locus-tag	class	description
SGPB_RS00015	COG0592	DNA-directed DNA polymerase activity
SGPB_RS00020	COG1597	lipid kinase activity
SGPB_RS00030	COG0012	GTP binding
SGPB_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SGPB_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SGPB_RS00190	COG1792	Involved in formation and maintenance of cell shape
SGPB_RS00200	COG3942	CHAP domain
SGPB_RS00210	COG0436	Aminotransferase
SGPB_RS00220	COG0416	fatty acid biosynthetic process
SGPB_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGPB_RS00230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SGPB_RS00245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SGPB_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SGPB_RS00265	COG0151	Belongs to the GarS family
SGPB_RS00270	COG1683	Conserved Protein
SGPB_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SGPB_RS00290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SGPB_RS00300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGPB_RS00335	COG0051	transcription antitermination factor activity, RNA binding
SGPB_RS00345	COG0088	Forms part of the polypeptide exit tunnel
SGPB_RS00350	COG0089	rRNA binding
SGPB_RS00380	COG0255	Belongs to the universal ribosomal protein uL29 family
SGPB_RS00395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SGPB_RS00405	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SGPB_RS00425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SGPB_RS00430	COG1841	ribosomal large subunit assembly
SGPB_RS00440	COG0201	protein transport
SGPB_RS00455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SGPB_RS00460	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SGPB_RS00465	COG0202	RNA polymerase activity
SGPB_RS00470	COG0203	ribosomal protein L17
SGPB_RS00560	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SGPB_RS00570	COG1121	(ABC) transporter
SGPB_RS00575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGPB_RS00595	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SGPB_RS00605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SGPB_RS00610	COG1459	type II secretion system
SGPB_RS00665	COG1266	CAAX protease self-immunity
SGPB_RS00670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SGPB_RS00675	COG1363	Peptidase, m42
SGPB_RS00690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SGPB_RS00695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGPB_RS00705	COG0561	phosphatase activity
SGPB_RS00715	COG4585	Histidine kinase
SGPB_RS00720	COG2197	response regulator
SGPB_RS00740	COG3715	PTS system
SGPB_RS00745	COG3716	PTS system mannose fructose sorbose family IID component
SGPB_RS00755	COG4120	Belongs to the binding-protein-dependent transport system permease family
SGPB_RS00760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGPB_RS00775	COG1396	sequence-specific DNA binding
SGPB_RS00790	COG0564	pseudouridine synthase activity
SGPB_RS00800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGPB_RS00820	COG4667	esterase of the alpha-beta hydrolase superfamily
SGPB_RS00830	COG2017	converts alpha-aldose to the beta-anomer
SGPB_RS00845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SGPB_RS00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SGPB_RS00870	COG1609	Transcriptional regulator
SGPB_RS00875	COG2190	(PTS) system
SGPB_RS00875	COG1263	PTS System
SGPB_RS00875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS00890	COG1363	Peptidase, m42
SGPB_RS00900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS00905	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGPB_RS00910	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS00915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS00920	COG2188	Transcriptional regulator
SGPB_RS00925	COG1482	cell wall glycoprotein biosynthetic process
SGPB_RS00935	COG1653	transport
SGPB_RS00940	COG1175	transmembrane transport
SGPB_RS00945	COG0395	ABC-type sugar transport system, permease component
SGPB_RS00960	COG2188	Transcriptional regulator
SGPB_RS00965	COG1940	carbohydrate kinase activity
SGPB_RS00995	COG3842	ATPase activity
SGPB_RS01035	COG3775	system Galactitol-specific IIC component
SGPB_RS01045	COG3711	transcriptional antiterminator
SGPB_RS01050	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS01055	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGPB_RS01060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS01060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS01065	COG3867	Arabinogalactan endo-beta-1,4-galactanase
SGPB_RS01070	COG2207	Transcriptional regulator
SGPB_RS01075	COG3345	alpha-galactosidase
SGPB_RS01080	COG1653	transport
SGPB_RS01085	COG1175	transmembrane transport
SGPB_RS01090	COG0395	ABC-type sugar transport system, permease component
SGPB_RS01095	COG0366	Alpha amylase catalytic
SGPB_RS01100	COG0366	Alpha amylase catalytic
SGPB_RS01105	COG1609	Transcriptional regulator
SGPB_RS01110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SGPB_RS01115	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SGPB_RS01120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGPB_RS01130	COG1862	Preprotein translocase
SGPB_RS01135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGPB_RS01140	COG4589	Belongs to the CDS family
SGPB_RS01175	COG0242	peptide deformylase activity
SGPB_RS01195	COG0346	lactoylglutathione lyase activity
SGPB_RS01200	COG0561	phosphatase activity
SGPB_RS01210	COG1012	belongs to the aldehyde dehydrogenase family
SGPB_RS01210	COG1454	alcohol dehydrogenase
SGPB_RS01225	COG1185	polyribonucleotide nucleotidyltransferase activity
SGPB_RS01235	COG1045	serine acetyltransferase
SGPB_RS01245	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SGPB_RS01270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SGPB_RS01305	COG1674	ftsk spoiiie
SGPB_RS01355	COG3830	Belongs to the UPF0237 family
SGPB_RS01360	COG2848	UPF0210 protein
SGPB_RS01365	COG0588	phosphoglycerate mutase activity
SGPB_RS01375	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGPB_RS01405	COG0351	phosphomethylpyrimidine kinase
SGPB_RS01405	COG0352	thiamine-phosphate diphosphorylase activity
SGPB_RS01420	COG0668	transmembrane transport
SGPB_RS01435	COG0504	CTP synthase activity
SGPB_RS01450	COG0191	fructose-bisphosphate aldolase activity
SGPB_RS01465	COG1609	Transcriptional regulator
SGPB_RS01475	COG1621	beta-fructofuranosidase activity
SGPB_RS01480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SGPB_RS01490	COG1461	Dihydroxyacetone kinase
SGPB_RS01495	COG0129	dihydroxy-acid dehydratase activity
SGPB_RS01500	COG0028	Belongs to the TPP enzyme family
