043 Mga helix-turn-helix domain 93 169 1.5E-13 T 29-03-2018 IPR007737 Mga helix-turn-helix domain SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Gene3D G3DSA:1.10.10.10 89 156 1.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Gene3D G3DSA:3.40.930.10 511 655 7.7E-13 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 SUPERFAMILY SSF52794 402 487 9.42E-10 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Gene3D G3DSA:3.40.50.2300 400 489 5.0E-19 T 29-03-2018 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Gene3D G3DSA:1.10.10.10 1 69 3.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 SUPERFAMILY SSF63520 206 285 4.84E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Pfam PF08279 HTH domain 6 65 3.9E-12 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Pfam PF00874 PRD domain 209 282 3.9E-12 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Pfam PF00874 PRD domain 307 392 7.2E-19 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 404 482 7.5E-5 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 SUPERFAMILY SSF55804 513 652 1.92E-13 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Gene3D G3DSA:1.10.1790.10 283 397 4.7E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS04025 fdc8bba09138a5dbd95a7ce66fe64520 655 Gene3D G3DSA:1.10.1790.10 167 282 7.3E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS05945 a8bcf51d461954a73948a49be7e1f4db 464 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 8 96 3.7E-18 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS05945 a8bcf51d461954a73948a49be7e1f4db 464 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 6 89 2.3E-34 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 SPSF3K_RS05945 a8bcf51d461954a73948a49be7e1f4db 464 SUPERFAMILY SSF52794 4 103 1.22E-37 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS05945 a8bcf51d461954a73948a49be7e1f4db 464 Gene3D G3DSA:3.40.50.2300 4 100 7.9E-40 T 29-03-2018 SPSF3K_RS05945 a8bcf51d461954a73948a49be7e1f4db 464 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 120 455 1.9E-105 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 89 1.3E-15 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 256 24.95 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 212 234 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 SUPERFAMILY SSF48179 151 255 3.57E-31 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 256 7.1E-79 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 SUPERFAMILY SSF51735 1 152 1.03E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 PIRSF PIRSF000193 1 256 2.3E-70 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 Gene3D G3DSA:1.10.3730.10 150 256 9.2E-37 T 29-03-2018 SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 152 256 1.1E-36 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 SPSF3K_RS01995 0cbf65e06ae58d9287f4c6e0b36b65dc 256 Gene3D G3DSA:3.40.50.720 2 149 3.2E-23 T 29-03-2018 SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 Gene3D G3DSA:2.30.30.100 263 309 4.2E-12 T 29-03-2018 SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 Pfam PF03099 Biotin/lipoate A/B protein ligase family 111 207 3.6E-11 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 Gene3D G3DSA:1.10.10.10 2 54 1.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 Gene3D G3DSA:3.30.930.10 55 250 4.3E-37 T 29-03-2018 SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 84 308 1.0E-37 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 6 309 27.336 T 29-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 SUPERFAMILY SSF50037 263 308 4.12E-6 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 Pfam PF08279 HTH domain 5 57 2.7E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 SUPERFAMILY SSF55681 71 247 8.52E-41 T 29-03-2018 SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 SUPERFAMILY SSF46785 6 58 8.19E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08490 ab417b2367cfb872b4ab831facf3dc5b 313 Pfam PF02237 Biotin protein ligase C terminal domain 263 309 4.2E-11 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 SPSF3K_RS00920 b9a008348501a68bd67129061be4f82a 224 SUPERFAMILY SSF144091 7 189 1.12E-36 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SPSF3K_RS00920 b9a008348501a68bd67129061be4f82a 224 Gene3D G3DSA:1.20.1540.10 5 191 4.6E-37 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SPSF3K_RS00920 b9a008348501a68bd67129061be4f82a 224 Pfam PF01694 Rhomboid family 54 190 3.0E-29 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SPSF3K_RS08380 359e367f411392e8e62a4e0a94d6b015 252 Pfam PF00005 ABC transporter 22 173 7.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08380 359e367f411392e8e62a4e0a94d6b015 252 SMART SM00382 31 219 1.9E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08380 359e367f411392e8e62a4e0a94d6b015 252 SUPERFAMILY SSF52540 2 225 1.69E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08380 359e367f411392e8e62a4e0a94d6b015 252 Gene3D G3DSA:3.40.50.300 1 247 9.4E-61 T 29-03-2018 SPSF3K_RS08380 359e367f411392e8e62a4e0a94d6b015 252 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 Gene3D G3DSA:3.90.190.20 332 483 3.2E-29 T 29-03-2018 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 34 477 1.1E-92 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 SUPERFAMILY SSF53244 328 480 2.62E-31 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 Gene3D G3DSA:3.40.1190.10 107 331 9.8E-42 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 SUPERFAMILY SSF63418 16 107 4.32E-15 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 Pfam PF02875 Mur ligase family, glutamate ligase domain 328 413 1.4E-13 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 Pfam PF08245 Mur ligase middle domain 117 308 1.6E-33 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 2 481 27.676 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 SUPERFAMILY SSF53623 78 339 1.7E-47 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS03575 1842185074feecdf07dc630655135320 483 Gene3D G3DSA:3.40.1390.10 13 106 1.3E-13 T 29-03-2018 SPSF3K_RS10410 afbaf50b4547b2a94fdd5680c3a075d5 72 Gene3D G3DSA:2.40.50.140 1 72 3.4E-37 T 29-03-2018 SPSF3K_RS10410 afbaf50b4547b2a94fdd5680c3a075d5 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 5.1E-28 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 SPSF3K_RS10410 afbaf50b4547b2a94fdd5680c3a075d5 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.723 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SPSF3K_RS10410 afbaf50b4547b2a94fdd5680c3a075d5 72 SMART SM00316 4 72 2.2E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 SPSF3K_RS10410 afbaf50b4547b2a94fdd5680c3a075d5 72 SUPERFAMILY SSF50249 2 71 4.63E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS10410 afbaf50b4547b2a94fdd5680c3a075d5 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 3.4E-38 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SPSF3K_RS05875 2b239c6003015bdf1c02b020288867a5 31 ProDom PD018707 LEADER PEPTIDE METHYLASE PLASMID RESISTANCE RRNA METHYLTRANSFERASE ERMB 23S ANTIBIOTIC 1 31 9.0E-11 T 29-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 SPSF3K_RS05875 2b239c6003015bdf1c02b020288867a5 31 Pfam PF06308 23S rRNA methylase leader peptide (ErmC) 1 31 7.9E-25 T 29-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 SPSF3K_RS10140 ab8bf1f94392e68bd3feea700f26b1c5 346 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 2 56 1.6E-7 T 29-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 SPSF3K_RS10140 ab8bf1f94392e68bd3feea700f26b1c5 346 PIRSF PIRSF005485 1 333 7.6E-71 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SPSF3K_RS10140 ab8bf1f94392e68bd3feea700f26b1c5 346 Gene3D G3DSA:3.30.450.40 190 335 1.0E-12 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS10140 ab8bf1f94392e68bd3feea700f26b1c5 346 Pfam PF01628 HrcA protein C terminal domain 102 313 3.7E-24 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 SPSF3K_RS10140 ab8bf1f94392e68bd3feea700f26b1c5 346 Gene3D G3DSA:1.10.10.10 1 83 5.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10140 ab8bf1f94392e68bd3feea700f26b1c5 346 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 322 25.603 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SPSF3K_RS10140 ab8bf1f94392e68bd3feea700f26b1c5 346 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 328 1.1E-78 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SPSF3K_RS10140 ab8bf1f94392e68bd3feea700f26b1c5 346 SUPERFAMILY SSF46785 1 81 1.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10140 ab8bf1f94392e68bd3feea700f26b1c5 346 SUPERFAMILY SSF55781 69 333 1.12E-27 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 Gene3D G3DSA:1.20.120.220 69 235 1.2E-35 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 15 231 2.1E-42 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 SUPERFAMILY SSF81336 72 228 1.28E-34 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 235 13.289 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 PRINTS PR00123 ATP synthase A subunit signature 215 230 4.6E-22 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 PRINTS PR00123 ATP synthase A subunit signature 78 94 4.6E-22 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 PRINTS PR00123 ATP synthase A subunit signature 146 161 4.6E-22 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 PRINTS PR00123 ATP synthase A subunit signature 162 184 4.6E-22 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04885 ca177c0929dc873ddb561014c1ee385a 237 Pfam PF00119 ATP synthase A chain 21 228 1.9E-46 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS07870 58ace26bfdfd991e8d9548f66414e5b2 126 Gene3D G3DSA:1.10.1660.10 1 55 2.7E-19 T 29-03-2018 SPSF3K_RS07870 58ace26bfdfd991e8d9548f66414e5b2 126 Gene3D G3DSA:1.10.1660.10 56 125 2.5E-12 T 29-03-2018 SPSF3K_RS07870 58ace26bfdfd991e8d9548f66414e5b2 126 SMART SM00422 1 70 1.3E-23 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS07870 58ace26bfdfd991e8d9548f66414e5b2 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 4.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS07870 58ace26bfdfd991e8d9548f66414e5b2 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS07870 58ace26bfdfd991e8d9548f66414e5b2 126 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS07870 58ace26bfdfd991e8d9548f66414e5b2 126 Pfam PF00376 MerR family regulatory protein 2 39 4.5E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS07870 58ace26bfdfd991e8d9548f66414e5b2 126 SUPERFAMILY SSF46955 1 118 2.6E-32 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 SUPERFAMILY SSF52518 6 326 1.89E-117 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 Gene3D G3DSA:3.40.50.970 362 539 4.2E-42 T 29-03-2018 SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 Pfam PF02779 Transketolase, pyrimidine binding domain 355 522 3.0E-42 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 Pfam PF02780 Transketolase, C-terminal domain 550 652 1.3E-10 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 Gene3D G3DSA:3.40.50.970 3 361 1.9E-108 T 29-03-2018 SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 SMART SM00861 352 523 6.5E-59 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 334 6.8E-147 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 TIGRFAM TIGR00232 tktlase_bact: transketolase 10 660 8.8E-277 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 SUPERFAMILY SSF52518 343 524 3.44E-63 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 SUPERFAMILY SSF52922 532 660 3.53E-38 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 ProSitePatterns PS00802 Transketolase signature 2. 465 481 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 ProSitePatterns PS00801 Transketolase signature 1. 15 35 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 SPSF3K_RS09825 182589fdae4a53d5d1bba25b8637cd97 661 Gene3D G3DSA:3.40.50.920 540 660 1.0E-24 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPSF3K_RS07000 f02d5cad2775f6af6d11e24e5d44c69b 510 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS07000 f02d5cad2775f6af6d11e24e5d44c69b 510 Gene3D G3DSA:3.40.50.300 251 494 3.0E-38 T 29-03-2018 SPSF3K_RS07000 f02d5cad2775f6af6d11e24e5d44c69b 510 Pfam PF00005 ABC transporter 275 430 7.6E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS07000 f02d5cad2775f6af6d11e24e5d44c69b 510 Pfam PF00005 ABC transporter 22 170 6.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS07000 f02d5cad2775f6af6d11e24e5d44c69b 510 SMART SM00382 30 218 2.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS07000 f02d5cad2775f6af6d11e24e5d44c69b 510 Gene3D G3DSA:3.40.50.300 2 239 2.7E-54 T 29-03-2018 SPSF3K_RS07000 f02d5cad2775f6af6d11e24e5d44c69b 510 SUPERFAMILY SSF52540 4 229 2.27E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07000 f02d5cad2775f6af6d11e24e5d44c69b 510 SUPERFAMILY SSF52540 257 489 4.28E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08780 95905c37bb6192c35b1350704d8e1864 91 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.5E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SPSF3K_RS08780 95905c37bb6192c35b1350704d8e1864 91 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.5E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SPSF3K_RS08780 95905c37bb6192c35b1350704d8e1864 91 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.5E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SPSF3K_RS08780 95905c37bb6192c35b1350704d8e1864 91 Pfam PF00216 Bacterial DNA-binding protein 3 91 3.6E-34 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SPSF3K_RS08780 95905c37bb6192c35b1350704d8e1864 91 SMART SM00411 2 91 1.6E-46 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 SPSF3K_RS08780 95905c37bb6192c35b1350704d8e1864 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SPSF3K_RS08780 95905c37bb6192c35b1350704d8e1864 91 SUPERFAMILY SSF47729 3 91 3.39E-32 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SPSF3K_RS08780 95905c37bb6192c35b1350704d8e1864 91 Gene3D G3DSA:4.10.520.10 1 91 1.0E-34 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SPSF3K_RS10185 3f03fed9dfbf9f19ee6f8b0420a04a4f 306 SUPERFAMILY SSF103481 198 292 9.68E-10 T 29-03-2018 SPSF3K_RS10185 3f03fed9dfbf9f19ee6f8b0420a04a4f 306 SUPERFAMILY SSF103481 41 147 1.31E-9 T 29-03-2018 SPSF3K_RS10185 3f03fed9dfbf9f19ee6f8b0420a04a4f 306 Pfam PF00892 EamA-like transporter family 157 289 2.4E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SPSF3K_RS10185 3f03fed9dfbf9f19ee6f8b0420a04a4f 306 Pfam PF00892 EamA-like transporter family 5 143 9.4E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 Gene3D G3DSA:3.30.1360.60 475 551 1.6E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 580 704 4.1E-46 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 7 553 0.0 T 29-03-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 Pfam PF02378 Phosphotransferase system, EIIC 19 382 5.6E-53 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 Gene3D G3DSA:2.70.70.10 567 727 5.0E-51 T 29-03-2018 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 Pfam PF00367 phosphotransferase system, EIIB 480 511 2.1E-13 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 SUPERFAMILY SSF55604 478 551 3.27E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 443 537 4.7E-16 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 643 655 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 582 701 2.6E-39 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS02455 cf97fcb478982fe8fae5486950e78b1f 727 SUPERFAMILY SSF51261 578 718 1.38E-48 T 29-03-2018 IPR011055 Duplicated hybrid motif SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 SUPERFAMILY SSF53067 6 195 1.84E-54 T 29-03-2018 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 1.1E-96 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 PIRSF PIRSF003101 1 454 1.1E-126 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 Gene3D G3DSA:3.30.1490.110 90 163 1.3E-23 T 29-03-2018 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 Pfam PF14450 Cell division protein FtsA 9 176 2.7E-8 T 29-03-2018 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 Pfam PF14450 Cell division protein FtsA 206 365 5.0E-18 T 29-03-2018 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 Gene3D G3DSA:3.30.420.40 195 348 2.9E-19 T 29-03-2018 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 Pfam PF11983 Membrane-attachment and polymerisation-promoting switch 377 455 6.4E-21 T 29-03-2018 IPR021873 Cell division protein FtsA, C-terminal SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 454 27.551 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 SMART SM00842 7 194 1.3E-85 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 SUPERFAMILY SSF53067 197 365 7.92E-38 T 29-03-2018 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 Gene3D G3DSA:3.30.420.40 1 80 2.0E-7 T 29-03-2018 SPSF3K_RS08920 de97e1b6270e33b493a227df28ac6b39 455 Pfam PF02491 SHS2 domain inserted in FTSA 84 160 3.2E-21 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 SPSF3K_RS08370 a365a0ab063035d372d5d240f49d865e 158 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 3 107 2.4E-19 T 29-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 SPSF3K_RS08370 a365a0ab063035d372d5d240f49d865e 158 Gene3D G3DSA:3.40.50.450 1 158 9.1E-35 T 29-03-2018 SPSF3K_RS08370 a365a0ab063035d372d5d240f49d865e 158 SUPERFAMILY SSF52309 1 141 1.16E-29 T 29-03-2018 SPSF3K_RS10950 e62f354fa21310ed3a6eb039b2e58c85 200 SUPERFAMILY SSF140931 18 177 2.35E-37 T 29-03-2018 IPR003812 Fido domain SPSF3K_RS10950 e62f354fa21310ed3a6eb039b2e58c85 200 Pfam PF02661 Fic/DOC family 46 130 4.8E-12 T 29-03-2018 IPR003812 Fido domain SPSF3K_RS10950 e62f354fa21310ed3a6eb039b2e58c85 200 Gene3D G3DSA:1.10.3290.10 9 172 2.2E-32 T 29-03-2018 IPR003812 Fido domain SPSF3K_RS11030 e62f354fa21310ed3a6eb039b2e58c85 200 SUPERFAMILY SSF140931 18 177 2.35E-37 T 29-03-2018 IPR003812 Fido domain SPSF3K_RS11030 e62f354fa21310ed3a6eb039b2e58c85 200 Pfam PF02661 Fic/DOC family 46 130 4.8E-12 T 29-03-2018 IPR003812 Fido domain SPSF3K_RS11030 e62f354fa21310ed3a6eb039b2e58c85 200 Gene3D G3DSA:1.10.3290.10 9 172 2.2E-32 T 29-03-2018 IPR003812 Fido domain SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 Pfam PF13545 Crp-like helix-turn-helix domain 148 216 1.1E-18 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 Pfam PF00027 Cyclic nucleotide-binding domain 31 115 5.7E-16 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 184 199 7.3E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 168 184 7.3E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 SUPERFAMILY SSF46785 146 216 2.24E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 Gene3D G3DSA:2.60.120.10 2 144 1.6E-26 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 Gene3D G3DSA:1.10.10.10 145 217 3.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 SMART SM00100 12 131 1.1E-14 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 SMART SM00419 162 210 8.7E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02755 9f272009daf70deba33a6b143a7122a4 217 SUPERFAMILY SSF51206 10 141 1.17E-30 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SPSF3K_RS07245 aeee16e8bc44150bc2a5acc28fc458bf 591 SUPERFAMILY SSF52794 385 475 1.55E-21 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS07245 aeee16e8bc44150bc2a5acc28fc458bf 591 SUPERFAMILY SSF52794 501 590 3.14E-10 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS07245 aeee16e8bc44150bc2a5acc28fc458bf 591 Pfam PF02378 Phosphotransferase system, EIIC 19 277 4.4E-14 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS07245 aeee16e8bc44150bc2a5acc28fc458bf 591 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 387 471 1.3E-7 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS07245 aeee16e8bc44150bc2a5acc28fc458bf 591 Gene3D G3DSA:3.40.50.2300 500 591 3.0E-5 T 29-03-2018 SPSF3K_RS07245 aeee16e8bc44150bc2a5acc28fc458bf 591 Gene3D G3DSA:3.40.50.2300 373 479 1.3E-14 T 29-03-2018 SPSF3K_RS07245 aeee16e8bc44150bc2a5acc28fc458bf 591 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 10 350 1.5E-151 T 29-03-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 SPSF3K_RS08175 301bacadfcc7189a0ff113122348f053 58 Pfam PF11240 Protein of unknown function (DUF3042) 5 57 2.2E-22 T 29-03-2018 IPR021402 Protein of unknown function DUF3042 SPSF3K_RS06385 42a6e267976643a9b60a1d7f5e222543 419 Pfam PF00464 Serine hydroxymethyltransferase 9 386 1.2E-166 T 29-03-2018 SPSF3K_RS06385 42a6e267976643a9b60a1d7f5e222543 419 PIRSF PIRSF000412 1 419 5.9E-160 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SPSF3K_RS06385 42a6e267976643a9b60a1d7f5e222543 419 Gene3D G3DSA:3.40.640.10 37 274 3.2E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPSF3K_RS06385 42a6e267976643a9b60a1d7f5e222543 419 SUPERFAMILY SSF53383 6 417 9.91E-171 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase SPSF3K_RS06385 42a6e267976643a9b60a1d7f5e222543 419 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SPSF3K_RS06385 42a6e267976643a9b60a1d7f5e222543 419 Gene3D G3DSA:3.90.1150.10 275 416 1.3E-48 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 SPSF3K_RS06385 42a6e267976643a9b60a1d7f5e222543 419 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 50.89 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 SPSF3K_RS06365 e95476ed7101162cc2596d5474fd9e2f 359 SMART SM00937 65 180 1.2E-57 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 SPSF3K_RS06365 e95476ed7101162cc2596d5474fd9e2f 359 Gene3D G3DSA:3.30.160.20 211 296 3.4E-26 T 29-03-2018 SPSF3K_RS06365 e95476ed7101162cc2596d5474fd9e2f 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 358 1.1E-154 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SPSF3K_RS06365 e95476ed7101162cc2596d5474fd9e2f 359 Pfam PF03462 PCRF domain 11 205 8.4E-70 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 SPSF3K_RS06365 e95476ed7101162cc2596d5474fd9e2f 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SPSF3K_RS06365 e95476ed7101162cc2596d5474fd9e2f 359 SUPERFAMILY SSF75620 10 354 2.22E-124 T 29-03-2018 SPSF3K_RS06365 e95476ed7101162cc2596d5474fd9e2f 359 Pfam PF00472 RF-1 domain 213 322 1.6E-36 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SPSF3K_RS06365 e95476ed7101162cc2596d5474fd9e2f 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 358 38.432 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SPSF3K_RS06365 e95476ed7101162cc2596d5474fd9e2f 359 Gene3D G3DSA:1.20.58.410 1 102 1.6E-15 T 29-03-2018 SPSF3K_RS05525 b1f7733ce3f82f110f5791fdef18814a 864 SUPERFAMILY SSF54001 747 841 7.75E-15 T 29-03-2018 SPSF3K_RS05525 b1f7733ce3f82f110f5791fdef18814a 864 Pfam PF05257 CHAP domain 750 838 7.5E-12 T 29-03-2018 IPR007921 CHAP domain SPSF3K_RS05525 b1f7733ce3f82f110f5791fdef18814a 864 Gene3D G3DSA:2.70.70.10 4 510 2.7E-9 T 29-03-2018 SPSF3K_RS05525 b1f7733ce3f82f110f5791fdef18814a 864 SUPERFAMILY SSF51261 348 480 1.62E-9 T 29-03-2018 IPR011055 Duplicated hybrid motif SPSF3K_RS05525 b1f7733ce3f82f110f5791fdef18814a 864 Pfam PF01551 Peptidase family M23 417 491 4.0E-7 T 29-03-2018 IPR016047 Peptidase M23 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 Pfam PF08544 GHMP kinases C terminal 284 365 3.2E-13 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 Hamap MF_00246 Galactokinase [galK]. 24 386 48.977 T 29-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 SUPERFAMILY SSF55060 206 386 1.98E-53 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 PRINTS PR00473 Galactokinase signature 91 102 1.2E-28 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 PRINTS PR00473 Galactokinase signature 269 283 1.2E-28 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 PRINTS PR00473 Galactokinase signature 26 44 1.2E-28 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 PRINTS PR00473 Galactokinase signature 112 130 1.2E-28 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 PRINTS PR00959 Mevalonate kinase family signature 162 181 5.5E-43 T 29-03-2018 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 PRINTS PR00959 Mevalonate kinase family signature 119 141 5.5E-43 T 29-03-2018 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 PRINTS PR00959 Mevalonate kinase family signature 24 48 5.5E-43 T 29-03-2018 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 PRINTS PR00959 Mevalonate kinase family signature 333 350 5.5E-43 T 29-03-2018 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 SUPERFAMILY SSF54211 5 203 7.44E-60 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 Pfam PF10509 Galactokinase galactose-binding signature 8 57 2.0E-22 T 29-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 PIRSF PIRSF000530 2 387 1.4E-120 T 29-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 Gene3D G3DSA:3.30.70.890 209 386 1.5E-49 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 TIGRFAM TIGR00131 gal_kin: galactokinase 5 384 1.9E-118 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 29-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 Gene3D G3DSA:3.30.230.10 3 208 2.2E-53 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS02530 2b9c6a996d91e5d285ae4fb96ba00a58 387 Pfam PF00288 GHMP kinases N terminal domain 114 181 7.3E-11 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SPSF3K_RS08450 da39d9f40fe9f823d18a7aad270ce9f9 427 Gene3D G3DSA:3.65.10.10 19 218 4.3E-49 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SPSF3K_RS08450 da39d9f40fe9f823d18a7aad270ce9f9 427 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SPSF3K_RS08450 da39d9f40fe9f823d18a7aad270ce9f9 427 Gene3D G3DSA:3.65.10.10 219 426 5.3E-48 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SPSF3K_RS08450 da39d9f40fe9f823d18a7aad270ce9f9 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 427 32.352 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SPSF3K_RS08450 da39d9f40fe9f823d18a7aad270ce9f9 427 SUPERFAMILY SSF55205 5 424 1.2E-126 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SPSF3K_RS08450 da39d9f40fe9f823d18a7aad270ce9f9 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 425 3.7E-121 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SPSF3K_RS08450 da39d9f40fe9f823d18a7aad270ce9f9 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 421 5.5E-115 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 SPSF3K_RS08450 da39d9f40fe9f823d18a7aad270ce9f9 427 ProSitePatterns PS00885 EPSP synthase signature 2. 337 355 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SPSF3K_RS08450 da39d9f40fe9f823d18a7aad270ce9f9 427 PIRSF PIRSF000505 1 427 5.2E-110 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 Gene3D G3DSA:1.10.730.10 634 807 2.0E-38 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 Pfam PF08264 Anticodon-binding domain of tRNA 678 831 2.1E-26 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 SUPERFAMILY SSF52374 1 200 2.15E-148 T 29-03-2018 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 SUPERFAMILY SSF52374 394 640 2.15E-148 T 29-03-2018 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 SUPERFAMILY SSF50677 202 393 6.91E-44 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 3.4E-27 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 3.4E-27 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 3.4E-27 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 520 533 3.4E-27 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 554 563 3.4E-27 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 Gene3D G3DSA:3.30.2320.20 808 884 1.2E-21 T 29-03-2018 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 SUPERFAMILY SSF47323 645 917 1.23E-68 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 917 19.122 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 Gene3D G3DSA:3.40.50.620 18 633 6.1E-134 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 633 7.0E-198 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS08885 c566ee86538d612f2af0ea8a9f398be9 931 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 834 1.2E-281 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 SPSF3K_RS06015 2d051c9c59a6c108268ada83f68d8c20 74 Gene3D G3DSA:1.10.3100.10 2 74 2.9E-18 T 29-03-2018 IPR027910 YdiL-like domain SPSF3K_RS06015 2d051c9c59a6c108268ada83f68d8c20 74 SMART SM00530 4 59 8.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS06015 2d051c9c59a6c108268ada83f68d8c20 74 Pfam PF01381 Helix-turn-helix 5 59 6.4E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS06015 2d051c9c59a6c108268ada83f68d8c20 74 SUPERFAMILY SSF47413 3 64 1.1E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS03530 9de07ffd8af6fdb64a6b46b4eba9b35d 444 Gene3D G3DSA:3.30.465.10 345 436 3.5E-16 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SPSF3K_RS03530 9de07ffd8af6fdb64a6b46b4eba9b35d 444 SUPERFAMILY SSF54631 203 340 1.77E-29 T 29-03-2018 SPSF3K_RS03530 9de07ffd8af6fdb64a6b46b4eba9b35d 444 SUPERFAMILY SSF56176 353 433 7.63E-17 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SPSF3K_RS03530 9de07ffd8af6fdb64a6b46b4eba9b35d 444 Pfam PF03471 Transporter associated domain 354 433 5.7E-15 T 29-03-2018 IPR005170 Transporter-associated domain SPSF3K_RS03530 9de07ffd8af6fdb64a6b46b4eba9b35d 444 Pfam PF00571 CBS domain 289 337 3.8E-6 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS03530 9de07ffd8af6fdb64a6b46b4eba9b35d 444 Pfam PF00571 CBS domain 218 272 7.2E-6 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS03530 9de07ffd8af6fdb64a6b46b4eba9b35d 444 SMART SM01091 352 436 3.2E-12 T 29-03-2018 IPR005170 Transporter-associated domain SPSF3K_RS03530 9de07ffd8af6fdb64a6b46b4eba9b35d 444 Pfam PF01595 Domain of unknown function DUF21 15 200 2.4E-45 T 29-03-2018 IPR002550 Domain of unknown function DUF21 SPSF3K_RS03530 9de07ffd8af6fdb64a6b46b4eba9b35d 444 Gene3D G3DSA:3.10.580.10 195 344 6.8E-32 T 29-03-2018 SPSF3K_RS10160 6cd7692b3318aaceb35e2ba8bc749734 445 Hamap MF_01221 UPF0210 protein . 1 445 51.57 T 29-03-2018 IPR007841 Uncharacterised protein family UPF0210 SPSF3K_RS10160 6cd7692b3318aaceb35e2ba8bc749734 445 Gene3D G3DSA:3.20.70.20 13 422 8.0E-177 T 29-03-2018 SPSF3K_RS10160 6cd7692b3318aaceb35e2ba8bc749734 445 SUPERFAMILY SSF51998 2 440 4.39E-177 T 29-03-2018 SPSF3K_RS10160 6cd7692b3318aaceb35e2ba8bc749734 445 Pfam PF05167 Uncharacterised ACR (DUF711) 12 409 3.5E-170 T 29-03-2018 IPR007841 Uncharacterised protein family UPF0210 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 Gene3D G3DSA:3.40.50.620 1 307 2.1E-93 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 2.8E-133 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 447 37.389 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 SUPERFAMILY SSF47323 331 446 1.03E-30 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 446 2.6E-167 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 Gene3D G3DSA:1.20.120.640 308 390 5.7E-12 T 29-03-2018 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 SUPERFAMILY SSF52374 2 314 1.5E-99 T 29-03-2018 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 SMART SM00840 344 406 2.5E-14 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 7.7E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 7.7E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 7.7E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 7.7E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SPSF3K_RS02645 2914f19bd715b793b41ef7557687d9fa 447 Pfam PF09190 DALR domain 344 396 6.3E-16 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SPSF3K_RS00805 b9b35475bd15389973a20d554b0b072a 146 SMART SM00881 16 111 1.2E-19 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SPSF3K_RS00805 b9b35475bd15389973a20d554b0b072a 146 Gene3D G3DSA:3.40.50.720 17 143 2.5E-31 T 29-03-2018 SPSF3K_RS00805 b9b35475bd15389973a20d554b0b072a 146 Pfam PF13380 CoA binding domain 22 138 5.5E-35 T 29-03-2018 IPR003781 CoA-binding GO:0048037 SPSF3K_RS00805 b9b35475bd15389973a20d554b0b072a 146 SUPERFAMILY SSF51735 10 139 2.56E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS00125 1f844b8199858427effd2efa8a21c965 373 Gene3D G3DSA:2.30.30.280 214 281 1.1E-25 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 SPSF3K_RS00125 1f844b8199858427effd2efa8a21c965 373 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 8 360 2.4E-136 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SPSF3K_RS00125 1f844b8199858427effd2efa8a21c965 373 Gene3D G3DSA:2.40.30.10 283 373 3.4E-28 T 29-03-2018 SPSF3K_RS00125 1f844b8199858427effd2efa8a21c965 373 SUPERFAMILY SSF52402 5 244 2.01E-58 T 29-03-2018 SPSF3K_RS00125 1f844b8199858427effd2efa8a21c965 373 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 361 40.864 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 SPSF3K_RS00125 1f844b8199858427effd2efa8a21c965 373 Pfam PF03054 tRNA methyl transferase 8 360 2.3E-146 T 29-03-2018 SPSF3K_RS00125 1f844b8199858427effd2efa8a21c965 373 Gene3D G3DSA:3.40.50.620 2 213 3.6E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS10020 dfe4dcbbd80258b6d4424271194d8437 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 237 5.9E-25 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS10020 dfe4dcbbd80258b6d4424271194d8437 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 265 1.0E-60 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS10020 dfe4dcbbd80258b6d4424271194d8437 270 Gene3D G3DSA:3.40.50.1000 1 270 1.8E-32 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS10020 dfe4dcbbd80258b6d4424271194d8437 270 SUPERFAMILY SSF56784 1 269 2.36E-61 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS10020 dfe4dcbbd80258b6d4424271194d8437 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 8.1E-52 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS03570 2cb6b107ec1d186101fd94fecc973ed9 260 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS03570 2cb6b107ec1d186101fd94fecc973ed9 260 SMART SM00382 28 217 4.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS03570 2cb6b107ec1d186101fd94fecc973ed9 260 Gene3D G3DSA:3.40.50.300 1 241 1.3E-57 T 29-03-2018 SPSF3K_RS03570 2cb6b107ec1d186101fd94fecc973ed9 260 SUPERFAMILY SSF52540 3 229 2.97E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03570 2cb6b107ec1d186101fd94fecc973ed9 260 Pfam PF00005 ABC transporter 19 167 8.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS10270 f77b1891c7892e1fb844af4ebd258d6d 304 Pfam PF08448 PAS fold 37 140 5.6E-7 T 29-03-2018 IPR013656 PAS fold-4 SPSF3K_RS10270 f77b1891c7892e1fb844af4ebd258d6d 304 Pfam PF00990 Diguanylate cyclase, GGDEF domain 151 297 2.4E-29 T 29-03-2018 IPR000160 GGDEF domain SPSF3K_RS10270 f77b1891c7892e1fb844af4ebd258d6d 304 Gene3D G3DSA:3.30.70.270 144 302 2.2E-31 T 29-03-2018 SPSF3K_RS10270 f77b1891c7892e1fb844af4ebd258d6d 304 SMART SM00267 138 302 3.8E-22 T 29-03-2018 IPR000160 GGDEF domain SPSF3K_RS10270 f77b1891c7892e1fb844af4ebd258d6d 304 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 151 297 2.8E-31 T 29-03-2018 IPR000160 GGDEF domain SPSF3K_RS10270 f77b1891c7892e1fb844af4ebd258d6d 304 SUPERFAMILY SSF55785 38 139 5.41E-7 T 29-03-2018 IPR000014 PAS domain SPSF3K_RS10270 f77b1891c7892e1fb844af4ebd258d6d 304 SUPERFAMILY SSF55073 155 297 2.28E-28 T 29-03-2018 IPR029787 Nucleotide cyclase SPSF3K_RS10270 f77b1891c7892e1fb844af4ebd258d6d 304 Gene3D G3DSA:3.30.450.20 10 143 5.1E-9 T 29-03-2018 SPSF3K_RS09710 7d183eedafe33e1c2b02809ec6cca3aa 107 PIRSF PIRSF029938 1 107 7.6E-44 T 29-03-2018 IPR011229 Cell cycle protein GpsB SPSF3K_RS09710 7d183eedafe33e1c2b02809ec6cca3aa 107 Pfam PF05103 DivIVA protein 6 64 5.1E-17 T 29-03-2018 IPR007793 DivIVA family SPSF3K_RS09710 7d183eedafe33e1c2b02809ec6cca3aa 107 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 1 103 23.952 T 29-03-2018 IPR011229 Cell cycle protein GpsB SPSF3K_RS09710 7d183eedafe33e1c2b02809ec6cca3aa 107 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 7 39 9.8E-15 T 29-03-2018 IPR019933 DivIVA domain SPSF3K_RS04705 87977c3bf029f5262dccbf7d6fc48b61 574 Gene3D G3DSA:1.20.1170.10 26 304 8.1E-5 T 29-03-2018 SPSF3K_RS04705 87977c3bf029f5262dccbf7d6fc48b61 574 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 6 568 22.688 T 29-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 SPSF3K_RS04705 87977c3bf029f5262dccbf7d6fc48b61 574 Pfam PF06160 Septation ring formation regulator, EzrA 8 565 1.0E-174 T 29-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 SPSF3K_RS03935 91609b80eb1b6cd29d896945a09ec5be 210 Pfam PF00005 ABC transporter 17 157 2.2E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS03935 91609b80eb1b6cd29d896945a09ec5be 210 SUPERFAMILY SSF52540 2 207 2.44E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03935 91609b80eb1b6cd29d896945a09ec5be 210 Gene3D G3DSA:3.40.50.300 1 210 1.1E-35 T 29-03-2018 SPSF3K_RS03935 91609b80eb1b6cd29d896945a09ec5be 210 SMART SM00382 26 203 3.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 372 380 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 4.1E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 4.1E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 4.1E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 4.1E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 432 4.1E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 SUPERFAMILY SSF51445 5 476 2.21E-157 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 Pfam PF00232 Glycosyl hydrolase family 1 4 475 3.4E-131 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS06220 c564dda81eaa72187c1461d010bc80a8 479 Gene3D G3DSA:3.20.20.80 4 479 3.4E-150 T 29-03-2018 SPSF3K_RS07270 6ff08e56376d3dc613a38e4a44ec13c0 1034 Gene3D G3DSA:2.40.50.140 869 964 1.8E-15 T 29-03-2018 SPSF3K_RS07270 6ff08e56376d3dc613a38e4a44ec13c0 1034 Pfam PF01336 OB-fold nucleic acid binding domain 897 963 7.6E-10 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SPSF3K_RS07270 6ff08e56376d3dc613a38e4a44ec13c0 1034 SUPERFAMILY SSF89550 9 70 3.53E-5 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SPSF3K_RS07270 6ff08e56376d3dc613a38e4a44ec13c0 1034 Pfam PF02811 PHP domain 7 116 7.7E-18 T 29-03-2018 IPR004013 PHP domain GO:0003824 SPSF3K_RS07270 6ff08e56376d3dc613a38e4a44ec13c0 1034 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 145 925 1.4E-205 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS07270 6ff08e56376d3dc613a38e4a44ec13c0 1034 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 241 657 2.5E-154 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS07270 6ff08e56376d3dc613a38e4a44ec13c0 1034 SMART SM00481 3 70 6.4E-7 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal SPSF3K_RS07270 6ff08e56376d3dc613a38e4a44ec13c0 1034 Gene3D G3DSA:3.20.20.140 1 297 9.1E-15 T 29-03-2018 SPSF3K_RS07270 6ff08e56376d3dc613a38e4a44ec13c0 1034 Pfam PF14579 Helix-hairpin-helix motif 728 810 2.9E-9 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS08705 6de88a69db5d2048ecee255d6b471368 258 SUPERFAMILY SSF56784 5 256 3.07E-54 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08705 6de88a69db5d2048ecee255d6b471368 258 ProSitePatterns PS01229 Hypothetical cof family signature 2. 206 228 - T 29-03-2018 SPSF3K_RS08705 6de88a69db5d2048ecee255d6b471368 258 Gene3D G3DSA:3.40.50.1000 1 257 7.6E-35 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08705 6de88a69db5d2048ecee255d6b471368 258 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 250 7.5E-50 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS08705 6de88a69db5d2048ecee255d6b471368 258 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 225 5.8E-24 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS08705 6de88a69db5d2048ecee255d6b471368 258 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 249 3.8E-50 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07710 2068ba2df5f52a02ae06a78e5e0e6901 365 Gene3D G3DSA:3.40.50.2000 2 180 2.5E-9 T 29-03-2018 SPSF3K_RS07710 2068ba2df5f52a02ae06a78e5e0e6901 365 Gene3D G3DSA:3.40.50.2000 181 347 1.1E-34 T 29-03-2018 SPSF3K_RS07710 2068ba2df5f52a02ae06a78e5e0e6901 365 Pfam PF00534 Glycosyl transferases group 1 184 339 6.9E-27 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SPSF3K_RS07710 2068ba2df5f52a02ae06a78e5e0e6901 365 Pfam PF13477 Glycosyl transferase 4-like 3 147 1.1E-29 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SPSF3K_RS07710 2068ba2df5f52a02ae06a78e5e0e6901 365 SUPERFAMILY SSF53756 19 363 5.34E-62 T 29-03-2018 SPSF3K_RS06375 145994b892f88260001c18fead955793 196 SUPERFAMILY SSF55821 2 193 4.58E-53 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SPSF3K_RS06375 145994b892f88260001c18fead955793 196 Pfam PF01300 Telomere recombination 7 180 3.2E-46 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 SPSF3K_RS06375 145994b892f88260001c18fead955793 196 Gene3D G3DSA:3.90.870.10 1 196 2.2E-57 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain SPSF3K_RS06375 145994b892f88260001c18fead955793 196 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 2 187 1.4E-51 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 SPSF3K_RS05110 1b42ca2f2b7784def287b6d14cd1b7a7 176 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 11 80 4.7E-28 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SPSF3K_RS05110 1b42ca2f2b7784def287b6d14cd1b7a7 176 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 5 174 29.253 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SPSF3K_RS05110 1b42ca2f2b7784def287b6d14cd1b7a7 176 ProSitePatterns PS00938 Initiation factor 3 signature. 62 75 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 SPSF3K_RS05110 1b42ca2f2b7784def287b6d14cd1b7a7 176 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 87 171 1.8E-34 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SPSF3K_RS05110 1b42ca2f2b7784def287b6d14cd1b7a7 176 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 11 171 5.8E-62 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SPSF3K_RS05110 1b42ca2f2b7784def287b6d14cd1b7a7 176 SUPERFAMILY SSF54364 9 82 2.88E-27 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 SPSF3K_RS05110 1b42ca2f2b7784def287b6d14cd1b7a7 176 Gene3D G3DSA:3.10.20.80 6 82 8.0E-28 T 29-03-2018 SPSF3K_RS05110 1b42ca2f2b7784def287b6d14cd1b7a7 176 Gene3D G3DSA:3.30.110.10 83 176 4.1E-31 T 29-03-2018 SPSF3K_RS05110 1b42ca2f2b7784def287b6d14cd1b7a7 176 SUPERFAMILY SSF55200 86 174 2.35E-30 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 SPSF3K_RS09020 aca28828f8c81c695b22d3955f9746e9 132 Pfam PF05025 RbsD / FucU transport protein family 1 131 4.6E-46 T 29-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 SPSF3K_RS09020 aca28828f8c81c695b22d3955f9746e9 132 Gene3D G3DSA:3.40.1650.10 2 132 4.6E-37 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 SPSF3K_RS09020 aca28828f8c81c695b22d3955f9746e9 132 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 132 31.496 T 29-03-2018 IPR023064 D-ribose pyranase GO:0016872 SPSF3K_RS09020 aca28828f8c81c695b22d3955f9746e9 132 SUPERFAMILY SSF102546 1 131 1.83E-42 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 SPSF3K_RS00715 1f64df9b2eb231e6010a97ac7649980e 50 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 50 15.27 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00715 1f64df9b2eb231e6010a97ac7649980e 50 SUPERFAMILY SSF57829 4 50 1.37E-13 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 SPSF3K_RS00715 1f64df9b2eb231e6010a97ac7649980e 50 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 50 3.8E-13 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00715 1f64df9b2eb231e6010a97ac7649980e 50 Pfam PF00471 Ribosomal protein L33 5 50 2.9E-15 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS02245 c419546b8798d8e13bc9d5403fa17016 217 Pfam PF00230 Major intrinsic protein 2 207 1.5E-45 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS02245 c419546b8798d8e13bc9d5403fa17016 217 Gene3D G3DSA:1.20.1080.10 1 217 1.3E-58 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS02245 c419546b8798d8e13bc9d5403fa17016 217 PRINTS PR00783 Major intrinsic protein family signature 122 140 5.2E-46 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS02245 c419546b8798d8e13bc9d5403fa17016 217 PRINTS PR00783 Major intrinsic protein family signature 73 92 5.2E-46 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS02245 c419546b8798d8e13bc9d5403fa17016 217 PRINTS PR00783 Major intrinsic protein family signature 36 60 5.2E-46 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS02245 c419546b8798d8e13bc9d5403fa17016 217 PRINTS PR00783 Major intrinsic protein family signature 2 21 5.2E-46 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS02245 c419546b8798d8e13bc9d5403fa17016 217 PRINTS PR00783 Major intrinsic protein family signature 153 175 5.2E-46 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS02245 c419546b8798d8e13bc9d5403fa17016 217 PRINTS PR00783 Major intrinsic protein family signature 192 212 5.2E-46 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS02245 c419546b8798d8e13bc9d5403fa17016 217 SUPERFAMILY SSF81338 2 213 4.58E-55 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS03890 e8ed77ede812e419db2e8a42fd1cee50 191 Pfam PF03167 Uracil DNA glycosylase superfamily 28 181 4.3E-20 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS03890 e8ed77ede812e419db2e8a42fd1cee50 191 SMART SM00986 24 182 1.3E-20 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS03890 e8ed77ede812e419db2e8a42fd1cee50 191 SMART SM00987 24 182 1.3E-20 T 29-03-2018 SPSF3K_RS03890 e8ed77ede812e419db2e8a42fd1cee50 191 SUPERFAMILY SSF52141 1 189 4.58E-47 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS03890 e8ed77ede812e419db2e8a42fd1cee50 191 Gene3D G3DSA:3.40.470.10 1 191 2.0E-37 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS08640 4a164dd027d0d42e54474f47e80ac4d8 238 SUPERFAMILY SSF55120 49 230 1.41E-41 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS08640 4a164dd027d0d42e54474f47e80ac4d8 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 227 9.1E-44 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPSF3K_RS08640 4a164dd027d0d42e54474f47e80ac4d8 238 Pfam PF01479 S4 domain 1 47 3.7E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08640 4a164dd027d0d42e54474f47e80ac4d8 238 Gene3D G3DSA:3.10.290.10 1 70 3.4E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08640 4a164dd027d0d42e54474f47e80ac4d8 238 SMART SM00363 1 69 1.1E-6 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS08640 4a164dd027d0d42e54474f47e80ac4d8 238 Gene3D G3DSA:3.30.2350.10 71 238 2.1E-34 T 29-03-2018 SPSF3K_RS08640 4a164dd027d0d42e54474f47e80ac4d8 238 SUPERFAMILY SSF55174 1 56 8.41E-11 T 29-03-2018 SPSF3K_RS08640 4a164dd027d0d42e54474f47e80ac4d8 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPSF3K_RS08640 4a164dd027d0d42e54474f47e80ac4d8 238 Pfam PF00849 RNA pseudouridylate synthase 61 195 2.5E-19 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS07825 b4de0ed630bb109520539cf660f89009 228 Gene3D G3DSA:3.40.50.880 1 228 7.3E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS07825 b4de0ed630bb109520539cf660f89009 228 Pfam PF01965 DJ-1/PfpI family 26 215 1.5E-8 T 29-03-2018 IPR002818 DJ-1/PfpI SPSF3K_RS07825 b4de0ed630bb109520539cf660f89009 228 SUPERFAMILY SSF52317 1 226 1.73E-62 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS00750 34dfc1b3ad7a228ad6a8a612e154d072 92 SUPERFAMILY SSF52794 1 91 4.71E-20 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS00750 34dfc1b3ad7a228ad6a8a612e154d072 92 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 90 9.8E-18 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS00750 34dfc1b3ad7a228ad6a8a612e154d072 92 Gene3D G3DSA:3.40.50.2300 1 92 2.6E-18 T 29-03-2018 SPSF3K_RS07650 a05dafa4a4630b4d4f777dc8aba12e7a 209 SUPERFAMILY SSF53271 6 206 9.57E-50 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS07650 a05dafa4a4630b4d4f777dc8aba12e7a 209 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 209 29.619 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS07650 a05dafa4a4630b4d4f777dc8aba12e7a 209 Pfam PF00156 Phosphoribosyl transferase domain 65 159 1.9E-15 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPSF3K_RS07650 a05dafa4a4630b4d4f777dc8aba12e7a 209 Gene3D G3DSA:3.40.50.2020 3 209 1.6E-36 T 29-03-2018 SPSF3K_RS07650 a05dafa4a4630b4d4f777dc8aba12e7a 209 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 178 3.2E-45 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS10620 e562906514e31646c8b5209359b9e4fb 485 PIRSF PIRSF000485 8 474 1.9E-173 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SPSF3K_RS10620 e562906514e31646c8b5209359b9e4fb 485 Gene3D G3DSA:3.60.20.10 12 254 1.1E-55 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SPSF3K_RS10620 e562906514e31646c8b5209359b9e4fb 485 Pfam PF00156 Phosphoribosyl transferase domain 278 384 1.6E-9 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPSF3K_RS10620 e562906514e31646c8b5209359b9e4fb 485 SUPERFAMILY SSF56235 12 254 6.35E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal SPSF3K_RS10620 e562906514e31646c8b5209359b9e4fb 485 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 457 45.226 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SPSF3K_RS10620 e562906514e31646c8b5209359b9e4fb 485 Pfam PF13537 Glutamine amidotransferase domain 91 210 9.1E-19 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain SPSF3K_RS10620 e562906514e31646c8b5209359b9e4fb 485 Gene3D G3DSA:3.40.50.2020 268 436 6.6E-33 T 29-03-2018 SPSF3K_RS10620 e562906514e31646c8b5209359b9e4fb 485 SUPERFAMILY SSF53271 248 465 9.57E-73 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS10620 e562906514e31646c8b5209359b9e4fb 485 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 458 5.8E-154 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 SPSF3K_RS04780 026afea9e662c87cb28404ac7e700bde 159 SUPERFAMILY SSF81333 88 156 6.15E-9 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPSF3K_RS04780 026afea9e662c87cb28404ac7e700bde 159 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 58 82 1.3E-6 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04780 026afea9e662c87cb28404ac7e700bde 159 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 133 156 1.3E-6 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04780 026afea9e662c87cb28404ac7e700bde 159 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 32 56 1.3E-6 T 29-03-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04780 026afea9e662c87cb28404ac7e700bde 159 Pfam PF00137 ATP synthase subunit C 97 154 5.4E-12 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPSF3K_RS04780 026afea9e662c87cb28404ac7e700bde 159 Pfam PF00137 ATP synthase subunit C 19 78 1.9E-13 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPSF3K_RS04780 026afea9e662c87cb28404ac7e700bde 159 SUPERFAMILY SSF81333 15 80 2.22E-10 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPSF3K_RS04780 026afea9e662c87cb28404ac7e700bde 159 Gene3D G3DSA:1.20.20.10 13 81 1.0E-12 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPSF3K_RS04780 026afea9e662c87cb28404ac7e700bde 159 Gene3D G3DSA:1.20.20.10 86 156 2.7E-12 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPSF3K_RS02730 741801f02a05ad4b40df4e5e91c58d65 434 Gene3D G3DSA:1.20.1170.10 33 394 1.2E-7 T 29-03-2018 SPSF3K_RS02730 741801f02a05ad4b40df4e5e91c58d65 434 Pfam PF01076 Plasmid recombination enzyme 1 195 1.4E-73 T 29-03-2018 IPR001668 Plasmid recombination enzyme GO:0003677|GO:0005727|GO:0006310 SPSF3K_RS08250 b631ccac8181213a9690145b8991b918 79 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 17 75 7.1E-20 T 29-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 SPSF3K_RS08250 b631ccac8181213a9690145b8991b918 79 Pfam PF00550 Phosphopantetheine attachment site 6 71 1.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SPSF3K_RS08250 b631ccac8181213a9690145b8991b918 79 Gene3D G3DSA:1.10.1200.10 1 79 3.6E-11 T 29-03-2018 SPSF3K_RS08250 b631ccac8181213a9690145b8991b918 79 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 77 46.401 T 29-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 SPSF3K_RS08250 b631ccac8181213a9690145b8991b918 79 SUPERFAMILY SSF47336 8 78 4.97E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SPSF3K_RS09115 d3c4311dee5278bc8967c92d47e3c947 1112 Gene3D G3DSA:3.80.10.10 251 429 1.4E-9 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SPSF3K_RS09115 d3c4311dee5278bc8967c92d47e3c947 1112 SUPERFAMILY SSF52058 286 391 1.46E-6 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SPSF3K_RS09115 d3c4311dee5278bc8967c92d47e3c947 1112 Pfam PF13306 Leucine rich repeats (6 copies) 536 630 7.4E-17 T 29-03-2018 IPR026906 Leucine rich repeat 5 SPSF3K_RS09115 d3c4311dee5278bc8967c92d47e3c947 1112 Pfam PF13306 Leucine rich repeats (6 copies) 292 408 4.2E-24 T 29-03-2018 IPR026906 Leucine rich repeat 5 SPSF3K_RS09115 d3c4311dee5278bc8967c92d47e3c947 1112 Gene3D G3DSA:3.80.10.10 482 826 1.3E-8 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SPSF3K_RS09115 d3c4311dee5278bc8967c92d47e3c947 1112 SUPERFAMILY SSF52058 303 373 1.36E-5 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SPSF3K_RS09115 d3c4311dee5278bc8967c92d47e3c947 1112 SUPERFAMILY SSF52058 532 711 1.36E-5 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like SPSF3K_RS08340 1f285da8cb3211549d7be85673549708 407 SUPERFAMILY SSF103473 8 395 3.27E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS08340 1f285da8cb3211549d7be85673549708 407 Gene3D G3DSA:1.20.1250.20 7 190 1.2E-29 T 29-03-2018 SPSF3K_RS08340 1f285da8cb3211549d7be85673549708 407 Gene3D G3DSA:1.20.1250.20 201 398 2.1E-27 T 29-03-2018 SPSF3K_RS08340 1f285da8cb3211549d7be85673549708 407 Pfam PF07690 Major Facilitator Superfamily 27 253 6.3E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS09930 37c82a416ecbb9c3a07273842b2cdf70 145 Pfam PF03965 Penicillinase repressor 4 117 2.1E-29 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SPSF3K_RS09930 37c82a416ecbb9c3a07273842b2cdf70 145 PIRSF PIRSF019455 1 129 4.8E-34 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SPSF3K_RS09930 37c82a416ecbb9c3a07273842b2cdf70 145 TIGRFAM TIGR02698 CopY_TcrY: copper transport repressor, CopY/TcrY family 3 130 8.5E-40 T 29-03-2018 IPR014071 Copper transport repressor CopY/TcrY SPSF3K_RS09930 37c82a416ecbb9c3a07273842b2cdf70 145 Gene3D G3DSA:1.10.10.10 5 68 4.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09930 37c82a416ecbb9c3a07273842b2cdf70 145 SUPERFAMILY SSF46785 1 118 3.08E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00630 1565cceac906910f3d8158941fb68b6c 202 SUPERFAMILY SSF50475 3 198 1.28E-32 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SPSF3K_RS00630 1565cceac906910f3d8158941fb68b6c 202 SMART SM00903 20 174 2.2E-7 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SPSF3K_RS00630 1565cceac906910f3d8158941fb68b6c 202 Gene3D G3DSA:2.30.110.10 3 200 8.2E-37 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SPSF3K_RS00630 1565cceac906910f3d8158941fb68b6c 202 Pfam PF01613 Flavin reductase like domain 23 167 2.5E-11 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 SUPERFAMILY SSF51261 481 630 1.44E-50 T 29-03-2018 IPR011055 Duplicated hybrid motif SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 549 561 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 Pfam PF02378 Phosphotransferase system, EIIC 109 399 1.1E-34 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 453 2.8E-184 T 29-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 Gene3D G3DSA:3.30.1360.60 4 80 2.4E-25 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 486 610 2.9E-47 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 Pfam PF00367 phosphotransferase system, EIIB 8 41 5.4E-14 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 487 607 1.6E-43 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 Gene3D G3DSA:2.70.70.10 473 632 4.6E-57 T 29-03-2018 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 SUPERFAMILY SSF55604 6 79 6.28E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS01690 ac1f68ea5fbf91283eb0ef0235f541bd 632 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 42.863 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 Pfam PF00318 Ribosomal protein S2 9 224 3.2E-96 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 SUPERFAMILY SSF52313 6 234 1.83E-95 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.0E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.0E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.0E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.0E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.0E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.0E-41 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 Gene3D G3DSA:3.40.50.10490 5 254 2.2E-98 T 29-03-2018 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 2.8E-105 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00595 dbb079804fe8b408681166b7d6723484 255 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS07350 b97bb96b913cf7a91f73601b42c78e62 129 Pfam PF06896 Phage tail assembly chaperone proteins, TAC 6 112 3.0E-12 T 29-03-2018 IPR009681 Phage tail assembly chaperone protein, Siphoviridae SPSF3K_RS04530 bb430d1aad8dbbd06dd49ff480ca56a6 211 Gene3D G3DSA:3.60.15.10 1 211 5.5E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS04530 bb430d1aad8dbbd06dd49ff480ca56a6 211 SUPERFAMILY SSF56281 1 211 1.11E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS04530 bb430d1aad8dbbd06dd49ff480ca56a6 211 Pfam PF00753 Metallo-beta-lactamase superfamily 13 194 5.0E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS04530 bb430d1aad8dbbd06dd49ff480ca56a6 211 SMART SM00849 12 194 1.8E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS10425 1ae7cb4b4d0b4a3c9f90007c15cae007 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 2.5E-37 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P SPSF3K_RS10425 1ae7cb4b4d0b4a3c9f90007c15cae007 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 1.3E-53 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10425 1ae7cb4b4d0b4a3c9f90007c15cae007 146 SUPERFAMILY SSF52080 4 144 8.9E-48 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P SPSF3K_RS10425 1ae7cb4b4d0b4a3c9f90007c15cae007 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 21.634 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 SPSF3K_RS10425 1ae7cb4b4d0b4a3c9f90007c15cae007 146 Gene3D G3DSA:3.100.10.10 41 146 1.0E-31 T 29-03-2018 SPSF3K_RS10425 1ae7cb4b4d0b4a3c9f90007c15cae007 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS06810 22740adcb0c666096f156b3e595cc8ef 221 Gene3D G3DSA:1.10.10.10 124 221 3.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06810 22740adcb0c666096f156b3e595cc8ef 221 SUPERFAMILY SSF46894 122 220 1.11E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPSF3K_RS06810 22740adcb0c666096f156b3e595cc8ef 221 SMART SM00448 5 114 3.3E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS06810 22740adcb0c666096f156b3e595cc8ef 221 SUPERFAMILY SSF52172 5 134 1.85E-29 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS06810 22740adcb0c666096f156b3e595cc8ef 221 Gene3D G3DSA:3.40.50.2300 2 123 3.1E-25 T 29-03-2018 SPSF3K_RS06810 22740adcb0c666096f156b3e595cc8ef 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 1.5E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS06810 22740adcb0c666096f156b3e595cc8ef 221 Pfam PF00072 Response regulator receiver domain 7 114 7.3E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS06810 22740adcb0c666096f156b3e595cc8ef 221 SMART SM00862 146 220 1.5E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS00565 91798d10d9a8249d935e936b1cc6a248 94 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 82 1.4E-12 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS00565 91798d10d9a8249d935e936b1cc6a248 94 SUPERFAMILY SSF52794 1 89 8.2E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS00565 91798d10d9a8249d935e936b1cc6a248 94 Gene3D G3DSA:3.40.50.2300 1 92 3.8E-15 T 29-03-2018 SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 Pfam PF07702 UTRA domain 95 224 8.0E-28 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 SMART SM00866 91 230 2.2E-23 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 SMART SM00345 7 66 5.8E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 Gene3D G3DSA:3.40.1410.10 79 225 8.5E-28 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 1.0E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 Gene3D G3DSA:1.10.10.10 1 68 6.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 SUPERFAMILY SSF46785 2 70 3.41E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 SUPERFAMILY SSF64288 54 228 7.54E-35 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 2.6E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS06465 59c0034ccd5a86e7f8bc16d0b9b5c366 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 2.6E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS07915 475585e27dbc7ceaa79475ff86794289 152 Gene3D G3DSA:2.170.150.20 1 146 4.0E-49 T 29-03-2018 SPSF3K_RS07915 475585e27dbc7ceaa79475ff86794289 152 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 138 1.0E-55 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SPSF3K_RS07915 475585e27dbc7ceaa79475ff86794289 152 SUPERFAMILY SSF51316 5 144 2.46E-53 T 29-03-2018 IPR011057 Mss4-like SPSF3K_RS07915 475585e27dbc7ceaa79475ff86794289 152 Pfam PF01641 SelR domain 12 129 8.0E-45 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 SPSF3K_RS08120 290c259f41c7b314ee5b9c238abdf7de 227 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 21 220 2.3E-70 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 SPSF3K_RS08120 290c259f41c7b314ee5b9c238abdf7de 227 SUPERFAMILY SSF53335 5 138 7.37E-11 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS08120 290c259f41c7b314ee5b9c238abdf7de 227 PIRSF PIRSF018637 2 226 5.7E-70 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 SPSF3K_RS08120 290c259f41c7b314ee5b9c238abdf7de 227 Gene3D G3DSA:3.40.50.150 1 165 1.0E-20 T 29-03-2018 SPSF3K_RS01845 7d7db9e958ab98dadb525ce3a3609f21 237 Pfam PF08241 Methyltransferase domain 37 127 5.3E-15 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SPSF3K_RS01845 7d7db9e958ab98dadb525ce3a3609f21 237 SUPERFAMILY SSF53335 27 176 8.75E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS01845 7d7db9e958ab98dadb525ce3a3609f21 237 Gene3D G3DSA:3.40.50.150 5 227 6.2E-21 T 29-03-2018 SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 SUPERFAMILY SSF53633 1 288 1.83E-69 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 6.6E-88 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 Pfam PF00696 Amino acid kinase family 2 276 3.9E-42 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 Gene3D G3DSA:3.40.1160.10 1 281 4.7E-56 T 29-03-2018 SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 SUPERFAMILY SSF55021 371 448 4.32E-22 T 29-03-2018 SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 Pfam PF13840 ACT domain 381 444 4.0E-12 T 29-03-2018 IPR027795 GATS-like ACT domain SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 PIRSF PIRSF000726 1 449 5.7E-88 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 SUPERFAMILY SSF55021 297 360 2.18E-9 T 29-03-2018 SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 Gene3D G3DSA:3.30.70.260 371 449 1.2E-21 T 29-03-2018 SPSF3K_RS02875 9bb7197c44e933ca457325bd3fe7ddb7 449 Gene3D G3DSA:3.30.70.260 282 370 6.2E-17 T 29-03-2018 SPSF3K_RS07675 b53db325a8480472e745b34197a83646 252 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 11 165 3.5E-24 T 29-03-2018 IPR014903 Protein of unknown function DUF1796 SPSF3K_RS00110 fe21d479db4e4508bba8aefaaa74835d 210 Gene3D G3DSA:1.10.150.240 27 71 3.2E-17 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SPSF3K_RS00110 fe21d479db4e4508bba8aefaaa74835d 210 Gene3D G3DSA:3.40.50.1000 1 26 0.19 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS00110 fe21d479db4e4508bba8aefaaa74835d 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 179 9.5E-38 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS00110 fe21d479db4e4508bba8aefaaa74835d 210 Gene3D G3DSA:3.40.50.1000 72 210 4.2E-23 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS00110 fe21d479db4e4508bba8aefaaa74835d 210 SUPERFAMILY SSF56784 1 209 1.27E-50 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 393 5.7E-159 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 Gene3D G3DSA:3.40.50.620 4 156 1.0E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 Gene3D G3DSA:1.20.5.470 361 394 1.8E-9 T 29-03-2018 SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 SUPERFAMILY SSF69864 169 394 7.85E-91 T 29-03-2018 SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 Pfam PF00764 Arginosuccinate synthase 7 389 6.4E-171 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 115 126 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 SUPERFAMILY SSF52402 3 164 1.52E-44 T 29-03-2018 SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 395 53.571 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS01015 5e87b8dae0b4be81b894036b93a2aad0 400 Gene3D G3DSA:3.90.1260.10 157 351 2.1E-82 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS01265 c4f15ab5341172744df5c88ba322240d 236 Gene3D G3DSA:3.30.420.40 1 144 2.6E-36 T 29-03-2018 SPSF3K_RS01265 c4f15ab5341172744df5c88ba322240d 236 SUPERFAMILY SSF53067 7 108 1.64E-26 T 29-03-2018 SPSF3K_RS01265 c4f15ab5341172744df5c88ba322240d 236 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 9 212 2.1E-52 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 SPSF3K_RS01265 c4f15ab5341172744df5c88ba322240d 236 Pfam PF00814 Glycoprotease family 37 170 8.3E-29 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPSF3K_RS01265 c4f15ab5341172744df5c88ba322240d 236 SUPERFAMILY SSF53067 115 210 2.46E-7 T 29-03-2018 SPSF3K_RS01465 b0ac2924447f139fbc672024f81b2b0d 463 Pfam PF00682 HMGL-like 3 268 3.9E-50 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 SPSF3K_RS01465 b0ac2924447f139fbc672024f81b2b0d 463 SUPERFAMILY SSF89000 299 451 1.22E-50 T 29-03-2018 SPSF3K_RS01465 b0ac2924447f139fbc672024f81b2b0d 463 Gene3D G3DSA:1.10.10.60 401 446 1.2E-12 T 29-03-2018 SPSF3K_RS01465 b0ac2924447f139fbc672024f81b2b0d 463 Gene3D G3DSA:3.20.20.70 1 277 4.3E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS01465 b0ac2924447f139fbc672024f81b2b0d 463 SUPERFAMILY SSF51569 2 277 2.75E-87 T 29-03-2018 SPSF3K_RS01465 b0ac2924447f139fbc672024f81b2b0d 463 Pfam PF02436 Conserved carboxylase domain 296 445 1.9E-49 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 SPSF3K_RS09780 83b5e8ef048a2dd157c6b7f6ddced0e6 335 ProSitePatterns PS01348 MraY family signature 2. 167 178 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SPSF3K_RS09780 83b5e8ef048a2dd157c6b7f6ddced0e6 335 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 5.3E-5 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SPSF3K_RS09780 83b5e8ef048a2dd157c6b7f6ddced0e6 335 Pfam PF00953 Glycosyl transferase family 4 84 247 5.1E-37 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SPSF3K_RS09780 83b5e8ef048a2dd157c6b7f6ddced0e6 335 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 331 3.4E-74 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SPSF3K_RS09780 83b5e8ef048a2dd157c6b7f6ddced0e6 335 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 334 21.295 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SPSF3K_RS03895 97f8b5e0e302e75988f9f6f0e9d625a6 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 37 161 5.6E-40 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SPSF3K_RS03895 97f8b5e0e302e75988f9f6f0e9d625a6 165 Gene3D G3DSA:3.40.390.30 1 165 1.7E-42 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 SPSF3K_RS03895 97f8b5e0e302e75988f9f6f0e9d625a6 165 Pfam PF02130 Uncharacterized protein family UPF0054 13 159 1.5E-40 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SPSF3K_RS03895 97f8b5e0e302e75988f9f6f0e9d625a6 165 SUPERFAMILY SSF55486 2 164 1.15E-39 T 29-03-2018 SPSF3K_RS03895 97f8b5e0e302e75988f9f6f0e9d625a6 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 130 140 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site SPSF3K_RS03895 97f8b5e0e302e75988f9f6f0e9d625a6 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 164 21.606 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SPSF3K_RS00090 2be7b1b81ec687867b46136d4ee4a36a 279 SUPERFAMILY SSF52540 4 232 1.52E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00090 2be7b1b81ec687867b46136d4ee4a36a 279 Gene3D G3DSA:3.40.50.300 1 246 2.6E-67 T 29-03-2018 SPSF3K_RS00090 2be7b1b81ec687867b46136d4ee4a36a 279 Pfam PF00005 ABC transporter 23 169 6.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00090 2be7b1b81ec687867b46136d4ee4a36a 279 SMART SM00382 32 217 1.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00090 2be7b1b81ec687867b46136d4ee4a36a 279 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 5 273 4.4E-114 T 29-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 SPSF3K_RS00090 2be7b1b81ec687867b46136d4ee4a36a 279 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS00605 0e97e4e2986b75543159143997d0d92e 186 Gene3D G3DSA:3.30.1020.10 151 182 2.2E-6 T 29-03-2018 SPSF3K_RS00605 0e97e4e2986b75543159143997d0d92e 186 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 186 7.1E-101 T 29-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SPSF3K_RS00605 0e97e4e2986b75543159143997d0d92e 186 PIRSF PIRSF000239 1 186 1.3E-51 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SPSF3K_RS00605 0e97e4e2986b75543159143997d0d92e 186 Gene3D G3DSA:3.40.30.10 1 150 2.6E-31 T 29-03-2018 SPSF3K_RS00605 0e97e4e2986b75543159143997d0d92e 186 SUPERFAMILY SSF52833 1 186 1.88E-54 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS00605 0e97e4e2986b75543159143997d0d92e 186 Pfam PF00578 AhpC/TSA family 4 132 8.5E-34 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SPSF3K_RS00605 0e97e4e2986b75543159143997d0d92e 186 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 181 3.1E-5 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 SPSF3K_RS07095 5357a601be3c210de15e985796041166 134 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 36.464 T 29-03-2018 IPR023731 Regulatory protein Spx GO:0045892 SPSF3K_RS07095 5357a601be3c210de15e985796041166 134 SUPERFAMILY SSF52833 1 125 8.67E-39 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS07095 5357a601be3c210de15e985796041166 134 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 3.5E-35 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR SPSF3K_RS07095 5357a601be3c210de15e985796041166 134 Gene3D G3DSA:3.40.30.10 1 131 7.5E-38 T 29-03-2018 SPSF3K_RS07095 5357a601be3c210de15e985796041166 134 Pfam PF03960 ArsC family 18 113 4.3E-25 T 29-03-2018 IPR006660 Arsenate reductase-like SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 SUPERFAMILY SSF57783 413 446 1.7E-6 T 29-03-2018 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 Gene3D G3DSA:2.70.20.10 137 256 5.0E-23 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 SMART SM00437 58 336 5.2E-108 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 Gene3D G3DSA:1.10.460.10 12 130 7.1E-8 T 29-03-2018 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 Pfam PF01131 DNA topoisomerase 6 372 5.1E-77 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 SUPERFAMILY SSF56712 5 386 4.19E-91 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 Gene3D G3DSA:3.30.65.10 409 455 1.7E-12 T 29-03-2018 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 109 5.9E-9 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 181 197 5.9E-9 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 299 313 5.9E-9 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 411 440 3.6E-11 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 Gene3D G3DSA:1.10.460.10 257 408 5.9E-26 T 29-03-2018 SPSF3K_RS05865 a5a3652289e6d13ea2cb7e7d724c8c5a 495 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 95 109 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SPSF3K_RS02340 2aeac1ff33f3315ab0ce59fb7c6f2ae8 190 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 11 171 9.0E-41 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SPSF3K_RS02340 2aeac1ff33f3315ab0ce59fb7c6f2ae8 190 Gene3D G3DSA:3.10.300.10 1 182 8.0E-47 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SPSF3K_RS02340 2aeac1ff33f3315ab0ce59fb7c6f2ae8 190 SUPERFAMILY SSF50486 7 180 6.91E-48 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SPSF3K_RS02340 2aeac1ff33f3315ab0ce59fb7c6f2ae8 190 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 3 175 23.607 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SPSF3K_RS02340 2aeac1ff33f3315ab0ce59fb7c6f2ae8 190 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 10 175 2.1E-40 T 29-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 SPSF3K_RS09915 652fea9c42f160b699e8b49e1b699733 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 237 5.1E-30 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS09915 652fea9c42f160b699e8b49e1b699733 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 264 3.2E-66 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09915 652fea9c42f160b699e8b49e1b699733 271 SUPERFAMILY SSF56784 1 269 2.21E-70 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS09915 652fea9c42f160b699e8b49e1b699733 271 ProSitePatterns PS01229 Hypothetical cof family signature 2. 218 240 - T 29-03-2018 SPSF3K_RS09915 652fea9c42f160b699e8b49e1b699733 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 264 2.1E-62 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS09915 652fea9c42f160b699e8b49e1b699733 271 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 29-03-2018 SPSF3K_RS09915 652fea9c42f160b699e8b49e1b699733 271 Gene3D G3DSA:3.40.50.1000 1 271 4.4E-40 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 SUPERFAMILY SSF56024 498 677 1.7E-56 T 29-03-2018 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 SUPERFAMILY SSF140356 4 108 9.68E-33 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 Gene3D G3DSA:3.30.870.10 317 489 2.9E-17 T 29-03-2018 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 PIRSF PIRSF015589 3 691 1.0E-205 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 Gene3D G3DSA:3.30.1840.10 111 301 1.7E-42 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 Gene3D G3DSA:3.30.870.10 496 682 1.1E-31 T 29-03-2018 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 SUPERFAMILY SSF56024 318 487 1.02E-44 T 29-03-2018 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 Gene3D G3DSA:1.20.58.310 8 110 6.4E-33 T 29-03-2018 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 Pfam PF02503 Polyphosphate kinase middle domain 120 318 4.1E-45 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 Pfam PF13089 Polyphosphate kinase N-terminal domain 7 110 1.8E-33 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 Pfam PF13090 Polyphosphate kinase C-terminal domain 327 672 1.5E-129 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 SUPERFAMILY SSF143724 109 300 4.71E-38 T 29-03-2018 SPSF3K_RS02610 0dd6f27ad7c6d831030c448bc958dc66 708 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 6 673 1.2E-209 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 SMART SM00562 1 143 8.3E-57 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 117 125 - T 29-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 141 30.085 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 PRINTS PR01243 Nucleoside diphosphate kinase signature 117 136 1.4E-29 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 1.4E-29 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 1.4E-29 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 1.4E-29 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 Gene3D G3DSA:3.30.70.141 1 144 1.8E-48 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 Pfam PF00334 Nucleoside diphosphate kinase 2 140 1.7E-45 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS07935 bc1e695e65d07b41ad7fe53aca0ef865 144 SUPERFAMILY SSF54919 1 141 4.19E-49 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS08635 b02be70caeedfe8e0e568ebb465daf9e 381 SUPERFAMILY SSF103473 8 380 1.57E-46 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS08635 b02be70caeedfe8e0e568ebb465daf9e 381 Gene3D G3DSA:1.20.1250.20 195 381 6.8E-23 T 29-03-2018 SPSF3K_RS08635 b02be70caeedfe8e0e568ebb465daf9e 381 Pfam PF07690 Major Facilitator Superfamily 15 262 2.8E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS08635 b02be70caeedfe8e0e568ebb465daf9e 381 Gene3D G3DSA:1.20.1250.20 6 191 2.4E-19 T 29-03-2018 SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 4.4E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 Gene3D G3DSA:1.10.10.10 1 66 1.