SGPB_RS01505	COG0440	acetolactate synthase activity
SGPB_RS01510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SGPB_RS01515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SGPB_RS01530	COG1126	abc transporter atp-binding protein
SGPB_RS01535	COG0765	amino acid transport
SGPB_RS01555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGPB_RS01565	COG0719	Fe-S assembly protein
SGPB_RS01570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGPB_RS01580	COG0719	Fe-S assembly protein
SGPB_RS01585	COG1686	Belongs to the peptidase S11 family
SGPB_RS01590	COG4166	transmembrane transport
SGPB_RS01595	COG0601	transmembrane transport
SGPB_RS01600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGPB_RS01605	COG0444	Belongs to the ABC transporter superfamily
SGPB_RS01610	COG4608	Belongs to the ABC transporter superfamily
SGPB_RS01655	COG0527	aspartate kinase activity
SGPB_RS01660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGPB_RS01665	COG1024	Enoyl-CoA hydratase
SGPB_RS01675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGPB_RS01685	COG2070	2-Nitropropane dioxygenase
SGPB_RS01690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SGPB_RS01695	COG1028	Short-chain dehydrogenase reductase Sdr
SGPB_RS01700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGPB_RS01715	COG0439	Biotin carboxylase
SGPB_RS01730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SGPB_RS01740	COG3716	PTS system mannose fructose sorbose family IID component
SGPB_RS01745	COG3715	PTS system
SGPB_RS01755	COG0561	phosphatase activity
SGPB_RS01770	COG2252	PERMEase
SGPB_RS01775	COG0802	atpase or kinase
SGPB_RS01785	COG1316	TRANSCRIPTIONal
SGPB_RS01790	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS01820	COG0537	adenosine 5'-monophosphoramidase activity
SGPB_RS01825	COG1131	(ABC) transporter
SGPB_RS01830	COG4473	ABC transporter
SGPB_RS01840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SGPB_RS01855	COG0195	Participates in both transcription termination and antitermination
SGPB_RS01860	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SGPB_RS01870	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SGPB_RS01875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SGPB_RS01905	COG2860	membrane
SGPB_RS01910	COG0561	phosphatase activity
SGPB_RS01940	COG2188	Transcriptional regulator
SGPB_RS01945	COG2222	sugar isomerase
SGPB_RS01965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS01965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS01975	COG3716	PTS system mannose fructose sorbose family IID component
SGPB_RS01980	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS01980	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS02005	COG3711	transcriptional antiterminator
SGPB_RS02005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS02015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS02015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS02015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SGPB_RS02020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGPB_RS02030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SGPB_RS02050	COG1131	(ABC) transporter
SGPB_RS02060	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SGPB_RS02065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SGPB_RS02080	COG0768	penicillin binding
SGPB_RS02085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGPB_RS02090	COG0513	Belongs to the DEAD box helicase family
SGPB_RS02105	COG1126	abc transporter atp-binding protein
SGPB_RS02120	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SGPB_RS02130	COG3579	cysteine-type endopeptidase activity
SGPB_RS02140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGPB_RS02145	COG3331	DNA recombination
SGPB_RS02155	COG3599	regulation of cell shape
SGPB_RS02160	COG0116	Belongs to the methyltransferase superfamily
SGPB_RS02175	COG1854	S-ribosylhomocysteine lyase activity
SGPB_RS02195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SGPB_RS02200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SGPB_RS02205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SGPB_RS02205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGPB_RS02225	COG4585	Histidine kinase
SGPB_RS02230	COG2197	response regulator
SGPB_RS02240	COG1098	S1 RNA binding domain
SGPB_RS02250	COG1739	Uncharacterized protein family UPF0029
SGPB_RS02255	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SGPB_RS02260	COG1040	competence protein
SGPB_RS02330	COG3557	Belongs to the UPF0374 family
SGPB_RS02335	COG2137	regulation of response to DNA damage stimulus
SGPB_RS02345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGPB_RS02390	COG0519	Catalyzes the synthesis of GMP from XMP
SGPB_RS02400	COG0525	valine-tRNA ligase activity
SGPB_RS02445	COG1309	transcriptional regulator
SGPB_RS02470	COG0742	ribosomal rna small subunit methyltransferase
SGPB_RS02475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SGPB_RS02480	COG3480	Lon protease (S16) C-terminal proteolytic domain
SGPB_RS02490	COG0737	Belongs to the 5'-nucleotidase family
SGPB_RS02495	COG4470	Protein conserved in bacteria
SGPB_RS02510	COG1132	(ABC) transporter
SGPB_RS02515	COG1132	(ABC) transporter
SGPB_RS02520	COG1131	(ABC) transporter
SGPB_RS02530	COG4585	Histidine kinase
SGPB_RS02535	COG2197	response regulator
SGPB_RS02555	COG2186	Transcriptional regulator
SGPB_RS02580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGPB_RS02605	COG1914	H( )-stimulated, divalent metal cation uptake system
SGPB_RS02615	COG0783	Belongs to the Dps family
SGPB_RS02625	COG1940	carbohydrate kinase activity
SGPB_RS02630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SGPB_RS02640	COG1217	gtp-binding protein TYPA
SGPB_RS02675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SGPB_RS02680	COG1799	cell septum assembly
SGPB_RS02695	COG3599	regulation of cell shape
SGPB_RS02720	COG0542	response to heat
SGPB_RS02730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SGPB_RS02735	COG4703	Protein of unknown function (DUF1797)
SGPB_RS02740	COG0765	amino acid transport
SGPB_RS02745	COG1126	abc transporter atp-binding protein
SGPB_RS02770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SGPB_RS02790	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SGPB_RS02795	COG1438	arginine binding
SGPB_RS02800	COG0497	DNA recombination
SGPB_RS02805	COG1307	EDD domain protein, DegV family
SGPB_RS02810	COG2755	lipolytic protein G-D-S-L family
SGPB_RS02815	COG4698	Protein conserved in bacteria
SGPB_RS02835	COG3104	oligopeptide transport
SGPB_RS02840	COG0167	dihydroorotate dehydrogenase activity
SGPB_RS02845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGPB_RS02845	COG3321	synthase
SGPB_RS02845	COG4221	oxidoreductase activity
SGPB_RS02845	COG0604	alcohol dehydrogenase
SGPB_RS02850	COG0640	Transcriptional regulator
SGPB_RS02855	COG2217	Heavy metal translocating P-type atpase
SGPB_RS02860	COG2076	Multidrug Resistance protein
SGPB_RS02895	COG1827	regulation of RNA biosynthetic process
SGPB_RS02905	COG0768	penicillin binding
SGPB_RS02910	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SGPB_RS02925	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGPB_RS02935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SGPB_RS02950	COG0513	Belongs to the DEAD box helicase family
SGPB_RS02980	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SGPB_RS02985	COG0204	Acyl-transferase
SGPB_RS02990	COG1596	polysaccharide export
SGPB_RS02990	COG1555	photosystem II stabilization
SGPB_RS02995	COG2333	competence protein COMEC
SGPB_RS02995	COG0658	competence protein
SGPB_RS03000	COG1466	dna polymerase III delta subunit
SGPB_RS03005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SGPB_RS03010	COG0217	transcriptional regulatory protein
SGPB_RS03025	COG0363	glucosamine-6-phosphate deaminase activity
SGPB_RS03030	COG1187	pseudouridine synthase activity
SGPB_RS03050	COG0546	phosphoglycolate phosphatase activity
SGPB_RS03055	COG4122	O-methyltransferase activity
SGPB_RS03065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SGPB_RS03075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGPB_RS03080	COG0436	Aminotransferase
SGPB_RS03090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SGPB_RS03095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SGPB_RS03100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGPB_RS03105	COG2249	NAD(P)H dehydrogenase (quinone) activity
SGPB_RS03110	COG1476	TRANSCRIPTIONal
SGPB_RS03120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGPB_RS03120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGPB_RS03125	COG0307	riboflavin synthase, alpha
SGPB_RS03130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGPB_RS03130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGPB_RS03145	COG0656	L-ascorbic acid biosynthetic process
SGPB_RS03150	COG0656	L-ascorbic acid biosynthetic process
SGPB_RS03170	COG3859	Proton-coupled thiamine transporter YuaJ
SGPB_RS03175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGPB_RS03180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGPB_RS03185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SGPB_RS03190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SGPB_RS03195	COG0372	Belongs to the citrate synthase family
SGPB_RS03215	COG1609	Transcriptional regulator
SGPB_RS03220	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SGPB_RS03225	COG0251	oxidation-reduction process
SGPB_RS03235	COG1309	transcriptional regulator
SGPB_RS03275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGPB_RS03280	COG1660	Displays ATPase and GTPase activities
SGPB_RS03325	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGPB_RS03325	COG1388	LysM domain
SGPB_RS03335	COG0577	efflux transmembrane transporter activity
SGPB_RS03340	COG1136	(ABC) transporter
SGPB_RS03345	COG0577	efflux transmembrane transporter activity
SGPB_RS03350	COG0745	RESPONSE REGULATOR receiver
SGPB_RS03355	COG5002	protein histidine kinase activity
SGPB_RS03370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SGPB_RS03395	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SGPB_RS03405	COG0513	Belongs to the DEAD box helicase family
SGPB_RS03430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SGPB_RS03435	COG0066	3-isopropylmalate dehydratase activity
SGPB_RS03440	COG1956	GAF domain-containing protein
SGPB_RS03445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SGPB_RS03455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SGPB_RS03455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SGPB_RS03460	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SGPB_RS03465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGPB_RS03475	COG4109	DRTGG domain
SGPB_RS03480	COG0024	Methionine aminopeptidase
SGPB_RS03490	COG2246	polysaccharide biosynthetic process
SGPB_RS03495	COG4708	membrane
SGPB_RS03500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGPB_RS03505	COG1597	lipid kinase activity
SGPB_RS03520	COG0356	it plays a direct role in the translocation of protons across the membrane
SGPB_RS03525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SGPB_RS03560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGPB_RS03575	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SGPB_RS03590	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SGPB_RS03595	COG1074	ATP-dependent DNA helicase activity
SGPB_RS03620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SGPB_RS03635	COG0300	oxidoreductase activity
SGPB_RS03640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SGPB_RS03640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SGPB_RS03645	COG0281	malic enzyme
SGPB_RS03655	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SGPB_RS03710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SGPB_RS03715	COG2384	SAM-dependent methyltransferase
SGPB_RS03725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SGPB_RS03735	COG1088	dTDP-glucose 4,6-dehydratase activity
SGPB_RS03745	COG1051	belongs to the nudix hydrolase family
SGPB_RS03750	COG0628	permease
SGPB_RS03755	COG0457	Tetratricopeptide repeat
SGPB_RS03780	COG2205	protein histidine kinase activity
SGPB_RS03785	COG0745	RESPONSE REGULATOR receiver
SGPB_RS03800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGPB_RS03805	COG0028	Belongs to the TPP enzyme family
SGPB_RS03810	COG3527	Alpha-acetolactate decarboxylase
SGPB_RS03815	COG2801	Transposase and inactivated derivatives
SGPB_RS03820	COG2801	Transposase and inactivated derivatives
SGPB_RS03840	COG3716	PTS system mannose fructose sorbose family IID component
SGPB_RS03850	COG0366	Alpha amylase catalytic
SGPB_RS03860	COG0531	amino acid
SGPB_RS03865	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SGPB_RS03875	COG4120	Belongs to the binding-protein-dependent transport system permease family
SGPB_RS03880	COG3842	ATPase activity
SGPB_RS03895	COG0488	(ABC) transporter
SGPB_RS03905	COG1132	(ABC) transporter
SGPB_RS03910	COG1132	(ABC) transporter
SGPB_RS03915	COG2801	Transposase and inactivated derivatives
SGPB_RS03965	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SGPB_RS03970	COG2190	(PTS) system