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 SMART SM00345 8 67 2.7E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 SUPERFAMILY SSF64288 55 230 7.38E-46 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 SUPERFAMILY SSF46785 3 71 8.24E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 Gene3D G3DSA:3.40.1410.10 67 232 6.9E-39 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 9.7E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 9.7E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 SMART SM00866 88 226 1.6E-36 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS06590 6128e503a4472dc7c59998f1a388a031 232 Pfam PF07702 UTRA domain 88 226 8.8E-36 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS07980 6ac81981e104a6fdcead451e90df4b70 447 Pfam PF08245 Mur ligase middle domain 53 281 7.6E-12 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS07980 6ac81981e104a6fdcead451e90df4b70 447 SUPERFAMILY SSF53623 39 190 6.41E-34 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS07980 6ac81981e104a6fdcead451e90df4b70 447 SUPERFAMILY SSF53623 238 296 6.41E-34 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS07980 6ac81981e104a6fdcead451e90df4b70 447 Gene3D G3DSA:3.40.1190.10 45 304 1.2E-40 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS07980 6ac81981e104a6fdcead451e90df4b70 447 Pfam PF08353 Domain of unknown function (DUF1727) 319 429 1.6E-30 T 29-03-2018 IPR013564 Domain of unknown function DUF1727 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 Pfam PF00448 SRP54-type protein, GTPase domain 334 533 1.4E-76 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 261 533 9.8E-109 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 Gene3D G3DSA:3.40.50.300 330 535 1.3E-37 T 29-03-2018 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 SUPERFAMILY SSF52540 334 533 3.66E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 SMART SM00382 332 524 1.1E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 260 534 61.364 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 Pfam PF02881 SRP54-type protein, helical bundle domain 248 313 4.6E-13 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 507 520 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 Gene3D G3DSA:1.20.120.140 233 322 1.2E-18 T 29-03-2018 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 SUPERFAMILY SSF47364 233 310 6.02E-19 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 SMART SM00962 333 534 8.6E-113 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS04180 a5356cad5182b88c1ca528f6be18c108 537 SMART SM00963 236 317 7.7E-22 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 Gene3D G3DSA:3.40.190.10 89 172 7.6E-13 T 29-03-2018 SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 Gene3D G3DSA:1.10.10.10 1 83 2.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 Pfam PF03466 LysR substrate binding domain 91 299 7.8E-32 T 29-03-2018 IPR005119 LysR, substrate-binding SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.8E-13 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 SUPERFAMILY SSF46785 1 110 1.22E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 SUPERFAMILY SSF53850 91 300 3.44E-28 T 29-03-2018 SPSF3K_RS01400 a90865c3a01bdc17000653fd3206b94e 301 Gene3D G3DSA:3.40.190.10 173 273 2.5E-11 T 29-03-2018 SPSF3K_RS01315 6b2589a33be46b32c6c8c2cf00dca27d 347 Pfam PF03812 2-keto-3-deoxygluconate permease 4 315 5.9E-102 T 29-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 SPSF3K_RS01315 6b2589a33be46b32c6c8c2cf00dca27d 347 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 14 318 3.0E-54 T 29-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 SPSF3K_RS10075 eeb97ef50c0627f65f2aabd373be0ea9 140 SUPERFAMILY SSF54637 5 138 3.18E-47 T 29-03-2018 IPR029069 HotDog domain SPSF3K_RS10075 eeb97ef50c0627f65f2aabd373be0ea9 140 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 140 34.086 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SPSF3K_RS10075 eeb97ef50c0627f65f2aabd373be0ea9 140 Pfam PF07977 FabA-like domain 11 131 1.5E-35 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SPSF3K_RS10075 eeb97ef50c0627f65f2aabd373be0ea9 140 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 5.0E-61 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 SPSF3K_RS10075 eeb97ef50c0627f65f2aabd373be0ea9 140 Gene3D G3DSA:3.10.129.10 1 140 4.0E-53 T 29-03-2018 SPSF3K_RS02475 9a8e1387380780c31b716ad43f6a4906 151 Gene3D G3DSA:3.40.50.360 4 148 8.6E-17 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS02475 9a8e1387380780c31b716ad43f6a4906 151 PIRSF PIRSF005087 2 151 2.3E-39 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI SPSF3K_RS02475 9a8e1387380780c31b716ad43f6a4906 151 Pfam PF07972 NrdI Flavodoxin like 6 139 3.0E-39 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI SPSF3K_RS02475 9a8e1387380780c31b716ad43f6a4906 151 SUPERFAMILY SSF52218 1 142 3.94E-19 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 Gene3D G3DSA:3.30.9.10 208 350 9.3E-42 T 29-03-2018 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 Gene3D G3DSA:3.30.9.10 99 207 9.9E-6 T 29-03-2018 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 SUPERFAMILY SSF54373 253 349 3.4E-12 T 29-03-2018 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 466 587 1.8E-16 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 6.8E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 6.8E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 6.8E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 425 437 6.8E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 6.8E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 349 6.8E-30 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 Pfam PF01266 FAD dependent oxidoreductase 21 352 2.3E-55 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 Gene3D G3DSA:3.50.50.60 4 90 3.3E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 SUPERFAMILY SSF51905 160 247 3.24E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS09850 5ef7b82f7942af6d75dcaa5d798514b2 609 SUPERFAMILY SSF51905 9 124 3.24E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01520 5ac7c061f9bb81f044283e7c2356147c 66 SUPERFAMILY SSF47413 6 65 9.85E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS01520 5ac7c061f9bb81f044283e7c2356147c 66 Pfam PF01381 Helix-turn-helix 6 63 9.2E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS01520 5ac7c061f9bb81f044283e7c2356147c 66 SMART SM00530 5 63 4.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS01520 5ac7c061f9bb81f044283e7c2356147c 66 Gene3D G3DSA:1.10.260.40 3 65 6.5E-16 T 29-03-2018 SPSF3K_RS10520 15415d9e2981dd797144fd761e97a18d 208 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 204 37.529 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10520 15415d9e2981dd797144fd761e97a18d 208 ProSitePatterns PS00474 Ribosomal protein L3 signature. 100 123 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site SPSF3K_RS10520 15415d9e2981dd797144fd761e97a18d 208 SUPERFAMILY SSF50447 1 205 7.77E-78 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS10520 15415d9e2981dd797144fd761e97a18d 208 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 201 9.7E-82 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10520 15415d9e2981dd797144fd761e97a18d 208 Pfam PF00297 Ribosomal protein L3 97 177 2.0E-14 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10520 15415d9e2981dd797144fd761e97a18d 208 Gene3D G3DSA:4.10.960.10 60 162 9.4E-32 T 29-03-2018 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 SUPERFAMILY SSF46689 188 239 1.61E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 SMART SM00342 205 288 4.3E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 Pfam PF02311 AraC-like ligand binding domain 37 167 7.0E-16 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 Gene3D G3DSA:1.10.10.60 242 299 1.6E-13 T 29-03-2018 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 Pfam PF12833 Helix-turn-helix domain 211 289 2.8E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 SUPERFAMILY SSF46689 241 291 3.26E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 Gene3D G3DSA:2.60.120.280 6 176 1.8E-14 T 29-03-2018 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 Gene3D G3DSA:1.10.10.60 185 241 1.5E-15 T 29-03-2018 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 SUPERFAMILY SSF51215 37 170 7.72E-12 T 29-03-2018 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 257 272 2.5E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SPSF3K_RS06180 6b16e458d1e0d1dc4053cf5028f92b35 308 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 272 288 2.5E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SPSF3K_RS09600 86b7cf769a1867a59c5b4c7722c6af17 434 Pfam PF00271 Helicase conserved C-terminal domain 289 397 4.0E-14 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS09600 86b7cf769a1867a59c5b4c7722c6af17 434 Gene3D G3DSA:3.40.50.300 276 434 6.1E-19 T 29-03-2018 SPSF3K_RS09600 86b7cf769a1867a59c5b4c7722c6af17 434 Pfam PF04851 Type III restriction enzyme, res subunit 95 207 2.1E-5 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SPSF3K_RS09600 86b7cf769a1867a59c5b4c7722c6af17 434 SUPERFAMILY SSF52540 111 405 8.75E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09600 86b7cf769a1867a59c5b4c7722c6af17 434 Gene3D G3DSA:3.40.50.300 87 261 1.5E-19 T 29-03-2018 SPSF3K_RS09600 86b7cf769a1867a59c5b4c7722c6af17 434 SMART SM00487 92 275 7.4E-13 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS09600 86b7cf769a1867a59c5b4c7722c6af17 434 SMART SM00490 316 399 3.7E-13 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS06850 d740c47c5004667787a2e89a5a581b46 352 Pfam PF13303 Phosphotransferase system, EIIC 15 350 3.8E-87 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS03635 2800166ecdb8f934ffa5f016156aa144 218 Pfam PF02223 Thymidylate kinase 16 205 5.0E-47 T 29-03-2018 SPSF3K_RS03635 2800166ecdb8f934ffa5f016156aa144 218 ProSitePatterns PS01331 Thymidylate kinase signature. 102 114 - T 29-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SPSF3K_RS03635 2800166ecdb8f934ffa5f016156aa144 218 Hamap MF_00165 Thymidylate kinase [tmk]. 12 216 29.46 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SPSF3K_RS03635 2800166ecdb8f934ffa5f016156aa144 218 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 10 205 3.0E-54 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SPSF3K_RS03635 2800166ecdb8f934ffa5f016156aa144 218 Gene3D G3DSA:3.40.50.300 8 217 6.2E-53 T 29-03-2018 SPSF3K_RS03635 2800166ecdb8f934ffa5f016156aa144 218 SUPERFAMILY SSF52540 10 214 5.28E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 Pfam PF00106 short chain dehydrogenase 5 186 3.8E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 Gene3D G3DSA:3.40.50.720 1 254 2.7E-46 T 29-03-2018 SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.1E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 5.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 5.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 5.4E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08150 dfd3d28e6a302b8235e0522f2a236771 254 SUPERFAMILY SSF51735 1 250 2.16E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS10635 3679284e468f4b699959844f3afcd64f 80 Gene3D G3DSA:1.10.1200.10 4 80 9.7E-20 T 29-03-2018 SPSF3K_RS10635 3679284e468f4b699959844f3afcd64f 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 36 78 6.0E-8 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SPSF3K_RS10635 3679284e468f4b699959844f3afcd64f 80 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 16.659 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SPSF3K_RS10635 3679284e468f4b699959844f3afcd64f 80 Pfam PF00550 Phosphopantetheine attachment site 8 75 3.4E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SPSF3K_RS10635 3679284e468f4b699959844f3afcd64f 80 SUPERFAMILY SSF47336 1 79 2.75E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 Gene3D G3DSA:3.40.50.720 222 406 1.2E-45 T 29-03-2018 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 PIRSF PIRSF500134 360 411 0.31 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 PIRSF PIRSF500134 2 378 1.2E-119 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 323 399 7.6E-8 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 Gene3D G3DSA:1.20.5.100 201 221 2.1E-14 T 29-03-2018 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 400 7.1E-95 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 PIRSF PIRSF000124 2 411 2.2E-131 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 169 5.0E-33 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 288 1.1E-26 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 SUPERFAMILY SSF51735 2 201 1.94E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 SMART SM00984 322 410 3.8E-12 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 Gene3D G3DSA:3.40.50.720 1 200 1.0E-50 T 29-03-2018 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 SUPERFAMILY SSF48179 198 294 8.84E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPSF3K_RS07665 2b6c1a829b34aeae5adec5346b232085 411 SUPERFAMILY SSF52413 317 411 8.5E-25 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 SPSF3K_RS04495 6ed7155a09f16b2ee5808a3f3f74d849 294 TIGRFAM TIGR03729 acc_ester: putative phosphoesterase 3 227 1.1E-75 T 29-03-2018 IPR022302 Phosphoesterase, putative SPSF3K_RS04495 6ed7155a09f16b2ee5808a3f3f74d849 294 Gene3D G3DSA:3.60.21.10 2 288 3.8E-18 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS04495 6ed7155a09f16b2ee5808a3f3f74d849 294 SUPERFAMILY SSF56300 142 234 1.12E-18 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS04495 6ed7155a09f16b2ee5808a3f3f74d849 294 SUPERFAMILY SSF56300 3 110 1.12E-18 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS04495 6ed7155a09f16b2ee5808a3f3f74d849 294 Pfam PF00149 Calcineurin-like phosphoesterase 3 208 4.3E-8 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 SMART SM00493 272 343 2.9E-16 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 Pfam PF01807 CHC2 zinc finger 13 106 1.2E-35 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 SUPERFAMILY SSF56731 123 435 2.62E-90 T 29-03-2018 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 Gene3D G3DSA:3.40.1360.20 268 382 6.8E-33 T 29-03-2018 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 SMART SM00400 43 97 1.7E-31 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 Pfam PF13155 Toprim-like 275 358 2.7E-17 T 29-03-2018 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 Pfam PF08275 DNA primase catalytic core, N-terminal domain 135 265 2.3E-34 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 PIRSF PIRSF002811 10 603 2.5E-167 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 Gene3D G3DSA:3.90.980.10 116 253 1.5E-37 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 TIGRFAM TIGR01391 dnaG: DNA primase 12 426 2.0E-134 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 SUPERFAMILY SSF57783 12 105 1.65E-32 T 29-03-2018 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 Gene3D G3DSA:3.90.580.10 9 109 6.5E-31 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SPSF3K_RS05010 b48e3afbd6891d238f3b29c5beaf5321 603 Hamap MF_00974 DNA primase [dnaG]. 11 593 26.353 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SPSF3K_RS02480 ce77aaaead683af0f7bb7ee9134fb39f 45 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 11 43 2.3E-8 T 29-03-2018 SPSF3K_RS02480 ce77aaaead683af0f7bb7ee9134fb39f 45 Pfam PF00746 LPXTG cell wall anchor motif 7 44 1.5E-5 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor SPSF3K_RS11025 16fd5eb458eaabe4baad3d8170df122a 441 Pfam PF01051 Initiator Replication protein 22 259 2.0E-52 T 29-03-2018 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 SPSF3K_RS11025 16fd5eb458eaabe4baad3d8170df122a 441 SUPERFAMILY SSF46785 147 262 9.11E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS11025 16fd5eb458eaabe4baad3d8170df122a 441 Gene3D G3DSA:1.10.10.10 8 157 2.9E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS11025 16fd5eb458eaabe4baad3d8170df122a 441 SUPERFAMILY SSF46785 20 146 7.62E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS11025 16fd5eb458eaabe4baad3d8170df122a 441 Gene3D G3DSA:1.10.10.10 158 268 2.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS11025 16fd5eb458eaabe4baad3d8170df122a 441 Pfam PF06430 Lactococcus lactis RepB C-terminus 264 385 1.1E-35 T 29-03-2018 IPR010931 Lactococcus lactis RepB, C-terminal SPSF3K_RS10945 16fd5eb458eaabe4baad3d8170df122a 441 Pfam PF01051 Initiator Replication protein 22 259 2.0E-52 T 29-03-2018 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 SPSF3K_RS10945 16fd5eb458eaabe4baad3d8170df122a 441 SUPERFAMILY SSF46785 147 262 9.11E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10945 16fd5eb458eaabe4baad3d8170df122a 441 Gene3D G3DSA:1.10.10.10 8 157 2.9E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10945 16fd5eb458eaabe4baad3d8170df122a 441 SUPERFAMILY SSF46785 20 146 7.62E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10945 16fd5eb458eaabe4baad3d8170df122a 441 Gene3D G3DSA:1.10.10.10 158 268 2.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10945 16fd5eb458eaabe4baad3d8170df122a 441 Pfam PF06430 Lactococcus lactis RepB C-terminus 264 385 1.1E-35 T 29-03-2018 IPR010931 Lactococcus lactis RepB, C-terminal SPSF3K_RS02415 946def18bb08962e6706ac9d39234454 67 PIRSF PIRSF002599 1 67 6.9E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 SPSF3K_RS02415 946def18bb08962e6706ac9d39234454 67 PRINTS PR00050 Cold shock protein signature 24 33 4.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPSF3K_RS02415 946def18bb08962e6706ac9d39234454 67 PRINTS PR00050 Cold shock protein signature 4 19 4.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPSF3K_RS02415 946def18bb08962e6706ac9d39234454 67 PRINTS PR00050 Cold shock protein signature 39 57 4.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPSF3K_RS02415 946def18bb08962e6706ac9d39234454 67 SMART SM00357 3 66 1.3E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SPSF3K_RS02415 946def18bb08962e6706ac9d39234454 67 SUPERFAMILY SSF50249 1 65 7.05E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS02415 946def18bb08962e6706ac9d39234454 67 Gene3D G3DSA:2.40.50.140 1 66 3.0E-28 T 29-03-2018 SPSF3K_RS02415 946def18bb08962e6706ac9d39234454 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 9.0E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPSF3K_RS02415 946def18bb08962e6706ac9d39234454 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 SUPERFAMILY SSF54637 323 422 3.74E-10 T 29-03-2018 IPR029069 HotDog domain SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 58 5.8E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 Pfam PF03061 Thioesterase superfamily 368 415 1.2E-4 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 Gene3D G3DSA:3.10.580.10 182 309 9.0E-25 T 29-03-2018 SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 Gene3D G3DSA:1.10.10.10 4 68 7.0E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 SUPERFAMILY SSF54631 184 314 5.49E-27 T 29-03-2018 SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 SUPERFAMILY SSF75138 71 182 5.1E-27 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 Pfam PF07085 DRTGG domain 75 177 4.7E-28 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 Gene3D G3DSA:3.40.1390.20 69 181 3.8E-24 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 SUPERFAMILY SSF46785 3 65 3.67E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 Gene3D G3DSA:3.10.129.10 310 425 3.1E-10 T 29-03-2018 SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 Pfam PF00571 CBS domain 202 243 2.3E-4 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS08465 983b4cac9fe31b2c9958fe0ed2fc05b7 427 Pfam PF00571 CBS domain 251 304 1.6E-8 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS08725 d49172d0fb0a933411b7e8e4e71a6060 185 TIGRFAM TIGR04518 ECF_S_folT_fam: ECF transporter S component, folate family 12 174 5.5E-31 T 29-03-2018 IPR030949 ECF transporter S component, folate family SPSF3K_RS08725 d49172d0fb0a933411b7e8e4e71a6060 185 Pfam PF07155 ECF-type riboflavin transporter, S component 11 175 4.8E-11 T 29-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 SPSF3K_RS06020 cd00170f0d1f1e3a1de5a35b86c6a8ec 82 Pfam PF11372 Domain of unknown function (DUF3173) 2 73 9.3E-25 T 29-03-2018 IPR021512 Protein of unknown function DUF3173 SPSF3K_RS01070 c4dd6eb838103769322f22b07ef7d693 234 SUPERFAMILY SSF51366 15 232 1.06E-53 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SPSF3K_RS01070 c4dd6eb838103769322f22b07ef7d693 234 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 38 233 1.6E-83 T 29-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 SPSF3K_RS01070 c4dd6eb838103769322f22b07ef7d693 234 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 12 233 38.712 T 29-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 SPSF3K_RS01070 c4dd6eb838103769322f22b07ef7d693 234 Gene3D G3DSA:3.20.20.70 2 234 2.8E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 417 1.2E-18 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 Gene3D G3DSA:3.30.470.20 190 324 6.6E-56 T 29-03-2018 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 SUPERFAMILY SSF52440 1 101 5.61E-30 T 29-03-2018 IPR016185 Pre-ATP-grasp domain SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 288 295 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 Gene3D G3DSA:3.30.1490.20 86 188 9.8E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 419 1.4E-146 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 Gene3D G3DSA:3.40.50.20 2 85 5.4E-31 T 29-03-2018 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 3.9E-30 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 SMART SM01209 102 294 1.7E-130 T 29-03-2018 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 419 41.706 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 Gene3D G3DSA:3.90.600.10 327 420 7.7E-21 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 SMART SM01210 327 419 2.6E-25 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 SUPERFAMILY SSF51246 326 419 5.65E-20 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 SUPERFAMILY SSF56059 103 320 2.12E-63 T 29-03-2018 SPSF3K_RS10585 a03018b219ca13fabad8fb6a87953a84 420 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 294 1.9E-80 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 Hamap MF_00050 Elongation factor Ts [tsf]. 1 341 67.139 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 Pfam PF00889 Elongation factor TS 235 323 2.1E-22 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 Pfam PF00889 Elongation factor TS 71 225 8.4E-45 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 SUPERFAMILY SSF46934 4 55 5.53E-18 T 29-03-2018 IPR009060 UBA-like GO:0005515 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 SUPERFAMILY SSF54713 56 146 1.07E-20 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 SUPERFAMILY SSF54713 235 340 5.72E-26 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 Gene3D G3DSA:3.30.479.20 159 227 4.5E-10 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 Gene3D G3DSA:3.30.479.20 231 339 1.8E-22 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 340 7.4E-95 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 Gene3D G3DSA:3.30.479.20 58 158 3.3E-20 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 SUPERFAMILY SSF54713 152 225 3.6E-15 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 SPSF3K_RS00590 9f7b01bc6dac2c0431ea09f9f2dac979 346 Gene3D G3DSA:1.10.8.10 1 56 3.0E-23 T 29-03-2018 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 PRINTS PR00063 Ribosomal protein L27 signature 65 89 7.2E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 PRINTS PR00063 Ribosomal protein L27 signature 15 39 7.2E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 PRINTS PR00063 Ribosomal protein L27 signature 40 64 7.2E-36 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 ProSitePatterns PS00831 Ribosomal protein L27 signature. 45 59 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 39 80 1.0E-17 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 12 95 26.419 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 TIGRFAM TIGR00062 L27: ribosomal protein bL27 12 92 4.9E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 Pfam PF01016 Ribosomal L27 protein 13 92 1.3E-33 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 SUPERFAMILY SSF110324 13 94 2.41E-31 T 29-03-2018 SPSF3K_RS05190 caa0968e50b0ffb1c066481db30936b2 97 Gene3D G3DSA:2.40.50.100 31 95 5.4E-27 T 29-03-2018 SPSF3K_RS07225 a3cc652e95f1b1272df80a74012a275a 110 SUPERFAMILY SSF57783 1 35 3.23E-12 T 29-03-2018 SPSF3K_RS07225 a3cc652e95f1b1272df80a74012a275a 110 SUPERFAMILY SSF82057 38 109 2.15E-27 T 29-03-2018 SPSF3K_RS07225 a3cc652e95f1b1272df80a74012a275a 110 Gene3D G3DSA:2.20.25.10 1 39 2.2E-12 T 29-03-2018 SPSF3K_RS07225 a3cc652e95f1b1272df80a74012a275a 110 Pfam PF08274 PhnA Zinc-Ribbon 2 31 1.9E-13 T 29-03-2018 IPR013987 PhnA protein, N-terminal SPSF3K_RS07225 a3cc652e95f1b1272df80a74012a275a 110 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 109 1.4E-44 T 29-03-2018 IPR004624 PhnA protein SPSF3K_RS07225 a3cc652e95f1b1272df80a74012a275a 110 Gene3D G3DSA:2.30.30.40 42 109 6.9E-35 T 29-03-2018 SPSF3K_RS07225 a3cc652e95f1b1272df80a74012a275a 110 Pfam PF03831 PhnA domain 43 109 5.4E-33 T 29-03-2018 IPR013988 PhnA protein, C-terminal SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.1E-19 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.1E-19 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.1E-19 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 5.1E-35 T 29-03-2018 IPR027486 Ribosomal protein S10 domain SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 SUPERFAMILY SSF54999 5 102 9.94E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 SMART SM01403 7 101 1.8E-55 T 29-03-2018 IPR027486 Ribosomal protein S10 domain SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 2.7E-44 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 Gene3D G3DSA:3.30.70.600 3 102 1.2E-35 T 29-03-2018 IPR027486 Ribosomal protein S10 domain SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10525 1b140eca5c1dbe2a057899ad87a6c3b7 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.562 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10145 5468c4526df8f4f33bea845b80cde9ab 194 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 55 187 6.6E-16 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPSF3K_RS10145 5468c4526df8f4f33bea845b80cde9ab 194 SMART SM00047 37 194 5.5E-11 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPSF3K_RS10145 5468c4526df8f4f33bea845b80cde9ab 194 Gene3D G3DSA:1.10.530.10 41 194 4.1E-26 T 29-03-2018 SPSF3K_RS04000 8a447559e8bea43fb9b5ea5a9187b9d8 125 SUPERFAMILY SSF54593 2 123 6.98E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS04000 8a447559e8bea43fb9b5ea5a9187b9d8 125 Gene3D G3DSA:3.10.180.10 1 125 5.3E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS04000 8a447559e8bea43fb9b5ea5a9187b9d8 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 120 4.0E-18 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPSF3K_RS08890 4c06d2188625af7130e01bbb8b090347 254 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 8.0E-15 T 29-03-2018 IPR019933 DivIVA domain SPSF3K_RS08890 4c06d2188625af7130e01bbb8b090347 254 Pfam PF05103 DivIVA protein 3 143 2.1E-42 T 29-03-2018 IPR007793 DivIVA family SPSF3K_RS08890 4c06d2188625af7130e01bbb8b090347 254 Gene3D G3DSA:1.20.5.620 37 99 0.35 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SPSF3K_RS08890 4c06d2188625af7130e01bbb8b090347 254 Gene3D G3DSA:1.20.5.620 100 154 0.015 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain SPSF3K_RS09190 cbd21886599e34cdbe4fd4efaac685ba 177 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 154 1.3E-10 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS09190 cbd21886599e34cdbe4fd4efaac685ba 177 Gene3D G3DSA:2.160.10.10 9 177 3.2E-45 T 29-03-2018 SPSF3K_RS09190 cbd21886599e34cdbe4fd4efaac685ba 177 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 128 156 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 SPSF3K_RS09190 cbd21886599e34cdbe4fd4efaac685ba 177 SUPERFAMILY SSF51161 40 176 2.36E-43 T 29-03-2018 IPR011004 Trimeric LpxA-like SPSF3K_RS10295 fdaa6e0513e66bca0ab7a183fca3f578 238 Pfam PF02378 Phosphotransferase system, EIIC 2 157 7.1E-14 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS02900 79824cdc256c8e5bad9ee922ba9a02f3 280 SUPERFAMILY SSF50182 115 172 8.17E-14 T 29-03-2018 IPR010920 LSM domain SPSF3K_RS02900 79824cdc256c8e5bad9ee922ba9a02f3 280 Gene3D G3DSA:3.30.70.100 179 278 1.1E-4 T 29-03-2018 SPSF3K_RS02900 79824cdc256c8e5bad9ee922ba9a02f3 280 SUPERFAMILY SSF82861 22 113 1.02E-15 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SPSF3K_RS02900 79824cdc256c8e5bad9ee922ba9a02f3 280 Gene3D G3DSA:2.30.30.60 130 178 5.8E-12 T 29-03-2018 SPSF3K_RS02900 79824cdc256c8e5bad9ee922ba9a02f3 280 Pfam PF00924 Mechanosensitive ion channel 72 267 1.2E-40 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SPSF3K_RS07030 477d39dbef356259f2d793dd52e98e6a 306 Gene3D G3DSA:3.40.50.300 5 306 2.4E-56 T 29-03-2018 SPSF3K_RS07030 477d39dbef356259f2d793dd52e98e6a 306 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 7 306 7.2E-98 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SPSF3K_RS07030 477d39dbef356259f2d793dd52e98e6a 306 SUPERFAMILY SSF52540 4 305 3.67E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07030 477d39dbef356259f2d793dd52e98e6a 306 Hamap MF_00215 Pantothenate kinase [coaA]. 1 306 140.715 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SPSF3K_RS07030 477d39dbef356259f2d793dd52e98e6a 306 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 86 226 3.0E-15 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 SPSF3K_RS07030 477d39dbef356259f2d793dd52e98e6a 306 PIRSF PIRSF000545 1 306 6.9E-132 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 SPSF3K_RS07455 382304bc7df5920a04cd861fcb7b4029 441 Gene3D G3DSA:3.40.50.300 285 434 3.1E-20 T 29-03-2018 SPSF3K_RS07455 382304bc7df5920a04cd861fcb7b4029 441 SUPERFAMILY SSF52540 117 173 1.15E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07455 382304bc7df5920a04cd861fcb7b4029 441 SUPERFAMILY SSF52540 290 436 1.15E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07455 382304bc7df5920a04cd861fcb7b4029 441 Pfam PF00271 Helicase conserved C-terminal domain 300 395 1.0E-4 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS07455 382304bc7df5920a04cd861fcb7b4029 441 Pfam PF00176 SNF2 family N-terminal domain 17 258 1.5E-20 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 SPSF3K_RS07455 382304bc7df5920a04cd861fcb7b4029 441 SUPERFAMILY SSF52540 2 204 1.16E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07455 382304bc7df5920a04cd861fcb7b4029 441 Gene3D G3DSA:3.40.50.10810 1 224 6.6E-30 T 29-03-2018 SPSF3K_RS07455 382304bc7df5920a04cd861fcb7b4029 441 SMART SM00487 2 188 3.8E-12 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS02710 81162393399c35c63b47e17f5ab0f697 108 Gene3D G3DSA:1.10.10.10 9 94 5.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02710 81162393399c35c63b47e17f5ab0f697 108 Pfam PF06970 Replication initiator protein A (RepA) N-terminus 6 80 2.8E-23 T 29-03-2018 IPR010724 Replication initiator A, N-terminal SPSF3K_RS04325 04e3e90e4bea66c043b4b16ec258bab9 422 SUPERFAMILY SSF51556 75 375 5.28E-81 T 29-03-2018 IPR032466 Metal-dependent hydrolase SPSF3K_RS04325 04e3e90e4bea66c043b4b16ec258bab9 422 Gene3D G3DSA:3.20.20.140 89 374 7.0E-53 T 29-03-2018 SPSF3K_RS04325 04e3e90e4bea66c043b4b16ec258bab9 422 Gene3D G3DSA:2.30.40.10 21 88 1.3E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPSF3K_RS04325 04e3e90e4bea66c043b4b16ec258bab9 422 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 414 41.773 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04325 04e3e90e4bea66c043b4b16ec258bab9 422 Pfam PF01979 Amidohydrolase family 72 414 4.0E-21 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 SPSF3K_RS04325 04e3e90e4bea66c043b4b16ec258bab9 422 TIGRFAM TIGR01224 hutI: imidazolonepropionase 36 412 2.6E-139 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 SPSF3K_RS04325 04e3e90e4bea66c043b4b16ec258bab9 422 SUPERFAMILY SSF51338 4 76 9.1E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPSF3K_RS04325 04e3e90e4bea66c043b4b16ec258bab9 422 SUPERFAMILY SSF51338 374 416 9.1E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPSF3K_RS10535 65ce0a91e016da5ccbf0de35d7eaf533 494 Gene3D G3DSA:3.90.1380.10 3 89 1.7E-24 T 29-03-2018 IPR029144 Threonine synthase, N-terminal SPSF3K_RS10535 65ce0a91e016da5ccbf0de35d7eaf533 494 Pfam PF14821 Threonine synthase N terminus 5 80 2.9E-21 T 29-03-2018 IPR029144 Threonine synthase, N-terminal SPSF3K_RS10535 65ce0a91e016da5ccbf0de35d7eaf533 494 Gene3D G3DSA:3.40.50.1100 208 444 5.0E-78 T 29-03-2018 SPSF3K_RS10535 65ce0a91e016da5ccbf0de35d7eaf533 494 TIGRFAM TIGR00260 thrC: threonine synthase 82 445 9.0E-71 T 29-03-2018 IPR004450 Threonine synthase-like SPSF3K_RS10535 65ce0a91e016da5ccbf0de35d7eaf533 494 SUPERFAMILY SSF53686 3 480 3.98E-144 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SPSF3K_RS10535 65ce0a91e016da5ccbf0de35d7eaf533 494 Gene3D G3DSA:3.40.50.1100 107 207 4.3E-18 T 29-03-2018 SPSF3K_RS10535 65ce0a91e016da5ccbf0de35d7eaf533 494 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 102 416 5.4E-14 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SPSF3K_RS05545 b36a3383a399acf6a91ef519a8376e00 229 PRINTS PR01217 Proline rich extensin signature 33 49 2.6E-11 T 29-03-2018 SPSF3K_RS05545 b36a3383a399acf6a91ef519a8376e00 229 PRINTS PR01217 Proline rich extensin signature 56 68 2.6E-11 T 29-03-2018 SPSF3K_RS05545 b36a3383a399acf6a91ef519a8376e00 229 PRINTS PR01217 Proline rich extensin signature 105 121 2.6E-11 T 29-03-2018 SPSF3K_RS05545 b36a3383a399acf6a91ef519a8376e00 229 PRINTS PR01217 Proline rich extensin signature 74 95 2.6E-11 T 29-03-2018 SPSF3K_RS05545 b36a3383a399acf6a91ef519a8376e00 229 Pfam PF00746 LPXTG cell wall anchor motif 188 227 1.9E-9 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor SPSF3K_RS05545 b36a3383a399acf6a91ef519a8376e00 229 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 194 226 6.7E-6 T 29-03-2018 SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 Gene3D G3DSA:3.30.565.10 361 579 3.8E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 579 5.8E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 SMART SM00387 471 580 6.6E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 Pfam PF07694 5TMR of 5TMR-LYT 26 205 4.3E-44 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 Gene3D G3DSA:3.30.450.40 155 360 1.6E-4 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 SMART SM00065 238 373 0.0065 T 29-03-2018 IPR003018 GAF domain GO:0005515 SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 Pfam PF13492 GAF domain 243 364 2.2E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 SUPERFAMILY SSF55874 434 578 1.31E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 SUPERFAMILY SSF55781 244 364 1.12E-7 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS02925 855ccd517130bc0d88aa234d24266638 585 Pfam PF06580 Histidine kinase 378 456 8.9E-24 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 SPSF3K_RS07615 d43856b80353847dd45e106fe2317340 217 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 55 64 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS07615 d43856b80353847dd45e106fe2317340 217 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 4 209 4.9E-74 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS07615 d43856b80353847dd45e106fe2317340 217 Gene3D G3DSA:3.40.470.10 2 217 8.5E-92 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS07615 d43856b80353847dd45e106fe2317340 217 SMART SM00986 47 205 9.2E-34 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS07615 d43856b80353847dd45e106fe2317340 217 SMART SM00987 47 205 9.2E-34 T 29-03-2018 SPSF3K_RS07615 d43856b80353847dd45e106fe2317340 217 Pfam PF03167 Uracil DNA glycosylase superfamily 52 204 5.8E-21 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS07615 d43856b80353847dd45e106fe2317340 217 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 3 216 38.585 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS07615 d43856b80353847dd45e106fe2317340 217 SUPERFAMILY SSF52141 3 215 1.81E-84 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 SPSF3K_RS03910 5d0d37fd34034de4fadcb006b6fa4f02 158 SUPERFAMILY SSF55811 17 135 1.26E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPSF3K_RS03910 5d0d37fd34034de4fadcb006b6fa4f02 158 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPSF3K_RS03910 5d0d37fd34034de4fadcb006b6fa4f02 158 Pfam PF00293 NUDIX domain 23 134 3.0E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SPSF3K_RS03910 5d0d37fd34034de4fadcb006b6fa4f02 158 Gene3D G3DSA:3.90.79.10 1 146 2.4E-22 T 29-03-2018 SPSF3K_RS03910 5d0d37fd34034de4fadcb006b6fa4f02 158 PRINTS PR00502 NUDIX hydrolase family signature 45 59 7.4E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SPSF3K_RS03910 5d0d37fd34034de4fadcb006b6fa4f02 158 PRINTS PR00502 NUDIX hydrolase family signature 59 74 7.4E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 202 446 1.4E-87 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 122 135 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 Gene3D G3DSA:3.40.50.10860 63 201 3.4E-56 T 29-03-2018 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 185 6.2E-53 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 PIRSF PIRSF000185 20 448 2.4E-122 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 3.1E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 193 215 3.1E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 3.1E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 235 255 3.1E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 Gene3D G3DSA:3.40.50.720 209 373 3.8E-45 T 29-03-2018 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 Gene3D G3DSA:1.10.285.10 374 448 4.6E-28 T 29-03-2018 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 Gene3D G3DSA:1.10.285.10 6 62 4.6E-8 T 29-03-2018 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 SUPERFAMILY SSF51735 202 447 1.69E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 SMART SM00839 204 446 4.2E-92 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 SPSF3K_RS05385 ff1cfcf78c93f435405de54a7a1703fe 448 SUPERFAMILY SSF53223 6 196 2.78E-74 T 29-03-2018 SPSF3K_RS08855 a3668db4cd4b6ad4b6ee1143c4777df8 244 PIRSF PIRSF039085 2 244 4.4E-114 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SPSF3K_RS08855 a3668db4cd4b6ad4b6ee1143c4777df8 244 SUPERFAMILY SSF52540 5 238 1.1E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08855 a3668db4cd4b6ad4b6ee1143c4777df8 244 SMART SM00382 30 225 5.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08855 a3668db4cd4b6ad4b6ee1143c4777df8 244 Pfam PF00005 ABC transporter 21 169 2.2E-38 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08855 a3668db4cd4b6ad4b6ee1143c4777df8 244 Gene3D G3DSA:3.40.50.300 2 243 4.2E-78 T 29-03-2018 SPSF3K_RS08855 a3668db4cd4b6ad4b6ee1143c4777df8 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS01125 550adf26b31f82eb4e5b9e26cf2a5350 194 SUPERFAMILY SSF110455 12 130 1.57E-34 T 29-03-2018 SPSF3K_RS01125 550adf26b31f82eb4e5b9e26cf2a5350 194 SMART SM00493 15 88 0.0053 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS01125 550adf26b31f82eb4e5b9e26cf2a5350 194 Pfam PF13331 Domain of unknown function (DUF4093) 106 191 7.8E-29 T 29-03-2018 IPR025156 Ribonuclease M5, C-terminal domain SPSF3K_RS01125 550adf26b31f82eb4e5b9e26cf2a5350 194 Hamap MF_01469 Ribonuclease M5 [rnmV]. 13 193 29.952 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 SPSF3K_RS01125 550adf26b31f82eb4e5b9e26cf2a5350 194 Pfam PF13662 Toprim domain 16 81 1.0E-5 T 29-03-2018 IPR006171 TOPRIM domain SPSF3K_RS01125 550adf26b31f82eb4e5b9e26cf2a5350 194 Gene3D G3DSA:3.40.1360.20 11 139 1.9E-17 T 29-03-2018 SPSF3K_RS01125 550adf26b31f82eb4e5b9e26cf2a5350 194 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 13 190 2.0E-44 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4 120 9.2E-39 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 279 6.0E-70 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 SUPERFAMILY SSF51735 122 280 4.38E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 SUPERFAMILY SSF53223 1 121 2.11E-39 T 29-03-2018 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 282 38.123 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 2.4E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 2.4E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 2.4E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 2.4E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 2.4E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 2.4E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 2.4E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 Gene3D G3DSA:3.40.50.720 140 263 2.1E-41 T 29-03-2018 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 SPSF3K_RS08835 3f14df3ae9cf7c2bcdb605cd5ec8f9b7 284 Gene3D G3DSA:3.40.50.10860 10 139 3.5E-46 T 29-03-2018 SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 SUPERFAMILY SSF46785 88 133 6.35E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 Gene3D G3DSA:1.10.1790.10 196 299 3.9E-6 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 Gene3D G3DSA:1.10.10.10 1 69 0.013 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 Gene3D G3DSA:1.10.1790.10 300 412 9.7E-20 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 SUPERFAMILY SSF63520 310 408 8.37E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 Pfam PF00874 PRD domain 213 297 4.7E-6 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 Pfam PF00874 PRD domain 321 408 2.5E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 Gene3D G3DSA:1.10.10.10 87 157 1.7E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 Pfam PF08279 HTH domain 102 151 4.2E-6 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 SPSF3K_RS00775 a77e06627881b43effd7dcde048c81e3 557 Gene3D G3DSA:3.40.50.2300 419 507 5.0E-8 T 29-03-2018 SPSF3K_RS02955 1b78463a7aa94642a6fcdfca5f1211a9 293 Gene3D G3DSA:3.20.20.70 1 293 4.1E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS02955 1b78463a7aa94642a6fcdfca5f1211a9 293 PIRSF PIRSF001359 1 293 8.9E-115 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPSF3K_RS02955 1b78463a7aa94642a6fcdfca5f1211a9 293 SUPERFAMILY SSF51569 1 293 1.83E-96 T 29-03-2018 SPSF3K_RS02955 1b78463a7aa94642a6fcdfca5f1211a9 293 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 133 144 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPSF3K_RS02955 1b78463a7aa94642a6fcdfca5f1211a9 293 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 293 2.7E-92 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPSF3K_RS02955 1b78463a7aa94642a6fcdfca5f1211a9 293 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPSF3K_RS02955 1b78463a7aa94642a6fcdfca5f1211a9 293 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 292 4.8E-96 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPSF3K_RS02955 1b78463a7aa94642a6fcdfca5f1211a9 293 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 293 1.4E-120 T 29-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 SPSF3K_RS00440 8e049e7ea8e884a950830ebb58e23d41 68 Gene3D G3DSA:1.10.260.40 3 68 9.6E-8 T 29-03-2018 SPSF3K_RS00440 8e049e7ea8e884a950830ebb58e23d41 68 SUPERFAMILY SSF47413 4 48 2.56E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS07725 d354c6d2fe66841f6e7b710a6afe07b9 600 Pfam PF13727 CoA-binding domain 77 237 3.7E-14 T 29-03-2018 SPSF3K_RS07725 d354c6d2fe66841f6e7b710a6afe07b9 600 Gene3D G3DSA:3.40.50.720 137 263 1.6E-28 T 29-03-2018 SPSF3K_RS07725 d354c6d2fe66841f6e7b710a6afe07b9 600 SUPERFAMILY SSF51735 279 543 1.11E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS07725 d354c6d2fe66841f6e7b710a6afe07b9 600 Pfam PF02719 Polysaccharide biosynthesis protein 282 563 7.8E-123 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain SPSF3K_RS07725 d354c6d2fe66841f6e7b710a6afe07b9 600 SUPERFAMILY SSF51735 139 269 9.45E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS07725 d354c6d2fe66841f6e7b710a6afe07b9 600 Gene3D G3DSA:3.40.50.720 275 600 5.5E-66 T 29-03-2018 SPSF3K_RS08760 ec7ed1fca05ab6416d6e6a08a97e87de 230 Gene3D G3DSA:3.40.50.1240 1 230 4.4E-58 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS08760 ec7ed1fca05ab6416d6e6a08a97e87de 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 123 5.6E-28 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS08760 ec7ed1fca05ab6416d6e6a08a97e87de 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 129 213 1.2E-4 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS08760 ec7ed1fca05ab6416d6e6a08a97e87de 230 PIRSF PIRSF000709 172 218 22.0 T 29-03-2018 SPSF3K_RS08760 ec7ed1fca05ab6416d6e6a08a97e87de 230 PIRSF PIRSF000709 3 110 1.8E-6 T 29-03-2018 SPSF3K_RS08760 ec7ed1fca05ab6416d6e6a08a97e87de 230 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 42.415 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SPSF3K_RS08760 ec7ed1fca05ab6416d6e6a08a97e87de 230 SUPERFAMILY SSF53254 1 221 4.57E-71 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS08760 ec7ed1fca05ab6416d6e6a08a97e87de 230 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 229 4.6E-103 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 SPSF3K_RS08760 ec7ed1fca05ab6416d6e6a08a97e87de 230 SMART SM00855 3 189 1.0E-22 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 Pfam PF00005 ABC transporter 18 168 1.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 Pfam PF00005 ABC transporter 267 420 3.1E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 Gene3D G3DSA:3.40.50.300 238 488 1.1E-40 T 29-03-2018 SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 SMART SM00382 275 469 3.9E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 SMART SM00382 27 223 8.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 Gene3D G3DSA:3.40.50.300 1 237 3.6E-56 T 29-03-2018 SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 ProSitePatterns PS00211 ABC transporters family signature. 393 407 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 SUPERFAMILY SSF52540 3 229 1.89E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09015 daf67c55d5d689fe4def2b8551bdbea0 492 SUPERFAMILY SSF52540 264 479 1.63E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03630 88cd0bccf4ee813d1d3bfe7b9e1c3433 220 SUPERFAMILY SSF54631 1 131 4.13E-35 T 29-03-2018 SPSF3K_RS03630 88cd0bccf4ee813d1d3bfe7b9e1c3433 220 SUPERFAMILY SSF55021 137 197 1.11E-6 T 29-03-2018 SPSF3K_RS03630 88cd0bccf4ee813d1d3bfe7b9e1c3433 220 Pfam PF00571 CBS domain 77 131 1.0E-13 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS03630 88cd0bccf4ee813d1d3bfe7b9e1c3433 220 Pfam PF00571 CBS domain 3 52 1.0E-13 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS03630 88cd0bccf4ee813d1d3bfe7b9e1c3433 220 Gene3D G3DSA:3.30.70.260 138 220 2.1E-6 T 29-03-2018 SPSF3K_RS03630 88cd0bccf4ee813d1d3bfe7b9e1c3433 220 Gene3D G3DSA:3.10.580.10 1 137 1.7E-32 T 29-03-2018 SPSF3K_RS03630 88cd0bccf4ee813d1d3bfe7b9e1c3433 220 SMART SM00116 10 57 1.8E-11 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS03630 88cd0bccf4ee813d1d3bfe7b9e1c3433 220 SMART SM00116 84 131 1.0E-12 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS06700 b744e4961e184cea69a711e16b53189a 406 Gene3D G3DSA:3.40.630.10 2 292 7.9E-57 T 29-03-2018 SPSF3K_RS06700 b744e4961e184cea69a711e16b53189a 406 PIRSF PIRSF005962 1 406 2.1E-104 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 SPSF3K_RS06700 b744e4961e184cea69a711e16b53189a 406 SUPERFAMILY SSF53187 4 208 1.45E-71 T 29-03-2018 SPSF3K_RS06700 b744e4961e184cea69a711e16b53189a 406 SUPERFAMILY SSF53187 311 404 1.45E-71 T 29-03-2018 SPSF3K_RS06700 b744e4961e184cea69a711e16b53189a 406 Pfam PF01546 Peptidase family M20/M25/M40 72 388 5.5E-22 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SPSF3K_RS06700 b744e4961e184cea69a711e16b53189a 406 Pfam PF07687 Peptidase dimerisation domain 194 292 1.1E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SPSF3K_RS06700 b744e4961e184cea69a711e16b53189a 406 SUPERFAMILY SSF55031 196 299 3.4E-28 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SPSF3K_RS06700 b744e4961e184cea69a711e16b53189a 406 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 382 4.5E-81 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 SPSF3K_RS10120 fb2909d96b37e4f79188c85d4c5a958a 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 262 3.4E-42 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SPSF3K_RS10120 fb2909d96b37e4f79188c85d4c5a958a 263 SUPERFAMILY SSF52096 1 261 4.77E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SPSF3K_RS10120 fb2909d96b37e4f79188c85d4c5a958a 263 Gene3D G3DSA:3.90.226.10 1 263 9.5E-61 T 29-03-2018 SPSF3K_RS10645 1144f85f92fbbb8f7541ac3760da633c 257 SUPERFAMILY SSF50249 3 77 1.06E-11 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS10645 1144f85f92fbbb8f7541ac3760da633c 257 SUPERFAMILY SSF57863 81 232 1.02E-36 T 29-03-2018 SPSF3K_RS10645 1144f85f92fbbb8f7541ac3760da633c 257 Pfam PF02565 Recombination protein O C terminal 83 237 7.0E-36 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SPSF3K_RS10645 1144f85f92fbbb8f7541ac3760da633c 257 TIGRFAM TIGR00613 reco: DNA repair protein RecO 6 243 1.0E-74 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SPSF3K_RS10645 1144f85f92fbbb8f7541ac3760da633c 257 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 24.437 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SPSF3K_RS10645 1144f85f92fbbb8f7541ac3760da633c 257 Pfam PF11967 Recombination protein O N terminal 1 77 7.8E-17 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal SPSF3K_RS10645 1144f85f92fbbb8f7541ac3760da633c 257 Gene3D G3DSA:2.40.50.140 1 81 2.1E-14 T 29-03-2018 SPSF3K_RS07715 7d13f19eca12158d69e7752a49a846da 282 Gene3D G3DSA:3.40.50.720 1 30 0.053 T 29-03-2018 SPSF3K_RS07715 7d13f19eca12158d69e7752a49a846da 282 Gene3D G3DSA:3.40.50.720 31 281 1.1E-21 T 29-03-2018 SPSF3K_RS07715 7d13f19eca12158d69e7752a49a846da 282 SUPERFAMILY SSF51735 1 277 5.29E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS07715 7d13f19eca12158d69e7752a49a846da 282 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 161 5.8E-18 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SPSF3K_RS01795 3590f92c335eb3753c2f9d88ce777fd6 99 Pfam PF00581 Rhodanese-like domain 9 95 8.5E-16 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01795 3590f92c335eb3753c2f9d88ce777fd6 99 SMART SM00450 5 99 8.0E-15 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01795 3590f92c335eb3753c2f9d88ce777fd6 99 Gene3D G3DSA:3.40.250.10 1 98 9.2E-25 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS01795 3590f92c335eb3753c2f9d88ce777fd6 99 SUPERFAMILY SSF52821 6 95 1.96E-28 T 29-03-2018 IPR001763 Rhodanese-like domain SPSF3K_RS03325 19e73a2cff425a464b747ec68661bfa5 80 Pfam PF03672 Uncharacterised protein family (UPF0154) 10 67 2.2E-21 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 SPSF3K_RS03325 19e73a2cff425a464b747ec68661bfa5 80 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 26 62 7.0E-14 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 SPSF3K_RS03325 19e73a2cff425a464b747ec68661bfa5 80 Hamap MF_00363 UPF0154 protein . 2 72 19.958 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 SPSF3K_RS10610 df3306021fe512323a7ddd41605ceae6 184 Pfam PF00551 Formyl transferase 3 176 3.0E-45 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPSF3K_RS10610 df3306021fe512323a7ddd41605ceae6 184 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 179 2.9E-58 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 SPSF3K_RS10610 df3306021fe512323a7ddd41605ceae6 184 SUPERFAMILY SSF53328 3 178 1.7E-51 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPSF3K_RS10610 df3306021fe512323a7ddd41605ceae6 184 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 4 182 28.543 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 SPSF3K_RS10610 df3306021fe512323a7ddd41605ceae6 184 Gene3D G3DSA:3.40.50.170 1 183 6.6E-55 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPSF3K_RS10195 38fc22a0821051f7c88a387794ea8596 479 Gene3D G3DSA:1.10.10.410 414 475 2.9E-13 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal SPSF3K_RS10195 38fc22a0821051f7c88a387794ea8596 479 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 475 36.505 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SPSF3K_RS10195 38fc22a0821051f7c88a387794ea8596 479 Pfam PF02934 GatB/GatE catalytic domain 6 288 5.5E-109 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 SPSF3K_RS10195 38fc22a0821051f7c88a387794ea8596 479 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 474 1.6E-162 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SPSF3K_RS10195 38fc22a0821051f7c88a387794ea8596 479 Pfam PF02637 GatB domain 327 474 2.4E-46 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 SPSF3K_RS10195 38fc22a0821051f7c88a387794ea8596 479 SUPERFAMILY SSF55931 4 295 2.49E-117 T 29-03-2018 SPSF3K_RS10195 38fc22a0821051f7c88a387794ea8596 479 SUPERFAMILY SSF89095 297 401 8.63E-32 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 SPSF3K_RS10195 38fc22a0821051f7c88a387794ea8596 479 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 143 157 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 SPSF3K_RS10195 38fc22a0821051f7c88a387794ea8596 479 SMART SM00845 327 474 1.8E-61 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 SPSF3K_RS03640 0e01b3ab20344f1f5f328d0169709052 291 Pfam PF13177 DNA polymerase III, delta subunit 8 162 1.1E-53 T 29-03-2018 SPSF3K_RS03640 0e01b3ab20344f1f5f328d0169709052 291 Gene3D G3DSA:3.30.450.20 169 279 0.0047 T 29-03-2018 SPSF3K_RS03640 0e01b3ab20344f1f5f328d0169709052 291 SUPERFAMILY SSF52540 8 162 2.04E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03640 0e01b3ab20344f1f5f328d0169709052 291 Gene3D G3DSA:3.40.50.300 8 161 3.2E-24 T 29-03-2018 SPSF3K_RS03010 d69782642afcd4bf6b6d53d8ef2c4832 251 PIRSF PIRSF029008 1 250 1.0E-69 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA SPSF3K_RS03010 d69782642afcd4bf6b6d53d8ef2c4832 251 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 245 2.7E-41 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA SPSF3K_RS03010 d69782642afcd4bf6b6d53d8ef2c4832 251 Hamap MF_01124 Adapter protein MecA [mecA]. 1 249 25.47 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA SPSF3K_RS09415 068303658d4b896c8f6dde6a8b1af6fe 255 SUPERFAMILY SSF51197 154 254 1.51E-20 T 29-03-2018 SPSF3K_RS09415 068303658d4b896c8f6dde6a8b1af6fe 255 Pfam PF07972 NrdI Flavodoxin like 6 143 2.3E-37 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI SPSF3K_RS09415 068303658d4b896c8f6dde6a8b1af6fe 255 Gene3D G3DSA:3.40.50.360 4 151 3.2E-14 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS09415 068303658d4b896c8f6dde6a8b1af6fe 255 SUPERFAMILY SSF52218 3 148 1.63E-14 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS09415 068303658d4b896c8f6dde6a8b1af6fe 255 Pfam PF09313 Domain of unknown function (DUF1971) 164 243 9.2E-15 T 29-03-2018 IPR015392 Domain of unknown function DUF1971 SPSF3K_RS09415 068303658d4b896c8f6dde6a8b1af6fe 255 Gene3D G3DSA:2.60.120.10 156 255 2.1E-23 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 SUPERFAMILY SSF52540 60 393 6.54E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 SMART SM00994 10 49 2.2E-21 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 SMART SM00382 110 260 2.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 Gene3D G3DSA:3.40.50.300 54 310 1.4E-69 T 29-03-2018 SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 7 406 1.7E-193 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 Pfam PF07724 AAA domain (Cdc48 subfamily) 110 305 3.2E-49 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 390 3.4E-18 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 Gene3D G3DSA:1.10.8.60 312 403 6.5E-34 T 29-03-2018 SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 Pfam PF06689 ClpX C4-type zinc finger 12 48 2.0E-17 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 409 50.949 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 SMART SM01086 312 406 1.1E-34 T 29-03-2018 IPR019489 Clp ATPase, C-terminal SPSF3K_RS05450 bd3fca553498a95fd0745a1fb3075d9b 409 SUPERFAMILY SSF57716 11 46 3.56E-11 T 29-03-2018 SPSF3K_RS00285 62e599734574296ef361c763e1d21e54 249 SUPERFAMILY SSF47413 1 66 2.68E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS00285 62e599734574296ef361c763e1d21e54 249 Pfam PF01381 Helix-turn-helix 7 61 3.6E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS00285 62e599734574296ef361c763e1d21e54 249 Gene3D G3DSA:1.10.3100.10 1 91 7.6E-23 T 29-03-2018 IPR027910 YdiL-like domain SPSF3K_RS00285 62e599734574296ef361c763e1d21e54 249 SMART SM00530 6 61 7.4E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS06780 6db3ab0a8344a025b1df188cccf3b963 356 Pfam PF00589 Phage integrase family 176 344 2.8E-24 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS06780 6db3ab0a8344a025b1df188cccf3b963 356 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 33 122 3.4E-7 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPSF3K_RS06780 6db3ab0a8344a025b1df188cccf3b963 356 SUPERFAMILY SSF56349 20 354 1.44E-33 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPSF3K_RS06780 6db3ab0a8344a025b1df188cccf3b963 356 Gene3D G3DSA:1.10.443.10 156 356 1.6E-31 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS06780 6db3ab0a8344a025b1df188cccf3b963 356 Hamap MF_01816 Tyrosine recombinase XerS [xerS]. 1 356 62.702 T 29-03-2018 IPR023670 Tyrosine recombinase XerS GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 SPSF3K_RS06780 6db3ab0a8344a025b1df188cccf3b963 356 Gene3D G3DSA:1.10.150.130 9 130 1.1E-15 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SPSF3K_RS09795 89ea4ac883b29872e2427be43a07e70a 316 SUPERFAMILY SSF81799 118 219 4.97E-35 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS09795 89ea4ac883b29872e2427be43a07e70a 316 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 313 2.7E-118 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS09795 89ea4ac883b29872e2427be43a07e70a 316 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 37.512 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS09795 89ea4ac883b29872e2427be43a07e70a 316 Gene3D G3DSA:1.10.150.170 119 221 2.5E-39 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS09795 89ea4ac883b29872e2427be43a07e70a 316 Gene3D G3DSA:3.40.50.150 1 118 2.7E-8 T 29-03-2018 SPSF3K_RS09795 89ea4ac883b29872e2427be43a07e70a 316 SUPERFAMILY SSF53335 6 117 1.37E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS09795 89ea4ac883b29872e2427be43a07e70a 316 SUPERFAMILY SSF53335 219 314 1.37E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS09795 89ea4ac883b29872e2427be43a07e70a 316 Pfam PF01795 MraW methylase family 4 314 2.4E-132 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS09795 89ea4ac883b29872e2427be43a07e70a 316 PIRSF PIRSF004486 1 315 3.2E-107 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS02150 43601a1be78086e92dada14cac59fb59 497 SUPERFAMILY SSF89550 153 378 2.55E-27 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SPSF3K_RS02150 43601a1be78086e92dada14cac59fb59 497 Gene3D G3DSA:3.20.20.140 151 341 2.7E-14 T 29-03-2018 SPSF3K_RS03855 97a31d8f6efaaa946d0dfeacdbbc793e 284 Pfam PF13509 S1 domain 9 62 2.2E-8 T 29-03-2018 SPSF3K_RS03855 97a31d8f6efaaa946d0dfeacdbbc793e 284 Gene3D G3DSA:2.40.50.140 53 131 0.0086 T 29-03-2018 SPSF3K_RS03855 97a31d8f6efaaa946d0dfeacdbbc793e 284 PIRSF PIRSF012524 1 284 6.0E-106 T 29-03-2018 IPR014464 Conserved virulence factor B SPSF3K_RS03855 97a31d8f6efaaa946d0dfeacdbbc793e 284 Gene3D G3DSA:2.40.50.140 152 221 3.6E-6 T 29-03-2018 SPSF3K_RS03855 97a31d8f6efaaa946d0dfeacdbbc793e 284 Gene3D G3DSA:1.10.10.10 224 283 3.3E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04125 e9058daf3ac6fd011ebc8f583af257f9 215 Gene3D G3DSA:1.10.3720.10 2 215 6.7E-40 T 29-03-2018 SPSF3K_RS04125 e9058daf3ac6fd011ebc8f583af257f9 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 211 6.3E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04125 e9058daf3ac6fd011ebc8f583af257f9 215 SUPERFAMILY SSF161098 13 193 6.8E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04125 e9058daf3ac6fd011ebc8f583af257f9 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 102 3.1E-19 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPSF3K_RS02175 ac889c7ca6f952fb214b74ee67ac885c 374 Gene3D G3DSA:3.40.1710.10 44 194 2.9E-6 T 29-03-2018 SPSF3K_RS02175 ac889c7ca6f952fb214b74ee67ac885c 374 Pfam PF12698 ABC-2 family transporter protein 17 365 5.0E-45 T 29-03-2018 SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 Gene3D G3DSA:3.40.50.300 18 181 4.1E-26 T 29-03-2018 SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 253 326 1.2E-31 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 SMART SM00382 51 184 6.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 4 235 3.8E-114 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 332 167.707 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 326 3.6E-141 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 SUPERFAMILY SSF46785 257 328 9.98E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 Gene3D G3DSA:1.10.8.60 184 254 4.8E-31 T 29-03-2018 SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 SUPERFAMILY SSF52540 20 251 3.41E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 250 332 1.0E-37 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SPSF3K_RS10560 7e84a66200f0492c895162b5dca14d27 332 Gene3D G3DSA:1.10.10.10 257 327 1.8E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00765 509caf142242b10b991be8c8f1225138 287 Pfam PF01261 Xylose isomerase-like TIM barrel 22 233 4.1E-40 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SPSF3K_RS00765 509caf142242b10b991be8c8f1225138 287 Gene3D G3DSA:3.20.20.150 2 287 8.4E-54 T 29-03-2018 SPSF3K_RS00765 509caf142242b10b991be8c8f1225138 287 SUPERFAMILY SSF51658 11 283 1.7E-53 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SPSF3K_RS00765 509caf142242b10b991be8c8f1225138 287 TIGRFAM TIGR00542 hxl6Piso_put: putative hexulose-6-phosphate isomerase 4 284 1.6E-112 T 29-03-2018 IPR004560 L-ribulose-5-phosphate 3-epimerase GO:0005975|GO:0016861 KEGG: 00053+5.1.3.22|MetaCyc: PWY-6961 SPSF3K_RS00185 990e8b4ee75fbf7a47cf7d60115bd9ac 178 Gene3D G3DSA:1.10.10.60 46 161 3.7E-5 T 29-03-2018 SPSF3K_RS00185 990e8b4ee75fbf7a47cf7d60115bd9ac 178 SUPERFAMILY SSF46689 4 64 7.09E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS00185 990e8b4ee75fbf7a47cf7d60115bd9ac 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS00185 990e8b4ee75fbf7a47cf7d60115bd9ac 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS00185 990e8b4ee75fbf7a47cf7d60115bd9ac 178 Gene3D G3DSA:1.10.10.60 2 45 1.6E-14 T 29-03-2018 SPSF3K_RS00185 990e8b4ee75fbf7a47cf7d60115bd9ac 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 6.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS02885 992708965b89e20372ac61fb0c59b669 250 Pfam PF08543 Phosphomethylpyrimidine kinase 13 246 1.0E-57 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 SPSF3K_RS02885 992708965b89e20372ac61fb0c59b669 250 Gene3D G3DSA:3.40.1190.20 1 247 1.0E-43 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS02885 992708965b89e20372ac61fb0c59b669 250 SUPERFAMILY SSF53613 4 246 2.34E-55 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS05185 321e1a9133c44fd57d87b0ac62872c3d 107 SUPERFAMILY SSF118010 1 105 4.84E-30 T 29-03-2018 IPR007422 Cysteine protease Prp SPSF3K_RS05185 321e1a9133c44fd57d87b0ac62872c3d 107 Pfam PF04327 Cysteine protease Prp 1 102 2.6E-24 T 29-03-2018 IPR007422 Cysteine protease Prp SPSF3K_RS05185 321e1a9133c44fd57d87b0ac62872c3d 107 Gene3D G3DSA:3.30.70.1490 2 107 1.3E-29 T 29-03-2018 IPR007422 Cysteine protease Prp SPSF3K_RS06755 bc1d74285b7a8f20bdc6686a081d991c 120 Pfam PF02493 MORN repeat 40 62 1.9E-4 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS06755 bc1d74285b7a8f20bdc6686a081d991c 120 Pfam PF02493 MORN repeat 63 80 8.1E-5 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS06755 bc1d74285b7a8f20bdc6686a081d991c 120 Pfam PF02493 MORN repeat 86 102 7.6E-5 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS06755 bc1d74285b7a8f20bdc6686a081d991c 120 Gene3D G3DSA:2.20.110.10 41 120 5.6E-18 T 29-03-2018 SPSF3K_RS06755 bc1d74285b7a8f20bdc6686a081d991c 120 SMART SM00698 84 105 0.32 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS06755 bc1d74285b7a8f20bdc6686a081d991c 120 SMART SM00698 38 59 0.32 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS06755 bc1d74285b7a8f20bdc6686a081d991c 120 SMART SM00698 61 82 0.0026 T 29-03-2018 IPR003409 MORN motif SPSF3K_RS06755 bc1d74285b7a8f20bdc6686a081d991c 120 SUPERFAMILY SSF82185 35 117 1.57E-19 T 29-03-2018 SPSF3K_RS01505 3c161a56aa9ac769e0c9e6b19d748004 464 SUPERFAMILY SSF49899 356 451 4.83E-8 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SPSF3K_RS01505 3c161a56aa9ac769e0c9e6b19d748004 464 Gene3D G3DSA:2.115.10.20 35 358 8.8E-93 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SPSF3K_RS01505 3c161a56aa9ac769e0c9e6b19d748004 464 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 379 447 2.5E-6 T 29-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal SPSF3K_RS01505 3c161a56aa9ac769e0c9e6b19d748004 464 SMART SM00640 30 436 4.9E-107 T 29-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 SPSF3K_RS01505 3c161a56aa9ac769e0c9e6b19d748004 464 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 30 326 1.8E-98 T 29-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal SPSF3K_RS01505 3c161a56aa9ac769e0c9e6b19d748004 464 SUPERFAMILY SSF75005 20 331 2.36E-107 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SPSF3K_RS01505 3c161a56aa9ac769e0c9e6b19d748004 464 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 15 446 9.4E-113 T 29-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 SPSF3K_RS01505 3c161a56aa9ac769e0c9e6b19d748004 464 Gene3D G3DSA:2.60.120.560 359 462 3.5E-7 T 29-03-2018 SPSF3K_RS00745 c778ea5f87b87739046f5bce74a2238f 477 Pfam PF03611 PTS system sugar-specific permease component 14 421 2.3E-112 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 Gene3D G3DSA:3.90.79.10 2 160 1.7E-31 T 29-03-2018 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 Pfam PF00293 NUDIX domain 3 130 6.0E-23 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 PRINTS PR01402 Mutator MutX protein signature 101 121 2.6E-56 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 PRINTS PR01402 Mutator MutX protein signature 138 158 2.6E-56 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 PRINTS PR01402 Mutator MutX protein signature 68 94 2.6E-56 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 PRINTS PR01402 Mutator MutX protein signature 22 37 2.6E-56 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 PRINTS PR01402 Mutator MutX protein signature 121 138 2.6E-56 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 PRINTS PR01402 Mutator MutX protein signature 4 22 2.6E-56 T 29-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPSF3K_RS08075 1befe0723dd2d2f48e9b9f5d427634f4 160 SUPERFAMILY SSF55811 5 137 2.84E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPSF3K_RS05320 e089a5395208d251031006c3facfc333 303 PIRSF PIRSF000535 1 302 5.4E-87 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPSF3K_RS05320 e089a5395208d251031006c3facfc333 303 SUPERFAMILY SSF53613 1 281 4.83E-67 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS05320 e089a5395208d251031006c3facfc333 303 Pfam PF00294 pfkB family carbohydrate kinase 12 277 2.9E-50 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SPSF3K_RS05320 e089a5395208d251031006c3facfc333 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 1.7E-113 T 29-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 SPSF3K_RS05320 e089a5395208d251031006c3facfc333 303 Gene3D G3DSA:2.20.150.10 9 43 1.4E-16 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain SPSF3K_RS05320 e089a5395208d251031006c3facfc333 303 Gene3D G3DSA:3.40.1190.20 44 302 7.0E-38 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS05320 e089a5395208d251031006c3facfc333 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SPSF3K_RS05320 e089a5395208d251031006c3facfc333 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SPSF3K_RS05320 e089a5395208d251031006c3facfc333 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 5.5E-112 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPSF3K_RS02695 abd53658fbae5c9f2c44f44ccfe4b25e 183 SUPERFAMILY SSF47413 4 65 1.44E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS02695 abd53658fbae5c9f2c44f44ccfe4b25e 183 SMART SM00530 4 59 2.1E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS02695 abd53658fbae5c9f2c44f44ccfe4b25e 183 Pfam PF01381 Helix-turn-helix 12 59 1.3E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS02695 abd53658fbae5c9f2c44f44ccfe4b25e 183 Gene3D G3DSA:1.10.260.40 1 176 1.5E-11 T 29-03-2018 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 Gene3D G3DSA:3.40.1160.10 2 315 1.1E-56 T 29-03-2018 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 SUPERFAMILY SSF53633 4 313 4.71E-87 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 Pfam PF00696 Amino acid kinase family 5 288 7.2E-31 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 TIGRFAM TIGR00746 arcC: carbamate kinase 5 314 5.8E-130 T 29-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 PRINTS PR01469 Bacterial carbamate kinase signature 159 178 1.3E-63 T 29-03-2018 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 1.3E-63 T 29-03-2018 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 PRINTS PR01469 Bacterial carbamate kinase signature 182 200 1.3E-63 T 29-03-2018 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 1.3E-63 T 29-03-2018 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 1.3E-63 T 29-03-2018 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 1.3E-63 T 29-03-2018 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 PRINTS PR01469 Bacterial carbamate kinase signature 110 129 1.3E-63 T 29-03-2018 SPSF3K_RS09055 9f7bec05ed06899a15217f56a2d262cd 316 PIRSF PIRSF000723 2 315 4.9E-122 T 29-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 SUPERFAMILY SSF53807 20 308 3.29E-71 T 29-03-2018 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00690 Adhesin family signature 35 53 3.2E-14 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00690 Adhesin family signature 65 78 3.2E-14 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00690 Adhesin family signature 198 219 3.2E-14 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00690 Adhesin family signature 251 269 3.2E-14 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00690 Adhesin family signature 78 95 3.2E-14 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00691 Adhesin B signature 224 242 8.1E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00691 Adhesin B signature 35 56 8.1E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00691 Adhesin B signature 198 215 8.1E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00691 Adhesin B signature 142 161 8.1E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00691 Adhesin B signature 78 97 8.1E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 PRINTS PR00691 Adhesin B signature 247 264 8.1E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 Gene3D G3DSA:3.40.50.1980 193 309 4.4E-33 T 29-03-2018 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 Pfam PF01297 Zinc-uptake complex component A periplasmic 38 306 8.6E-64 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SPSF3K_RS06435 20c87c8faccb3b2c7d12e63a8834c478 309 Gene3D G3DSA:3.40.50.1980 24 192 4.0E-39 T 29-03-2018 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 49.736 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 Gene3D G3DSA:2.40.30.20 3 82 2.1E-34 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 494 1.2E-48 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.8E-70 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 SUPERFAMILY SSF50615 10 94 3.14E-28 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 SUPERFAMILY SSF47917 372 497 7.59E-49 T 29-03-2018 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 Gene3D G3DSA:3.40.50.300 83 364 8.8E-115 T 29-03-2018 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 SUPERFAMILY SSF52540 95 370 8.35E-96 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 92 6.1E-17 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 Gene3D G3DSA:1.20.150.20 373 498 3.0E-51 T 29-03-2018 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 497 2.0E-247 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04900 bccb2dc87ffec357c55c5f1bc3a47f7d 501 PIRSF PIRSF039088 1 501 3.5E-239 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS03665 be075b34867edf5e4f371050d62e8117 210 Gene3D G3DSA:3.20.20.380 1 209 3.6E-65 T 29-03-2018 SPSF3K_RS03665 be075b34867edf5e4f371050d62e8117 210 Pfam PF03932 CutC family 3 209 5.5E-77 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SPSF3K_RS03665 be075b34867edf5e4f371050d62e8117 210 SUPERFAMILY SSF110395 3 210 4.45E-54 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 SPSF3K_RS02015 cfb1594bdaa319ebbfd06a1a9940dbbf 208 Gene3D G3DSA:2.40.50.140 91 203 1.1E-31 T 29-03-2018 SPSF3K_RS02015 cfb1594bdaa319ebbfd06a1a9940dbbf 208 Gene3D G3DSA:3.30.1940.10 23 90 5.0E-24 T 29-03-2018 IPR027855 Domain of unknown function DUF4479 SPSF3K_RS02015 cfb1594bdaa319ebbfd06a1a9940dbbf 208 Pfam PF14794 Domain of unknown function (DUF4479) 23 89 1.7E-24 T 29-03-2018 IPR027855 Domain of unknown function DUF4479 SPSF3K_RS02015 cfb1594bdaa319ebbfd06a1a9940dbbf 208 SUPERFAMILY SSF50249 96 200 1.74E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS02015 cfb1594bdaa319ebbfd06a1a9940dbbf 208 Pfam PF01588 Putative tRNA binding domain 96 198 4.3E-18 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 SPSF3K_RS06965 ac6d0f7c10546ad0f62b782b022a67ed 556 SUPERFAMILY SSF52540 4 554 1.36E-242 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06965 ac6d0f7c10546ad0f62b782b022a67ed 556 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 328 339 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SPSF3K_RS06965 ac6d0f7c10546ad0f62b782b022a67ed 556 Gene3D G3DSA:3.40.50.300 12 237 1.9E-93 T 29-03-2018 SPSF3K_RS06965 ac6d0f7c10546ad0f62b782b022a67ed 556 Gene3D G3DSA:3.40.50.300 238 442 1.6E-68 T 29-03-2018 SPSF3K_RS06965 ac6d0f7c10546ad0f62b782b022a67ed 556 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 556 48.958 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SPSF3K_RS06965 ac6d0f7c10546ad0f62b782b022a67ed 556 Pfam PF01268 Formate--tetrahydrofolate ligase 2 556 3.6E-264 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SPSF3K_RS06965 ac6d0f7c10546ad0f62b782b022a67ed 556 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SPSF3K_RS06965 ac6d0f7c10546ad0f62b782b022a67ed 556 Gene3D G3DSA:3.10.410.10 444 532 1.6E-37 T 29-03-2018 SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 SUPERFAMILY SSF52540 185 510 1.24E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 SMART SM00382 344 494 8.6E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 Gene3D G3DSA:3.40.50.300 502 719 4.2E-30 T 29-03-2018 SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 5 731 2.8E-280 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 Pfam PF13538 UvrD-like helicase C-terminal domain 659 705 3.7E-17 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 2 749 28.241 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 Gene3D G3DSA:3.40.50.300 288 501 3.1E-37 T 29-03-2018 SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 Pfam PF14490 Helix-hairpin-helix containing domain 146 236 9.0E-27 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 Gene3D G3DSA:1.10.150.20 201 287 0.5 T 29-03-2018 SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 SUPERFAMILY SSF52540 552 730 1.53E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 SUPERFAMILY SSF52540 447 513 1.53E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 Gene3D G3DSA:1.10.150.280 93 200 1.6E-6 T 29-03-2018 SPSF3K_RS01580 7deda4c05e00ffc559ca564f97d44077 800 Pfam PF13604 AAA domain 331 519 3.4E-43 T 29-03-2018 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 SUPERFAMILY SSF51905 2 205 1.3E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 323 1.8E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 301 2.1E-6 T 29-03-2018 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 2.1E-6 T 29-03-2018 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.1E-6 T 29-03-2018 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 SUPERFAMILY SSF51905 149 336 1.9E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 Gene3D G3DSA:3.50.50.60 1 151 2.0E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 Gene3D G3DSA:3.50.50.60 152 356 3.0E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 301 2.7E-8 T 29-03-2018 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 2.7E-8 T 29-03-2018 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 2.7E-8 T 29-03-2018 SPSF3K_RS01860 910540eb349fe1b7ff8628872168735e 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.7E-8 T 29-03-2018 SPSF3K_RS03615 2c382e4d618624295313ba53bfd71d3f 317 Gene3D G3DSA:1.10.3470.10 22 298 1.1E-34 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS03615 2c382e4d618624295313ba53bfd71d3f 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 290 7.1E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 427 436 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 2.7E-11 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 SUPERFAMILY SSF47917 452 535 3.92E-24 T 29-03-2018 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 213 436 7.2E-95 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 SUPERFAMILY SSF50615 2 71 1.7E-11 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 Gene3D G3DSA:3.40.50.300 178 436 3.6E-101 T 29-03-2018 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 204 1.2E-39 T 29-03-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 SUPERFAMILY SSF52540 183 440 8.24E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 Gene3D G3DSA:1.10.1140.10 448 589 4.8E-29 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 589 49.734 T 29-03-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04800 f7aff26b547cbd5eb99d97412db3da2f 591 Gene3D G3DSA:2.40.50.100 116 177 3.8E-20 T 29-03-2018 SPSF3K_RS05965 294fdeffc9d4e129add5cb059ef9519f 171 Hamap MF_01556 Galactose-6-phosphate isomerase subunit LacB [lacB]. 