SGPB_RS03970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS03970	COG1263	PTS System
SGPB_RS03975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SGPB_RS03980	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGPB_RS03980	COG0022	dehydrogenase e1 component
SGPB_RS03990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGPB_RS04005	COG0095	Lipoate-protein ligase
SGPB_RS04020	COG0583	DNA-binding transcription factor activity
SGPB_RS04030	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SGPB_RS04055	COG2814	Major facilitator Superfamily
SGPB_RS04065	COG0431	NADPH-dependent FMN reductase
SGPB_RS04065	COG1053	succinate dehydrogenase
SGPB_RS04065	COG3976	FMN-binding domain protein
SGPB_RS04075	COG1937	Protein conserved in bacteria
SGPB_RS04085	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGPB_RS04095	COG1418	mRNA catabolic process
SGPB_RS04110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGPB_RS04120	COG0583	DNA-binding transcription factor activity
SGPB_RS04130	COG1028	Short-chain dehydrogenase reductase Sdr
SGPB_RS04145	COG0789	Transcriptional regulator
SGPB_RS04150	COG0656	L-ascorbic acid biosynthetic process
SGPB_RS04180	COG1136	(ABC) transporter
SGPB_RS04185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SGPB_RS04190	COG1011	Hydrolase
SGPB_RS04200	COG0583	DNA-binding transcription factor activity
SGPB_RS04205	COG2855	membrane
SGPB_RS04210	COG1012	belongs to the aldehyde dehydrogenase family
SGPB_RS04215	COG0322	excinuclease ABC activity
SGPB_RS04240	COG1573	uracil-dna glycosylase
SGPB_RS04260	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SGPB_RS04265	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SGPB_RS04295	COG1316	TRANSCRIPTIONal
SGPB_RS04320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SGPB_RS04325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGPB_RS04330	COG1215	transferase activity, transferring glycosyl groups
SGPB_RS04350	COG1216	Glycosyl transferase, family 2
SGPB_RS04370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS04375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS04380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGPB_RS04385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGPB_RS04385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGPB_RS04385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS04390	COG0383	alpha-mannosidase activity
SGPB_RS04405	COG2801	Transposase and inactivated derivatives
SGPB_RS04415	COG0167	dihydroorotate dehydrogenase activity
SGPB_RS04420	COG0284	orotidine-5'-phosphate decarboxylase activity
SGPB_RS04435	COG1881	PFAM PEBP family protein
SGPB_RS04455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SGPB_RS04460	COG0187	DNA topoisomerase II activity
SGPB_RS04465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGPB_RS04470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SGPB_RS04490	COG0539	negative regulation of cytoplasmic translation
SGPB_RS04500	COG1346	cytolysis
SGPB_RS04505	COG1380	Effector of murein hydrolase LrgA
SGPB_RS04520	COG1131	(ABC) transporter
SGPB_RS04525	COG1725	Transcriptional regulator
SGPB_RS04535	COG0205	6-phosphofructokinase activity
SGPB_RS04540	COG0469	pyruvate kinase activity
SGPB_RS04555	COG2824	Alkylphosphonate utilization operon protein PhnA
SGPB_RS04560	COG0765	amino acid transport
SGPB_RS04565	COG1126	abc transporter atp-binding protein
SGPB_RS04575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SGPB_RS04580	COG1115	amino acid carrier protein
SGPB_RS04585	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS04595	COG0406	alpha-ribazole phosphatase activity
SGPB_RS04605	COG0628	permease
SGPB_RS04610	COG1442	glycosyl transferase family 8
SGPB_RS04620	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SGPB_RS04630	COG1104	cysteine desulfurase activity
SGPB_RS04645	COG2357	RelA SpoT domain protein
SGPB_RS04655	COG0564	pseudouridine synthase activity
SGPB_RS04660	COG0280	phosphate acetyltransferase
SGPB_RS04665	COG4221	oxidoreductase activity
SGPB_RS04675	COG0561	phosphatase activity
SGPB_RS04685	COG0477	Major facilitator Superfamily
SGPB_RS04690	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS04695	COG1136	(ABC) transporter
SGPB_RS04700	COG0577	efflux transmembrane transporter activity
SGPB_RS04705	COG0516	GMP reductase activity
SGPB_RS04720	COG2233	PERMEase
SGPB_RS04745	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SGPB_RS04750	COG2890	protein-(glutamine-N5) methyltransferase activity
SGPB_RS04755	COG0009	L-threonylcarbamoyladenylate synthase
SGPB_RS04775	COG1132	(ABC) transporter
SGPB_RS04780	COG1132	(ABC) transporter
SGPB_RS04795	COG3711	transcriptional antiterminator
SGPB_RS04800	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGPB_RS04810	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS04815	COG0519	Catalyzes the synthesis of GMP from XMP
SGPB_RS04815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SGPB_RS04850	COG2376	Dihydroxyacetone kinase
SGPB_RS04855	COG1309	transcriptional regulator
SGPB_RS04860	COG2376	Dihydroxyacetone kinase
SGPB_RS04865	COG1461	Dihydroxyacetone kinase
SGPB_RS04870	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SGPB_RS04875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SGPB_RS04895	COG2188	Transcriptional regulator
SGPB_RS04900	COG1959	2 iron, 2 sulfur cluster binding
SGPB_RS04905	COG1063	alcohol dehydrogenase
SGPB_RS04910	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SGPB_RS04915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SGPB_RS04920	COG4974	Belongs to the 'phage' integrase family
SGPB_RS04930	COG5002	protein histidine kinase activity
SGPB_RS04935	COG0745	RESPONSE REGULATOR receiver
SGPB_RS04940	COG0577	efflux transmembrane transporter activity
SGPB_RS04945	COG1136	(ABC) transporter
SGPB_RS04960	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SGPB_RS04985	COG0758	DNA mediated transformation
SGPB_RS04990	COG0110	maltose O-acetyltransferase activity
SGPB_RS04995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SGPB_RS05000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SGPB_RS05010	COG0577	efflux transmembrane transporter activity
SGPB_RS05015	COG1136	(ABC) transporter
SGPB_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
SGPB_RS05050	COG1904	glucuronate isomerase
SGPB_RS05055	COG0800	Aldolase
SGPB_RS05065	COG3250	beta-galactosidase activity
SGPB_RS05075	COG2211	Major facilitator Superfamily
SGPB_RS05080	COG0488	(ABC) transporter
SGPB_RS05095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGPB_RS05100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGPB_RS05105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SGPB_RS05110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SGPB_RS05130	COG1595	DNA-templated transcription, initiation
SGPB_RS05150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SGPB_RS05155	COG4684	Psort location CytoplasmicMembrane, score
SGPB_RS05160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGPB_RS05175	COG0346	lactoylglutathione lyase activity
SGPB_RS05180	COG3764	Sortase (surface protein transpeptidase)
SGPB_RS05205	COG1079	Belongs to the binding-protein-dependent transport system permease family
SGPB_RS05210	COG4603	Belongs to the binding-protein-dependent transport system permease family
SGPB_RS05220	COG1744	ABC transporter substrate-binding protein PnrA-like
SGPB_RS05225	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SGPB_RS05230	COG2813	Specifically methylates the guanine in position
SGPB_RS05235	COG1072	(Pantothenic acid kinase))
SGPB_RS05245	COG5002	protein histidine kinase activity
SGPB_RS05250	COG0745	RESPONSE REGULATOR receiver
SGPB_RS05260	COG0704	Plays a role in the regulation of phosphate uptake
SGPB_RS05265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGPB_RS05270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGPB_RS05275	COG0581	inorganic phosphate transmembrane transporter activity
SGPB_RS05280	COG0573	inorganic phosphate transmembrane transporter activity
SGPB_RS05295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGPB_RS05315	COG0519	Catalyzes the synthesis of GMP from XMP
SGPB_RS05320	COG0483	inositol monophosphate 1-phosphatase activity
SGPB_RS05325	COG4476	Belongs to the UPF0223 family
SGPB_RS05330	COG1393	Belongs to the ArsC family
SGPB_RS05335	COG0196	riboflavin kinase activity
SGPB_RS05340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SGPB_RS05370	COG1129	ABC transporter
SGPB_RS05385	COG1132	(ABC) transporter
SGPB_RS05390	COG4988	ABC transporter
SGPB_RS05425	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SGPB_RS05470	COG1115	amino acid carrier protein
SGPB_RS05500	COG0561	phosphatase activity
SGPB_RS05505	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS05515	COG0561	phosphatase activity
SGPB_RS05520	COG0561	phosphatase activity
SGPB_RS05525	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS05540	COG1737	Transcriptional regulator
SGPB_RS05545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS05545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS05555	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGPB_RS05560	COG3711	transcriptional antiterminator
SGPB_RS05560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS05565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS05580	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS05610	COG2272	Belongs to the type-B carboxylesterase lipase family
SGPB_RS05615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS05615	COG2190	(PTS) system
SGPB_RS05615	COG1263	PTS System
SGPB_RS05620	COG3711	transcriptional antiterminator
SGPB_RS05635	COG1177	transmembrane transport
SGPB_RS05640	COG1176	ABC-type spermidine putrescine transport system, permease component I
SGPB_RS05650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SGPB_RS05675	COG0285	dihydrofolate synthase activity
SGPB_RS05690	COG2962	Rard protein
SGPB_RS05705	COG0726	polysaccharide deacetylase
SGPB_RS05715	COG4974	Belongs to the 'phage' integrase family
SGPB_RS05760	COG1131	(ABC) transporter
SGPB_RS05780	COG3843	relaxase mobilization nuclease domain protein
SGPB_RS05805	COG0542	response to heat
SGPB_RS05810	COG1396	sequence-specific DNA binding
SGPB_RS05965	COG0270	DNA (cytosine-5-)-methyltransferase activity
SGPB_RS06065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SGPB_RS06070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SGPB_RS06075	COG3425	synthase
SGPB_RS06090	COG1272	protein, Hemolysin III
SGPB_RS06095	COG1304	FMN binding
SGPB_RS06110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SGPB_RS06115	COG1126	abc transporter atp-binding protein
SGPB_RS06120	COG0765	amino acid transport
SGPB_RS06125	COG0765	amino acid transport
SGPB_RS06130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGPB_RS06140	COG0583	DNA-binding transcription factor activity
SGPB_RS06145	COG0656	L-ascorbic acid biosynthetic process
SGPB_RS06155	COG0745	RESPONSE REGULATOR receiver
SGPB_RS06160	COG2357	RelA SpoT domain protein
SGPB_RS06195	COG1132	(ABC) transporter
SGPB_RS06210	COG0242	peptide deformylase activity
SGPB_RS06215	COG0456	acetyltransferase
SGPB_RS06220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SGPB_RS06230	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SGPB_RS06235	COG0602	queuosine metabolic process
SGPB_RS06240	COG0720	synthase
SGPB_RS06245	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SGPB_RS06250	COG1132	(ABC) transporter
SGPB_RS06260	COG0488	(ABC) transporter
SGPB_RS06265	COG0617	tRNA 3'-terminal CCA addition
SGPB_RS06285	COG1705	Flagellar rod assembly protein muramidase FlgJ
SGPB_RS06285	COG1388	LysM domain
SGPB_RS06290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SGPB_RS06295	COG0667	Aldo Keto reductase
SGPB_RS06310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SGPB_RS06310	COG0646	methionine synthase
SGPB_RS06315	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SGPB_RS06320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGPB_RS06320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS06320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SGPB_RS06325	COG1105	Belongs to the carbohydrate kinase PfkB family
SGPB_RS06330	COG1349	DNA-binding transcription factor activity
SGPB_RS06335	COG0492	ferredoxin-NADP+ reductase activity
SGPB_RS06340	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SGPB_RS06345	COG0336	Belongs to the RNA methyltransferase TrmD family
SGPB_RS06350	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SGPB_RS06365	COG1837	Belongs to the UPF0109 family
SGPB_RS06380	COG3177	Filamentation induced by cAMP protein fic
SGPB_RS06405	COG3843	relaxase mobilization nuclease domain protein
SGPB_RS06445	COG0629	single-stranded DNA binding
SGPB_RS06475	COG0577	efflux transmembrane transporter activity
SGPB_RS06480	COG1136	(ABC) transporter
SGPB_RS06495	COG0505	Belongs to the CarA family
SGPB_RS06500	COG0540	Belongs to the ATCase OTCase family
SGPB_RS06510	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SGPB_RS06515	COG0564	pseudouridine synthase activity
SGPB_RS06525	COG0583	DNA-binding transcription factor activity
SGPB_RS06530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SGPB_RS06555	COG0301	tRNA thio-modification