1 171 44.908 T 29-03-2018 IPR004784 Galactose-6-phosphate isomerase subunit LacB GO:0005990|GO:0016861|GO:0050044 KEGG: 00052+5.3.1.26 SPSF3K_RS05965 294fdeffc9d4e129add5cb059ef9519f 171 PIRSF PIRSF005384 1 148 9.5E-49 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS05965 294fdeffc9d4e129add5cb059ef9519f 171 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 144 5.5E-36 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS05965 294fdeffc9d4e129add5cb059ef9519f 171 SUPERFAMILY SSF89623 1 151 6.54E-48 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS05965 294fdeffc9d4e129add5cb059ef9519f 171 Gene3D G3DSA:3.40.1400.10 1 171 7.0E-53 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS05965 294fdeffc9d4e129add5cb059ef9519f 171 Pfam PF02502 Ribose/Galactose Isomerase 3 141 3.0E-41 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 SPSF3K_RS00525 e042bf9f3709e8f1732ec07784bd3a41 204 SUPERFAMILY SSF102114 34 131 2.75E-7 T 29-03-2018 SPSF3K_RS00525 e042bf9f3709e8f1732ec07784bd3a41 204 Pfam PF13353 4Fe-4S single cluster domain 33 171 5.0E-52 T 29-03-2018 SPSF3K_RS00525 e042bf9f3709e8f1732ec07784bd3a41 204 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 24 174 1.2E-60 T 29-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 SPSF3K_RS00525 e042bf9f3709e8f1732ec07784bd3a41 204 PIRSF PIRSF000368 14 188 8.0E-71 T 29-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 SPSF3K_RS00525 e042bf9f3709e8f1732ec07784bd3a41 204 Gene3D G3DSA:3.80.30.10 83 186 6.1E-13 T 29-03-2018 SPSF3K_RS04520 7843f9b71962dfe704c3699f72aba82b 230 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS04520 7843f9b71962dfe704c3699f72aba82b 230 Gene3D G3DSA:3.40.50.300 1 228 1.2E-65 T 29-03-2018 SPSF3K_RS04520 7843f9b71962dfe704c3699f72aba82b 230 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 3 216 1.3E-89 T 29-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 SPSF3K_RS04520 7843f9b71962dfe704c3699f72aba82b 230 Pfam PF00005 ABC transporter 20 167 1.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS04520 7843f9b71962dfe704c3699f72aba82b 230 SMART SM00382 29 223 1.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS04520 7843f9b71962dfe704c3699f72aba82b 230 SUPERFAMILY SSF52540 3 225 8.4E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02230 510f5507f0b5b0b051756e974b86ae97 112 Pfam PF01381 Helix-turn-helix 14 67 1.1E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS02230 510f5507f0b5b0b051756e974b86ae97 112 SUPERFAMILY SSF47413 7 70 9.01E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS02230 510f5507f0b5b0b051756e974b86ae97 112 SMART SM00530 13 68 8.2E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS02230 510f5507f0b5b0b051756e974b86ae97 112 Gene3D G3DSA:1.10.260.40 9 105 9.4E-17 T 29-03-2018 SPSF3K_RS02145 b1ba0a2956641ba99bfd4038e712f8a0 435 Pfam PF13416 Bacterial extracellular solute-binding protein 56 367 1.3E-37 T 29-03-2018 SPSF3K_RS02145 b1ba0a2956641ba99bfd4038e712f8a0 435 Gene3D G3DSA:3.40.190.10 203 388 1.6E-10 T 29-03-2018 SPSF3K_RS02145 b1ba0a2956641ba99bfd4038e712f8a0 435 SUPERFAMILY SSF53850 35 429 2.39E-57 T 29-03-2018 SPSF3K_RS02145 b1ba0a2956641ba99bfd4038e712f8a0 435 Gene3D G3DSA:3.40.190.10 22 201 2.5E-33 T 29-03-2018 SPSF3K_RS04760 ec81561d8bd850f9ce20d5ee54f95c67 119 SUPERFAMILY SSF55298 3 117 3.77E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS04760 ec81561d8bd850f9ce20d5ee54f95c67 119 Gene3D G3DSA:3.30.1330.40 1 118 4.0E-32 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS04760 ec81561d8bd850f9ce20d5ee54f95c67 119 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 116 1.2E-33 T 29-03-2018 IPR006056 RidA family SPSF3K_RS04760 ec81561d8bd850f9ce20d5ee54f95c67 119 Pfam PF01042 Endoribonuclease L-PSP 4 116 9.0E-28 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family SPSF3K_RS08230 34c55ce46e5704ac443eefb9f651c686 453 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 235 439 1.0E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS08230 34c55ce46e5704ac443eefb9f651c686 453 SUPERFAMILY SSF161098 200 439 3.66E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS08230 34c55ce46e5704ac443eefb9f651c686 453 SUPERFAMILY SSF160964 158 199 5.49E-5 T 29-03-2018 SPSF3K_RS08230 34c55ce46e5704ac443eefb9f651c686 453 Gene3D G3DSA:1.10.3720.10 154 449 2.9E-52 T 29-03-2018 SPSF3K_RS10905 2157c70522daad20d3542682dd49fd6a 65 PIRSF PIRSF037263 1 65 2.7E-29 T 29-03-2018 IPR009296 Protein of unknown function DUF951 SPSF3K_RS10905 2157c70522daad20d3542682dd49fd6a 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 2 62 5.0E-26 T 29-03-2018 IPR009296 Protein of unknown function DUF951 SPSF3K_RS08685 4166885822ce054fe02e5cab25889ab4 256 Gene3D G3DSA:3.40.50.150 32 214 6.0E-30 T 29-03-2018 SPSF3K_RS08685 4166885822ce054fe02e5cab25889ab4 256 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 120 126 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SPSF3K_RS08685 4166885822ce054fe02e5cab25889ab4 256 SUPERFAMILY SSF53335 16 201 4.85E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS08685 4166885822ce054fe02e5cab25889ab4 256 Pfam PF05175 Methyltransferase small domain 21 173 3.4E-10 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SPSF3K_RS05265 7afec4f1c3537c06d76ff821ef06a3b9 79 Gene3D G3DSA:3.30.300.20 1 78 8.0E-13 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS05265 7afec4f1c3537c06d76ff821ef06a3b9 79 Hamap MF_00088 UPF0109 protein . 4 77 16.18 T 29-03-2018 IPR020627 Uncharacterised protein family UPF0109 SPSF3K_RS05265 7afec4f1c3537c06d76ff821ef06a3b9 79 Pfam PF13083 KH domain 6 76 1.0E-16 T 29-03-2018 SPSF3K_RS08115 76abc82fb57d4776dffb8bddb656616f 262 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 249 2.7E-58 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SPSF3K_RS08115 76abc82fb57d4776dffb8bddb656616f 262 Gene3D G3DSA:3.40.1390.30 112 224 7.7E-36 T 29-03-2018 SPSF3K_RS08115 76abc82fb57d4776dffb8bddb656616f 262 Gene3D G3DSA:3.40.1390.30 1 111 2.2E-30 T 29-03-2018 SPSF3K_RS08115 76abc82fb57d4776dffb8bddb656616f 262 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 240 2.6E-69 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SPSF3K_RS08115 76abc82fb57d4776dffb8bddb656616f 262 SUPERFAMILY SSF102705 1 261 2.62E-80 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SPSF3K_RS01395 7d1b07cf4bc830a259e255930899b989 452 Pfam PF03600 Citrate transporter 21 398 2.4E-33 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 SPSF3K_RS01395 7d1b07cf4bc830a259e255930899b989 452 TIGRFAM TIGR00784 citMHS: citrate transporter 1 452 1.1E-119 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 18 341 1.7E-161 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 SMART SM00382 71 242 1.7E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 PRINTS PR00142 RecA protein signature 179 208 4.9E-81 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 PRINTS PR00142 RecA protein signature 107 136 4.9E-81 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 PRINTS PR00142 RecA protein signature 224 252 4.9E-81 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 PRINTS PR00142 RecA protein signature 141 170 4.9E-81 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 PRINTS PR00142 RecA protein signature 261 290 4.9E-81 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 PRINTS PR00142 RecA protein signature 315 332 4.9E-81 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 Gene3D G3DSA:3.40.50.300 40 286 1.4E-40 T 29-03-2018 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 Hamap MF_00268 Protein RecA [recA]. 19 347 50.972 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 SUPERFAMILY SSF52540 17 285 9.5E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 SUPERFAMILY SSF54752 286 343 1.07E-19 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 Pfam PF00154 recA bacterial DNA recombination protein 21 286 2.4E-139 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 Gene3D G3DSA:3.30.250.10 287 344 9.9E-24 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal SPSF3K_RS00480 820429e5f8ffbb16d17816415db74c86 379 ProSitePatterns PS00321 recA signature. 227 235 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 SPSF3K_RS03190 54987fc9db7de5e1d14953a2819b62d6 457 SUPERFAMILY SSF53187 371 456 9.02E-48 T 29-03-2018 SPSF3K_RS03190 54987fc9db7de5e1d14953a2819b62d6 457 SUPERFAMILY SSF53187 15 201 9.02E-48 T 29-03-2018 SPSF3K_RS03190 54987fc9db7de5e1d14953a2819b62d6 457 Pfam PF07687 Peptidase dimerisation domain 199 356 5.4E-15 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain SPSF3K_RS03190 54987fc9db7de5e1d14953a2819b62d6 457 Pfam PF01546 Peptidase family M20/M25/M40 86 454 1.3E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SPSF3K_RS03190 54987fc9db7de5e1d14953a2819b62d6 457 Gene3D G3DSA:3.30.70.360 205 370 1.0E-39 T 29-03-2018 SPSF3K_RS03190 54987fc9db7de5e1d14953a2819b62d6 457 Gene3D G3DSA:3.40.630.10 12 204 3.2E-31 T 29-03-2018 SPSF3K_RS02880 f1c7df0dc566679011943bce1172ec41 249 SUPERFAMILY SSF55120 1 249 1.25E-80 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS02880 f1c7df0dc566679011943bce1172ec41 249 Pfam PF01416 tRNA pseudouridine synthase 144 248 1.1E-27 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS02880 f1c7df0dc566679011943bce1172ec41 249 Pfam PF01416 tRNA pseudouridine synthase 6 104 2.0E-10 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS02880 f1c7df0dc566679011943bce1172ec41 249 PIRSF PIRSF001430 1 249 1.4E-74 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS02880 f1c7df0dc566679011943bce1172ec41 249 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 242 8.0E-64 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS02880 f1c7df0dc566679011943bce1172ec41 249 Gene3D G3DSA:3.30.70.580 1 105 8.4E-30 T 29-03-2018 SPSF3K_RS02880 f1c7df0dc566679011943bce1172ec41 249 Gene3D G3DSA:3.30.70.660 107 246 5.2E-39 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS02880 f1c7df0dc566679011943bce1172ec41 249 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 247 34.245 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS02130 9423a648a1fe189c8a712b84f44be0ae 105 SUPERFAMILY SSF103481 4 104 1.44E-20 T 29-03-2018 SPSF3K_RS02130 9423a648a1fe189c8a712b84f44be0ae 105 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.7E-24 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 SPSF3K_RS02930 7ff89aa00d030a12e3b6a90ef74e73b0 242 SMART SM00448 1 112 7.9E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS02930 7ff89aa00d030a12e3b6a90ef74e73b0 242 SUPERFAMILY SSF52172 1 117 2.13E-25 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS02930 7ff89aa00d030a12e3b6a90ef74e73b0 242 Pfam PF04397 LytTr DNA-binding domain 145 240 4.3E-32 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SPSF3K_RS02930 7ff89aa00d030a12e3b6a90ef74e73b0 242 Gene3D G3DSA:3.40.50.2300 1 135 2.2E-23 T 29-03-2018 SPSF3K_RS02930 7ff89aa00d030a12e3b6a90ef74e73b0 242 SMART SM00850 144 241 1.4E-40 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SPSF3K_RS02930 7ff89aa00d030a12e3b6a90ef74e73b0 242 Gene3D G3DSA:2.20.25.10 205 241 5.6E-17 T 29-03-2018 SPSF3K_RS02930 7ff89aa00d030a12e3b6a90ef74e73b0 242 Pfam PF00072 Response regulator receiver domain 3 112 1.9E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS02930 7ff89aa00d030a12e3b6a90ef74e73b0 242 Gene3D G3DSA:2.40.50.40 136 203 5.9E-20 T 29-03-2018 SPSF3K_RS03605 2ad2300e9ad162e108c31011244d9fbb 391 SUPERFAMILY SSF53822 40 383 4.24E-85 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS03605 2ad2300e9ad162e108c31011244d9fbb 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 63 79 1.0E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 SPSF3K_RS03605 2ad2300e9ad162e108c31011244d9fbb 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 41 57 1.0E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 SPSF3K_RS03605 2ad2300e9ad162e108c31011244d9fbb 391 Pfam PF13458 Periplasmic binding protein 40 376 1.8E-61 T 29-03-2018 IPR028081 Leucine-binding protein domain SPSF3K_RS03605 2ad2300e9ad162e108c31011244d9fbb 391 Gene3D G3DSA:3.40.50.2300 196 372 1.1E-30 T 29-03-2018 SPSF3K_RS03605 2ad2300e9ad162e108c31011244d9fbb 391 Gene3D G3DSA:3.40.50.2300 27 195 6.2E-35 T 29-03-2018 SPSF3K_RS11010 22d41937e7a80265517ef8c232dbff00 25 Pfam PF14205 Cysteine-rich KTR 6 25 2.8E-9 T 29-03-2018 IPR025957 Cysteine-rich KTR SPSF3K_RS10930 22d41937e7a80265517ef8c232dbff00 25 Pfam PF14205 Cysteine-rich KTR 6 25 2.8E-9 T 29-03-2018 IPR025957 Cysteine-rich KTR SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 TIGRFAM TIGR00838 argH: argininosuccinate lyase 7 459 8.8E-194 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 Gene3D G3DSA:1.10.275.10 6 110 1.7E-37 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 Pfam PF00206 Lyase 10 304 4.9E-73 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 Gene3D G3DSA:1.20.200.10 111 378 4.1E-91 T 29-03-2018 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 Pfam PF14698 Argininosuccinate lyase C-terminal 367 435 1.1E-22 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 Hamap MF_00006 Argininosuccinate lyase [argH]. 6 457 42.913 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 3.3E-29 T 29-03-2018 IPR000362 Fumarate lyase family SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 3.3E-29 T 29-03-2018 IPR000362 Fumarate lyase family SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 3.3E-29 T 29-03-2018 IPR000362 Fumarate lyase family SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 3.3E-29 T 29-03-2018 IPR000362 Fumarate lyase family SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 Gene3D G3DSA:1.10.40.30 379 436 1.4E-22 T 29-03-2018 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 2.3E-66 T 29-03-2018 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 2.3E-66 T 29-03-2018 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 2.3E-66 T 29-03-2018 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 2.3E-66 T 29-03-2018 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00145 Argininosuccinate lyase family signature 314 333 2.3E-66 T 29-03-2018 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 2.3E-66 T 29-03-2018 SPSF3K_RS01020 eb35af16d1c4e88cc3b8da1167d38165 461 SUPERFAMILY SSF48557 7 456 1.73E-148 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 SPSF3K_RS02260 24795852ae7ff6d19b1c48b9dd95cfb4 169 Pfam PF04978 Protein of unknown function (DUF664) 7 166 3.1E-9 T 29-03-2018 IPR007061 Protein of unknown function DUF664 SPSF3K_RS02260 24795852ae7ff6d19b1c48b9dd95cfb4 169 SUPERFAMILY SSF109854 4 166 1.39E-18 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes SPSF3K_RS02260 24795852ae7ff6d19b1c48b9dd95cfb4 169 Gene3D G3DSA:1.20.120.450 2 169 1.4E-23 T 29-03-2018 SPSF3K_RS04660 78eb66c050932c54ebcd7dbaf6a0a61f 151 SUPERFAMILY SSF52218 4 143 2.26E-37 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS04660 78eb66c050932c54ebcd7dbaf6a0a61f 151 PRINTS PR00369 Flavodoxin signature 53 64 1.2E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SPSF3K_RS04660 78eb66c050932c54ebcd7dbaf6a0a61f 151 PRINTS PR00369 Flavodoxin signature 5 18 1.2E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SPSF3K_RS04660 78eb66c050932c54ebcd7dbaf6a0a61f 151 PRINTS PR00369 Flavodoxin signature 82 92 1.2E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SPSF3K_RS04660 78eb66c050932c54ebcd7dbaf6a0a61f 151 Pfam PF00258 Flavodoxin 6 128 3.2E-21 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 SPSF3K_RS04660 78eb66c050932c54ebcd7dbaf6a0a61f 151 Gene3D G3DSA:3.40.50.360 2 151 1.8E-32 T 29-03-2018 IPR029039 Flavoprotein-like domain SPSF3K_RS04660 78eb66c050932c54ebcd7dbaf6a0a61f 151 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 SPSF3K_RS04660 78eb66c050932c54ebcd7dbaf6a0a61f 151 TIGRFAM TIGR01753 flav_short: flavodoxin 4 142 1.1E-44 T 29-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 SPSF3K_RS05950 a031f9fbc3a08de8fb12974f77ea13d5 148 Gene3D G3DSA:3.40.930.10 1 144 3.0E-31 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS05950 a031f9fbc3a08de8fb12974f77ea13d5 148 SUPERFAMILY SSF55804 2 142 1.28E-34 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS05950 a031f9fbc3a08de8fb12974f77ea13d5 148 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 2 143 9.2E-35 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS05950 a031f9fbc3a08de8fb12974f77ea13d5 148 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 2 126 4.7E-39 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 Gene3D G3DSA:3.40.50.2020 164 293 1.5E-31 T 29-03-2018 SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 Pfam PF14572 Phosphoribosyl synthetase-associated domain 212 316 1.0E-23 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 2.4E-46 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 316 1.6E-102 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 SUPERFAMILY SSF53271 112 308 1.22E-43 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 317 44.4 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 SMART SM01400 10 126 2.4E-74 T 29-03-2018 SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 SUPERFAMILY SSF53271 10 161 1.02E-52 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS06260 2d027937a57b91371ddf9305116479ec 322 Gene3D G3DSA:3.40.50.2020 7 163 4.7E-66 T 29-03-2018 SPSF3K_RS04405 273c0fa50c69b010ab939b3d69215aed 280 Gene3D G3DSA:3.20.20.80 65 280 5.2E-41 T 29-03-2018 SPSF3K_RS04405 273c0fa50c69b010ab939b3d69215aed 280 SUPERFAMILY SSF51445 69 269 7.16E-37 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS04405 273c0fa50c69b010ab939b3d69215aed 280 Pfam PF01183 Glycosyl hydrolases family 25 69 253 5.1E-14 T 29-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 SPSF3K_RS04090 594ef3df8de6d518f278d70a788e1f80 329 Gene3D G3DSA:3.40.50.10440 11 183 2.7E-53 T 29-03-2018 SPSF3K_RS04090 594ef3df8de6d518f278d70a788e1f80 329 Gene3D G3DSA:3.30.1180.20 184 329 3.6E-36 T 29-03-2018 SPSF3K_RS04090 594ef3df8de6d518f278d70a788e1f80 329 SUPERFAMILY SSF82549 11 329 8.63E-99 T 29-03-2018 SPSF3K_RS04090 594ef3df8de6d518f278d70a788e1f80 329 Pfam PF02733 Dak1 domain 18 326 5.4E-88 T 29-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SPSF3K_RS04090 594ef3df8de6d518f278d70a788e1f80 329 TIGRFAM TIGR02362 dhaK1b: probable dihydroxyacetone kinase DhaK1b subunit 3 329 3.9E-158 T 29-03-2018 IPR012735 Dihydroxyacetone kinase DhaK, subunit 1b SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 Pfam PF00106 short chain dehydrogenase 4 190 4.6E-53 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 SUPERFAMILY SSF51735 1 234 5.13E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 Gene3D G3DSA:3.40.50.720 4 239 3.9E-52 T 29-03-2018 SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS06290 a4412017bfe09967e82be28cb548893f 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS08040 78fcb0f74237e96204a66db3e00bb93d 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 271 7.7E-32 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPSF3K_RS08040 78fcb0f74237e96204a66db3e00bb93d 289 Gene3D G3DSA:1.10.3470.10 1 281 2.0E-34 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS06885 ddafb01524dce2e2077b9f0b39c77d01 138 Gene3D G3DSA:1.10.10.10 3 138 2.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06885 ddafb01524dce2e2077b9f0b39c77d01 138 SUPERFAMILY SSF46785 4 137 9.79E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06885 ddafb01524dce2e2077b9f0b39c77d01 138 SMART SM00347 25 123 2.2E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS06885 ddafb01524dce2e2077b9f0b39c77d01 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 2.2E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS06885 ddafb01524dce2e2077b9f0b39c77d01 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 2.2E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS06885 ddafb01524dce2e2077b9f0b39c77d01 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 2.2E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS06885 ddafb01524dce2e2077b9f0b39c77d01 138 Pfam PF01047 MarR family 32 82 3.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS09485 17617a1b7e06375858fc55dbf0d2b449 121 Pfam PF05713 Bacterial mobilisation protein (MobC) 62 105 6.4E-15 T 29-03-2018 IPR008687 Bacterial mobilisation SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 SUPERFAMILY SSF46785 161 230 3.13E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 SUPERFAMILY SSF51206 15 151 4.06E-32 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 Gene3D G3DSA:2.60.120.10 3 154 1.4E-30 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 Gene3D G3DSA:1.10.10.10 155 233 3.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 SMART SM00419 176 225 1.5E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 SMART SM00100 21 143 1.3E-18 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 Pfam PF13545 Crp-like helix-turn-helix domain 161 229 4.0E-15 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 Pfam PF00027 Cyclic nucleotide-binding domain 40 128 7.5E-19 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 198 213 4.3E-8 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS05765 e93ed0ee8c3dee4a3717cd222c7e0908 234 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 182 198 4.3E-8 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS10450 0a32b8b36f0c711c9ef2f03ad6eb8810 132 SUPERFAMILY SSF56047 2 132 3.14E-49 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10450 0a32b8b36f0c711c9ef2f03ad6eb8810 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.827 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10450 0a32b8b36f0c711c9ef2f03ad6eb8810 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10450 0a32b8b36f0c711c9ef2f03ad6eb8810 132 Gene3D G3DSA:3.30.1490.10 69 130 1.2E-23 T 29-03-2018 SPSF3K_RS10450 0a32b8b36f0c711c9ef2f03ad6eb8810 132 Gene3D G3DSA:3.30.1370.30 1 67 8.3E-26 T 29-03-2018 SPSF3K_RS10450 0a32b8b36f0c711c9ef2f03ad6eb8810 132 Pfam PF00410 Ribosomal protein S8 5 132 9.5E-53 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS01560 ce1b136fd39d52f98f2ff7da12763896 145 SUPERFAMILY SSF55729 6 145 7.15E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS01560 ce1b136fd39d52f98f2ff7da12763896 145 Gene3D G3DSA:3.40.630.30 1 145 9.9E-33 T 29-03-2018 SPSF3K_RS01560 ce1b136fd39d52f98f2ff7da12763896 145 Pfam PF13673 Acetyltransferase (GNAT) domain 41 145 4.1E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS08820 78bad7e19f832cc0c0049f658cb40a78 71 Gene3D G3DSA:1.10.287.1040 4 67 8.5E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPSF3K_RS08820 78bad7e19f832cc0c0049f658cb40a78 71 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 48 1.0E-15 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPSF3K_RS08820 78bad7e19f832cc0c0049f658cb40a78 71 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 14.23 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPSF3K_RS08820 78bad7e19f832cc0c0049f658cb40a78 71 SUPERFAMILY SSF116842 4 69 1.96E-18 T 29-03-2018 SPSF3K_RS08820 78bad7e19f832cc0c0049f658cb40a78 71 Pfam PF02609 Exonuclease VII small subunit 7 56 2.0E-18 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPSF3K_RS08820 78bad7e19f832cc0c0049f658cb40a78 71 PIRSF PIRSF006488 1 70 6.2E-19 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPSF3K_RS08820 78bad7e19f832cc0c0049f658cb40a78 71 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 61 1.3E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPSF3K_RS07210 2b95dc0eae1803bab968e2173734d5fa 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 269 1.5E-64 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS07210 2b95dc0eae1803bab968e2173734d5fa 278 Gene3D G3DSA:3.40.190.10 2 166 1.7E-36 T 29-03-2018 SPSF3K_RS07210 2b95dc0eae1803bab968e2173734d5fa 278 Gene3D G3DSA:3.40.190.10 167 278 4.8E-16 T 29-03-2018 SPSF3K_RS07210 2b95dc0eae1803bab968e2173734d5fa 278 SMART SM00062 42 270 1.7E-78 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS07210 2b95dc0eae1803bab968e2173734d5fa 278 SUPERFAMILY SSF53850 4 270 2.03E-70 T 29-03-2018 SPSF3K_RS02625 7542e83fd55266dc4a5bec21307c9dff 89 SMART SM01387 8 88 6.3E-46 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS02625 7542e83fd55266dc4a5bec21307c9dff 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.461 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS02625 7542e83fd55266dc4a5bec21307c9dff 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 8.0E-39 T 29-03-2018 SPSF3K_RS02625 7542e83fd55266dc4a5bec21307c9dff 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 3.3E-36 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS02625 7542e83fd55266dc4a5bec21307c9dff 89 Pfam PF00312 Ribosomal protein S15 8 88 9.4E-34 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS02625 7542e83fd55266dc4a5bec21307c9dff 89 Gene3D G3DSA:1.10.287.10 2 89 2.1E-32 T 29-03-2018 SPSF3K_RS02625 7542e83fd55266dc4a5bec21307c9dff 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS02625 7542e83fd55266dc4a5bec21307c9dff 89 SUPERFAMILY SSF47060 3 89 7.36E-34 T 29-03-2018 IPR009068 S15/NS1, RNA-binding SPSF3K_RS05640 39a4668a18bff7724102e6f5b4fb0dba 228 Pfam PF13610 DDE domain 74 204 5.4E-40 T 29-03-2018 IPR032874 DDE domain SPSF3K_RS05640 39a4668a18bff7724102e6f5b4fb0dba 228 SUPERFAMILY SSF53098 71 186 3.03E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS05640 39a4668a18bff7724102e6f5b4fb0dba 228 Gene3D G3DSA:3.30.420.10 71 208 1.1E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS05640 39a4668a18bff7724102e6f5b4fb0dba 228 Gene3D G3DSA:1.10.10.10 25 70 0.0014 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08315 772b8ac27f1395b7bb7cd440332fc259 43 Pfam PF13253 Protein of unknown function (DUF4044) 8 39 4.6E-16 T 29-03-2018 IPR025270 Protein of unknown function DUF4044 SPSF3K_RS09150 a9ebc312ae6ceb698df47db583f4adf9 911 Gene3D G3DSA:3.90.70.10 761 902 3.8E-14 T 29-03-2018 SPSF3K_RS09150 a9ebc312ae6ceb698df47db583f4adf9 911 Pfam PF08481 GBS Bsp-like repeat 464 521 1.6E-11 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS09150 a9ebc312ae6ceb698df47db583f4adf9 911 Pfam PF08481 GBS Bsp-like repeat 341 428 3.1E-23 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS09150 a9ebc312ae6ceb698df47db583f4adf9 911 Pfam PF08481 GBS Bsp-like repeat 174 223 2.6E-10 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS09150 a9ebc312ae6ceb698df47db583f4adf9 911 Pfam PF08481 GBS Bsp-like repeat 534 615 9.1E-21 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS09150 a9ebc312ae6ceb698df47db583f4adf9 911 Pfam PF08481 GBS Bsp-like repeat 241 322 3.8E-23 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS09150 a9ebc312ae6ceb698df47db583f4adf9 911 Pfam PF08481 GBS Bsp-like repeat 649 725 3.1E-9 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS09150 a9ebc312ae6ceb698df47db583f4adf9 911 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 3 22 4.9E-6 T 29-03-2018 IPR022263 KxYKxGKxW signal peptide SPSF3K_RS05250 955269762f3f5a7771264839c57224a8 407 Pfam PF12704 MacB-like periplasmic core domain 18 218 2.9E-28 T 29-03-2018 IPR025857 MacB-like periplasmic core domain SPSF3K_RS05250 955269762f3f5a7771264839c57224a8 407 Pfam PF02687 FtsX-like permease family 312 400 6.0E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SPSF3K_RS05520 6010526d281eee8b745830a24da0d2ac 788 SUPERFAMILY SSF52540 409 747 1.35E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05520 6010526d281eee8b745830a24da0d2ac 788 Gene3D G3DSA:3.40.50.300 11 764 2.9E-15 T 29-03-2018 SPSF3K_RS05520 6010526d281eee8b745830a24da0d2ac 788 Pfam PF12846 AAA-like domain 445 718 3.4E-8 T 29-03-2018 SPSF3K_RS03755 c26a3e8ce34c579f3ae92a80b8e31fb7 304 SUPERFAMILY SSF144083 235 296 5.49E-11 T 29-03-2018 SPSF3K_RS03755 c26a3e8ce34c579f3ae92a80b8e31fb7 304 SUPERFAMILY SSF143865 15 234 1.57E-23 T 29-03-2018 SPSF3K_RS03755 c26a3e8ce34c579f3ae92a80b8e31fb7 304 Pfam PF01544 CorA-like Mg2+ transporter protein 15 295 1.1E-51 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SPSF3K_RS03755 c26a3e8ce34c579f3ae92a80b8e31fb7 304 Gene3D G3DSA:3.30.460.20 8 117 2.7E-8 T 29-03-2018 SPSF3K_RS03755 c26a3e8ce34c579f3ae92a80b8e31fb7 304 Gene3D G3DSA:1.20.58.340 234 303 4.1E-11 T 29-03-2018 SPSF3K_RS03755 c26a3e8ce34c579f3ae92a80b8e31fb7 304 Gene3D G3DSA:1.20.58.340 118 233 8.5E-6 T 29-03-2018 SPSF3K_RS02270 6d061a10e15c1f1167c2438b2fd5dbf9 162 SUPERFAMILY SSF55826 1 162 3.01E-39 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS02270 6d061a10e15c1f1167c2438b2fd5dbf9 162 Pfam PF04073 Aminoacyl-tRNA editing domain 23 149 3.0E-23 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS02270 6d061a10e15c1f1167c2438b2fd5dbf9 162 Gene3D G3DSA:3.90.960.10 2 162 3.9E-26 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 338 34.568 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 Gene3D G3DSA:1.10.240.10 209 333 2.3E-29 T 29-03-2018 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 Pfam PF00579 tRNA synthetases class I (W and Y) 4 291 1.0E-56 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 337 3.6E-77 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 SUPERFAMILY SSF52374 5 337 8.55E-77 T 29-03-2018 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 4.3E-25 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 4.3E-25 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 4.3E-25 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 147 168 4.3E-25 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 SPSF3K_RS00050 a56b9950fdb23f516c2ef998baa49f48 340 Gene3D G3DSA:3.40.50.620 2 208 4.3E-58 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS10250 565fdc9688d95449302145055c2f5541 266 SUPERFAMILY SSF141868 44 262 2.22E-21 T 29-03-2018 IPR001633 EAL domain SPSF3K_RS10250 565fdc9688d95449302145055c2f5541 266 Pfam PF00563 EAL domain 44 261 4.8E-12 T 29-03-2018 IPR001633 EAL domain SPSF3K_RS10250 565fdc9688d95449302145055c2f5541 266 Gene3D G3DSA:3.20.20.450 37 266 3.5E-17 T 29-03-2018 IPR001633 EAL domain SPSF3K_RS03385 cfec7b4f84d24c2b1d7a5b4ab24d7548 216 Pfam PF01569 PAP2 superfamily 90 206 9.3E-21 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPSF3K_RS03385 cfec7b4f84d24c2b1d7a5b4ab24d7548 216 SMART SM00014 87 199 2.2E-24 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPSF3K_RS03385 cfec7b4f84d24c2b1d7a5b4ab24d7548 216 SUPERFAMILY SSF48317 6 211 3.14E-41 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPSF3K_RS03385 cfec7b4f84d24c2b1d7a5b4ab24d7548 216 Gene3D G3DSA:1.20.144.10 6 215 1.2E-26 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 Gene3D G3DSA:3.40.50.720 1 138 9.4E-33 T 29-03-2018 SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 137 328 5.6E-55 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 118 7.0E-33 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 SUPERFAMILY SSF55347 127 329 1.14E-68 T 29-03-2018 SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 Gene3D G3DSA:3.30.360.10 139 325 1.4E-66 T 29-03-2018 SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 5 342 9.2E-133 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 PIRSF PIRSF000148 2 347 3.5E-123 T 29-03-2018 SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 342 36.743 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 SUPERFAMILY SSF51735 3 155 6.05E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06950 ce692596c3a61dfd48acfe16208f53b5 358 SMART SM00859 4 119 4.8E-43 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 SPSF3K_RS10480 5b4d0db6fb8153aa5c526fbb5e42dc6a 68 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 7 67 16.778 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10480 5b4d0db6fb8153aa5c526fbb5e42dc6a 68 ProSitePatterns PS00579 Ribosomal protein L29 signature. 46 60 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10480 5b4d0db6fb8153aa5c526fbb5e42dc6a 68 SUPERFAMILY SSF46561 11 67 1.01E-19 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10480 5b4d0db6fb8153aa5c526fbb5e42dc6a 68 Pfam PF00831 Ribosomal L29 protein 11 66 4.9E-23 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10480 5b4d0db6fb8153aa5c526fbb5e42dc6a 68 TIGRFAM TIGR00012 L29: ribosomal protein uL29 12 66 1.5E-24 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10480 5b4d0db6fb8153aa5c526fbb5e42dc6a 68 Gene3D G3DSA:1.10.287.310 1 68 4.0E-21 T 29-03-2018 SPSF3K_RS00740 e7fb65b61614c57eeb39c1addafb3a2f 355 Gene3D G3DSA:3.90.1510.10 42 155 4.4E-33 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 SPSF3K_RS00740 e7fb65b61614c57eeb39c1addafb3a2f 355 SUPERFAMILY SSF110738 1 351 1.96E-88 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SPSF3K_RS00740 e7fb65b61614c57eeb39c1addafb3a2f 355 Pfam PF02595 Glycerate kinase family 3 349 9.8E-93 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SPSF3K_RS00740 e7fb65b61614c57eeb39c1addafb3a2f 355 PIRSF PIRSF006078 1 159 3.3E-49 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SPSF3K_RS00740 e7fb65b61614c57eeb39c1addafb3a2f 355 PIRSF PIRSF006078 152 354 1.3E-55 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 SPSF3K_RS00740 e7fb65b61614c57eeb39c1addafb3a2f 355 Gene3D G3DSA:3.40.50.10350 219 354 6.3E-26 T 29-03-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold SPSF3K_RS01915 772ccc6fcf770b6fa043c63c52b231e7 764 Gene3D G3DSA:1.10.3810.10 98 304 2.1E-56 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SPSF3K_RS01915 772ccc6fcf770b6fa043c63c52b231e7 764 SUPERFAMILY SSF53955 77 300 4.5E-56 T 29-03-2018 IPR023346 Lysozyme-like domain SPSF3K_RS01915 772ccc6fcf770b6fa043c63c52b231e7 764 SUPERFAMILY SSF56601 264 280 1.78E-89 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS01915 772ccc6fcf770b6fa043c63c52b231e7 764 SUPERFAMILY SSF56601 334 745 1.78E-89 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS01915 772ccc6fcf770b6fa043c63c52b231e7 764 Pfam PF00905 Penicillin binding protein transpeptidase domain 399 633 4.4E-20 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SPSF3K_RS01915 772ccc6fcf770b6fa043c63c52b231e7 764 Pfam PF00912 Transglycosylase 96 273 4.5E-50 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SPSF3K_RS01915 772ccc6fcf770b6fa043c63c52b231e7 764 Gene3D G3DSA:3.40.710.10 305 722 2.6E-66 T 29-03-2018 SPSF3K_RS04965 5d45f527f20f996b1b9fab41778fe484 357 Pfam PF02687 FtsX-like permease family 269 352 7.3E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SPSF3K_RS05485 8b71c2884e45ca4e130842c4f15baaa5 614 Pfam PF04650 YSIRK type signal peptide 2 22 6.9E-5 T 29-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPSF3K_RS05485 8b71c2884e45ca4e130842c4f15baaa5 614 Pfam PF00746 LPXTG cell wall anchor motif 571 614 1.0E-4 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor SPSF3K_RS08830 852c38dd05caa1800c1318e18c5dc486 280 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 4 278 22.371 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SPSF3K_RS08830 852c38dd05caa1800c1318e18c5dc486 280 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 94 104 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site SPSF3K_RS08830 852c38dd05caa1800c1318e18c5dc486 280 Gene3D G3DSA:3.40.1190.20 1 280 1.2E-41 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS08830 852c38dd05caa1800c1318e18c5dc486 280 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 213 223 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site SPSF3K_RS08830 852c38dd05caa1800c1318e18c5dc486 280 SUPERFAMILY SSF53613 4 275 3.27E-56 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS08830 852c38dd05caa1800c1318e18c5dc486 280 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 5 274 1.3E-51 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SPSF3K_RS08830 852c38dd05caa1800c1318e18c5dc486 280 Pfam PF01256 Carbohydrate kinase 27 271 5.0E-63 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 SPSF3K_RS08425 cb83010acd0c0f43a5e458b68b9b2efd 319 SUPERFAMILY SSF51395 14 316 3.79E-60 T 29-03-2018 SPSF3K_RS08425 cb83010acd0c0f43a5e458b68b9b2efd 319 Gene3D G3DSA:3.20.20.70 11 251 5.4E-38 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS08425 cb83010acd0c0f43a5e458b68b9b2efd 319 Gene3D G3DSA:1.10.1200.80 252 319 1.3E-9 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 SPSF3K_RS08425 cb83010acd0c0f43a5e458b68b9b2efd 319 Pfam PF01207 Dihydrouridine synthase (Dus) 16 312 2.1E-49 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPSF3K_RS08425 cb83010acd0c0f43a5e458b68b9b2efd 319 PIRSF PIRSF006621 3 319 2.2E-81 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPSF3K_RS08425 cb83010acd0c0f43a5e458b68b9b2efd 319 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 100 118 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPSF3K_RS05990 dca9b6895fb82221d85466ecb8e1535c 103 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 10 101 2.3E-32 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 SPSF3K_RS05990 dca9b6895fb82221d85466ecb8e1535c 103 PIRSF PIRSF000699 1 103 1.5E-36 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 SPSF3K_RS05990 dca9b6895fb82221d85466ecb8e1535c 103 Gene3D G3DSA:1.20.58.80 4 102 2.4E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 SPSF3K_RS05990 dca9b6895fb82221d85466ecb8e1535c 103 SUPERFAMILY SSF46973 2 101 1.31E-32 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 SPSF3K_RS03790 6666b546b72540aad86ce313403c8363 230 SUPERFAMILY SSF53167 1 229 1.19E-68 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPSF3K_RS03790 6666b546b72540aad86ce313403c8363 230 Pfam PF01048 Phosphorylase superfamily 2 224 8.0E-45 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPSF3K_RS03790 6666b546b72540aad86ce313403c8363 230 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 228 4.8E-61 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPSF3K_RS03790 6666b546b72540aad86ce313403c8363 230 Gene3D G3DSA:3.40.50.1580 1 230 1.5E-54 T 29-03-2018 SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 SUPERFAMILY SSF52540 4 243 8.04E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 Pfam PF12848 ABC transporter 229 314 4.2E-19 T 29-03-2018 IPR032781 ABC-transporter extension domain SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 SUPERFAMILY SSF52540 308 510 9.55E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 Gene3D G3DSA:3.40.50.300 1 271 9.5E-51 T 29-03-2018 SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 Gene3D G3DSA:3.40.50.300 287 512 5.2E-38 T 29-03-2018 SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 Pfam PF00005 ABC transporter 20 190 3.6E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 Pfam PF00005 ABC transporter 342 469 2.2E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 SMART SM00382 349 514 1.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS06930 7d5aabd33f9fb6a20984cb0b3fe20ed0 514 SMART SM00382 28 238 1.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS06575 39a1397e3d3b4dc128c52d1b08dab729 267 Pfam PF00149 Calcineurin-like phosphoesterase 1 198 2.0E-7 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 SPSF3K_RS06575 39a1397e3d3b4dc128c52d1b08dab729 267 SUPERFAMILY SSF56300 1 127 9.41E-13 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS06575 39a1397e3d3b4dc128c52d1b08dab729 267 SUPERFAMILY SSF56300 171 205 9.41E-13 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS06575 39a1397e3d3b4dc128c52d1b08dab729 267 Gene3D G3DSA:3.60.21.10 1 264 1.5E-12 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 SMART SM00825 Beta-ketoacyl synthase 6 399 8.7E-13 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 PIRSF PIRSF000447 1 410 1.7E-176 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 246 6.4E-54 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 Gene3D G3DSA:3.40.47.10 262 411 3.9E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 5 406 2.4E-167 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 SUPERFAMILY SSF53901 4 251 9.05E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 364 7.5E-31 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 Gene3D G3DSA:3.40.47.10 6 259 5.3E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site SPSF3K_RS10085 1093c1e8925ea81baa53c9e7ecb6d8cc 411 SUPERFAMILY SSF53901 214 408 7.51E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPSF3K_RS04620 8eb6ca01e0a32f5e6f459aaad19cd14a 269 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 7 267 2.8E-82 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 SPSF3K_RS05880 51d46183ec2af38c74f5704fbcc15480 245 SMART SM00650 17 179 7.4E-59 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SPSF3K_RS05880 51d46183ec2af38c74f5704fbcc15480 245 Gene3D G3DSA:3.40.50.150 1 183 9.3E-36 T 29-03-2018 SPSF3K_RS05880 51d46183ec2af38c74f5704fbcc15480 245 Gene3D G3DSA:1.10.8.100 184 242 3.8E-31 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 SPSF3K_RS05880 51d46183ec2af38c74f5704fbcc15480 245 SUPERFAMILY SSF53335 1 238 7.92E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS05880 51d46183ec2af38c74f5704fbcc15480 245 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 239 2.5E-75 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SPSF3K_RS05880 51d46183ec2af38c74f5704fbcc15480 245 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 60 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SPSF3K_RS06455 ff2c18d7072752c43d4765c66356224f 160 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 29-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 SPSF3K_RS06455 ff2c18d7072752c43d4765c66356224f 160 Pfam PF00255 Glutathione peroxidase 4 111 8.0E-39 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SPSF3K_RS06455 ff2c18d7072752c43d4765c66356224f 160 PIRSF PIRSF000303 1 160 7.0E-63 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SPSF3K_RS06455 ff2c18d7072752c43d4765c66356224f 160 SUPERFAMILY SSF52833 3 159 1.68E-58 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS06455 ff2c18d7072752c43d4765c66356224f 160 Gene3D G3DSA:3.40.30.10 2 160 4.8E-50 T 29-03-2018 SPSF3K_RS06455 ff2c18d7072752c43d4765c66356224f 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 29-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 SPSF3K_RS06455 ff2c18d7072752c43d4765c66356224f 160 PRINTS PR01011 Glutathione peroxidase family signature 57 73 2.2E-17 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SPSF3K_RS06455 ff2c18d7072752c43d4765c66356224f 160 PRINTS PR01011 Glutathione peroxidase family signature 122 131 2.2E-17 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SPSF3K_RS06455 ff2c18d7072752c43d4765c66356224f 160 PRINTS PR01011 Glutathione peroxidase family signature 22 39 2.2E-17 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 SPSF3K_RS02510 d121de95faff6c1b1d39e015499e1949 377 SMART SM00382 30 213 3.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02510 d121de95faff6c1b1d39e015499e1949 377 SUPERFAMILY SSF52540 4 256 2.51E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02510 d121de95faff6c1b1d39e015499e1949 377 Gene3D G3DSA:3.40.50.300 1 248 1.3E-69 T 29-03-2018 SPSF3K_RS02510 d121de95faff6c1b1d39e015499e1949 377 Gene3D G3DSA:2.40.50.100 251 305 3.2E-13 T 29-03-2018 SPSF3K_RS02510 d121de95faff6c1b1d39e015499e1949 377 SUPERFAMILY SSF50331 248 376 6.07E-26 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal SPSF3K_RS02510 d121de95faff6c1b1d39e015499e1949 377 Gene3D G3DSA:2.40.50.140 306 361 1.7E-11 T 29-03-2018 SPSF3K_RS02510 d121de95faff6c1b1d39e015499e1949 377 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS02510 d121de95faff6c1b1d39e015499e1949 377 Pfam PF03459 TOBE domain 313 366 6.3E-6 T 29-03-2018 IPR005116 Transport-associated OB, type 1 SPSF3K_RS02510 d121de95faff6c1b1d39e015499e1949 377 Pfam PF00005 ABC transporter 22 163 1.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS09715 5846eb61fbf306aa8837eff22451aa65 172 Hamap MF_01575 UPF0398 protein . 1 171 32.919 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 SPSF3K_RS09715 5846eb61fbf306aa8837eff22451aa65 172 SUPERFAMILY SSF102405 1 171 1.56E-51 T 29-03-2018 SPSF3K_RS09715 5846eb61fbf306aa8837eff22451aa65 172 Gene3D G3DSA:3.40.50.450 1 172 1.1E-24 T 29-03-2018 SPSF3K_RS09715 5846eb61fbf306aa8837eff22451aa65 172 Pfam PF06908 Protein of unknown function (DUF1273) 4 164 2.1E-56 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 SPSF3K_RS09715 5846eb61fbf306aa8837eff22451aa65 172 PIRSF PIRSF021290 1 172 4.3E-61 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 SPSF3K_RS03690 ea98c0a07fb100748ccc030142043934 119 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 108 9.0E-25 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR SPSF3K_RS03690 ea98c0a07fb100748ccc030142043934 119 Pfam PF03960 ArsC family 32 107 1.0E-11 T 29-03-2018 IPR006660 Arsenate reductase-like SPSF3K_RS03690 ea98c0a07fb100748ccc030142043934 119 SUPERFAMILY SSF52833 1 110 7.48E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS03690 ea98c0a07fb100748ccc030142043934 119 Gene3D G3DSA:3.40.30.10 1 113 3.6E-27 T 29-03-2018 SPSF3K_RS02070 c882e7a68b895de642ddb92763b3b0d6 753 Pfam PF04262 Glutamate-cysteine ligase 6 312 6.5E-77 T 29-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SPSF3K_RS02070 c882e7a68b895de642ddb92763b3b0d6 753 Gene3D G3DSA:3.30.1490.20 453 556 2.1E-11 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPSF3K_RS02070 c882e7a68b895de642ddb92763b3b0d6 753 SUPERFAMILY SSF56059 484 617 1.43E-28 T 29-03-2018 SPSF3K_RS02070 c882e7a68b895de642ddb92763b3b0d6 753 SUPERFAMILY SSF56059 653 735 1.43E-28 T 29-03-2018 SPSF3K_RS02070 c882e7a68b895de642ddb92763b3b0d6 753 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 483 581 4.1E-6 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 SPSF3K_RS02070 c882e7a68b895de642ddb92763b3b0d6 753 TIGRFAM TIGR01435 glu_cys_lig_rel: glutamate--cysteine ligase/glutathione synthase 16 742 8.7E-243 T 29-03-2018 IPR006335 Glutathione biosynthesis bifunctional protein GshAB GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SPSF3K_RS02070 c882e7a68b895de642ddb92763b3b0d6 753 Gene3D G3DSA:3.30.470.20 557 736 4.0E-21 T 29-03-2018 SPSF3K_RS02070 c882e7a68b895de642ddb92763b3b0d6 753 Hamap MF_00782 Glutathione biosynthesis bifunctional protein GshAB [gshAB]. 1 753 382.394 T 29-03-2018 IPR006335 Glutathione biosynthesis bifunctional protein GshAB GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255 SPSF3K_RS02070 c882e7a68b895de642ddb92763b3b0d6 753 SUPERFAMILY SSF55931 5 455 3.86E-133 T 29-03-2018 SPSF3K_RS09770 481d927b2c530015ca0e490733b2f3a8 271 Gene3D G3DSA:3.40.190.10 162 271 4.8E-8 T 29-03-2018 SPSF3K_RS09770 481d927b2c530015ca0e490733b2f3a8 271 SMART SM00062 30 265 3.3E-31 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS09770 481d927b2c530015ca0e490733b2f3a8 271 SUPERFAMILY SSF53850 28 265 6.16E-35 T 29-03-2018 SPSF3K_RS09770 481d927b2c530015ca0e490733b2f3a8 271 Gene3D G3DSA:3.40.190.10 27 161 3.5E-22 T 29-03-2018 SPSF3K_RS09770 481d927b2c530015ca0e490733b2f3a8 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 263 5.7E-35 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 Pfam PF00311 Phosphoenolpyruvate carboxylase 129 938 2.6E-253 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 592 604 - T 29-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 SUPERFAMILY SSF51621 17 341 3.61E-285 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 SUPERFAMILY SSF51621 375 938 3.61E-285 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 8 938 17.398 T 29-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 Gene3D G3DSA:1.20.1440.90 273 430 1.4E-27 T 29-03-2018 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 133 146 9.2E-47 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 243 258 9.2E-47 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 767 793 9.2E-47 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 632 661 9.2E-47 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 590 610 9.2E-47 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 186 202 9.2E-47 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS04425 8fb3800f62ceccac621e0c8378d4920b 938 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 134 145 - T 29-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPSF3K_RS02910 594aa48afe21512336393aa20c47441c 226 SUPERFAMILY SSF56784 1 218 2.94E-44 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02910 594aa48afe21512336393aa20c47441c 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 125 188 1.5E-15 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS02910 594aa48afe21512336393aa20c47441c 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 2.9E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS02910 594aa48afe21512336393aa20c47441c 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 150 2.9E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS02910 594aa48afe21512336393aa20c47441c 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 103 116 2.9E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS02910 594aa48afe21512336393aa20c47441c 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 2.9E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS02910 594aa48afe21512336393aa20c47441c 226 Gene3D G3DSA:3.40.50.1000 1 221 3.5E-31 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS02910 594aa48afe21512336393aa20c47441c 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 189 2.3E-31 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS03225 ff30a973e788f6c5c95918eb813518d1 298 Pfam PF01435 Peptidase family M48 84 298 5.9E-37 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SPSF3K_RS03225 ff30a973e788f6c5c95918eb813518d1 298 Gene3D G3DSA:3.30.2010.10 68 161 2.6E-20 T 29-03-2018 SPSF3K_RS03225 ff30a973e788f6c5c95918eb813518d1 298 Hamap MF_00188 Protease HtpX [htpX]. 10 298 26.752 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 SPSF3K_RS02040 387d13d8945764f255f20fd33e848ef4 267 SUPERFAMILY SSF52540 2 238 2.88E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02040 387d13d8945764f255f20fd33e848ef4 267 SMART SM00382 34 229 4.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS02040 387d13d8945764f255f20fd33e848ef4 267 Gene3D G3DSA:3.40.50.300 1 258 2.8E-48 T 29-03-2018 SPSF3K_RS02040 387d13d8945764f255f20fd33e848ef4 267 Pfam PF00005 ABC transporter 25 180 1.6E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS02040 387d13d8945764f255f20fd33e848ef4 267 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS01480 704ae71dcf67fa50e29d8f3688601fe2 49 Gene3D G3DSA:3.40.50.2300 1 49 0.001 T 29-03-2018 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 PRINTS PR00762 Chloride channel signature 83 100 3.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 PRINTS PR00762 Chloride channel signature 384 403 3.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 PRINTS PR00762 Chloride channel signature 366 382 3.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 PRINTS PR00762 Chloride channel signature 331 351 3.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 PRINTS PR00762 Chloride channel signature 163 182 3.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 Pfam PF00654 Voltage gated chloride channel 72 416 4.7E-82 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 Gene3D G3DSA:3.30.70.1450 440 508 9.4E-6 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 Gene3D G3DSA:1.10.3080.10 3 434 2.1E-80 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 SUPERFAMILY SSF116726 443 506 8.63E-5 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPSF3K_RS06160 dbed02a726962d9e412f05cd27c4a47f 511 SUPERFAMILY SSF81340 10 434 5.89E-98 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS01515 ed8a50bd6c2127b2db0bd5bc93ba9e1d 120 Gene3D G3DSA:1.10.3100.10 1 120 2.8E-18 T 29-03-2018 IPR027910 YdiL-like domain SPSF3K_RS01515 ed8a50bd6c2127b2db0bd5bc93ba9e1d 120 Pfam PF01381 Helix-turn-helix 12 67 1.5E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS01515 ed8a50bd6c2127b2db0bd5bc93ba9e1d 120 SUPERFAMILY SSF47413 7 71 2.68E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS01515 ed8a50bd6c2127b2db0bd5bc93ba9e1d 120 SMART SM00530 11 67 2.6E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS06630 d248106079ede1c61db15c6ff0d36bbf 340 Gene3D G3DSA:3.30.360.10 130 339 5.6E-29 T 29-03-2018 SPSF3K_RS06630 d248106079ede1c61db15c6ff0d36bbf 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 132 217 9.8E-7 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SPSF3K_RS06630 d248106079ede1c61db15c6ff0d36bbf 340 Gene3D G3DSA:3.40.50.720 1 129 4.4E-26 T 29-03-2018 SPSF3K_RS06630 d248106079ede1c61db15c6ff0d36bbf 340 SUPERFAMILY SSF55347 125 286 2.18E-19 T 29-03-2018 SPSF3K_RS06630 d248106079ede1c61db15c6ff0d36bbf 340 SUPERFAMILY SSF51735 2 153 2.43E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06630 d248106079ede1c61db15c6ff0d36bbf 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 115 8.8E-17 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SPSF3K_RS04105 00e540f82ec5dffab4793041b629cf0c 191 SUPERFAMILY SSF101473 2 188 8.5E-58 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SPSF3K_RS04105 00e540f82ec5dffab4793041b629cf0c 191 Pfam PF02734 DAK2 domain 30 186 1.2E-48 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SPSF3K_RS04105 00e540f82ec5dffab4793041b629cf0c 191 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 6 186 1.2E-70 T 29-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 SPSF3K_RS04105 00e540f82ec5dffab4793041b629cf0c 191 SMART SM01120 30 187 1.0E-69 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 SPSF3K_RS08910 81949676004c55b4fda81749bdf296a7 223 Pfam PF01168 Alanine racemase, N-terminal domain 29 222 2.8E-15 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 SPSF3K_RS08910 81949676004c55b4fda81749bdf296a7 223 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 223 8.8E-48 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SPSF3K_RS08910 81949676004c55b4fda81749bdf296a7 223 PIRSF PIRSF004848 1 223 6.0E-64 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein SPSF3K_RS08910 81949676004c55b4fda81749bdf296a7 223 SUPERFAMILY SSF51419 1 222 5.5E-67 T 29-03-2018 IPR029066 PLP-binding barrel SPSF3K_RS08910 81949676004c55b4fda81749bdf296a7 223 Gene3D G3DSA:3.20.20.10 1 223 4.7E-49 T 29-03-2018 IPR029066 PLP-binding barrel SPSF3K_RS01980 f8a313be599d66a58fc7258db1eddec2 70 SUPERFAMILY SSF47413 2 64 2.47E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS01980 f8a313be599d66a58fc7258db1eddec2 70 Gene3D G3DSA:1.10.260.40 1 67 3.4E-18 T 29-03-2018 SPSF3K_RS01980 f8a313be599d66a58fc7258db1eddec2 70 SMART SM00530 4 59 2.9E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS01980 f8a313be599d66a58fc7258db1eddec2 70 Pfam PF01381 Helix-turn-helix 5 58 7.1E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 SUPERFAMILY SSF46785 1 87 3.72E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.9E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 Gene3D G3DSA:1.10.10.10 1 92 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 Gene3D G3DSA:3.40.190.10 189 271 3.8E-4 T 29-03-2018 SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 Gene3D G3DSA:3.40.190.10 94 188 6.7E-6 T 29-03-2018 SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 SUPERFAMILY SSF53850 101 296 1.57E-22 T 29-03-2018 SPSF3K_RS07750 534eb6431b19dd18c4bcc762959fb473 300 Pfam PF03466 LysR substrate binding domain 120 297 1.4E-12 T 29-03-2018 IPR005119 LysR, substrate-binding SPSF3K_RS03180 6017cfd0daa7b5737126b11adc94e24c 275 SMART SM00062 36 263 6.0E-50 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS03180 6017cfd0daa7b5737126b11adc94e24c 275 Gene3D G3DSA:3.40.190.10 161 275 5.9E-9 T 29-03-2018 SPSF3K_RS03180 6017cfd0daa7b5737126b11adc94e24c 275 SUPERFAMILY SSF53850 33 263 7.91E-50 T 29-03-2018 SPSF3K_RS03180 6017cfd0daa7b5737126b11adc94e24c 275 Gene3D G3DSA:3.40.190.10 32 160 1.6E-27 T 29-03-2018 SPSF3K_RS03180 6017cfd0daa7b5737126b11adc94e24c 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 261 1.5E-48 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS01810 58b9de17bf6cff2c4e25b219c220ab89 79 Gene3D G3DSA:3.10.450.40 13 78 2.0E-14 T 29-03-2018 SPSF3K_RS01810 58b9de17bf6cff2c4e25b219c220ab89 79 Pfam PF03413 Peptidase propeptide and YPEB domain 14 75 3.8E-11 T 29-03-2018 IPR025711 PepSY domain SPSF3K_RS05020 492415acf94c59f0e132e1f4c0c56484 112 Gene3D G3DSA:3.30.300.130 12 111 1.7E-26 T 29-03-2018 IPR034904 Fe-S cluster assembly domain SPSF3K_RS05020 492415acf94c59f0e132e1f4c0c56484 112 SUPERFAMILY SSF117916 15 110 1.57E-31 T 29-03-2018 IPR034904 Fe-S cluster assembly domain SPSF3K_RS05020 492415acf94c59f0e132e1f4c0c56484 112 Pfam PF01883 Iron-sulfur cluster assembly protein 16 88 1.0E-22 T 29-03-2018 IPR002744 MIP18 family-like SPSF3K_RS03655 9e1a42f3ff29995499641ed0d1a5d04a 289 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 35.358 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS03655 9e1a42f3ff29995499641ed0d1a5d04a 289 Gene3D G3DSA:1.10.10.60 249 289 0.0015 T 29-03-2018 SPSF3K_RS03655 9e1a42f3ff29995499641ed0d1a5d04a 289 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS03655 9e1a42f3ff29995499641ed0d1a5d04a 289 PIRSF PIRSF005917 3 289 1.1E-95 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS03655 9e1a42f3ff29995499641ed0d1a5d04a 289 Gene3D G3DSA:3.30.950.10 124 236 8.0E-36 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SPSF3K_RS03655 9e1a42f3ff29995499641ed0d1a5d04a 289 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 15 287 1.4E-78 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPSF3K_RS03655 9e1a42f3ff29995499641ed0d1a5d04a 289 Gene3D G3DSA:3.40.1010.10 13 123 1.5E-38 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SPSF3K_RS03655 9e1a42f3ff29995499641ed0d1a5d04a 289 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 214 3.3E-20 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SPSF3K_RS03655 9e1a42f3ff29995499641ed0d1a5d04a 289 SUPERFAMILY SSF53790 14 231 3.93E-78 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 SPSF3K_RS05855 da2ead05a159385a7911785e33182df9 175 Gene3D G3DSA:3.40.50.2020 3 169 7.9E-18 T 29-03-2018 SPSF3K_RS05855 da2ead05a159385a7911785e33182df9 175 Pfam PF00156 Phosphoribosyl transferase domain 36 151 4.5E-17 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPSF3K_RS05855 da2ead05a159385a7911785e33182df9 175 SUPERFAMILY SSF53271 15 151 5.24E-26 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS08055 473da1e11ab44c0beb33be1337c5a450 239 SUPERFAMILY SSF117856 6 239 4.81E-70 T 29-03-2018 SPSF3K_RS08055 473da1e11ab44c0beb33be1337c5a450 239 Gene3D G3DSA:3.30.1330.80 98 203 3.4E-39 T 29-03-2018 SPSF3K_RS08055 473da1e11ab44c0beb33be1337c5a450 239 Pfam PF03306 Alpha-acetolactate decarboxylase 7 227 1.4E-72 T 29-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 SPSF3K_RS08055 473da1e11ab44c0beb33be1337c5a450 239 Gene3D G3DSA:3.30.1330.80 4 97 2.2E-29 T 29-03-2018 SPSF3K_RS08055 473da1e11ab44c0beb33be1337c5a450 239 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 6 239 1.7E-77 T 29-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 SPSF3K_RS08055 473da1e11ab44c0beb33be1337c5a450 239 PIRSF PIRSF001332 1 239 1.7E-88 T 29-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 SPSF3K_RS01245 6b04eec96436ffcdd8f76c2671f1741c 347 SMART SM00382 35 233 4.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS01245 6b04eec96436ffcdd8f76c2671f1741c 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 297 1.3E-13 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SPSF3K_RS01245 6b04eec96436ffcdd8f76c2671f1741c 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 3.1E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SPSF3K_RS01245 6b04eec96436ffcdd8f76c2671f1741c 347 Pfam PF00005 ABC transporter 27 183 2.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS01245 6b04eec96436ffcdd8f76c2671f1741c 347 Gene3D G3DSA:3.40.50.300 3 330 6.5E-76 T 29-03-2018 SPSF3K_RS01245 6b04eec96436ffcdd8f76c2671f1741c 347 SUPERFAMILY SSF52540 6 254 9.52E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03795 80205e91e5baf4ee53c90d98218783d0 215 SUPERFAMILY SSF47979 62 135 1.44E-24 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SPSF3K_RS03795 80205e91e5baf4ee53c90d98218783d0 215 Gene3D G3DSA:2.30.30.90 123 214 1.6E-7 T 29-03-2018 SPSF3K_RS03795 80205e91e5baf4ee53c90d98218783d0 215 Gene3D G3DSA:1.10.60.10 72 122 2.2E-20 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SPSF3K_RS03795 80205e91e5baf4ee53c90d98218783d0 215 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 52 1.4E-13 T 29-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 SPSF3K_RS03795 80205e91e5baf4ee53c90d98218783d0 215 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 62 130 1.6E-25 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SPSF3K_RS03795 80205e91e5baf4ee53c90d98218783d0 215 SMART SM00529 23 122 6.8E-31 T 29-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 SPSF3K_RS03795 80205e91e5baf4ee53c90d98218783d0 215 Gene3D G3DSA:1.10.10.10 2 71 1.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03795 80205e91e5baf4ee53c90d98218783d0 215 SUPERFAMILY SSF46785 1 56 2.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07770 33568782eaa05cce5ed4823deb5501f6 135 Pfam PF03960 ArsC family 7 114 3.4E-18 T 29-03-2018 IPR006660 Arsenate reductase-like SPSF3K_RS07770 33568782eaa05cce5ed4823deb5501f6 135 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 8.2E-39 T 29-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 SPSF3K_RS07770 33568782eaa05cce5ed4823deb5501f6 135 Gene3D G3DSA:3.40.30.10 1 134 2.1E-39 T 29-03-2018 SPSF3K_RS07770 33568782eaa05cce5ed4823deb5501f6 135 SUPERFAMILY SSF52833 3 133 1.88E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS03565 c3f0ca9aca61ba3c7d720e519aafa80f 306 Gene3D G3DSA:3.40.50.1980 40 145 3.3E-19 T 29-03-2018 SPSF3K_RS03565 c3f0ca9aca61ba3c7d720e519aafa80f 306 Gene3D G3DSA:3.40.50.1980 146 306 5.7E-28 T 29-03-2018 SPSF3K_RS03565 c3f0ca9aca61ba3c7d720e519aafa80f 306 SUPERFAMILY SSF53807 43 298 2.79E-47 T 29-03-2018 SPSF3K_RS03565 c3f0ca9aca61ba3c7d720e519aafa80f 306 Pfam PF01497 Periplasmic binding protein 54 280 1.4E-26 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 Pfam PF01297 Zinc-uptake complex component A periplasmic 36 306 5.9E-74 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 SUPERFAMILY SSF53807 15 309 1.62E-87 T 29-03-2018 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 Gene3D G3DSA:3.40.50.1980 22 187 7.8E-47 T 29-03-2018 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 Gene3D G3DSA:3.40.50.1980 188 309 8.2E-33 T 29-03-2018 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00690 Adhesin family signature 248 266 5.8E-59 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00690 Adhesin family signature 77 94 5.8E-59 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00690 Adhesin family signature 195 216 5.8E-59 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00690 Adhesin family signature 33 51 5.8E-59 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00690 Adhesin family signature 274 293 5.8E-59 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00690 Adhesin family signature 64 77 5.8E-59 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00691 Adhesin B signature 77 96 1.1E-95 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00691 Adhesin B signature 195 212 1.1E-95 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00691 Adhesin B signature 266 284 1.1E-95 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00691 Adhesin B signature 137 156 1.1E-95 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00691 Adhesin B signature 287 305 1.1E-95 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00691 Adhesin B signature 33 54 1.1E-95 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00691 Adhesin B signature 58 76 1.1E-95 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00691 Adhesin B signature 244 261 1.1E-95 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS03800 2f086d1fbfc8884454ce1794305c88ca 310 PRINTS PR00691 Adhesin B signature 221 239 1.1E-95 T 29-03-2018 IPR006129 Adhesin B GO:0007155 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 Gene3D G3DSA:3.30.1360.40 74 142 3.7E-20 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 Pfam PF01316 Arginine repressor, DNA binding domain 1 66 9.2E-24 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 143 3.8E-50 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 SUPERFAMILY SSF55252 79 142 4.19E-17 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 PRINTS PR01467 Bacterial arginine repressor signature 84 97 2.6E-19 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 PRINTS PR01467 Bacterial arginine repressor signature 114 129 2.6E-19 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.6E-19 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.6E-19 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 SUPERFAMILY SSF46785 1 68 1.29E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 Pfam PF02863 Arginine repressor, C-terminal domain 79 141 8.6E-19 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 Hamap MF_00173 Arginine repressor [argR]. 1 145 53.044 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 Gene3D G3DSA:1.10.10.10 3 66 4.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00335 f47980d130de242430443452df10a1b9 145 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 84 135 1.0E-5 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 SPSF3K_RS04445 7a79edffd1bf0c2cb8bb26fff9a0334c 410 Gene3D G3DSA:3.40.630.30 162 381 4.1E-29 T 29-03-2018 SPSF3K_RS04445 7a79edffd1bf0c2cb8bb26fff9a0334c 410 SUPERFAMILY SSF55729 1 157 4.45E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS04445 7a79edffd1bf0c2cb8bb26fff9a0334c 410 Pfam PF02388 FemAB family 6 404 1.1E-127 T 29-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 SPSF3K_RS04445 7a79edffd1bf0c2cb8bb26fff9a0334c 410 SUPERFAMILY SSF46589 238 300 3.82E-13 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 SPSF3K_RS04445 7a79edffd1bf0c2cb8bb26fff9a0334c 410 SUPERFAMILY SSF55729 161 238 2.47E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS04445 7a79edffd1bf0c2cb8bb26fff9a0334c 410 SUPERFAMILY SSF55729 305 399 2.47E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS04445 7a79edffd1bf0c2cb8bb26fff9a0334c 410 Gene3D G3DSA:3.40.630.30 1 161 6.6E-21 T 29-03-2018 SPSF3K_RS01340 4474bd3a9c297632a3bf9e752cb33a3a 406 SUPERFAMILY SSF55729 8 166 9.0E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS01340 4474bd3a9c297632a3bf9e752cb33a3a 406 Gene3D G3DSA:3.40.630.30 3 172 1.1E-36 T 29-03-2018 SPSF3K_RS01340 4474bd3a9c297632a3bf9e752cb33a3a 406 SUPERFAMILY SSF55729 300 392 2.65E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS01340 4474bd3a9c297632a3bf9e752cb33a3a 406 SUPERFAMILY SSF55729 167 243 2.65E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS01340 4474bd3a9c297632a3bf9e752cb33a3a 406 Pfam PF02388 FemAB family 11 395 2.1E-121 T 29-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 SPSF3K_RS01340 4474bd3a9c297632a3bf9e752cb33a3a 406 Gene3D G3DSA:3.40.630.30 173 374 9.9E-27 T 29-03-2018 SPSF3K_RS10105 ac3952d311f0a1da56fe5b84c2656f37 74 Hamap MF_01217 Acyl carrier protein [acpP]. 2 73 17.749 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SPSF3K_RS10105 ac3952d311f0a1da56fe5b84c2656f37 74 SUPERFAMILY SSF47336 3 72 6.81E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SPSF3K_RS10105 ac3952d311f0a1da56fe5b84c2656f37 74 Gene3D G3DSA:1.10.1200.10 1 74 1.2E-19 T 29-03-2018 SPSF3K_RS10105 ac3952d311f0a1da56fe5b84c2656f37 74 Pfam PF00550 Phosphopantetheine attachment site 5 69 3.0E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain SPSF3K_RS10105 ac3952d311f0a1da56fe5b84c2656f37 74 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 32 72 6.0E-14 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 SPSF3K_RS05215 4e89600e604c1a3bdf9ae69eee9e99d5 418 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 339 359 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SPSF3K_RS05215 4e89600e604c1a3bdf9ae69eee9e99d5 418 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 18 414 1.9E-118 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 SPSF3K_RS05215 4e89600e604c1a3bdf9ae69eee9e99d5 418 Pfam PF00860 Permease family 19 390 3.2E-88 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPSF3K_RS03355 c6f9319355cbe3e1236e79fc7715d701 234 Hamap MF_01805 Segregation and condensation protein A [scpA]. 1 234 25.004 T 29-03-2018 IPR003768 Segregation and condensation protein A SPSF3K_RS03355 c6f9319355cbe3e1236e79fc7715d701 234 Gene3D G3DSA:1.10.10.580 166 232 1.0E-9 T 29-03-2018 SPSF3K_RS03355 c6f9319355cbe3e1236e79fc7715d701 234 Pfam PF02616 Segregation and condensation protein ScpA 18 228 2.5E-25 T 29-03-2018 IPR003768 Segregation and condensation protein A SPSF3K_RS00780 6e31ca4dbe98233658b68ebff1facce1 363 Pfam PF13483 Beta-lactamase superfamily domain 42 290 2.3E-13 T 29-03-2018 SPSF3K_RS00780 6e31ca4dbe98233658b68ebff1facce1 363 Gene3D G3DSA:3.60.15.10 1 346 2.1E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS00780 6e31ca4dbe98233658b68ebff1facce1 363 SUPERFAMILY SSF56281 218 327 2.8E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS00780 6e31ca4dbe98233658b68ebff1facce1 363 SUPERFAMILY SSF56281 165 189 2.8E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS00780 6e31ca4dbe98233658b68ebff1facce1 363 SUPERFAMILY SSF56281 100 134 2.8E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS00780 6e31ca4dbe98233658b68ebff1facce1 363 SUPERFAMILY SSF56281 40 63 2.8E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08005 cfcd2b921e585f92c2bd7a52cb3d36fb 332 SMART SM00861 7 182 1.6E-61 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SPSF3K_RS08005 cfcd2b921e585f92c2bd7a52cb3d36fb 332 Gene3D G3DSA:3.40.50.970 3 197 3.7E-62 T 29-03-2018 SPSF3K_RS08005 cfcd2b921e585f92c2bd7a52cb3d36fb 332 Pfam PF02779 Transketolase, pyrimidine binding domain 7 181 9.3E-46 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SPSF3K_RS08005 cfcd2b921e585f92c2bd7a52cb3d36fb 332 SUPERFAMILY SSF52922 193 327 8.77E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPSF3K_RS08005 cfcd2b921e585f92c2bd7a52cb3d36fb 332 SUPERFAMILY SSF52518 6 196 1.07E-62 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SPSF3K_RS08005 cfcd2b921e585f92c2bd7a52cb3d36fb 332 Pfam PF02780 Transketolase, C-terminal domain 197 320 9.1E-41 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SPSF3K_RS08005 cfcd2b921e585f92c2bd7a52cb3d36fb 332 Gene3D G3DSA:3.40.50.920 198 329 1.1E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 538 3.0E-41 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 328 4.0E-24 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 Gene3D G3DSA:3.40.50.970 1 192 1.9E-47 T 29-03-2018 SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 SUPERFAMILY SSF52518 363 548 5.68E-60 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 Gene3D G3DSA:3.40.50.1220 193 345 1.2E-24 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 173 7.7E-48 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 SUPERFAMILY SSF52467 188 353 2.01E-31 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 9 549 7.9E-273 T 29-03-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 427 446 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 Gene3D G3DSA:3.40.50.970 346 552 6.3E-41 T 29-03-2018 SPSF3K_RS08060 9ae1e7b875db0952318cfcafc5a7a190 558 SUPERFAMILY SSF52518 6 178 1.33E-47 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SPSF3K_RS03310 1ac6a946c972d1e95c7680875fb0c798 171 Gene3D G3DSA:1.10.3210.10 14 169 4.2E-15 T 29-03-2018 SPSF3K_RS03310 1ac6a946c972d1e95c7680875fb0c798 171 SUPERFAMILY SSF109604 15 140 6.28E-19 T 29-03-2018 SPSF3K_RS05145 6da230bffc3a629b9bbaa2c0b9b516a1 112 Hamap MF_01526 UPF0342 protein . 2 112 16.175 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA SPSF3K_RS05145 6da230bffc3a629b9bbaa2c0b9b516a1 112 SUPERFAMILY SSF158622 4 111 1.57E-31 T 29-03-2018 IPR023378 YheA/YmcA-like domain SPSF3K_RS05145 6da230bffc3a629b9bbaa2c0b9b516a1 112 Gene3D G3DSA:1.20.1500.10 4 109 4.5E-27 T 29-03-2018 IPR023378 YheA/YmcA-like domain SPSF3K_RS05145 6da230bffc3a629b9bbaa2c0b9b516a1 112 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 5 108 4.5E-23 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA SPSF3K_RS07365 d4cd95700dc35b0256e63ee6c25aa368 139 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 26 121 7.7E-8 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component SPSF3K_RS07365 d4cd95700dc35b0256e63ee6c25aa368 139 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 14 99 1.0E-4 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component SPSF3K_RS07400 33f15541723bd37fb6776921f2986311 299 Gene3D G3DSA:2.10.110.10 30 140 0.041 T 29-03-2018 SPSF3K_RS07400 33f15541723bd37fb6776921f2986311 299 Gene3D G3DSA:3.40.960.10 195 297 7.4E-8 T 29-03-2018 SPSF3K_RS03555 f3df50c2585b0deb5b66eaa118e616c6 331 Pfam PF01032 FecCD transport family 17 329 4.2E-86 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SPSF3K_RS03555 f3df50c2585b0deb5b66eaa118e616c6 331 Gene3D G3DSA:1.10.3470.10 1 331 9.9E-67 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS03555 f3df50c2585b0deb5b66eaa118e616c6 331 SUPERFAMILY SSF81345 4 329 1.57E-73 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SPSF3K_RS02615 3790dc46a77385fb43aac9dbcc23e32d 306 SUPERFAMILY SSF53067 125 297 1.3E-33 T 29-03-2018 SPSF3K_RS02615 3790dc46a77385fb43aac9dbcc23e32d 306 Gene3D G3DSA:3.30.420.150 123 301 9.6E-35 T 29-03-2018 SPSF3K_RS02615 3790dc46a77385fb43aac9dbcc23e32d 306 Pfam PF02541 Ppx/GppA phosphatase family 17 297 1.2E-47 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 SPSF3K_RS02615 3790dc46a77385fb43aac9dbcc23e32d 306 Gene3D G3DSA:3.30.420.40 1 122 3.0E-27 T 29-03-2018 SPSF3K_RS02615 3790dc46a77385fb43aac9dbcc23e32d 306 SUPERFAMILY SSF53067 3 118 1.55E-24 T 29-03-2018 SPSF3K_RS03515 aea79c1ec7303ac75625973ed927b300 277 Pfam PF00005 ABC transporter 21 159 4.7E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS03515 aea79c1ec7303ac75625973ed927b300 277 SUPERFAMILY SSF52540 4 222 6.71E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03515 aea79c1ec7303ac75625973ed927b300 277 SMART SM00382 30 206 2.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS03515 aea79c1ec7303ac75625973ed927b300 277 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS03515 aea79c1ec7303ac75625973ed927b300 277 Gene3D G3DSA:3.40.50.300 2 263 5.5E-57 T 29-03-2018 SPSF3K_RS00495 75fea405f0c0371410c440c797276ddc 139 SUPERFAMILY SSF53098 1 137 4.25E-43 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS00495 75fea405f0c0371410c440c797276ddc 139 Pfam PF03652 Holliday junction resolvase 1 136 5.9E-44 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SPSF3K_RS00495 75fea405f0c0371410c440c797276ddc 139 SMART SM00732 1 103 1.1E-41 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SPSF3K_RS00495 75fea405f0c0371410c440c797276ddc 139 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 136 2.5E-45 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SPSF3K_RS00495 75fea405f0c0371410c440c797276ddc 139 Gene3D G3DSA:3.30.420.140 1 139 1.2E-44 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 SPSF3K_RS00495 75fea405f0c0371410c440c797276ddc 139 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 139 27.147 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SPSF3K_RS01390 033c925f9558809d96e1b58cb9d8845d 380 SUPERFAMILY SSF54506 172 378 5.34E-58 T 29-03-2018 SPSF3K_RS01390 033c925f9558809d96e1b58cb9d8845d 380 Pfam PF04303 PrpF protein 4 377 2.0E-123 T 29-03-2018 IPR007400 PrpF protein SPSF3K_RS01390 033c925f9558809d96e1b58cb9d8845d 380 Gene3D G3DSA:3.10.310.10 176 360 5.4E-60 T 29-03-2018 SPSF3K_RS01390 033c925f9558809d96e1b58cb9d8845d 380 Gene3D G3DSA:3.10.310.10 1 175 3.2E-73 T 29-03-2018 SPSF3K_RS01390 033c925f9558809d96e1b58cb9d8845d 380 SUPERFAMILY SSF54506 3 167 2.2E-59 T 29-03-2018 SPSF3K_RS07060 8b2be55fdf129cfeb2002b7f26cf674a 252 Gene3D G3DSA:3.40.50.300 1 248 3.0E-60 T 29-03-2018 SPSF3K_RS07060 8b2be55fdf129cfeb2002b7f26cf674a 252 SUPERFAMILY SSF52540 3 239 2.37E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07060 8b2be55fdf129cfeb2002b7f26cf674a 252 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS07060 8b2be55fdf129cfeb2002b7f26cf674a 252 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 6 252 2.6E-118 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 SPSF3K_RS07060 8b2be55fdf129cfeb2002b7f26cf674a 252 SMART SM00382 30 223 2.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS07060 8b2be55fdf129cfeb2002b7f26cf674a 252 Pfam PF00005 ABC transporter 21 177 1.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS09725 bb2f74fc5034f7dd6aec2430aeebc710 740 SUPERFAMILY SSF53955 54 267 3.37E-67 T 29-03-2018 IPR023346 Lysozyme-like domain SPSF3K_RS09725 bb2f74fc5034f7dd6aec2430aeebc710 740 Gene3D G3DSA:3.40.710.10 267 651 3.8E-75 T 29-03-2018 SPSF3K_RS09725 bb2f74fc5034f7dd6aec2430aeebc710 740 Pfam PF00912 Transglycosylase 63 239 1.1E-59 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SPSF3K_RS09725 bb2f74fc5034f7dd6aec2430aeebc710 740 Gene3D G3DSA:1.10.3810.10 55 256 9.0E-72 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 SPSF3K_RS09725 bb2f74fc5034f7dd6aec2430aeebc710 740 Pfam PF00905 Penicillin binding protein transpeptidase domain 335 632 1.9E-30 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SPSF3K_RS09725 bb2f74fc5034f7dd6aec2430aeebc710 740 SUPERFAMILY SSF56601 221 243 6.0E-83 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS09725 bb2f74fc5034f7dd6aec2430aeebc710 740 SUPERFAMILY SSF56601 272 651 6.0E-83 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS09725 bb2f74fc5034f7dd6aec2430aeebc710 740 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 637 1.7E-157 T 29-03-2018 SPSF3K_RS03195 2109565f420cc98bb411807a7bd6f362 354 Gene3D G3DSA:3.40.50.300 1 265 3.6E-75 T 29-03-2018 SPSF3K_RS03195 2109565f420cc98bb411807a7bd6f362 354 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS03195 2109565f420cc98bb411807a7bd6f362 354 Gene3D G3DSA:3.30.70.260 266 352 1.1E-21 T 29-03-2018 SPSF3K_RS03195 2109565f420cc98bb411807a7bd6f362 354 SUPERFAMILY SSF55021 269 351 1.13E-19 T 29-03-2018 SPSF3K_RS03195 2109565f420cc98bb411807a7bd6f362 354 SMART SM00382 34 227 2.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS03195 2109565f420cc98bb411807a7bd6f362 354 SMART SM00930 275 350 1.1E-24 T 29-03-2018 IPR018449 NIL domain SPSF3K_RS03195 2109565f420cc98bb411807a7bd6f362 354 Pfam PF00005 ABC transporter 25 178 7.1E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS03195 2109565f420cc98bb411807a7bd6f362 354 Pfam PF09383 NIL domain 278 348 9.7E-18 T 29-03-2018 IPR018449 NIL domain SPSF3K_RS03195 2109565f420cc98bb411807a7bd6f362 354 SUPERFAMILY SSF52540 5 249 4.33E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04175 66a7d5d8df96d8dfaecfe0ef1e860e6f 275 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 266 8.1E-62 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04175 66a7d5d8df96d8dfaecfe0ef1e860e6f 275 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 266 5.1E-55 T 29-03-2018 IPR000150 Cof family GO:0016787 SPSF3K_RS04175 66a7d5d8df96d8dfaecfe0ef1e860e6f 275 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 8 22 5.3E-5 T 29-03-2018 SPSF3K_RS04175 66a7d5d8df96d8dfaecfe0ef1e860e6f 275 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 219 238 5.3E-5 T 29-03-2018 SPSF3K_RS04175 66a7d5d8df96d8dfaecfe0ef1e860e6f 275 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 242 254 5.3E-5 T 29-03-2018 SPSF3K_RS04175 66a7d5d8df96d8dfaecfe0ef1e860e6f 275 SUPERFAMILY SSF56784 3 271 8.52E-67 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04175 66a7d5d8df96d8dfaecfe0ef1e860e6f 275 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 238 1.8E-31 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 SPSF3K_RS04175 66a7d5d8df96d8dfaecfe0ef1e860e6f 275 Gene3D G3DSA:3.40.50.1000 2 275 5.0E-44 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS00815 8e865029e0cd9a0f866db09fa830cab1 295 Pfam PF06161 Protein of unknown function (DUF975) 1 249 9.5E-47 T 29-03-2018 IPR010380 Protein of unknown function DUF975 SPSF3K_RS09475 daee95dcea2b07835e98987304cbd239 78 SUPERFAMILY SSF140683 1 75 1.22E-19 T 29-03-2018 SPSF3K_RS09475 daee95dcea2b07835e98987304cbd239 78 Pfam PF08984 Domain of unknown function (DUF1858) 5 63 1.7E-16 T 29-03-2018 IPR015077 Domain of unknown function DUF1858 SPSF3K_RS09475 daee95dcea2b07835e98987304cbd239 78 Gene3D G3DSA:1.10.3910.10 4 67 4.4E-13 T 29-03-2018 SPSF3K_RS01770 5b624277fd00b318a9020b833f0d9f9e 260 Pfam PF08222 CodY helix-turn-helix domain 202 260 1.9E-38 T 29-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal SPSF3K_RS01770 5b624277fd00b318a9020b833f0d9f9e 260 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 4 257 1.1E-124 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 SPSF3K_RS01770 5b624277fd00b318a9020b833f0d9f9e 260 Gene3D G3DSA:1.10.10.10 164 260 9.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01770 5b624277fd00b318a9020b833f0d9f9e 260 Gene3D G3DSA:3.30.450.40 1 163 5.5E-29 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS01770 5b624277fd00b318a9020b833f0d9f9e 260 PIRSF PIRSF011572 1 260 6.1E-122 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 SPSF3K_RS01770 5b624277fd00b318a9020b833f0d9f9e 260 Pfam PF06018 CodY GAF-like domain 3 182 4.1E-76 T 29-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 SPSF3K_RS01770 5b624277fd00b318a9020b833f0d9f9e 260 SUPERFAMILY SSF46785 171 259 3.26E-41 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01770 5b624277fd00b318a9020b833f0d9f9e 260 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 260 131.775 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 3.9E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 3.9E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 3.9E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 189 202 3.9E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 6.1E-27 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 SUPERFAMILY SSF56784 3 227 4.41E-47 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 Gene3D G3DSA:3.40.50.1000 91 229 6.4E-35 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 194 4.7E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 Gene3D G3DSA:1.10.150.240 16 90 1.9E-18 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 SPSF3K_RS07820 45ce31e5cb7280bb21867fe05f94b06f 229 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 226 1.3E-59 T 29-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 SPSF3K_RS01610 13c0357cfadc75d4d5e7e20954f72905 104 PRINTS PR00421 Thioredoxin family signature 27 36 9.3E-7 T 29-03-2018 SPSF3K_RS01610 13c0357cfadc75d4d5e7e20954f72905 104 PRINTS PR00421 Thioredoxin family signature 68 79 9.3E-7 T 29-03-2018 SPSF3K_RS01610 13c0357cfadc75d4d5e7e20954f72905 104 PRINTS PR00421 Thioredoxin family signature 19 27 9.3E-7 T 29-03-2018 SPSF3K_RS01610 13c0357cfadc75d4d5e7e20954f72905 104 SUPERFAMILY SSF52833 3 102 5.31E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS01610 13c0357cfadc75d4d5e7e20954f72905 104 ProSitePatterns PS00194 Thioredoxin family active site. 20 38 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 SPSF3K_RS01610 13c0357cfadc75d4d5e7e20954f72905 104 Pfam PF00085 Thioredoxin 3 102 7.0E-29 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SPSF3K_RS01610 13c0357cfadc75d4d5e7e20954f72905 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 6 102 2.2E-34 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SPSF3K_RS01610 13c0357cfadc75d4d5e7e20954f72905 104 PIRSF PIRSF000077 1 104 9.2E-38 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SPSF3K_RS01610 13c0357cfadc75d4d5e7e20954f72905 104 Gene3D G3DSA:3.40.30.10 1 104 3.7E-33 T 29-03-2018 SPSF3K_RS00705 5fe5a747f933ac64993a46899afe7a41 128 SUPERFAMILY SSF55298 8 120 8.75E-23 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS00705 5fe5a747f933ac64993a46899afe7a41 128 Gene3D G3DSA:3.30.1330.40 2 123 7.1E-14 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPSF3K_RS03850 7078421471406634c7b382bdd8259ac1 185 SUPERFAMILY SSF55194 1 185 1.01E-68 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SPSF3K_RS03850 7078421471406634c7b382bdd8259ac1 185 Gene3D G3DSA:1.10.132.20 2 74 7.2E-11 T 29-03-2018 SPSF3K_RS03850 7078421471406634c7b382bdd8259ac1 185 Gene3D G3DSA:1.10.132.20 75 184 7.3E-37 T 29-03-2018 SPSF3K_RS03850 7078421471406634c7b382bdd8259ac1 185 Pfam PF01765 Ribosome recycling factor 20 183 7.2E-64 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 SPSF3K_RS03850 7078421471406634c7b382bdd8259ac1 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.017 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SPSF3K_RS03850 7078421471406634c7b382bdd8259ac1 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 1.2E-71 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 SMART SM00831 9 82 4.6E-25 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 336 342 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 SUPERFAMILY SSF56784 473 726 3.13E-58 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 SUPERFAMILY SSF56784 332 352 3.13E-58 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 185 3.8E-20 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 588 703 2.1E-34 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 219 359 1.7E-26 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 Gene3D G3DSA:1.20.1110.10 643 889 4.1E-68 T 29-03-2018 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 SUPERFAMILY SSF81660 341 521 4.14E-48 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 Pfam PF00122 E1-E2 ATPase 120 314 1.2E-52 T 29-03-2018 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 622 638 1.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 654 679 1.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 476 494 1.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 594 610 1.7E-16 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 636 4.4E-25 T 29-03-2018 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 Pfam PF00690 Cation transporter/ATPase, N-terminus 14 77 8.7E-20 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 SUPERFAMILY SSF81665 234 328 8.63E-128 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 SUPERFAMILY SSF81665 10 123 8.63E-128 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 SUPERFAMILY SSF81665 672 886 8.63E-128 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 Pfam PF00689 Cation transporting ATPase, C-terminus 707 882 2.8E-46 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 Gene3D G3DSA:3.40.50.1000 520 642 4.7E-19 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 SUPERFAMILY SSF81653 122 233 1.24E-29 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 517 528 6.4E-38 T 29-03-2018 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 6.4E-38 T 29-03-2018 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 549 6.4E-38 T 29-03-2018 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 6.4E-38 T 29-03-2018 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 641 6.4E-38 T 29-03-2018 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 646 658 6.4E-38 T 29-03-2018 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 Gene3D G3DSA:3.40.1110.10 295 519 1.6E-49 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 SPSF3K_RS04480 7d389477b061394556b2535fd7e5d032 894 Gene3D G3DSA:2.70.150.10 17 234 6.8E-48 T 29-03-2018 SPSF3K_RS03990 db48417f196f217c40849f8092a87665 155 SUPERFAMILY SSF74982 4 132 4.97E-50 T 29-03-2018 IPR023620 Small protein B SPSF3K_RS03990 db48417f196f217c40849f8092a87665 155 Pfam PF01668 SmpB protein 10 150 4.1E-60 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 SPSF3K_RS03990 db48417f196f217c40849f8092a87665 155 Gene3D G3DSA:2.40.280.10 9 127 6.2E-50 T 29-03-2018 IPR023620 Small protein B SPSF3K_RS03990 db48417f196f217c40849f8092a87665 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 3.1E-56 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 SPSF3K_RS03990 db48417f196f217c40849f8092a87665 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site SPSF3K_RS03990 db48417f196f217c40849f8092a87665 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 132 2.0E-63 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 SPSF3K_RS03990 db48417f196f217c40849f8092a87665 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 69.519 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 SPSF3K_RS04915 3d0c88b9d00203f5181b624efdf7a44b 138 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 85 8.7E-28 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04915 3d0c88b9d00203f5181b624efdf7a44b 138 SUPERFAMILY SSF51344 4 87 1.96E-23 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04915 3d0c88b9d00203f5181b624efdf7a44b 138 SUPERFAMILY SSF46604 90 136 8.11E-5 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04915 3d0c88b9d00203f5181b624efdf7a44b 138 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 20 87 2.0E-26 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04915 3d0c88b9d00203f5181b624efdf7a44b 138 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 135 22.583 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04915 3d0c88b9d00203f5181b624efdf7a44b 138 Gene3D G3DSA:1.20.5.440 92 137 5.4E-15 T 29-03-2018 SPSF3K_RS04915 3d0c88b9d00203f5181b624efdf7a44b 138 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 135 6.4E-14 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04915 3d0c88b9d00203f5181b624efdf7a44b 138 Gene3D G3DSA:2.60.15.10 1 91 3.6E-26 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04915 3d0c88b9d00203f5181b624efdf7a44b 138 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 134 5.9E-31 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS01780 31d361de35d431a01334d138dfbcc65c 86 Pfam PF02583 Metal-sensitive transcriptional repressor 5 83 1.6E-23 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 SUPERFAMILY SSF46557 4 78 3.14E-24 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 PIRSF PIRSF006092 1 160 5.2E-44 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 Pfam PF03449 Transcription elongation factor, N-terminal 7 76 1.0E-26 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 Gene3D G3DSA:3.10.50.30 78 160 8.9E-23 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 SUPERFAMILY SSF54534 83 156 2.22E-18 T 29-03-2018 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 30.715 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 7 156 9.9E-54 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 Gene3D G3DSA:1.10.287.180 5 77 1.3E-27 T 29-03-2018 SPSF3K_RS03290 848c625fcd3735974e7a59990d8043d0 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 3.3E-24 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SPSF3K_RS05780 f760c2b7ab2ebe0f2e0fecfec1d60da1 77 Pfam PF00403 Heavy-metal-associated domain 6 67 2.8E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS05780 f760c2b7ab2ebe0f2e0fecfec1d60da1 77 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SPSF3K_RS05780 f760c2b7ab2ebe0f2e0fecfec1d60da1 77 SUPERFAMILY SSF55008 1 70 1.7E-13 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS05780 f760c2b7ab2ebe0f2e0fecfec1d60da1 77 Gene3D G3DSA:3.30.70.100 1 71 1.5E-14 T 29-03-2018 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 Gene3D G3DSA:3.90.1820.10 1 261 1.5E-57 T 29-03-2018 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 Gene3D G3DSA:3.90.1820.10 262 436 4.2E-50 T 29-03-2018 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 SUPERFAMILY SSF51735 1 165 3.51E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 SUPERFAMILY SSF56327 170 436 1.64E-82 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 194 408 4.3E-46 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 PRINTS PR00732 Glycosyl hydrolase family 4 signature 3 18 1.1E-45 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 PRINTS PR00732 Glycosyl hydrolase family 4 signature 190 202 1.1E-45 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 1.1E-45 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 1.1E-45 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 1.1E-45 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 1.1E-45 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 1.1E-45 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 169 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 SPSF3K_RS06055 281b37a258092e6805f902f059b8810e 457 Pfam PF02056 Family 4 glycosyl hydrolase 3 183 7.4E-65 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 SPSF3K_RS03525 cee001249a1022af617b0bd080bafae0 180 Pfam PF06962 Putative rRNA methylase 43 177 2.3E-48 T 29-03-2018 IPR010719 Putative rRNA methylase SPSF3K_RS03525 cee001249a1022af617b0bd080bafae0 180 SUPERFAMILY SSF53335 7 142 1.22E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS03525 cee001249a1022af617b0bd080bafae0 180 Gene3D G3DSA:3.40.50.150 1 180 3.8E-22 T 29-03-2018 SPSF3K_RS01640 e888d2e1c1401cd8cdde09c7ddf1f693 221 PIRSF PIRSF033111 1 221 1.4E-97 T 29-03-2018 IPR009214 Protein of unknown function DUF1129 SPSF3K_RS01640 e888d2e1c1401cd8cdde09c7ddf1f693 221 Pfam PF06570 Protein of unknown function (DUF1129) 5 214 1.8E-72 T 29-03-2018 IPR009214 Protein of unknown function DUF1129 SPSF3K_RS01640 e888d2e1c1401cd8cdde09c7ddf1f693 221 Gene3D G3DSA:1.10.1900.10 3 80 9.3E-4 T 29-03-2018 SPSF3K_RS04345 27eda4cb7b7cbafb1ee4571872bf2785 557 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 104 114 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SPSF3K_RS04345 27eda4cb7b7cbafb1ee4571872bf2785 557 Pfam PF01268 Formate--tetrahydrofolate ligase 4 557 1.6E-270 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SPSF3K_RS04345 27eda4cb7b7cbafb1ee4571872bf2785 557 Gene3D G3DSA:3.40.50.300 13 238 2.8E-97 T 29-03-2018 SPSF3K_RS04345 27eda4cb7b7cbafb1ee4571872bf2785 557 Gene3D G3DSA:3.40.50.300 239 443 1.0E-73 T 29-03-2018 SPSF3K_RS04345 27eda4cb7b7cbafb1ee4571872bf2785 557 Gene3D G3DSA:3.10.410.10 445 533 1.8E-37 T 29-03-2018 SPSF3K_RS04345 27eda4cb7b7cbafb1ee4571872bf2785 557 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 329 340 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SPSF3K_RS04345 27eda4cb7b7cbafb1ee4571872bf2785 557 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 2 557 49.16 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 SPSF3K_RS04345 27eda4cb7b7cbafb1ee4571872bf2785 557 SUPERFAMILY SSF52540 5 555 2.83E-243 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS06090 a20a894bcb8d2ee5a940fe276523e057 417 Pfam PF02875 Mur ligase family, glutamate ligase domain 294 363 2.3E-6 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS06090 a20a894bcb8d2ee5a940fe276523e057 417 Pfam PF08245 Mur ligase middle domain 44 267 8.5E-11 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS06090 a20a894bcb8d2ee5a940fe276523e057 417 PIRSF PIRSF001563 1 417 1.7E-121 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 SPSF3K_RS06090 a20a894bcb8d2ee5a940fe276523e057 417 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 413 2.1E-117 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 SPSF3K_RS06090 a20a894bcb8d2ee5a940fe276523e057 417 Gene3D G3DSA:3.40.1190.10 1 292 3.2E-69 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS06090 a20a894bcb8d2ee5a940fe276523e057 417 Gene3D G3DSA:3.90.190.20 294 417 2.2E-15 T 29-03-2018 SPSF3K_RS06090 a20a894bcb8d2ee5a940fe276523e057 417 SUPERFAMILY SSF53623 1 292 1.6E-84 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS06090 a20a894bcb8d2ee5a940fe276523e057 417 SUPERFAMILY SSF53244 294 414 6.78E-23 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS03285 8ad9f441e6fd020fc75f4293b19b8452 625 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 267 622 31.246 T 29-03-2018 IPR003770 Endolytic murein transglycosylase SPSF3K_RS03285 8ad9f441e6fd020fc75f4293b19b8452 625 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 261 623 1.5E-72 T 29-03-2018 IPR003770 Endolytic murein transglycosylase SPSF3K_RS03285 8ad9f441e6fd020fc75f4293b19b8452 625 Gene3D G3DSA:3.30.160.60 591 625 1.7E-10 T 29-03-2018 SPSF3K_RS03285 8ad9f441e6fd020fc75f4293b19b8452 625 Pfam PF02618 YceG-like family 299 618 5.0E-75 T 29-03-2018 IPR003770 Endolytic murein transglycosylase SPSF3K_RS03285 8ad9f441e6fd020fc75f4293b19b8452 625 Gene3D G3DSA:1.25.10.10 22 521 5.9E-4 T 29-03-2018 IPR011989 Armadillo-like helical SPSF3K_RS04895 3e328c5efc02eb7be02b55fd56416c6a 178 PRINTS PR00125 ATP synthase delta subunit signature 8 27 5.3E-15 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04895 3e328c5efc02eb7be02b55fd56416c6a 178 PRINTS PR00125 ATP synthase delta subunit signature 137 152 5.3E-15 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04895 3e328c5efc02eb7be02b55fd56416c6a 178 PRINTS PR00125 ATP synthase delta subunit signature 152 170 5.3E-15 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04895 3e328c5efc02eb7be02b55fd56416c6a 178 PRINTS PR00125 ATP synthase delta subunit signature 75 86 5.3E-15 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04895 3e328c5efc02eb7be02b55fd56416c6a 178 SUPERFAMILY SSF47928 6 106 9.29E-16 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04895 3e328c5efc02eb7be02b55fd56416c6a 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 4 178 13.912 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04895 3e328c5efc02eb7be02b55fd56416c6a 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 11 177 2.1E-27 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04895 3e328c5efc02eb7be02b55fd56416c6a 178 Gene3D G3DSA:1.10.520.20 5 108 1.3E-11 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS04895 3e328c5efc02eb7be02b55fd56416c6a 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 10 177 7.7E-32 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 SPSF3K_RS03135 5b5e31b6e83579aae463d3ab0029d3ba 210 SUPERFAMILY SSF52374 23 209 2.1E-50 T 29-03-2018 SPSF3K_RS03135 5b5e31b6e83579aae463d3ab0029d3ba 210 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 24 210 30.191 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SPSF3K_RS03135 5b5e31b6e83579aae463d3ab0029d3ba 210 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 28 209 1.9E-55 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 SPSF3K_RS03135 5b5e31b6e83579aae463d3ab0029d3ba 210 Pfam PF01467 Cytidylyltransferase-like 28 183 1.1E-33 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPSF3K_RS03135 5b5e31b6e83579aae463d3ab0029d3ba 210 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 89 1.1E-7 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPSF3K_RS03135 5b5e31b6e83579aae463d3ab0029d3ba 210 Gene3D G3DSA:3.40.50.620 19 210 8.3E-49 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS10005 222f69021e355629693bfd398b93f267 174 Pfam PF00583 Acetyltransferase (GNAT) family 58 145 2.6E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS10005 222f69021e355629693bfd398b93f267 174 SUPERFAMILY SSF55729 5 173 3.01E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS10005 222f69021e355629693bfd398b93f267 174 Gene3D G3DSA:3.40.630.30 2 173 1.6E-25 T 29-03-2018 SPSF3K_RS02210 f303019b148ae91726c03d1886237c5e 277 Gene3D G3DSA:1.10.3720.10 1 264 1.5E-44 T 29-03-2018 SPSF3K_RS02210 f303019b148ae91726c03d1886237c5e 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 270 2.0E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS02210 f303019b148ae91726c03d1886237c5e 277 SUPERFAMILY SSF161098 4 272 1.12E-69 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS05615 3a2d5a804dcd0dd89c4c8fa36a6f62d3 1025 SUPERFAMILY SSF52540 283 338 5.31E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05615 3a2d5a804dcd0dd89c4c8fa36a6f62d3 1025 SUPERFAMILY SSF52540 631 756 5.31E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05615 3a2d5a804dcd0dd89c4c8fa36a6f62d3 1025 SUPERFAMILY SSF52540 224 450 1.18E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05615 3a2d5a804dcd0dd89c4c8fa36a6f62d3 1025 Gene3D G3DSA:3.40.50.300 257 462 1.0E-26 T 29-03-2018 SPSF3K_RS05615 3a2d5a804dcd0dd89c4c8fa36a6f62d3 1025 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 14 201 4.8E-24 T 29-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 SPSF3K_RS05615 3a2d5a804dcd0dd89c4c8fa36a6f62d3 1025 SMART SM00487 260 478 4.9E-19 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS05615 3a2d5a804dcd0dd89c4c8fa36a6f62d3 1025 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 6 750 2.0E-95 T 29-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 SPSF3K_RS05615 3a2d5a804dcd0dd89c4c8fa36a6f62d3 1025 Pfam PF04851 Type III restriction enzyme, res subunit 262 448 5.3E-39 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SPSF3K_RS08700 8a3306c9ee496aa2cbbc527c383dca49 537 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site SPSF3K_RS08700 8a3306c9ee496aa2cbbc527c383dca49 537 Gene3D G3DSA:3.40.50.300 218 527 1.3E-45 T 29-03-2018 SPSF3K_RS08700 8a3306c9ee496aa2cbbc527c383dca49 537 Gene3D G3DSA:3.40.50.300 5 217 2.5E-60 T 29-03-2018 SPSF3K_RS08700 8a3306c9ee496aa2cbbc527c383dca49 537 Pfam PF00271 Helicase conserved C-terminal domain 226 334 2.6E-28 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS08700 8a3306c9ee496aa2cbbc527c383dca49 537 SMART SM00490 253 334 6.3E-32 T 29-03-2018 IPR001650 Helicase, C-terminal SPSF3K_RS08700 8a3306c9ee496aa2cbbc527c383dca49 537 Pfam PF00270 DEAD/DEAH box helicase 26 190 3.0E-50 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPSF3K_RS08700 8a3306c9ee496aa2cbbc527c383dca49 537 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 1 533 43.964 T 29-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 SPSF3K_RS08700 8a3306c9ee496aa2cbbc527c383dca49 537 SUPERFAMILY SSF52540 71 355 9.34E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08700 8a3306c9ee496aa2cbbc527c383dca49 537 SMART SM00487 20 217 2.4E-63 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 TIGRFAM TIGR00422 valS: valine--tRNA ligase 357 1211 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Gene3D G3DSA:3.40.50.620 782 867 3.6E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 SUPERFAMILY SSF52374 355 545 9.24E-140 T 29-03-2018 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 SUPERFAMILY SSF52374 693 920 9.24E-140 T 29-03-2018 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Pfam PF12787 EcsC protein family 30 316 6.4E-17 T 29-03-2018 IPR024787 EcsC protein SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Gene3D G3DSA:1.10.287.380 1157 1227 7.5E-23 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Gene3D G3DSA:3.90.740.10 543 588 3.2E-13 T 29-03-2018 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 PRINTS PR00986 Valyl-tRNA synthetase signature 389 400 1.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 PRINTS PR00986 Valyl-tRNA synthetase signature 822 840 1.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 PRINTS PR00986 Valyl-tRNA synthetase signature 583 600 1.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 PRINTS PR00986 Valyl-tRNA synthetase signature 790 811 1.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 PRINTS PR00986 Valyl-tRNA synthetase signature 698 711 1.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Hamap MF_02004 Valine--tRNA ligase [valS]. 355 1229 15.697 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 368 910 3.5E-215 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Gene3D G3DSA:3.90.740.10 589 781 3.4E-62 T 29-03-2018 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Pfam PF08264 Anticodon-binding domain of tRNA 960 1104 6.6E-39 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 SUPERFAMILY SSF46589 1164 1227 1.26E-15 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 SUPERFAMILY SSF47323 921 1179 7.1E-65 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 SUPERFAMILY SSF50677 543 694 2.09E-59 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 1164 1229 4.8E-16 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Gene3D G3DSA:3.40.50.620 369 542 1.8E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 396 407 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS09170 2b424d87277330e410806a18e1b7b392 1233 Gene3D G3DSA:1.10.730.10 868 1097 2.0E-70 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 SPSF3K_RS09905 cff30e9fc8e76207560906f39768c642 281 SUPERFAMILY SSF82549 1 279 8.63E-65 T 29-03-2018 SPSF3K_RS09905 cff30e9fc8e76207560906f39768c642 281 Gene3D G3DSA:3.30.1180.10 155 280 3.9E-18 T 29-03-2018 SPSF3K_RS09905 cff30e9fc8e76207560906f39768c642 281 Gene3D G3DSA:3.40.50.10440 56 152 7.6E-28 T 29-03-2018 SPSF3K_RS09905 cff30e9fc8e76207560906f39768c642 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 276 1.1E-55 T 29-03-2018 IPR003797 DegV SPSF3K_RS09905 cff30e9fc8e76207560906f39768c642 281 Gene3D G3DSA:2.20.28.50 29 55 1.3E-13 T 29-03-2018 SPSF3K_RS09905 cff30e9fc8e76207560906f39768c642 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 272 8.0E-65 T 29-03-2018 IPR003797 DegV SPSF3K_RS04300 f8f6535f17c19d4e45fb22ba4f9041ed 70 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 19 66 1.7E-9 T 29-03-2018 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0003713|GO:0006355 SPSF3K_RS04300 f8f6535f17c19d4e45fb22ba4f9041ed 70 PIRSF PIRSF037246 1 70 3.5E-36 T 29-03-2018 IPR017154 Uncharacterised conserved protein UCP037246 SPSF3K_RS01675 de1729b0a1f627770dcd208068c8a18a 143 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 8 141 3.3E-37 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 SPSF3K_RS01675 de1729b0a1f627770dcd208068c8a18a 143 Pfam PF01029 NusB family 11 141 7.2E-34 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPSF3K_RS01675 de1729b0a1f627770dcd208068c8a18a 143 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 7 143 20.832 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 SPSF3K_RS01675 de1729b0a1f627770dcd208068c8a18a 143 SUPERFAMILY SSF48013 8 139 2.62E-34 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPSF3K_RS01675 de1729b0a1f627770dcd208068c8a18a 143 Gene3D G3DSA:1.10.940.10 4 143 7.3E-39 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPSF3K_RS08900 9e4b9ee9da07a03674b6c92602160585 84 Pfam PF02325 YGGT family 11 79 4.6E-16 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 SPSF3K_RS05095 c850b5839c1572d84fb484b2a60bf00a 65 Pfam PF13459 4Fe-4S single cluster domain 8 64 8.8E-9 T 29-03-2018 SPSF3K_RS05095 c850b5839c1572d84fb484b2a60bf00a 65 SUPERFAMILY SSF54862 1 64 1.22E-6 T 29-03-2018 SPSF3K_RS05095 c850b5839c1572d84fb484b2a60bf00a 65 Gene3D G3DSA:3.30.70.20 1 14 0.0097 T 29-03-2018 SPSF3K_RS05095 c850b5839c1572d84fb484b2a60bf00a 65 Gene3D G3DSA:3.30.70.20 15 65 2.2E-7 T 29-03-2018 SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 7.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 7.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 7.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 Gene3D G3DSA:3.40.50.720 5 265 1.0E-59 T 29-03-2018 SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 Pfam PF00106 short chain dehydrogenase 10 198 5.3E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS00860 6c36143fcb331f31ccb0cc81a14cf448 266 SUPERFAMILY SSF51735 9 264 2.33E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS00585 910a31693fe626ef4d8d0b6bf7fa619a 631 Gene3D G3DSA:3.40.390.10 1 291 1.3E-6 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SPSF3K_RS00585 910a31693fe626ef4d8d0b6bf7fa619a 631 Gene3D G3DSA:3.40.390.10 303 631 2.3E-89 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SPSF3K_RS00585 910a31693fe626ef4d8d0b6bf7fa619a 631 Pfam PF01431 Peptidase family M13 438 628 4.6E-61 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPSF3K_RS00585 910a31693fe626ef4d8d0b6bf7fa619a 631 Pfam PF05649 Peptidase family M13 6 384 1.3E-58 T 29-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 SPSF3K_RS00585 910a31693fe626ef4d8d0b6bf7fa619a 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 469 485 2.8E-21 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPSF3K_RS00585 910a31693fe626ef4d8d0b6bf7fa619a 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 539 550 2.8E-21 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPSF3K_RS00585 910a31693fe626ef4d8d0b6bf7fa619a 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 448 460 2.8E-21 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPSF3K_RS00585 910a31693fe626ef4d8d0b6bf7fa619a 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 430 442 2.8E-21 T 29-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPSF3K_RS00585 910a31693fe626ef4d8d0b6bf7fa619a 631 SUPERFAMILY SSF55486 6 631 2.05E-183 T 29-03-2018 SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 6 77 8.0E-35 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 6 81 23.933 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 Pfam PF00366 Ribosomal protein S17 11 78 1.9E-32 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 Gene3D G3DSA:2.40.50.140 6 83 8.3E-31 T 29-03-2018 SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 77 8.5E-35 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 2.2E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 2.2E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 2.2E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 SUPERFAMILY SSF50249 6 83 3.04E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS10475 4ba709ec723e3a9df35186091139e6ee 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 57 69 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 SUPERFAMILY SSF52402 174 388 1.5E-50 T 29-03-2018 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 SUPERFAMILY SSF143437 3 173 1.92E-51 T 29-03-2018 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 404 162.964 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 370 5.7E-63 T 29-03-2018 IPR020536 Thil, AANH domain GO:0004810 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 Pfam PF02926 THUMP domain 48 163 2.4E-15 T 29-03-2018 IPR004114 THUMP domain GO:0003723 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 372 2.2E-115 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 Gene3D G3DSA:3.30.70.1510 5 81 1.1E-23 T 29-03-2018 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 SMART SM00981 74 165 6.1E-20 T 29-03-2018 IPR004114 THUMP domain GO:0003723 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 Gene3D G3DSA:3.30.2300.10 83 162 4.7E-17 T 29-03-2018 SPSF3K_RS05170 f1d61ba7702a3699736c408dead9aa64 404 Gene3D G3DSA:3.40.50.620 175 401 6.8E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS03840 d390d279191f8c9b10dcd3a5df97f726 229 Gene3D G3DSA:3.40.50.790 68 148 5.8E-37 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich SPSF3K_RS03840 d390d279191f8c9b10dcd3a5df97f726 229 SUPERFAMILY SSF56808 6 226 4.97E-82 T 29-03-2018 IPR023674 Ribosomal protein L1-like SPSF3K_RS03840 d390d279191f8c9b10dcd3a5df97f726 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS03840 d390d279191f8c9b10dcd3a5df97f726 229 PIRSF PIRSF002155 1 227 1.5E-76 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS03840 d390d279191f8c9b10dcd3a5df97f726 229 Gene3D G3DSA:3.30.190.20 149 228 1.6E-16 T 29-03-2018 SPSF3K_RS03840 d390d279191f8c9b10dcd3a5df97f726 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.2E-101 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SPSF3K_RS03840 d390d279191f8c9b10dcd3a5df97f726 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.048 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SPSF3K_RS03840 d390d279191f8c9b10dcd3a5df97f726 229 Pfam PF00687 Ribosomal protein L1p/L10e family 32 220 2.4E-50 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein SPSF3K_RS07795 b5c5949905934cb6d582557409b7543c 200 Gene3D G3DSA:3.40.109.10 1 200 8.6E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SPSF3K_RS07795 b5c5949905934cb6d582557409b7543c 200 SUPERFAMILY SSF55469 1 198 3.27E-46 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SPSF3K_RS07795 b5c5949905934cb6d582557409b7543c 200 Pfam PF00881 Nitroreductase family 8 180 2.0E-27 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SPSF3K_RS03380 a2dd89cd4c57c4a4758e2c899148bab5 187 PIRSF PIRSF037778 1 187 4.7E-55 T 29-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 SPSF3K_RS03380 a2dd89cd4c57c4a4758e2c899148bab5 187 Pfam PF12822 ECF transporter, substrate-specific component 5 175 9.5E-20 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 Gene3D G3DSA:2.60.120.260 482 594 1.8E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 Gene3D G3DSA:3.20.20.80 4 331 6.0E-72 T 29-03-2018 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 SUPERFAMILY SSF51445 8 327 2.07E-94 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 SUPERFAMILY SSF49785 445 579 2.83E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 PIRSF PIRSF006336 1 585 6.6E-171 T 29-03-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 Pfam PF01301 Glycosyl hydrolases family 35 9 327 1.8E-109 T 29-03-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 PRINTS PR00742 Glycosyl hydrolase family 35 signature 270 285 2.8E-48 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 PRINTS PR00742 Glycosyl hydrolase family 35 signature 297 313 2.8E-48 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 PRINTS PR00742 Glycosyl hydrolase family 35 signature 34 52 2.8E-48 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 PRINTS PR00742 Glycosyl hydrolase family 35 signature 235 250 2.8E-48 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 PRINTS PR00742 Glycosyl hydrolase family 35 signature 143 158 2.8E-48 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 PRINTS PR00742 Glycosyl hydrolase family 35 signature 529 545 2.8E-48 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 PRINTS PR00742 Glycosyl hydrolase family 35 signature 89 108 2.8E-48 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 PRINTS PR00742 Glycosyl hydrolase family 35 signature 13 30 2.8E-48 T 29-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPSF3K_RS04605 a3fa65ded3943a01b2c1bada611f5cc9 594 Gene3D G3DSA:2.60.120.260 355 481 2.9E-32 T 29-03-2018 IPR008979 Galactose-binding domain-like SPSF3K_RS01220 51ac622c2331f83614cc2ead7d2d8645 123 Pfam PF13411 MerR HTH family regulatory protein 14 76 1.1E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01220 51ac622c2331f83614cc2ead7d2d8645 123 SMART SM00422 13 81 8.2E-21 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01220 51ac622c2331f83614cc2ead7d2d8645 123 SUPERFAMILY SSF46955 13 91 1.19E-18 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS01220 51ac622c2331f83614cc2ead7d2d8645 123 Gene3D G3DSA:1.10.1660.10 2 106 1.1E-21 T 29-03-2018 SPSF3K_RS05835 a894aeecc32323fee1b1e1059f9d99fa 81 Pfam PF07205 Domain of unknown function (DUF1413) 9 76 6.6E-22 T 29-03-2018 IPR010813 Protein of unknown function DUF1413 SPSF3K_RS09960 bf433d939df231c885baccf1c595d4f9 160 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 10 160 21.285 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 SPSF3K_RS09960 bf433d939df231c885baccf1c595d4f9 160 Gene3D G3DSA:2.30.30.180 92 158 2.9E-16 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SPSF3K_RS09960 bf433d939df231c885baccf1c595d4f9 160 SUPERFAMILY SSF74942 89 159 2.09E-17 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SPSF3K_RS09960 bf433d939df231c885baccf1c595d4f9 160 SUPERFAMILY SSF75420 4 88 4.58E-24 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SPSF3K_RS09960 bf433d939df231c885baccf1c595d4f9 160 Pfam PF17384 RimP C-terminal SH3 domain 91 159 8.3E-14 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal SPSF3K_RS09960 bf433d939df231c885baccf1c595d4f9 160 Gene3D G3DSA:3.30.300.70 3 85 3.4E-18 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SPSF3K_RS09960 bf433d939df231c885baccf1c595d4f9 160 Pfam PF02576 RimP N-terminal domain 23 88 1.2E-20 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 Pfam PF12804 MobA-like NTP transferase domain 5 187 2.9E-18 T 29-03-2018 IPR025877 MobA-like NTP transferase SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 260 294 1.9E-4 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 351 8.7E-6 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 450 3.5E-172 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 SUPERFAMILY SSF51161 256 445 3.84E-47 T 29-03-2018 IPR011004 Trimeric LpxA-like SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 SUPERFAMILY SSF53448 4 252 2.82E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 Gene3D G3DSA:2.160.10.10 240 364 3.7E-30 T 29-03-2018 SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 Gene3D G3DSA:3.90.550.10 2 239 6.3E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 Gene3D G3DSA:2.160.10.10 365 451 2.4E-15 T 29-03-2018 SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 394 428 1.1E-7 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS03775 ca42cbb46c7d9fe718d6cffe49f899b8 460 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 451 40.71 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 SPSF3K_RS00190 fb82de4b88a0352801453bb48de40c79 119 Pfam PF06993 Protein of unknown function (DUF1304) 11 116 4.0E-29 T 29-03-2018 IPR009732 Protein of unknown function DUF1304 SPSF3K_RS00320 5c96a24daa9741c20b6e80880ac95c2b 292 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 223 275 1.2E-18 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 SPSF3K_RS00320 5c96a24daa9741c20b6e80880ac95c2b 292 PIRSF PIRSF006483 1 285 1.3E-69 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT SPSF3K_RS00320 5c96a24daa9741c20b6e80880ac95c2b 292 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 12 218 2.2E-51 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 Hamap MF_00456 Glutamate 5-kinase [proB]. 10 267 34.569 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 TIGRFAM TIGR01027 proB: glutamate 5-kinase 10 265 1.2E-81 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 ProSitePatterns PS00902 Glutamate 5-kinase signature. 216 233 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 PIRSF PIRSF000729 5 267 1.3E-84 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 5.8E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 PRINTS PR00474 Glutamate 5-kinase family signature 47 61 5.8E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 PRINTS PR00474 Glutamate 5-kinase family signature 121 142 5.8E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 PRINTS PR00474 Glutamate 5-kinase family signature 218 238 5.8E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 PRINTS PR00474 Glutamate 5-kinase family signature 81 109 5.8E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 SUPERFAMILY SSF53633 10 265 2.49E-65 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 Gene3D G3DSA:3.40.1160.10 1 267 2.9E-55 T 29-03-2018 SPSF3K_RS09805 c82964796e8ea274a639e5d2f15b31f1 267 Pfam PF00696 Amino acid kinase family 10 238 1.2E-35 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase SPSF3K_RS10510 2a3047e865da694399421f91966edeed 98 SUPERFAMILY SSF54189 1 91 1.04E-29 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10510 2a3047e865da694399421f91966edeed 98 Gene3D G3DSA:3.30.70.330 1 97 1.3E-30 T 29-03-2018 SPSF3K_RS10510 2a3047e865da694399421f91966edeed 98 Pfam PF00276 Ribosomal protein L23 5 88 1.4E-29 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10510 2a3047e865da694399421f91966edeed 98 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 29-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10510 2a3047e865da694399421f91966edeed 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 95 21.795 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS06405 06f5d36463309f9e33d73be135c6a48a 176 Pfam PF01872 RibD C-terminal domain 3 165 1.0E-22 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 SPSF3K_RS06405 06f5d36463309f9e33d73be135c6a48a 176 Gene3D G3DSA:3.40.430.10 3 175 5.3E-33 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SPSF3K_RS06405 06f5d36463309f9e33d73be135c6a48a 176 SUPERFAMILY SSF53597 2 174 8.77E-30 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 SPSF3K_RS00730 993c252c479f451ec6515d469f9c7c85 563 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 523 538 4.0E-9 T 29-03-2018 IPR019950 M protein-type anchor domain SPSF3K_RS00730 993c252c479f451ec6515d469f9c7c85 563 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 539 559 4.0E-9 T 29-03-2018 IPR019950 M protein-type anchor domain SPSF3K_RS00730 993c252c479f451ec6515d469f9c7c85 563 Pfam PF00746 LPXTG cell wall anchor motif 522 563 1.7E-7 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor SPSF3K_RS00730 993c252c479f451ec6515d469f9c7c85 563 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 529 561 0.0018 T 29-03-2018 SPSF3K_RS00730 993c252c479f451ec6515d469f9c7c85 563 SUPERFAMILY SSF46997 367 425 9.94E-11 T 29-03-2018 IPR009063 Immunoglobulin/albumin-binding domain GO:0009405 SPSF3K_RS00730 993c252c479f451ec6515d469f9c7c85 563 Gene3D G3DSA:1.10.8.40 302 348 0.0098 T 29-03-2018 SPSF3K_RS00730 993c252c479f451ec6515d469f9c7c85 563 Gene3D G3DSA:1.10.8.40 377 424 6.0E-5 T 29-03-2018 SPSF3K_RS00730 993c252c479f451ec6515d469f9c7c85 563 SUPERFAMILY SSF46997 298 346 1.52E-5 T 29-03-2018 IPR009063 Immunoglobulin/albumin-binding domain GO:0009405 SPSF3K_RS00730 993c252c479f451ec6515d469f9c7c85 563 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 36 1.3E-8 T 29-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPSF3K_RS00460 1c4e037902f072aa7f0a6cb29b969388 407 Gene3D G3DSA:1.20.1250.20 2 201 3.6E-25 T 29-03-2018 SPSF3K_RS00460 1c4e037902f072aa7f0a6cb29b969388 407 Pfam PF07690 Major Facilitator Superfamily 18 368 4.1E-34 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS00460 1c4e037902f072aa7f0a6cb29b969388 407 Gene3D G3DSA:1.20.1250.20 204 406 2.6E-18 T 29-03-2018 SPSF3K_RS00460 1c4e037902f072aa7f0a6cb29b969388 407 SUPERFAMILY SSF103473 18 405 1.26E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS02585 629e1ef164c7a485226d452ba5843674 141 Pfam PF01047 MarR family 35 92 9.2E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS02585 629e1ef164c7a485226d452ba5843674 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 3.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS02585 629e1ef164c7a485226d452ba5843674 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 3.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS02585 629e1ef164c7a485226d452ba5843674 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 3.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS02585 629e1ef164c7a485226d452ba5843674 141 Gene3D G3DSA:1.10.10.10 5 107 5.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02585 629e1ef164c7a485226d452ba5843674 141 SUPERFAMILY SSF46785 12 140 2.14E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02585 629e1ef164c7a485226d452ba5843674 141 SMART SM00347 28 128 2.3E-28 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS02585 629e1ef164c7a485226d452ba5843674 141 Gene3D G3DSA:1.10.287.100 108 141 0.0015 T 29-03-2018 SPSF3K_RS06500 8c8f115febefd659c9e68232c53f121a 490 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 149 161 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 SPSF3K_RS06500 8c8f115febefd659c9e68232c53f121a 490 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 7 487 9.6E-127 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 SPSF3K_RS06500 8c8f115febefd659c9e68232c53f121a 490 SUPERFAMILY SSF103473 13 281 1.4E-21 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS06500 8c8f115febefd659c9e68232c53f121a 490 SUPERFAMILY SSF103473 332 483 1.4E-21 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS06500 8c8f115febefd659c9e68232c53f121a 490 Gene3D G3DSA:1.20.1250.20 282 485 8.0E-10 T 29-03-2018 SPSF3K_RS06500 8c8f115febefd659c9e68232c53f121a 490 Gene3D G3DSA:1.20.1250.20 2 195 2.0E-20 T 29-03-2018 SPSF3K_RS06500 8c8f115febefd659c9e68232c53f121a 490 Pfam PF00854 POT family 87 459 7.1E-67 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 SPSF3K_RS06500 8c8f115febefd659c9e68232c53f121a 490 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 75 99 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 SPSF3K_RS03860 03c03975cef48cdc8ee4931d448cfb33 173 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 164 36.706 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SPSF3K_RS03860 03c03975cef48cdc8ee4931d448cfb33 173 Gene3D G3DSA:3.30.1060.10 1 166 1.1E-66 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SPSF3K_RS03860 03c03975cef48cdc8ee4931d448cfb33 173 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 157 1.9E-63 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SPSF3K_RS03860 03c03975cef48cdc8ee4931d448cfb33 173 SUPERFAMILY SSF55068 3 159 5.89E-71 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SPSF3K_RS03860 03c03975cef48cdc8ee4931d448cfb33 173 Pfam PF01625 Peptide methionine sulfoxide reductase 8 158 7.0E-62 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 SPSF3K_RS00260 e0c2dc19928fb7a04fd0027b2bfe1782 194 Pfam PF01381 Helix-turn-helix 9 61 2.9E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS00260 e0c2dc19928fb7a04fd0027b2bfe1782 194 SMART SM00530 6 61 3.3E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS00260 e0c2dc19928fb7a04fd0027b2bfe1782 194 Gene3D G3DSA:1.10.260.40 1 150 3.2E-20 T 29-03-2018 SPSF3K_RS00260 e0c2dc19928fb7a04fd0027b2bfe1782 194 SUPERFAMILY SSF47413 1 65 1.13E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS03145 a8704786cd69d41ec228c5b5ad8a8432 168 Pfam PF00857 Isochorismatase family 4 136 5.8E-33 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SPSF3K_RS03145 a8704786cd69d41ec228c5b5ad8a8432 168 Gene3D G3DSA:3.40.50.850 1 168 2.0E-36 T 29-03-2018 SPSF3K_RS03145 a8704786cd69d41ec228c5b5ad8a8432 168 SUPERFAMILY SSF52499 2 162 1.44E-40 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SPSF3K_RS04110 af9ca696fc15a776999452e2743087dc 124 SUPERFAMILY SSF53062 4 120 1.11E-33 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPSF3K_RS04110 af9ca696fc15a776999452e2743087dc 124 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 5 118 7.9E-38 T 29-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain SPSF3K_RS04110 af9ca696fc15a776999452e2743087dc 124 Gene3D G3DSA:3.40.50.510 1 122 6.1E-30 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPSF3K_RS04110 af9ca696fc15a776999452e2743087dc 124 Pfam PF03610 PTS system fructose IIA component 5 110 1.7E-25 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPSF3K_RS01930 07202eb1fc5bafa95ff36b3151785ac5 124 Pfam PF06279 Protein of unknown function (DUF1033) 1 118 2.7E-47 T 29-03-2018 IPR010434 Protein of unknown function DUF1033 SPSF3K_RS01425 465a13afe4594ee8554ffa8c448e0703 467 Pfam PF03600 Citrate transporter 14 409 2.2E-46 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 SPSF3K_RS01425 465a13afe4594ee8554ffa8c448e0703 467 TIGRFAM TIGR00784 citMHS: citrate transporter 67 462 6.7E-116 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 SPSF3K_RS07860 fe969dc09e631a45bccdddf4caf505a0 106 SUPERFAMILY SSF69118 10 105 3.01E-29 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SPSF3K_RS07860 fe969dc09e631a45bccdddf4caf505a0 106 Gene3D G3DSA:1.20.1290.10 1 106 7.6E-30 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 SPSF3K_RS07860 fe969dc09e631a45bccdddf4caf505a0 106 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 101 3.4E-23 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SPSF3K_RS00245 af5b424267c0a532ccfd100d0c2e8ce1 512 Pfam PF13193 AMP-binding enzyme C-terminal domain 409 484 1.1E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain SPSF3K_RS00245 af5b424267c0a532ccfd100d0c2e8ce1 512 SUPERFAMILY SSF56801 4 497 2.22E-137 T 29-03-2018 SPSF3K_RS00245 af5b424267c0a532ccfd100d0c2e8ce1 512 Gene3D G3DSA:3.40.50.980 2 160 8.3E-35 T 29-03-2018 SPSF3K_RS00245 af5b424267c0a532ccfd100d0c2e8ce1 512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 29-03-2018 IPR020845 AMP-binding, conserved site SPSF3K_RS00245 af5b424267c0a532ccfd100d0c2e8ce1 512 Pfam PF00501 AMP-binding enzyme 8 400 7.8E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SPSF3K_RS00245 af5b424267c0a532ccfd100d0c2e8ce1 512 Gene3D G3DSA:2.30.38.10 312 393 1.9E-19 T 29-03-2018 SPSF3K_RS00245 af5b424267c0a532ccfd100d0c2e8ce1 512 Gene3D G3DSA:3.30.300.30 396 511 6.3E-29 T 29-03-2018 SPSF3K_RS00245 af5b424267c0a532ccfd100d0c2e8ce1 512 Gene3D G3DSA:3.40.50.980 161 311 2.7E-39 T 29-03-2018 SPSF3K_RS08345 782981ca3a28e8ce2b00f50fb0bb84f0 494 Gene3D G3DSA:3.10.630.10 226 277 7.8E-16 T 29-03-2018 SPSF3K_RS08345 782981ca3a28e8ce2b00f50fb0bb84f0 494 Gene3D G3DSA:3.10.630.10 3 225 5.4E-106 T 29-03-2018 SPSF3K_RS08345 782981ca3a28e8ce2b00f50fb0bb84f0 494 Pfam PF08903 Domain of unknown function (DUF1846) 5 492 7.4E-239 T 29-03-2018 IPR014999 Uncharacterised protein family UPF0371 SPSF3K_RS08345 782981ca3a28e8ce2b00f50fb0bb84f0 494 Gene3D G3DSA:1.20.1570.10 278 339 3.7E-28 T 29-03-2018 SPSF3K_RS08345 782981ca3a28e8ce2b00f50fb0bb84f0 494 PIRSF PIRSF033132 2 494 4.7E-266 T 29-03-2018 IPR014999 Uncharacterised protein family UPF0371 SPSF3K_RS08345 782981ca3a28e8ce2b00f50fb0bb84f0 494 Hamap MF_01567 UPF0371 protein . 2 494 60.986 T 29-03-2018 IPR014999 Uncharacterised protein family UPF0371 SPSF3K_RS04065 b9c3e9a8ae4169a35b50614802276606 488 Pfam PF09154 Domain of unknown function (DUF1939) 425 481 4.3E-12 T 29-03-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 SPSF3K_RS04065 b9c3e9a8ae4169a35b50614802276606 488 Gene3D G3DSA:3.20.20.80 2 407 8.7E-75 T 29-03-2018 SPSF3K_RS04065 b9c3e9a8ae4169a35b50614802276606 488 PIRSF PIRSF001021 1 487 9.1E-219 T 29-03-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 SPSF3K_RS04065 b9c3e9a8ae4169a35b50614802276606 488 Pfam PF00128 Alpha amylase, catalytic domain 30 374 5.4E-31 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS04065 b9c3e9a8ae4169a35b50614802276606 488 Gene3D G3DSA:2.60.40.1180 408 487 6.0E-33 T 29-03-2018 SPSF3K_RS04065 b9c3e9a8ae4169a35b50614802276606 488 SUPERFAMILY SSF51445 5 377 3.53E-100 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS04065 b9c3e9a8ae4169a35b50614802276606 488 SMART SM00642 4 414 4.6E-59 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS04065 b9c3e9a8ae4169a35b50614802276606 488 SUPERFAMILY SSF51011 396 484 3.31E-33 T 29-03-2018 SPSF3K_RS06715 676c116e7ebcc491ea1be7327a2b74c4 418 Gene3D G3DSA:3.40.630.30 125 390 9.8E-25 T 29-03-2018 SPSF3K_RS06715 676c116e7ebcc491ea1be7327a2b74c4 418 SUPERFAMILY SSF55729 168 246 4.5E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS06715 676c116e7ebcc491ea1be7327a2b74c4 418 SUPERFAMILY SSF55729 306 394 4.5E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS06715 676c116e7ebcc491ea1be7327a2b74c4 418 Pfam PF02388 FemAB family 17 394 6.0E-53 T 29-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 SPSF3K_RS06715 676c116e7ebcc491ea1be7327a2b74c4 418 SUPERFAMILY SSF55729 1 143 2.65E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS04815 f449abb05a54fd5eb29ec061bc06bb4b 246 PIRSF PIRSF005426 1 246 4.3E-77 T 29-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 SPSF3K_RS04815 f449abb05a54fd5eb29ec061bc06bb4b 246 Gene3D G3DSA:3.40.109.10 1 246 3.7E-50 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SPSF3K_RS04815 f449abb05a54fd5eb29ec061bc06bb4b 246 Pfam PF00881 Nitroreductase family 12 165 5.0E-18 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 SPSF3K_RS04815 f449abb05a54fd5eb29ec061bc06bb4b 246 SUPERFAMILY SSF55469 1 243 4.32E-62 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 SPSF3K_RS02030 1bc5eaae33e9e0943f01898ea5578978 328 Pfam PF04392 ABC transporter substrate binding protein 43 323 1.5E-89 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein SPSF3K_RS02030 1bc5eaae33e9e0943f01898ea5578978 328 Gene3D G3DSA:3.40.50.2300 165 298 1.4E-22 T 29-03-2018 SPSF3K_RS02030 1bc5eaae33e9e0943f01898ea5578978 328 SUPERFAMILY SSF53822 49 307 1.88E-15 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS02030 1bc5eaae33e9e0943f01898ea5578978 328 Gene3D G3DSA:3.40.50.2300 40 164 2.0E-20 T 29-03-2018 SPSF3K_RS01630 cda38ee5364af04fe9086d29821c1f70 165 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 165 7.8E-48 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SPSF3K_RS01630 cda38ee5364af04fe9086d29821c1f70 165 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 36.105 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SPSF3K_RS01630 cda38ee5364af04fe9086d29821c1f70 165 SUPERFAMILY SSF50249 1 165 1.34E-56 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS01630 cda38ee5364af04fe9086d29821c1f70 165 Gene3D G3DSA:2.40.50.140 1 111 2.3E-39 T 29-03-2018 SPSF3K_RS01630 cda38ee5364af04fe9086d29821c1f70 165 Pfam PF00436 Single-strand binding protein family 2 103 1.6E-35 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SPSF3K_RS01630 cda38ee5364af04fe9086d29821c1f70 165 PIRSF PIRSF002070 1 148 1.2E-37 T 29-03-2018 SPSF3K_RS09030 f0a17275017ccb4e97fc2819c9a3cc2e 324 Pfam PF13377 Periplasmic binding protein-like domain 167 321 4.4E-20 T 29-03-2018 SPSF3K_RS09030 f0a17275017ccb4e97fc2819c9a3cc2e 324 Gene3D G3DSA:1.10.260.40 2 57 3.4E-21 T 29-03-2018 SPSF3K_RS09030 f0a17275017ccb4e97fc2819c9a3cc2e 324 Gene3D G3DSA:3.40.50.2300 163 324 5.3E-35 T 29-03-2018 SPSF3K_RS09030 f0a17275017ccb4e97fc2819c9a3cc2e 324 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 SPSF3K_RS09030 f0a17275017ccb4e97fc2819c9a3cc2e 324 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.8E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09030 f0a17275017ccb4e97fc2819c9a3cc2e 324 SMART SM00354 1 71 1.5E-32 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS09030 f0a17275017ccb4e97fc2819c9a3cc2e 324 SUPERFAMILY SSF47413 2 58 6.75E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS09030 f0a17275017ccb4e97fc2819c9a3cc2e 324 Gene3D G3DSA:3.40.50.2300 58 162 3.3E-22 T 29-03-2018 SPSF3K_RS09030 f0a17275017ccb4e97fc2819c9a3cc2e 324 SUPERFAMILY SSF53822 61 322 1.61E-52 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 Gene3D G3DSA:1.10.1040.10 283 367 1.3E-11 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 Gene3D G3DSA:1.10.1040.10 187 275 1.3E-17 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 SUPERFAMILY SSF48179 187 269 8.42E-16 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 Gene3D G3DSA:3.90.226.10 368 681 9.4E-63 T 29-03-2018 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 SUPERFAMILY SSF51735 6 186 3.07E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 290 352 1.1E-6 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 271 1.9E-17 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 Pfam PF16113 Enoyl-CoA hydratase/isomerase 383 672 3.0E-41 T 29-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 472 492 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 Gene3D G3DSA:3.40.50.720 2 186 1.3E-49 T 29-03-2018 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 184 1.4E-54 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 SUPERFAMILY SSF52096 368 561 6.8E-62 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 SUPERFAMILY SSF52096 612 679 6.8E-62 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SPSF3K_RS00240 2d998ed670a89657d7b0a1d73819f34b 682 SUPERFAMILY SSF48179 288 363 1.45E-10 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPSF3K_RS06685 1ba451d8a78ec3792313654c083fc2d7 140 SUPERFAMILY SSF51182 4 121 8.69E-27 T 29-03-2018 IPR011051 RmlC-like cupin domain SPSF3K_RS06685 1ba451d8a78ec3792313654c083fc2d7 140 Pfam PF07883 Cupin domain 41 116 2.8E-15 T 29-03-2018 IPR013096 Cupin 2, conserved barrel SPSF3K_RS06685 1ba451d8a78ec3792313654c083fc2d7 140 Gene3D G3DSA:2.60.120.10 16 140 8.2E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold SPSF3K_RS10890 56ead2fe499e7e0f507f17e6ea745e50 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 188 2.0E-66 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPSF3K_RS10890 56ead2fe499e7e0f507f17e6ea745e50 189 Gene3D G3DSA:3.40.50.1470 1 189 1.6E-69 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPSF3K_RS10890 56ead2fe499e7e0f507f17e6ea745e50 189 Pfam PF01195 Peptidyl-tRNA hydrolase 4 188 1.3E-58 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPSF3K_RS10890 56ead2fe499e7e0f507f17e6ea745e50 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 180 37.664 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPSF3K_RS10890 56ead2fe499e7e0f507f17e6ea745e50 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 15 28 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SPSF3K_RS10890 56ead2fe499e7e0f507f17e6ea745e50 189 SUPERFAMILY SSF53178 1 188 4.84E-68 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPSF3K_RS10890 56ead2fe499e7e0f507f17e6ea745e50 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SPSF3K_RS08795 8747a3ffe49ac5b1a87534e21ce059fd 279 Gene3D G3DSA:3.40.50.10170 1 154 3.3E-47 T 29-03-2018 SPSF3K_RS08795 8747a3ffe49ac5b1a87534e21ce059fd 279 SUPERFAMILY SSF82549 1 278 2.49E-81 T 29-03-2018 SPSF3K_RS08795 8747a3ffe49ac5b1a87534e21ce059fd 279 Gene3D G3DSA:3.30.1180.10 155 279 1.6E-25 T 29-03-2018 SPSF3K_RS08795 8747a3ffe49ac5b1a87534e21ce059fd 279 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 278 1.2E-87 T 29-03-2018 IPR003797 DegV SPSF3K_RS08795 8747a3ffe49ac5b1a87534e21ce059fd 279 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 276 5.4E-87 T 29-03-2018 IPR003797 DegV SPSF3K_RS08325 11d10e2cd9248c325af6d808699b4434 305 Pfam PF01544 CorA-like Mg2+ transporter protein 34 303 8.2E-45 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SPSF3K_RS08325 11d10e2cd9248c325af6d808699b4434 305 SUPERFAMILY SSF144083 240 303 1.7E-17 T 29-03-2018 SPSF3K_RS08325 11d10e2cd9248c325af6d808699b4434 305 SUPERFAMILY SSF143865 55 236 3.66E-20 T 29-03-2018 SPSF3K_RS08325 11d10e2cd9248c325af6d808699b4434 305 Gene3D G3DSA:1.20.58.340 121 237 1.8E-11 T 29-03-2018 SPSF3K_RS08325 11d10e2cd9248c325af6d808699b4434 305 Gene3D G3DSA:1.20.58.340 238 305 1.5E-19 T 29-03-2018 SPSF3K_RS07055 f98c5ecb5f7d488ebaa29b03d2082baa 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 215 6.5E-77 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SPSF3K_RS07055 f98c5ecb5f7d488ebaa29b03d2082baa 217 SUPERFAMILY SSF109755 3 216 3.14E-64 T 29-03-2018 SPSF3K_RS07055 f98c5ecb5f7d488ebaa29b03d2082baa 217 Gene3D G3DSA:1.20.58.220 1 112 4.1E-29 T 29-03-2018 SPSF3K_RS07055 f98c5ecb5f7d488ebaa29b03d2082baa 217 Gene3D G3DSA:1.20.58.220 113 217 8.8E-25 T 29-03-2018 SPSF3K_RS07055 f98c5ecb5f7d488ebaa29b03d2082baa 217 PIRSF PIRSF003107 1 217 4.9E-66 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SPSF3K_RS07055 f98c5ecb5f7d488ebaa29b03d2082baa 217 Pfam PF01895 PhoU domain 121 206 1.1E-17 T 29-03-2018 IPR026022 PhoU domain SPSF3K_RS07055 f98c5ecb5f7d488ebaa29b03d2082baa 217 Pfam PF01895 PhoU domain 18 104 6.2E-24 T 29-03-2018 IPR026022 PhoU domain SPSF3K_RS00910 e93d58229ad349502d10fce0d58e32b0 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 396 4.1E-59 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS00910 e93d58229ad349502d10fce0d58e32b0 455 Pfam PF01554 MatE 19 179 7.0E-31 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS00910 e93d58229ad349502d10fce0d58e32b0 455 Pfam PF01554 MatE 241 401 8.9E-18 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS00910 e93d58229ad349502d10fce0d58e32b0 455 PIRSF PIRSF006603 1 449 3.3E-92 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS08050 260af7a3b9e8c5a61b3a4a9fe5ed2c08 551 Gene3D G3DSA:2.30.310.10 1 167 5.4E-50 T 29-03-2018 SPSF3K_RS08050 260af7a3b9e8c5a61b3a4a9fe5ed2c08 551 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 427 4.3E-142 T 29-03-2018 SPSF3K_RS08050 260af7a3b9e8c5a61b3a4a9fe5ed2c08 551 Pfam PF05670 Domain of unknown function (DUF814) 434 519 1.4E-23 T 29-03-2018 IPR008532 Domain of unknown function DUF814 SPSF3K_RS08050 260af7a3b9e8c5a61b3a4a9fe5ed2c08 551 Gene3D G3DSA:3.40.970.40 233 274 5.0E-7 T 29-03-2018 SPSF3K_RS07235 2286d8455a8b18a17579c21a135dc1d6 145 Gene3D G3DSA:3.40.930.10 2 144 1.9E-29 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS07235 2286d8455a8b18a17579c21a135dc1d6 145 SUPERFAMILY SSF55804 3 143 4.32E-35 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS07235 2286d8455a8b18a17579c21a135dc1d6 145 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3 143 2.5E-31 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS07235 2286d8455a8b18a17579c21a135dc1d6 145 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 46 62 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 PIRSF PIRSF000414 1 514 6.4E-207 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2 514 7.8E-214 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 Gene3D G3DSA:3.40.140.20 363 504 1.9E-49 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 SUPERFAMILY SSF53927 208 514 3.51E-119 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 Gene3D G3DSA:3.40.50.1380 1 191 2.0E-72 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 514 43.815 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 SMART SM00851 13 128 8.9E-51 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 448 4.1E-115 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 SUPERFAMILY SSF52335 2 193 2.44E-69 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 SMART SM00798 133 449 3.5E-184 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 Pfam PF02142 MGS-like domain 13 127 3.6E-25 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain SPSF3K_RS10605 2290f4b24cf61611ac729433f66d7195 514 Gene3D G3DSA:3.40.140.20 222 361 6.1E-51 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 SPSF3K_RS07585 31eebe68b713a2a448e124a8ec99c58c 76 Pfam PF11184 Protein of unknown function (DUF2969) 1 75 4.2E-25 T 29-03-2018 IPR021351 Protein of unknown function DUF2969 SPSF3K_RS04825 31501e55d7e8c959ce2fa5964d3bef43 198 Pfam PF06736 Protein of unknown function (DUF1211) 5 89 5.8E-26 T 29-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 SPSF3K_RS06285 f3b87d667e67acfa61dffc39dd48e1ed 330 SUPERFAMILY SSF53659 7 326 3.58E-95 T 29-03-2018 SPSF3K_RS06285 f3b87d667e67acfa61dffc39dd48e1ed 330 Pfam PF01515 Phosphate acetyl/butaryl transferase 10 323 1.1E-120 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SPSF3K_RS06285 f3b87d667e67acfa61dffc39dd48e1ed 330 Gene3D G3DSA:3.40.718.10 21 301 4.5E-65 T 29-03-2018 SPSF3K_RS06285 f3b87d667e67acfa61dffc39dd48e1ed 330 PIRSF PIRSF000428 1 330 2.3E-110 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SPSF3K_RS06285 f3b87d667e67acfa61dffc39dd48e1ed 330 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 21 323 2.0E-120 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 SPSF3K_RS09300 430337f350fe0a284c5f9116f721aef5 405 Pfam PF12698 ABC-2 family transporter protein 19 376 2.4E-43 T 29-03-2018 SPSF3K_RS09300 430337f350fe0a284c5f9116f721aef5 405 Gene3D G3DSA:3.40.190.10 45 149 2.1E-14 T 29-03-2018 SPSF3K_RS03715 f788fea6499d8ac6568aa0df354fa2e7 275 Gene3D G3DSA:3.60.10.10 1 275 2.5E-37 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SPSF3K_RS03715 f788fea6499d8ac6568aa0df354fa2e7 275 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 273 2.0E-54 T 29-03-2018 SPSF3K_RS03715 f788fea6499d8ac6568aa0df354fa2e7 275 SUPERFAMILY SSF56219 1 275 1.57E-57 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SPSF3K_RS03715 f788fea6499d8ac6568aa0df354fa2e7 275 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 234 245 - T 29-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 SPSF3K_RS03715 f788fea6499d8ac6568aa0df354fa2e7 275 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 207 223 - T 29-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 SPSF3K_RS03715 f788fea6499d8ac6568aa0df354fa2e7 275 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 274 3.8E-80 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SPSF3K_RS03715 f788fea6499d8ac6568aa0df354fa2e7 275 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 251 2.6E-17 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase SPSF3K_RS03715 f788fea6499d8ac6568aa0df354fa2e7 275 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 37 46 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 Gene3D G3DSA:3.30.360.10 120 224 4.5E-37 T 29-03-2018 SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 3 255 5.3E-73 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 Gene3D G3DSA:3.40.50.720 1 112 1.1E-24 T 29-03-2018 SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 3 255 28.256 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 140 157 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 PIRSF PIRSF000161 1 255 7.5E-70 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 SUPERFAMILY SSF51735 3 145 9.14E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 121 255 1.7E-35 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 118 2.0E-27 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS05355 9bc41e7abd5e597e13d521d59d204f1e 255 SUPERFAMILY SSF55347 119 227 7.63E-38 T 29-03-2018 SPSF3K_RS10875 1ed1ef1ab7983493fcb5dda115563485 90 SUPERFAMILY SSF55174 1 77 2.88E-20 T 29-03-2018 SPSF3K_RS10875 1ed1ef1ab7983493fcb5dda115563485 90 Gene3D G3DSA:3.10.290.10 1 90 1.7E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS10875 1ed1ef1ab7983493fcb5dda115563485 90 Pfam PF01479 S4 domain 1 47 4.0E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS10875 1ed1ef1ab7983493fcb5dda115563485 90 SMART SM00363 1 62 1.5E-6 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 SPSF3K_RS10875 1ed1ef1ab7983493fcb5dda115563485 90 PIRSF PIRSF038881 1 89 2.2E-39 T 29-03-2018 IPR025490 RNA-binding protein, HP1423 type SPSF3K_RS00510 878095c6fcbab8d716f16a7398bc747b 729 Gene3D G3DSA:3.20.70.20 134 700 2.4E-204 T 29-03-2018 SPSF3K_RS00510 878095c6fcbab8d716f16a7398bc747b 729 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 128 718 4.7E-183 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 SPSF3K_RS00510 878095c6fcbab8d716f16a7398bc747b 729 ProSitePatterns PS00850 Glycine radical domain signature. 