SGPB_RS06560	COG1104	cysteine desulfurase activity
SGPB_RS06570	COG0285	dihydrofolate synthase activity
SGPB_RS06585	COG0287	Prephenate dehydrogenase
SGPB_RS06595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGPB_RS06600	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SGPB_RS06610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SGPB_RS06615	COG1368	sulfuric ester hydrolase activity
SGPB_RS06620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SGPB_RS06625	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SGPB_RS06630	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SGPB_RS06650	COG2195	Cleaves the N-terminal amino acid of tripeptides
SGPB_RS06665	COG3942	CHAP domain
SGPB_RS06675	COG0463	Glycosyl transferase, family 2
SGPB_RS06685	COG1368	sulfuric ester hydrolase activity
SGPB_RS06710	COG0463	Glycosyl transferase, family 2
SGPB_RS06720	COG1091	dTDP-4-dehydrorhamnose reductase activity
SGPB_RS06725	COG2151	metal-sulfur cluster biosynthetic enzyme
SGPB_RS06730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGPB_RS06735	COG0358	DNA primase activity
SGPB_RS06740	COG1970	mechanosensitive ion channel activity
SGPB_RS06750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGPB_RS06755	COG0436	Aminotransferase
SGPB_RS06770	COG0058	SHG alpha-glucan phosphorylase activity
SGPB_RS06775	COG1640	4-alpha-glucanotransferase
SGPB_RS06780	COG1609	Transcriptional regulator
SGPB_RS06790	COG1175	transmembrane transport
SGPB_RS06795	COG3833	ABC-type maltose transport systems, permease component
SGPB_RS06800	COG2816	NAD+ diphosphatase activity
SGPB_RS06805	COG0556	nucleotide-excision repair
SGPB_RS06810	COG0765	amino acid transport
SGPB_RS06815	COG1126	abc transporter atp-binding protein
SGPB_RS06835	COG1187	pseudouridine synthase activity
SGPB_RS06840	COG4166	transmembrane transport
SGPB_RS06845	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS06850	COG2190	(PTS) system
SGPB_RS06850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS06850	COG1263	PTS System
SGPB_RS06875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGPB_RS06880	COG1316	TRANSCRIPTIONal
SGPB_RS06885	COG0077	Prephenate dehydratase
SGPB_RS06890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SGPB_RS06895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGPB_RS06900	COG0481	GTPase activity
SGPB_RS06915	COG1518	maintenance of DNA repeat elements
SGPB_RS06935	COG2801	Transposase and inactivated derivatives
SGPB_RS06950	COG0647	UMP catabolic process
SGPB_RS06955	COG1051	belongs to the nudix hydrolase family
SGPB_RS06965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SGPB_RS06980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SGPB_RS06985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SGPB_RS06990	COG3442	glutamine amidotransferase
SGPB_RS06995	COG0148	phosphopyruvate hydratase activity
SGPB_RS07015	COG1523	belongs to the glycosyl hydrolase 13 family
SGPB_RS07030	COG0107	imidazoleglycerol-phosphate synthase activity
SGPB_RS07040	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SGPB_RS07050	COG0560	Phosphoserine phosphatase
SGPB_RS07055	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SGPB_RS07060	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SGPB_RS07065	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SGPB_RS07085	COG0187	DNA topoisomerase II activity
SGPB_RS07095	COG0772	Belongs to the SEDS family
SGPB_RS07110	COG0038	chloride channel
SGPB_RS07115	COG0287	Prephenate dehydrogenase
SGPB_RS07115	COG1605	Chorismate mutase
SGPB_RS07130	COG0716	FMN binding
SGPB_RS07145	COG0017	Asparaginyl-tRNA synthetase
SGPB_RS07155	COG0436	Aminotransferase
SGPB_RS07180	COG2177	Part of the ABC transporter FtsEX involved in
SGPB_RS07185	COG2884	Cell division ATP-binding protein ftsE
SGPB_RS07190	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SGPB_RS07195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGPB_RS07220	COG1078	dGTPase activity
SGPB_RS07245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SGPB_RS07250	COG0772	Belongs to the SEDS family
SGPB_RS07260	COG1164	Oligoendopeptidase f
SGPB_RS07265	COG0386	Belongs to the glutathione peroxidase family
SGPB_RS07285	COG0588	phosphoglycerate mutase activity
SGPB_RS07295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SGPB_RS07320	COG4443	Transcriptional Coactivator p15 (PC4)
SGPB_RS07330	COG0826	peptidase U32
SGPB_RS07375	COG2183	response to ionizing radiation
SGPB_RS07385	COG0701	Predicted permease
SGPB_RS07390	COG3689	TIGRFAM TIGR03943 family protein
SGPB_RS07395	COG3321	synthase
SGPB_RS07395	COG0604	alcohol dehydrogenase
SGPB_RS07400	COG0789	Transcriptional regulator
SGPB_RS07405	COG0552	protein localization to endoplasmic reticulum
SGPB_RS07410	COG0561	phosphatase activity
SGPB_RS07415	COG0561	phosphatase activity
SGPB_RS07425	COG1196	nuclear chromosome segregation
SGPB_RS07435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SGPB_RS07440	COG5002	protein histidine kinase activity
SGPB_RS07445	COG0745	RESPONSE REGULATOR receiver
SGPB_RS07450	COG1126	abc transporter atp-binding protein
SGPB_RS07455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGPB_RS07460	COG0765	amino acid transport
SGPB_RS07465	COG0765	amino acid transport
SGPB_RS07495	COG0745	RESPONSE REGULATOR receiver
SGPB_RS07510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SGPB_RS07515	COG0438	transferase activity, transferring glycosyl groups
SGPB_RS07525	COG1609	Transcriptional regulator
SGPB_RS07530	COG0006	proline dipeptidase activity
SGPB_RS07540	COG3394	polysaccharide catabolic process
SGPB_RS07545	COG1263	PTS System
SGPB_RS07545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS07565	COG0163	prenyltransferase activity
SGPB_RS07570	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SGPB_RS07575	COG0583	DNA-binding transcription factor activity
SGPB_RS07580	COG1811	Na channel or pump
SGPB_RS07585	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS07590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS07595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS07600	COG1447	Phosphotransferase system cellobiose-specific component IIA
SGPB_RS07615	COG3933	PFAM sigma-54 factor interaction domain-containing protein
SGPB_RS07615	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SGPB_RS07630	COG0778	Nitroreductase
SGPB_RS07650	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS07655	COG2190	(PTS) system
SGPB_RS07655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS07655	COG1263	PTS System
SGPB_RS07665	COG2207	Transcriptional regulator
SGPB_RS07685	COG0557	exoribonuclease II activity
SGPB_RS07695	COG2814	Major facilitator Superfamily
SGPB_RS07700	COG0237	dephospho-CoA kinase activity
SGPB_RS07705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGPB_RS07715	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SGPB_RS07720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SGPB_RS07730	COG1702	phosphate starvation-inducible protein PhoH
SGPB_RS07740	COG4479	Belongs to the UPF0346 family
SGPB_RS07750	COG2996	Protein conserved in bacteria
SGPB_RS07780	COG1674	ftsk spoiiie
SGPB_RS07785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SGPB_RS07795	COG1940	carbohydrate kinase activity
SGPB_RS07800	COG1940	carbohydrate kinase activity
SGPB_RS07805	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS07820	COG0366	Alpha amylase catalytic
SGPB_RS07825	COG1653	transport
SGPB_RS07830	COG0395	ABC-type sugar transport system, permease component
SGPB_RS07835	COG1175	transmembrane transport
SGPB_RS07840	COG0383	alpha-mannosidase activity
SGPB_RS07880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SGPB_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
SGPB_RS07915	COG0534	Mate efflux family protein
SGPB_RS07930	COG0640	Transcriptional regulator
SGPB_RS07935	COG0708	Exodeoxyribonuclease III
SGPB_RS07945	COG1393	Belongs to the ArsC family
SGPB_RS07950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGPB_RS07960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGPB_RS07985	COG0004	ammonium transporteR
SGPB_RS08000	COG1774	PSP1 C-terminal conserved region
SGPB_RS08005	COG0470	DNA polymerase III
SGPB_RS08015	COG1227	inorganic diphosphatase activity
SGPB_RS08015	COG0517	IMP dehydrogenase activity
SGPB_RS08045	COG4471	UPF0298 protein
SGPB_RS08060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SGPB_RS08065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SGPB_RS08070	COG0626	cystathionine gamma-synthase activity
SGPB_RS08075	COG2244	polysaccharide biosynthetic process
SGPB_RS08080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SGPB_RS08085	COG1120	ATPase activity
SGPB_RS08090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGPB_RS08095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGPB_RS08100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGPB_RS08120	COG1227	inorganic diphosphatase activity
SGPB_RS08130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SGPB_RS08135	COG1253	flavin adenine dinucleotide binding
SGPB_RS08140	COG1119	ATPase activity
SGPB_RS08145	COG0025	NhaP-type Na H and K H
SGPB_RS08155	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SGPB_RS08160	COG1242	4 iron, 4 sulfur cluster binding
SGPB_RS08165	COG0671	phosphoesterase, PA-phosphatase related
SGPB_RS08175	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SGPB_RS08185	COG0531	amino acid
SGPB_RS08190	COG0569	domain protein
SGPB_RS08195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SGPB_RS08200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SGPB_RS08205	COG1187	pseudouridine synthase activity
SGPB_RS08220	COG0582	viral genome integration into host DNA
SGPB_RS08240	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SGPB_RS08245	COG3763	UPF0154 protein
SGPB_RS08330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGPB_RS08350	COG1254	Belongs to the acylphosphatase family
SGPB_RS08365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SGPB_RS08375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SGPB_RS08385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SGPB_RS08395	COG1484	DNA-dependent DNA replication
SGPB_RS08435	COG1959	2 iron, 2 sulfur cluster binding
SGPB_RS08440	COG2910	NAD(P)H-binding
SGPB_RS08445	COG1114	Component of the transport system for branched-chain amino acids
SGPB_RS08465	COG1122	ATPase activity
SGPB_RS08475	COG0569	domain protein
SGPB_RS08480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SGPB_RS08490	COG1704	LemA family
SGPB_RS08495	COG0501	Belongs to the peptidase M48B family
SGPB_RS08530	COG2946	Replication initiation factor
SGPB_RS08560	COG0791	NLP P60 protein
SGPB_RS08560	COG0741	lytic transglycosylase activity
SGPB_RS08600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGPB_RS08605	COG1473	amidohydrolase
SGPB_RS08615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SGPB_RS08625	COG0702	epimerase
SGPB_RS08630	COG0789	Transcriptional regulator
SGPB_RS08635	COG1323	Belongs to the UPF0348 family
SGPB_RS08645	COG2226	methyltransferase
SGPB_RS08650	COG0799	negative regulation of ribosome biogenesis
SGPB_RS08655	COG1713	HD superfamily hydrolase involved in NAD metabolism
SGPB_RS08660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SGPB_RS08665	COG1534	Rna-binding protein
SGPB_RS08670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SGPB_RS08675	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SGPB_RS08680	COG2814	Major facilitator Superfamily
SGPB_RS08685	COG1846	Transcriptional regulator
SGPB_RS08700	COG0154	amidase activity
SGPB_RS08705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGPB_RS08710	COG1335	isochorismatase
SGPB_RS08715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SGPB_RS08720	COG0436	Aminotransferase
SGPB_RS08730	COG0589	response to stress
SGPB_RS08735	COG0561	phosphatase activity
SGPB_RS08740	COG0252	asparaginase activity
SGPB_RS08745	COG3655	Transcriptional regulator
SGPB_RS08760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SGPB_RS08775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SGPB_RS08780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SGPB_RS08790	COG1940	carbohydrate kinase activity
SGPB_RS08795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS08795	COG1263	PTS System
SGPB_RS08795	COG2190	(PTS) system
SGPB_RS08800	COG1621	beta-fructofuranosidase activity
SGPB_RS08805	COG1609	Transcriptional regulator
SGPB_RS08810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGPB_RS08820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SGPB_RS08835	COG2131	deaminase
SGPB_RS08840	COG0006	proline dipeptidase activity
SGPB_RS08850	COG0598	Magnesium transport protein CorA
SGPB_RS08865	COG3655	Transcriptional regulator
SGPB_RS08875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SGPB_RS08880	COG0629	single-stranded DNA binding
SGPB_RS08900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SGPB_RS08910	COG3634	alkyl hydroperoxide reductase activity
SGPB_RS08915	COG0450	alkyl hydroperoxide reductase
SGPB_RS08930	COG1194	a g-specific adenine glycosylase
SGPB_RS08940	COG2223	nitrite transmembrane transporter activity