689 697 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site SPSF3K_RS00510 878095c6fcbab8d716f16a7398bc747b 729 Pfam PF03477 ATP cone domain 12 103 1.8E-20 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 SPSF3K_RS00510 878095c6fcbab8d716f16a7398bc747b 729 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 129 718 1.2E-182 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 SPSF3K_RS00510 878095c6fcbab8d716f16a7398bc747b 729 SUPERFAMILY SSF51998 134 700 5.04E-196 T 29-03-2018 SPSF3K_RS05125 09a4203736a4a0fa4f17bce4aab7fdb2 736 Pfam PF00884 Sulfatase 254 558 3.3E-35 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SPSF3K_RS05125 09a4203736a4a0fa4f17bce4aab7fdb2 736 SUPERFAMILY SSF53649 252 662 2.43E-70 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SPSF3K_RS05125 09a4203736a4a0fa4f17bce4aab7fdb2 736 Gene3D G3DSA:3.40.720.10 247 568 4.0E-34 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SPSF3K_RS05125 09a4203736a4a0fa4f17bce4aab7fdb2 736 PIRSF PIRSF005091 1 648 5.8E-175 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like SPSF3K_RS09045 f7b89aa5ab25cf0a96ffeb0b2a6ea91b 179 PIRSF PIRSF004553 1 179 4.6E-57 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 SPSF3K_RS09045 f7b89aa5ab25cf0a96ffeb0b2a6ea91b 179 Gene3D G3DSA:3.40.50.150 1 179 4.6E-34 T 29-03-2018 SPSF3K_RS09045 f7b89aa5ab25cf0a96ffeb0b2a6ea91b 179 Pfam PF03602 Conserved hypothetical protein 95 1 177 2.3E-64 T 29-03-2018 SPSF3K_RS09045 f7b89aa5ab25cf0a96ffeb0b2a6ea91b 179 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 114 120 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SPSF3K_RS09045 f7b89aa5ab25cf0a96ffeb0b2a6ea91b 179 SUPERFAMILY SSF53335 1 178 7.31E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS09045 f7b89aa5ab25cf0a96ffeb0b2a6ea91b 179 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 177 1.5E-52 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 Gene3D G3DSA:1.10.10.60 133 184 1.5E-9 T 29-03-2018 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 Pfam PF02796 Helix-turn-helix domain of resolvase 140 183 1.1E-13 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 Gene3D G3DSA:3.40.50.1390 1 106 7.9E-34 T 29-03-2018 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 SUPERFAMILY SSF46689 140 181 2.15E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 Pfam PF00239 Resolvase, N terminal domain 3 137 2.4E-44 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 Gene3D G3DSA:1.20.5.40 107 132 1.1E-16 T 29-03-2018 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 SUPERFAMILY SSF53041 2 137 6.93E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS05690 4c1e736bd93f8335f9c9123c6a0b4496 184 SMART SM00857 2 138 1.6E-58 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS09245 60ba5338f048c8fe864b0afb445300fd 464 SUPERFAMILY SSF102114 101 424 4.97E-33 T 29-03-2018 SPSF3K_RS09245 60ba5338f048c8fe864b0afb445300fd 464 Pfam PF04055 Radical SAM superfamily 104 264 1.1E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 SPSF3K_RS09245 60ba5338f048c8fe864b0afb445300fd 464 Gene3D G3DSA:3.20.20.70 93 445 2.9E-19 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS09245 60ba5338f048c8fe864b0afb445300fd 464 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 364 429 8.8E-8 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain SPSF3K_RS09245 60ba5338f048c8fe864b0afb445300fd 464 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 104 115 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 SPSF3K_RS09245 60ba5338f048c8fe864b0afb445300fd 464 Pfam PF13353 4Fe-4S single cluster domain 105 215 1.2E-10 T 29-03-2018 SPSF3K_RS08740 0a0476ddc9bd2a04a1a774e11c9273ef 696 Pfam PF00905 Penicillin binding protein transpeptidase domain 354 686 2.5E-70 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SPSF3K_RS08740 0a0476ddc9bd2a04a1a774e11c9273ef 696 Gene3D G3DSA:3.90.1310.10 35 321 1.5E-26 T 29-03-2018 SPSF3K_RS08740 0a0476ddc9bd2a04a1a774e11c9273ef 696 Gene3D G3DSA:3.40.710.10 322 696 2.0E-66 T 29-03-2018 SPSF3K_RS08740 0a0476ddc9bd2a04a1a774e11c9273ef 696 SUPERFAMILY SSF56519 61 124 4.45E-28 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SPSF3K_RS08740 0a0476ddc9bd2a04a1a774e11c9273ef 696 SUPERFAMILY SSF56519 191 321 4.45E-28 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SPSF3K_RS08740 0a0476ddc9bd2a04a1a774e11c9273ef 696 SUPERFAMILY SSF56601 322 694 1.38E-61 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS08740 0a0476ddc9bd2a04a1a774e11c9273ef 696 Pfam PF03717 Penicillin-binding Protein dimerisation domain 68 306 1.0E-31 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SPSF3K_RS02410 2212e949b2d1f57dd31318a620fa0889 139 SUPERFAMILY SSF55729 1 137 7.2E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS02410 2212e949b2d1f57dd31318a620fa0889 139 Gene3D G3DSA:3.40.630.30 1 81 4.2E-11 T 29-03-2018 SPSF3K_RS02410 2212e949b2d1f57dd31318a620fa0889 139 Pfam PF00583 Acetyltransferase (GNAT) family 28 132 9.8E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS02410 2212e949b2d1f57dd31318a620fa0889 139 Gene3D G3DSA:3.40.630.30 82 139 4.0E-10 T 29-03-2018 SPSF3K_RS06350 69b961e41ed70ba926fd2e776cf5e343 311 Pfam PF02424 ApbE family 10 287 3.2E-66 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SPSF3K_RS06350 69b961e41ed70ba926fd2e776cf5e343 311 Gene3D G3DSA:3.10.520.10 3 307 5.9E-44 T 29-03-2018 SPSF3K_RS06350 69b961e41ed70ba926fd2e776cf5e343 311 SUPERFAMILY SSF143631 7 307 3.14E-79 T 29-03-2018 IPR003374 ApbE-like domain SPSF3K_RS06350 69b961e41ed70ba926fd2e776cf5e343 311 PIRSF PIRSF006268 2 311 2.5E-81 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 SPSF3K_RS04275 aa72f85711e3b290d62da53f234ea159 176 Pfam PF12732 YtxH-like protein 5 77 6.5E-12 T 29-03-2018 IPR024623 Uncharacterised protein family YtxH SPSF3K_RS04275 aa72f85711e3b290d62da53f234ea159 176 Gene3D G3DSA:3.40.50.300 15 121 1.8E-4 T 29-03-2018 SPSF3K_RS02135 b2f19dfcbcea57969642111258772164 294 SUPERFAMILY SSF160964 13 45 1.44E-6 T 29-03-2018 SPSF3K_RS02135 b2f19dfcbcea57969642111258772164 294 Gene3D G3DSA:1.10.3720.10 63 293 5.9E-44 T 29-03-2018 SPSF3K_RS02135 b2f19dfcbcea57969642111258772164 294 Gene3D G3DSA:1.20.58.370 2 45 1.5E-7 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SPSF3K_RS02135 b2f19dfcbcea57969642111258772164 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 286 1.0E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS02135 b2f19dfcbcea57969642111258772164 294 SUPERFAMILY SSF161098 56 281 9.55E-61 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 Gene3D G3DSA:1.20.120.330 22 191 3.2E-6 T 29-03-2018 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 SUPERFAMILY SSF53955 1262 1357 2.5E-12 T 29-03-2018 IPR023346 Lysozyme-like domain SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 Gene3D G3DSA:1.20.120.570 194 268 0.0099 T 29-03-2018 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 Pfam PF01464 Transglycosylase SLT domain 1285 1357 1.4E-8 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 SUPERFAMILY SSF54001 1082 1192 1.86E-9 T 29-03-2018 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 40 578 0.002 T 29-03-2018 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 Pfam PF05257 CHAP domain 1102 1180 7.3E-8 T 29-03-2018 IPR007921 CHAP domain SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 Gene3D G3DSA:1.10.287.700 971 1101 5.2E-4 T 29-03-2018 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 Gene3D G3DSA:1.10.287.700 777 873 4.1E-8 T 29-03-2018 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 363 438 2.3E-8 T 29-03-2018 IPR013491 Caudovirus, tape measure, N-terminal SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 Gene3D G3DSA:1.20.5.1230 358 541 0.004 T 29-03-2018 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 Gene3D G3DSA:1.20.5.1230 542 776 2.2E-6 T 29-03-2018 SPSF3K_RS07345 c1fb871ceb422689f5d927374976636f 1496 Gene3D G3DSA:1.10.530.10 1238 1403 2.1E-15 T 29-03-2018 SPSF3K_RS06125 237fedbb24984a0192d8269a6e5cc4b0 264 Gene3D G3DSA:1.10.3720.10 6 260 4.2E-37 T 29-03-2018 SPSF3K_RS06125 237fedbb24984a0192d8269a6e5cc4b0 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 57 258 9.7E-7 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS06125 237fedbb24984a0192d8269a6e5cc4b0 264 SUPERFAMILY SSF161098 6 258 3.74E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS07745 3ddc876b33b8dd3cc61ab21146268bf8 487 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 251 395 7.5E-26 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SPSF3K_RS07745 3ddc876b33b8dd3cc61ab21146268bf8 487 Gene3D G3DSA:3.40.190.10 96 220 6.7E-10 T 29-03-2018 SPSF3K_RS07745 3ddc876b33b8dd3cc61ab21146268bf8 487 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 251 395 2.4E-40 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SPSF3K_RS07745 3ddc876b33b8dd3cc61ab21146268bf8 487 Pfam PF02916 DNA polymerase processivity factor 76 189 1.5E-30 T 29-03-2018 IPR004190 DNA polymerase processivity factor GO:0006260 SPSF3K_RS00880 eb3fffcf8697892a817d04bb9d30db98 329 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 236 328 2.1E-44 T 29-03-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 SPSF3K_RS00880 eb3fffcf8697892a817d04bb9d30db98 329 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 5 181 1.5E-75 T 29-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 SPSF3K_RS00880 eb3fffcf8697892a817d04bb9d30db98 329 TIGRFAM TIGR00825 EIIBC-GUT: PTS system, glucitol/sorbitol-specific, IIBC component 5 329 1.1E-148 T 29-03-2018 IPR004702 Phosphotransferease, sorbitol phosphotransferase enzyme II GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 SPSF3K_RS03955 a0e0f9f8e660676dda3e15444a6876ce 196 Gene3D G3DSA:3.40.50.300 2 196 5.2E-43 T 29-03-2018 SPSF3K_RS03955 a0e0f9f8e660676dda3e15444a6876ce 196 Pfam PF01121 Dephospho-CoA kinase 4 183 8.4E-51 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SPSF3K_RS03955 a0e0f9f8e660676dda3e15444a6876ce 196 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 194 25.012 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SPSF3K_RS03955 a0e0f9f8e660676dda3e15444a6876ce 196 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 188 2.8E-52 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 SPSF3K_RS03955 a0e0f9f8e660676dda3e15444a6876ce 196 SUPERFAMILY SSF52540 1 194 1.68E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 Gene3D G3DSA:3.40.50.2300 46 171 1.0E-26 T 29-03-2018 SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 SUPERFAMILY SSF47413 3 57 8.44E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 29-03-2018 SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 5.6E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 5.6E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 3.5E-21 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 SUPERFAMILY SSF53822 62 315 1.58E-63 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 Pfam PF13377 Periplasmic binding protein-like domain 166 320 7.6E-24 T 29-03-2018 SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 Gene3D G3DSA:1.10.260.40 1 45 7.0E-20 T 29-03-2018 SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 SMART SM00354 2 72 4.3E-38 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS01680 1cdf76b792b93c6d25ba1fe3057411aa 321 Gene3D G3DSA:3.40.50.2300 172 302 9.6E-28 T 29-03-2018 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 SUPERFAMILY SSF51998 166 700 3.97E-169 T 29-03-2018 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 Pfam PF08343 Ribonucleotide reductase N-terminal 5 88 5.7E-22 T 29-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 555 577 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 PRINTS PR01183 Ribonucleotide reductase large chain signature 566 593 5.1E-26 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 PRINTS PR01183 Ribonucleotide reductase large chain signature 484 507 5.1E-26 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 PRINTS PR01183 Ribonucleotide reductase large chain signature 242 261 5.1E-26 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 PRINTS PR01183 Ribonucleotide reductase large chain signature 373 384 5.1E-26 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 PRINTS PR01183 Ribonucleotide reductase large chain signature 456 478 5.1E-26 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 93 700 7.5E-151 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 90 162 7.0E-11 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 4 718 0.0 T 29-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 Pfam PF02867 Ribonucleotide reductase, barrel domain 167 697 8.0E-137 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 Gene3D G3DSA:3.20.70.20 70 705 8.8E-150 T 29-03-2018 SPSF3K_RS09410 e2e400b19a6366145e89d4f1330d23f1 718 SUPERFAMILY SSF48168 9 165 8.24E-41 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS00425 c6066e669fa08a267501ecaefe59168e 90 Gene3D G3DSA:1.10.10.10 38 89 1.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00425 c6066e669fa08a267501ecaefe59168e 90 SUPERFAMILY SSF46955 37 86 4.94E-7 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS04195 037adf02fb9f89156353f73f5681a88c 271 Pfam PF09323 Domain of unknown function (DUF1980) 1 178 1.8E-58 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 SPSF3K_RS04195 037adf02fb9f89156353f73f5681a88c 271 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 266 7.8E-52 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 SPSF3K_RS07505 fd15621ccbe3064dd5edbd05c9395aab 101 SMART SM00530 3 58 7.0E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS07505 fd15621ccbe3064dd5edbd05c9395aab 101 Pfam PF01381 Helix-turn-helix 4 54 1.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS07505 fd15621ccbe3064dd5edbd05c9395aab 101 Gene3D G3DSA:1.10.10.10 26 73 7.6E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07505 fd15621ccbe3064dd5edbd05c9395aab 101 SUPERFAMILY SSF47413 2 66 5.38E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS07505 fd15621ccbe3064dd5edbd05c9395aab 101 Gene3D G3DSA:1.10.10.60 1 25 5.1E-15 T 29-03-2018 SPSF3K_RS05900 0e305dc84aaa42119665b734edbd506b 71 Gene3D G3DSA:1.10.1220.10 29 65 6.1E-18 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SPSF3K_RS05900 0e305dc84aaa42119665b734edbd506b 71 SUPERFAMILY SSF47598 24 71 2.59E-25 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SPSF3K_RS05900 0e305dc84aaa42119665b734edbd506b 71 Pfam PF07764 Omega Transcriptional Repressor 2 71 1.6E-47 T 29-03-2018 IPR011686 Omega transcriptional repressor SPSF3K_RS03865 da7d310032a9136d478fe875f66d0141 71 SUPERFAMILY SSF140652 2 71 8.76E-27 T 29-03-2018 IPR023089 YozE SAM-like domain SPSF3K_RS03865 da7d310032a9136d478fe875f66d0141 71 Pfam PF06855 YozE SAM-like fold 4 69 2.6E-23 T 29-03-2018 IPR023089 YozE SAM-like domain SPSF3K_RS03865 da7d310032a9136d478fe875f66d0141 71 Hamap MF_01538 UPF0346 protein . 1 71 22.136 T 29-03-2018 IPR010673 Protein of unknown function UPF0346 SPSF3K_RS03865 da7d310032a9136d478fe875f66d0141 71 PIRSF PIRSF037262 1 71 2.2E-29 T 29-03-2018 IPR010673 Protein of unknown function UPF0346 SPSF3K_RS03865 da7d310032a9136d478fe875f66d0141 71 Gene3D G3DSA:1.10.150.260 3 71 2.9E-25 T 29-03-2018 IPR023089 YozE SAM-like domain SPSF3K_RS00250 6a768103cba3174a5307c52f54ef126c 524 SMART SM00882 4 241 2.3E-52 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SPSF3K_RS00250 6a768103cba3174a5307c52f54ef126c 524 SUPERFAMILY SSF100950 275 514 5.03E-70 T 29-03-2018 SPSF3K_RS00250 6a768103cba3174a5307c52f54ef126c 524 Pfam PF01144 Coenzyme A transferase 8 240 7.2E-33 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 SPSF3K_RS00250 6a768103cba3174a5307c52f54ef126c 524 PIRSF PIRSF000858 1 520 8.5E-195 T 29-03-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 SPSF3K_RS00250 6a768103cba3174a5307c52f54ef126c 524 SUPERFAMILY SSF100950 2 256 3.14E-73 T 29-03-2018 SPSF3K_RS00250 6a768103cba3174a5307c52f54ef126c 524 Gene3D G3DSA:3.40.1080.10 1 265 1.5E-65 T 29-03-2018 SPSF3K_RS00250 6a768103cba3174a5307c52f54ef126c 524 Gene3D G3DSA:3.40.1080.10 274 521 1.1E-52 T 29-03-2018 SPSF3K_RS10385 7c4b15b62529b940d79295d9dc721cc0 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 128 2.1E-48 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10385 7c4b15b62529b940d79295d9dc721cc0 128 SUPERFAMILY SSF64263 2 128 1.07E-43 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10385 7c4b15b62529b940d79295d9dc721cc0 128 Gene3D G3DSA:3.90.1030.10 1 128 1.0E-47 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10385 7c4b15b62529b940d79295d9dc721cc0 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10385 7c4b15b62529b940d79295d9dc721cc0 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 128 27.697 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10385 7c4b15b62529b940d79295d9dc721cc0 128 Pfam PF01196 Ribosomal protein L17 16 128 3.7E-40 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS06960 e320caf63fb8fe6f8a88b6bde4327a86 93 Gene3D G3DSA:2.40.30.100 4 90 1.2E-22 T 29-03-2018 IPR015018 Protein of unknown function DUF1905 SPSF3K_RS06960 e320caf63fb8fe6f8a88b6bde4327a86 93 Pfam PF08922 Domain of unknown function (DUF1905) 7 89 3.4E-19 T 29-03-2018 IPR015018 Protein of unknown function DUF1905 SPSF3K_RS06960 e320caf63fb8fe6f8a88b6bde4327a86 93 SUPERFAMILY SSF141694 3 91 3.14E-23 T 29-03-2018 SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 Gene3D G3DSA:1.10.10.10 1 70 9.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 SUPERFAMILY SSF64288 57 237 6.44E-49 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 2.0E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 Pfam PF07702 UTRA domain 92 231 1.8E-38 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 SMART SM00345 11 69 3.9E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 SMART SM00866 91 231 1.9E-37 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 Gene3D G3DSA:3.40.1410.10 71 238 6.1E-42 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 3.0E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 3.0E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS04580 01337984422d5de18db44f051d22957e 243 SUPERFAMILY SSF46785 3 77 3.33E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07950 ff9d62784029466a1c06c8e3509620da 244 Pfam PF01643 Acyl-ACP thioesterase 4 241 2.1E-70 T 29-03-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 SPSF3K_RS07950 ff9d62784029466a1c06c8e3509620da 244 SUPERFAMILY SSF54637 1 146 6.11E-32 T 29-03-2018 IPR029069 HotDog domain SPSF3K_RS07950 ff9d62784029466a1c06c8e3509620da 244 Gene3D G3DSA:3.10.129.10 4 136 1.6E-9 T 29-03-2018 SPSF3K_RS07950 ff9d62784029466a1c06c8e3509620da 244 Gene3D G3DSA:3.10.129.10 144 240 8.5E-15 T 29-03-2018 SPSF3K_RS07950 ff9d62784029466a1c06c8e3509620da 244 SUPERFAMILY SSF54637 154 239 3.28E-21 T 29-03-2018 IPR029069 HotDog domain SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Gene3D G3DSA:2.40.30.10 636 735 6.7E-12 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 SUPERFAMILY SSF50447 646 726 1.63E-22 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Gene3D G3DSA:3.30.56.50 5 46 5.9E-13 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Gene3D G3DSA:3.30.56.50 394 435 1.4E-10 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Gene3D G3DSA:2.40.30.10 872 970 1.9E-24 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 SUPERFAMILY SSF52540 456 644 2.7E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 384 968 1.9E-244 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 392 442 5.7E-13 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 3 51 5.7E-12 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 SUPERFAMILY SSF52156 748 878 2.09E-39 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 474 630 1.4E-34 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 969 16.736 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 PRINTS PR00449 Transforming protein P21 ras signature 571 584 8.6E-5 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 PRINTS PR00449 Transforming protein P21 ras signature 474 495 8.6E-5 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 PRINTS PR00449 Transforming protein P21 ras signature 612 634 8.6E-5 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 PRINTS PR00449 Transforming protein P21 ras signature 513 535 8.6E-5 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 SMART SM00173 493 637 0.0069 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Gene3D G3DSA:3.40.50.300 466 635 3.6E-41 T 29-03-2018 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Pfam PF11987 Translation-initiation factor 2 757 861 1.8E-37 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Pfam PF00009 Elongation factor Tu GTP binding domain 475 632 1.1E-34 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 ProSitePatterns PS01176 Initiation factor 2 signature. 922 944 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 Gene3D G3DSA:3.40.50.10050 769 850 1.2E-28 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 SPSF3K_RS09940 8ad8023968112b3322b262c2a594f829 970 SUPERFAMILY SSF50447 872 968 5.42E-26 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain SPSF3K_RS07355 c58150c852c2e203788ea92c0a3947bb 204 Pfam PF04630 Phage tail tube protein 1 200 1.2E-74 T 29-03-2018 IPR006724 Phage tail tube protein 1 SPSF3K_RS05470 4dc8d43102910a80d4e61c63da57a973 166 Pfam PF00466 Ribosomal protein L10 7 102 3.2E-26 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 SPSF3K_RS05470 4dc8d43102910a80d4e61c63da57a973 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 4 162 27.351 T 29-03-2018 IPR022973 Ribosomal protein L10 SPSF3K_RS05470 4dc8d43102910a80d4e61c63da57a973 166 SUPERFAMILY SSF160369 6 161 4.84E-50 T 29-03-2018 SPSF3K_RS05470 4dc8d43102910a80d4e61c63da57a973 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 9 43 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS05470 4dc8d43102910a80d4e61c63da57a973 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 7 145 6.0E-5 T 29-03-2018 SPSF3K_RS08225 ef3c89bba2fc5767a462a0412830f087 418 Pfam PF13416 Bacterial extracellular solute-binding protein 57 358 1.2E-43 T 29-03-2018 SPSF3K_RS08225 ef3c89bba2fc5767a462a0412830f087 418 Gene3D G3DSA:3.40.190.10 175 417 1.1E-7 T 29-03-2018 SPSF3K_RS08225 ef3c89bba2fc5767a462a0412830f087 418 SUPERFAMILY SSF53850 39 392 1.19E-55 T 29-03-2018 SPSF3K_RS08225 ef3c89bba2fc5767a462a0412830f087 418 Gene3D G3DSA:3.40.190.10 31 174 2.3E-24 T 29-03-2018 SPSF3K_RS06100 73184007a178cb5e0ebc43003b6bd053 266 SUPERFAMILY SSF51717 8 265 2.62E-92 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SPSF3K_RS06100 73184007a178cb5e0ebc43003b6bd053 266 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 48 61 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SPSF3K_RS06100 73184007a178cb5e0ebc43003b6bd053 266 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 14 29 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SPSF3K_RS06100 73184007a178cb5e0ebc43003b6bd053 266 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 264 7.9E-99 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 SPSF3K_RS06100 73184007a178cb5e0ebc43003b6bd053 266 Gene3D G3DSA:3.20.20.20 142 266 5.9E-40 T 29-03-2018 SPSF3K_RS06100 73184007a178cb5e0ebc43003b6bd053 266 Gene3D G3DSA:3.20.20.20 11 141 8.2E-58 T 29-03-2018 SPSF3K_RS06100 73184007a178cb5e0ebc43003b6bd053 266 Pfam PF00809 Pterin binding enzyme 15 250 2.0E-82 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 SPSF3K_RS02565 769a60d1699066eaace4ad1ec14b4202 419 Gene3D G3DSA:2.30.42.10 204 288 7.2E-15 T 29-03-2018 SPSF3K_RS02565 769a60d1699066eaace4ad1ec14b4202 419 Pfam PF02163 Peptidase family M50 6 405 3.3E-82 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 SPSF3K_RS02565 769a60d1699066eaace4ad1ec14b4202 419 SUPERFAMILY SSF50156 160 272 7.76E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SPSF3K_RS02565 769a60d1699066eaace4ad1ec14b4202 419 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 417 3.0E-83 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 SPSF3K_RS02565 769a60d1699066eaace4ad1ec14b4202 419 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 205 247 1.2E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 SPSF3K_RS07410 2e408c13ec7401ae6ab0e52e4be5a782 152 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 18 144 1.7E-28 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family SPSF3K_RS07410 2e408c13ec7401ae6ab0e52e4be5a782 152 Pfam PF05119 Phage terminase, small subunit 29 133 5.2E-20 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family SPSF3K_RS05630 56875c277ee1837eb15ef88eeab2fedf 228 Gene3D G3DSA:1.10.10.10 25 70 0.0021 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05630 56875c277ee1837eb15ef88eeab2fedf 228 SUPERFAMILY SSF53098 71 187 3.03E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS05630 56875c277ee1837eb15ef88eeab2fedf 228 Gene3D G3DSA:3.30.420.10 71 208 9.7E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS05630 56875c277ee1837eb15ef88eeab2fedf 228 Pfam PF13610 DDE domain 74 204 3.3E-40 T 29-03-2018 IPR032874 DDE domain SPSF3K_RS09280 7f9ae6dfb876f101eb27072f513da27d 864 SUPERFAMILY SSF52540 1 230 5.83E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09280 7f9ae6dfb876f101eb27072f513da27d 864 Pfam PF00005 ABC transporter 21 169 8.8E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS09280 7f9ae6dfb876f101eb27072f513da27d 864 SMART SM00382 30 217 2.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS09280 7f9ae6dfb876f101eb27072f513da27d 864 Gene3D G3DSA:3.40.50.300 1 253 5.4E-66 T 29-03-2018 SPSF3K_RS09280 7f9ae6dfb876f101eb27072f513da27d 864 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS09280 7f9ae6dfb876f101eb27072f513da27d 864 Pfam PF02687 FtsX-like permease family 764 857 2.6E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SPSF3K_RS07145 c425697c78c68466ba26d05d8f882044 214 SUPERFAMILY SSF46785 12 87 3.27E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07145 c425697c78c68466ba26d05d8f882044 214 Gene3D G3DSA:1.10.10.10 3 78 2.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07145 c425697c78c68466ba26d05d8f882044 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 4.6E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS07145 c425697c78c68466ba26d05d8f882044 214 SMART SM00345 17 76 4.8E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS07145 c425697c78c68466ba26d05d8f882044 214 Pfam PF02080 TrkA-C domain 146 208 3.8E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPSF3K_RS07145 c425697c78c68466ba26d05d8f882044 214 SUPERFAMILY SSF116726 135 210 2.09E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPSF3K_RS07145 c425697c78c68466ba26d05d8f882044 214 Gene3D G3DSA:3.30.70.1450 121 207 3.9E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPSF3K_RS03550 714fb20fd2c79dc05720eef5474bcfba 219 Pfam PF08820 Domain of unknown function (DUF1803) 3 93 3.6E-34 T 29-03-2018 IPR014924 Protein of unknown function DUF1803 SPSF3K_RS02815 c5689bbce1f6c6a0fd1abb9d77acbc28 134 Pfam PF01380 SIS domain 15 78 3.2E-11 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS02815 c5689bbce1f6c6a0fd1abb9d77acbc28 134 SUPERFAMILY SSF53697 14 120 4.85E-16 T 29-03-2018 SPSF3K_RS02815 c5689bbce1f6c6a0fd1abb9d77acbc28 134 Gene3D G3DSA:3.40.50.10490 2 109 8.1E-16 T 29-03-2018 SPSF3K_RS06275 9dd7438c1d27bdefc415f68a5611e5fd 278 Gene3D G3DSA:3.40.50.10330 6 127 7.8E-19 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SPSF3K_RS06275 9dd7438c1d27bdefc415f68a5611e5fd 278 Pfam PF01513 ATP-NAD kinase 46 225 5.6E-22 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SPSF3K_RS06275 9dd7438c1d27bdefc415f68a5611e5fd 278 SUPERFAMILY SSF111331 37 272 4.84E-59 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SPSF3K_RS06275 9dd7438c1d27bdefc415f68a5611e5fd 278 Hamap MF_00361 NAD kinase [nadK]. 11 274 24.355 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SPSF3K_RS06275 9dd7438c1d27bdefc415f68a5611e5fd 278 Gene3D G3DSA:2.60.200.30 128 248 4.3E-26 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 Pfam PF00203 Ribosomal protein S19 3 83 4.5E-37 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 SUPERFAMILY SSF54570 3 84 1.57E-35 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 Gene3D G3DSA:3.30.860.10 1 92 4.9E-41 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 PIRSF PIRSF002144 1 92 1.3E-32 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 1.5E-47 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.593 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.0E-23 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.0E-23 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10500 399d5228dc83649e7926f0d383f91b0f 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.0E-23 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS05240 fecf0f609b8265553a4383dd0c13a4b1 414 Gene3D G3DSA:2.40.50.100 63 374 1.5E-6 T 29-03-2018 SPSF3K_RS05240 fecf0f609b8265553a4383dd0c13a4b1 414 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 275 1.4E-14 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SPSF3K_RS00625 60c757e15a0d39e141824194a952c5c5 199 Pfam PF02230 Phospholipase/Carboxylesterase 6 198 1.1E-12 T 29-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 SPSF3K_RS00625 60c757e15a0d39e141824194a952c5c5 199 SUPERFAMILY SSF53474 5 198 8.11E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS00625 60c757e15a0d39e141824194a952c5c5 199 Gene3D G3DSA:3.40.50.1820 3 199 4.4E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS10055 0e5970d9bff4f0087ac055f5e947c0b8 235 SUPERFAMILY SSF55166 88 211 4.19E-29 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SPSF3K_RS10055 0e5970d9bff4f0087ac055f5e947c0b8 235 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 88 210 1.0E-35 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 SPSF3K_RS10055 0e5970d9bff4f0087ac055f5e947c0b8 235 Gene3D G3DSA:3.30.1380.10 77 207 3.4E-29 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 SPSF3K_RS03580 f8cd2d255f00e4324d58c09c3f283bea 545 Pfam PF01943 Polysaccharide biosynthesis protein 15 316 1.6E-31 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 SPSF3K_RS03580 f8cd2d255f00e4324d58c09c3f283bea 545 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 378 524 1.8E-23 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain SPSF3K_RS00015 44a0c16e34951d3daad7532e52546e0d 159 PIRSF PIRSF004505 1 159 5.3E-52 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS00015 44a0c16e34951d3daad7532e52546e0d 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 7.7E-51 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS00015 44a0c16e34951d3daad7532e52546e0d 159 Gene3D G3DSA:3.40.1280.10 1 159 8.1E-59 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPSF3K_RS00015 44a0c16e34951d3daad7532e52546e0d 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 29.799 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS00015 44a0c16e34951d3daad7532e52546e0d 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 7.0E-57 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS00015 44a0c16e34951d3daad7532e52546e0d 159 SUPERFAMILY SSF75217 1 157 1.57E-56 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SPSF3K_RS02890 048dce8ef14c586a12fe2e5f07186abd 155 Pfam PF07155 ECF-type riboflavin transporter, S component 3 149 1.3E-27 T 29-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 SPSF3K_RS04830 348d42f179b3229d3913785418a3936d 168 PIRSF PIRSF031501 1 168 1.4E-54 T 29-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 SPSF3K_RS04830 348d42f179b3229d3913785418a3936d 168 Pfam PF06177 QueT transporter 10 162 4.5E-33 T 29-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 SPSF3K_RS07515 9c418bb933c4d83fef0bf627a3827e12 67 SMART SM00530 13 66 1.7E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS07515 9c418bb933c4d83fef0bf627a3827e12 67 SUPERFAMILY SSF47413 13 66 2.82E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS07515 9c418bb933c4d83fef0bf627a3827e12 67 Gene3D G3DSA:1.10.260.40 2 67 8.9E-7 T 29-03-2018 SPSF3K_RS02050 98678a9bf2646b757bd6ee97c745dd5e 325 Pfam PF01207 Dihydrouridine synthase (Dus) 20 318 3.5E-86 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPSF3K_RS02050 98678a9bf2646b757bd6ee97c745dd5e 325 Gene3D G3DSA:3.20.20.70 13 255 2.2E-54 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS02050 98678a9bf2646b757bd6ee97c745dd5e 325 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 102 120 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPSF3K_RS02050 98678a9bf2646b757bd6ee97c745dd5e 325 SUPERFAMILY SSF51395 17 323 4.58E-82 T 29-03-2018 SPSF3K_RS02050 98678a9bf2646b757bd6ee97c745dd5e 325 Gene3D G3DSA:1.10.1200.80 260 324 9.6E-11 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 SPSF3K_RS02050 98678a9bf2646b757bd6ee97c745dd5e 325 PIRSF PIRSF006621 7 324 4.5E-102 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPSF3K_RS02050 98678a9bf2646b757bd6ee97c745dd5e 325 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 10 321 2.1E-103 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 SPSF3K_RS03160 1881cdbe4ca3572dc282d9e44d50c2d4 364 SUPERFAMILY SSF52374 10 119 4.38E-17 T 29-03-2018 SPSF3K_RS03160 1881cdbe4ca3572dc282d9e44d50c2d4 364 SUPERFAMILY SSF52374 186 212 4.38E-17 T 29-03-2018 SPSF3K_RS03160 1881cdbe4ca3572dc282d9e44d50c2d4 364 Gene3D G3DSA:3.40.50.620 1 221 1.0E-47 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS03160 1881cdbe4ca3572dc282d9e44d50c2d4 364 Pfam PF05636 HIGH Nucleotidyl Transferase 1 343 2.6E-107 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 SPSF3K_RS03160 1881cdbe4ca3572dc282d9e44d50c2d4 364 Hamap MF_01539 UPF0348 protein . 2 361 34.255 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 SPSF3K_RS03650 074957366ca42043abf92cde82e4590d 107 Hamap MF_01159 Initiation-control protein YabA. 2 106 23.037 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 SPSF3K_RS03650 074957366ca42043abf92cde82e4590d 107 Pfam PF06156 Initiation control protein YabA 3 101 3.8E-31 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 SPSF3K_RS03650 074957366ca42043abf92cde82e4590d 107 Gene3D G3DSA:1.20.5.490 23 59 3.6E-4 T 29-03-2018 SPSF3K_RS03650 074957366ca42043abf92cde82e4590d 107 PIRSF PIRSF021439 2 107 2.2E-38 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 SPSF3K_RS06665 f5fcdbd54f84de547c8d10daa50e832f 386 Pfam PF02378 Phosphotransferase system, EIIC 110 384 3.3E-32 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS06665 f5fcdbd54f84de547c8d10daa50e832f 386 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPSF3K_RS06665 f5fcdbd54f84de547c8d10daa50e832f 386 Gene3D G3DSA:3.30.1360.60 4 78 1.1E-24 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS06665 f5fcdbd54f84de547c8d10daa50e832f 386 SUPERFAMILY SSF55604 7 83 1.09E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPSF3K_RS06665 f5fcdbd54f84de547c8d10daa50e832f 386 Pfam PF00367 phosphotransferase system, EIIB 10 42 3.5E-13 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPSF3K_RS08080 35bda00d7f8a95064f3133e050072de1 336 Gene3D G3DSA:2.130.10.10 1 334 5.3E-34 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SPSF3K_RS08080 35bda00d7f8a95064f3133e050072de1 336 SUPERFAMILY SSF51004 24 334 5.23E-33 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain SPSF3K_RS08080 35bda00d7f8a95064f3133e050072de1 336 Pfam PF10282 Lactonase, 7-bladed beta-propeller 5 333 3.4E-105 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller SPSF3K_RS05710 3ad8ed3cbaafdac027567e728e6ee009 131 Pfam PF06953 Arsenical resistance operon trans-acting repressor ArsD 1 131 3.1E-41 T 29-03-2018 IPR010712 Arsenical-resistance operon trans-acting repressor ArsD GO:0003677|GO:0045892|GO:0046685 SPSF3K_RS05555 85d29da4bf888da83c52ef170ceb5ef5 610 SUPERFAMILY SSF52540 134 546 2.97E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05555 85d29da4bf888da83c52ef170ceb5ef5 610 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 145 551 6.0E-61 T 29-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 SPSF3K_RS05555 85d29da4bf888da83c52ef170ceb5ef5 610 Gene3D G3DSA:3.40.50.300 88 565 2.4E-39 T 29-03-2018 SPSF3K_RS01700 8cf8e2d230d7a4a72b8f7bd6bdd947bd 255 Gene3D G3DSA:1.10.10.10 1 115 4.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01700 8cf8e2d230d7a4a72b8f7bd6bdd947bd 255 Gene3D G3DSA:3.40.50.10490 116 231 2.7E-14 T 29-03-2018 SPSF3K_RS01700 8cf8e2d230d7a4a72b8f7bd6bdd947bd 255 Pfam PF01380 SIS domain 119 221 4.9E-6 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 SPSF3K_RS01700 8cf8e2d230d7a4a72b8f7bd6bdd947bd 255 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 74 5.5E-15 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SPSF3K_RS01700 8cf8e2d230d7a4a72b8f7bd6bdd947bd 255 SUPERFAMILY SSF46689 1 75 2.33E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS01700 8cf8e2d230d7a4a72b8f7bd6bdd947bd 255 SUPERFAMILY SSF53697 90 224 2.45E-19 T 29-03-2018 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 SUPERFAMILY SSF51064 144 191 1.83E-13 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 Gene3D G3DSA:2.30.22.10 136 192 1.3E-17 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 ProSitePatterns PS01071 grpE protein signature. 146 190 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 Pfam PF01025 GrpE 34 191 5.1E-44 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 SUPERFAMILY SSF58014 48 137 1.02E-21 T 29-03-2018 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 Gene3D G3DSA:3.90.20.20 2 135 1.4E-19 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 PRINTS PR00773 GrpE protein signature 94 109 9.1E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 PRINTS PR00773 GrpE protein signature 66 82 9.1E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 PRINTS PR00773 GrpE protein signature 171 190 9.1E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 PRINTS PR00773 GrpE protein signature 143 158 9.1E-25 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SPSF3K_RS10135 160d2b20cb0e87b1b0407a085d71333c 192 Hamap MF_01151 Protein GrpE [grpE]. 7 192 18.91 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 SPSF3K_RS05370 948559f3dced4bc0a3b4acee6ecda91d 157 Gene3D G3DSA:3.40.630.30 1 157 1.6E-25 T 29-03-2018 SPSF3K_RS05370 948559f3dced4bc0a3b4acee6ecda91d 157 Pfam PF00583 Acetyltransferase (GNAT) family 45 133 1.7E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS05370 948559f3dced4bc0a3b4acee6ecda91d 157 SUPERFAMILY SSF55729 1 138 5.24E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS09105 2512dba73f799b8eae096cc4bbc2f30e 307 Pfam PF01544 CorA-like Mg2+ transporter protein 15 298 1.3E-36 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SPSF3K_RS09105 2512dba73f799b8eae096cc4bbc2f30e 307 SUPERFAMILY SSF144083 238 298 1.16E-11 T 29-03-2018 SPSF3K_RS09105 2512dba73f799b8eae096cc4bbc2f30e 307 Gene3D G3DSA:1.20.58.340 236 300 1.8E-10 T 29-03-2018 SPSF3K_RS09105 2512dba73f799b8eae096cc4bbc2f30e 307 SUPERFAMILY SSF143865 15 237 2.88E-17 T 29-03-2018 SPSF3K_RS09105 2512dba73f799b8eae096cc4bbc2f30e 307 Gene3D G3DSA:1.20.58.340 121 235 2.7E-5 T 29-03-2018 SPSF3K_RS03280 2800442d18af2b6ec687fbca68d60929 160 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 92 105 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 SPSF3K_RS03280 2800442d18af2b6ec687fbca68d60929 160 SUPERFAMILY SSF55729 1 158 1.08E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS03280 2800442d18af2b6ec687fbca68d60929 160 Pfam PF00583 Acetyltransferase (GNAT) family 15 138 2.3E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS03280 2800442d18af2b6ec687fbca68d60929 160 Gene3D G3DSA:3.40.630.30 1 160 6.1E-20 T 29-03-2018 SPSF3K_RS06140 5620cac27fd2d6b4161a32aa16d27e30 223 Pfam PF00072 Response regulator receiver domain 3 113 1.2E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS06140 5620cac27fd2d6b4161a32aa16d27e30 223 PIRSF PIRSF006171 1 223 1.4E-72 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SPSF3K_RS06140 5620cac27fd2d6b4161a32aa16d27e30 223 SUPERFAMILY SSF46785 156 221 5.56E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06140 5620cac27fd2d6b4161a32aa16d27e30 223 Gene3D G3DSA:3.40.50.2300 1 142 9.0E-28 T 29-03-2018 SPSF3K_RS06140 5620cac27fd2d6b4161a32aa16d27e30 223 SMART SM00448 1 114 2.3E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS06140 5620cac27fd2d6b4161a32aa16d27e30 223 Gene3D G3DSA:1.10.10.10 145 222 9.7E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06140 5620cac27fd2d6b4161a32aa16d27e30 223 SUPERFAMILY SSF52172 1 134 4.41E-28 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS00340 0e2c0b4a90b07cba06822e2925fad838 117 PIRSF PIRSF021287 2 117 7.7E-26 T 29-03-2018 IPR016783 Biofilm formation YmcA SPSF3K_RS00340 0e2c0b4a90b07cba06822e2925fad838 117 SUPERFAMILY SSF158622 2 114 2.27E-16 T 29-03-2018 IPR023378 YheA/YmcA-like domain SPSF3K_RS00340 0e2c0b4a90b07cba06822e2925fad838 117 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 6 109 3.5E-7 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA SPSF3K_RS00340 0e2c0b4a90b07cba06822e2925fad838 117 Gene3D G3DSA:1.20.1500.10 4 111 1.4E-11 T 29-03-2018 IPR023378 YheA/YmcA-like domain SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 Pfam PF00455 DeoR C terminal sensor domain 68 227 1.7E-46 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 Gene3D G3DSA:3.40.50.1360 66 233 5.3E-35 T 29-03-2018 SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 ProSitePatterns PS00894 DeoR-type HTH domain signature. 3 37 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 SMART SM00420 3 55 1.8E-15 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 21 35 4.7E-6 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 35 53 4.7E-6 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 SMART SM01134 66 228 7.4E-56 T 29-03-2018 SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 Pfam PF08220 DeoR-like helix-turn-helix domain 3 57 1.7E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 Gene3D G3DSA:1.10.10.10 1 57 7.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 SUPERFAMILY SSF46785 2 56 4.66E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS02100 89a662be74546ad4038e3bc3f07bed20 247 SUPERFAMILY SSF100950 67 229 9.77E-33 T 29-03-2018 SPSF3K_RS08715 f28f0f52c2843d6b7593201754e88f91 230 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 17 212 5.4E-32 T 29-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 SPSF3K_RS08715 f28f0f52c2843d6b7593201754e88f91 230 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 11 187 2.0E-26 T 29-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 SPSF3K_RS05595 570cc25b3c68f75c0730f8414254b84d 547 Pfam PF03432 Relaxase/Mobilisation nuclease domain 19 280 5.8E-49 T 29-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 SPSF3K_RS02770 eaf6c68b0a10ce03c8200ecaa89d35cc 34 SUPERFAMILY SSF52777 3 33 4.27E-9 T 29-03-2018 SPSF3K_RS02770 eaf6c68b0a10ce03c8200ecaa89d35cc 34 Gene3D G3DSA:3.30.559.10 1 34 2.4E-8 T 29-03-2018 SPSF3K_RS02770 eaf6c68b0a10ce03c8200ecaa89d35cc 34 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 3 33 1.4E-8 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 SPSF3K_RS01865 533b8ee3e3c3d77e54e9dc3c6e3fafeb 475 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 452 1.1E-156 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SPSF3K_RS01865 533b8ee3e3c3d77e54e9dc3c6e3fafeb 475 PIRSF PIRSF006446 1 470 5.7E-144 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 SPSF3K_RS02035 270cee76137f23c47a5390b0e90ed1b6 294 Gene3D G3DSA:1.10.3470.10 1 283 2.1E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS02035 270cee76137f23c47a5390b0e90ed1b6 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 276 1.2E-28 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPSF3K_RS10040 54a2fbfa336dc79f14e82bd27cd1eae7 120 PIRSF PIRSF021265 1 120 2.0E-55 T 29-03-2018 IPR010360 Protein of unknown function DUF956 SPSF3K_RS10040 54a2fbfa336dc79f14e82bd27cd1eae7 120 Pfam PF06115 Domain of unknown function (DUF956) 1 114 1.7E-46 T 29-03-2018 IPR010360 Protein of unknown function DUF956 SPSF3K_RS07700 de42128a307927834a389f99083ca045 360 Pfam PF00534 Glycosyl transferases group 1 178 296 2.6E-21 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SPSF3K_RS07700 de42128a307927834a389f99083ca045 360 Pfam PF13439 Glycosyltransferase Family 4 7 166 1.7E-7 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SPSF3K_RS07700 de42128a307927834a389f99083ca045 360 Gene3D G3DSA:3.40.50.2000 168 328 4.4E-26 T 29-03-2018 SPSF3K_RS07700 de42128a307927834a389f99083ca045 360 SUPERFAMILY SSF53756 7 356 4.49E-46 T 29-03-2018 SPSF3K_RS00400 8657e8ef21eca98df2629769a3226c42 191 Gene3D G3DSA:1.20.58.60 15 166 2.0E-4 T 29-03-2018 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 Gene3D G3DSA:1.25.40.10 186 242 3.8E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 182 256 1.9E-8 T 29-03-2018 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 Gene3D G3DSA:1.25.40.10 323 406 2.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 Gene3D G3DSA:1.25.40.10 4 143 1.5E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 Gene3D G3DSA:1.25.40.10 243 322 1.5E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 SMART SM00028 97 130 190.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 SMART SM00028 234 267 470.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 SMART SM00028 167 200 0.0015 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 SMART SM00028 201 233 34.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 Gene3D G3DSA:1.25.40.10 144 185 6.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 SUPERFAMILY SSF48452 132 406 1.39E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS08065 2fe2243a7fddf27289571edca5c65ada 410 SUPERFAMILY SSF48452 11 197 3.51E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS08580 26eb542ce775cd8fc9c6e5ec278f7e2d 235 Pfam PF01596 O-methyltransferase 37 226 3.1E-28 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 SPSF3K_RS08580 26eb542ce775cd8fc9c6e5ec278f7e2d 235 SUPERFAMILY SSF53335 2 224 2.01E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS08580 26eb542ce775cd8fc9c6e5ec278f7e2d 235 Gene3D G3DSA:3.40.50.150 19 228 3.3E-38 T 29-03-2018 SPSF3K_RS09185 00c15559ebf23b0136d4eddd1a151d68 203 PIRSF PIRSF022704 1 199 4.0E-65 T 29-03-2018 IPR015987 Uncharacterised conserved protein UCP022704 SPSF3K_RS09185 00c15559ebf23b0136d4eddd1a151d68 203 Gene3D G3DSA:2.60.120.200 4 191 3.8E-38 T 29-03-2018 SPSF3K_RS09185 00c15559ebf23b0136d4eddd1a151d68 203 Pfam PF07081 Protein of unknown function (DUF1349) 11 189 7.4E-69 T 29-03-2018 IPR009784 Protein of unknown function DUF1349 SPSF3K_RS09185 00c15559ebf23b0136d4eddd1a151d68 203 SUPERFAMILY SSF49899 9 189 2.77E-40 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 SUPERFAMILY SSF55979 253 377 4.34E-28 T 29-03-2018 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 3 377 5.3E-87 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 SUPERFAMILY SSF55979 132 251 1.71E-23 T 29-03-2018 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 PIRSF PIRSF000804 2 378 1.1E-96 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 Gene3D G3DSA:3.10.150.10 131 255 4.7E-29 T 29-03-2018 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 375 4.7E-26 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 SMART SM00480 18 373 2.0E-144 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 251 7.0E-29 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 Gene3D G3DSA:3.10.150.10 258 378 8.0E-23 T 29-03-2018 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 Gene3D G3DSA:3.10.150.10 1 130 1.3E-22 T 29-03-2018 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 SUPERFAMILY SSF55979 3 127 7.53E-19 T 29-03-2018 SPSF3K_RS10910 9fc5ab709d26cbf42551611aecd17006 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 3 126 2.0E-25 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPSF3K_RS07005 9d9d59fa42ddcf0d20c6b00f0081dabe 351 SUPERFAMILY SSF53822 52 308 4.12E-17 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS07005 9d9d59fa42ddcf0d20c6b00f0081dabe 351 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 41 350 4.1E-70 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 SPSF3K_RS07005 9d9d59fa42ddcf0d20c6b00f0081dabe 351 Gene3D G3DSA:3.40.50.2300 158 350 7.7E-44 T 29-03-2018 SPSF3K_RS07005 9d9d59fa42ddcf0d20c6b00f0081dabe 351 Gene3D G3DSA:3.40.50.2300 36 157 4.1E-39 T 29-03-2018 SPSF3K_RS03455 1a7d77bafbb0674d9efedb0b84dd1f4f 525 SUPERFAMILY SSF52540 191 385 2.72E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03455 1a7d77bafbb0674d9efedb0b84dd1f4f 525 Pfam PF08706 D5 N terminal like 114 204 3.0E-5 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal SPSF3K_RS03455 1a7d77bafbb0674d9efedb0b84dd1f4f 525 SMART SM00885 77 202 3.2E-9 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal SPSF3K_RS03455 1a7d77bafbb0674d9efedb0b84dd1f4f 525 Gene3D G3DSA:3.40.50.300 173 391 5.0E-23 T 29-03-2018 SPSF3K_RS03455 1a7d77bafbb0674d9efedb0b84dd1f4f 525 Pfam PF03288 Poxvirus D5 protein-like 409 498 6.2E-11 T 29-03-2018 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal SPSF3K_RS03455 1a7d77bafbb0674d9efedb0b84dd1f4f 525 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 153 448 2.2E-85 T 29-03-2018 IPR006500 DNA primase, phage/plasmid SPSF3K_RS08655 a452877647e99953edc2dc80f2505af4 372 Pfam PF13354 Beta-lactamase enzyme family 114 306 1.1E-15 T 29-03-2018 SPSF3K_RS08655 a452877647e99953edc2dc80f2505af4 372 SUPERFAMILY SSF56601 89 323 3.59E-36 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS08655 a452877647e99953edc2dc80f2505af4 372 Gene3D G3DSA:3.40.710.10 88 323 6.4E-13 T 29-03-2018 SPSF3K_RS00530 6ea82db458b45900a95238a5f71e0eed 243 Pfam PF03883 Peroxide stress protein YaaA 2 226 6.3E-47 T 29-03-2018 IPR005583 Peroxide stress protein YaaA SPSF3K_RS00530 6ea82db458b45900a95238a5f71e0eed 243 Gene3D G3DSA:3.40.50.1010 151 236 0.076 T 29-03-2018 IPR029060 PIN domain-like SPSF3K_RS00530 6ea82db458b45900a95238a5f71e0eed 243 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 2 241 26.291 T 29-03-2018 IPR005583 Peroxide stress protein YaaA SPSF3K_RS07620 df874bb7bc70856db47798214cb9eabf 215 SUPERFAMILY SSF161098 13 199 1.09E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS07620 df874bb7bc70856db47798214cb9eabf 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 213 2.4E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS07620 df874bb7bc70856db47798214cb9eabf 215 Gene3D G3DSA:1.10.3720.10 3 203 3.4E-38 T 29-03-2018 SPSF3K_RS07620 df874bb7bc70856db47798214cb9eabf 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 108 8.0E-30 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPSF3K_RS04665 3e7859e58310749d6e37e75990064481 95 Pfam PF01817 Chorismate mutase type II 7 84 2.1E-19 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SPSF3K_RS04665 3e7859e58310749d6e37e75990064481 95 SMART SM00830 7 86 1.5E-19 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SPSF3K_RS04665 3e7859e58310749d6e37e75990064481 95 Gene3D G3DSA:1.20.59.10 1 92 8.3E-23 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SPSF3K_RS04665 3e7859e58310749d6e37e75990064481 95 TIGRFAM TIGR01805 CM_mono_grmpos: chorismate mutase 3 83 7.4E-25 T 29-03-2018 IPR011279 Chorismate mutase, Gram-positive SPSF3K_RS04665 3e7859e58310749d6e37e75990064481 95 SUPERFAMILY SSF48600 2 86 1.5E-20 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 SPSF3K_RS02005 15704d1cad1a2e143a727c5bfb676b8d 93 Pfam PF15513 Domain of unknown function (DUF4651) 33 92 3.9E-23 T 29-03-2018 IPR028105 Protein of unknown function DUF4651 SPSF3K_RS08865 510d42f6468b385dea56af5e827df46e 76 PIRSF PIRSF037356 1 76 1.2E-30 T 29-03-2018 IPR014904 Protein of unknown function DUF1797 SPSF3K_RS08865 510d42f6468b385dea56af5e827df46e 76 SUPERFAMILY SSF143567 3 76 1.96E-23 T 29-03-2018 SPSF3K_RS08865 510d42f6468b385dea56af5e827df46e 76 Pfam PF08796 Protein of unknown function (DUF1797) 8 75 1.0E-22 T 29-03-2018 IPR014904 Protein of unknown function DUF1797 SPSF3K_RS09730 914afdd6d92dae5bf9478dc64406290f 444 Pfam PF03051 Peptidase C1-like family 3 440 1.1E-201 T 29-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 SPSF3K_RS09730 914afdd6d92dae5bf9478dc64406290f 444 Gene3D G3DSA:3.90.70.10 52 443 6.7E-127 T 29-03-2018 SPSF3K_RS09730 914afdd6d92dae5bf9478dc64406290f 444 PIRSF PIRSF005700 1 444 1.3E-174 T 29-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 SPSF3K_RS09730 914afdd6d92dae5bf9478dc64406290f 444 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 361 371 - T 29-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 SPSF3K_RS09730 914afdd6d92dae5bf9478dc64406290f 444 SUPERFAMILY SSF54001 5 443 1.16E-123 T 29-03-2018 SPSF3K_RS09730 914afdd6d92dae5bf9478dc64406290f 444 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 63 74 - T 29-03-2018 IPR000169 Cysteine peptidase, cysteine active site SPSF3K_RS07430 f5a5660aee7ab38a6d371ad5d9fbbaf0 138 SUPERFAMILY SSF88659 75 132 3.55E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS07430 f5a5660aee7ab38a6d371ad5d9fbbaf0 138 TIGRFAM TIGR01636 phage_rinA: phage transcriptional regulator, RinA family 6 137 5.1E-13 T 29-03-2018 IPR006523 Transcription activator RinA SPSF3K_RS07430 f5a5660aee7ab38a6d371ad5d9fbbaf0 138 Gene3D G3DSA:1.10.10.10 77 136 3.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06310 282fef9801b5aba965ccbaa4d00d191e 317 Gene3D G3DSA:3.90.180.10 1 145 1.6E-34 T 29-03-2018 SPSF3K_RS06310 282fef9801b5aba965ccbaa4d00d191e 317 Gene3D G3DSA:3.40.50.720 146 252 8.6E-6 T 29-03-2018 SPSF3K_RS06310 282fef9801b5aba965ccbaa4d00d191e 317 SUPERFAMILY SSF50129 1 148 7.08E-28 T 29-03-2018 IPR011032 GroES-like SPSF3K_RS06310 282fef9801b5aba965ccbaa4d00d191e 317 Gene3D G3DSA:3.90.180.10 253 317 0.0048 T 29-03-2018 SPSF3K_RS06310 282fef9801b5aba965ccbaa4d00d191e 317 SMART SM00829 10 315 1.1E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SPSF3K_RS06310 282fef9801b5aba965ccbaa4d00d191e 317 Pfam PF13602 Zinc-binding dehydrogenase 188 315 4.7E-12 T 29-03-2018 SPSF3K_RS06310 282fef9801b5aba965ccbaa4d00d191e 317 SUPERFAMILY SSF51735 116 285 2.93E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS02240 c3f71d0360cf2a6b93edf03314e44b2c 345 Gene3D G3DSA:3.50.30.60 164 343 4.8E-45 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain SPSF3K_RS02240 c3f71d0360cf2a6b93edf03314e44b2c 345 Gene3D G3DSA:3.40.50.10740 2 163 2.4E-39 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain SPSF3K_RS02240 c3f71d0360cf2a6b93edf03314e44b2c 345 SUPERFAMILY SSF141986 187 335 4.71E-18 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain SPSF3K_RS02240 c3f71d0360cf2a6b93edf03314e44b2c 345 SUPERFAMILY SSF52317 4 164 4.44E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like SPSF3K_RS02240 c3f71d0360cf2a6b93edf03314e44b2c 345 PIRSF PIRSF028757 1 343 2.6E-47 T 29-03-2018 IPR003507 Peptidase family S66 SPSF3K_RS02240 c3f71d0360cf2a6b93edf03314e44b2c 345 Pfam PF02016 LD-carboxypeptidase 5 327 2.3E-58 T 29-03-2018 IPR003507 Peptidase family S66 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 17 34 2.5E-52 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 159 181 2.5E-52 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 327 348 2.5E-52 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 304 324 2.5E-52 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 366 388 2.5E-52 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 248 267 2.5E-52 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 392 411 2.5E-52 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 Pfam PF02073 Thermophilic metalloprotease (M29) 7 411 1.6E-156 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 SUPERFAMILY SSF144052 6 412 2.22E-131 T 29-03-2018 SPSF3K_RS08320 d21e6dcdbacc6f6b7a0b7f5f4a57b8a3 413 Gene3D G3DSA:3.40.1830.10 7 178 1.1E-51 T 29-03-2018 IPR035097 Peptidase M29, N-terminal SPSF3K_RS04940 c009371f2212068600f6c4c048bb832c 347 SUPERFAMILY SSF55681 97 347 2.9E-82 T 29-03-2018 SPSF3K_RS04940 c009371f2212068600f6c4c048bb832c 347 Pfam PF01409 tRNA synthetases class II core domain (F) 97 346 7.5E-107 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 SPSF3K_RS04940 c009371f2212068600f6c4c048bb832c 347 Gene3D G3DSA:3.30.930.10 10 347 3.1E-89 T 29-03-2018 SPSF3K_RS04940 c009371f2212068600f6c4c048bb832c 347 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 43 347 4.1E-106 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 SPSF3K_RS04940 c009371f2212068600f6c4c048bb832c 347 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 11 346 45.923 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 SPSF3K_RS04940 c009371f2212068600f6c4c048bb832c 347 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 26 92 9.4E-21 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SPSF3K_RS04940 c009371f2212068600f6c4c048bb832c 347 SUPERFAMILY SSF46589 24 104 8.37E-18 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 SPSF3K_RS06075 5ad1675df47a63065217984a409ef40b 295 SUPERFAMILY SSF88713 93 277 1.39E-36 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SPSF3K_RS06075 5ad1675df47a63065217984a409ef40b 295 Gene3D G3DSA:3.20.20.370 36 290 7.5E-43 T 29-03-2018 SPSF3K_RS06075 5ad1675df47a63065217984a409ef40b 295 Pfam PF01522 Polysaccharide deacetylase 130 255 3.2E-29 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 SPSF3K_RS05155 7c5c6a7a3fe8327e69ff6b49b1d2633e 415 Gene3D G3DSA:3.40.1190.10 1 293 9.9E-72 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS05155 7c5c6a7a3fe8327e69ff6b49b1d2633e 415 PIRSF PIRSF001563 1 415 2.0E-116 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 SPSF3K_RS05155 7c5c6a7a3fe8327e69ff6b49b1d2633e 415 SUPERFAMILY SSF53244 294 411 7.69E-20 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 SPSF3K_RS05155 7c5c6a7a3fe8327e69ff6b49b1d2633e 415 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 409 3.3E-116 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 SPSF3K_RS05155 7c5c6a7a3fe8327e69ff6b49b1d2633e 415 Gene3D G3DSA:3.90.190.20 294 415 1.0E-13 T 29-03-2018 SPSF3K_RS05155 7c5c6a7a3fe8327e69ff6b49b1d2633e 415 Pfam PF08245 Mur ligase middle domain 44 267 2.4E-11 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS05155 7c5c6a7a3fe8327e69ff6b49b1d2633e 415 SUPERFAMILY SSF53623 1 292 2.44E-81 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 SPSF3K_RS01815 74bf9bf4de85b8314dd20b72e4f5e8bf 150 Gene3D G3DSA:2.30.110.10 1 149 3.1E-22 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SPSF3K_RS01815 74bf9bf4de85b8314dd20b72e4f5e8bf 150 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 90 1.2E-11 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 SPSF3K_RS01815 74bf9bf4de85b8314dd20b72e4f5e8bf 150 SUPERFAMILY SSF50475 2 131 1.35E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 SPSF3K_RS07945 2348d91adebaaad0d6c78771d879d36a 255 Gene3D G3DSA:3.40.50.1000 72 181 2.4E-30 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07945 2348d91adebaaad0d6c78771d879d36a 255 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 228 3.2E-38 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SPSF3K_RS07945 2348d91adebaaad0d6c78771d879d36a 255 PIRSF PIRSF000915 1 107 1.0E-18 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SPSF3K_RS07945 2348d91adebaaad0d6c78771d879d36a 255 PIRSF PIRSF000915 98 251 4.1E-33 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SPSF3K_RS07945 2348d91adebaaad0d6c78771d879d36a 255 Pfam PF13242 HAD-hyrolase-like 179 251 3.0E-17 T 29-03-2018 SPSF3K_RS07945 2348d91adebaaad0d6c78771d879d36a 255 SUPERFAMILY SSF56784 3 252 1.63E-70 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS07945 2348d91adebaaad0d6c78771d879d36a 255 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 3 252 7.3E-114 T 29-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 SPSF3K_RS07945 2348d91adebaaad0d6c78771d879d36a 255 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 104 4.0E-20 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA SPSF3K_RS09515 715decff9869ca758b8a304848d94f98 258 Gene3D G3DSA:1.10.10.10 104 149 4.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09515 715decff9869ca758b8a304848d94f98 258 Hamap MF_01114 Regulatory protein RecX [recX]. 38 203 16.232 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 SPSF3K_RS09515 715decff9869ca758b8a304848d94f98 258 Pfam PF02631 RecX family 80 195 2.7E-26 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 SPSF3K_RS09515 715decff9869ca758b8a304848d94f98 258 Gene3D G3DSA:1.10.10.10 150 200 2.5E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09515 715decff9869ca758b8a304848d94f98 258 Gene3D G3DSA:1.10.10.10 213 258 1.1E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09515 715decff9869ca758b8a304848d94f98 258 Gene3D G3DSA:1.10.10.10 39 103 2.4E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01625 ebdd02b3f4cfa8e74f7c40b27861059e 96 Pfam PF01250 Ribosomal protein S6 3 93 5.3E-26 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01625 ebdd02b3f4cfa8e74f7c40b27861059e 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 96 22.0 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPSF3K_RS01625 ebdd02b3f4cfa8e74f7c40b27861059e 96 SUPERFAMILY SSF54995 1 95 4.45E-31 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01625 ebdd02b3f4cfa8e74f7c40b27861059e 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 95 5.0E-26 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01625 ebdd02b3f4cfa8e74f7c40b27861059e 96 Gene3D G3DSA:3.30.70.60 1 96 9.8E-29 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 SPSF3K_RS05115 33198c446dcc4f17af0777b6e2be1309 66 Pfam PF01632 Ribosomal protein L35 2 62 5.8E-21 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05115 33198c446dcc4f17af0777b6e2be1309 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS05115 33198c446dcc4f17af0777b6e2be1309 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.4E-17 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS05115 33198c446dcc4f17af0777b6e2be1309 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.4E-17 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS05115 33198c446dcc4f17af0777b6e2be1309 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.4E-17 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS05115 33198c446dcc4f17af0777b6e2be1309 66 SUPERFAMILY SSF143034 2 62 8.76E-20 T 29-03-2018 SPSF3K_RS05115 33198c446dcc4f17af0777b6e2be1309 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.721 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS05115 33198c446dcc4f17af0777b6e2be1309 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 5.1E-22 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS06040 7e7d80d74207f748f13519d90654a7dc 317 SUPERFAMILY SSF53448 6 257 5.63E-42 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS06040 7e7d80d74207f748f13519d90654a7dc 317 Gene3D G3DSA:3.90.550.10 6 233 8.8E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS06040 7e7d80d74207f748f13519d90654a7dc 317 Pfam PF00535 Glycosyl transferase family 2 9 172 8.9E-32 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SPSF3K_RS09395 1f8e710cbc12103a2b740ed71a38410e 316 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 4 316 4.6E-125 T 29-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS09395 1f8e710cbc12103a2b740ed71a38410e 316 SUPERFAMILY SSF47240 4 314 7.23E-82 T 29-03-2018 IPR009078 Ferritin-like superfamily SPSF3K_RS09395 1f8e710cbc12103a2b740ed71a38410e 316 Pfam PF00268 Ribonucleotide reductase, small chain 6 271 1.1E-68 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09395 1f8e710cbc12103a2b740ed71a38410e 316 Gene3D G3DSA:1.10.620.20 2 290 1.1E-61 T 29-03-2018 SPSF3K_RS08350 d606d012ea2b33035fa42e7cd010eff1 257 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 11 252 4.5E-76 T 29-03-2018 IPR005226 UPF0014 family SPSF3K_RS08350 d606d012ea2b33035fa42e7cd010eff1 257 Pfam PF03649 Uncharacterised protein family (UPF0014) 11 246 1.9E-79 T 29-03-2018 IPR005226 UPF0014 family SPSF3K_RS05130 1cf2feed349d9af011b08c8991a204bb 386 Gene3D G3DSA:2.30.130.10 3 63 1.2E-9 T 29-03-2018 IPR002478 PUA domain GO:0003723 SPSF3K_RS05130 1cf2feed349d9af011b08c8991a204bb 386 SUPERFAMILY SSF53335 74 379 4.03E-64 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS05130 1cf2feed349d9af011b08c8991a204bb 386 Gene3D G3DSA:3.40.50.150 173 385 1.9E-26 T 29-03-2018 SPSF3K_RS05130 1cf2feed349d9af011b08c8991a204bb 386 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 162 339 7.0E-28 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 SPSF3K_RS05130 1cf2feed349d9af011b08c8991a204bb 386 SUPERFAMILY SSF88697 1 66 3.98E-15 T 29-03-2018 IPR015947 PUA-like domain SPSF3K_RS05130 1cf2feed349d9af011b08c8991a204bb 386 Gene3D G3DSA:3.30.750.80 67 172 5.4E-22 T 29-03-2018 SPSF3K_RS04340 e2d7ddce68a28e9ff8fd1c403aaae6ae 208 Pfam PF04961 Formiminotransferase-cyclodeaminase 9 185 9.8E-63 T 29-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 SPSF3K_RS04340 e2d7ddce68a28e9ff8fd1c403aaae6ae 208 SUPERFAMILY SSF101262 3 205 1.57E-57 T 29-03-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 SPSF3K_RS08025 fd4d7c9eaff0470b28149d744e816343 261 SUPERFAMILY SSF53474 5 250 4.12E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS08025 fd4d7c9eaff0470b28149d744e816343 261 Pfam PF00756 Putative esterase 10 150 2.4E-16 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 SPSF3K_RS08025 fd4d7c9eaff0470b28149d744e816343 261 Gene3D G3DSA:3.40.50.1820 2 261 3.7E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS00755 2ba7029508156c82b5f9ba343f19c8a3 161 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 147 8.3E-32 T 29-03-2018 IPR002178 PTS EIIA type-2 domain SPSF3K_RS00755 2ba7029508156c82b5f9ba343f19c8a3 161 SUPERFAMILY SSF55804 6 147 1.57E-32 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS00755 2ba7029508156c82b5f9ba343f19c8a3 161 Gene3D G3DSA:3.40.930.10 2 149 2.0E-31 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 SPSF3K_RS10240 2cad4894833831115481d18dae59ff70 739 Pfam PF07238 PilZ domain 504 595 1.3E-9 T 29-03-2018 IPR009875 PilZ domain GO:0035438 SPSF3K_RS10240 2cad4894833831115481d18dae59ff70 739 Pfam PF00535 Glycosyl transferase family 2 84 258 1.7E-21 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SPSF3K_RS10240 2cad4894833831115481d18dae59ff70 739 Gene3D G3DSA:3.90.550.10 81 329 2.3E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS10240 2cad4894833831115481d18dae59ff70 739 SUPERFAMILY SSF141371 506 605 1.37E-5 T 29-03-2018 SPSF3K_RS10240 2cad4894833831115481d18dae59ff70 739 Gene3D G3DSA:2.40.10.220 505 612 1.3E-14 T 29-03-2018 SPSF3K_RS10240 2cad4894833831115481d18dae59ff70 739 Pfam PF03552 Cellulose synthase 266 455 1.7E-6 T 29-03-2018 IPR005150 Cellulose synthase GO:0016020|GO:0016760|GO:0030244 SPSF3K_RS10240 2cad4894833831115481d18dae59ff70 739 SUPERFAMILY SSF53448 80 368 2.0E-43 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS10530 d66ba30ee8b81dd8f093ee1970819cae 439 PIRSF PIRSF006603 11 439 1.7E-73 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS10530 d66ba30ee8b81dd8f093ee1970819cae 439 Pfam PF01554 MatE 27 181 6.6E-25 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS10530 d66ba30ee8b81dd8f093ee1970819cae 439 Pfam PF01554 MatE 241 402 3.9E-19 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS10530 d66ba30ee8b81dd8f093ee1970819cae 439 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 415 1.6E-55 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS08850 7d7ebe8cd0a46150c5216de3b23b40e5 152 Gene3D G3DSA:2.30.30.90 1 78 3.4E-10 T 29-03-2018 SPSF3K_RS08850 7d7ebe8cd0a46150c5216de3b23b40e5 152 Pfam PF04023 FeoA domain 2 70 3.7E-5 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SPSF3K_RS08850 7d7ebe8cd0a46150c5216de3b23b40e5 152 Pfam PF04023 FeoA domain 79 150 3.4E-17 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SPSF3K_RS08850 7d7ebe8cd0a46150c5216de3b23b40e5 152 SMART SM00899 1 71 1.6E-5 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SPSF3K_RS08850 7d7ebe8cd0a46150c5216de3b23b40e5 152 SMART SM00899 79 151 6.6E-23 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SPSF3K_RS08850 7d7ebe8cd0a46150c5216de3b23b40e5 152 SUPERFAMILY SSF50037 3 71 2.98E-9 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal SPSF3K_RS08850 7d7ebe8cd0a46150c5216de3b23b40e5 152 SUPERFAMILY SSF50037 83 150 2.17E-19 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal SPSF3K_RS08850 7d7ebe8cd0a46150c5216de3b23b40e5 152 Gene3D G3DSA:2.30.30.90 79 152 3.1E-20 T 29-03-2018 SPSF3K_RS08235 d1c622add77e8e9fbd243c1adc59a3c8 278 Gene3D G3DSA:1.10.3720.10 8 271 1.9E-37 T 29-03-2018 SPSF3K_RS08235 d1c622add77e8e9fbd243c1adc59a3c8 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 270 1.6E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS08235 d1c622add77e8e9fbd243c1adc59a3c8 278 SUPERFAMILY SSF161098 4 278 4.06E-62 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS09195 06871c036a48ce6280303bd8d5c8d275 182 Gene3D G3DSA:1.10.150.20 37 100 1.4E-9 T 29-03-2018 SPSF3K_RS09195 06871c036a48ce6280303bd8d5c8d275 182 SUPERFAMILY SSF47794 123 176 5.02E-9 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 SPSF3K_RS09195 06871c036a48ce6280303bd8d5c8d275 182 SUPERFAMILY SSF47794 62 112 5.49E-9 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 SPSF3K_RS09195 06871c036a48ce6280303bd8d5c8d275 182 Gene3D G3DSA:1.10.150.20 101 126 0.0014 T 29-03-2018 SPSF3K_RS09195 06871c036a48ce6280303bd8d5c8d275 182 Gene3D G3DSA:1.10.150.20 127 182 1.4E-9 T 29-03-2018 SPSF3K_RS09195 06871c036a48ce6280303bd8d5c8d275 182 Pfam PF14520 Helix-hairpin-helix domain 123 175 2.4E-6 T 29-03-2018 SPSF3K_RS09195 06871c036a48ce6280303bd8d5c8d275 182 Pfam PF14520 Helix-hairpin-helix domain 64 110 1.5E-7 T 29-03-2018 SPSF3K_RS09195 06871c036a48ce6280303bd8d5c8d275 182 SMART SM00278 157 176 0.28 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPSF3K_RS09195 06871c036a48ce6280303bd8d5c8d275 182 SMART SM00278 92 111 0.51 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPSF3K_RS05390 d7c6d675eb40deaf2b20c970d860361e 136 SUPERFAMILY SSF56420 15 136 6.93E-33 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS05390 d7c6d675eb40deaf2b20c970d860361e 136 Pfam PF01327 Polypeptide deformylase 11 136 1.5E-24 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS05390 d7c6d675eb40deaf2b20c970d860361e 136 Gene3D G3DSA:3.90.45.10 1 136 1.1E-31 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS05390 d7c6d675eb40deaf2b20c970d860361e 136 PRINTS PR01576 Peptide deformylase signature 113 136 2.2E-11 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS05390 d7c6d675eb40deaf2b20c970d860361e 136 PRINTS PR01576 Peptide deformylase signature 30 59 2.2E-11 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS05390 d7c6d675eb40deaf2b20c970d860361e 136 PRINTS PR01576 Peptide deformylase signature 83 94 2.2E-11 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS05390 d7c6d675eb40deaf2b20c970d860361e 136 PIRSF PIRSF004749 1 136 1.4E-31 T 29-03-2018 IPR023635 Peptide deformylase SPSF3K_RS00655 1c0485ecbc8a78f51fe66253b18e31ae 66 SMART SM00357 3 66 2.4E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 SPSF3K_RS00655 1c0485ecbc8a78f51fe66253b18e31ae 66 Gene3D G3DSA:2.40.50.140 1 66 2.6E-29 T 29-03-2018 SPSF3K_RS00655 1c0485ecbc8a78f51fe66253b18e31ae 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.3E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPSF3K_RS00655 1c0485ecbc8a78f51fe66253b18e31ae 66 SUPERFAMILY SSF50249 1 65 4.57E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS00655 1c0485ecbc8a78f51fe66253b18e31ae 66 PIRSF PIRSF002599 1 66 1.9E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 SPSF3K_RS00655 1c0485ecbc8a78f51fe66253b18e31ae 66 PRINTS PR00050 Cold shock protein signature 24 33 4.8E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPSF3K_RS00655 1c0485ecbc8a78f51fe66253b18e31ae 66 PRINTS PR00050 Cold shock protein signature 39 57 4.8E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPSF3K_RS00655 1c0485ecbc8a78f51fe66253b18e31ae 66 PRINTS PR00050 Cold shock protein signature 4 19 4.8E-20 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPSF3K_RS00655 1c0485ecbc8a78f51fe66253b18e31ae 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site SPSF3K_RS07485 dc0d5eacf52025cc6be1ab4017c481a9 384 Pfam PF10926 Protein of unknown function (DUF2800) 6 370 9.0E-120 T 29-03-2018 IPR021229 Protein of unknown function DUF2800 SPSF3K_RS04670 fff899ac52a7202e07effc450d4ed7af 409 Gene3D G3DSA:1.10.3080.10 2 407 8.5E-48 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS04670 fff899ac52a7202e07effc450d4ed7af 409 SUPERFAMILY SSF81340 6 399 4.71E-70 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS04670 fff899ac52a7202e07effc450d4ed7af 409 Pfam PF00654 Voltage gated chloride channel 58 388 1.1E-54 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 Pfam PF00245 Alkaline phosphatase 74 539 1.7E-72 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 ProSitePatterns PS00123 Alkaline phosphatase active site. 132 140 - T 29-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 SUPERFAMILY SSF53649 492 541 1.23E-100 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 SUPERFAMILY SSF53649 67 381 1.23E-100 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 Gene3D G3DSA:3.40.720.10 30 550 5.4E-111 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 PRINTS PR00113 Alkaline phosphatase signature 132 147 1.1E-35 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 PRINTS PR00113 Alkaline phosphatase signature 289 318 1.1E-35 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 PRINTS PR00113 Alkaline phosphatase signature 170 190 1.1E-35 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 PRINTS PR00113 Alkaline phosphatase signature 74 94 1.1E-35 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SPSF3K_RS02185 384438882a14c347336c9d9472130537 570 SMART SM00098 75 542 1.6E-38 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 SPSF3K_RS02020 84ca51126dceffde15cea74417abbf08 132 SUPERFAMILY SSF50249 1 132 8.91E-39 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS02020 84ca51126dceffde15cea74417abbf08 132 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 117 1.4E-29 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SPSF3K_RS02020 84ca51126dceffde15cea74417abbf08 132 Gene3D G3DSA:2.40.50.140 1 110 9.5E-33 T 29-03-2018 SPSF3K_RS02020 84ca51126dceffde15cea74417abbf08 132 Pfam PF00436 Single-strand binding protein family 3 102 1.7E-26 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 SPSF3K_RS02020 84ca51126dceffde15cea74417abbf08 132 Hamap MF_00984 Single-stranded DNA-binding protein. 2 106 29.493 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 SPSF3K_RS02020 84ca51126dceffde15cea74417abbf08 132 PIRSF PIRSF002070 1 129 4.7E-31 T 29-03-2018 SPSF3K_RS10155 f30580eb18b6b4d230d1257a27910e71 234 PIRSF PIRSF000709 1 103 3.4E-5 T 29-03-2018 SPSF3K_RS10155 f30580eb18b6b4d230d1257a27910e71 234 Gene3D G3DSA:3.40.50.1240 1 230 3.2E-43 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS10155 f30580eb18b6b4d230d1257a27910e71 234 SUPERFAMILY SSF53254 4 220 7.49E-48 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS10155 f30580eb18b6b4d230d1257a27910e71 234 SMART SM00855 5 182 4.8E-19 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS10155 f30580eb18b6b4d230d1257a27910e71 234 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 217 2.4E-30 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS03435 517e15588fe76e62023f46cb1a5afcb8 213 Gene3D G3DSA:1.20.58.410 3 90 0.0086 T 29-03-2018 SPSF3K_RS01080 ed894b35252f06c366efee6811f6780d 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 269 4.7E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01080 ed894b35252f06c366efee6811f6780d 277 SUPERFAMILY SSF161098 11 276 5.63E-64 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01080 ed894b35252f06c366efee6811f6780d 277 Gene3D G3DSA:1.10.3720.10 3 264 2.5E-36 T 29-03-2018 SPSF3K_RS00315 b16d9b1c6154950e779a88c2c6a23df0 323 PIRSF PIRSF006483 31 323 2.3E-95 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT SPSF3K_RS00315 b16d9b1c6154950e779a88c2c6a23df0 323 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 262 317 1.8E-11 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 SPSF3K_RS00315 b16d9b1c6154950e779a88c2c6a23df0 323 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 52 256 3.2E-56 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 SUPERFAMILY SSF74731 3 116 2.09E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 Pfam PF00453 Ribosomal protein L20 3 109 6.3E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 6.1E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 6.1E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 6.1E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.34 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 24 70 5.0E-13 T 29-03-2018 SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.4E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05120 0ac796b7cc3ac96b16027f3ea2790002 119 Gene3D G3DSA:1.10.1900.20 55 116 8.8E-29 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS09405 17cc807b76bc0bccad2bf8400a93e834 317 Pfam PF00268 Ribonucleotide reductase, small chain 11 274 5.3E-30 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS09405 17cc807b76bc0bccad2bf8400a93e834 317 Gene3D G3DSA:1.10.620.20 2 278 3.0E-31 T 29-03-2018 SPSF3K_RS09405 17cc807b76bc0bccad2bf8400a93e834 317 SUPERFAMILY SSF47240 8 283 8.92E-47 T 29-03-2018 IPR009078 Ferritin-like superfamily SPSF3K_RS04130 bbc9d784d9a901d99fd96b3e284b9794 234 Gene3D G3DSA:1.10.3720.10 3 226 8.0E-46 T 29-03-2018 SPSF3K_RS04130 bbc9d784d9a901d99fd96b3e284b9794 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 215 4.8E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04130 bbc9d784d9a901d99fd96b3e284b9794 234 SUPERFAMILY SSF161098 25 214 6.54E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04130 bbc9d784d9a901d99fd96b3e284b9794 234 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 123 3.8E-23 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPSF3K_RS01410 2492ba4fade147f0bd371939cadffda5 354 PIRSF PIRSF038991 1 353 5.1E-58 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 SPSF3K_RS01410 2492ba4fade147f0bd371939cadffda5 354 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 6 158 4.8E-30 T 29-03-2018 IPR017516 AbrB duplication SPSF3K_RS01410 2492ba4fade147f0bd371939cadffda5 354 Pfam PF05145 Transition state regulatory protein AbrB 195 350 1.0E-23 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 SPSF3K_RS01410 2492ba4fade147f0bd371939cadffda5 354 Pfam PF05145 Transition state regulatory protein AbrB 5 158 2.9E-24 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 SPSF3K_RS06790 fabfa4fa62e1662a954027d7dc3377d4 206 SUPERFAMILY SSF110849 90 159 2.62E-5 T 29-03-2018 IPR003115 ParB/Sulfiredoxin SPSF3K_RS03460 9c0bcd125b3606f2b27915f1dc7866c4 288 Pfam PF08708 Primase C terminal 1 (PriCT-1) 222 282 4.5E-7 T 29-03-2018 IPR014820 Primase, C-terminal 1 SPSF3K_RS03460 9c0bcd125b3606f2b27915f1dc7866c4 288 SMART SM00942 215 282 1.9E-18 T 29-03-2018 IPR014820 Primase, C-terminal 1 SPSF3K_RS00770 af962c50ded142ffb24edbfc3efdf636 235 SUPERFAMILY SSF53639 5 225 1.08E-70 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SPSF3K_RS00770 af962c50ded142ffb24edbfc3efdf636 235 SMART SM01007 10 200 4.0E-63 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SPSF3K_RS00770 af962c50ded142ffb24edbfc3efdf636 235 Gene3D G3DSA:3.40.225.10 4 233 1.2E-58 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SPSF3K_RS00770 af962c50ded142ffb24edbfc3efdf636 235 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 198 6.7E-46 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal SPSF3K_RS04230 4c9c1d6166ab57d76416b5e6844e8ac5 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 269 8.4E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04230 4c9c1d6166ab57d76416b5e6844e8ac5 272 Gene3D G3DSA:1.10.3720.10 5 272 3.0E-37 T 29-03-2018 SPSF3K_RS04230 4c9c1d6166ab57d76416b5e6844e8ac5 272 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 5 266 6.2E-76 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 SPSF3K_RS04230 4c9c1d6166ab57d76416b5e6844e8ac5 272 SUPERFAMILY SSF161098 9 262 7.3E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04510 8d163dcb21691e835cb68391be6470c4 372 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 184 195 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SPSF3K_RS04510 8d163dcb21691e835cb68391be6470c4 372 Pfam PF13484 4Fe-4S double cluster binding domain 184 246 1.5E-13 T 29-03-2018 SPSF3K_RS04510 8d163dcb21691e835cb68391be6470c4 372 Gene3D G3DSA:3.30.70.20 52 191 0.0061 T 29-03-2018 SPSF3K_RS04510 8d163dcb21691e835cb68391be6470c4 372 Pfam PF08331 Domain of unknown function (DUF1730) 54 131 6.9E-16 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 SPSF3K_RS04510 8d163dcb21691e835cb68391be6470c4 372 SUPERFAMILY SSF46548 157 246 2.25E-12 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 SPSF3K_RS04510 8d163dcb21691e835cb68391be6470c4 372 Gene3D G3DSA:3.30.70.20 192 323 1.4E-7 T 29-03-2018 SPSF3K_RS04510 8d163dcb21691e835cb68391be6470c4 372 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 7 336 1.3E-112 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 SPSF3K_RS04525 2d48f67827592136520b065dfb4ab5ff 309 PIRSF PIRSF003097 1 309 7.6E-74 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 SPSF3K_RS04525 2d48f67827592136520b065dfb4ab5ff 309 Pfam PF02687 FtsX-like permease family 213 308 5.3E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SPSF3K_RS00070 634efedf3a13dd83940ec323c2d76a18 414 SUPERFAMILY SSF63411 6 212 4.28E-11 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPSF3K_RS00070 634efedf3a13dd83940ec323c2d76a18 414 Gene3D G3DSA:3.30.830.10 8 217 3.6E-10 T 29-03-2018 SPSF3K_RS00070 634efedf3a13dd83940ec323c2d76a18 414 SUPERFAMILY SSF63411 242 401 8.83E-27 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPSF3K_RS00070 634efedf3a13dd83940ec323c2d76a18 414 Pfam PF05193 Peptidase M16 inactive domain 196 349 2.1E-17 T 29-03-2018 IPR007863 Peptidase M16, C-terminal SPSF3K_RS00070 634efedf3a13dd83940ec323c2d76a18 414 Gene3D G3DSA:3.30.830.10 220 406 1.3E-23 T 29-03-2018 SPSF3K_RS00205 93423af53190ae34921124942b89922b 108 Gene3D G3DSA:1.10.10.10 4 94 1.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00205 93423af53190ae34921124942b89922b 108 Pfam PF03551 Transcriptional regulator PadR-like family 14 81 3.5E-19 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SPSF3K_RS00205 93423af53190ae34921124942b89922b 108 SUPERFAMILY SSF46785 3 105 1.89E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07830 8814efdaa2395a909d9defde61dd3982 131 Pfam PF07681 DoxX 12 86 1.3E-9 T 29-03-2018 IPR032808 DoxX family SPSF3K_RS01030 884a843854cc5dc9a42bf26b37a0ac14 270 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 239 29.253 T 29-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes SPSF3K_RS01030 884a843854cc5dc9a42bf26b37a0ac14 270 PRINTS PR00701 60kDa inner membrane protein signature 202 225 6.4E-9 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPSF3K_RS01030 884a843854cc5dc9a42bf26b37a0ac14 270 PRINTS PR00701 60kDa inner membrane protein signature 118 141 6.4E-9 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPSF3K_RS01030 884a843854cc5dc9a42bf26b37a0ac14 270 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 52 235 4.3E-58 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SPSF3K_RS01030 884a843854cc5dc9a42bf26b37a0ac14 270 Pfam PF02096 60Kd inner membrane protein 54 235 1.0E-53 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPSF3K_RS06830 b2cf5051cbf9377edc8cdc7056914cfd 447 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 9 443 5.0E-208 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 SPSF3K_RS06830 b2cf5051cbf9377edc8cdc7056914cfd 447 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 349 372 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 SPSF3K_RS06830 b2cf5051cbf9377edc8cdc7056914cfd 447 Gene3D G3DSA:3.50.50.60 9 387 1.3E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06830 b2cf5051cbf9377edc8cdc7056914cfd 447 Pfam PF01134 Glucose inhibited division protein A 9 380 2.4E-113 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 SPSF3K_RS06830 b2cf5051cbf9377edc8cdc7056914cfd 447 SUPERFAMILY SSF51905 11 379 5.07E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS06830 b2cf5051cbf9377edc8cdc7056914cfd 447 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 9 447 35.936 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 SPSF3K_RS09830 9dbbb00ff61506f6385d3c0f23994a5c 214 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 203 3.5E-58 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SPSF3K_RS09830 9dbbb00ff61506f6385d3c0f23994a5c 214 ProSitePatterns PS00958 Transaldolase active site. 80 96 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SPSF3K_RS09830 9dbbb00ff61506f6385d3c0f23994a5c 214 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SPSF3K_RS09830 9dbbb00ff61506f6385d3c0f23994a5c 214 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 211 2.0E-89 T 29-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SPSF3K_RS09830 9dbbb00ff61506f6385d3c0f23994a5c 214 SUPERFAMILY SSF51569 1 212 2.09E-79 T 29-03-2018 SPSF3K_RS09830 9dbbb00ff61506f6385d3c0f23994a5c 214 Gene3D G3DSA:3.20.20.70 1 214 4.6E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS09830 9dbbb00ff61506f6385d3c0f23994a5c 214 Hamap MF_00494 Probable transaldolase [tal]. 1 214 46.884 T 29-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SPSF3K_RS10495 b5d4411ffe87562e51081b8288900a85 114 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 9 111 1.5E-45 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10495 b5d4411ffe87562e51081b8288900a85 114 Pfam PF00237 Ribosomal protein L22p/L17e 9 111 1.0E-39 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10495 b5d4411ffe87562e51081b8288900a85 114 SUPERFAMILY SSF54843 6 114 1.18E-44 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10495 b5d4411ffe87562e51081b8288900a85 114 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 5 114 29.848 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10495 b5d4411ffe87562e51081b8288900a85 114 ProSitePatterns PS00464 Ribosomal protein L22 signature. 87 111 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10495 b5d4411ffe87562e51081b8288900a85 114 Gene3D G3DSA:3.90.470.10 1 114 8.6E-47 T 29-03-2018 SPSF3K_RS07320 18c9586c8899cd06d621cbe75dcd21e3 92 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 3 90 5.7E-14 T 29-03-2018 IPR006485 Bacteriophage holin SPSF3K_RS07320 18c9586c8899cd06d621cbe75dcd21e3 92 Pfam PF04531 Bacteriophage holin 3 91 2.0E-23 T 29-03-2018 IPR006485 Bacteriophage holin SPSF3K_RS08215 7f6612cffbfe9c81041b85916d162431 502 SUPERFAMILY SSF51445 3 495 2.38E-157 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS08215 7f6612cffbfe9c81041b85916d162431 502 Gene3D G3DSA:3.20.20.80 1 496 4.3E-151 T 29-03-2018 SPSF3K_RS08215 7f6612cffbfe9c81041b85916d162431 502 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 2 495 5.3E-98 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SPSF3K_RS08215 7f6612cffbfe9c81041b85916d162431 502 Pfam PF02446 4-alpha-glucanotransferase 10 473 9.3E-147 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SPSF3K_RS03300 19d0b03cf4acdf0873d72dd9d036f97e 92 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SPSF3K_RS03300 19d0b03cf4acdf0873d72dd9d036f97e 92 Pfam PF00708 Acylphosphatase 4 89 1.4E-21 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SPSF3K_RS03300 19d0b03cf4acdf0873d72dd9d036f97e 92 SUPERFAMILY SSF54975 1 89 7.63E-20 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SPSF3K_RS03300 19d0b03cf4acdf0873d72dd9d036f97e 92 Gene3D G3DSA:3.30.70.100 1 92 6.1E-21 T 29-03-2018 SPSF3K_RS01895 a0cad1acf149279f5299f7758c6ea259 147 Pfam PF01047 MarR family 36 92 1.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS01895 a0cad1acf149279f5299f7758c6ea259 147 Gene3D G3DSA:1.10.10.10 4 135 5.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01895 a0cad1acf149279f5299f7758c6ea259 147 SMART SM00347 29 131 2.0E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS01895 a0cad1acf149279f5299f7758c6ea259 147 SUPERFAMILY SSF46785 11 119 9.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07215 f485c3eaed3601a32d8dc46dfc53655c 209 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS07215 f485c3eaed3601a32d8dc46dfc53655c 209 SUPERFAMILY SSF52540 1 206 1.62E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07215 f485c3eaed3601a32d8dc46dfc53655c 209 SMART SM00382 26 209 7.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS07215 f485c3eaed3601a32d8dc46dfc53655c 209 Pfam PF00005 ABC transporter 18 162 1.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS07215 f485c3eaed3601a32d8dc46dfc53655c 209 Gene3D G3DSA:3.40.50.300 1 208 6.4E-63 T 29-03-2018 SPSF3K_RS08245 22bfbabb1925de05e96d658455326895 424 PIRSF PIRSF021438 1 393 3.6E-128 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes SPSF3K_RS08245 22bfbabb1925de05e96d658455326895 424 PIRSF PIRSF021438 391 422 150.0 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes SPSF3K_RS08245 22bfbabb1925de05e96d658455326895 424 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 9 390 2.9E-127 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes SPSF3K_RS08245 22bfbabb1925de05e96d658455326895 424 Pfam PF04914 DltD protein 42 390 3.6E-115 T 29-03-2018 IPR006998 DltD SPSF3K_RS10255 b5848529d911fe463c7def2327a05999 445 Gene3D G3DSA:3.90.550.10 45 328 3.0E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS10255 b5848529d911fe463c7def2327a05999 445 SUPERFAMILY SSF53448 62 344 3.94E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS10255 b5848529d911fe463c7def2327a05999 445 Pfam PF00535 Glycosyl transferase family 2 70 238 1.2E-29 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SPSF3K_RS07970 1390bf7e78372d0e9ef544ce32b4114d 317 Pfam PF07949 YbbR-like protein 151 223 2.2E-7 T 29-03-2018 IPR012505 YbbR-like SPSF3K_RS07970 1390bf7e78372d0e9ef544ce32b4114d 317 Pfam PF07949 YbbR-like protein 51 134 3.2E-6 T 29-03-2018 IPR012505 YbbR-like SPSF3K_RS07970 1390bf7e78372d0e9ef544ce32b4114d 317 Pfam PF07949 YbbR-like protein 236 312 4.9E-10 T 29-03-2018 IPR012505 YbbR-like SPSF3K_RS00960 4d517f5b634d05636374d7079360841f 119 Pfam PF04304 Protein of unknown function (DUF454) 3 114 4.5E-35 T 29-03-2018 IPR007401 Protein of unknown function DUF454 SPSF3K_RS00960 4d517f5b634d05636374d7079360841f 119 PIRSF PIRSF016789 2 119 2.2E-36 T 29-03-2018 IPR007401 Protein of unknown function DUF454 SPSF3K_RS08070 cc5a2e9081aca15a3615f66ee6b009df 393 Pfam PF01594 AI-2E family transporter 35 366 1.2E-67 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 Pfam PF07690 Major Facilitator Superfamily 20 406 8.4E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 Gene3D G3DSA:1.20.1250.20 4 201 2.5E-27 T 29-03-2018 SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 SUPERFAMILY SSF103473 245 447 1.28E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 SUPERFAMILY SSF103473 7 198 1.28E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 3.4E-8 T 29-03-2018 SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 204 222 3.4E-8 T 29-03-2018 SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 3.4E-8 T 29-03-2018 SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 3.4E-8 T 29-03-2018 SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 3.4E-8 T 29-03-2018 SPSF3K_RS04190 485a5741d2c8a1baff1a4ff4bba3f318 451 Gene3D G3DSA:1.20.1250.20 256 450 2.6E-20 T 29-03-2018 SPSF3K_RS02190 6ad2ef486e2639a85dbd23c5c58932ca 347 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 174 183 - T 29-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 SPSF3K_RS02190 6ad2ef486e2639a85dbd23c5c58932ca 347 SUPERFAMILY SSF74650 7 346 8.79E-102 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SPSF3K_RS02190 6ad2ef486e2639a85dbd23c5c58932ca 347 Pfam PF01263 Aldose 1-epimerase 17 344 6.6E-86 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 SPSF3K_RS02190 6ad2ef486e2639a85dbd23c5c58932ca 347 Gene3D G3DSA:2.70.98.10 4 347 3.3E-107 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 SPSF3K_RS02190 6ad2ef486e2639a85dbd23c5c58932ca 347 PIRSF PIRSF005096 1 347 9.5E-119 T 29-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 SPSF3K_RS08420 2751ba3732807b5b82bb6b640f27ccc2 107 Pfam PF03551 Transcriptional regulator PadR-like family 24 86 1.2E-14 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal SPSF3K_RS08420 2751ba3732807b5b82bb6b640f27ccc2 107 Gene3D G3DSA:1.10.10.10 4 104 1.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08420 2751ba3732807b5b82bb6b640f27ccc2 107 SUPERFAMILY SSF46785 16 96 4.58E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00085 ca1112f445053ac427b20e2ccc567bed 180 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 74 6.6E-17 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SPSF3K_RS00085 ca1112f445053ac427b20e2ccc567bed 180 PIRSF PIRSF000847 2 180 8.7E-50 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 SPSF3K_RS00085 ca1112f445053ac427b20e2ccc567bed 180 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 6 169 4.9E-52 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 SPSF3K_RS00085 ca1112f445053ac427b20e2ccc567bed 180 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 52 74 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 277 364 3.7E-21 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 Gene3D G3DSA:3.20.20.10 27 261 7.6E-44 T 29-03-2018 IPR029066 PLP-binding barrel SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 SUPERFAMILY SSF51419 19 278 5.56E-55 T 29-03-2018 IPR029066 PLP-binding barrel SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 SUPERFAMILY SSF50621 251 405 1.65E-44 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 30 275 4.2E-27 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 Gene3D G3DSA:2.40.37.10 262 410 1.2E-36 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 71 83 3.1E-10 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 364 377 3.1E-10 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 51 69 3.1E-10 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 266 285 3.1E-10 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 152 161 5.2E-8 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 293 311 5.2E-8 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS03320 e0901b088593544ce3dd24e1997068d7 412 PRINTS PR01181 Diaminopimelate decarboxylase signature 374 396 5.2E-8 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 SPSF3K_RS07690 dc9a98d5cc620eb8c9bb7f3e0ecfc337 402 Pfam PF04932 O-Antigen ligase 196 333 1.4E-10 T 29-03-2018 IPR007016 O-antigen ligase-related SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 161 29.915 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 Gene3D G3DSA:3.40.50.620 1 161 3.1E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 5 158 1.0E-4 T 29-03-2018 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 88 104 5.3E-32 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 5.3E-32 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 115 137 5.3E-32 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 5.3E-32 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 51 75 5.3E-32 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 6 159 1.1E-54 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 SUPERFAMILY SSF52374 3 159 6.17E-39 T 29-03-2018 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 Pfam PF01467 Cytidylyltransferase-like 7 136 1.6E-14 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPSF3K_RS09040 c27ee0d53b2e3928636228d1f110e397 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 62 1.0E-15 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPSF3K_RS08575 b2ce464fa149f20827dcecb80f6893a4 314 SUPERFAMILY SSF54534 147 239 2.28E-6 T 29-03-2018 SPSF3K_RS08575 b2ce464fa149f20827dcecb80f6893a4 314 Gene3D G3DSA:3.10.50.40 141 242 9.4E-8 T 29-03-2018 SPSF3K_RS08575 b2ce464fa149f20827dcecb80f6893a4 314 SUPERFAMILY SSF109998 33 174 3.18E-18 T 29-03-2018 IPR027304 Trigger factor/SurA domain SPSF3K_RS08575 b2ce464fa149f20827dcecb80f6893a4 314 Hamap MF_01145 Foldase protein PrsA [prsA]. 6 298 19.195 T 29-03-2018 IPR023059 Foldase protein PrsA GO:0003755 SPSF3K_RS08575 b2ce464fa149f20827dcecb80f6893a4 314 Pfam PF13145 PPIC-type PPIASE domain 133 252 7.6E-13 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 SPSF3K_RS08575 b2ce464fa149f20827dcecb80f6893a4 314 Gene3D G3DSA:1.10.4030.10 24 130 4.6E-7 T 29-03-2018 SPSF3K_RS04555 7bdab529340e770e9c27a754b0f5d67b 297 Pfam PF03668 P-loop ATPase protein family 7 289 1.6E-103 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 SPSF3K_RS04555 7bdab529340e770e9c27a754b0f5d67b 297 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 7 289 41.981 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 SPSF3K_RS04555 7bdab529340e770e9c27a754b0f5d67b 297 PIRSF PIRSF005052 7 292 1.6E-107 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 SPSF3K_RS04555 7bdab529340e770e9c27a754b0f5d67b 297 SUPERFAMILY SSF52540 9 161 1.31E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS04555 7bdab529340e770e9c27a754b0f5d67b 297 Gene3D G3DSA:3.40.50.300 2 166 3.4E-8 T 29-03-2018 SPSF3K_RS03025 ba7ae9b33305f2df92923dd89e5f3e94 420 SUPERFAMILY SSF101960 4 418 2.09E-114 T 29-03-2018 SPSF3K_RS03025 ba7ae9b33305f2df92923dd89e5f3e94 420 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 132 408 4.9E-80 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 SPSF3K_RS03025 ba7ae9b33305f2df92923dd89e5f3e94 420 Pfam PF01458 Uncharacterized protein family (UPF0051) 167 392 8.7E-58 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SPSF3K_RS06380 908ccc134741636db0754d664c702d72 144 SUPERFAMILY SSF55729 1 138 2.82E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS06380 908ccc134741636db0754d664c702d72 144 Gene3D G3DSA:3.40.630.30 1 144 7.4E-23 T 29-03-2018 SPSF3K_RS06380 908ccc134741636db0754d664c702d72 144 Pfam PF00583 Acetyltransferase (GNAT) family 37 130 2.5E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS03620 df69982dfcad649fabd6d6d15789600e 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 251 3.6E-11 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal SPSF3K_RS03620 df69982dfcad649fabd6d6d15789600e 254 SMART SM00382 28 228 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS03620 df69982dfcad649fabd6d6d15789600e 254 Pfam PF00005 ABC transporter 21 179 9.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS03620 df69982dfcad649fabd6d6d15789600e 254 SUPERFAMILY SSF52540 3 250 1.38E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03620 df69982dfcad649fabd6d6d15789600e 254 Gene3D G3DSA:3.40.50.300 1 251 5.0E-62 T 29-03-2018 SPSF3K_RS06750 17942a6c275c0806da3eff79dd0b644c 298 Pfam PF05598 Transposase domain (DUF772) 51 120 8.5E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal SPSF3K_RS06750 17942a6c275c0806da3eff79dd0b644c 298 Pfam PF01609 Transposase DDE domain 135 295 8.7E-30 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 SPSF3K_RS06990 aa53e0272ff843a9b019db8b1dc5768c 318 Gene3D G3DSA:1.10.3470.10 3 306 1.5E-43 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS06990 aa53e0272ff843a9b019db8b1dc5768c 318 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 296 3.9E-37 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPSF3K_RS09320 5683906a06eb2c6fec4c863c232f1edb 249 SUPERFAMILY SSF51569 3 248 1.28E-73 T 29-03-2018 SPSF3K_RS09320 5683906a06eb2c6fec4c863c232f1edb 249 Pfam PF01487 Type I 3-dehydroquinase 21 245 5.6E-65 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SPSF3K_RS09320 5683906a06eb2c6fec4c863c232f1edb 249 ProSitePatterns PS01028 Dehydroquinase class I active site. 114 144 - T 29-03-2018 IPR018508 3-dehydroquinate dehydratase, active site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SPSF3K_RS09320 5683906a06eb2c6fec4c863c232f1edb 249 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 18 248 37.277 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SPSF3K_RS09320 5683906a06eb2c6fec4c863c232f1edb 249 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 18 244 1.9E-76 T 29-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 SPSF3K_RS09320 5683906a06eb2c6fec4c863c232f1edb 249 Gene3D G3DSA:3.20.20.70 2 249 8.2E-79 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS11020 f1fcc42299b0c8bd63a02099d0ebb20f 195 Gene3D G3DSA:1.10.10.10 1 51 4.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS11020 f1fcc42299b0c8bd63a02099d0ebb20f 195 Pfam PF04394 Protein of unknown function, DUF536 96 123 2.3E-4 T 29-03-2018 IPR007489 Domain of unknown function DUF536 SPSF3K_RS11020 f1fcc42299b0c8bd63a02099d0ebb20f 195 Gene3D G3DSA:1.10.1660.10 83 181 0.19 T 29-03-2018 SPSF3K_RS10940 f1fcc42299b0c8bd63a02099d0ebb20f 195 Gene3D G3DSA:1.10.10.10 1 51 4.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10940 f1fcc42299b0c8bd63a02099d0ebb20f 195 Pfam PF04394 Protein of unknown function, DUF536 96 123 2.3E-4 T 29-03-2018 IPR007489 Domain of unknown function DUF536 SPSF3K_RS10940 f1fcc42299b0c8bd63a02099d0ebb20f 195 Gene3D G3DSA:1.10.1660.10 83 181 0.19 T 29-03-2018 SPSF3K_RS04810 ee4f9bb1e1a00c67b3ad90a5bca91a23 205 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 5 205 1.4E-48 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04810 ee4f9bb1e1a00c67b3ad90a5bca91a23 205 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 3 205 19.584 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04810 ee4f9bb1e1a00c67b3ad90a5bca91a23 205 Pfam PF01813 ATP synthase subunit D 12 205 7.6E-55 T 29-03-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04810 ee4f9bb1e1a00c67b3ad90a5bca91a23 205 Gene3D G3DSA:1.20.5.340 3 196 6.2E-6 T 29-03-2018 SPSF3K_RS06625 325c0c3a15d6f3e90409f0c636c5cbc1 230 Gene3D G3DSA:1.10.3100.10 1 141 1.4E-23 T 29-03-2018 IPR027910 YdiL-like domain SPSF3K_RS06625 325c0c3a15d6f3e90409f0c636c5cbc1 230 Pfam PF00717 Peptidase S24-like 146 206 1.2E-12 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SPSF3K_RS06625 325c0c3a15d6f3e90409f0c636c5cbc1 230 SUPERFAMILY SSF47413 2 65 2.95E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS06625 325c0c3a15d6f3e90409f0c636c5cbc1 230 SUPERFAMILY SSF51306 108 224 5.49E-24 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SPSF3K_RS06625 325c0c3a15d6f3e90409f0c636c5cbc1 230 Gene3D G3DSA:2.10.109.10 142 230 1.4E-16 T 29-03-2018 SPSF3K_RS06625 325c0c3a15d6f3e90409f0c636c5cbc1 230 Pfam PF01381 Helix-turn-helix 7 57 2.5E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS06625 325c0c3a15d6f3e90409f0c636c5cbc1 230 SMART SM00530 6 61 6.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS02515 8997ab6b8bea7832ac4b0af3b4911b5f 538 SUPERFAMILY SSF51011 466 534 2.11E-12 T 29-03-2018 SPSF3K_RS02515 8997ab6b8bea7832ac4b0af3b4911b5f 538 SUPERFAMILY SSF51445 4 461 1.55E-142 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS02515 8997ab6b8bea7832ac4b0af3b4911b5f 538 SMART SM00642 13 402 3.3E-150 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS02515 8997ab6b8bea7832ac4b0af3b4911b5f 538 Gene3D G3DSA:2.60.40.1180 487 535 6.6E-9 T 29-03-2018 SPSF3K_RS02515 8997ab6b8bea7832ac4b0af3b4911b5f 538 Pfam PF00128 Alpha amylase, catalytic domain 28 359 2.0E-119 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPSF3K_RS02515 8997ab6b8bea7832ac4b0af3b4911b5f 538 Pfam PF11941 Domain of unknown function (DUF3459) 448 531 7.3E-6 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SPSF3K_RS02515 8997ab6b8bea7832ac4b0af3b4911b5f 538 Gene3D G3DSA:3.20.20.80 2 246 7.8E-69 T 29-03-2018 SPSF3K_RS02515 8997ab6b8bea7832ac4b0af3b4911b5f 538 Gene3D G3DSA:3.20.20.80 247 486 6.2E-59 T 29-03-2018 SPSF3K_RS01005 58c6b6ecf9da380af3f5c77c8a43af85 343 Pfam PF14501 GHKL domain 240 305 1.8E-7 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain SPSF3K_RS01005 58c6b6ecf9da380af3f5c77c8a43af85 343 Gene3D G3DSA:1.10.287.130 116 189 5.5E-5 T 29-03-2018 SPSF3K_RS01365 b52b0089170eb79df8e6484fd8737752 208 Pfam PF13460 NAD(P)H-binding 7 144 6.9E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS01365 b52b0089170eb79df8e6484fd8737752 208 Gene3D G3DSA:3.40.50.720 1 196 8.4E-21 T 29-03-2018 SPSF3K_RS01365 b52b0089170eb79df8e6484fd8737752 208 SUPERFAMILY SSF51735 1 189 1.25E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS05840 135799a7a7bb408dfcfd48f08bf1dbe6 289 SUPERFAMILY SSF81301 4 114 4.53E-12 T 29-03-2018 SPSF3K_RS05840 135799a7a7bb408dfcfd48f08bf1dbe6 289 Gene3D G3DSA:3.30.460.10 7 174 5.4E-27 T 29-03-2018 SPSF3K_RS05840 135799a7a7bb408dfcfd48f08bf1dbe6 289 Pfam PF01909 Nucleotidyltransferase domain 6 114 2.1E-14 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 SPSF3K_RS06890 c563cebaade8b6711e3d42c7a8918cd4 295 Gene3D G3DSA:3.30.390.50 230 294 6.9E-10 T 29-03-2018 SPSF3K_RS06890 c563cebaade8b6711e3d42c7a8918cd4 295 Gene3D G3DSA:3.30.930.10 1 229 5.5E-54 T 29-03-2018 SPSF3K_RS06890 c563cebaade8b6711e3d42c7a8918cd4 295 SUPERFAMILY SSF55681 1 223 9.94E-59 T 29-03-2018 SPSF3K_RS06890 c563cebaade8b6711e3d42c7a8918cd4 295 Pfam PF03099 Biotin/lipoate A/B protein ligase family 54 146 2.4E-7 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SPSF3K_RS06890 c563cebaade8b6711e3d42c7a8918cd4 295 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 226 290 2.0E-7 T 29-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 SPSF3K_RS06890 c563cebaade8b6711e3d42c7a8918cd4 295 SUPERFAMILY SSF82649 225 289 8.89E-9 T 29-03-2018 SPSF3K_RS06890 c563cebaade8b6711e3d42c7a8918cd4 295 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 5 292 4.1E-68 T 29-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 SPSF3K_RS06870 fb9701b3ed8e30b2d491c5997b20b2a3 181 Gene3D G3DSA:2.160.10.10 1 181 1.8E-44 T 29-03-2018 SPSF3K_RS06870 fb9701b3ed8e30b2d491c5997b20b2a3 181 Pfam PF12464 Maltose acetyltransferase 6 55 8.1E-15 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 SPSF3K_RS06870 fb9701b3ed8e30b2d491c5997b20b2a3 181 SUPERFAMILY SSF51161 2 179 9.98E-46 T 29-03-2018 IPR011004 Trimeric LpxA-like SPSF3K_RS06870 fb9701b3ed8e30b2d491c5997b20b2a3 181 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 127 162 4.3E-11 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS06870 fb9701b3ed8e30b2d491c5997b20b2a3 181 SMART SM01266 4 56 1.8E-17 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 SPSF3K_RS00795 cb9f52f72c618eed7ca8698293519008 575 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 269 1.4E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS00795 cb9f52f72c618eed7ca8698293519008 575 Gene3D G3DSA:3.40.190.10 315 418 1.7E-17 T 29-03-2018 SPSF3K_RS00795 cb9f52f72c618eed7ca8698293519008 575 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 323 564 1.1E-66 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SPSF3K_RS00795 cb9f52f72c618eed7ca8698293519008 575 SUPERFAMILY SSF161098 88 272 3.01E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS00795 cb9f52f72c618eed7ca8698293519008 575 Gene3D G3DSA:3.40.190.100 419 526 2.4E-36 T 29-03-2018 SPSF3K_RS00795 cb9f52f72c618eed7ca8698293519008 575 SUPERFAMILY SSF53850 320 575 7.61E-82 T 29-03-2018 SPSF3K_RS00795 cb9f52f72c618eed7ca8698293519008 575 Gene3D G3DSA:1.10.3720.10 42 286 2.5E-37 T 29-03-2018 SPSF3K_RS03805 d12c9c853c3dff164aef27d7247a14a1 239 SUPERFAMILY SSF52540 1 234 5.62E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03805 d12c9c853c3dff164aef27d7247a14a1 239 SMART SM00382 27 211 4.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS03805 d12c9c853c3dff164aef27d7247a14a1 239 Pfam PF00005 ABC transporter 18 163 1.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS03805 d12c9c853c3dff164aef27d7247a14a1 239 Gene3D G3DSA:3.40.50.300 1 233 2.9E-56 T 29-03-2018 SPSF3K_RS03805 d12c9c853c3dff164aef27d7247a14a1 239 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS04200 7d9b6adc63a06422a5d1d474661dfd72 301 Pfam PF03773 Predicted permease 15 298 3.8E-69 T 29-03-2018 IPR005524 Predicted permease DUF318 SPSF3K_RS03560 1ffd217889661da171ead88bd3f0802d 339 Pfam PF01032 FecCD transport family 27 336 4.5E-81 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 SPSF3K_RS03560 1ffd217889661da171ead88bd3f0802d 339 SUPERFAMILY SSF81345 11 336 1.83E-71 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SPSF3K_RS03560 1ffd217889661da171ead88bd3f0802d 339 Gene3D G3DSA:1.10.3470.10 12 339 2.0E-56 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS07370 88311704df6cfbd594f7cdbeccd81d5f 115 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 9 109 3.7E-23 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor SPSF3K_RS07370 88311704df6cfbd594f7cdbeccd81d5f 115 Pfam PF05521 Phage head-tail joining protein 11 96 7.7E-13 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 SUPERFAMILY SSF81338 5 169 2.88E-59 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 SUPERFAMILY SSF81338 195 280 2.88E-59 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 Pfam PF00230 Major intrinsic protein 8 274 4.2E-38 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 Gene3D G3DSA:1.20.1080.10 1 282 3.4E-78 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 ProSitePatterns PS00221 MIP family signature. 67 75 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 PRINTS PR00783 Major intrinsic protein family signature 86 105 1.3E-38 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 PRINTS PR00783 Major intrinsic protein family signature 208 230 1.3E-38 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 PRINTS PR00783 Major intrinsic protein family signature 7 26 1.3E-38 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 PRINTS PR00783 Major intrinsic protein family signature 259 279 1.3E-38 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 PRINTS PR00783 Major intrinsic protein family signature 49 73 1.3E-38 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS01535 694120e6beedcbc67e8339ff6a5f29e8 282 PRINTS PR00783 Major intrinsic protein family signature 150 168 1.3E-38 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS09630 424ceb0e2582f041db1628c2f08d3af3 334 PIRSF PIRSF037431 1 334 1.3E-118 T 29-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 SPSF3K_RS09630 424ceb0e2582f041db1628c2f08d3af3 334 SUPERFAMILY SSF55874 205 326 3.54E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS09630 424ceb0e2582f041db1628c2f08d3af3 334 Gene3D G3DSA:3.30.565.10 197 334 2.0E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS09630 424ceb0e2582f041db1628c2f08d3af3 334 Pfam PF07730 Histidine kinase 132 200 3.1E-16 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SPSF3K_RS09665 ffba643563e1ca53ed4ad36a6983e30d 105 SUPERFAMILY SSF63562 2 78 1.67E-21 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SPSF3K_RS09665 ffba643563e1ca53ed4ad36a6983e30d 105 SMART SM01409 9 61 5.3E-11 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SPSF3K_RS09665 ffba643563e1ca53ed4ad36a6983e30d 105 Pfam PF01192 RNA polymerase Rpb6 10 59 2.3E-9 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SPSF3K_RS09665 ffba643563e1ca53ed4ad36a6983e30d 105 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 2 59 1.4E-12 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS09665 ffba643563e1ca53ed4ad36a6983e30d 105 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 62 13.866 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPSF3K_RS09665 ffba643563e1ca53ed4ad36a6983e30d 105 Gene3D G3DSA:3.90.940.10 2 100 1.1E-24 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 SPSF3K_RS05805 a84b0364d96c9507f654fee34519a93b 89 Gene3D G3DSA:1.10.1220.10 29 65 7.1E-15 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 SPSF3K_RS05805 a84b0364d96c9507f654fee34519a93b 89 SUPERFAMILY SSF47598 24 71 2.15E-24 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 SPSF3K_RS05805 a84b0364d96c9507f654fee34519a93b 89 Pfam PF07764 Omega Transcriptional Repressor 2 71 1.5E-47 T 29-03-2018 IPR011686 Omega transcriptional repressor SPSF3K_RS03210 6d5128196ea2dfa560eef99b0d67bb30 458 Pfam PF02386 Cation transport protein 37 449 1.9E-60 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 SPSF3K_RS04410 194a70cfbaa21d9b9e6970f51cf297cd 168 Pfam PF12822 ECF transporter, substrate-specific component 5 160 3.1E-9 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 SPSF3K_RS09910 3b133a4ac76df3af3dd6f950b006394f 185 SUPERFAMILY SSF46689 21 85 2.05E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS09910 3b133a4ac76df3af3dd6f950b006394f 185 Gene3D G3DSA:1.10.10.60 17 61 8.7E-12 T 29-03-2018 SPSF3K_RS09910 3b133a4ac76df3af3dd6f950b006394f 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 74 4.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPSF3K_RS09910 3b133a4ac76df3af3dd6f950b006394f 185 Gene3D G3DSA:1.10.10.60 62 150 3.4E-10 T 29-03-2018 SPSF3K_RS10665 84258193c632e1286c4a604f874e4684 166 Pfam PF04093 rod shape-determining protein MreD 7 158 4.1E-10 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 SPSF3K_RS06705 2949f72598a0236f1d44862d424449b2 260 Pfam PF06738 Putative threonine/serine exporter 12 252 1.3E-51 T 29-03-2018 IPR010619 Putative threonine/serine exporter SPSF3K_RS09720 b98fc34e4f1d8bc2372f99864bb8da6e 200 Gene3D G3DSA:3.40.1350.10 31 195 1.6E-58 T 29-03-2018 SPSF3K_RS09720 b98fc34e4f1d8bc2372f99864bb8da6e 200 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 200 97.014 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 SPSF3K_RS09720 b98fc34e4f1d8bc2372f99864bb8da6e 200 TIGRFAM TIGR00648 recU: recombination protein U 29 194 4.2E-61 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 SPSF3K_RS09720 b98fc34e4f1d8bc2372f99864bb8da6e 200 Pfam PF03838 Recombination protein U 30 192 2.0E-63 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 SPSF3K_RS09720 b98fc34e4f1d8bc2372f99864bb8da6e 200 PIRSF PIRSF037785 21 200 1.1E-77 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 SPSF3K_RS09720 b98fc34e4f1d8bc2372f99864bb8da6e 200 SUPERFAMILY SSF52980 32 195 2.95E-62 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 SPSF3K_RS07165 db6e6870472d0a5ecca575ff6324e8d8 62 Pfam PF10031 Small integral membrane protein (DUF2273) 3 49 3.5E-15 T 29-03-2018 IPR018730 Protein of unknown function DUF2273 SPSF3K_RS10580 0034deeea37eae9ee0c4ee5c0419fc36 162 SUPERFAMILY SSF52255 4 159 1.05E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SPSF3K_RS10580 0034deeea37eae9ee0c4ee5c0419fc36 162 Gene3D G3DSA:3.40.50.7700 1 162 4.0E-66 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SPSF3K_RS10580 0034deeea37eae9ee0c4ee5c0419fc36 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 32.362 T 29-03-2018 IPR033747 Class I PurE SPSF3K_RS10580 0034deeea37eae9ee0c4ee5c0419fc36 162 PIRSF PIRSF001338 1 162 6.1E-70 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 SPSF3K_RS10580 0034deeea37eae9ee0c4ee5c0419fc36 162 SMART SM01001 3 154 4.8E-100 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SPSF3K_RS10580 0034deeea37eae9ee0c4ee5c0419fc36 162 Pfam PF00731 AIR carboxylase 4 150 1.9E-64 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SPSF3K_RS10580 0034deeea37eae9ee0c4ee5c0419fc36 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 3.6E-66 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 SPSF3K_RS02225 a71470b7fbf6fba117d8a08a56173253 169 Gene3D G3DSA:1.10.3760.10 1 169 5.3E-60 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 SPSF3K_RS02225 a71470b7fbf6fba117d8a08a56173253 169 Pfam PF04608 Phosphatidylglycerophosphatase A 20 156 9.6E-22 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 SPSF3K_RS02225 a71470b7fbf6fba117d8a08a56173253 169 SUPERFAMILY SSF101307 6 158 4.45E-52 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 SPSF3K_RS02225 a71470b7fbf6fba117d8a08a56173253 169 PIRSF PIRSF019587 2 166 2.8E-75 T 29-03-2018 IPR026038 Putative phosphatidylglycerophosphatase SPSF3K_RS07695 adc4d45e9d75916c7d6d2236c6a32a25 306 SUPERFAMILY SSF53448 19 294 5.16E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS07695 adc4d45e9d75916c7d6d2236c6a32a25 306 Gene3D G3DSA:3.90.550.10 16 302 1.8E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS07695 adc4d45e9d75916c7d6d2236c6a32a25 306 Pfam PF00535 Glycosyl transferase family 2 19 156 1.7E-13 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SPSF3K_RS01335 bed5e24dc183394189c9c72268d31c0d 216 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 204 9.6E-58 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SPSF3K_RS01335 bed5e24dc183394189c9c72268d31c0d 216 Pfam PF01081 KDPG and KHG aldolase 9 199 5.8E-49 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SPSF3K_RS01335 bed5e24dc183394189c9c72268d31c0d 216 SUPERFAMILY SSF51569 2 207 1.08E-62 T 29-03-2018 SPSF3K_RS01335 bed5e24dc183394189c9c72268d31c0d 216 Gene3D G3DSA:3.20.20.70 4 213 6.4E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS00035 da6450f32fb41700fdb6b5e11214220e 859 Pfam PF09586 Bacterial membrane protein YfhO 16 839 4.7E-222 T 29-03-2018 IPR018580 Uncharacterised protein family YfhO SPSF3K_RS09740 597f02d7e74e2341d65054dfc944ff75 486 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 154 333 2.4E-9 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SPSF3K_RS09740 597f02d7e74e2341d65054dfc944ff75 486 PIRSF PIRSF000484 2 478 1.9E-150 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 SPSF3K_RS09740 597f02d7e74e2341d65054dfc944ff75 486 SUPERFAMILY SSF51690 137 476 3.53E-127 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 SPSF3K_RS09740 597f02d7e74e2341d65054dfc944ff75 486 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 8 463 7.1E-188 T 29-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 SPSF3K_RS09740 597f02d7e74e2341d65054dfc944ff75 486 SUPERFAMILY SSF54675 2 136 4.84E-47 T 29-03-2018 SPSF3K_RS09740 597f02d7e74e2341d65054dfc944ff75 486 Gene3D G3DSA:3.20.140.10 5 383 2.3E-125 T 29-03-2018 SPSF3K_RS05705 5cffa6005780026ef1747708e836fdd1 107 Pfam PF01022 Bacterial regulatory protein, arsR family 16 60 1.3E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS05705 5cffa6005780026ef1747708e836fdd1 107 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 31 49 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 SPSF3K_RS05705 5cffa6005780026ef1747708e836fdd1 107 SMART SM00418 8 88 3.4E-25 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS05705 5cffa6005780026ef1747708e836fdd1 107 Gene3D G3DSA:1.10.10.10 8 75 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05705 5cffa6005780026ef1747708e836fdd1 107 SUPERFAMILY SSF46785 1 89 9.58E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05705 5cffa6005780026ef1747708e836fdd1 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.8E-18 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS05705 5cffa6005780026ef1747708e836fdd1 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 1.8E-18 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS05705 5cffa6005780026ef1747708e836fdd1 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.8E-18 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS05705 5cffa6005780026ef1747708e836fdd1 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 40 1.8E-18 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPSF3K_RS01175 18d51732deedc12426cdd5b24046dfa8 70 Pfam PF13619 KTSC domain 8 45 1.1E-4 T 29-03-2018 IPR025309 KTSC domain SPSF3K_RS08405 eba691f98ad4784433aa543bfa7e3d52 132 Gene3D G3DSA:1.10.260.40 1 117 1.1E-16 T 29-03-2018 SPSF3K_RS08405 eba691f98ad4784433aa543bfa7e3d52 132 Pfam PF01381 Helix-turn-helix 10 64 2.2E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS08405 eba691f98ad4784433aa543bfa7e3d52 132 SUPERFAMILY SSF47413 3 66 1.23E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS08405 eba691f98ad4784433aa543bfa7e3d52 132 SMART SM00530 9 64 5.1E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS05090 30a3b72c08a5086980d116ec7af94524 163 Pfam PF17255 Family of unknown function (DUF5322) 5 137 1.0E-51 T 29-03-2018 IPR020215 Pore-forming protein, EbsA SPSF3K_RS05090 30a3b72c08a5086980d116ec7af94524 163 ProDom PD091538 PORE-FORMING FORMING PORE PEPTIDE EBSA PEPTIDE GBS1458 SMU.692 SAG1388 7 130 4.0E-44 T 29-03-2018 IPR020215 Pore-forming protein, EbsA SPSF3K_RS09270 6649dcddc6cf273bca1ffb9085e3879b 522 PRINTS PR00447 Natural resistance-associated macrophage protein signature 340 359 3.9E-45 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SPSF3K_RS09270 6649dcddc6cf273bca1ffb9085e3879b 522 PRINTS PR00447 Natural resistance-associated macrophage protein signature 225 248 3.9E-45 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SPSF3K_RS09270 6649dcddc6cf273bca1ffb9085e3879b 522 PRINTS PR00447 Natural resistance-associated macrophage protein signature 114 140 3.9E-45 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SPSF3K_RS09270 6649dcddc6cf273bca1ffb9085e3879b 522 PRINTS PR00447 Natural resistance-associated macrophage protein signature 368 385 3.9E-45 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SPSF3K_RS09270 6649dcddc6cf273bca1ffb9085e3879b 522 PRINTS PR00447 Natural resistance-associated macrophage protein signature 142 161 3.9E-45 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SPSF3K_RS09270 6649dcddc6cf273bca1ffb9085e3879b 522 Pfam PF01566 Natural resistance-associated macrophage protein 55 439 1.6E-112 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SPSF3K_RS09270 6649dcddc6cf273bca1ffb9085e3879b 522 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 33 429 1.0E-102 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 SPSF3K_RS05795 f1d97e920886a4b07648c71abde57536 205 Gene3D G3DSA:1.20.5.40 112 131 1.6E-9 T 29-03-2018 SPSF3K_RS05795 f1d97e920886a4b07648c71abde57536 205 Gene3D G3DSA:1.10.10.60 132 186 5.6E-7 T 29-03-2018 SPSF3K_RS05795 f1d97e920886a4b07648c71abde57536 205 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SPSF3K_RS05795 f1d97e920886a4b07648c71abde57536 205 Gene3D G3DSA:3.40.50.1390 2 111 4.9E-29 T 29-03-2018 SPSF3K_RS05795 f1d97e920886a4b07648c71abde57536 205 SUPERFAMILY SSF53041 1 141 2.35E-35 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS05795 f1d97e920886a4b07648c71abde57536 205 SMART SM00857 3 142 3.4E-40 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS05795 f1d97e920886a4b07648c71abde57536 205 ProSitePatterns PS00398 Site-specific recombinases signature 2. 54 66 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 SPSF3K_RS05795 f1d97e920886a4b07648c71abde57536 205 Pfam PF00239 Resolvase, N terminal domain 4 141 1.2E-33 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPSF3K_RS07450 f713c9865fcdbfb6ceff387247cc229a 130 Pfam PF11753 Protein of unknwon function (DUF3310) 5 65 1.3E-19 T 29-03-2018 IPR021739 SaV-like SPSF3K_RS04720 ea8fbdb112bf0f2cb1560fb82fd9509f 181 Gene3D G3DSA:3.30.70.1260 93 175 2.5E-11 T 29-03-2018 SPSF3K_RS04720 ea8fbdb112bf0f2cb1560fb82fd9509f 181 SUPERFAMILY SSF160379 3 175 3.79E-42 T 29-03-2018 SPSF3K_RS04720 ea8fbdb112bf0f2cb1560fb82fd9509f 181 Pfam PF08002 Protein of unknown function (DUF1697) 3 136 4.4E-30 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 SPSF3K_RS04720 ea8fbdb112bf0f2cb1560fb82fd9509f 181 Gene3D G3DSA:3.30.70.1280 2 84 5.0E-25 T 29-03-2018 SPSF3K_RS04720 ea8fbdb112bf0f2cb1560fb82fd9509f 181 PIRSF PIRSF008502 1 179 6.7E-28 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 SPSF3K_RS07385 16e31611476d61d2479e3621d37954c6 231 SUPERFAMILY SSF52096 4 177 9.45E-40 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SPSF3K_RS07385 16e31611476d61d2479e3621d37954c6 231 Pfam PF00574 Clp protease 37 173 3.6E-31 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SPSF3K_RS07385 16e31611476d61d2479e3621d37954c6 231 Gene3D G3DSA:3.90.226.10 4 186 5.3E-27 T 29-03-2018 SPSF3K_RS01180 6a845f25f66a5d799e12c56b33a96f63 270 Pfam PF00156 Phosphoribosyl transferase domain 107 263 3.5E-26 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPSF3K_RS01180 6a845f25f66a5d799e12c56b33a96f63 270 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 10 73 7.0E-28 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 SPSF3K_RS01180 6a845f25f66a5d799e12c56b33a96f63 270 SUPERFAMILY SSF46785 2 73 3.13E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01180 6a845f25f66a5d799e12c56b33a96f63 270 Gene3D G3DSA:3.40.50.2020 74 270 1.8E-30 T 29-03-2018 SPSF3K_RS01180 6a845f25f66a5d799e12c56b33a96f63 270 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 4.2E-28 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 SPSF3K_RS01180 6a845f25f66a5d799e12c56b33a96f63 270 Gene3D G3DSA:1.10.10.10 1 73 3.2E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS01180 6a845f25f66a5d799e12c56b33a96f63 270 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 269 2.1E-119 T 29-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 SPSF3K_RS01180 6a845f25f66a5d799e12c56b33a96f63 270 SUPERFAMILY SSF53271 85 236 4.97E-35 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS04955 e32ef777828ca8fa3ee90d3a8f159975 80 Gene3D G3DSA:3.40.1190.20 15 80 7.2E-6 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS04955 e32ef777828ca8fa3ee90d3a8f159975 80 SUPERFAMILY SSF53613 20 77 5.51E-9 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS04955 e32ef777828ca8fa3ee90d3a8f159975 80 Pfam PF00294 pfkB family carbohydrate kinase 23 69 3.9E-8 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SPSF3K_RS04415 bf4f5848318ca4b0a9393476a7f585c3 124 Pfam PF14478 Domain of unknown function (DUF4430) 56 121 3.1E-18 T 29-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 SPSF3K_RS05915 1120a6dd4a67a271277b546df4d88b79 226 Pfam PF13610 DDE domain 72 203 7.4E-41 T 29-03-2018 IPR032874 DDE domain SPSF3K_RS05915 1120a6dd4a67a271277b546df4d88b79 226 Gene3D G3DSA:3.30.420.10 60 200 1.7E-14 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS05915 1120a6dd4a67a271277b546df4d88b79 226 SUPERFAMILY SSF53098 69 184 1.8E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS07140 cf198e10781aad35addb777f5e6257c7 163 Pfam PF08534 Redoxin 17 154 1.1E-22 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SPSF3K_RS07140 cf198e10781aad35addb777f5e6257c7 163 Gene3D G3DSA:3.40.30.10 7 162 6.6E-24 T 29-03-2018 SPSF3K_RS07140 cf198e10781aad35addb777f5e6257c7 163 SUPERFAMILY SSF52833 2 156 5.04E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS07140 cf198e10781aad35addb777f5e6257c7 163 Hamap MF_00269 Probable thiol peroxidase [tpx]. 1 160 35.158 T 29-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 SPSF3K_RS07140 cf198e10781aad35addb777f5e6257c7 163 ProSitePatterns PS01265 Tpx family signature. 80 91 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 SPSF3K_RS03070 c37ce47b31f658114e285585669b3a01 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 72 5.7E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SPSF3K_RS03070 c37ce47b31f658114e285585669b3a01 308 SUPERFAMILY SSF161098 102 287 4.71E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS03070 c37ce47b31f658114e285585669b3a01 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 306 3.0E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS03070 c37ce47b31f658114e285585669b3a01 308 Gene3D G3DSA:1.10.3720.10 42 308 7.8E-27 T 29-03-2018 SPSF3K_RS08140 093fca06106b59f9603db7c35aca3db3 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.394 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 SPSF3K_RS08140 093fca06106b59f9603db7c35aca3db3 172 Gene3D G3DSA:3.40.50.2020 1 171 7.1E-40 T 29-03-2018 SPSF3K_RS08140 093fca06106b59f9603db7c35aca3db3 172 Pfam PF00156 Phosphoribosyl transferase domain 32 149 8.2E-15 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPSF3K_RS08140 093fca06106b59f9603db7c35aca3db3 172 SUPERFAMILY SSF53271 4 168 9.53E-50 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS08140 093fca06106b59f9603db7c35aca3db3 172 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 169 4.2E-66 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 SPSF3K_RS10440 9d58d52b5834cbd36999b316b53e58f3 118 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 118 5.7E-46 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10440 9d58d52b5834cbd36999b316b53e58f3 118 SUPERFAMILY SSF53137 7 116 8.94E-54 T 29-03-2018 SPSF3K_RS10440 9d58d52b5834cbd36999b316b53e58f3 118 Gene3D G3DSA:3.30.420.100 2 118 3.2E-42 T 29-03-2018 SPSF3K_RS10440 9d58d52b5834cbd36999b316b53e58f3 118 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 118 1.3E-49 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS10440 9d58d52b5834cbd36999b316b53e58f3 118 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 118 29.539 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01250 4ef0feaac58a50b8dd47e0f41918d1e1 311 SMART SM00382 38 231 1.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS01250 4ef0feaac58a50b8dd47e0f41918d1e1 311 SUPERFAMILY SSF52540 8 253 2.54E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01250 4ef0feaac58a50b8dd47e0f41918d1e1 311 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 266 5.1E-8 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SPSF3K_RS01250 4ef0feaac58a50b8dd47e0f41918d1e1 311 Gene3D G3DSA:3.40.50.300 5 309 4.8E-80 T 29-03-2018 SPSF3K_RS01250 4ef0feaac58a50b8dd47e0f41918d1e1 311 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS01250 4ef0feaac58a50b8dd47e0f41918d1e1 311 Pfam PF00005 ABC transporter 30 181 7.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08125 cf92c4f00047acdd84f15af4bcaf57e5 214 Pfam PF02517 CAAX protease self-immunity 121 210 1.5E-14 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 SPSF3K_RS10280 06b3345fc6ac071d63955394f10cf545 75 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 5 67 4.0E-21 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS10280 06b3345fc6ac071d63955394f10cf545 75 Gene3D G3DSA:1.10.260.40 1 75 1.3E-7 T 29-03-2018 SPSF3K_RS10280 06b3345fc6ac071d63955394f10cf545 75 SUPERFAMILY SSF47413 1 68 2.94E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS00180 dd662aba68ecf1d28e9986e3c0334f8c 72 Pfam PF14131 Domain of unknown function (DUF4298) 2 63 3.4E-9 T 29-03-2018 IPR025384 Protein of unknown function DUF4298 SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 Pfam PF16326 ABC transporter C-terminal domain 555 622 1.0E-11 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 SUPERFAMILY SSF52540 302 524 7.83E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 SMART SM00382 341 511 2.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 SMART SM00382 28 235 7.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 SUPERFAMILY SSF52540 5 238 8.12E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 Gene3D G3DSA:3.40.50.300 283 548 2.0E-49 T 29-03-2018 SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 Pfam PF00005 ABC transporter 20 184 6.1E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 Pfam PF00005 ABC transporter 333 466 6.6E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 Pfam PF12848 ABC transporter 223 292 2.2E-10 T 29-03-2018 IPR032781 ABC-transporter extension domain SPSF3K_RS05365 8d04ab5e5a8328720b3ca026fd4e61e3 625 Gene3D G3DSA:3.40.50.300 4 282 2.1E-51 T 29-03-2018 SPSF3K_RS00660 037f29b47930c81658f35b3d3e5d238a 155 PIRSF PIRSF010607 1 151 2.3E-61 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 SPSF3K_RS00660 037f29b47930c81658f35b3d3e5d238a 155 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 5 146 2.0E-47 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 SPSF3K_RS02105 ab535d098d4f8e390484b3af46ab9635 326 Gene3D G3DSA:1.10.10.60 1 51 7.3E-12 T 29-03-2018 SPSF3K_RS02105 ab535d098d4f8e390484b3af46ab9635 326 Pfam PF04198 Putative sugar-binding domain 60 314 1.5E-76 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 SPSF3K_RS02105 ab535d098d4f8e390484b3af46ab9635 326 Pfam PF13384 Homeodomain-like domain 1 49 1.3E-5 T 29-03-2018 SPSF3K_RS02105 ab535d098d4f8e390484b3af46ab9635 326 SUPERFAMILY SSF100950 60 314 4.95E-67 T 29-03-2018 SPSF3K_RS02105 ab535d098d4f8e390484b3af46ab9635 326 Gene3D G3DSA:3.40.50.1360 52 314 5.2E-40 T 29-03-2018 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 SUPERFAMILY SSF47413 6 64 1.61E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 Pfam PF13377 Periplasmic binding protein-like domain 179 332 8.3E-22 T 29-03-2018 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 TIGRFAM TIGR01481 ccpA: catabolite control protein A 5 333 3.4E-161 T 29-03-2018 IPR006377 Catabolite control protein A GO:0006355 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 2.0E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 Gene3D G3DSA:3.40.50.2300 180 315 2.1E-28 T 29-03-2018 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 29-03-2018 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 8.1E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 8.1E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 Gene3D G3DSA:3.40.50.2300 60 179 6.1E-29 T 29-03-2018 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 SMART SM00354 6 76 1.2E-37 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 Gene3D G3DSA:1.10.260.40 7 59 1.0E-24 T 29-03-2018 SPSF3K_RS04060 b42b4700a0810fb28c31e129c094b738 333 SUPERFAMILY SSF53822 66 333 3.53E-65 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS09700 85e79bcd780b332cdf8392dbb52ff648 386 SUPERFAMILY SSF53335 147 222 2.83E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS09700 85e79bcd780b332cdf8392dbb52ff648 386 SUPERFAMILY SSF53335 259 372 2.83E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS09700 85e79bcd780b332cdf8392dbb52ff648 386 Gene3D G3DSA:3.40.50.150 165 385 2.6E-31 T 29-03-2018 SPSF3K_RS09700 85e79bcd780b332cdf8392dbb52ff648 386 SMART SM00981 58 159 3.1E-9 T 29-03-2018 IPR004114 THUMP domain GO:0003723 SPSF3K_RS09700 85e79bcd780b332cdf8392dbb52ff648 386 Pfam PF01170 Putative RNA methylase family UPF0020 167 371 9.5E-56 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPSF3K_RS09700 85e79bcd780b332cdf8392dbb52ff648 386 Pfam PF02926 THUMP domain 29 158 7.3E-6 T 29-03-2018 IPR004114 THUMP domain GO:0003723 SPSF3K_RS08610 05583294bec3a93dccc26024c9dd7083 216 Gene3D G3DSA:3.40.50.1000 1 37 0.058 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08610 05583294bec3a93dccc26024c9dd7083 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 182 7.4E-20 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08610 05583294bec3a93dccc26024c9dd7083 216 SUPERFAMILY SSF56784 1 213 1.19E-33 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08610 05583294bec3a93dccc26024c9dd7083 216 Gene3D G3DSA:3.40.50.1000 64 216 6.8E-23 T 29-03-2018 IPR023214 HAD-like domain SPSF3K_RS08670 07f6d468824f210c64fd6b0685cabd29 727 Pfam PF00753 Metallo-beta-lactamase superfamily 472 678 4.9E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08670 07f6d468824f210c64fd6b0685cabd29 727 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 65 710 1.1E-81 T 29-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 SPSF3K_RS08670 07f6d468824f210c64fd6b0685cabd29 727 SMART SM00849 475 681 1.6E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08670 07f6d468824f210c64fd6b0685cabd29 727 Gene3D G3DSA:3.60.15.10 461 705 2.7E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08670 07f6d468824f210c64fd6b0685cabd29 727 SUPERFAMILY SSF56281 467 713 4.33E-48 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS08670 07f6d468824f210c64fd6b0685cabd29 727 Pfam PF03772 Competence protein 196 442 1.7E-27 T 29-03-2018 IPR004477 ComEC/Rec2-related protein SPSF3K_RS08280 9b48b42569db72ca4efdc35dc595c881 246 SUPERFAMILY SSF52540 6 238 7.1E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS08280 9b48b42569db72ca4efdc35dc595c881 246 Pfam PF00005 ABC transporter 21 169 6.9E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS08280 9b48b42569db72ca4efdc35dc595c881 246 Gene3D G3DSA:3.40.50.300 3 245 4.1E-75 T 29-03-2018 SPSF3K_RS08280 9b48b42569db72ca4efdc35dc595c881 246 PIRSF PIRSF039085 2 245 2.3E-113 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SPSF3K_RS08280 9b48b42569db72ca4efdc35dc595c881 246 SMART SM00382 30 238 6.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS08280 9b48b42569db72ca4efdc35dc595c881 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS04975 2eec17ef09b8ff67753ea49b391b1e38 314 Pfam PF04228 Putative neutral zinc metallopeptidase 1 307 6.0E-123 T 29-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative SPSF3K_RS04975 2eec17ef09b8ff67753ea49b391b1e38 314 Gene3D G3DSA:3.40.390.10 80 207 3.6E-4 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SPSF3K_RS08925 1793843b7024851231861fd1f23a5de7 382 Pfam PF08478 POTRA domain, FtsQ-type 124 195 2.8E-11 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type SPSF3K_RS08925 1793843b7024851231861fd1f23a5de7 382 Hamap MF_00912 Cell division protein DivIB [divIB]. 26 333 28.501 T 29-03-2018 IPR026580 Cell division protein DivIB SPSF3K_RS08925 1793843b7024851231861fd1f23a5de7 382 Pfam PF03799 Cell division protein FtsQ 199 312 1.7E-8 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB SPSF3K_RS03495 d9dce28d83fd55f3cb39bdee0e3d0093 61 Gene3D G3DSA:1.10.260.40 2 58 1.2E-7 T 29-03-2018 SPSF3K_RS03495 d9dce28d83fd55f3cb39bdee0e3d0093 61 SUPERFAMILY SSF47413 3 56 1.77E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS03495 d9dce28d83fd55f3cb39bdee0e3d0093 61 Pfam PF01381 Helix-turn-helix 14 47 3.6E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS03375 ad09e15756eee3629f61b41db04bd7eb 181 Gene3D G3DSA:3.40.1280.10 15 181 2.2E-36 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPSF3K_RS03375 ad09e15756eee3629f61b41db04bd7eb 181 Pfam PF00588 SpoU rRNA Methylase family 18 158 8.9E-33 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SPSF3K_RS03375 ad09e15756eee3629f61b41db04bd7eb 181 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 17 167 34.078 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 SPSF3K_RS03375 ad09e15756eee3629f61b41db04bd7eb 181 PIRSF PIRSF029256 16 170 1.6E-59 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 SPSF3K_RS03375 ad09e15756eee3629f61b41db04bd7eb 181 SUPERFAMILY SSF75217 13 180 3.34E-39 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases SPSF3K_RS04920 c4e3498f462e83c6469c5dd955ba8982 78 Pfam PF06612 Protein of unknown function (DUF1146) 14 64 1.7E-15 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 SPSF3K_RS04920 c4e3498f462e83c6469c5dd955ba8982 78 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 10 77 1.3E-23 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 SPSF3K_RS07380 0144db47640d200da8185550fa520102 395 Gene3D G3DSA:3.30.2320.10 232 344 1.0E-21 T 29-03-2018 SPSF3K_RS07380 0144db47640d200da8185550fa520102 395 Pfam PF05065 Phage capsid family 115 377 8.2E-32 T 29-03-2018 IPR024455 Phage capsid SPSF3K_RS07380 0144db47640d200da8185550fa520102 395 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 6 376 1.9E-66 T 29-03-2018 IPR024455 Phage capsid SPSF3K_RS07380 0144db47640d200da8185550fa520102 395 SUPERFAMILY SSF56563 110 381 2.09E-39 T 29-03-2018 SPSF3K_RS04995 f53207a6b5756a5bd907986bc346f1da 270 SMART SM00079 39 260 0.0012 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 SPSF3K_RS04995 f53207a6b5756a5bd907986bc346f1da 270 Gene3D G3DSA:3.40.190.10 30 142 1.5E-34 T 29-03-2018 SPSF3K_RS04995 f53207a6b5756a5bd907986bc346f1da 270 Gene3D G3DSA:3.40.190.10 143 223 1.3E-16 T 29-03-2018 SPSF3K_RS04995 f53207a6b5756a5bd907986bc346f1da 270 SUPERFAMILY SSF53850 6 259 2.89E-61 T 29-03-2018 SPSF3K_RS04995 f53207a6b5756a5bd907986bc346f1da 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 258 2.6E-53 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS04995 f53207a6b5756a5bd907986bc346f1da 270 SMART SM00062 39 261 9.7E-52 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPSF3K_RS03980 5d7a2168447c2ab6a95866e288246221 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.1E-5 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SPSF3K_RS03980 5d7a2168447c2ab6a95866e288246221 78 PRINTS PR01651 Protein-export SecG membrane protein signature 56 78 3.1E-5 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SPSF3K_RS03980 5d7a2168447c2ab6a95866e288246221 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 76 4.7E-18 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SPSF3K_RS03980 5d7a2168447c2ab6a95866e288246221 78 Pfam PF03840 Preprotein translocase SecG subunit 4 74 5.1E-15 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SPSF3K_RS01695 84243164a95aafb44a444c4d9c49a8ad 293 Gene3D G3DSA:3.30.420.40 2 136 2.0E-22 T 29-03-2018 SPSF3K_RS01695 84243164a95aafb44a444c4d9c49a8ad 293 Gene3D G3DSA:3.30.420.40 137 262 4.7E-19 T 29-03-2018 SPSF3K_RS01695 84243164a95aafb44a444c4d9c49a8ad 293 ProSitePatterns PS01125 ROK family signature. 131 156 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SPSF3K_RS01695 84243164a95aafb44a444c4d9c49a8ad 293 Pfam PF00480 ROK family 5 288 6.2E-73 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SPSF3K_RS01695 84243164a95aafb44a444c4d9c49a8ad 293 SUPERFAMILY SSF53067 5 290 3.13E-42 T 29-03-2018 SPSF3K_RS11045 d0248a8d2c37a22f988c6dc5b1df172c 121 Pfam PF05713 Bacterial mobilisation protein (MobC) 66 120 5.3E-6 T 29-03-2018 IPR008687 Bacterial mobilisation SPSF3K_RS10965 d0248a8d2c37a22f988c6dc5b1df172c 121 Pfam PF05713 Bacterial mobilisation protein (MobC) 66 120 5.3E-6 T 29-03-2018 IPR008687 Bacterial mobilisation SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 289 304 9.0E-30 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 308 320 9.0E-30 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 254 264 9.0E-30 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 9.0E-30 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 126 141 9.0E-30 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 Gene3D G3DSA:1.10.390.10 275 442 6.4E-54 T 29-03-2018 SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 Pfam PF11838 ERAP1-like C-terminal domain 513 824 1.2E-39 T 29-03-2018 IPR024571 ERAP1-like C-terminal domain SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 SUPERFAMILY SSF55486 201 449 1.9E-79 T 29-03-2018 SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 Pfam PF01433 Peptidase family M1 domain 203 438 5.5E-87 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 SUPERFAMILY SSF63737 10 192 8.24E-46 T 29-03-2018 SPSF3K_RS07050 de1722b674a1b2906ec260253e6c8784 845 Gene3D G3DSA:2.60.40.1730 1 192 2.2E-42 T 29-03-2018 SPSF3K_RS10245 0f5d02562c9ca83373f417f98d904098 359 Pfam PF00535 Glycosyl transferase family 2 5 170 6.9E-12 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SPSF3K_RS10245 0f5d02562c9ca83373f417f98d904098 359 SUPERFAMILY SSF53448 2 263 3.45E-20 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS10245 0f5d02562c9ca83373f417f98d904098 359 Pfam PF04138 GtrA-like protein 228 345 2.3E-8 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SPSF3K_RS10245 0f5d02562c9ca83373f417f98d904098 359 Gene3D G3DSA:3.90.550.10 3 221 7.7E-16 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS10265 d603e1361758f24cab0a15a189b4f2bc 237 Gene3D G3DSA:3.20.20.450 1 236 7.5E-21 T 29-03-2018 IPR001633 EAL domain SPSF3K_RS10265 d603e1361758f24cab0a15a189b4f2bc 237 Pfam PF00563 EAL domain 4 225 4.8E-16 T 29-03-2018 IPR001633 EAL domain SPSF3K_RS10265 d603e1361758f24cab0a15a189b4f2bc 237 SUPERFAMILY SSF141868 4 225 3.14E-21 T 29-03-2018 IPR001633 EAL domain SPSF3K_RS00760 f9acde252c0d5af1a5c240f8d888d740 221 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 211 4.9E-26 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS00760 f9acde252c0d5af1a5c240f8d888d740 221 SMART SM00934 7 212 2.9E-29 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 SPSF3K_RS00760 f9acde252c0d5af1a5c240f8d888d740 221 SUPERFAMILY SSF51366 5 220 2.59E-36 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SPSF3K_RS00760 f9acde252c0d5af1a5c240f8d888d740 221 Gene3D G3DSA:3.20.20.70 4 221 2.0E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS01470 397f6821b4cf2fdc41038ef176d39e67 545 Pfam PF01293 Phosphoenolpyruvate carboxykinase 76 485 2.6E-17 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 SPSF3K_RS01470 397f6821b4cf2fdc41038ef176d39e67 545 SUPERFAMILY SSF53795 233 522 5.1E-59 T 29-03-2018 SPSF3K_RS01470 397f6821b4cf2fdc41038ef176d39e67 545 Gene3D G3DSA:3.90.228.20 328 526 4.3E-32 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SPSF3K_RS01470 397f6821b4cf2fdc41038ef176d39e67 545 Gene3D G3DSA:3.90.228.20 234 327 1.9E-12 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SPSF3K_RS01470 397f6821b4cf2fdc41038ef176d39e67 545 SUPERFAMILY SSF68923 62 231 2.96E-28 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SPSF3K_RS01470 397f6821b4cf2fdc41038ef176d39e67 545 Gene3D G3DSA:3.40.449.10 67 231 1.4E-30 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 Pfam PF04270 Streptococcal histidine triad protein 114 132 0.37 T 29-03-2018 IPR006270 Streptococcal histidine triad repeat SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 Pfam PF04270 Streptococcal histidine triad protein 74 92 0.002 T 29-03-2018 IPR006270 Streptococcal histidine triad repeat SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 Pfam PF04270 Streptococcal histidine triad protein 203 252 3.6E-24 T 29-03-2018 IPR006270 Streptococcal histidine triad repeat SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 Pfam PF04270 Streptococcal histidine triad protein 351 399 6.1E-18 T 29-03-2018 IPR006270 Streptococcal histidine triad repeat SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 Pfam PF04270 Streptococcal histidine triad protein 548 565 0.71 T 29-03-2018 IPR006270 Streptococcal histidine triad repeat SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 Pfam PF04270 Streptococcal histidine triad protein 461 507 8.9E-12 T 29-03-2018 IPR006270 Streptococcal histidine triad repeat SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 TIGRFAM TIGR01363 strep_his_triad: streptococcal histidine triad protein 2 394 5.7E-134 T 29-03-2018 IPR023832 Histidine triad protein SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 SUPERFAMILY SSF142887 458 508 3.01E-14 T 29-03-2018 SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 SUPERFAMILY SSF142887 347 398 4.84E-14 T 29-03-2018 SPSF3K_RS06440 51dcff2db571b63f32a346a055810c98 816 SUPERFAMILY SSF142887 200 251 1.1E-18 T 29-03-2018 SPSF3K_RS02690 d66c7ffe662051e315e367f7b3a97583 384 SUPERFAMILY SSF56349 72 367 5.59E-61 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPSF3K_RS02690 d66c7ffe662051e315e367f7b3a97583 384 Pfam PF00589 Phage integrase family 175 366 1.3E-24 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS02690 d66c7ffe662051e315e367f7b3a97583 384 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 72 125 9.0E-15 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPSF3K_RS02690 d66c7ffe662051e315e367f7b3a97583 384 Gene3D G3DSA:1.10.150.130 65 174 5.5E-18 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SPSF3K_RS02690 d66c7ffe662051e315e367f7b3a97583 384 Gene3D G3DSA:1.10.443.10 175 369 2.2E-36 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS02690 d66c7ffe662051e315e367f7b3a97583 384 Pfam PF14657 Arm DNA-binding domain 17 51 1.7E-6 T 29-03-2018 IPR028259 AP2-like integrase, N-terminal domain SPSF3K_RS00470 ac25ff9b114eb3af832223101380c8a7 183 Pfam PF03352 Methyladenine glycosylase 7 182 3.1E-75 T 29-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 SPSF3K_RS00470 ac25ff9b114eb3af832223101380c8a7 183 SUPERFAMILY SSF48150 1 182 2.12E-75 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 SPSF3K_RS00470 ac25ff9b114eb3af832223101380c8a7 183 Gene3D G3DSA:1.10.340.30 1 183 1.8E-79 T 29-03-2018 SPSF3K_RS09460 57dc2e580dca0c7b13f83888232a4ac4 394 Pfam PF12698 ABC-2 family transporter protein 18 385 1.4E-44 T 29-03-2018 SPSF3K_RS09460 57dc2e580dca0c7b13f83888232a4ac4 394 Gene3D G3DSA:3.40.1710.10 38 214 4.8E-7 T 29-03-2018 SPSF3K_RS07200 f6774209668d2dbb5fab087932df0182 443 PRINTS PR00175 Sodium/alanine symporter signature 86 108 2.4E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPSF3K_RS07200 f6774209668d2dbb5fab087932df0182 443 PRINTS PR00175 Sodium/alanine symporter signature 180 198 2.4E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPSF3K_RS07200 f6774209668d2dbb5fab087932df0182 443 PRINTS PR00175 Sodium/alanine symporter signature 303 321 2.4E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPSF3K_RS07200 f6774209668d2dbb5fab087932df0182 443 PRINTS PR00175 Sodium/alanine symporter signature 208 227 2.4E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPSF3K_RS07200 f6774209668d2dbb5fab087932df0182 443 PRINTS PR00175 Sodium/alanine symporter signature 347 369 2.4E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPSF3K_RS07200 f6774209668d2dbb5fab087932df0182 443 PRINTS PR00175 Sodium/alanine symporter signature 406 426 2.4E-55 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPSF3K_RS07200 f6774209668d2dbb5fab087932df0182 443 Pfam PF01235 Sodium:alanine symporter family 49 441 2.4E-148 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPSF3K_RS07200 f6774209668d2dbb5fab087932df0182 443 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 437 6.0E-160 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPSF3K_RS07200 f6774209668d2dbb5fab087932df0182 443 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPSF3K_RS04265 d6737b56418785c7b2448687a30ba975 259 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 130 142 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SPSF3K_RS04265 d6737b56418785c7b2448687a30ba975 259 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 252 17.302 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SPSF3K_RS04265 d6737b56418785c7b2448687a30ba975 259 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 246 1.7E-67 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SPSF3K_RS04265 d6737b56418785c7b2448687a30ba975 259 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 4 246 9.4E-75 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 SPSF3K_RS09200 fd8b7dc2323c7af89a7a892fb7050c1c 84 Gene3D G3DSA:1.20.58.90 1 84 1.2E-46 T 29-03-2018 SPSF3K_RS09200 fd8b7dc2323c7af89a7a892fb7050c1c 84 Pfam PF08930 Domain of unknown function (DUF1912) 1 84 8.6E-47 T 29-03-2018 IPR015026 Protein of unknown function DUF1912 SPSF3K_RS09200 fd8b7dc2323c7af89a7a892fb7050c1c 84 SUPERFAMILY SSF140121 1 77 1.02E-39 T 29-03-2018 SPSF3K_RS09155 84321d32c83816e1430b576e8644c469 319 SUPERFAMILY SSF53098 160 309 3.04E-21 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS09155 84321d32c83816e1430b576e8644c469 319 Pfam PF00665 Integrase core domain 167 265 7.8E-10 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 SPSF3K_RS09155 84321d32c83816e1430b576e8644c469 319 Gene3D G3DSA:3.30.420.10 155 317 4.8E-22 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS09155 84321d32c83816e1430b576e8644c469 319 Gene3D G3DSA:1.10.10.60 6 68 1.1E-4 T 29-03-2018 SPSF3K_RS04935 a6a6f4cdcd94bb1ea0bfe1cfa6c18259 289 Pfam PF01223 DNA/RNA non-specific endonuclease 92 247 3.8E-16 T 29-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SPSF3K_RS04935 a6a6f4cdcd94bb1ea0bfe1cfa6c18259 289 SMART SM00892 111 287 2.6E-23 T 29-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SPSF3K_RS09975 1ff9be9ac693dcf20b9c5284418260f8 263 Gene3D G3DSA:3.90.1200.10 44 261 8.1E-21 T 29-03-2018 SPSF3K_RS09975 1ff9be9ac693dcf20b9c5284418260f8 263 Pfam PF01636 Phosphotransferase enzyme family 41 212 2.2E-15 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase SPSF3K_RS09975 1ff9be9ac693dcf20b9c5284418260f8 263 SUPERFAMILY SSF56112 14 220 3.55E-32 T 29-03-2018 IPR011009 Protein kinase-like domain SPSF3K_RS09900 2d07daf9ca0a788b994513033c8bbf0c 225 Gene3D G3DSA:1.20.190.10 26 162 5.8E-4 T 29-03-2018 SPSF3K_RS10555 89b05b7e2e80822eb91bbb1770555b67 142 Gene3D G3DSA:3.40.50.2300 1 142 9.7E-41 T 29-03-2018 SPSF3K_RS10555 89b05b7e2e80822eb91bbb1770555b67 142 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 3.5E-12 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SPSF3K_RS10555 89b05b7e2e80822eb91bbb1770555b67 142 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 78 93 3.5E-12 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SPSF3K_RS10555 89b05b7e2e80822eb91bbb1770555b67 142 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 113 128 3.5E-12 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SPSF3K_RS10555 89b05b7e2e80822eb91bbb1770555b67 142 SUPERFAMILY SSF52788 1 140 1.7E-42 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SPSF3K_RS10555 89b05b7e2e80822eb91bbb1770555b67 142 SMART SM00226 2 139 5.3E-32 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SPSF3K_RS10555 89b05b7e2e80822eb91bbb1770555b67 142 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 137 1.6E-30 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily SPSF3K_RS01435 3a891422f9659419b44dfae63773be58 130 Gene3D G3DSA:2.40.50.100 58 130 1.8E-20 T 29-03-2018 SPSF3K_RS01435 3a891422f9659419b44dfae63773be58 130 Pfam PF00364 Biotin-requiring enzyme 64 129 9.4E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment SPSF3K_RS01435 3a891422f9659419b44dfae63773be58 130 SUPERFAMILY SSF51230 55 129 1.3E-23 T 29-03-2018 IPR011053 Single hybrid motif SPSF3K_RS01435 3a891422f9659419b44dfae63773be58 130 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 86 103 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 SPSF3K_RS03125 a154c047bd0a1762c6aa223b72cebc25 372 Gene3D G3DSA:3.40.50.300 59 227 3.3E-30 T 29-03-2018 SPSF3K_RS03125 a154c047bd0a1762c6aa223b72cebc25 372 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 372 4.2E-151 T 29-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH SPSF3K_RS03125 a154c047bd0a1762c6aa223b72cebc25 372 SUPERFAMILY SSF52540 65 281 5.54E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS03125 a154c047bd0a1762c6aa223b72cebc25 372 Pfam PF01926 50S ribosome-binding GTPase 166 227 4.2E-13 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 SPSF3K_RS06680 8abf70d07d5b04141e90810bd0697418 334 Pfam PF13602 Zinc-binding dehydrogenase 187 330 3.6E-18 T 29-03-2018 SPSF3K_RS06680 8abf70d07d5b04141e90810bd0697418 334 SUPERFAMILY SSF50129 1 152 4.41E-34 T 29-03-2018 IPR011032 GroES-like SPSF3K_RS06680 8abf70d07d5b04141e90810bd0697418 334 Gene3D G3DSA:3.90.180.10 251 334 0.0027 T 29-03-2018 SPSF3K_RS06680 8abf70d07d5b04141e90810bd0697418 334 Gene3D G3DSA:3.90.180.10 1 147 5.0E-43 T 29-03-2018 SPSF3K_RS06680 8abf70d07d5b04141e90810bd0697418 334 SUPERFAMILY SSF51735 118 251 7.13E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS06680 8abf70d07d5b04141e90810bd0697418 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 91 6.1E-12 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SPSF3K_RS06680 8abf70d07d5b04141e90810bd0697418 334 Gene3D G3DSA:3.40.50.720 148 248 1.9E-14 T 29-03-2018 SPSF3K_RS06680 8abf70d07d5b04141e90810bd0697418 334 SMART SM00829 11 330 2.2E-11 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SPSF3K_RS04565 9d05840f3ecbdd8e8557bd8da96423b0 303 SUPERFAMILY SSF55608 117 218 1.53E-13 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 SPSF3K_RS04565 9d05840f3ecbdd8e8557bd8da96423b0 303 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 301 2.8E-103 T 29-03-2018 IPR033981 Sporulation regulator WhiA-like SPSF3K_RS04565 9d05840f3ecbdd8e8557bd8da96423b0 303 Pfam PF02650 WhiA C-terminal HTH domain 217 300 1.1E-28 T 29-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal SPSF3K_RS04565 9d05840f3ecbdd8e8557bd8da96423b0 303 Gene3D G3DSA:3.10.28.10 15 98 1.8E-8 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 SPSF3K_RS04565 9d05840f3ecbdd8e8557bd8da96423b0 303 Pfam PF14527 WhiA LAGLIDADG-like domain 122 214 6.2E-28 T 29-03-2018 SPSF3K_RS04565 9d05840f3ecbdd8e8557bd8da96423b0 303 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 303 28.616 T 29-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 SPSF3K_RS04565 9d05840f3ecbdd8e8557bd8da96423b0 303 Gene3D G3DSA:3.10.28.10 121 200 2.6E-11 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 SPSF3K_RS04565 9d05840f3ecbdd8e8557bd8da96423b0 303 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 17 99 9.5E-28 T 29-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain SPSF3K_RS06875 2a2bf038b49741d52de1a3550cbbe618 257 Pfam PF01351 Ribonuclease HII 74 252 8.9E-37 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain SPSF3K_RS06875 2a2bf038b49741d52de1a3550cbbe618 257 Hamap MF_00052_B Ribonuclease HII [rnhB]. 72 253 34.202 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 SPSF3K_RS06875 2a2bf038b49741d52de1a3550cbbe618 257 SUPERFAMILY SSF53098 61 257 1.82E-66 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS06875 2a2bf038b49741d52de1a3550cbbe618 257 Gene3D G3DSA:3.30.420.10 48 257 4.9E-69 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS01370 ae29d78bf1e4e072a39e7b7b80cf1128 73 SUPERFAMILY SSF47413 3 69 3.75E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS01370 ae29d78bf1e4e072a39e7b7b80cf1128 73 SMART SM00530 7 63 5.4E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS01370 ae29d78bf1e4e072a39e7b7b80cf1128 73 Gene3D G3DSA:1.10.260.40 2 73 7.6E-13 T 29-03-2018 SPSF3K_RS01370 ae29d78bf1e4e072a39e7b7b80cf1128 73 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 68 3.8E-22 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS08555 ba67cb5171b2949b9c9ba0f6a3a9e5c7 321 Pfam PF00268 Ribonucleotide reductase, small chain 8 278 2.3E-85 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08555 ba67cb5171b2949b9c9ba0f6a3a9e5c7 321 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 5 317 7.0E-149 T 29-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPSF3K_RS08555 ba67cb5171b2949b9c9ba0f6a3a9e5c7 321 PIRSF PIRSF000355 1 314 9.2E-72 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 SPSF3K_RS08555 ba67cb5171b2949b9c9ba0f6a3a9e5c7 321 Gene3D G3DSA:1.10.620.20 4 291 2.3E-75 T 29-03-2018 SPSF3K_RS08555 ba67cb5171b2949b9c9ba0f6a3a9e5c7 321 SUPERFAMILY SSF47240 3 317 6.57E-99 T 29-03-2018 IPR009078 Ferritin-like superfamily SPSF3K_RS09235 5b387534de28c293dc6f4b41f093bb35 295 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 73 1.5E-7 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPSF3K_RS09235 5b387534de28c293dc6f4b41f093bb35 295 Pfam PF00589 Phage integrase family 120 277 6.0E-40 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS09235 5b387534de28c293dc6f4b41f093bb35 295 Gene3D G3DSA:1.10.443.10 107 285 6.0E-44 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS09235 5b387534de28c293dc6f4b41f093bb35 295 Gene3D G3DSA:1.10.150.130 2 99 3.0E-16 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SPSF3K_RS09235 5b387534de28c293dc6f4b41f093bb35 295 SUPERFAMILY SSF56349 9 283 1.24E-50 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPSF3K_RS00355 55fe041dd2087181d94984f92fd74f1c 204 Pfam PF03596 Cadmium resistance transporter 12 201 2.9E-73 T 29-03-2018 IPR004676 Cadmium resistance transporter SPSF3K_RS00355 55fe041dd2087181d94984f92fd74f1c 204 TIGRFAM TIGR00779 cad: cadmium resistance transporter family protein 12 198 1.5E-57 T 29-03-2018 IPR004676 Cadmium resistance transporter SPSF3K_RS06265 53d4e319134f0c7b593298f4e1b2ba05 190 Pfam PF01928 CYTH domain 4 182 1.1E-34 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 SPSF3K_RS06265 53d4e319134f0c7b593298f4e1b2ba05 190 PIRSF PIRSF012526 1 190 8.0E-73 T 29-03-2018 IPR009195 Uncharacterised protein family YjbK SPSF3K_RS06265 53d4e319134f0c7b593298f4e1b2ba05 190 SMART SM01118 3 189 4.5E-20 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 SPSF3K_RS06265 53d4e319134f0c7b593298f4e1b2ba05 190 Gene3D G3DSA:2.40.320.10 4 187 1.0E-33 T 29-03-2018 SPSF3K_RS06265 53d4e319134f0c7b593298f4e1b2ba05 190 SUPERFAMILY SSF55154 3 184 2.45E-29 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 SPSF3K_RS09595 1b1872a04d3246c06a7f4e9429f42522 222 SUPERFAMILY SSF53271 76 221 5.25E-18 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like SPSF3K_RS09595 1b1872a04d3246c06a7f4e9429f42522 222 Pfam PF00156 Phosphoribosyl transferase domain 135 220 1.4E-6 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPSF3K_RS09595 1b1872a04d3246c06a7f4e9429f42522 222 Gene3D G3DSA:3.40.50.2020 53 222 9.2E-17 T 29-03-2018 SPSF3K_RS09835 53b41bd276427a611e7acb10dc466c77 487 Pfam PF05043 Mga helix-turn-helix domain 79 160 9.9E-21 T 29-03-2018 IPR007737 Mga helix-turn-helix domain SPSF3K_RS09835 53b41bd276427a611e7acb10dc466c77 487 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 14 57 1.1E-7 T 29-03-2018 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain SPSF3K_RS09835 53b41bd276427a611e7acb10dc466c77 487 Gene3D G3DSA:1.10.10.10 1 66 0.013 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS09835 53b41bd276427a611e7acb10dc466c77 487 Gene3D G3DSA:1.10.10.10 94 156 1.5E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS05260 9988077dc14102d9332280cc6a42f5b9 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.8E-35 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05260 9988077dc14102d9332280cc6a42f5b9 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.423 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05260 9988077dc14102d9332280cc6a42f5b9 90 Pfam PF00886 Ribosomal protein S16 9 67 8.2E-26 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05260 9988077dc14102d9332280cc6a42f5b9 90 SUPERFAMILY SSF54565 2 86 1.57E-34 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS05260 9988077dc14102d9332280cc6a42f5b9 90 Gene3D G3DSA:3.30.1320.10 2 85 3.0E-35 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS04050 03c17c0383425ad0933d12ad34361500 84 SUPERFAMILY SSF46689 2 61 5.64E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS00965 97eca147d9e27362b63ecc46f8ad939d 147 Pfam PF00692 dUTPase 18 145 2.2E-15 T 29-03-2018 IPR029054 dUTPase-like SPSF3K_RS00965 97eca147d9e27362b63ecc46f8ad939d 147 Gene3D G3DSA:2.70.40.10 6 147 2.0E-34 T 29-03-2018 SPSF3K_RS00965 97eca147d9e27362b63ecc46f8ad939d 147 SUPERFAMILY SSF51283 11 147 3.53E-35 T 29-03-2018 IPR029054 dUTPase-like SPSF3K_RS01840 01ec0b9820b7ba7e5c60b5aab9e45079 185 Pfam PF06042 Nucleotidyltransferase 20 180 1.0E-50 T 29-03-2018 IPR009267 Putative nucleotidyltransferase SPSF3K_RS05845 c6e0d6bee17be9551a1ff501b9b06df8 244 Pfam PF08241 Methyltransferase domain 47 141 4.2E-25 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SPSF3K_RS05845 c6e0d6bee17be9551a1ff501b9b06df8 244 Gene3D G3DSA:3.40.50.150 26 242 4.4E-41 T 29-03-2018 SPSF3K_RS05845 c6e0d6bee17be9551a1ff501b9b06df8 244 SUPERFAMILY SSF53335 4 242 8.96E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS08745 7488f410849e6f8dfa80fc1cfebd9897 256 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 75 84 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site SPSF3K_RS08745 7488f410849e6f8dfa80fc1cfebd9897 256 Gene3D G3DSA:1.20.1080.10 2 256 2.7E-75 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS08745 7488f410849e6f8dfa80fc1cfebd9897 256 Pfam PF01226 Formate/nitrite transporter 8 248 5.3E-69 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 296 302 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 SUPERFAMILY SSF53335 5 42 4.33E-129 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 SUPERFAMILY SSF53335 86 507 4.33E-129 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 220 234 8.1E-22 T 29-03-2018 SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 192 208 8.1E-22 T 29-03-2018 SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 329 353 8.1E-22 T 29-03-2018 SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 293 305 8.1E-22 T 29-03-2018 SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 Gene3D G3DSA:3.40.50.150 190 470 3.4E-71 T 29-03-2018 SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 4 492 4.2E-122 T 29-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 Pfam PF02384 N-6 DNA Methylase 169 476 1.6E-104 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SPSF3K_RS05620 1eae7a121e355ad15b900e110e647d6d 531 Pfam PF12161 HsdM N-terminal domain 5 157 8.5E-23 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain SPSF3K_RS07310 5868a6465cb38e2af5bd5403bef2aff5 258 SMART SM00644 9 149 3.1E-22 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SPSF3K_RS07310 5868a6465cb38e2af5bd5403bef2aff5 258 Gene3D G3DSA:3.40.80.10 3 184 1.5E-19 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SPSF3K_RS07310 5868a6465cb38e2af5bd5403bef2aff5 258 SUPERFAMILY SSF55846 18 167 1.65E-21 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SPSF3K_RS07310 5868a6465cb38e2af5bd5403bef2aff5 258 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 21 149 1.8E-6 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 SPSF3K_RS07605 8f088a62c2c72ced7a42a2224c5e5e11 214 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 7 203 19.307 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 SPSF3K_RS07605 8f088a62c2c72ced7a42a2224c5e5e11 214 Pfam PF02660 Glycerol-3-phosphate acyltransferase 11 194 2.1E-50 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 SPSF3K_RS07605 8f088a62c2c72ced7a42a2224c5e5e11 214 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 2 202 2.4E-53 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 SPSF3K_RS07605 8f088a62c2c72ced7a42a2224c5e5e11 214 SMART SM01207 10 195 3.6E-79 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 SPSF3K_RS06130 aa019056344f7bb38b7695c3ad5adadc 258 Gene3D G3DSA:1.10.3720.10 4 251 1.5E-36 T 29-03-2018 SPSF3K_RS06130 aa019056344f7bb38b7695c3ad5adadc 258 SUPERFAMILY SSF161098 5 249 6.41E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS06130 aa019056344f7bb38b7695c3ad5adadc 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 243 1.4E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS07045 182f44c8a2521a2f8a41e79df4e204a6 224 SMART SM00448 2 112 1.2E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS07045 182f44c8a2521a2f8a41e79df4e204a6 224 Pfam PF00072 Response regulator receiver domain 4 112 5.4E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS07045 182f44c8a2521a2f8a41e79df4e204a6 224 Gene3D G3DSA:1.10.10.10 125 224 6.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07045 182f44c8a2521a2f8a41e79df4e204a6 224 SMART SM00862 145 220 5.3E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS07045 182f44c8a2521a2f8a41e79df4e204a6 224 Gene3D G3DSA:3.40.50.2300 1 124 5.3E-29 T 29-03-2018 SPSF3K_RS07045 182f44c8a2521a2f8a41e79df4e204a6 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 2.2E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPSF3K_RS07045 182f44c8a2521a2f8a41e79df4e204a6 224 SUPERFAMILY SSF52172 1 176 1.04E-35 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS00535 9258c149db9c65557c25aa4a320a5ed8 284 SUPERFAMILY SSF54593 2 159 1.41E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS00535 9258c149db9c65557c25aa4a320a5ed8 284 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 121 9.3E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPSF3K_RS00535 9258c149db9c65557c25aa4a320a5ed8 284 Gene3D G3DSA:3.10.180.10 4 156 1.2E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS00535 9258c149db9c65557c25aa4a320a5ed8 284 SUPERFAMILY SSF54593 165 263 2.09E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS00535 9258c149db9c65557c25aa4a320a5ed8 284 Gene3D G3DSA:3.10.180.10 164 283 2.0E-8 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 9 95 1.2E-37 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 Gene3D G3DSA:3.90.226.10 2 250 2.9E-60 T 29-03-2018 SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 7 254 2.5E-103 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 SUPERFAMILY SSF52096 6 254 9.11E-79 T 29-03-2018 IPR029045 ClpP/crotonase-like domain SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 100 113 1.2E-41 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 35 46 1.2E-41 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 60 78 1.2E-41 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 129 1.2E-41 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 144 153 1.2E-41 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS10060 80b846cf05e38e34a3fc4fd71c075f33 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 81 97 1.2E-41 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 SPSF3K_RS05975 14366352366a58a04af0355e005ba708 327 Hamap MF_00734 Tagatose 1,6-diphosphate aldolase [lacD]. 1 327 209.053 T 29-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 SPSF3K_RS05975 14366352366a58a04af0355e005ba708 327 SMART SM01133 22 284 3.3E-28 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SPSF3K_RS05975 14366352366a58a04af0355e005ba708 327 SUPERFAMILY SSF51569 9 323 9.16E-70 T 29-03-2018 SPSF3K_RS05975 14366352366a58a04af0355e005ba708 327 Pfam PF01791 DeoC/LacD family aldolase 22 283 2.2E-78 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SPSF3K_RS05975 14366352366a58a04af0355e005ba708 327 Gene3D G3DSA:3.20.20.70 6 327 2.0E-78 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS05975 14366352366a58a04af0355e005ba708 327 TIGRFAM TIGR01232 lacD: tagatose 1,6-diphosphate aldolase 5 326 4.8E-182 T 29-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 SPSF3K_RS06105 32655fde1b2d6761968f72931da46174 119 SMART SM00905 4 117 9.3E-46 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SPSF3K_RS06105 32655fde1b2d6761968f72931da46174 119 Pfam PF02152 Dihydroneopterin aldolase 4 116 4.1E-31 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SPSF3K_RS06105 32655fde1b2d6761968f72931da46174 119 SUPERFAMILY SSF55620 2 119 6.67E-38 T 29-03-2018 SPSF3K_RS06105 32655fde1b2d6761968f72931da46174 119 Gene3D G3DSA:3.30.1130.10 1 119 7.0E-33 T 29-03-2018 SPSF3K_RS06105 32655fde1b2d6761968f72931da46174 119 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 4.1E-30 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SPSF3K_RS06105 32655fde1b2d6761968f72931da46174 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 3.5E-39 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 SPSF3K_RS02265 27b8bd354139a5492fa6cd37c63a73f0 300 SUPERFAMILY SSF103481 220 296 1.44E-11 T 29-03-2018 SPSF3K_RS02265 27b8bd354139a5492fa6cd37c63a73f0 300 Pfam PF00892 EamA-like transporter family 11 144 1.8E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SPSF3K_RS02265 27b8bd354139a5492fa6cd37c63a73f0 300 Pfam PF00892 EamA-like transporter family 156 296 2.3E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 SPSF3K_RS02265 27b8bd354139a5492fa6cd37c63a73f0 300 SUPERFAMILY SSF103481 45 144 8.89E-13 T 29-03-2018 SPSF3K_RS02970 685df0c6fd86251056828ca052e1d3d4 121 Gene3D G3DSA:2.40.50.140 39 119 0.0013 T 29-03-2018 SPSF3K_RS02970 685df0c6fd86251056828ca052e1d3d4 121 Pfam PF03780 Asp23 family, cell envelope-related function 10 116 5.7E-31 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 SPSF3K_RS08840 a52b7ad50bebcf44694cc90545d5b354 44 Pfam PF12669 Virus attachment protein p12 family 3 35 2.7E-6 T 29-03-2018 SPSF3K_RS06670 a37014be83374f4f1544fe0cf75c1536 235 SUPERFAMILY SSF51261 82 232 7.85E-52 T 29-03-2018 IPR011055 Duplicated hybrid motif SPSF3K_RS06670 a37014be83374f4f1544fe0cf75c1536 235 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 151 163 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS06670 a37014be83374f4f1544fe0cf75c1536 235 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 89 209 1.2E-43 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS06670 a37014be83374f4f1544fe0cf75c1536 235 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 89 212 6.4E-49 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 SPSF3K_RS06670 a37014be83374f4f1544fe0cf75c1536 235 Gene3D G3DSA:2.70.70.10 78 235 5.3E-57 T 29-03-2018 SPSF3K_RS01550 690fcf57ff184e60387c761f7ae51150 303 Gene3D G3DSA:3.40.710.10 1 303 5.2E-50 T 29-03-2018 SPSF3K_RS01550 690fcf57ff184e60387c761f7ae51150 303 SUPERFAMILY SSF56601 2 291 1.29E-60 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS01550 690fcf57ff184e60387c761f7ae51150 303 Pfam PF00144 Beta-lactamase 2 292 2.2E-47 T 29-03-2018 IPR001466 Beta-lactamase-related SPSF3K_RS06480 3ef97888d3798f99cbfed93c578376a7 441 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 16 431 5.6E-93 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS06480 3ef97888d3798f99cbfed93c578376a7 441 Pfam PF02378 Phosphotransferase system, EIIC 30 359 1.7E-43 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS06480 3ef97888d3798f99cbfed93c578376a7 441 PIRSF PIRSF006351 4 439 2.0E-116 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 SPSF3K_RS03370 a69ca668883b043acff557ee4b51695e 79 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 67 3.0E-19 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SPSF3K_RS03370 a69ca668883b043acff557ee4b51695e 79 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 71 5.9E-27 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SPSF3K_RS03370 a69ca668883b043acff557ee4b51695e 79 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 68 23.217 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SPSF3K_RS03370 a69ca668883b043acff557ee4b51695e 79 SMART SM01234 1 67 1.3E-40 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SPSF3K_RS03370 a69ca668883b043acff557ee4b51695e 79 Pfam PF01809 Haemolytic domain 2 67 2.3E-26 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor SPSF3K_RS04420 02912ee12d51a60006272e5b226f73eb 596 Pfam PF01432 Peptidase family M3 199 574 5.4E-36 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 SPSF3K_RS04420 02912ee12d51a60006272e5b226f73eb 596 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 6 590 6.4E-186 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 SPSF3K_RS04420 02912ee12d51a60006272e5b226f73eb 596 Pfam PF08439 Oligopeptidase F 120 176 4.2E-5 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain SPSF3K_RS04420 02912ee12d51a60006272e5b226f73eb 596 Gene3D G3DSA:1.10.1370.10 80 563 3.8E-27 T 29-03-2018 SPSF3K_RS04420 02912ee12d51a60006272e5b226f73eb 596 SUPERFAMILY SSF55486 7 576 6.96E-85 T 29-03-2018 SPSF3K_RS10460 91f529da66c8f3fd88503cf7690e0a2a 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.554 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10460 91f529da66c8f3fd88503cf7690e0a2a 180 Gene3D G3DSA:3.30.1440.10 2 180 4.6E-78 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10460 91f529da66c8f3fd88503cf7690e0a2a 180 Pfam PF00673 ribosomal L5P family C-terminus 86 178 1.8E-39 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10460 91f529da66c8f3fd88503cf7690e0a2a 180 Pfam PF00281 Ribosomal protein L5 26 81 6.5E-26 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10460 91f529da66c8f3fd88503cf7690e0a2a 180 PIRSF PIRSF002161 1 180 3.8E-66 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10460 91f529da66c8f3fd88503cf7690e0a2a 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS10460 91f529da66c8f3fd88503cf7690e0a2a 180 SUPERFAMILY SSF55282 4 179 3.06E-75 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS00580 3aa2767ec5d7f4f0a62455bf9d78564f 306 SUPERFAMILY SSF52518 4 168 1.02E-35 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SPSF3K_RS00580 3aa2767ec5d7f4f0a62455bf9d78564f 306 SMART SM00861 6 172 2.5E-20 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SPSF3K_RS00580 3aa2767ec5d7f4f0a62455bf9d78564f 306 Gene3D G3DSA:3.40.50.920 182 306 3.5E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPSF3K_RS00580 3aa2767ec5d7f4f0a62455bf9d78564f 306 Pfam PF02780 Transketolase, C-terminal domain 184 299 2.6E-26 T 29-03-2018 IPR033248 Transketolase, C-terminal domain SPSF3K_RS00580 3aa2767ec5d7f4f0a62455bf9d78564f 306 Gene3D G3DSA:3.40.50.970 1 181 3.5E-29 T 29-03-2018 SPSF3K_RS00580 3aa2767ec5d7f4f0a62455bf9d78564f 306 SUPERFAMILY SSF52922 183 305 4.19E-29 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPSF3K_RS00580 3aa2767ec5d7f4f0a62455bf9d78564f 306 Pfam PF02779 Transketolase, pyrimidine binding domain 7 166 4.4E-20 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain SPSF3K_RS08815 0ccfdf9d2e12fb392df17ebed7f7ef5f 289 SUPERFAMILY SSF48576 3 269 1.22E-72 T 29-03-2018 IPR008949 Isoprenoid synthase domain SPSF3K_RS08815 0ccfdf9d2e12fb392df17ebed7f7ef5f 289 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 75 91 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SPSF3K_RS08815 0ccfdf9d2e12fb392df17ebed7f7ef5f 289 Pfam PF00348 Polyprenyl synthetase 26 254 1.4E-51 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 SPSF3K_RS08815 0ccfdf9d2e12fb392df17ebed7f7ef5f 289 Gene3D G3DSA:1.10.600.10 1 289 1.2E-69 T 29-03-2018 IPR008949 Isoprenoid synthase domain SPSF3K_RS08815 0ccfdf9d2e12fb392df17ebed7f7ef5f 289 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 205 217 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site SPSF3K_RS03740 7ecd66e41e75c692e64cfbbc19f506e0 239 Pfam PF06912 Protein of unknown function (DUF1275) 18 209 4.3E-31 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 SPSF3K_RS05335 78ca0463cf9832182f735fa77b3aebd8 267 Gene3D G3DSA:1.10.530.10 42 192 9.3E-34 T 29-03-2018 SPSF3K_RS05335 78ca0463cf9832182f735fa77b3aebd8 267 SMART SM00047 38 192 6.6E-46 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPSF3K_RS05335 78ca0463cf9832182f735fa77b3aebd8 267 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 55 187 3.7E-18 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPSF3K_RS02635 57cfde5ae3709e6b83316ba18dc9063f 251 Pfam PF07179 SseB protein N-terminal domain 149 245 1.7E-5 T 29-03-2018 IPR009839 SseB protein N-terminal domain SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 Pfam PF07729 FCD domain 93 204 4.4E-11 T 29-03-2018 IPR011711 GntR, C-terminal SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 4.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 4.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 SMART SM00345 9 68 9.5E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 SUPERFAMILY SSF46785 4 72 3.17E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 SUPERFAMILY SSF48008 92 207 1.49E-9 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 Gene3D G3DSA:1.10.10.10 2 70 1.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 Gene3D G3DSA:1.20.120.530 77 208 1.5E-11 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 SMART SM00895 93 209 1.4E-6 T 29-03-2018 IPR011711 GntR, C-terminal SPSF3K_RS08475 eee1ab761300b020d2b69f5268495eb3 215 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 68 4.2E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS07900 ab11852818f95fd6b7a842f61fef6480 386 SUPERFAMILY SSF53474 86 212 4.79E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS07900 ab11852818f95fd6b7a842f61fef6480 386 Gene3D G3DSA:3.40.50.1820 40 299 5.3E-14 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS07900 ab11852818f95fd6b7a842f61fef6480 386 Pfam PF11187 Protein of unknown function (DUF2974) 84 309 5.3E-68 T 29-03-2018 IPR024499 Protein of unknown function DUF2974 SPSF3K_RS00570 ef6f2dc327b4b4855a9d116571fae037 446 Pfam PF03611 PTS system sugar-specific permease component 7 402 6.6E-146 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 SPSF3K_RS03245 a5902109b41c602724fb4863a12b9daf 164 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 2 146 5.7E-58 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SPSF3K_RS03245 a5902109b41c602724fb4863a12b9daf 164 Pfam PF03477 ATP cone domain 50 136 5.5E-18 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 SPSF3K_RS03245 a5902109b41c602724fb4863a12b9daf 164 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 154 80.92 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SPSF3K_RS05030 683d4c4f6d7cc17517a9ba4c71297687 384 Gene3D G3DSA:3.40.50.2000 71 384 6.0E-11 T 29-03-2018 SPSF3K_RS05030 683d4c4f6d7cc17517a9ba4c71297687 384 SUPERFAMILY SSF53756 5 380 3.01E-22 T 29-03-2018 SPSF3K_RS05030 683d4c4f6d7cc17517a9ba4c71297687 384 Pfam PF09314 Domain of unknown function (DUF1972) 1 185 2.0E-93 T 29-03-2018 IPR015393 Domain of unknown function DUF1972 SPSF3K_RS05045 846d5f6bbe166092226fd1bdc3c74985 405 SMART SM00382 58 256 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05045 846d5f6bbe166092226fd1bdc3c74985 405 Pfam PF00005 ABC transporter 49 180 9.0E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS05045 846d5f6bbe166092226fd1bdc3c74985 405 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS05045 846d5f6bbe166092226fd1bdc3c74985 405 Gene3D G3DSA:3.40.50.300 6 276 4.3E-49 T 29-03-2018 SPSF3K_RS05045 846d5f6bbe166092226fd1bdc3c74985 405 SUPERFAMILY SSF52540 39 245 2.88E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01600 1ae16b6d25ed7cb388afda0c93b99827 181 Pfam PF02674 Colicin V production protein 2 164 7.3E-23 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 SPSF3K_RS04715 2d9ec9d2c41f9383a2778dce36a2122e 143 SUPERFAMILY SSF54593 2 136 2.28E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS04715 2d9ec9d2c41f9383a2778dce36a2122e 143 Gene3D G3DSA:3.10.180.10 1 143 2.1E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS04715 2d9ec9d2c41f9383a2778dce36a2122e 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 127 4.5E-12 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPSF3K_RS00120 b08fc9656cf380444fa2c53a92dcf489 223 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 5 200 1.5E-69 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SPSF3K_RS00120 b08fc9656cf380444fa2c53a92dcf489 223 Pfam PF03315 Serine dehydratase beta chain 8 135 5.6E-14 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SPSF3K_RS00120 b08fc9656cf380444fa2c53a92dcf489 223 Pfam PF01842 ACT domain 152 214 5.7E-9 T 29-03-2018 IPR002912 ACT domain SPSF3K_RS00120 b08fc9656cf380444fa2c53a92dcf489 223 PIRSF PIRSF036692 4 223 1.5E-104 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 SPSF3K_RS00120 b08fc9656cf380444fa2c53a92dcf489 223 Gene3D G3DSA:3.30.1330.90 16 140 6.2E-25 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SPSF3K_RS00120 b08fc9656cf380444fa2c53a92dcf489 223 SUPERFAMILY SSF143548 22 141 5.75E-30 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 SPSF3K_RS00120 b08fc9656cf380444fa2c53a92dcf489 223 Gene3D G3DSA:3.30.70.260 143 222 9.1E-15 T 29-03-2018 SPSF3K_RS00120 b08fc9656cf380444fa2c53a92dcf489 223 SUPERFAMILY SSF55021 140 220 8.4E-19 T 29-03-2018 SPSF3K_RS00975 7590d38fe2bd0d725f551890ed7742fe 165 Pfam PF00484 Carbonic anhydrase 32 159 7.7E-14 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPSF3K_RS00975 7590d38fe2bd0d725f551890ed7742fe 165 SUPERFAMILY SSF53056 4 163 4.06E-40 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPSF3K_RS00975 7590d38fe2bd0d725f551890ed7742fe 165 Gene3D G3DSA:3.40.1050.10 1 164 1.1E-38 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPSF3K_RS00975 7590d38fe2bd0d725f551890ed7742fe 165 SMART SM00947 24 164 1.2E-30 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPSF3K_RS09645 2d6fbffa8fce7ed58572c48ecb6b9fdc 246 SUPERFAMILY SSF81606 2 239 1.03E-59 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SPSF3K_RS09645 2d6fbffa8fce7ed58572c48ecb6b9fdc 246 Pfam PF13672 Protein phosphatase 2C 12 217 1.6E-16 T 29-03-2018 SPSF3K_RS09645 2d6fbffa8fce7ed58572c48ecb6b9fdc 246 SMART SM00332 1 238 9.7E-16 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SPSF3K_RS09645 2d6fbffa8fce7ed58572c48ecb6b9fdc 246 SMART SM00331 7 240 1.5E-33 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SPSF3K_RS09645 2d6fbffa8fce7ed58572c48ecb6b9fdc 246 Gene3D G3DSA:3.60.40.10 1 245 1.7E-40 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 SPSF3K_RS02965 1b470f1c44bb3cd2a40ed60fb690aeba 64 Gene3D G3DSA:1.10.1470.10 1 64 4.6E-19 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS02965 1b470f1c44bb3cd2a40ed60fb690aeba 64 SUPERFAMILY SSF69047 1 62 1.96E-15 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS02965 1b470f1c44bb3cd2a40ed60fb690aeba 64 Pfam PF05532 CsbD-like 4 55 1.4E-17 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS07640 f8d603992f61cb0a16c635d24d393804 127 Pfam PF07166 Protein of unknown function (DUF1398) 16 123 1.1E-22 T 29-03-2018 IPR009833 Uncharacterised protein DUF1398 SPSF3K_RS07640 f8d603992f61cb0a16c635d24d393804 127 Gene3D G3DSA:3.30.1810.10 3 123 4.9E-27 T 29-03-2018 IPR009833 Uncharacterised protein DUF1398 SPSF3K_RS07640 f8d603992f61cb0a16c635d24d393804 127 ProDom PD021249 YDFO YCGX ENVELOPE CYTOPLASMIC STY1988 CP-933X ECS1626 YBCV PROPHAGE 79 125 1.0E-5 T 29-03-2018 IPR009833 Uncharacterised protein DUF1398 SPSF3K_RS07640 f8d603992f61cb0a16c635d24d393804 127 SUPERFAMILY SSF160419 8 126 5.62E-33 T 29-03-2018 IPR009833 Uncharacterised protein DUF1398 SPSF3K_RS09075 9b6f4f27ba5fbacb4f424580e7b0438c 144 SUPERFAMILY SSF55729 10 142 1.58E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS09075 9b6f4f27ba5fbacb4f424580e7b0438c 144 Gene3D G3DSA:3.40.630.30 4 144 2.6E-25 T 29-03-2018 SPSF3K_RS09075 9b6f4f27ba5fbacb4f424580e7b0438c 144 Pfam PF13673 Acetyltransferase (GNAT) domain 32 142 6.3E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS08400 da40215138e9fd8e31c5c1c065fb45ab 125 Pfam PF08570 Protein of unknown function (DUF1761) 7 121 8.0E-25 T 29-03-2018 IPR013879 Protein of unknown function DUF1761 SPSF3K_RS04390 502596d57e4dc7e19a4ef51697052253 121 Pfam PF03733 Inner membrane component domain 66 115 1.1E-18 T 29-03-2018 IPR005185 Inner membrane component domain SPSF3K_RS04390 502596d57e4dc7e19a4ef51697052253 121 Pfam PF03733 Inner membrane component domain 4 54 1.2E-15 T 29-03-2018 IPR005185 Inner membrane component domain SPSF3K_RS04390 502596d57e4dc7e19a4ef51697052253 121 PIRSF PIRSF028777 1 121 2.5E-42 T 29-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 SPSF3K_RS07630 4a2e1096f8d100178c0bcc672c4807a5 482 Pfam PF01425 Amidase 22 468 6.3E-68 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPSF3K_RS07630 4a2e1096f8d100178c0bcc672c4807a5 482 Gene3D G3DSA:3.90.1300.10 1 480 2.3E-101 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPSF3K_RS07630 4a2e1096f8d100178c0bcc672c4807a5 482 SUPERFAMILY SSF75304 421 476 2.49E-102 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPSF3K_RS07630 4a2e1096f8d100178c0bcc672c4807a5 482 SUPERFAMILY SSF75304 4 388 2.49E-102 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPSF3K_RS01595 155398e14fd3bb3f04c01e36a139a284 102 Pfam PF05164 Cell division protein ZapA 12 93 2.4E-4 T 29-03-2018 IPR007838 Cell division protein ZapA-like SPSF3K_RS01595 155398e14fd3bb3f04c01e36a139a284 102 SUPERFAMILY SSF102829 11 90 3.4E-6 T 29-03-2018 IPR007838 Cell division protein ZapA-like SPSF3K_RS01585 87cea89b209eb1d196df446eea08132f 197 SUPERFAMILY SSF51306 22 196 1.83E-47 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SPSF3K_RS01585 87cea89b209eb1d196df446eea08132f 197 Pfam PF00717 Peptidase S24-like 30 97 6.3E-18 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C SPSF3K_RS01585 87cea89b209eb1d196df446eea08132f 197 Gene3D G3DSA:2.10.109.10 21 196 5.6E-36 T 29-03-2018 SPSF3K_RS01585 87cea89b209eb1d196df446eea08132f 197 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 4.6E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPSF3K_RS01585 87cea89b209eb1d196df446eea08132f 197 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 150 169 4.6E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPSF3K_RS01585 87cea89b209eb1d196df446eea08132f 197 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 73 85 4.6E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPSF3K_RS01585 87cea89b209eb1d196df446eea08132f 197 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 SPSF3K_RS01585 87cea89b209eb1d196df446eea08132f 197 ProSitePatterns PS00760 Signal peptidases I lysine active site. 75 87 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 SPSF3K_RS01585 87cea89b209eb1d196df446eea08132f 197 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 191 3.3E-42 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPSF3K_RS05425 705b6e966bec0f70f8d11bcfd20fd713 427 SUPERFAMILY SSF56542 225 424 1.16E-97 T 29-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SPSF3K_RS05425 705b6e966bec0f70f8d11bcfd20fd713 427 SUPERFAMILY SSF56542 8 120 1.16E-97 T 29-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SPSF3K_RS05425 705b6e966bec0f70f8d11bcfd20fd713 427 Gene3D G3DSA:3.90.770.10 212 387 3.0E-32 T 29-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SPSF3K_RS05425 705b6e966bec0f70f8d11bcfd20fd713 427 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 16 383 1.2E-104 T 29-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SPSF3K_RS05425 705b6e966bec0f70f8d11bcfd20fd713 427 Gene3D G3DSA:3.90.770.10 5 125 5.7E-21 T 29-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SPSF3K_RS05425 705b6e966bec0f70f8d11bcfd20fd713 427 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 9 383 6.2E-98 T 29-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 SPSF3K_RS05425 705b6e966bec0f70f8d11bcfd20fd713 427 SUPERFAMILY SSF55035 113 216 1.83E-31 T 29-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SPSF3K_RS05425 705b6e966bec0f70f8d11bcfd20fd713 427 Gene3D G3DSA:3.30.70.420 126 211 1.4E-29 T 29-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 SPSF3K_RS09950 c13dc350ba19e8461186be47215ea037 98 Pfam PF04296 Protein of unknown function (DUF448) 10 83 6.4E-23 T 29-03-2018 IPR007393 Domain of unknown function DUF448 SPSF3K_RS09950 c13dc350ba19e8461186be47215ea037 98 Gene3D G3DSA:3.30.1230.10 1 98 1.5E-28 T 29-03-2018 IPR007393 Domain of unknown function DUF448 SPSF3K_RS09950 c13dc350ba19e8461186be47215ea037 98 SUPERFAMILY SSF64376 5 96 1.05E-27 T 29-03-2018 IPR007393 Domain of unknown function DUF448 SPSF3K_RS09240 ad2d498bf80e2fea02ed910cc83c4153 392 SUPERFAMILY SSF103473 20 388 6.93E-27 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS09240 ad2d498bf80e2fea02ed910cc83c4153 392 Gene3D G3DSA:1.20.1250.20 2 195 1.5E-8 T 29-03-2018 SPSF3K_RS09240 ad2d498bf80e2fea02ed910cc83c4153 392 Gene3D G3DSA:1.20.1250.20 196 389 2.6E-16 T 29-03-2018 SPSF3K_RS01900 a5f7d7fea11dfd1eccdf1b8ea0af76f5 232 SUPERFAMILY SSF52540 3 214 2.08E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS01900 a5f7d7fea11dfd1eccdf1b8ea0af76f5 232 Gene3D G3DSA:3.40.50.300 2 226 1.0E-52 T 29-03-2018 SPSF3K_RS01900 a5f7d7fea11dfd1eccdf1b8ea0af76f5 232 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS01900 a5f7d7fea11dfd1eccdf1b8ea0af76f5 232 SMART SM00382 28 215 1.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS01900 a5f7d7fea11dfd1eccdf1b8ea0af76f5 232 Pfam PF00005 ABC transporter 19 165 2.1E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00810 dae135b2e5d3022c2d8bd0f818362f36 156 Pfam PF01475 Ferric uptake regulator family 23 142 2.5E-35 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SPSF3K_RS00810 dae135b2e5d3022c2d8bd0f818362f36 156 Gene3D G3DSA:1.10.10.10 1 96 4.2E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00810 dae135b2e5d3022c2d8bd0f818362f36 156 SUPERFAMILY SSF46785 15 147 5.78E-37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 3.8E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 403 3.8E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 439 451 3.8E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 3.8E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 3.8E-17 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 Pfam PF00232 Glycosyl hydrolase family 1 3 474 2.0E-130 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 SUPERFAMILY SSF51445 2 470 4.11E-166 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 Gene3D G3DSA:3.20.20.80 1 477 1.3E-155 T 29-03-2018 SPSF3K_RS04010 912e4244fecad6da30d256832ce7b4da 477 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site SPSF3K_RS02790 ae251c2986a86a08c0324d00aa37ceb6 904 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 14 50 7.4E-10 T 29-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPSF3K_RS02790 ae251c2986a86a08c0324d00aa37ceb6 904 Pfam PF04650 YSIRK type signal peptide 17 39 6.9E-5 T 29-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPSF3K_RS02790 ae251c2986a86a08c0324d00aa37ceb6 904 Gene3D G3DSA:3.40.710.10 701 889 2.5E-4 T 29-03-2018 SPSF3K_RS02790 ae251c2986a86a08c0324d00aa37ceb6 904 Pfam PF08481 GBS Bsp-like repeat 280 362 3.5E-24 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS02790 ae251c2986a86a08c0324d00aa37ceb6 904 Pfam PF08481 GBS Bsp-like repeat 394 455 2.4E-12 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS02790 ae251c2986a86a08c0324d00aa37ceb6 904 Pfam PF08481 GBS Bsp-like repeat 204 265 7.0E-13 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS02790 ae251c2986a86a08c0324d00aa37ceb6 904 Pfam PF08481 GBS Bsp-like repeat 571 657 4.8E-23 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS02790 ae251c2986a86a08c0324d00aa37ceb6 904 Pfam PF08481 GBS Bsp-like repeat 469 549 5.6E-22 T 29-03-2018 IPR013688 GBS Bsp-like SPSF3K_RS02790 ae251c2986a86a08c0324d00aa37ceb6 904 SUPERFAMILY SSF56601 697 885 2.04E-13 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS06525 2598702a0726a400d60931d9cd8b50ff 104 Pfam PF06125 Bacterial protein of unknown function (DUF961) 4 102 3.1E-36 T 29-03-2018 IPR010365 Protein of unknown function DUF961 SPSF3K_RS01170 9948cd7606fe347d3220cc493a4e433e 312 Gene3D G3DSA:1.10.3210.10 140 305 1.7E-13 T 29-03-2018 SPSF3K_RS01170 9948cd7606fe347d3220cc493a4e433e 312 SUPERFAMILY SSF109604 144 281 9.42E-12 T 29-03-2018 SPSF3K_RS01170 9948cd7606fe347d3220cc493a4e433e 312 Gene3D G3DSA:2.40.50.140 1 95 6.6E-9 T 29-03-2018 SPSF3K_RS01170 9948cd7606fe347d3220cc493a4e433e 312 Pfam PF01966 HD domain 160 278 5.7E-8 T 29-03-2018 IPR006674 HD domain SPSF3K_RS04655 d1e67c7ac6e95812d981157297360951 339 SUPERFAMILY SSF51556 8 334 2.16E-75 T 29-03-2018 IPR032466 Metal-dependent hydrolase SPSF3K_RS04655 d1e67c7ac6e95812d981157297360951 339 Hamap MF_00540 Adenosine deaminase [add]. 4 332 51.463 T 29-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 SPSF3K_RS04655 d1e67c7ac6e95812d981157297360951 339 Pfam PF00962 Adenosine/AMP deaminase 9 329 2.0E-57 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 SPSF3K_RS04655 d1e67c7ac6e95812d981157297360951 339 Gene3D G3DSA:3.20.20.140 2 337 3.6E-75 T 29-03-2018 SPSF3K_RS04655 d1e67c7ac6e95812d981157297360951 339 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 331 6.5E-84 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 SPSF3K_RS07340 0a8616af2bb8fb8804c43659a4d78ece 511 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 5 129 2.3E-12 T 29-03-2018 IPR006520 Streptococcus phage 7201, Orf34, N-terminal SPSF3K_RS07340 0a8616af2bb8fb8804c43659a4d78ece 511 Pfam PF05709 Phage tail protein 35 511 1.5E-29 T 29-03-2018 IPR008841 Siphovirus-type tail component SPSF3K_RS07180 c2940747ff30276587dafaa7b9b3b338 81 Pfam PF04226 Transglycosylase associated protein 33 77 1.7E-11 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SPSF3K_RS07185 c2940747ff30276587dafaa7b9b3b338 81 Pfam PF04226 Transglycosylase associated protein 33 77 1.7E-11 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SPSF3K_RS08905 81a976f2f81e48fb441300327d868f44 219 Pfam PF04472 Cell division protein SepF 128 196 3.6E-18 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 SPSF3K_RS08905 81a976f2f81e48fb441300327d868f44 219 Hamap MF_01197 Cell division protein SepF [sepF]. 4 204 19.393 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 Gene3D G3DSA:1.20.1080.10 1 233 2.2E-78 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 PRINTS PR00783 Major intrinsic protein family signature 80 99 8.6E-45 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 PRINTS PR00783 Major intrinsic protein family signature 165 187 8.6E-45 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 PRINTS PR00783 Major intrinsic protein family signature 43 67 8.6E-45 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 PRINTS PR00783 Major intrinsic protein family signature 1 19 8.6E-45 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 PRINTS PR00783 Major intrinsic protein family signature 212 232 8.6E-45 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 PRINTS PR00783 Major intrinsic protein family signature 135 153 8.6E-45 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 SUPERFAMILY SSF81338 3 231 2.49E-68 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 Pfam PF00230 Major intrinsic protein 3 229 4.4E-43 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 TIGRFAM TIGR00861 MIP: MIP family channel proteins 5 229 3.4E-53 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS09845 034acb51871f9ca8e58118a08b296e96 233 ProSitePatterns PS00221 MIP family signature. 61 69 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 SPSF3K_RS07540 6d458789e3ec034913ccf182a6c1028d 132 Pfam PF01381 Helix-turn-helix 32 73 5.7E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS07540 6d458789e3ec034913ccf182a6c1028d 132 SUPERFAMILY SSF47413 5 79 5.93E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS07540 6d458789e3ec034913ccf182a6c1028d 132 Gene3D G3DSA:1.10.260.40 1 132 1.3E-12 T 29-03-2018 SPSF3K_RS04285 1de3499b44dda369872af0aaad081230 308 Gene3D G3DSA:3.20.20.60 1 93 1.1E-4 T 29-03-2018 SPSF3K_RS04285 1de3499b44dda369872af0aaad081230 308 Pfam PF01136 Peptidase family U32 74 303 2.8E-38 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 Gene3D G3DSA:3.40.190.10 181 265 1.7E-12 T 29-03-2018 SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 Gene3D G3DSA:1.10.10.10 1 91 1.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 Gene3D G3DSA:3.40.190.10 92 180 1.3E-12 T 29-03-2018 SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 SUPERFAMILY SSF46785 1 87 3.06E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 Pfam PF03466 LysR substrate binding domain 87 292 1.5E-21 T 29-03-2018 IPR005119 LysR, substrate-binding SPSF3K_RS06855 ce32849b1b71f94582b81a0316a7bc5b 294 SUPERFAMILY SSF53850 89 292 1.67E-24 T 29-03-2018 SPSF3K_RS09385 7fe767da01cdcfd0e0313b7164186246 225 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 112 3.3E-16 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SPSF3K_RS09385 7fe767da01cdcfd0e0313b7164186246 225 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 209 5.4E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 SPSF3K_RS09385 7fe767da01cdcfd0e0313b7164186246 225 Gene3D G3DSA:2.40.110.10 119 225 1.2E-28 T 29-03-2018 SPSF3K_RS09385 7fe767da01cdcfd0e0313b7164186246 225 SUPERFAMILY SSF56645 10 220 4.19E-55 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 SPSF3K_RS09385 7fe767da01cdcfd0e0313b7164186246 225 Gene3D G3DSA:1.10.540.10 3 114 6.0E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 SPSF3K_RS04635 809667fe78e377ee5b50ef5ff5d5a5fa 86 Pfam PF01197 Ribosomal protein L31 1 78 2.6E-28 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS04635 809667fe78e377ee5b50ef5ff5d5a5fa 86 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 27.412 T 29-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS04635 809667fe78e377ee5b50ef5ff5d5a5fa 86 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS04635 809667fe78e377ee5b50ef5ff5d5a5fa 86 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.2E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS04635 809667fe78e377ee5b50ef5ff5d5a5fa 86 PRINTS PR01249 Ribosomal protein L31 signature 59 77 5.2E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS04635 809667fe78e377ee5b50ef5ff5d5a5fa 86 PRINTS PR01249 Ribosomal protein L31 signature 44 59 5.2E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS04635 809667fe78e377ee5b50ef5ff5d5a5fa 86 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 2.8E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS04635 809667fe78e377ee5b50ef5ff5d5a5fa 86 SUPERFAMILY SSF143800 1 79 9.42E-24 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00890 d867cde44aa608cf3e5ec611c3b43fac 232 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 8 231 2.2E-105 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 SPSF3K_RS00890 d867cde44aa608cf3e5ec611c3b43fac 232 SUPERFAMILY SSF51161 84 218 1.66E-47 T 29-03-2018 IPR011004 Trimeric LpxA-like SPSF3K_RS00890 d867cde44aa608cf3e5ec611c3b43fac 232 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 SPSF3K_RS00890 d867cde44aa608cf3e5ec611c3b43fac 232 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 170 198 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 SPSF3K_RS00890 d867cde44aa608cf3e5ec611c3b43fac 232 Gene3D G3DSA:2.160.10.10 83 230 6.9E-42 T 29-03-2018 SPSF3K_RS00890 d867cde44aa608cf3e5ec611c3b43fac 232 Gene3D G3DSA:3.30.70.250 5 82 3.4E-25 T 29-03-2018 SPSF3K_RS00890 d867cde44aa608cf3e5ec611c3b43fac 232 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 4.5E-8 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS00890 d867cde44aa608cf3e5ec611c3b43fac 232 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 161 196 4.0E-12 T 29-03-2018 IPR001451 Hexapeptide repeat SPSF3K_RS00890 d867cde44aa608cf3e5ec611c3b43fac 232 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 6 82 1.3E-20 T 29-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 SPSF3K_RS03725 71aba61f0f9a992ac19ec0ac664c18c9 215 Pfam PF07853 Protein of unknown function (DUF1648) 13 60 1.6E-20 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 SPSF3K_RS03725 71aba61f0f9a992ac19ec0ac664c18c9 215 PIRSF PIRSF038959 1 211 9.3E-40 T 29-03-2018 IPR026272 Immunity protein SdpI SPSF3K_RS03725 71aba61f0f9a992ac19ec0ac664c18c9 215 Pfam PF13630 SdpI/YhfL protein family 134 202 4.7E-20 T 29-03-2018 IPR025962 SdpI/YhfL protein family SPSF3K_RS02355 229891eef26e2212cc83ad34b7b18c5a 257 SUPERFAMILY SSF46955 4 112 2.2E-20 T 29-03-2018 IPR009061 Putative DNA-binding domain SPSF3K_RS02355 229891eef26e2212cc83ad34b7b18c5a 257 Gene3D G3DSA:1.10.1660.10 2 137 2.7E-18 T 29-03-2018 SPSF3K_RS02355 229891eef26e2212cc83ad34b7b18c5a 257 Pfam PF00376 MerR family regulatory protein 6 44 2.7E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02355 229891eef26e2212cc83ad34b7b18c5a 257 SMART SM00422 5 75 5.4E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS02355 229891eef26e2212cc83ad34b7b18c5a 257 ProSitePatterns PS00552 MerR-type HTH domain signature. 8 30 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPSF3K_RS03970 5b2ae8d02bd1c7a15e666c8b150a4b5e 400 Gene3D G3DSA:1.20.1250.20 201 393 1.2E-25 T 29-03-2018 SPSF3K_RS03970 5b2ae8d02bd1c7a15e666c8b150a4b5e 400 PRINTS PR01035 Tetracycline resistance protein signature 107 128 1.5E-9 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SPSF3K_RS03970 5b2ae8d02bd1c7a15e666c8b150a4b5e 400 PRINTS PR01035 Tetracycline resistance protein signature 137 159 1.5E-9 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SPSF3K_RS03970 5b2ae8d02bd1c7a15e666c8b150a4b5e 400 PRINTS PR01035 Tetracycline resistance protein signature 340 363 1.5E-9 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SPSF3K_RS03970 5b2ae8d02bd1c7a15e666c8b150a4b5e 400 PRINTS PR01035 Tetracycline resistance protein signature 49 68 1.5E-9 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SPSF3K_RS03970 5b2ae8d02bd1c7a15e666c8b150a4b5e 400 SUPERFAMILY SSF103473 8 395 1.22E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS03970 5b2ae8d02bd1c7a15e666c8b150a4b5e 400 Pfam PF07690 Major Facilitator Superfamily 14 302 5.8E-41 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS03970 5b2ae8d02bd1c7a15e666c8b150a4b5e 400 Gene3D G3DSA:1.20.1250.20 2 197 2.8E-36 T 29-03-2018 SPSF3K_RS01075 a8ce052d737ba36142ede4f2fa9fc74a 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 283 3.8E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01075 a8ce052d737ba36142ede4f2fa9fc74a 294 SUPERFAMILY SSF161098 57 283 5.63E-55 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01075 a8ce052d737ba36142ede4f2fa9fc74a 294 Gene3D G3DSA:1.20.58.370 7 46 1.1E-4 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain SPSF3K_RS01075 a8ce052d737ba36142ede4f2fa9fc74a 294 Gene3D G3DSA:1.10.3720.10 65 293 2.1E-37 T 29-03-2018 SPSF3K_RS06815 75ddcfe277ae951a7506c63c6dcba464 651 PIRSF PIRSF018968 1 651 8.2E-73 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 SPSF3K_RS06815 75ddcfe277ae951a7506c63c6dcba464 651 Pfam PF02687 FtsX-like permease family 558 642 1.3E-5 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SPSF3K_RS01385 0141a8ca256593b87b3a41a647e1798d 454 Gene3D G3DSA:1.10.4100.10 1 308 3.0E-74 T 29-03-2018 SPSF3K_RS01385 0141a8ca256593b87b3a41a647e1798d 454 SUPERFAMILY SSF103378 7 451 1.96E-97 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 SPSF3K_RS01385 0141a8ca256593b87b3a41a647e1798d 454 Pfam PF03972 MmgE/PrpD family 8 437 5.7E-113 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 PIRSF PIRSF002133 1 137 2.5E-47 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 Pfam PF00164 Ribosomal protein S12/S23 31 136 7.1E-37 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 SUPERFAMILY SSF50249 2 136 4.28E-47 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 Gene3D G3DSA:2.40.50.140 1 137 3.3E-62 T 29-03-2018 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.1E-57 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.1E-57 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.1E-57 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.1E-57 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.1E-57 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.1E-57 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 4.3E-66 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01190 85985e609bb28915bfad8ce2927e0cf4 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 39.623 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS07735 e157bfe64f965cc251a9d9cf88e6afbe 230 Gene3D G3DSA:3.30.1890.10 43 156 3.9E-9 T 29-03-2018 SPSF3K_RS07735 e157bfe64f965cc251a9d9cf88e6afbe 230 Pfam PF02706 Chain length determinant protein 10 98 5.2E-22 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 SPSF3K_RS08505 36129cf2db44eafec59a659356875255 165 Pfam PF13185 GAF domain 51 148 1.4E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 SPSF3K_RS08505 36129cf2db44eafec59a659356875255 165 Gene3D G3DSA:3.30.450.40 2 151 1.3E-18 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS08505 36129cf2db44eafec59a659356875255 165 SUPERFAMILY SSF55781 3 150 2.14E-35 T 29-03-2018 IPR029016 GAF domain-like SPSF3K_RS10115 3dbe8c9e65b984129bac3e76349e448b 144 Pfam PF01047 MarR family 34 91 4.8E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS10115 3dbe8c9e65b984129bac3e76349e448b 144 Gene3D G3DSA:1.10.10.10 5 144 7.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10115 3dbe8c9e65b984129bac3e76349e448b 144 SUPERFAMILY SSF46785 9 142 6.12E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS10115 3dbe8c9e65b984129bac3e76349e448b 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS10115 3dbe8c9e65b984129bac3e76349e448b 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 1.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS10115 3dbe8c9e65b984129bac3e76349e448b 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 1.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS10115 3dbe8c9e65b984129bac3e76349e448b 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.2E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS10115 3dbe8c9e65b984129bac3e76349e448b 144 SMART SM00347 26 126 8.5E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPSF3K_RS02465 606dbc6c254ea2c0d76c36d2a92098c8 165 SUPERFAMILY SSF52540 1 132 6.03E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS02465 606dbc6c254ea2c0d76c36d2a92098c8 165 Pfam PF07931 Chloramphenicol phosphotransferase-like protein 2 37 1.5E-5 T 29-03-2018 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 SPSF3K_RS02465 606dbc6c254ea2c0d76c36d2a92098c8 165 Gene3D G3DSA:3.40.50.300 1 165 9.7E-13 T 29-03-2018 SPSF3K_RS00540 a18e819cbece4d97707bd4d79108fb42 108 SUPERFAMILY SSF46785 2 105 9.28E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00540 a18e819cbece4d97707bd4d79108fb42 108 Gene3D G3DSA:1.10.10.10 14 108 2.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00540 a18e819cbece4d97707bd4d79108fb42 108 Pfam PF01638 HxlR-like helix-turn-helix 16 104 4.6E-34 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type SPSF3K_RS06370 254d7c2822b6172057abd09179db2526 282 SUPERFAMILY SSF53335 3 272 1.43E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPSF3K_RS06370 254d7c2822b6172057abd09179db2526 282 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 275 37.689 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SPSF3K_RS06370 254d7c2822b6172057abd09179db2526 282 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SPSF3K_RS06370 254d7c2822b6172057abd09179db2526 282 Gene3D G3DSA:3.40.50.150 80 278 2.6E-38 T 29-03-2018 SPSF3K_RS06370 254d7c2822b6172057abd09179db2526 282 Pfam PF05175 Methyltransferase small domain 103 188 1.1E-17 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 SPSF3K_RS06370 254d7c2822b6172057abd09179db2526 282 Gene3D G3DSA:1.10.8.10 1 79 1.0E-10 T 29-03-2018 SPSF3K_RS06370 254d7c2822b6172057abd09179db2526 282 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 3 273 2.7E-64 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SPSF3K_RS06370 254d7c2822b6172057abd09179db2526 282 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 27 271 1.3E-77 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SPSF3K_RS01375 d30f83d3d11d641b70b366c6221e7a6b 362 Gene3D G3DSA:2.60.40.1240 27 170 3.9E-17 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain SPSF3K_RS01375 d30f83d3d11d641b70b366c6221e7a6b 362 Pfam PF11611 Domain of unknown function (DUF4352) 30 141 3.2E-10 T 29-03-2018 IPR029051 Domain of unknown function DUF4352 SPSF3K_RS10395 1991356a13c0b6ae7fb6748ea8c3eb74 127 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 127 33.455 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10395 1991356a13c0b6ae7fb6748ea8c3eb74 127 Gene3D G3DSA:3.30.420.80 1 127 1.1E-44 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10395 1991356a13c0b6ae7fb6748ea8c3eb74 127 ProSitePatterns PS00054 Ribosomal protein S11 signature. 95 117 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site SPSF3K_RS10395 1991356a13c0b6ae7fb6748ea8c3eb74 127 PIRSF PIRSF002131 2 127 6.5E-52 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10395 1991356a13c0b6ae7fb6748ea8c3eb74 127 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 8 124 3.2E-58 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10395 1991356a13c0b6ae7fb6748ea8c3eb74 127 SUPERFAMILY SSF53137 12 127 6.54E-49 T 29-03-2018 SPSF3K_RS10395 1991356a13c0b6ae7fb6748ea8c3eb74 127 Pfam PF00411 Ribosomal protein S11 17 126 1.8E-51 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SPSF3K_RS10000 118828db19c6730071a4aa70637b0089 429 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 81 237 2.1E-48 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SPSF3K_RS10000 118828db19c6730071a4aa70637b0089 429 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 80 237 2.6E-45 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SPSF3K_RS09370 bdbdb849ee0330d802644a15924a85d0 206 Gene3D G3DSA:3.40.630.30 2 180 3.5E-25 T 29-03-2018 SPSF3K_RS09370 bdbdb849ee0330d802644a15924a85d0 206 SUPERFAMILY SSF55729 4 170 1.63E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS09370 bdbdb849ee0330d802644a15924a85d0 206 Pfam PF13420 Acetyltransferase (GNAT) domain 5 165 4.1E-40 T 29-03-2018 SPSF3K_RS04550 9ed9dd281d805758e8ef0a71b9d83975 145 SUPERFAMILY SSF53590 1 118 1.44E-10 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SPSF3K_RS04550 9ed9dd281d805758e8ef0a71b9d83975 145 Gene3D G3DSA:3.90.245.10 1 124 7.0E-7 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain SPSF3K_RS04385 beb7505044bf3236a48ee1fdf439f037 210 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 201 8.0E-49 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS04385 beb7505044bf3236a48ee1fdf439f037 210 SMART SM00855 2 160 8.4E-18 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 SPSF3K_RS04385 beb7505044bf3236a48ee1fdf439f037 210 PIRSF PIRSF000709 1 167 2.7E-10 T 29-03-2018 SPSF3K_RS04385 beb7505044bf3236a48ee1fdf439f037 210 SUPERFAMILY SSF53254 1 208 5.01E-51 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS04385 beb7505044bf3236a48ee1fdf439f037 210 Gene3D G3DSA:3.40.50.1240 1 210 5.6E-47 T 29-03-2018 IPR029033 Histidine phosphatase superfamily SPSF3K_RS08455 14619ef05fca98f83785d5c302c5b834 310 Pfam PF03631 Virulence factor BrkB 29 282 3.1E-46 T 29-03-2018 IPR017039 Virulence factor BrkB SPSF3K_RS08455 14619ef05fca98f83785d5c302c5b834 310 PIRSF PIRSF035875 1 299 2.9E-59 T 29-03-2018 IPR017039 Virulence factor BrkB SPSF3K_RS03700 a00447d87288512c439fe1b1559a17d3 138 SUPERFAMILY SSF54593 4 136 8.11E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS03700 a00447d87288512c439fe1b1559a17d3 138 Gene3D G3DSA:3.10.180.10 1 138 1.6E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS03700 a00447d87288512c439fe1b1559a17d3 138 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 132 8.5E-9 T 29-03-2018 IPR028973 PhnB-like SPSF3K_RS04220 2ace6c55c2e521c73b7bbe9b5d8bc970 293 SUPERFAMILY SSF53850 180 291 4.56E-30 T 29-03-2018 SPSF3K_RS04220 2ace6c55c2e521c73b7bbe9b5d8bc970 293 Pfam PF12849 PBP superfamily domain 33 156 8.0E-10 T 29-03-2018 IPR024370 PBP domain SPSF3K_RS04220 2ace6c55c2e521c73b7bbe9b5d8bc970 293 Pfam PF12849 PBP superfamily domain 181 291 1.8E-23 T 29-03-2018 IPR024370 PBP domain SPSF3K_RS04220 2ace6c55c2e521c73b7bbe9b5d8bc970 293 SUPERFAMILY SSF53850 36 180 2.72E-31 T 29-03-2018 SPSF3K_RS04220 2ace6c55c2e521c73b7bbe9b5d8bc970 293 Gene3D G3DSA:3.40.190.10 184 293 4.7E-31 T 29-03-2018 SPSF3K_RS04220 2ace6c55c2e521c73b7bbe9b5d8bc970 293 Gene3D G3DSA:3.40.190.10 39 183 1.6E-20 T 29-03-2018 SPSF3K_RS07120 17447f90c0cc89b1e0f00bafaff64cfb 198 PIRSF PIRSF036177 1 198 3.5E-81 T 29-03-2018 IPR017043 Type I restriction-modification system, specificity subunit, predicted SPSF3K_RS07120 17447f90c0cc89b1e0f00bafaff64cfb 198 Gene3D G3DSA:3.90.220.20 7 161 1.8E-28 T 29-03-2018 SPSF3K_RS07120 17447f90c0cc89b1e0f00bafaff64cfb 198 Pfam PF01420 Type I restriction modification DNA specificity domain 14 162 5.2E-6 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 SPSF3K_RS07120 17447f90c0cc89b1e0f00bafaff64cfb 198 SUPERFAMILY SSF116734 11 186 1.44E-21 T 29-03-2018 SPSF3K_RS01215 03a1046c5049574c4064ce58b9d6d5aa 171 Pfam PF06081 Aromatic acid exporter family member 1 11 157 1.7E-12 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 SPSF3K_RS01990 1a06391a4888a1804f13e30223093c2e 217 Pfam PF02517 CAAX protease self-immunity 117 204 1.7E-18 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 SPSF3K_RS08020 40a232eead381d0e3b8c763502e3dbef 228 Pfam PF00413 Matrixin 101 225 1.2E-7 T 29-03-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 SPSF3K_RS08020 40a232eead381d0e3b8c763502e3dbef 228 SUPERFAMILY SSF55486 82 225 5.63E-21 T 29-03-2018 SPSF3K_RS08020 40a232eead381d0e3b8c763502e3dbef 228 Gene3D G3DSA:3.40.390.10 41 228 1.2E-17 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 Gene3D G3DSA:3.40.50.720 58 267 9.5E-56 T 29-03-2018 SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 Gene3D G3DSA:3.40.50.720 6 57 1.4E-11 T 29-03-2018 SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 SUPERFAMILY SSF51735 12 262 4.44E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.1E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.1E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 1.1E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 2.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.1E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR SPSF3K_RS01320 d21f1d1838dc98ebefbdba8016ebb9df 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 260 2.8E-64 T 29-03-2018 SPSF3K_RS07280 1057e7d9a1622fc82216dc852a36f229 232 SMART SM00382 29 204 3.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS07280 1057e7d9a1622fc82216dc852a36f229 232 Pfam PF00005 ABC transporter 21 155 7.6E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS07280 1057e7d9a1622fc82216dc852a36f229 232 Gene3D G3DSA:3.40.50.300 1 231 7.8E-53 T 29-03-2018 SPSF3K_RS07280 1057e7d9a1622fc82216dc852a36f229 232 SUPERFAMILY SSF52540 3 219 1.78E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05895 6dc7a2ea394745964ffec0fc07968d89 298 Gene3D G3DSA:3.40.50.300 1 298 5.2E-41 T 29-03-2018 SPSF3K_RS05895 6dc7a2ea394745964ffec0fc07968d89 298 Pfam PF13614 AAA domain 42 214 4.0E-32 T 29-03-2018 IPR025669 AAA domain SPSF3K_RS05895 6dc7a2ea394745964ffec0fc07968d89 298 SUPERFAMILY SSF52540 38 292 1.77E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09305 08a0848aae60115b899ec49f3bdc00fe 202 Pfam PF09335 SNARE associated Golgi protein 37 162 3.5E-19 T 29-03-2018 IPR032816 SNARE associated Golgi protein SPSF3K_RS08010 e58f7181fe77591dcf7984550f69529f 322 SUPERFAMILY SSF52518 4 322 2.95E-102 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold SPSF3K_RS08010 e58f7181fe77591dcf7984550f69529f 322 Gene3D G3DSA:3.40.50.970 1 322 7.1E-92 T 29-03-2018 SPSF3K_RS08010 e58f7181fe77591dcf7984550f69529f 322 Pfam PF00676 Dehydrogenase E1 component 15 311 7.9E-87 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 SPSF3K_RS07720 4e2dd5c3b915d86d844000a5e732d31e 200 Pfam PF02397 Bacterial sugar transferase 6 184 1.8E-62 T 29-03-2018 IPR003362 Bacterial sugar transferase SPSF3K_RS06395 5d2ec2c0c237fe2c0db877f2f9af4aa1 200 SUPERFAMILY SSF53955 33 149 1.29E-10 T 29-03-2018 IPR023346 Lysozyme-like domain SPSF3K_RS06395 5d2ec2c0c237fe2c0db877f2f9af4aa1 200 Pfam PF13702 Lysozyme-like 29 190 7.9E-57 T 29-03-2018 SPSF3K_RS06395 5d2ec2c0c237fe2c0db877f2f9af4aa1 200 Gene3D G3DSA:1.10.530.10 22 184 1.8E-9 T 29-03-2018 SPSF3K_RS03345 67bbd65d771b63a6d2eec6050cf9a17e 155 Gene3D G3DSA:3.10.580.10 2 153 2.1E-19 T 29-03-2018 SPSF3K_RS03345 67bbd65d771b63a6d2eec6050cf9a17e 155 Pfam PF00571 CBS domain 36 70 0.0018 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS03345 67bbd65d771b63a6d2eec6050cf9a17e 155 Pfam PF00571 CBS domain 88 137 1.7E-7 T 29-03-2018 IPR000644 CBS domain SPSF3K_RS03345 67bbd65d771b63a6d2eec6050cf9a17e 155 SUPERFAMILY SSF54631 16 138 1.77E-23 T 29-03-2018 SPSF3K_RS04645 f4a21964a988a63e79d19f1cf97fef8c 146 Gene3D G3DSA:3.40.630.30 1 146 5.2E-29 T 29-03-2018 SPSF3K_RS04645 f4a21964a988a63e79d19f1cf97fef8c 146 SUPERFAMILY SSF55729 1 146 1.61E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS04645 f4a21964a988a63e79d19f1cf97fef8c 146 Pfam PF13673 Acetyltransferase (GNAT) domain 22 144 2.0E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS06725 2f4a4787efccc234d3e686fad7d1a9c1 140 Pfam PF05128 Domain of unknown function (DUF697) 7 134 3.8E-8 T 29-03-2018 IPR021147 Protein of unknown function DUF697 SPSF3K_RS01165 03f36b9428e2af918475fdd1312d3f74 423 Gene3D G3DSA:1.20.5.1230 23 409 1.5E-16 T 29-03-2018 SPSF3K_RS01165 03f36b9428e2af918475fdd1312d3f74 423 SUPERFAMILY SSF58113 32 154 1.16E-5 T 29-03-2018 SPSF3K_RS01165 03f36b9428e2af918475fdd1312d3f74 423 Pfam PF02646 RmuC family 117 407 2.4E-71 T 29-03-2018 IPR003798 DNA recombination RmuC SPSF3K_RS09920 f502f0ca519ea19fcb853d3551664276 66 Gene3D G3DSA:3.30.70.100 1 66 3.6E-17 T 29-03-2018 SPSF3K_RS09920 f502f0ca519ea19fcb853d3551664276 66 SUPERFAMILY SSF55008 1 63 3.93E-14 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS09920 f502f0ca519ea19fcb853d3551664276 66 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SPSF3K_RS09920 f502f0ca519ea19fcb853d3551664276 66 Pfam PF00403 Heavy-metal-associated domain 5 61 4.5E-15 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPSF3K_RS08860 ea99c24036505654ceb7864dd98ae7d0 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 222 3.9E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS08860 ea99c24036505654ceb7864dd98ae7d0 229 SUPERFAMILY SSF161098 10 208 2.49E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS08860 ea99c24036505654ceb7864dd98ae7d0 229 Gene3D G3DSA:1.10.3720.10 1 228 2.5E-39 T 29-03-2018 SPSF3K_RS08860 ea99c24036505654ceb7864dd98ae7d0 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 117 6.7E-17 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPSF3K_RS01065 66a3881073606c4051adad08cd180361 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 3.0E-15 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01065 66a3881073606c4051adad08cd180361 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS01065 66a3881073606c4051adad08cd180361 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 2 44 9.9E-21 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01065 66a3881073606c4051adad08cd180361 44 Pfam PF00468 Ribosomal protein L34 2 44 3.0E-22 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS01065 66a3881073606c4051adad08cd180361 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.594 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 SPSF3K_RS00695 70d77c08b5987bd6cbd418af94721cfd 300 Pfam PF00849 RNA pseudouridylate synthase 101 247 2.2E-30 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS00695 70d77c08b5987bd6cbd418af94721cfd 300 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS00695 70d77c08b5987bd6cbd418af94721cfd 300 SUPERFAMILY SSF55120 94 291 2.08E-57 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS00695 70d77c08b5987bd6cbd418af94721cfd 300 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 50 293 1.0E-59 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPSF3K_RS00695 70d77c08b5987bd6cbd418af94721cfd 300 Gene3D G3DSA:3.30.2350.10 92 300 7.6E-62 T 29-03-2018 SPSF3K_RS09375 0a35ac99196f0d8de5d5cd84802a4a2e 224 Gene3D G3DSA:3.30.70.100 1 102 1.2E-9 T 29-03-2018 SPSF3K_RS09375 0a35ac99196f0d8de5d5cd84802a4a2e 224 Pfam PF03992 Antibiotic biosynthesis monooxygenase 9 83 7.7E-8 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SPSF3K_RS09375 0a35ac99196f0d8de5d5cd84802a4a2e 224 Pfam PF03992 Antibiotic biosynthesis monooxygenase 121 194 1.5E-8 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain SPSF3K_RS09375 0a35ac99196f0d8de5d5cd84802a4a2e 224 SUPERFAMILY SSF54909 121 206 4.92E-14 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SPSF3K_RS09375 0a35ac99196f0d8de5d5cd84802a4a2e 224 SUPERFAMILY SSF54909 8 94 6.71E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel SPSF3K_RS09375 0a35ac99196f0d8de5d5cd84802a4a2e 224 Gene3D G3DSA:3.30.70.100 110 208 6.2E-11 T 29-03-2018 SPSF3K_RS06515 49d6d51eaf099c5cf4404cbcaac3adee 459 Gene3D G3DSA:3.30.460.10 19 188 2.5E-10 T 29-03-2018 SPSF3K_RS00720 b063b827b96e0c8aa43cd9d5cc8ed18a 58 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 3 52 1.9E-11 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 SPSF3K_RS00720 b063b827b96e0c8aa43cd9d5cc8ed18a 58 Gene3D G3DSA:1.20.5.1030 1 51 1.2E-13 T 29-03-2018 SPSF3K_RS00720 b063b827b96e0c8aa43cd9d5cc8ed18a 58 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 3 51 2.8E-11 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 SPSF3K_RS06760 65ac89ded39517e333886ad9560e62e9 614 Gene3D G3DSA:3.40.50.1110 421 608 1.2E-10 T 29-03-2018 SPSF3K_RS06760 65ac89ded39517e333886ad9560e62e9 614 Pfam PF01757 Acyltransferase family 4 348 3.3E-16 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SPSF3K_RS06760 65ac89ded39517e333886ad9560e62e9 614 SUPERFAMILY SSF52266 447 607 2.11E-7 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain SPSF3K_RS06785 7d277626f42255ad4829a7a342087393 390 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 17 346 2.8E-67 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SPSF3K_RS06785 7d277626f42255ad4829a7a342087393 390 SUPERFAMILY SSF51395 2 349 5.5E-86 T 29-03-2018 SPSF3K_RS06785 7d277626f42255ad4829a7a342087393 390 Gene3D G3DSA:3.20.20.70 1 374 2.2E-88 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS03000 c3519256e0b23e023c13521840263ae6 634 Pfam PF09972 Predicted membrane protein (DUF2207) 27 562 9.1E-74 T 29-03-2018 IPR018702 Protein of unknown function DUF2207, membrane SPSF3K_RS06390 7eba1fb03a39d6096e605474d1a5baeb 325 Pfam PF04245 37-kD nucleoid-associated bacterial protein 11 321 7.9E-37 T 29-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 SPSF3K_RS03750 737263c571f7f12fbeafa43f4e357f08 452 Pfam PF05525 Branched-chain amino acid transport protein 3 431 1.6E-128 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 SPSF3K_RS03750 737263c571f7f12fbeafa43f4e357f08 452 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 10 418 2.4E-103 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 SPSF3K_RS07730 76e3244bdedb54751633737b6a0c9c28 239 SUPERFAMILY SSF52540 36 213 1.06E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS07730 76e3244bdedb54751633737b6a0c9c28 239 Pfam PF13614 AAA domain 36 178 4.5E-17 T 29-03-2018 IPR025669 AAA domain SPSF3K_RS07730 76e3244bdedb54751633737b6a0c9c28 239 Gene3D G3DSA:3.40.50.300 7 226 5.8E-34 T 29-03-2018 SPSF3K_RS07730 76e3244bdedb54751633737b6a0c9c28 239 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 19 222 1.2E-92 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 Pfam PF00406 Adenylate kinase 5 187 1.8E-55 T 29-03-2018 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 Hamap MF_00235 Adenylate kinase [adk]. 1 210 47.477 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 PRINTS PR00094 Adenylate kinase signature 4 17 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 PRINTS PR00094 Adenylate kinase signature 157 172 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 PRINTS PR00094 Adenylate kinase signature 32 46 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 PRINTS PR00094 Adenylate kinase signature 82 98 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 PRINTS PR00094 Adenylate kinase signature 174 188 2.0E-30 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 Gene3D G3DSA:3.40.50.300 1 213 4.6E-55 T 29-03-2018 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 6.0E-73 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 SUPERFAMILY SSF52540 159 211 3.3E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 SUPERFAMILY SSF52540 1 128 3.3E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS10415 49f813e1cf60cbb2bcce61649bb3ad14 213 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 SPSF3K_RS02540 03b930895e44d964e626cc0609509831 331 Gene3D G3DSA:3.40.50.720 2 166 1.6E-32 T 29-03-2018 SPSF3K_RS02540 03b930895e44d964e626cc0609509831 331 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 328 3.4E-128 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 SPSF3K_RS02540 03b930895e44d964e626cc0609509831 331 Gene3D G3DSA:3.90.25.10 167 331 5.4E-38 T 29-03-2018 SPSF3K_RS02540 03b930895e44d964e626cc0609509831 331 SUPERFAMILY SSF51735 1 330 7.67E-96 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS02540 03b930895e44d964e626cc0609509831 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 254 8.2E-60 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 SPSF3K_RS06505 d6025daa0e998442a7b1d2f7a237019b 382 Gene3D G3DSA:1.20.91.10 226 309 9.8E-13 T 29-03-2018 SPSF3K_RS06505 d6025daa0e998442a7b1d2f7a237019b 382 Pfam PF00999 Sodium/hydrogen exchanger family 8 375 1.2E-76 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SPSF3K_RS03335 263bd6bfcb8af12f0544bdd669e189fd 332 SUPERFAMILY SSF52972 132 325 1.1E-63 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SPSF3K_RS03335 263bd6bfcb8af12f0544bdd669e189fd 332 Gene3D G3DSA:3.90.950.10 112 328 8.6E-72 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like SPSF3K_RS03335 263bd6bfcb8af12f0544bdd669e189fd 332 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 133 324 1.3E-55 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 SPSF3K_RS03335 263bd6bfcb8af12f0544bdd669e189fd 332 Pfam PF01725 Ham1 family 134 322 1.4E-54 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 SPSF3K_RS03335 263bd6bfcb8af12f0544bdd669e189fd 332 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 132 326 46.999 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 SPSF3K_RS01905 f25df4ee6a6b2f8c9946c6341077de07 271 Gene3D G3DSA:1.10.3470.10 3 269 6.9E-26 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS01905 f25df4ee6a6b2f8c9946c6341077de07 271 SUPERFAMILY SSF81345 3 260 1.31E-36 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SPSF3K_RS01905 f25df4ee6a6b2f8c9946c6341077de07 271 Pfam PF00950 ABC 3 transport family 6 262 6.6E-75 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 SPSF3K_RS02350 32d6a02ecd62c8efdcdf0f9df0c35c4a 199 Pfam PF11193 Protein of unknown function (DUF2812) 11 119 1.3E-22 T 29-03-2018 IPR021359 Protein of unknown function DUF2812 SPSF3K_RS04075 31f8e0d79f1cd287ba90909a5951ecb8 443 Gene3D G3DSA:3.40.50.2000 1 193 5.3E-16 T 29-03-2018 SPSF3K_RS04075 31f8e0d79f1cd287ba90909a5951ecb8 443 SUPERFAMILY SSF53756 1 375 5.38E-70 T 29-03-2018 SPSF3K_RS04075 31f8e0d79f1cd287ba90909a5951ecb8 443 Gene3D G3DSA:3.40.50.2000 194 365 1.7E-35 T 29-03-2018 SPSF3K_RS04075 31f8e0d79f1cd287ba90909a5951ecb8 443 Pfam PF13439 Glycosyltransferase Family 4 15 182 7.6E-29 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SPSF3K_RS04075 31f8e0d79f1cd287ba90909a5951ecb8 443 Pfam PF00534 Glycosyl transferases group 1 196 345 5.0E-29 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SPSF3K_RS01805 bef3a1e1d80e53d594bf7c71f2faeaf0 186 Gene3D G3DSA:1.10.10.60 28 132 0.011 T 29-03-2018 SPSF3K_RS01805 bef3a1e1d80e53d594bf7c71f2faeaf0 186 Gene3D G3DSA:3.30.420.10 139 186 1.1E-4 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 SPSF3K_RS01355 c7b3b976bbab0187586b581d5781cd65 392 SUPERFAMILY SSF103473 9 380 4.05E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS01355 c7b3b976bbab0187586b581d5781cd65 392 Gene3D G3DSA:1.20.1250.20 1 180 3.0E-21 T 29-03-2018 SPSF3K_RS01355 c7b3b976bbab0187586b581d5781cd65 392 Pfam PF07690 Major Facilitator Superfamily 13 344 1.2E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS01355 c7b3b976bbab0187586b581d5781cd65 392 Gene3D G3DSA:1.20.1250.20 190 381 4.8E-19 T 29-03-2018 SPSF3K_RS10455 f52220f9c37e9cc9513810ab5aafba9b 61 Pfam PF00253 Ribosomal protein S14p/S29e 13 60 8.1E-24 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPSF3K_RS10455 f52220f9c37e9cc9513810ab5aafba9b 61 Gene3D G3DSA:4.10.830.10 12 61 5.2E-21 T 29-03-2018 SPSF3K_RS10455 f52220f9c37e9cc9513810ab5aafba9b 61 SUPERFAMILY SSF57716 4 61 9.98E-21 T 29-03-2018 SPSF3K_RS10455 f52220f9c37e9cc9513810ab5aafba9b 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 24.86 T 29-03-2018 IPR023053 Ribosomal protein S14, type Z SPSF3K_RS10455 f52220f9c37e9cc9513810ab5aafba9b 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 SPSF3K_RS04595 b1cdeeef1b5e1151b52064ac80ed9f64 326 Pfam PF01791 DeoC/LacD family aldolase 20 281 7.9E-78 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SPSF3K_RS04595 b1cdeeef1b5e1151b52064ac80ed9f64 326 Gene3D G3DSA:3.20.20.70 4 326 1.0E-79 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS04595 b1cdeeef1b5e1151b52064ac80ed9f64 326 TIGRFAM TIGR01232 lacD: tagatose 1,6-diphosphate aldolase 4 324 8.7E-184 T 29-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 SPSF3K_RS04595 b1cdeeef1b5e1151b52064ac80ed9f64 326 Hamap MF_00734 Tagatose 1,6-diphosphate aldolase [lacD]. 1 326 210.205 T 29-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 SPSF3K_RS04595 b1cdeeef1b5e1151b52064ac80ed9f64 326 SUPERFAMILY SSF51569 8 321 9.16E-69 T 29-03-2018 SPSF3K_RS04595 b1cdeeef1b5e1151b52064ac80ed9f64 326 SMART SM01133 20 282 1.6E-30 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 SPSF3K_RS04610 e5c004746bfd925f243f50ab99c876ac 161 Pfam PF03830 PTS system sorbose subfamily IIB component 3 149 1.3E-47 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPSF3K_RS04610 e5c004746bfd925f243f50ab99c876ac 161 SUPERFAMILY SSF52728 1 160 2.35E-50 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPSF3K_RS04610 e5c004746bfd925f243f50ab99c876ac 161 Gene3D G3DSA:3.40.35.10 2 158 6.6E-51 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPSF3K_RS03200 4c81d5f26aa2fd71c1cb8932d7624af1 230 Gene3D G3DSA:1.10.3720.10 21 230 2.7E-23 T 29-03-2018 SPSF3K_RS03200 4c81d5f26aa2fd71c1cb8932d7624af1 230 SUPERFAMILY SSF161098 22 217 3.01E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS03200 4c81d5f26aa2fd71c1cb8932d7624af1 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 53 228 2.6E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS09400 16223742ad67e2899f9177bc7d45a5b7 163 Pfam PF08534 Redoxin 19 154 5.6E-23 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 SPSF3K_RS09400 16223742ad67e2899f9177bc7d45a5b7 163 ProSitePatterns PS01265 Tpx family signature. 82 93 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 SPSF3K_RS09400 16223742ad67e2899f9177bc7d45a5b7 163 Gene3D G3DSA:3.40.30.10 6 163 2.1E-24 T 29-03-2018 SPSF3K_RS09400 16223742ad67e2899f9177bc7d45a5b7 163 SUPERFAMILY SSF52833 4 158 4.05E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS04185 8a7a4090cde6647e708e196ef78eba27 165 Pfam PF03692 Putative zinc- or iron-chelating domain 53 141 4.0E-16 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein SPSF3K_RS01730 8687c3ea45db3ad59fc943f3b84d7402 117 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 115 6.0E-40 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPSF3K_RS01730 8687c3ea45db3ad59fc943f3b84d7402 117 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 22.207 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPSF3K_RS01730 8687c3ea45db3ad59fc943f3b84d7402 117 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 6 110 3.3E-21 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SPSF3K_RS01730 8687c3ea45db3ad59fc943f3b84d7402 117 SUPERFAMILY SSF56214 1 115 7.46E-34 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SPSF3K_RS01730 8687c3ea45db3ad59fc943f3b84d7402 117 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 116 3.6E-25 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPSF3K_RS01730 8687c3ea45db3ad59fc943f3b84d7402 117 Gene3D G3DSA:3.90.470.20 1 117 2.8E-32 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 SPSF3K_RS01730 8687c3ea45db3ad59fc943f3b84d7402 117 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 116 4.3E-26 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPSF3K_RS00520 043b4d028c77300d60c60936f9c70b1e 164 SUPERFAMILY SSF55729 1 143 1.63E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS00520 043b4d028c77300d60c60936f9c70b1e 164 Pfam PF13302 Acetyltransferase (GNAT) domain 2 145 2.4E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS00520 043b4d028c77300d60c60936f9c70b1e 164 Gene3D G3DSA:3.40.630.30 1 147 2.0E-15 T 29-03-2018 SPSF3K_RS07275 bb9590ebf2a54eb7acc0a0588635b5d4 122 SUPERFAMILY SSF46785 4 84 3.47E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS07275 bb9590ebf2a54eb7acc0a0588635b5d4 122 SMART SM00345 15 74 1.6E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS07275 bb9590ebf2a54eb7acc0a0588635b5d4 122 Gene3D G3DSA:1.10.287.100 78 120 8.9E-5 T 29-03-2018 SPSF3K_RS07275 bb9590ebf2a54eb7acc0a0588635b5d4 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 9.8E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPSF3K_RS07275 bb9590ebf2a54eb7acc0a0588635b5d4 122 Gene3D G3DSA:1.10.10.10 1 76 1.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS03230 2d419fe1f27ff55078cdec0bb72e5b12 177 Pfam PF02620 Uncharacterized ACR, COG1399 54 174 4.3E-19 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD SPSF3K_RS09295 71bb9c04c744daef11301ab4e47b58ae 297 Pfam PF00005 ABC transporter 17 156 6.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS09295 71bb9c04c744daef11301ab4e47b58ae 297 SMART SM00382 26 204 1.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS09295 71bb9c04c744daef11301ab4e47b58ae 297 Pfam PF13732 Domain of unknown function (DUF4162) 210 290 5.5E-11 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 SPSF3K_RS09295 71bb9c04c744daef11301ab4e47b58ae 297 SUPERFAMILY SSF52540 2 223 8.45E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS09295 71bb9c04c744daef11301ab4e47b58ae 297 Gene3D G3DSA:3.40.50.300 1 252 5.9E-57 T 29-03-2018 SPSF3K_RS09295 71bb9c04c744daef11301ab4e47b58ae 297 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS07075 81473f2e1920f400bd83e8a93262bd98 311 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 20 305 2.1E-89 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 SPSF3K_RS07075 81473f2e1920f400bd83e8a93262bd98 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 304 5.0E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS07075 81473f2e1920f400bd83e8a93262bd98 311 Gene3D G3DSA:1.10.3720.10 12 299 8.9E-40 T 29-03-2018 SPSF3K_RS07075 81473f2e1920f400bd83e8a93262bd98 311 SUPERFAMILY SSF161098 23 301 3.27E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04640 1cc4f39f3f59159baee3302e0f6d9e29 311 SUPERFAMILY SSF64182 14 302 3.53E-72 T 29-03-2018 SPSF3K_RS04640 1cc4f39f3f59159baee3302e0f6d9e29 311 Gene3D G3DSA:3.90.1640.10 1 193 2.2E-42 T 29-03-2018 SPSF3K_RS04640 1cc4f39f3f59159baee3302e0f6d9e29 311 Pfam PF01368 DHH family 17 152 2.4E-11 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 SPSF3K_RS04640 1cc4f39f3f59159baee3302e0f6d9e29 311 Pfam PF02272 DHHA1 domain 175 308 1.6E-9 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 SPSF3K_RS03940 1bbd8608d07a581d23292264f705b7bd 253 SMART SM00448 1 122 2.2E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS03940 1bbd8608d07a581d23292264f705b7bd 253 Gene3D G3DSA:2.40.50.40 138 208 8.6E-8 T 29-03-2018 SPSF3K_RS03940 1bbd8608d07a581d23292264f705b7bd 253 SUPERFAMILY SSF52172 2 132 4.27E-9 T 29-03-2018 IPR011006 CheY-like superfamily SPSF3K_RS03940 1bbd8608d07a581d23292264f705b7bd 253 SMART SM00850 148 239 2.0E-11 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SPSF3K_RS03940 1bbd8608d07a581d23292264f705b7bd 253 Pfam PF04397 LytTr DNA-binding domain 151 237 6.7E-16 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 SPSF3K_RS03940 1bbd8608d07a581d23292264f705b7bd 253 Pfam PF00072 Response regulator receiver domain 16 122 6.1E-10 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 SPSF3K_RS03940 1bbd8608d07a581d23292264f705b7bd 253 Gene3D G3DSA:3.40.50.2300 1 134 8.2E-11 T 29-03-2018 SPSF3K_RS01140 6440c81a79c3a0ea425aaec33e54874b 238 Pfam PF16069 Domain of unknown function (DUF4811) 25 186 4.6E-47 T 29-03-2018 IPR032083 Protein of unknown function DUF4811 SPSF3K_RS04790 ad9ecc4b8a2b6cad058a1d0e7c2ea016 335 Pfam PF01992 ATP synthase (C/AC39) subunit 9 328 2.1E-33 T 29-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04790 ad9ecc4b8a2b6cad058a1d0e7c2ea016 335 SUPERFAMILY SSF103486 6 331 1.7E-43 T 29-03-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04790 ad9ecc4b8a2b6cad058a1d0e7c2ea016 335 Gene3D G3DSA:1.20.1690.10 181 285 7.8E-5 T 29-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS04790 ad9ecc4b8a2b6cad058a1d0e7c2ea016 335 Gene3D G3DSA:1.20.1690.10 80 175 1.1E-12 T 29-03-2018 IPR035067 V-type ATPase subunit c domain Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS00500 065e827be4393555edd231907874fe4a 105 Hamap MF_01448 UPF0473 protein . 14 104 23.127 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 SPSF3K_RS00500 065e827be4393555edd231907874fe4a 105 Pfam PF06949 Protein of unknown function (DUF1292) 23 103 2.1E-15 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 SPSF3K_RS03490 31dd3dd0bbbed2bc5a4735a8ae5367e5 200 Pfam PF02498 BRO family, N-terminal domain 11 93 3.9E-16 T 29-03-2018 IPR003497 BRO N-terminal domain SPSF3K_RS03490 31dd3dd0bbbed2bc5a4735a8ae5367e5 200 SMART SM01040 10 95 1.2E-24 T 29-03-2018 IPR003497 BRO N-terminal domain SPSF3K_RS01510 7f8b29c02ff2eedb4c69d21c6ba502bf 294 Gene3D G3DSA:3.30.420.40 2 116 3.7E-11 T 29-03-2018 SPSF3K_RS01510 7f8b29c02ff2eedb4c69d21c6ba502bf 294 Gene3D G3DSA:3.30.420.40 117 289 7.3E-23 T 29-03-2018 SPSF3K_RS01510 7f8b29c02ff2eedb4c69d21c6ba502bf 294 Pfam PF00480 ROK family 6 288 3.3E-62 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 SPSF3K_RS01510 7f8b29c02ff2eedb4c69d21c6ba502bf 294 SUPERFAMILY SSF53067 6 288 2.02E-33 T 29-03-2018 SPSF3K_RS08470 63c3dd2f103807526a986e64a22b1d19 183 Gene3D G3DSA:3.40.630.30 11 178 8.5E-15 T 29-03-2018 SPSF3K_RS08470 63c3dd2f103807526a986e64a22b1d19 183 SUPERFAMILY SSF55729 12 174 9.04E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS08470 63c3dd2f103807526a986e64a22b1d19 183 Pfam PF13302 Acetyltransferase (GNAT) domain 17 153 1.2E-24 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS02120 499293e1cd15408e7564a74b51afc7c3 222 SUPERFAMILY SSF51569 1 217 1.15E-57 T 29-03-2018 SPSF3K_RS02120 499293e1cd15408e7564a74b51afc7c3 222 Gene3D G3DSA:3.20.20.70 1 222 6.3E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 SPSF3K_RS02120 499293e1cd15408e7564a74b51afc7c3 222 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 4 211 2.2E-40 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SPSF3K_RS02120 499293e1cd15408e7564a74b51afc7c3 222 ProSitePatterns PS00958 Transaldolase active site. 84 101 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 SPSF3K_RS09820 4005f37c1d27f1110b8b24957992f4e2 82 Pfam PF08951 Enterocin A Immunity 5 76 1.8E-12 T 29-03-2018 IPR015046 Enterocin A Immunity SPSF3K_RS09820 4005f37c1d27f1110b8b24957992f4e2 82 SUPERFAMILY SSF109797 1 79 6.02E-18 T 29-03-2018 SPSF3K_RS09820 4005f37c1d27f1110b8b24957992f4e2 82 Gene3D G3DSA:1.20.1440.50 3 81 3.3E-17 T 29-03-2018 IPR023130 Ta0600-like domain SPSF3K_RS09615 f12b2f1a9b85223cef64cabd819749d7 117 SUPERFAMILY SSF50249 1 81 2.75E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold SPSF3K_RS09615 f12b2f1a9b85223cef64cabd819749d7 117 SMART SM00316 2 73 8.0E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 SPSF3K_RS09615 f12b2f1a9b85223cef64cabd819749d7 117 Gene3D G3DSA:2.40.50.140 1 81 2.3E-24 T 29-03-2018 SPSF3K_RS09615 f12b2f1a9b85223cef64cabd819749d7 117 Pfam PF00575 S1 RNA binding domain 2 73 2.4E-16 T 29-03-2018 IPR003029 S1 domain GO:0003676 SPSF3K_RS05100 83c42600aec850801dbab105281e0a1a 167 Pfam PF01476 LysM domain 122 166 9.3E-5 T 29-03-2018 IPR018392 LysM domain SPSF3K_RS05100 83c42600aec850801dbab105281e0a1a 167 SMART SM00257 120 167 0.0021 T 29-03-2018 IPR018392 LysM domain SPSF3K_RS05100 83c42600aec850801dbab105281e0a1a 167 Gene3D G3DSA:3.10.350.10 107 166 6.1E-8 T 29-03-2018 SPSF3K_RS05100 83c42600aec850801dbab105281e0a1a 167 SUPERFAMILY SSF54106 119 152 4.19E-5 T 29-03-2018 IPR018392 LysM domain SPSF3K_RS06560 006d66c9514571c9b0b4899c4661e1ad 86 SUPERFAMILY SSF46689 2 83 1.58E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 SPSF3K_RS06560 006d66c9514571c9b0b4899c4661e1ad 86 Gene3D G3DSA:1.10.10.10 1 74 3.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS06560 006d66c9514571c9b0b4899c4661e1ad 86 Pfam PF01527 Transposase 3 69 4.6E-11 T 29-03-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 SPSF3K_RS06940 fe98ed1b615c2553a58eeeeb0dc812a2 112 Pfam PF03477 ATP cone domain 1 92 5.5E-20 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 SPSF3K_RS05060 4df35db48f080327d47e8a31d1f422e3 825 Pfam PF00884 Sulfatase 482 766 6.7E-37 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SPSF3K_RS05060 4df35db48f080327d47e8a31d1f422e3 825 Gene3D G3DSA:3.40.720.10 475 773 5.6E-10 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SPSF3K_RS05060 4df35db48f080327d47e8a31d1f422e3 825 SUPERFAMILY SSF53649 540 721 3.49E-6 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SPSF3K_RS03810 4697ce69f05b6e733f4cd1840408c355 278 SUPERFAMILY SSF81345 9 262 2.22E-42 T 29-03-2018 IPR029022 ABC transporter, BtuC-like SPSF3K_RS03810 4697ce69f05b6e733f4cd1840408c355 278 Pfam PF00950 ABC 3 transport family 11 266 2.4E-77 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 SPSF3K_RS03810 4697ce69f05b6e733f4cd1840408c355 278 Gene3D G3DSA:1.10.3470.10 8 274 8.4E-32 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like SPSF3K_RS02320 b4af2f24deb1f9015d400104efb27bc5 331 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 34 176 1.2E-5 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SPSF3K_RS02320 b4af2f24deb1f9015d400104efb27bc5 331 SUPERFAMILY SSF53474 254 331 8.75E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS02320 b4af2f24deb1f9015d400104efb27bc5 331 SUPERFAMILY SSF53474 5 221 8.75E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS02320 b4af2f24deb1f9015d400104efb27bc5 331 Gene3D G3DSA:3.40.50.1820 3 330 2.3E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS00830 b539c1e7c1e975305052e5efff08f208 182 PIRSF PIRSF016661 1 175 6.8E-32 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SPSF3K_RS00830 b539c1e7c1e975305052e5efff08f208 182 Pfam PF02632 BioY family 30 170 1.8E-25 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SPSF3K_RS02945 bae42fcdb53905ec2f55aca15e42a33d 307 Pfam PF12146 Serine aminopeptidase, S33 86 187 3.7E-8 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 SPSF3K_RS02945 bae42fcdb53905ec2f55aca15e42a33d 307 Gene3D G3DSA:3.40.50.1820 45 306 2.1E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS02945 bae42fcdb53905ec2f55aca15e42a33d 307 SUPERFAMILY SSF53474 35 306 2.75E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS04070 fb95405c1025a9d41ba3433d6cd589a6 332 Gene3D G3DSA:3.40.50.2000 11 149 1.9E-6 T 29-03-2018 SPSF3K_RS04070 fb95405c1025a9d41ba3433d6cd589a6 332 Pfam PF13439 Glycosyltransferase Family 4 43 139 3.3E-15 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 SPSF3K_RS04070 fb95405c1025a9d41ba3433d6cd589a6 332 Pfam PF00534 Glycosyl transferases group 1 156 274 5.9E-10 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 SPSF3K_RS04070 fb95405c1025a9d41ba3433d6cd589a6 332 Gene3D G3DSA:3.40.50.2000 150 320 3.5E-23 T 29-03-2018 SPSF3K_RS04070 fb95405c1025a9d41ba3433d6cd589a6 332 SUPERFAMILY SSF53756 10 329 1.99E-49 T 29-03-2018 SPSF3K_RS00130 68f07967ffcfe8dd702cc3f3d3cd6b86 125 Pfam PF00293 NUDIX domain 6 114 1.9E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SPSF3K_RS00130 68f07967ffcfe8dd702cc3f3d3cd6b86 125 Gene3D G3DSA:3.90.79.10 1 124 1.4E-13 T 29-03-2018 SPSF3K_RS00130 68f07967ffcfe8dd702cc3f3d3cd6b86 125 SUPERFAMILY SSF55811 6 119 5.69E-16 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPSF3K_RS10180 4267004b975de0e66d38a3a056ff9d1d 78 Pfam PF04226 Transglycosylase associated protein 31 75 4.5E-9 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SPSF3K_RS04250 c8ce8150be03307c5c7ec3063c50a02e 146 Pfam PF10263 SprT-like family 6 96 9.2E-10 T 29-03-2018 IPR006640 SprT-like SPSF3K_RS04250 c8ce8150be03307c5c7ec3063c50a02e 146 SMART SM00731 1 141 8.4E-50 T 29-03-2018 IPR006640 SprT-like SPSF3K_RS05040 9810c3818e77c7c72f35759850613d56 267 Pfam PF01061 ABC-2 type transporter 12 220 2.4E-19 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SPSF3K_RS05245 f1f2b56ff81f83fe3429e4604a105caf 236 SMART SM00382 37 224 1.7E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain SPSF3K_RS05245 f1f2b56ff81f83fe3429e4604a105caf 236 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPSF3K_RS05245 f1f2b56ff81f83fe3429e4604a105caf 236 Gene3D G3DSA:3.40.50.300 4 233 4.1E-65 T 29-03-2018 SPSF3K_RS05245 f1f2b56ff81f83fe3429e4604a105caf 236 SUPERFAMILY SSF52540 8 229 7.92E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPSF3K_RS05245 f1f2b56ff81f83fe3429e4604a105caf 236 Pfam PF00005 ABC transporter 28 176 3.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPSF3K_RS00375 4b4cad7cb7c74a49d9a2b6feee4d820a 144 SUPERFAMILY SSF88659 91 138 2.62E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPSF3K_RS00375 4b4cad7cb7c74a49d9a2b6feee4d820a 144 Gene3D G3DSA:1.10.10.10 52 142 2.7E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain SPSF3K_RS00375 4b4cad7cb7c74a49d9a2b6feee4d820a 144 Pfam PF07374 Protein of unknown function (DUF1492) 39 131 9.4E-6 T 29-03-2018 IPR010861 Protein of unknown function DUF1492 SPSF3K_RS03875 debcf3bcfa861cf6eed099a5eb2e96ac 116 Pfam PF06100 MCRA family 1 116 1.2E-25 T 29-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 SPSF3K_RS05415 6967c4a9101b8e0d620a1e624ee4928f 333 SUPERFAMILY SSF55060 198 329 1.42E-26 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS05415 6967c4a9101b8e0d620a1e624ee4928f 333 Gene3D G3DSA:3.30.230.10 4 197 1.5E-25 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPSF3K_RS05415 6967c4a9101b8e0d620a1e624ee4928f 333 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 5 324 1.5E-58 T 29-03-2018 IPR005917 Phosphomevalonate kinase KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922 SPSF3K_RS05415 6967c4a9101b8e0d620a1e624ee4928f 333 Gene3D G3DSA:3.30.70.890 198 330 1.7E-15 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain SPSF3K_RS05415 6967c4a9101b8e0d620a1e624ee4928f 333 Pfam PF00288 GHMP kinases N terminal domain 103 158 7.4E-9 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 SPSF3K_RS05415 6967c4a9101b8e0d620a1e624ee4928f 333 SUPERFAMILY SSF54211 6 213 6.22E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold SPSF3K_RS07850 a94c566c1d82c74df0a7c34da28321ca 337 Pfam PF03601 Conserved hypothetical protein 698 9 315 7.3E-93 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 SPSF3K_RS05075 6066ec8af21415000b40eef302ea9eb5 146 Pfam PF04138 GtrA-like protein 16 142 5.0E-23 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 SPSF3K_RS06110 716da3c87a05a440b7cb06864b0164ab 159 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 133 4.0E-43 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SPSF3K_RS06110 716da3c87a05a440b7cb06864b0164ab 159 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 133 1.8E-37 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SPSF3K_RS06110 716da3c87a05a440b7cb06864b0164ab 159 SUPERFAMILY SSF55083 1 154 2.49E-49 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SPSF3K_RS06110 716da3c87a05a440b7cb06864b0164ab 159 Gene3D G3DSA:3.30.70.560 1 157 8.6E-55 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 SPSF3K_RS08460 7b03bcf2e41503ab534694075310d3ea 286 SUPERFAMILY SSF55920 129 282 5.41E-60 T 29-03-2018 IPR000994 Peptidase M24 SPSF3K_RS08460 7b03bcf2e41503ab534694075310d3ea 286 SUPERFAMILY SSF55920 4 101 5.41E-60 T 29-03-2018 IPR000994 Peptidase M24 SPSF3K_RS08460 7b03bcf2e41503ab534694075310d3ea 286 Gene3D G3DSA:3.90.230.10 1 281 1.3E-67 T 29-03-2018 SPSF3K_RS08460 7b03bcf2e41503ab534694075310d3ea 286 Hamap MF_01974 Methionine aminopeptidase [map]. 2 280 34.962 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 SPSF3K_RS08460 7b03bcf2e41503ab534694075310d3ea 286 Pfam PF00557 Metallopeptidase family M24 130 271 3.9E-28 T 29-03-2018 IPR000994 Peptidase M24 SPSF3K_RS08460 7b03bcf2e41503ab534694075310d3ea 286 Pfam PF00557 Metallopeptidase family M24 11 99 2.1E-7 T 29-03-2018 IPR000994 Peptidase M24 SPSF3K_RS09980 25861a142488734a5ebd27c19d8c0daf 344 PIRSF PIRSF037259 1 158 3.1E-48 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 SPSF3K_RS09980 25861a142488734a5ebd27c19d8c0daf 344 PIRSF PIRSF037259 147 344 2.9E-56 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 SPSF3K_RS09980 25861a142488734a5ebd27c19d8c0daf 344 Pfam PF05975 Bacterial ABC transporter protein EcsB 158 322 2.7E-40 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 SPSF3K_RS09980 25861a142488734a5ebd27c19d8c0daf 344 Pfam PF05975 Bacterial ABC transporter protein EcsB 3 153 1.8E-37 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 SPSF3K_RS03870 d31a922628aaa428b25caae32ae809c9 114 Pfam PF06100 MCRA family 8 104 3.1E-35 T 29-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 SPSF3K_RS09210 3fa1ae19bff981cc197484d6887067a3 456 PIRSF PIRSF006603 1 452 1.2E-75 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS09210 3fa1ae19bff981cc197484d6887067a3 456 Pfam PF01554 MatE 270 407 1.6E-19 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS09210 3fa1ae19bff981cc197484d6887067a3 456 Pfam PF01554 MatE 21 181 7.3E-20 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 SPSF3K_RS02140 0efbad7af38b4faeb901cfb23013a639 284 SUPERFAMILY SSF161098 11 276 1.68E-63 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS02140 0efbad7af38b4faeb901cfb23013a639 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 272 1.1E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS02140 0efbad7af38b4faeb901cfb23013a639 284 Gene3D G3DSA:1.10.3720.10 3 270 1.6E-42 T 29-03-2018 SPSF3K_RS02080 843be654922f5fc4b5ae75450c3378d6 285 Gene3D G3DSA:3.40.50.2300 70 211 0.16 T 29-03-2018 SPSF3K_RS00870 547a8add05eb1a0c75713a78d6afdfe3 161 Pfam PF06923 Glucitol operon activator protein (GutM) 7 114 3.2E-36 T 29-03-2018 IPR009693 Glucitol operon activator SPSF3K_RS00870 547a8add05eb1a0c75713a78d6afdfe3 161 PIRSF PIRSF011474 2 159 6.6E-52 T 29-03-2018 IPR009693 Glucitol operon activator SPSF3K_RS07375 b8f0550f28ae41c859b0c46efe84ec58 114 Gene3D G3DSA:1.10.3230.10 1 104 4.2E-4 T 29-03-2018 SPSF3K_RS07375 b8f0550f28ae41c859b0c46efe84ec58 114 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 11 98 1.7E-13 T 29-03-2018 IPR006450 Phage protein of unkonwn function SPSF3K_RS07375 b8f0550f28ae41c859b0c46efe84ec58 114 Pfam PF05135 Phage gp6-like head-tail connector protein 4 95 1.3E-11 T 29-03-2018 IPR021146 Phage gp6-like head-tail connector protein SPSF3K_RS01870 4b35c39d3d03ce90a93b9fdcab89d33c 339 PIRSF PIRSF000267 1 337 9.0E-102 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SPSF3K_RS01870 4b35c39d3d03ce90a93b9fdcab89d33c 339 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 222 1.3E-67 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SPSF3K_RS01870 4b35c39d3d03ce90a93b9fdcab89d33c 339 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 325 5.2E-98 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 SPSF3K_RS06445 f4415bf28e138dbafb782b9783d0d06e 237 Pfam PF04474 Protein of unknown function (DUF554) 4 234 1.4E-67 T 29-03-2018 IPR007563 Protein of unknown function DUF554 SPSF3K_RS02220 9382fd32441d4e298367b8801d54e8cc 102 Gene3D G3DSA:2.60.120.260 8 100 1.4E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like SPSF3K_RS00275 8d2acc7de9d2fb52b8767de0191ad091 137 Gene3D G3DSA:1.10.260.40 1 137 9.6E-12 T 29-03-2018 SPSF3K_RS00275 8d2acc7de9d2fb52b8767de0191ad091 137 Pfam PF01381 Helix-turn-helix 1 30 1.0E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPSF3K_RS00275 8d2acc7de9d2fb52b8767de0191ad091 137 SUPERFAMILY SSF47413 1 45 8.96E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS08385 37800d1048ca34f9541ceaa2406f9278 787 Pfam PF02687 FtsX-like permease family 283 374 2.0E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 SPSF3K_RS06710 588da5acd6a082363f0212520b724b36 149 Pfam PF12821 Threonine/Serine exporter, ThrE 6 132 3.6E-32 T 29-03-2018 IPR024528 Threonine/Serine exporter, ThrE SPSF3K_RS07940 95047487bc6daea8a3d7aeb8e59929a0 209 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 1 207 2.1E-45 T 29-03-2018 IPR010178 Integral membrane protein 1906 SPSF3K_RS07940 95047487bc6daea8a3d7aeb8e59929a0 209 Pfam PF07314 Protein of unknown function (DUF1461) 9 180 3.0E-42 T 29-03-2018 IPR010178 Integral membrane protein 1906 SPSF3K_RS00265 5a76c77aa1e5c4e7ad29901f6dc84363 280 Pfam PF04018 Domain of unknown function (DUF368) 19 236 5.6E-32 T 29-03-2018 IPR007163 Protein of unknown function DUF368 SPSF3K_RS01660 d1c5beb37b0dd553a7b46af6d91962e2 153 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 71 106 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SPSF3K_RS01660 d1c5beb37b0dd553a7b46af6d91962e2 153 SUPERFAMILY SSF53927 9 141 2.45E-38 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SPSF3K_RS01660 d1c5beb37b0dd553a7b46af6d91962e2 153 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 116 4.4E-27 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SPSF3K_RS01660 d1c5beb37b0dd553a7b46af6d91962e2 153 Gene3D G3DSA:3.40.140.10 4 149 3.1E-38 T 29-03-2018 SPSF3K_RS01660 d1c5beb37b0dd553a7b46af6d91962e2 153 PIRSF PIRSF006019 1 152 1.3E-54 T 29-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 SPSF3K_RS05480 4b7e81985f2d2794915419a6d935aa1e 284 Pfam PF06970 Replication initiator protein A (RepA) N-terminus 16 96 8.8E-21 T 29-03-2018 IPR010724 Replication initiator A, N-terminal SPSF3K_RS04400 2014147328e58b9fe7caf01efd000577 187 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 8 185 2.3E-61 T 29-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 SPSF3K_RS04400 2014147328e58b9fe7caf01efd000577 187 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 10 183 7.8E-56 T 29-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 SPSF3K_RS09330 a40fd17129bb5d5ca1eb074869de9c24 339 SUPERFAMILY SSF53474 48 313 1.88E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS09330 a40fd17129bb5d5ca1eb074869de9c24 339 Pfam PF07859 alpha/beta hydrolase fold 99 309 6.2E-41 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SPSF3K_RS09330 a40fd17129bb5d5ca1eb074869de9c24 339 Gene3D G3DSA:3.40.50.1820 31 328 1.1E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS07010 b3d80aefc75aef92083f2d937b7a2f0d 129 Gene3D G3DSA:3.40.140.10 3 129 4.2E-46 T 29-03-2018 SPSF3K_RS07010 b3d80aefc75aef92083f2d937b7a2f0d 129 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 97 1.8E-15 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain SPSF3K_RS07010 b3d80aefc75aef92083f2d937b7a2f0d 129 SUPERFAMILY SSF53927 6 126 1.95E-44 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 SPSF3K_RS07010 b3d80aefc75aef92083f2d937b7a2f0d 129 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SPSF3K_RS07010 b3d80aefc75aef92083f2d937b7a2f0d 129 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 6 126 1.5E-43 T 29-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 SPSF3K_RS04765 66ba41fed941313691570ecbf2fa8531 340 Pfam PF13303 Phosphotransferase system, EIIC 29 336 5.2E-63 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS00515 6a780be275181c36ed66405dc9e2d031 320 Gene3D G3DSA:3.30.360.10 133 307 4.3E-12 T 29-03-2018 SPSF3K_RS00515 6a780be275181c36ed66405dc9e2d031 320 SUPERFAMILY SSF51735 1 134 3.94E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain SPSF3K_RS00515 6a780be275181c36ed66405dc9e2d031 320 SUPERFAMILY SSF55347 122 259 4.8E-36 T 29-03-2018 SPSF3K_RS00515 6a780be275181c36ed66405dc9e2d031 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 119 6.0E-15 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 SPSF3K_RS00515 6a780be275181c36ed66405dc9e2d031 320 Gene3D G3DSA:3.40.50.720 1 132 1.1E-25 T 29-03-2018 SPSF3K_RS09340 048496f95fbaa805439b368289e78dbd 408 Pfam PF07690 Major Facilitator Superfamily 13 277 7.3E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPSF3K_RS09340 048496f95fbaa805439b368289e78dbd 408 SUPERFAMILY SSF103473 7 397 1.22E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain SPSF3K_RS09340 048496f95fbaa805439b368289e78dbd 408 Gene3D G3DSA:1.20.1250.20 200 391 2.0E-15 T 29-03-2018 SPSF3K_RS09340 048496f95fbaa805439b368289e78dbd 408 Gene3D G3DSA:1.20.1250.20 3 199 2.1E-27 T 29-03-2018 SPSF3K_RS09340 048496f95fbaa805439b368289e78dbd 408 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 SPSF3K_RS07560 a552aaa38b72b0b230304660d29059e6 207 Pfam PF12978 Domain of Unknown Function with PDB structure (DUF3862) 48 205 1.8E-69 T 29-03-2018 IPR024418 Protein of unknown function DUF3862 SPSF3K_RS07560 a552aaa38b72b0b230304660d29059e6 207 Gene3D G3DSA:3.30.1450.10 48 125 9.0E-7 T 29-03-2018 SPSF3K_RS07560 a552aaa38b72b0b230304660d29059e6 207 Gene3D G3DSA:3.30.1450.10 126 206 4.8E-19 T 29-03-2018 SPSF3K_RS04430 97ace899d8227f5623a6246da5772b86 426 Pfam PF01098 Cell cycle protein 13 394 1.1E-89 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SPSF3K_RS10300 84d88b4b29d9eebc591b4a0f55ccd495 170 Pfam PF02378 Phosphotransferase system, EIIC 11 164 9.6E-18 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS00820 b0b28a8e71dd2fd383a66eab25245e51 380 Pfam PF01702 Queuine tRNA-ribosyltransferase 134 367 3.1E-88 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SPSF3K_RS00820 b0b28a8e71dd2fd383a66eab25245e51 380 Gene3D G3DSA:3.20.20.105 2 376 3.1E-153 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SPSF3K_RS00820 b0b28a8e71dd2fd383a66eab25245e51 380 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 6 370 55.318 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SPSF3K_RS00820 b0b28a8e71dd2fd383a66eab25245e51 380 SUPERFAMILY SSF51713 6 371 2.49E-154 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SPSF3K_RS00820 b0b28a8e71dd2fd383a66eab25245e51 380 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 8 375 1.4E-170 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SPSF3K_RS00820 b0b28a8e71dd2fd383a66eab25245e51 380 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 8 374 5.1E-162 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 SPSF3K_RS06470 67976a0e0f423be88b72e4846a84f8ac 263 Pfam PF03747 ADP-ribosylglycohydrolase 1 233 1.4E-38 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SPSF3K_RS06470 67976a0e0f423be88b72e4846a84f8ac 263 SUPERFAMILY SSF101478 1 243 3.14E-55 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SPSF3K_RS06470 67976a0e0f423be88b72e4846a84f8ac 263 Gene3D G3DSA:1.10.4080.10 1 255 2.3E-51 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 SPSF3K_RS09005 2507ad42551e2f762f97bcec77f2ba49 322 Gene3D G3DSA:3.40.50.2300 42 160 5.5E-29 T 29-03-2018 SPSF3K_RS09005 2507ad42551e2f762f97bcec77f2ba49 322 Gene3D G3DSA:3.40.50.2300 161 309 1.1E-38 T 29-03-2018 SPSF3K_RS09005 2507ad42551e2f762f97bcec77f2ba49 322 SUPERFAMILY SSF53822 45 320 8.46E-87 T 29-03-2018 IPR028082 Periplasmic binding protein-like I SPSF3K_RS09005 2507ad42551e2f762f97bcec77f2ba49 322 Pfam PF13407 Periplasmic binding protein domain 50 300 7.9E-62 T 29-03-2018 IPR025997 Periplasmic binding protein SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 Gene3D G3DSA:1.20.58.180 210 286 2.3E-34 T 29-03-2018 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 6 291 7.6E-154 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 5 285 57.617 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 7 283 5.3E-145 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 245 261 8.2E-65 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 80 100 8.2E-65 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 160 175 8.2E-65 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 111 135 8.2E-65 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 137 157 8.2E-65 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 59 74 8.2E-65 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 Gene3D G3DSA:3.30.930.10 1 208 5.3E-83 T 29-03-2018 SPSF3K_RS09880 a80a9f293d9b9b7b49da0e04b7054596 305 SUPERFAMILY SSF55681 6 284 1.12E-128 T 29-03-2018 SPSF3K_RS07500 e8c9b4acaf3e4112908bd2f7ebc97103 114 Gene3D G3DSA:1.10.10.60 1 44 5.9E-6 T 29-03-2018 SPSF3K_RS07150 64ab23cd030f8062e3cb81521040c3f5 157 Pfam PF03780 Asp23 family, cell envelope-related function 3 108 2.5E-31 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 SPSF3K_RS08415 f76ed9f1d4fac3dee49a3a264cdf13b7 165 Pfam PF11193 Protein of unknown function (DUF2812) 2 104 2.4E-24 T 29-03-2018 IPR021359 Protein of unknown function DUF2812 SPSF3K_RS09290 9027039677e033225d6c051a1846e17a 153 SUPERFAMILY SSF55826 2 150 1.7E-27 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS09290 9027039677e033225d6c051a1846e17a 153 Pfam PF04073 Aminoacyl-tRNA editing domain 30 141 7.1E-18 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS09290 9027039677e033225d6c051a1846e17a 153 Gene3D G3DSA:3.90.960.10 1 146 1.8E-19 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPSF3K_RS02010 a469905747f03eab68f0e47c013c02c7 105 Pfam PF00085 Thioredoxin 12 102 7.2E-18 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SPSF3K_RS02010 a469905747f03eab68f0e47c013c02c7 105 SUPERFAMILY SSF52833 3 102 2.79E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS02010 a469905747f03eab68f0e47c013c02c7 105 Gene3D G3DSA:3.40.30.10 3 105 1.2E-20 T 29-03-2018 SPSF3K_RS02980 dbb427210c1cbff3a4ea39bc43df441d 296 SUPERFAMILY SSF117892 56 187 8.24E-26 T 29-03-2018 IPR001107 Band 7 domain SPSF3K_RS02980 dbb427210c1cbff3a4ea39bc43df441d 296 SMART SM00244 21 181 4.2E-29 T 29-03-2018 IPR001107 Band 7 domain SPSF3K_RS02980 dbb427210c1cbff3a4ea39bc43df441d 296 Pfam PF01145 SPFH domain / Band 7 family 25 197 9.6E-29 T 29-03-2018 IPR001107 Band 7 domain SPSF3K_RS01040 b9f16e4033690df63ab27ff1a96a13fc 155 Gene3D G3DSA:3.30.530.20 7 86 5.0E-4 T 29-03-2018 IPR023393 START-like domain SPSF3K_RS01040 b9f16e4033690df63ab27ff1a96a13fc 155 SUPERFAMILY SSF55961 4 141 2.31E-7 T 29-03-2018 SPSF3K_RS03825 de7acddd3490bd914bdfac1fb0307fcf 116 Pfam PF11877 Protein of unknown function (DUF3397) 6 114 5.0E-24 T 29-03-2018 IPR024515 Protein of unknown function DUF3397 SPSF3K_RS07680 862f60ff633fe5e0c7cf168b2c8aed08 474 Pfam PF01943 Polysaccharide biosynthesis protein 7 281 2.4E-18 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 SPSF3K_RS06025 d1338175cf1ddc8e0bf848880468256c 399 Pfam PF13102 Phage integrase SAM-like domain 87 168 1.0E-6 T 29-03-2018 IPR025269 Phage integrase SAM-like domain SPSF3K_RS06025 d1338175cf1ddc8e0bf848880468256c 399 Gene3D G3DSA:1.10.150.130 73 186 5.2E-16 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal SPSF3K_RS06025 d1338175cf1ddc8e0bf848880468256c 399 SUPERFAMILY SSF56349 78 367 3.24E-51 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPSF3K_RS06025 d1338175cf1ddc8e0bf848880468256c 399 Gene3D G3DSA:1.10.443.10 187 374 2.5E-29 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS06025 d1338175cf1ddc8e0bf848880468256c 399 Pfam PF00589 Phage integrase family 208 365 3.9E-21 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPSF3K_RS06840 3164d14cd663b69fa0dc4d147c816489 222 Pfam PF16264 SatD family (SatD) 3 212 1.4E-96 T 29-03-2018 IPR032580 SatD family SPSF3K_RS09145 e86fb9eac158656cea74eef04bfd2c0b 96 Pfam PF07006 Protein of unknown function (DUF1310) 1 92 1.6E-16 T 29-03-2018 IPR010738 Protein of unknown function DUF1310 SPSF3K_RS09145 e86fb9eac158656cea74eef04bfd2c0b 96 Gene3D G3DSA:3.10.450.130 5 96 4.1E-13 T 29-03-2018 SPSF3K_RS00045 688a6a85878d7b8e557962472440afe3 290 PIRSF PIRSF006483 1 278 1.0E-73 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT SPSF3K_RS00045 688a6a85878d7b8e557962472440afe3 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 210 1.6E-53 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT SPSF3K_RS00045 688a6a85878d7b8e557962472440afe3 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 1.3E-14 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 SPSF3K_RS06835 ce5862544b577df4cdbabd369c083c7f 237 Pfam PF11750 Protein of unknown function (DUF3307) 14 126 8.8E-20 T 29-03-2018 IPR021737 Bacteriophage phiKZ, Orf197 SPSF3K_RS02935 36180e1cfb4698ab1a7aeece16d7e571 143 Pfam PF03788 LrgA family 19 110 1.5E-25 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 SPSF3K_RS02200 4d963101b532123dbf0d94b3a8eb5844 418 Gene3D G3DSA:3.40.190.10 165 418 1.1E-26 T 29-03-2018 SPSF3K_RS02200 4d963101b532123dbf0d94b3a8eb5844 418 Pfam PF13416 Bacterial extracellular solute-binding protein 58 359 6.6E-32 T 29-03-2018 SPSF3K_RS02200 4d963101b532123dbf0d94b3a8eb5844 418 SUPERFAMILY SSF53850 36 416 3.11E-55 T 29-03-2018 SPSF3K_RS02200 4d963101b532123dbf0d94b3a8eb5844 418 Gene3D G3DSA:3.40.190.10 38 164 5.0E-22 T 29-03-2018 SPSF3K_RS04840 9ead87e96ed25fcce8ce5ed9f94b2f65 340 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 5 298 3.0E-75 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase SPSF3K_RS04840 9ead87e96ed25fcce8ce5ed9f94b2f65 340 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 131 7.2E-32 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPSF3K_RS04840 9ead87e96ed25fcce8ce5ed9f94b2f65 340 SUPERFAMILY SSF111331 4 302 4.58E-72 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain SPSF3K_RS04840 9ead87e96ed25fcce8ce5ed9f94b2f65 340 Gene3D G3DSA:3.40.50.10330 1 136 3.4E-28 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 SPSF3K_RS04840 9ead87e96ed25fcce8ce5ed9f94b2f65 340 SMART SM00046 6 130 7.2E-5 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPSF3K_RS03115 8923e9f807c871354e7b99c882782408 159 Gene3D G3DSA:1.10.1740.10 1 75 1.4E-7 T 29-03-2018 SPSF3K_RS07325 8817d357236a917cad9d21f083a93081 106 Gene3D G3DSA:1.20.5.730 26 106 1.1E-4 T 29-03-2018 SPSF3K_RS07155 f0e1bc5cd5cb544e7b4fca46fcf2f928 65 Gene3D G3DSA:1.10.1470.10 1 65 3.3E-15 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS07155 f0e1bc5cd5cb544e7b4fca46fcf2f928 65 SUPERFAMILY SSF69047 1 58 3.01E-12 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS07155 f0e1bc5cd5cb544e7b4fca46fcf2f928 65 Pfam PF05532 CsbD-like 4 55 8.0E-16 T 29-03-2018 IPR008462 CsbD-like domain SPSF3K_RS00380 5f0d6d48315b86787459331b885935b4 139 Pfam PF07374 Protein of unknown function (DUF1492) 33 131 6.5E-11 T 29-03-2018 IPR010861 Protein of unknown function DUF1492 SPSF3K_RS07740 d5e00106030322024dc7a0f3bf7a6ca4 243 SUPERFAMILY SSF51556 1 237 9.52E-19 T 29-03-2018 IPR032466 Metal-dependent hydrolase SPSF3K_RS07740 d5e00106030322024dc7a0f3bf7a6ca4 243 PIRSF PIRSF016557 1 243 1.8E-82 T 29-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 SPSF3K_RS07740 d5e00106030322024dc7a0f3bf7a6ca4 243 Gene3D G3DSA:3.20.20.140 1 241 2.4E-23 T 29-03-2018 SPSF3K_RS09745 8234696cf05fc7a7d3e88566ba3f20c4 460 ProSitePatterns PS00218 Amino acid permeases signature. 49 79 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SPSF3K_RS09745 8234696cf05fc7a7d3e88566ba3f20c4 460 Pfam PF00324 Amino acid permease 24 444 1.2E-82 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SPSF3K_RS09745 8234696cf05fc7a7d3e88566ba3f20c4 460 PIRSF PIRSF006060 1 456 2.0E-55 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPSF3K_RS06150 76da98c3600272add7bd8ffe33e630de 445 TIGRFAM TIGR00783 ccs: citrate carrier protein, CCS family 21 437 2.0E-170 T 29-03-2018 IPR018025 2-hydroxycarboxylate transporter, Proteobacteria/Firmicutes SPSF3K_RS06150 76da98c3600272add7bd8ffe33e630de 445 Pfam PF03390 2-hydroxycarboxylate transporter family 26 436 1.3E-152 T 29-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 SPSF3K_RS06150 76da98c3600272add7bd8ffe33e630de 445 PIRSF PIRSF005348 5 443 4.4E-165 T 29-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 SPSF3K_RS01330 1413b0a75fd2ca3385d7d3ee51cfe5f4 324 Pfam PF00294 pfkB family carbohydrate kinase 1 305 1.5E-52 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB SPSF3K_RS01330 1413b0a75fd2ca3385d7d3ee51cfe5f4 324 Gene3D G3DSA:3.40.1190.20 2 317 3.4E-60 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS01330 1413b0a75fd2ca3385d7d3ee51cfe5f4 324 SUPERFAMILY SSF53613 1 312 2.96E-77 T 29-03-2018 IPR029056 Ribokinase-like SPSF3K_RS01330 1413b0a75fd2ca3385d7d3ee51cfe5f4 324 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 257 270 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 342 364 2.4E-6 T 29-03-2018 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.4E-6 T 29-03-2018 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.4E-6 T 29-03-2018 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 SUPERFAMILY SSF51905 1 191 1.44E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 SUPERFAMILY SSF51905 332 386 1.44E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 Gene3D G3DSA:3.50.50.60 6 388 5.8E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 387 8.4E-129 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 167 4.9E-6 T 29-03-2018 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.9E-6 T 29-03-2018 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 SUPERFAMILY SSF160996 193 335 4.71E-30 T 29-03-2018 SPSF3K_RS01285 cd755cd2e5780ee8edb9ddfc453b47f9 390 Pfam PF03486 HI0933-like protein 5 387 6.4E-138 T 29-03-2018 SPSF3K_RS01185 e94572e2bc77513894eae4564671e893 926 Gene3D G3DSA:1.10.287.620 45 199 5.7E-4 T 29-03-2018 SPSF3K_RS01185 e94572e2bc77513894eae4564671e893 926 Gene3D G3DSA:1.10.287.620 520 669 4.3E-5 T 29-03-2018 SPSF3K_RS01185 e94572e2bc77513894eae4564671e893 926 SUPERFAMILY SSF57997 535 696 9.15E-6 T 29-03-2018 SPSF3K_RS01185 e94572e2bc77513894eae4564671e893 926 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 246 631 5.4E-84 T 29-03-2018 IPR027607 SEC10/PgrA surface exclusion domain SPSF3K_RS00835 c2f849b563b8c6ee3609a58b0f594d19 259 SMART SM00849 18 213 1.0E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS00835 c2f849b563b8c6ee3609a58b0f594d19 259 Gene3D G3DSA:3.60.15.10 1 257 6.8E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS00835 c2f849b563b8c6ee3609a58b0f594d19 259 SUPERFAMILY SSF56281 1 233 2.62E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS00835 c2f849b563b8c6ee3609a58b0f594d19 259 Pfam PF12706 Beta-lactamase superfamily domain 37 214 7.1E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase SPSF3K_RS02775 18289ac631ad035597d774e259f1aa40 184 SUPERFAMILY SSF55729 10 179 1.15E-45 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS02775 18289ac631ad035597d774e259f1aa40 184 Gene3D G3DSA:3.40.630.30 7 183 1.1E-28 T 29-03-2018 SPSF3K_RS02775 18289ac631ad035597d774e259f1aa40 184 Pfam PF13302 Acetyltransferase (GNAT) domain 15 155 1.2E-31 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS04355 d972ed8f30db4925588b2c80796ef3c5 445 PIRSF PIRSF006060 1 443 2.8E-65 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPSF3K_RS04355 d972ed8f30db4925588b2c80796ef3c5 445 Pfam PF13520 Amino acid permease 16 407 2.2E-45 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPSF3K_RS04775 9d447ed901a0364247b153f9fd4a9246 666 Pfam PF01496 V-type ATPase 116kDa subunit family 239 419 1.9E-10 T 29-03-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 SPSF3K_RS03945 221b33104db0d5eea9e089b0162ba7a0 95 Pfam PF08951 Enterocin A Immunity 15 85 1.2E-7 T 29-03-2018 IPR015046 Enterocin A Immunity SPSF3K_RS03945 221b33104db0d5eea9e089b0162ba7a0 95 Gene3D G3DSA:1.20.1440.50 11 94 1.4E-5 T 29-03-2018 IPR023130 Ta0600-like domain SPSF3K_RS08440 4ab7f3eb21f86af5475bec5afb5b3a89 523 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 265 441 2.8E-26 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SPSF3K_RS08440 4ab7f3eb21f86af5475bec5afb5b3a89 523 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 266 442 7.8E-50 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain SPSF3K_RS04280 7ab9fdff33d45aa8668f0c33c963a4ff 94 Pfam PF11674 Protein of unknown function (DUF3270) 4 88 7.2E-30 T 29-03-2018 IPR021688 Protein of unknown function DUF3270 SPSF3K_RS00105 4d02bb976ddddb96954d0dff7dc05fb1 218 SUPERFAMILY SSF53955 147 203 2.16E-10 T 29-03-2018 IPR023346 Lysozyme-like domain SPSF3K_RS00105 4d02bb976ddddb96954d0dff7dc05fb1 218 Gene3D G3DSA:1.10.530.10 95 212 1.9E-14 T 29-03-2018 SPSF3K_RS00105 4d02bb976ddddb96954d0dff7dc05fb1 218 Pfam PF01464 Transglycosylase SLT domain 149 190 3.9E-6 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 SPSF3K_RS01325 baf501f5d4ad08612a0fb152c9091700 251 SUPERFAMILY SSF51658 4 248 4.97E-41 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SPSF3K_RS01325 baf501f5d4ad08612a0fb152c9091700 251 Pfam PF01261 Xylose isomerase-like TIM barrel 27 194 1.2E-9 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain SPSF3K_RS01325 baf501f5d4ad08612a0fb152c9091700 251 Gene3D G3DSA:3.20.20.150 1 251 3.3E-23 T 29-03-2018 SPSF3K_RS06800 a5b310c072e80d42dadb2da4fba8797c 192 SUPERFAMILY SSF55811 3 160 2.03E-33 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPSF3K_RS06800 a5b310c072e80d42dadb2da4fba8797c 192 ProSitePatterns PS00893 Nudix box signature. 67 88 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPSF3K_RS06800 a5b310c072e80d42dadb2da4fba8797c 192 Gene3D G3DSA:3.90.79.10 1 161 3.7E-28 T 29-03-2018 SPSF3K_RS06800 a5b310c072e80d42dadb2da4fba8797c 192 Pfam PF00293 NUDIX domain 30 145 2.2E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 SPSF3K_RS09860 615ac0c2a569ecb5ea8dca75e8b10107 35 Pfam PF03413 Peptidase propeptide and YPEB domain 2 28 2.5E-5 T 29-03-2018 IPR025711 PepSY domain SPSF3K_RS09860 615ac0c2a569ecb5ea8dca75e8b10107 35 Gene3D G3DSA:3.10.450.40 1 31 1.2E-7 T 29-03-2018 SPSF3K_RS01085 6cd14f2e5c3fe708215ad594fbd530cf 454 SUPERFAMILY SSF53850 20 442 4.68E-68 T 29-03-2018 SPSF3K_RS01085 6cd14f2e5c3fe708215ad594fbd530cf 454 Pfam PF01547 Bacterial extracellular solute-binding protein 61 358 1.5E-31 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SPSF3K_RS01085 6cd14f2e5c3fe708215ad594fbd530cf 454 Gene3D G3DSA:3.40.190.10 163 451 8.2E-42 T 29-03-2018 SPSF3K_RS08135 5e25a7e13ec904bdd038a497dbe75339 226 SUPERFAMILY SSF158499 126 190 9.81E-18 T 29-03-2018 IPR006343 DnaD domain SPSF3K_RS08135 5e25a7e13ec904bdd038a497dbe75339 226 Gene3D G3DSA:1.10.10.630 120 197 2.4E-24 T 29-03-2018 IPR034829 DnaD-like domain SPSF3K_RS08135 5e25a7e13ec904bdd038a497dbe75339 226 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 125 197 7.3E-25 T 29-03-2018 IPR006343 DnaD domain SPSF3K_RS08135 5e25a7e13ec904bdd038a497dbe75339 226 Pfam PF07261 Replication initiation and membrane attachment 127 198 1.2E-22 T 29-03-2018 IPR006343 DnaD domain SPSF3K_RS03045 6b672894a9a6cb762aacaa1517240fbf 391 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 48 293 1.3E-42 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SPSF3K_RS03045 6b672894a9a6cb762aacaa1517240fbf 391 SUPERFAMILY SSF56601 3 319 5.37E-63 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like SPSF3K_RS03045 6b672894a9a6cb762aacaa1517240fbf 391 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 157 170 4.8E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPSF3K_RS03045 6b672894a9a6cb762aacaa1517240fbf 391 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 129 146 4.8E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPSF3K_RS03045 6b672894a9a6cb762aacaa1517240fbf 391 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 4.8E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPSF3K_RS03045 6b672894a9a6cb762aacaa1517240fbf 391 Gene3D G3DSA:3.40.710.10 37 319 2.0E-38 T 29-03-2018 SPSF3K_RS04270 494710d99b54d67d1bcc0729e279150b 135 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 93 4.5E-29 T 29-03-2018 IPR009293 Uncharacterised protein family UPF0478 SPSF3K_RS07755 3e83b07d9267245fd2c3a81e7b8af6a1 258 Pfam PF09659 CRISPR-associated protein (Cas_Csm6) 6 251 1.0E-24 T 29-03-2018 IPR013489 CRISPR-associated protein Csm6 SPSF3K_RS08205 2e84ce4d38ca1b5479cf6683295f51c6 88 Gene3D G3DSA:3.20.20.140 2 88 3.3E-4 T 29-03-2018 SPSF3K_RS08205 2e84ce4d38ca1b5479cf6683295f51c6 88 SUPERFAMILY SSF89550 2 85 2.75E-9 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 SPSF3K_RS07960 faffe0741679c8e07709b522451ee13b 218 Pfam PF00583 Acetyltransferase (GNAT) family 108 190 8.7E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS07960 faffe0741679c8e07709b522451ee13b 218 SUPERFAMILY SSF55729 64 210 1.69E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS07960 faffe0741679c8e07709b522451ee13b 218 Gene3D G3DSA:3.40.630.30 62 218 1.1E-15 T 29-03-2018 SPSF3K_RS05055 4d0abba5cfd73aaf3cfacaae4a237ee5 582 Pfam PF05045 Rhamnan synthesis protein F 34 514 5.8E-166 T 29-03-2018 IPR007739 Rhamnan synthesis F SPSF3K_RS09140 1cd5ad77822649e51cc1701b9b79793a 406 Gene3D G3DSA:3.40.50.1820 5 364 2.7E-14 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS09140 1cd5ad77822649e51cc1701b9b79793a 406 Pfam PF11187 Protein of unknown function (DUF2974) 112 242 4.1E-9 T 29-03-2018 IPR024499 Protein of unknown function DUF2974 SPSF3K_RS09140 1cd5ad77822649e51cc1701b9b79793a 406 SUPERFAMILY SSF53474 16 202 4.06E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold SPSF3K_RS08110 5a2d24e916b704dc4fd736e6f6eadd1e 273 Pfam PF02535 ZIP Zinc transporter 123 268 6.1E-16 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 SPSF3K_RS06245 5a414defb544cbf95267a496ef8570b8 70 Pfam PF15507 Domain of unknown function (DUF4649) 2 67 2.1E-25 T 29-03-2018 IPR027879 Protein of unknown function DUF4649 SPSF3K_RS07645 0c980aa5ff3a18fb2183329cb0a8cfc1 252 Pfam PF13508 Acetyltransferase (GNAT) domain 159 234 1.5E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS07645 0c980aa5ff3a18fb2183329cb0a8cfc1 252 Gene3D G3DSA:3.40.630.30 16 252 1.3E-15 T 29-03-2018 SPSF3K_RS07645 0c980aa5ff3a18fb2183329cb0a8cfc1 252 SUPERFAMILY SSF55729 76 238 4.05E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS03220 1ec364f9968c59401be53f3c9163de6f 185 Pfam PF04011 LemA family 6 183 3.3E-70 T 29-03-2018 IPR007156 LemA SPSF3K_RS03220 1ec364f9968c59401be53f3c9163de6f 185 SUPERFAMILY SSF140478 25 173 1.57E-55 T 29-03-2018 IPR023353 LemA-like domain SPSF3K_RS03220 1ec364f9968c59401be53f3c9163de6f 185 Gene3D G3DSA:1.20.1440.20 13 183 1.6E-59 T 29-03-2018 SPSF3K_RS01270 ade885fc4dba014ad703fa36f64b3910 138 SUPERFAMILY SSF55729 4 134 1.86E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase SPSF3K_RS01270 ade885fc4dba014ad703fa36f64b3910 138 Gene3D G3DSA:3.40.630.30 2 138 1.4E-29 T 29-03-2018 SPSF3K_RS01270 ade885fc4dba014ad703fa36f64b3910 138 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 4 130 3.5E-39 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 SPSF3K_RS01270 ade885fc4dba014ad703fa36f64b3910 138 Pfam PF00583 Acetyltransferase (GNAT) family 8 110 3.0E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 SPSF3K_RS07390 425a950a7a4a7a73ae68b598ad462fd6 372 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 38 326 1.7E-43 T 29-03-2018 IPR006427 Phage portal protein, HK97 SPSF3K_RS07390 425a950a7a4a7a73ae68b598ad462fd6 372 Pfam PF04860 Phage portal protein 47 321 1.1E-37 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein SPSF3K_RS08880 6d7e0d14844a591da19216b5a013f370 102 Gene3D G3DSA:3.40.1720.10 1 96 8.9E-38 T 29-03-2018 SPSF3K_RS08880 6d7e0d14844a591da19216b5a013f370 102 Pfam PF08860 Domain of unknown function (DUF1827) 1 97 6.5E-36 T 29-03-2018 IPR014959 Protein of unknown function DUF1827 SPSF3K_RS10030 1e43baf51347d214b733d5cf2627ad0c 270 Pfam PF03609 PTS system sorbose-specific iic component 6 241 8.5E-68 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 SPSF3K_RS03315 66b6d8ed564ff69a685ca4baa5b4fd95 229 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 15 225 9.8E-55 T 29-03-2018 IPR006214 Bax inhibitor 1-related SPSF3K_RS04310 3478754e75cbd7c9cbfee807fa5ca18e 344 Gene3D G3DSA:2.10.270.10 75 329 0.0015 T 29-03-2018 SPSF3K_RS04310 3478754e75cbd7c9cbfee807fa5ca18e 344 Pfam PF06224 Winged helix DNA-binding domain 70 325 2.5E-17 T 29-03-2018 IPR009351 Protein of unknown function DUF1006 SPSF3K_RS02575 037a3719c8d3da02d596495ee81858c7 269 Pfam PF06161 Protein of unknown function (DUF975) 1 139 1.4E-10 T 29-03-2018 IPR010380 Protein of unknown function DUF975 SPSF3K_RS02575 037a3719c8d3da02d596495ee81858c7 269 Pfam PF06161 Protein of unknown function (DUF975) 132 223 4.5E-27 T 29-03-2018 IPR010380 Protein of unknown function DUF975 SPSF3K_RS00900 c8ebbfd2d66689bae43a161e4e16d8fd 418 SUPERFAMILY SSF53448 64 330 2.5E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS00900 c8ebbfd2d66689bae43a161e4e16d8fd 418 Pfam PF00535 Glycosyl transferase family 2 69 237 2.8E-32 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 SPSF3K_RS00900 c8ebbfd2d66689bae43a161e4e16d8fd 418 Gene3D G3DSA:3.90.550.10 66 313 3.2E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases SPSF3K_RS00215 40cd5767ce8f34f33582b49f770d2358 334 Pfam PF03773 Predicted permease 40 327 2.8E-61 T 29-03-2018 IPR005524 Predicted permease DUF318 SPSF3K_RS02655 01a5e21a9dabd625e83ef1be471860d2 144 Gene3D G3DSA:2.60.40.10 23 142 1.5E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold SPSF3K_RS00645 8460d4684e64ee25db37e0829f4550a1 690 Pfam PF00999 Sodium/hydrogen exchanger family 6 402 1.2E-45 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 SPSF3K_RS09755 1df83b1d5974fccbccb28ed589d33ee7 74 Pfam PF13268 Protein of unknown function (DUF4059) 1 72 1.1E-29 T 29-03-2018 IPR025134 Protein of unknown function DUF4059 SPSF3K_RS09885 e96611132c162f982cc55dbd51460a0a 175 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 75 163 4.1E-26 T 29-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 SPSF3K_RS01090 aa3c05a1605ab6f51b52cea6e06e1804 150 Pfam PF04074 Domain of unknown function (DUF386) 1 147 1.6E-35 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family SPSF3K_RS01090 aa3c05a1605ab6f51b52cea6e06e1804 150 Gene3D G3DSA:2.60.120.370 1 150 3.9E-38 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family SPSF3K_RS01090 aa3c05a1605ab6f51b52cea6e06e1804 150 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 150 5.6E-34 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family SPSF3K_RS01090 aa3c05a1605ab6f51b52cea6e06e1804 150 SUPERFAMILY SSF51197 1 149 3.3E-34 T 29-03-2018 SPSF3K_RS01000 6dc43512ad2b511f011c564473646433 408 Gene3D G3DSA:3.30.565.10 178 403 9.1E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS01000 6dc43512ad2b511f011c564473646433 408 SUPERFAMILY SSF55874 268 403 5.38E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPSF3K_RS01000 6dc43512ad2b511f011c564473646433 408 Pfam PF14501 GHKL domain 300 401 1.6E-12 T 29-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain SPSF3K_RS06430 79fca13567f25eede6986911589c245a 324 Pfam PF06207 Protein of unknown function (DUF1002) 47 275 7.4E-55 T 29-03-2018 IPR009343 Protein of unknown function DUF1002 SPSF3K_RS03015 ecbf5f8c315ac18f96032cf87ae86118 385 Pfam PF00953 Glycosyl transferase family 4 90 247 3.2E-38 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 SPSF3K_RS03015 ecbf5f8c315ac18f96032cf87ae86118 385 ProSitePatterns PS01348 MraY family signature 2. 165 176 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 SPSF3K_RS09230 369471483fd13e5231b09e099f00488d 67 Gene3D G3DSA:3.10.310.10 3 55 7.3E-9 T 29-03-2018 SPSF3K_RS09230 369471483fd13e5231b09e099f00488d 67 SUPERFAMILY SSF54506 9 67 4.32E-13 T 29-03-2018 SPSF3K_RS10035 2d82be021df9d43a3fd0e4b59a8d366b 303 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 6 303 1.2E-115 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 SPSF3K_RS04475 4c62c49de847f527bed4c98654a0cdfd 202 SUPERFAMILY SSF161111 2 112 4.84E-7 T 29-03-2018 SPSF3K_RS04475 4c62c49de847f527bed4c98654a0cdfd 202 Gene3D G3DSA:1.20.1510.10 1 111 3.8E-8 T 29-03-2018 SPSF3K_RS06905 6c057f8d021e8a1219a794b9d98aec4c 152 Pfam PF08876 Domain of unknown function (DUF1836) 7 106 1.1E-31 T 29-03-2018 IPR014975 Protein of unknown function DUF1836 SPSF3K_RS06905 6c057f8d021e8a1219a794b9d98aec4c 152 Gene3D G3DSA:1.10.1660.10 25 145 7.2E-4 T 29-03-2018 SPSF3K_RS04020 afb70701e0622a7f3d37cb1853c4432b 104 SUPERFAMILY SSF52794 1 89 9.42E-18 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS04020 afb70701e0622a7f3d37cb1853c4432b 104 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 101 3.3E-16 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPSF3K_RS04020 afb70701e0622a7f3d37cb1853c4432b 104 Gene3D G3DSA:3.40.50.2300 2 104 1.7E-19 T 29-03-2018 SPSF3K_RS08545 fc2b5ddb0574f3d55642f2091adf9312 73 Gene3D G3DSA:3.40.30.10 1 72 1.7E-15 T 29-03-2018 SPSF3K_RS08545 fc2b5ddb0574f3d55642f2091adf9312 73 Pfam PF00462 Glutaredoxin 2 54 1.6E-13 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SPSF3K_RS08545 fc2b5ddb0574f3d55642f2091adf9312 73 SUPERFAMILY SSF52833 1 72 7.88E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS08545 fc2b5ddb0574f3d55642f2091adf9312 73 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 2 72 4.0E-35 T 29-03-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 SPSF3K_RS02250 200b1fa828776275f306a42c299cec40 304 Pfam PF02517 CAAX protease self-immunity 148 239 8.2E-16 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 SPSF3K_RS04615 1ed74dfcf25d952d289c39fe50129eb7 295 Pfam PF03609 PTS system sorbose-specific iic component 4 263 1.3E-61 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 SPSF3K_RS10565 882c84b0866b1582eeb9847bcd3fd7f4 305 SUPERFAMILY SSF47413 3 65 1.81E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPSF3K_RS10565 882c84b0866b1582eeb9847bcd3fd7f4 305 Gene3D G3DSA:1.10.260.40 1 160 5.4E-10 T 29-03-2018 SPSF3K_RS09125 2a756954695430f185c468088bc334eb 115 Gene3D G3DSA:1.25.40.10 3 112 1.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS09125 2a756954695430f185c468088bc334eb 115 SUPERFAMILY SSF48452 8 101 2.17E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPSF3K_RS01500 74e32f961a7b168a7fa7a0c5ddaaf8c3 536 Pfam PF01547 Bacterial extracellular solute-binding protein 65 370 1.3E-14 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 SPSF3K_RS01500 74e32f961a7b168a7fa7a0c5ddaaf8c3 536 Gene3D G3DSA:3.40.190.10 179 534 1.1E-47 T 29-03-2018 SPSF3K_RS01500 74e32f961a7b168a7fa7a0c5ddaaf8c3 536 SUPERFAMILY SSF53850 21 532 2.62E-87 T 29-03-2018 SPSF3K_RS08785 fa48a48d6972e7ab72991be30938a418 208 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 18 203 5.9E-60 T 29-03-2018 IPR018672 Protein of unknown function DUF2140 SPSF3K_RS04690 6d90473903c7bfd24411551d261d2e95 404 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 343 367 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 SPSF3K_RS04690 6d90473903c7bfd24411551d261d2e95 404 Pfam PF01098 Cell cycle protein 20 383 2.9E-73 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 SPSF3K_RS07395 03711f2a3a45896c39d243079f80b9fe 61 Pfam PF06341 Protein of unknown function (DUF1056) 1 59 2.1E-15 T 29-03-2018 IPR009406 Protein of unknown function DUF1056 SPSF3K_RS06530 129aadff2dbb1173cf133aff481c82a8 126 Pfam PF06125 Bacterial protein of unknown function (DUF961) 6 106 2.5E-36 T 29-03-2018 IPR010365 Protein of unknown function DUF961 SPSF3K_RS00080 9f8951ef14b44c1c8cf2e6324aca1da7 325 Pfam PF13413 Helix-turn-helix domain 10 65 8.0E-10 T 29-03-2018 SPSF3K_RS00080 9f8951ef14b44c1c8cf2e6324aca1da7 325 Gene3D G3DSA:1.10.260.40 3 84 1.5E-5 T 29-03-2018 SPSF3K_RS05255 8cc132de88cd749eddaa5468edfa1c9a 203 Pfam PF09335 SNARE associated Golgi protein 74 190 4.4E-18 T 29-03-2018 IPR032816 SNARE associated Golgi protein SPSF3K_RS01050 c2bb9285041509a08d6fb80df8cb2a7e 284 Pfam PF01061 ABC-2 type transporter 3 222 2.2E-9 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 SPSF3K_RS01060 bdd46df65dd2536d4cac02b5b91cbb60 131 Pfam PF11457 Protein of unknown function (DUF3021) 1 123 7.2E-23 T 29-03-2018 IPR021560 Protein of unknown function DUF3021 SPSF3K_RS02075 291d4e4502900bad48252b85099646bd 423 Pfam PF05816 Toxic anion resistance protein (TelA) 64 387 1.2E-17 T 29-03-2018 IPR008863 Toxic anion resistance SPSF3K_RS10045 30fed3f8571195db318043bfead0c380 358 Pfam PF01757 Acyltransferase family 14 324 2.8E-19 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 SPSF3K_RS01540 070f5632811fb0dc53346f785a061400 305 Gene3D G3DSA:1.10.287.70 1 294 2.1E-6 T 29-03-2018 SPSF3K_RS08960 40faadd746e72b00690cb9065513d5f0 77 Gene3D G3DSA:1.10.287.760 1 65 6.4E-31 T 29-03-2018 IPR023164 YqgQ-like domain SPSF3K_RS08960 40faadd746e72b00690cb9065513d5f0 77 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 61 3.6E-30 T 29-03-2018 IPR009256 Protein of unknown function DUF910 SPSF3K_RS08960 40faadd746e72b00690cb9065513d5f0 77 SUPERFAMILY SSF158379 1 62 4.32E-25 T 29-03-2018 IPR023164 YqgQ-like domain SPSF3K_RS04255 946b05275fb3281031c859e7d17da801 90 Pfam PF04024 PspC domain 5 59 2.0E-14 T 29-03-2018 IPR007168 Phage shock protein, PspC, N-terminal SPSF3K_RS01235 3f3ae8b4fe34c356e7871a07fc5e6b6b 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 302 1.2E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS01235 3f3ae8b4fe34c356e7871a07fc5e6b6b 304 Gene3D G3DSA:1.10.3720.10 1 291 6.2E-39 T 29-03-2018 SPSF3K_RS01235 3f3ae8b4fe34c356e7871a07fc5e6b6b 304 SUPERFAMILY SSF161098 88 285 6.02E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPSF3K_RS04735 c112826bf96aa72729b50e3271b54d31 105 Pfam PF02667 Short chain fatty acid transporter 19 100 6.8E-16 T 29-03-2018 IPR006160 Short chain fatty acid transporter AtoE SPSF3K_RS03005 90fd87ce52e9180f7e1d7ae010b88c0e 279 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 273 17.466 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SPSF3K_RS03005 90fd87ce52e9180f7e1d7ae010b88c0e 279 Pfam PF02673 Bacitracin resistance protein BacA 9 268 1.0E-82 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SPSF3K_RS04960 ccd6e60150009213eff66b6f69573c73 121 Gene3D G3DSA:3.30.300.20 2 121 4.8E-7 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta SPSF3K_RS04960 ccd6e60150009213eff66b6f69573c73 121 SUPERFAMILY SSF82784 21 120 1.7E-11 T 29-03-2018 IPR003718 OsmC/Ohr family SPSF3K_RS04960 ccd6e60150009213eff66b6f69573c73 121 Pfam PF02566 OsmC-like protein 30 117 7.7E-8 T 29-03-2018 IPR003718 OsmC/Ohr family SPSF3K_RS10275 b3cc21e60417b390579e806409733d65 155 Pfam PF11188 Protein of unknown function (DUF2975) 52 155 3.3E-11 T 29-03-2018 IPR021354 Protein of unknown function DUF2975 SPSF3K_RS02560 eb96733307d35c86b39401fdeb6c31c0 264 Pfam PF01148 Cytidylyltransferase family 2 261 6.7E-74 T 29-03-2018 SPSF3K_RS02560 eb96733307d35c86b39401fdeb6c31c0 264 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 223 249 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 SPSF3K_RS10205 511459c7f453b1c3f75596f209c136a8 100 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 23.345 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SPSF3K_RS10205 511459c7f453b1c3f75596f209c136a8 100 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 1.7E-28 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SPSF3K_RS10205 511459c7f453b1c3f75596f209c136a8 100 SUPERFAMILY SSF141000 2 93 9.55E-27 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SPSF3K_RS10205 511459c7f453b1c3f75596f209c136a8 100 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 1.6E-15 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SPSF3K_RS06635 b83094e4949e1a9856b393690a965569 150 Pfam PF08818 Domain of unknown function (DU1801) 19 135 1.4E-16 T 29-03-2018 IPR014922 Domain of unknown function DUF1801 SPSF3K_RS06635 b83094e4949e1a9856b393690a965569 150 SUPERFAMILY SSF159888 6 140 3.92E-13 T 29-03-2018 SPSF3K_RS08940 8c1a8537f308637478c72ea26f54ea25 79 Pfam PF11364 Protein of unknown function (DUF3165) 1 79 6.7E-35 T 29-03-2018 IPR021506 Protein of unknown function DUF3165 SPSF3K_RS08605 763388430102420c071090e42083a120 50 Pfam PF09819 ABC-type cobalt transport system, permease component 1 42 4.8E-11 T 29-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted SPSF3K_RS01955 4e1c9f30e2ca19a2f090298e5187387f 99 Pfam PF11773 Type II secretory pathway pseudopilin 13 94 3.3E-21 T 29-03-2018 IPR021749 Type II secretory pathway pseudopilin SPSF3K_RS05590 f979b82a5006247f0a042c9c52a70a64 123 Pfam PF05713 Bacterial mobilisation protein (MobC) 63 84 1.4E-6 T 29-03-2018 IPR008687 Bacterial mobilisation SPSF3K_RS07175 7a1bee71e0cfb97ea68cc49f55017a8f 81 Pfam PF04226 Transglycosylase associated protein 33 76 4.4E-11 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SPSF3K_RS08690 92e6a474de38e6b363c87939e524f1db 94 Pfam PF01541 GIY-YIG catalytic domain 10 84 5.7E-16 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SPSF3K_RS08690 92e6a474de38e6b363c87939e524f1db 94 Gene3D G3DSA:3.40.1440.10 2 93 1.2E-8 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SPSF3K_RS08690 92e6a474de38e6b363c87939e524f1db 94 SUPERFAMILY SSF82771 9 80 1.83E-13 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily SPSF3K_RS02235 b05d956d84e5475a53450696127cb44a 91 Pfam PF12674 Putative zinc ribbon domain 4 88 2.1E-18 T 29-03-2018 IPR025868 Putative zinc ribbon domain SPSF3K_RS03520 7e9782144ebf029e6e6ea91e1c5cdf70 261 Pfam PF12679 ABC-2 family transporter protein 2 259 1.8E-19 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 SPSF3K_RS05625 f155aef74c54e79a0cd9e1e980c5330b 400 SUPERFAMILY SSF116734 208 399 1.59E-35 T 29-03-2018 SPSF3K_RS05625 f155aef74c54e79a0cd9e1e980c5330b 400 SUPERFAMILY SSF116734 2 203 8.18E-43 T 29-03-2018 SPSF3K_RS05625 f155aef74c54e79a0cd9e1e980c5330b 400 Pfam PF01420 Type I restriction modification DNA specificity domain 219 388 1.6E-15 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 SPSF3K_RS05625 f155aef74c54e79a0cd9e1e980c5330b 400 Pfam PF01420 Type I restriction modification DNA specificity domain 16 191 9.9E-17 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 SPSF3K_RS05625 f155aef74c54e79a0cd9e1e980c5330b 400 Gene3D G3DSA:3.90.220.20 2 184 2.8E-30 T 29-03-2018 SPSF3K_RS05625 f155aef74c54e79a0cd9e1e980c5330b 400 Gene3D G3DSA:3.90.220.20 185 385 1.6E-33 T 29-03-2018 SPSF3K_RS01940 45e601c86079c66e2fcaec26270cb851 282 Pfam PF00482 Type II secretion system (T2SS), protein F 153 273 1.0E-11 T 29-03-2018 IPR018076 Type II secretion system F domain SPSF3K_RS07290 0d728b72ea0e22b9af8dd0978d7573e5 203 Pfam PF09335 SNARE associated Golgi protein 74 191 1.2E-13 T 29-03-2018 IPR032816 SNARE associated Golgi protein SPSF3K_RS05305 f22deaa801e9bbda35c7544815d0b88d 352 Pfam PF13303 Phosphotransferase system, EIIC 15 348 6.1E-93 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPSF3K_RS03705 56a21814215cbd1f8a719cf902414594 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 119 8.8E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPSF3K_RS03705 56a21814215cbd1f8a719cf902414594 124 SUPERFAMILY SSF54593 7 122 1.13E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS03705 56a21814215cbd1f8a719cf902414594 124 Gene3D G3DSA:3.10.180.10 5 124 2.0E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPSF3K_RS02325 87c6b68ba5c7d41d9d21c8ae0996fa94 115 SUPERFAMILY SSF50891 3 111 4.55E-9 T 29-03-2018 IPR029000 Cyclophilin-like domain SPSF3K_RS10215 df1fad135d68b35f3e0912d4cfc64786 271 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 5 268 57.328 T 29-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein SPSF3K_RS10215 df1fad135d68b35f3e0912d4cfc64786 271 Pfam PF03618 Kinase/pyrophosphorylase 7 263 2.7E-94 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 SPSF3K_RS07115 5dbcf18e8c490bf1dea20c7fd9ec8485 323 Pfam PF06081 Aromatic acid exporter family member 1 1 141 3.2E-38 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 SPSF3K_RS07115 5dbcf18e8c490bf1dea20c7fd9ec8485 323 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 308 1.7E-45 T 29-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal SPSF3K_RS06980 7d5e8a4c86329747048b2df5683aa096 189 Pfam PF12822 ECF transporter, substrate-specific component 9 180 2.2E-16 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 SPSF3K_RS02545 872ffde3079cbcfde61d7569cb03b6a5 114 SUPERFAMILY SSF52833 3 113 1.33E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold SPSF3K_RS02545 872ffde3079cbcfde61d7569cb03b6a5 114 Gene3D G3DSA:3.40.30.10 2 114 3.2E-13 T 29-03-2018 SPSF3K_RS02545 872ffde3079cbcfde61d7569cb03b6a5 114 Pfam PF00085 Thioredoxin 21 113 2.6E-6 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 SPSF3K_RS05505 785275b5c9fe437623934adf95e249a5 243 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 92 229 1.8E-8 T 29-03-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 SPSF3K_RS08295 48cf5fb76745898bc3d3d233a85b1d44 240 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 35 221 7.7E-17 T 29-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SPSF3K_RS08295 48cf5fb76745898bc3d3d233a85b1d44 240 Pfam PF04973 Nicotinamide mononucleotide transporter 35 219 1.5E-25 T 29-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SPSF3K_RS03760 9515f7ce3c4eab9dea60dafda1d91ef9 78 Pfam PF11195 Protein of unknown function (DUF2829) 3 76 7.4E-22 T 29-03-2018 IPR021361 Protein of unknown function DUF2829 SPSF3K_RS07190 178f2cc64950e6c6fca5511969b46888 80 Pfam PF04226 Transglycosylase associated protein 32 76 5.3E-12 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 SPSF3K_RS07160 85919c243f9625c5018daed2a9fde410 182 Pfam PF03780 Asp23 family, cell envelope-related function 28 134 4.2E-28 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 SPSF3K_RS09525 28127b9bd48295565fb195d748397014 103 Gene3D G3DSA:3.10.450.150 3 101 4.9E-28 T 29-03-2018 SPSF3K_RS09525 28127b9bd48295565fb195d748397014 103 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 8 101 1.2E-28 T 29-03-2018 IPR009303 Protein of unknown function DUF960 SPSF3K_RS06225 be7eea9e0ebb78b193890157fbe31605 374 Pfam PF01594 AI-2E family transporter 37 359 4.5E-36 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like SPSF3K_RS06215 472a6044383b8f7c7a7fc6a418485be4 309 Pfam PF03547 Membrane transport protein 4 84 9.1E-7 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 SPSF3K_RS01670 ff35c5595d5558c020a700ff2571c7c9 131 Pfam PF03780 Asp23 family, cell envelope-related function 7 110 1.5E-27 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 SPSF3K_RS05495 a8ba8e3a6fed3fae7981099372d1eeb5 114 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 54 101 3.6E-5 T 29-03-2018 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0003713|GO:0006355 SPSF3K_RS01825 34d48054928cfd505dc9731e88f8d0cb 260 Gene3D G3DSA:3.40.50.200 182 258 2.8E-4 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPSF3K_RS08495 6c524d6af65e82239415cefe6d27f612 67 Pfam PF11676 Protein of unknown function (DUF3272) 2 61 5.8E-30 T 29-03-2018 IPR021690 Protein of unknown function DUF3272 SPSF3K_RS03880 2b79591af9db6df07554d60e8d8a7007 55 Pfam PF06100 MCRA family 16 55 4.8E-13 T 29-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 SPSF3K_RS09695 39f1c0db43c9cc8d4efe7b1a39637356 506 Hamap MF_01941 Mid-cell-anchored protein Z [mapZ]. 1 506 23.65 T 29-03-2018 IPR030858 Mid-cell-anchored protein Z GO:0016021|GO:0051301