SGPB_RS08945	COG1053	succinate dehydrogenase
SGPB_RS08945	COG3976	FMN-binding domain protein
SGPB_RS08945	COG0431	NADPH-dependent FMN reductase
SGPB_RS09000	COG1063	alcohol dehydrogenase
SGPB_RS09005	COG3118	belongs to the thioredoxin family
SGPB_RS09015	COG0157	Belongs to the NadC ModD family
SGPB_RS09025	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SGPB_RS09045	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SGPB_RS09050	COG0681	Belongs to the peptidase S26 family
SGPB_RS09055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SGPB_RS09075	COG2153	protein acetylation
SGPB_RS09085	COG2723	6-phospho-beta-galactosidase activity
SGPB_RS09100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS09105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SGPB_RS09115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SGPB_RS09135	COG5002	protein histidine kinase activity
SGPB_RS09145	COG0704	Plays a role in the regulation of phosphate uptake
SGPB_RS09150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGPB_RS09155	COG0581	inorganic phosphate transmembrane transporter activity
SGPB_RS09160	COG0573	inorganic phosphate transmembrane transporter activity
SGPB_RS09175	COG0789	Transcriptional regulator
SGPB_RS09190	COG2081	HI0933 family
SGPB_RS09220	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SGPB_RS09230	COG0456	acetyltransferase
SGPB_RS09235	COG1214	PFAM Peptidase M22, glycoprotease
SGPB_RS09240	COG5503	Protein of unknown function (DUF1447)
SGPB_RS09250	COG0493	'glutamate synthase
SGPB_RS09255	COG0069	glutamate synthase activity
SGPB_RS09255	COG0067	glutamate synthase
SGPB_RS09255	COG0070	glutamate synthase
SGPB_RS09260	COG0174	glutamine synthetase
SGPB_RS09265	COG0789	Transcriptional regulator
SGPB_RS09275	COG0126	phosphoglycerate kinase activity
SGPB_RS09285	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGPB_RS09300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SGPB_RS09365	COG0084	hydrolase, TatD family'
SGPB_RS09430	COG2226	methyltransferase
SGPB_RS09435	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SGPB_RS09460	COG0281	malic enzyme
SGPB_RS09465	COG0583	DNA-binding transcription factor activity
SGPB_RS09470	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SGPB_RS09475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGPB_RS09480	COG1696	Membrane protein involved in D-alanine export
SGPB_RS09525	COG0594	ribonuclease P activity
SGPB_RS09540	COG2807	transmembrane transport
SGPB_RS09545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SGPB_RS09570	COG0756	dUTP diphosphatase activity
SGPB_RS09590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SGPB_RS09600	COG0457	Tetratricopeptide repeat
SGPB_RS09600	COG0705	Rhomboid family
SGPB_RS09605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SGPB_RS09610	COG1473	amidohydrolase
SGPB_RS09615	COG2171	N-acyltransferase activity
SGPB_RS09620	COG0166	Belongs to the GPI family
SGPB_RS09630	COG1234	tRNA 3'-trailer cleavage
SGPB_RS09635	COG1268	BioY protein
SGPB_RS09640	COG0343	queuine tRNA-ribosyltransferase activity
SGPB_RS09655	COG3479	Phenolic acid decarboxylase
SGPB_RS09660	COG1695	Transcriptional regulator
SGPB_RS09665	COG1832	CoA-binding protein
SGPB_RS09670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGPB_RS09670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGPB_RS09680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SGPB_RS09695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS09695	COG3711	transcriptional antiterminator
SGPB_RS09700	COG0800	Aldolase
SGPB_RS09705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGPB_RS09740	COG3623	hexulose-6-phosphate isomerase
SGPB_RS09750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SGPB_RS09760	COG3037	sugar-specific permease SgaT UlaA
SGPB_RS09765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SGPB_RS09770	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGPB_RS09770	COG2918	glutathione biosynthetic process
SGPB_RS09785	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SGPB_RS09790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SGPB_RS09795	COG0542	response to heat
SGPB_RS09800	COG4463	regulation of RNA biosynthetic process
SGPB_RS09810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SGPB_RS09825	COG1619	proteins homologs of microcin C7 resistance protein MccF
SGPB_RS09830	COG3590	peptidase
SGPB_RS09845	COG0366	Alpha amylase catalytic
SGPB_RS09850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS09850	COG1263	PTS System
SGPB_RS09855	COG2188	Transcriptional regulator
SGPB_RS09865	COG2255	four-way junction helicase activity
SGPB_RS09870	COG0602	queuosine metabolic process
SGPB_RS09880	COG1328	CTP reductase activity
SGPB_RS09880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SGPB_RS09900	COG4472	Bacterial protein of unknown function (DUF965)
SGPB_RS09905	COG1393	Belongs to the ArsC family
SGPB_RS09915	COG1058	Belongs to the CinA family
SGPB_RS09915	COG1546	Belongs to the CinA family
SGPB_RS09980	COG2190	(PTS) system
SGPB_RS09980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SGPB_RS09980	COG1263	PTS System
SGPB_RS09985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGPB_RS09990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGPB_RS10015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SGPB_RS10050	COG1674	ftsk spoiiie
SGPB_RS10095	COG3759	membrane
SGPB_RS10100	COG1511	domain protein
SGPB_RS10105	COG1309	transcriptional regulator
SGPB_RS10115	COG4466	Protein conserved in bacteria
SGPB_RS10120	COG0305	Participates in initiation and elongation during chromosome replication
SGPB_RS10135	COG0445	tRNA wobble uridine modification
SGPB_RS10150	COG1760	l-serine dehydratase
SGPB_RS10155	COG1760	l-serine dehydratase
SGPB_RS10160	COG0546	phosphoglycolate phosphatase activity
SGPB_RS10165	COG0741	lytic transglycosylase activity
SGPB_RS10180	COG1122	ATPase activity
SGPB_RS10185	COG1122	ATPase activity
SGPB_RS10190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SGPB_RS10200	COG0612	Peptidase, M16
SGPB_RS10205	COG0612	Peptidase, M16
SGPB_RS10230	COG0582	viral genome integration into host DNA
SGPB_RS10240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SGPB_RS10250	COG0516	GMP reductase activity
SGPB_RS10250	COG0517	IMP dehydrogenase activity
SGPB_RS10260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGPB_RS10265	COG0488	(ABC) transporter
SGPB_RS10295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGPB_RS10300	COG1475	DNA binding
SGPB_RS10340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans