locus-tag	class	description
C0J00_RS00010	COG0592	DNA-directed DNA polymerase activity
C0J00_RS00025	COG0012	GTP binding
C0J00_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
C0J00_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C0J00_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C0J00_RS00065	COG0037	tRNA processing
C0J00_RS00070	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C0J00_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0J00_RS00120	COG3022	response to hydroperoxide
C0J00_RS00125	COG0457	Tetratricopeptide repeat
C0J00_RS00125	COG0705	Rhomboid family
C0J00_RS00130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C0J00_RS00135	COG4472	Bacterial protein of unknown function (DUF965)
C0J00_RS00155	COG1328	CTP reductase activity
C0J00_RS00175	COG0602	queuosine metabolic process
C0J00_RS00285	COG3942	CHAP domain
C0J00_RS00295	COG0436	Aminotransferase
C0J00_RS00300	COG1381	Involved in DNA repair and RecF pathway recombination
C0J00_RS00305	COG0416	fatty acid biosynthetic process
C0J00_RS00310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0J00_RS00315	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C0J00_RS00320	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C0J00_RS00330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C0J00_RS00335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C0J00_RS00360	COG1388	LysM domain
C0J00_RS00360	COG3942	CHAP domain
C0J00_RS00390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C0J00_RS00415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C0J00_RS00425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C0J00_RS00435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0J00_RS00435	COG2755	lipolytic protein G-D-S-L family
C0J00_RS00440	COG2188	Transcriptional regulator
C0J00_RS00445	COG1131	(ABC) transporter
C0J00_RS00460	COG1012	belongs to the aldehyde dehydrogenase family
C0J00_RS00460	COG1454	alcohol dehydrogenase
C0J00_RS00470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C0J00_RS00480	COG0534	Mate efflux family protein
C0J00_RS00495	COG2207	Transcriptional regulator
C0J00_RS00515	COG0051	transcription antitermination factor activity, RNA binding
C0J00_RS00525	COG0088	Forms part of the polypeptide exit tunnel
C0J00_RS00535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C0J00_RS00555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C0J00_RS00560	COG0255	Belongs to the universal ribosomal protein uL29 family
C0J00_RS00585	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C0J00_RS00620	COG0201	protein transport
C0J00_RS00625	COG0563	adenylate kinase activity
C0J00_RS00750	COG1121	(ABC) transporter
C0J00_RS00755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0J00_RS00765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0J00_RS00785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0J00_RS00790	COG1459	type II secretion system
C0J00_RS00795	COG4537	Required for transformation and DNA binding
C0J00_RS00825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C0J00_RS00845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C0J00_RS00850	COG1363	Peptidase, m42
C0J00_RS00865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0J00_RS00870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0J00_RS00880	COG2190	(PTS) system
C0J00_RS00880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0J00_RS00880	COG1263	PTS System
C0J00_RS00885	COG1349	DNA-binding transcription factor activity
C0J00_RS00890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C0J00_RS00895	COG0698	ribose 5-phosphate isomerase
C0J00_RS00905	COG1621	beta-fructofuranosidase activity
C0J00_RS00905	COG5492	domain, Protein
C0J00_RS00905	COG3583	domain protein
C0J00_RS00910	COG0561	phosphatase activity
C0J00_RS00925	COG2197	response regulator
C0J00_RS00945	COG3715	PTS system
C0J00_RS00950	COG3716	PTS system mannose fructose sorbose family IID component
C0J00_RS00960	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C0J00_RS00965	COG0459	protein refolding
C0J00_RS00975	COG1619	proteins homologs of microcin C7 resistance protein MccF
C0J00_RS00980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0J00_RS00980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0J00_RS00995	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C0J00_RS01005	COG0542	response to heat
C0J00_RS01010	COG0745	RESPONSE REGULATOR receiver
C0J00_RS01015	COG5002	protein histidine kinase activity
C0J00_RS01035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0J00_RS01055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C0J00_RS01060	COG1744	ABC transporter substrate-binding protein PnrA-like
C0J00_RS01065	COG2188	Transcriptional regulator
C0J00_RS01070	COG2222	sugar isomerase
C0J00_RS01085	COG2186	Transcriptional regulator
C0J00_RS01095	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0J00_RS01100	COG3715	PTS system
C0J00_RS01105	COG3716	PTS system mannose fructose sorbose family IID component
C0J00_RS01115	COG0564	pseudouridine synthase activity
C0J00_RS01120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0J00_RS01140	COG0604	alcohol dehydrogenase
C0J00_RS01145	COG0833	amino acid
C0J00_RS01150	COG2040	homocysteine
C0J00_RS01155	COG1737	Transcriptional regulator
C0J00_RS01160	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C0J00_RS01165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0J00_RS01170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0J00_RS01175	COG3458	cephalosporin-C deacetylase activity
C0J00_RS01190	COG0495	leucyl-tRNA aminoacylation
C0J00_RS01200	COG3655	Transcriptional regulator
C0J00_RS01220	COG1122	ATPase activity
C0J00_RS01240	COG2017	converts alpha-aldose to the beta-anomer
C0J00_RS01250	COG3842	ATPase activity
C0J00_RS01255	COG0366	Alpha amylase catalytic
C0J00_RS01260	COG1609	Transcriptional regulator
C0J00_RS01265	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C0J00_RS01270	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C0J00_RS01275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0J00_RS01290	COG1862	Preprotein translocase
C0J00_RS01300	COG4589	Belongs to the CDS family
C0J00_RS01325	COG1234	tRNA 3'-trailer cleavage
C0J00_RS01340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0J00_RS01345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C0J00_RS01355	COG4509	Sortase family
C0J00_RS01370	COG1193	negative regulation of DNA recombination
C0J00_RS01375	COG4868	Belongs to the UPF0371 family
C0J00_RS01380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C0J00_RS01385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0J00_RS01410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0J00_RS01425	COG0719	Fe-S assembly protein
C0J00_RS01430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C0J00_RS01440	COG0719	Fe-S assembly protein
C0J00_RS01445	COG1686	Belongs to the peptidase S11 family
C0J00_RS01450	COG4166	transmembrane transport
C0J00_RS01455	COG0601	transmembrane transport
C0J00_RS01460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J00_RS01465	COG0444	Belongs to the ABC transporter superfamily
C0J00_RS01470	COG4608	Belongs to the ABC transporter superfamily
C0J00_RS01475	COG4166	transmembrane transport
C0J00_RS01480	COG0601	transmembrane transport
C0J00_RS01485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J00_RS01490	COG0444	Belongs to the ABC transporter superfamily
C0J00_RS01495	COG4608	Belongs to the ABC transporter superfamily
C0J00_RS01550	COG0527	aspartate kinase activity
C0J00_RS01555	COG1024	Enoyl-CoA hydratase
C0J00_RS01560	COG1846	Transcriptional regulator
C0J00_RS01575	COG2070	2-Nitropropane dioxygenase
C0J00_RS01580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C0J00_RS01585	COG1028	Short-chain dehydrogenase reductase Sdr
C0J00_RS01590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0J00_RS01605	COG0439	Biotin carboxylase
C0J00_RS01630	COG3414	Phosphotransferase system galactitol-specific IIB component
C0J00_RS01635	COG3775	system Galactitol-specific IIC component
C0J00_RS01645	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C0J00_RS01650	COG0235	Class ii aldolase
C0J00_RS01665	COG3763	UPF0154 protein
C0J00_RS01670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C0J00_RS01690	COG0582	viral genome integration into host DNA
C0J00_RS01705	COG1187	pseudouridine synthase activity
C0J00_RS01710	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C0J00_RS01720	COG1283	sodium-dependent phosphate transmembrane transporter activity
C0J00_RS01730	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C0J00_RS01755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C0J00_RS01765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C0J00_RS01770	COG3711	transcriptional antiterminator
C0J00_RS01775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS01775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS01775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J00_RS01780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS01780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J00_RS01780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS01785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS01785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS01785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J00_RS01795	COG1011	Hydrolase
C0J00_RS01800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C0J00_RS01815	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C0J00_RS01840	COG0768	penicillin binding
C0J00_RS01850	COG0513	Belongs to the DEAD box helicase family
C0J00_RS01855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J00_RS01865	COG1126	abc transporter atp-binding protein
C0J00_RS01880	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C0J00_RS01895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0J00_RS01915	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C0J00_RS01920	COG1114	Component of the transport system for branched-chain amino acids
C0J00_RS01925	COG0569	domain protein
C0J00_RS01930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C0J00_RS01945	COG1399	metal-binding, possibly nucleic acid-binding protein
C0J00_RS01950	COG0745	RESPONSE REGULATOR receiver
C0J00_RS01955	COG5002	protein histidine kinase activity
C0J00_RS01970	COG1484	DNA-dependent DNA replication
C0J00_RS01980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0J00_RS02000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0J00_RS02015	COG1254	Belongs to the acylphosphatase family
C0J00_RS02025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0J00_RS02055	COG2137	regulation of response to DNA damage stimulus
C0J00_RS02060	COG3231	kanamycin kinase activity
C0J00_RS02080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C0J00_RS02095	COG3716	PTS system mannose fructose sorbose family IID component
C0J00_RS02100	COG3715	PTS system
C0J00_RS02110	COG0561	phosphatase activity
C0J00_RS02120	COG2252	PERMEase
C0J00_RS02125	COG0802	atpase or kinase
C0J00_RS02135	COG1316	TRANSCRIPTIONal
C0J00_RS02140	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C0J00_RS02145	COG0671	phosphoesterase, PA-phosphatase related
C0J00_RS02155	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C0J00_RS02165	COG0025	NhaP-type Na H and K H
C0J00_RS02175	COG0346	lactoylglutathione lyase activity
C0J00_RS02185	COG0525	valine-tRNA ligase activity
C0J00_RS02200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C0J00_RS02205	COG1393	Belongs to the ArsC family
C0J00_RS02210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C0J00_RS02215	COG1253	flavin adenine dinucleotide binding
C0J00_RS02220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C0J00_RS02225	COG1227	inorganic diphosphatase activity
C0J00_RS02230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0J00_RS02235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0J00_RS02240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0J00_RS02245	COG1120	ATPase activity
C0J00_RS02255	COG2244	polysaccharide biosynthetic process
C0J00_RS02260	COG0626	cystathionine gamma-synthase activity
C0J00_RS02265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C0J00_RS02270	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C0J00_RS02315	COG0517	IMP dehydrogenase activity
C0J00_RS02320	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C0J00_RS02325	COG0470	DNA polymerase III
C0J00_RS02350	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C0J00_RS02385	COG0742	ribosomal rna small subunit methyltransferase
C0J00_RS02390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C0J00_RS02395	COG3480	Lon protease (S16) C-terminal proteolytic domain
C0J00_RS02400	COG1609	Transcriptional regulator
C0J00_RS02405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0J00_RS02410	COG1869	D-ribose catabolic process
C0J00_RS02420	COG1172	Belongs to the binding-protein-dependent transport system permease family
C0J00_RS02425	COG1879	ABC-type sugar transport system periplasmic component
C0J00_RS02435	COG0346	lactoylglutathione lyase activity
C0J00_RS02450	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C0J00_RS02455	COG0081	regulation of translation
C0J00_RS02460	COG1132	(ABC) transporter
C0J00_RS02555	COG0233	cytoplasmic translational termination
C0J00_RS02580	COG1702	phosphate starvation-inducible protein PhoH
C0J00_RS02585	COG0668	transmembrane transport
C0J00_RS02595	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C0J00_RS02600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C0J00_RS02625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C0J00_RS02635	COG2364	Membrane
C0J00_RS02640	COG0433	COG0433 Predicted ATPase
C0J00_RS02645	COG2814	Major facilitator Superfamily
C0J00_RS02660	COG0557	exoribonuclease II activity
C0J00_RS02675	COG1609	Transcriptional regulator
C0J00_RS02690	COG0395	ABC-type sugar transport system, permease component
C0J00_RS02695	COG1621	beta-fructofuranosidase activity
C0J00_RS02700	COG1012	belongs to the aldehyde dehydrogenase family
C0J00_RS02705	COG0346	lactoylglutathione lyase activity
C0J00_RS02710	COG0778	Nitroreductase
C0J00_RS02715	COG0038	chloride channel
C0J00_RS02730	COG1609	Transcriptional regulator
C0J00_RS02745	COG0438	transferase activity, transferring glycosyl groups
C0J00_RS02750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C0J00_RS02755	COG2376	Dihydroxyacetone kinase
C0J00_RS02760	COG1461	Dihydroxyacetone kinase
C0J00_RS02765	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C0J00_RS02835	COG0363	glucosamine-6-phosphate deaminase activity
C0J00_RS02840	COG0435	Glutathione S-transferase
C0J00_RS02845	COG1187	pseudouridine synthase activity
C0J00_RS02870	COG0546	phosphoglycolate phosphatase activity
C0J00_RS02875	COG2223	nitrite transmembrane transporter activity
C0J00_RS02880	COG4122	O-methyltransferase activity
C0J00_RS02885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0J00_RS02900	COG1476	TRANSCRIPTIONal
C0J00_RS02910	COG0531	amino acid
C0J00_RS02925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0J00_RS02935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C0J00_RS02950	COG1012	belongs to the aldehyde dehydrogenase family
C0J00_RS02955	COG0726	polysaccharide deacetylase
C0J00_RS02985	COG1956	GAF domain-containing protein
C0J00_RS02990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C0J00_RS03000	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C0J00_RS03000	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C0J00_RS03015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0J00_RS03025	COG4109	DRTGG domain
C0J00_RS03030	COG0024	Methionine aminopeptidase
C0J00_RS03035	COG1295	ribonuclease BN
C0J00_RS03040	COG2246	polysaccharide biosynthetic process
C0J00_RS03045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C0J00_RS03055	COG0625	glutathione transferase activity
C0J00_RS03060	COG0716	FMN binding
C0J00_RS03065	COG0038	chloride channel
C0J00_RS03070	COG0335	large ribosomal subunit rRNA binding
C0J00_RS03085	COG0772	Belongs to the SEDS family
C0J00_RS03090	COG0187	DNA topoisomerase II activity
C0J00_RS03095	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C0J00_RS03115	COG0148	phosphopyruvate hydratase activity
C0J00_RS03120	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0J00_RS03125	COG2195	Cleaves the N-terminal amino acid of tripeptides
C0J00_RS03150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C0J00_RS03155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C0J00_RS03160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C0J00_RS03180	COG0681	Belongs to the peptidase S26 family
C0J00_RS03210	COG1970	mechanosensitive ion channel activity
C0J00_RS03215	COG0358	DNA primase activity
C0J00_RS03220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0J00_RS03225	COG2151	metal-sulfur cluster biosynthetic enzyme
C0J00_RS03230	COG0463	Glycosyl transferase, family 2
C0J00_RS03235	COG1091	dTDP-4-dehydrorhamnose reductase activity
C0J00_RS03260	COG1215	transferase activity, transferring glycosyl groups
C0J00_RS03270	COG1368	sulfuric ester hydrolase activity
C0J00_RS03310	COG1136	(ABC) transporter
C0J00_RS03315	COG0577	efflux transmembrane transporter activity
C0J00_RS03335	COG0228	four-way junction DNA binding
C0J00_RS03340	COG1837	Belongs to the UPF0109 family
C0J00_RS03365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C0J00_RS03370	COG0336	Belongs to the RNA methyltransferase TrmD family
C0J00_RS03375	COG0492	ferredoxin-NADP+ reductase activity
C0J00_RS03380	COG1349	DNA-binding transcription factor activity
C0J00_RS03385	COG1105	Belongs to the carbohydrate kinase PfkB family
C0J00_RS03390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS03390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS03390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J00_RS03395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J00_RS03395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS03395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C0J00_RS03400	COG3942	CHAP domain
C0J00_RS03400	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0J00_RS03420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C0J00_RS03430	COG0488	(ABC) transporter
C0J00_RS03440	COG0534	Mate efflux family protein
C0J00_RS03465	COG3711	transcriptional antiterminator
C0J00_RS03470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0J00_RS03470	COG1263	PTS System
C0J00_RS03470	COG2190	(PTS) system
C0J00_RS03490	COG4977	sequence-specific DNA binding
C0J00_RS03490	COG1917	Cupin 2, conserved barrel domain protein
C0J00_RS03500	COG0673	inositol 2-dehydrogenase activity
C0J00_RS03505	COG2723	6-phospho-beta-galactosidase activity
C0J00_RS03510	COG1940	carbohydrate kinase activity
C0J00_RS03520	COG1744	ABC transporter substrate-binding protein PnrA-like
C0J00_RS03525	COG2723	6-phospho-beta-galactosidase activity
C0J00_RS03530	COG4095	Psort location CytoplasmicMembrane, score
C0J00_RS03555	COG2723	6-phospho-beta-galactosidase activity
C0J00_RS03560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0J00_RS03570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J00_RS03570	COG3711	transcriptional antiterminator
C0J00_RS03575	COG1447	Phosphotransferase system cellobiose-specific component IIA
C0J00_RS03585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0J00_RS03595	COG0561	phosphatase activity
C0J00_RS03600	COG2723	6-phospho-beta-galactosidase activity
C0J00_RS03610	COG0588	phosphoglycerate mutase activity
C0J00_RS03615	COG2723	6-phospho-beta-galactosidase activity
C0J00_RS03625	COG0561	phosphatase activity
C0J00_RS03640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0J00_RS03655	COG0346	lactoylglutathione lyase activity
C0J00_RS03670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0J00_RS03720	COG0242	peptide deformylase activity
C0J00_RS03725	COG0431	NADPH-dependent FMN reductase
C0J00_RS03730	COG3448	diguanylate cyclase activity
C0J00_RS03730	COG4175	Glycine betaine
C0J00_RS03740	COG2357	RelA SpoT domain protein
C0J00_RS03745	COG0745	RESPONSE REGULATOR receiver
C0J00_RS03755	COG0583	DNA-binding transcription factor activity
C0J00_RS03760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C0J00_RS03785	COG1304	FMN binding
C0J00_RS03795	COG3425	synthase
C0J00_RS03805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C0J00_RS03815	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C0J00_RS03825	COG1428	Deoxynucleoside kinase
C0J00_RS04200	COG1132	(ABC) transporter
C0J00_RS04205	COG0657	acetylesterase activity
C0J00_RS04205	COG2755	lipolytic protein G-D-S-L family
C0J00_RS04220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C0J00_RS04245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C0J00_RS04270	COG4120	Belongs to the binding-protein-dependent transport system permease family
C0J00_RS04290	COG0083	homoserine kinase activity
C0J00_RS04295	COG2962	Rard protein
C0J00_RS04300	COG0285	dihydrofolate synthase activity
C0J00_RS04335	COG1176	ABC-type spermidine putrescine transport system, permease component I
C0J00_RS04340	COG1177	transmembrane transport
C0J00_RS04395	COG0560	Phosphoserine phosphatase
C0J00_RS04405	COG1187	pseudouridine synthase activity
C0J00_RS04410	COG2309	aminopeptidase activity
C0J00_RS04435	COG0584	glycerophosphoryl diester phosphodiesterase
C0J00_RS04440	COG0488	(ABC) transporter
C0J00_RS04445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C0J00_RS04450	COG1126	abc transporter atp-binding protein
C0J00_RS04455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J00_RS04465	COG0556	nucleotide-excision repair
C0J00_RS04475	COG3833	ABC-type maltose transport systems, permease component
C0J00_RS04480	COG1175	transmembrane transport
C0J00_RS04495	COG1640	4-alpha-glucanotransferase
C0J00_RS04500	COG0058	SHG alpha-glucan phosphorylase activity
C0J00_RS04510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J00_RS04555	COG0583	DNA-binding transcription factor activity
C0J00_RS04560	COG0284	orotidine-5'-phosphate decarboxylase activity
C0J00_RS04565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C0J00_RS04575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J00_RS04580	COG0765	amino acid transport
C0J00_RS04585	COG1881	PFAM PEBP family protein
C0J00_RS04590	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C0J00_RS04615	COG0187	DNA topoisomerase II activity
C0J00_RS04630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0J00_RS04650	COG0539	negative regulation of cytoplasmic translation
C0J00_RS04665	COG0398	Pfam SNARE associated Golgi protein
C0J00_RS04680	COG0205	6-phosphofructokinase activity
C0J00_RS04685	COG0469	pyruvate kinase activity
C0J00_RS04700	COG2213	PTS system mannitol-specific
C0J00_RS04705	COG3711	transcriptional antiterminator
C0J00_RS04710	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J00_RS04715	COG0246	Mannitol dehydrogenase
C0J00_RS04720	COG2824	Alkylphosphonate utilization operon protein PhnA
C0J00_RS04725	COG0765	amino acid transport
C0J00_RS04730	COG1126	abc transporter atp-binding protein
C0J00_RS04735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J00_RS04760	COG0488	(ABC) transporter
C0J00_RS04765	COG1876	peptidase activity
C0J00_RS04820	COG1937	Protein conserved in bacteria
C0J00_RS04835	COG0425	Belongs to the sulfur carrier protein TusA family
C0J00_RS04835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0J00_RS04840	COG1764	response to oxidative stress
C0J00_RS04845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0J00_RS04850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C0J00_RS04885	COG1396	sequence-specific DNA binding
C0J00_RS04905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C0J00_RS04915	COG0110	maltose O-acetyltransferase activity
C0J00_RS04920	COG0758	DNA mediated transformation
C0J00_RS04925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0J00_RS04950	COG1464	Belongs to the NlpA lipoprotein family
C0J00_RS04965	COG1136	(ABC) transporter
C0J00_RS04970	COG0577	efflux transmembrane transporter activity
C0J00_RS04975	COG0745	RESPONSE REGULATOR receiver
C0J00_RS04980	COG5002	protein histidine kinase activity
C0J00_RS04985	COG1959	2 iron, 2 sulfur cluster binding
C0J00_RS04995	COG0596	Alpha beta hydrolase
C0J00_RS05010	COG4974	Belongs to the 'phage' integrase family
C0J00_RS05045	COG0803	Belongs to the bacterial solute-binding protein 9 family
C0J00_RS05075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C0J00_RS05085	COG1136	(ABC) transporter
C0J00_RS05110	COG3764	Sortase (surface protein transpeptidase)
C0J00_RS05130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C0J00_RS05135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0J00_RS05140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0J00_RS05155	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C0J00_RS05165	COG0095	Lipoate-protein ligase
C0J00_RS05170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0J00_RS05175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0J00_RS05180	COG4684	Psort location CytoplasmicMembrane, score
C0J00_RS05185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0J00_RS05190	COG1132	(ABC) transporter
C0J00_RS05210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C0J00_RS05225	COG2890	protein-(glutamine-N5) methyltransferase activity
C0J00_RS05235	COG1435	thymidine kinase activity
C0J00_RS05260	COG1079	Belongs to the binding-protein-dependent transport system permease family
C0J00_RS05265	COG4603	Belongs to the binding-protein-dependent transport system permease family
C0J00_RS05270	COG3845	ABC transporter
C0J00_RS05275	COG1744	ABC transporter substrate-binding protein PnrA-like
C0J00_RS05280	COG0295	cytidine deaminase activity
C0J00_RS05285	COG2813	Specifically methylates the guanine in position
C0J00_RS05300	COG5002	protein histidine kinase activity
C0J00_RS05305	COG0745	RESPONSE REGULATOR receiver
C0J00_RS05315	COG0704	Plays a role in the regulation of phosphate uptake
C0J00_RS05320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0J00_RS05325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0J00_RS05330	COG0581	inorganic phosphate transmembrane transporter activity
C0J00_RS05335	COG0573	inorganic phosphate transmembrane transporter activity
C0J00_RS05345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0J00_RS05345	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C0J00_RS05350	COG0483	inositol monophosphate 1-phosphatase activity
C0J00_RS05355	COG4476	Belongs to the UPF0223 family
C0J00_RS05365	COG0196	riboflavin kinase activity
C0J00_RS05370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C0J00_RS05425	COG2261	transglycosylase associated protein
C0J00_RS05430	COG0210	DNA helicase
C0J00_RS05435	COG1115	amino acid carrier protein
C0J00_RS05440	COG1115	amino acid carrier protein
C0J00_RS05445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C0J00_RS05450	COG4221	oxidoreductase activity
C0J00_RS05455	COG0280	phosphate acetyltransferase
C0J00_RS05460	COG0564	pseudouridine synthase activity
C0J00_RS05470	COG2357	RelA SpoT domain protein
C0J00_RS05480	COG0346	lactoylglutathione lyase activity
C0J00_RS05490	COG1104	cysteine desulfurase activity
C0J00_RS05510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C0J00_RS05520	COG0628	permease
C0J00_RS05530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0J00_RS05540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C0J00_RS05560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0J00_RS05560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C0J00_RS05575	COG0438	transferase activity, transferring glycosyl groups
C0J00_RS05580	COG1216	Glycosyl transferase, family 2
C0J00_RS05580	COG0463	Glycosyl transferase, family 2
C0J00_RS05585	COG0110	maltose O-acetyltransferase activity
C0J00_RS05590	COG4641	Protein conserved in bacteria
C0J00_RS05590	COG0438	transferase activity, transferring glycosyl groups
C0J00_RS05600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C0J00_RS05625	COG1316	TRANSCRIPTIONal
C0J00_RS05630	COG0322	excinuclease ABC activity
C0J00_RS05635	COG1011	Hydrolase
C0J00_RS05640	COG0656	L-ascorbic acid biosynthetic process
C0J00_RS05650	COG4989	oxidoreductase activity
C0J00_RS05665	COG3583	domain protein
C0J00_RS05670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C0J00_RS05680	COG0142	geranyltranstransferase activity
C0J00_RS05685	COG1252	NADH dehydrogenase
C0J00_RS05695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C0J00_RS05710	COG2188	Transcriptional regulator
C0J00_RS05730	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C0J00_RS05735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C0J00_RS05740	COG3442	glutamine amidotransferase
C0J00_RS05755	COG0488	(ABC) transporter
C0J00_RS05775	COG3842	ATPase activity
C0J00_RS05790	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C0J00_RS05795	COG0457	Tetratricopeptide repeat
C0J00_RS05800	COG0628	permease
C0J00_RS05805	COG1051	belongs to the nudix hydrolase family
C0J00_RS05810	COG2706	6-phosphogluconolactonase activity
C0J00_RS05820	COG1088	dTDP-glucose 4,6-dehydratase activity
C0J00_RS05835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C0J00_RS05840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0J00_RS05855	COG2384	SAM-dependent methyltransferase
C0J00_RS05895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C0J00_RS05895	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C0J00_RS05900	COG0667	Aldo Keto reductase
C0J00_RS05905	COG0300	oxidoreductase activity
C0J00_RS05920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0J00_RS05950	COG0028	Belongs to the TPP enzyme family
C0J00_RS05960	COG0647	UMP catabolic process
C0J00_RS05965	COG1051	belongs to the nudix hydrolase family
C0J00_RS05975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0J00_RS05995	COG1104	cysteine desulfurase activity
C0J00_RS06000	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0J00_RS06000	COG3942	CHAP domain
C0J00_RS06015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0J00_RS06045	COG0505	Belongs to the CarA family
C0J00_RS06050	COG0540	Belongs to the ATCase OTCase family
C0J00_RS06055	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C0J00_RS06060	COG0564	pseudouridine synthase activity
C0J00_RS06070	COG0583	DNA-binding transcription factor activity
C0J00_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
C0J00_RS06105	COG4129	membrane
C0J00_RS06185	COG2226	methyltransferase
C0J00_RS06195	COG2207	Transcriptional regulator
C0J00_RS06195	COG3708	Transcriptional regulator
C0J00_RS06210	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0J00_RS06215	COG4824	toxin secretion phage lysis holin
C0J00_RS06285	COG0740	serine-type endopeptidase activity
C0J00_RS06290	COG4695	Portal protein
C0J00_RS06345	COG3041	Addiction module toxin RelE StbE family
C0J00_RS06365	COG2337	Toxic component of a toxin-antitoxin (TA) module
C0J00_RS06425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C0J00_RS06455	COG0488	(ABC) transporter
C0J00_RS06500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C0J00_RS06520	COG0710	3-dehydroquinate dehydratase activity
C0J00_RS06525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C0J00_RS06530	COG1368	sulfuric ester hydrolase activity
C0J00_RS06570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0J00_RS06610	COG0356	it plays a direct role in the translocation of protons across the membrane
C0J00_RS06620	COG0297	glycogen (starch) synthase activity
C0J00_RS06625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C0J00_RS06630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C0J00_RS06635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C0J00_RS06640	COG1523	belongs to the glycosyl hydrolase 13 family
C0J00_RS06645	COG1597	lipid kinase activity
C0J00_RS06650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C0J00_RS06655	COG4708	membrane
C0J00_RS06680	COG1660	Displays ATPase and GTPase activities
C0J00_RS06685	COG1074	ATP-dependent DNA helicase activity
C0J00_RS06695	COG2321	neutral zinc metallopeptidase
C0J00_RS06710	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C0J00_RS06755	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C0J00_RS06760	COG0511	ligase activity, forming carbon-carbon bonds
C0J00_RS06770	COG2851	Citrate transporter
C0J00_RS06790	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C0J00_RS06800	COG0436	Aminotransferase
C0J00_RS06805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0J00_RS06805	COG1199	ATP-dependent helicase activity
C0J00_RS06810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0J00_RS06820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0J00_RS06830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0J00_RS06865	COG1131	(ABC) transporter
C0J00_RS06870	COG2177	Part of the ABC transporter FtsEX involved in
C0J00_RS06875	COG2884	Cell division ATP-binding protein ftsE
C0J00_RS06885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C0J00_RS06905	COG1078	dGTPase activity
C0J00_RS06925	COG0149	triose-phosphate isomerase activity
C0J00_RS06935	COG0772	Belongs to the SEDS family
C0J00_RS06945	COG1164	Oligoendopeptidase f
C0J00_RS06960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C0J00_RS06970	COG3859	Proton-coupled thiamine transporter YuaJ
C0J00_RS06985	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0J00_RS06990	COG3304	Inner membrane component domain
C0J00_RS06995	COG0588	phosphoglycerate mutase activity
C0J00_RS07010	COG4443	Transcriptional Coactivator p15 (PC4)
C0J00_RS07030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C0J00_RS07045	COG3091	SprT-like family
C0J00_RS07050	COG2183	response to ionizing radiation
C0J00_RS07055	COG1114	Component of the transport system for branched-chain amino acids
C0J00_RS07060	COG0704	Plays a role in the regulation of phosphate uptake
C0J00_RS07065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0J00_RS07070	COG0581	inorganic phosphate transmembrane transporter activity
C0J00_RS07075	COG0573	inorganic phosphate transmembrane transporter activity
C0J00_RS07080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C0J00_RS07085	COG5002	protein histidine kinase activity
C0J00_RS07090	COG0745	RESPONSE REGULATOR receiver
C0J00_RS07180	COG2274	protein secretion by the type I secretion system
C0J00_RS07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0J00_RS07215	COG0346	lactoylglutathione lyase activity
C0J00_RS07235	COG0701	Predicted permease
C0J00_RS07240	COG3689	TIGRFAM TIGR03943 family protein
C0J00_RS07245	COG0531	amino acid
C0J00_RS07250	COG0552	protein localization to endoplasmic reticulum
C0J00_RS07255	COG0561	phosphatase activity
C0J00_RS07260	COG0561	phosphatase activity
C0J00_RS07265	COG1196	nuclear chromosome segregation
C0J00_RS07275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C0J00_RS07280	COG5002	protein histidine kinase activity
C0J00_RS07285	COG0745	RESPONSE REGULATOR receiver
C0J00_RS07290	COG1126	abc transporter atp-binding protein
C0J00_RS07295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J00_RS07300	COG0765	amino acid transport
C0J00_RS07305	COG0765	amino acid transport
C0J00_RS07310	COG2197	response regulator
C0J00_RS07315	COG4585	Histidine kinase
C0J00_RS07325	COG1131	(ABC) transporter
C0J00_RS07335	COG0658	competence protein
C0J00_RS07335	COG2333	competence protein COMEC
C0J00_RS07340	COG1555	photosystem II stabilization
C0J00_RS07340	COG1596	polysaccharide export
C0J00_RS07345	COG0204	Acyl-transferase
C0J00_RS07355	COG1755	Isoprenylcysteine carboxyl methyltransferase
C0J00_RS07360	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C0J00_RS07370	COG0513	Belongs to the DEAD box helicase family
C0J00_RS07400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C0J00_RS07410	COG1181	Belongs to the D-alanine--D-alanine ligase family
C0J00_RS07420	COG0768	penicillin binding
C0J00_RS07430	COG0167	dihydroorotate dehydrogenase activity
C0J00_RS07460	COG2755	lipolytic protein G-D-S-L family
C0J00_RS07465	COG1307	EDD domain protein, DegV family
C0J00_RS07470	COG0497	DNA recombination
C0J00_RS07480	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C0J00_RS07500	COG0667	Aldo Keto reductase
C0J00_RS07505	COG1272	protein, Hemolysin III
C0J00_RS07515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C0J00_RS07520	COG1126	abc transporter atp-binding protein
C0J00_RS07525	COG0765	amino acid transport
C0J00_RS07530	COG4703	Protein of unknown function (DUF1797)
C0J00_RS07535	COG0542	response to heat
C0J00_RS07550	COG0494	nUDIX hydrolase
C0J00_RS07565	COG3599	regulation of cell shape
C0J00_RS07585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C0J00_RS07600	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C0J00_RS07620	COG1217	gtp-binding protein TYPA
C0J00_RS07635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0J00_RS07640	COG1940	carbohydrate kinase activity
C0J00_RS07650	COG0783	Belongs to the Dps family
C0J00_RS07655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C0J00_RS07660	COG1132	(ABC) transporter
C0J00_RS07665	COG1132	(ABC) transporter
C0J00_RS07675	COG4470	Protein conserved in bacteria
C0J00_RS07690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0J00_RS07695	COG1321	iron dependent repressor
C0J00_RS07695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0J00_RS07700	COG1121	(ABC) transporter
C0J00_RS07705	COG0803	Belongs to the bacterial solute-binding protein 9 family
C0J00_RS07715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C0J00_RS07725	COG0494	nUDIX hydrolase
C0J00_RS07735	COG0673	inositol 2-dehydrogenase activity
C0J00_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
C0J00_RS07785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0J00_RS07785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0J00_RS07805	COG1304	FMN binding
C0J00_RS07810	COG0708	Exodeoxyribonuclease III
C0J00_RS07815	COG2267	carboxylic ester hydrolase activity
C0J00_RS07825	COG1418	mRNA catabolic process
C0J00_RS07905	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C0J00_RS07910	COG1739	Uncharacterized protein family UPF0029
C0J00_RS07930	COG1098	S1 RNA binding domain
C0J00_RS07940	COG2197	response regulator
C0J00_RS07945	COG4585	Histidine kinase
C0J00_RS07955	COG0515	serine threonine protein kinase
C0J00_RS07955	COG2815	serine threonine protein kinase
C0J00_RS07965	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0J00_RS07965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0J00_RS07975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C0J00_RS07980	COG1758	RNA polymerase activity
C0J00_RS08005	COG0116	Belongs to the methyltransferase superfamily
C0J00_RS08015	COG3599	regulation of cell shape
C0J00_RS08025	COG3331	DNA recombination
C0J00_RS08030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0J00_RS08035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J00_RS08050	COG1323	Belongs to the UPF0348 family
C0J00_RS08055	COG2226	methyltransferase
C0J00_RS08060	COG0799	negative regulation of ribosome biogenesis
C0J00_RS08070	COG1713	HD superfamily hydrolase involved in NAD metabolism
C0J00_RS08075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C0J00_RS08080	COG1534	Rna-binding protein
C0J00_RS08085	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C0J00_RS08110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0J00_RS08110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C0J00_RS08115	COG1447	Phosphotransferase system cellobiose-specific component IIA
C0J00_RS08155	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C0J00_RS08170	COG1335	isochorismatase
C0J00_RS08175	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C0J00_RS08180	COG0436	Aminotransferase
C0J00_RS08190	COG0561	phosphatase activity
C0J00_RS08195	COG0252	asparaginase activity
C0J00_RS08205	COG4989	oxidoreductase activity
C0J00_RS08210	COG0737	Belongs to the 5'-nucleotidase family
C0J00_RS08220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C0J00_RS08235	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C0J00_RS08240	COG0195	Participates in both transcription termination and antitermination
C0J00_RS08270	COG4473	ABC transporter
C0J00_RS08275	COG1131	(ABC) transporter
C0J00_RS08280	COG0537	adenosine 5'-monophosphoramidase activity
C0J00_RS08300	COG0569	domain protein
C0J00_RS08305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C0J00_RS08320	COG0561	phosphatase activity
C0J00_RS08325	COG0561	phosphatase activity
C0J00_RS08330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C0J00_RS08340	COG0736	holo-[acyl-carrier-protein] synthase activity
C0J00_RS08345	COG0653	protein targeting
C0J00_RS08355	COG1482	cell wall glycoprotein biosynthetic process
C0J00_RS08360	COG1940	carbohydrate kinase activity
C0J00_RS08365	COG2190	(PTS) system
C0J00_RS08365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0J00_RS08365	COG1263	PTS System
C0J00_RS08370	COG1621	beta-fructofuranosidase activity
C0J00_RS08375	COG1609	Transcriptional regulator
C0J00_RS08380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0J00_RS08465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C0J00_RS08520	COG0542	response to heat
C0J00_RS08525	COG0551	DNA topoisomerase type I activity
C0J00_RS08525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0J00_RS08645	COG2131	deaminase
C0J00_RS08650	COG0006	proline dipeptidase activity
C0J00_RS08675	COG2851	Citrate transporter
C0J00_RS08680	COG0473	3-isopropylmalate dehydrogenase activity
C0J00_RS08695	COG0360	Binds together with S18 to 16S ribosomal RNA
C0J00_RS08710	COG1194	a g-specific adenine glycosylase
C0J00_RS08715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0J00_RS08735	COG0789	Transcriptional regulator
C0J00_RS08740	COG0110	maltose O-acetyltransferase activity
C0J00_RS08745	COG0702	epimerase
C0J00_RS08755	COG1174	glycine betaine transport
C0J00_RS08770	COG1063	alcohol dehydrogenase
C0J00_RS08775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C0J00_RS08780	COG3118	belongs to the thioredoxin family
C0J00_RS08785	COG1902	pentaerythritol trinitrate reductase activity
C0J00_RS08810	COG0765	amino acid transport
C0J00_RS08815	COG1126	abc transporter atp-binding protein
C0J00_RS08840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C0J00_RS08870	COG0371	Dehydrogenase
C0J00_RS08885	COG0004	ammonium transporteR
C0J00_RS08905	COG1396	sequence-specific DNA binding
C0J00_RS08935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C0J00_RS08940	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C0J00_RS08955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0J00_RS08960	COG0789	Transcriptional regulator
C0J00_RS08970	COG0756	dUTP diphosphatase activity
C0J00_RS08985	COG2832	Protein of unknown function (DUF454)
C0J00_RS08995	COG1053	succinate dehydrogenase
C0J00_RS08995	COG3976	FMN-binding domain protein
C0J00_RS08995	COG0431	NADPH-dependent FMN reductase
C0J00_RS09005	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C0J00_RS09010	COG0681	Belongs to the peptidase S26 family
C0J00_RS09015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C0J00_RS09020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C0J00_RS09025	COG1882	Formate acetyltransferase
C0J00_RS09050	COG2936	dipeptidyl-peptidase activity
C0J00_RS09055	COG4166	transmembrane transport
C0J00_RS09060	COG0577	efflux transmembrane transporter activity
C0J00_RS09060	COG1136	(ABC) transporter
C0J00_RS09085	COG1266	CAAX protease self-immunity
C0J00_RS09095	COG0789	Transcriptional regulator
C0J00_RS09100	COG5504	Zn-dependent protease
C0J00_RS09125	COG2081	HI0933 family
C0J00_RS09135	COG1104	cysteine desulfurase activity
C0J00_RS09160	COG1214	PFAM Peptidase M22, glycoprotease
C0J00_RS09165	COG5503	Protein of unknown function (DUF1447)
C0J00_RS09175	COG3942	CHAP domain
C0J00_RS09180	COG0174	glutamine synthetase
C0J00_RS09185	COG0789	Transcriptional regulator
C0J00_RS09200	COG0126	phosphoglycerate kinase activity
C0J00_RS09205	COG0656	L-ascorbic acid biosynthetic process
C0J00_RS09210	COG2188	Transcriptional regulator
C0J00_RS09250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C0J00_RS09285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J00_RS09315	COG0084	hydrolase, TatD family'
C0J00_RS09325	COG0534	Mate efflux family protein
C0J00_RS09345	COG1847	R3H domain protein
C0J00_RS09345	COG1847	R3H domain protein
C0J00_RS09355	COG0594	ribonuclease P activity
C0J00_RS09375	COG0668	transmembrane transport
C0J00_RS09380	COG2814	Major facilitator Superfamily
C0J00_RS09395	COG0351	phosphomethylpyrimidine kinase
C0J00_RS09435	COG1420	regulation of RNA biosynthetic process
C0J00_RS09440	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0J00_RS09450	COG0588	phosphoglycerate mutase activity
C0J00_RS09485	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C0J00_RS09505	COG1045	serine acetyltransferase
C0J00_RS09515	COG1185	polyribonucleotide nucleotidyltransferase activity
C0J00_RS09520	COG0390	transport system, permease component
C0J00_RS09525	COG4619	ABC transporter
C0J00_RS09565	COG1335	isochorismatase
C0J00_RS09575	COG0242	peptide deformylase activity
C0J00_RS09580	COG0095	Lipoate-protein ligase
C0J00_RS09590	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0J00_RS09595	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0J00_RS09595	COG0022	dehydrogenase e1 component
C0J00_RS09600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0J00_RS09610	COG1846	Transcriptional regulator
C0J00_RS09615	COG2176	DNA-directed DNA polymerase activity
C0J00_RS09625	COG1268	BioY protein
C0J00_RS09640	COG0343	queuine tRNA-ribosyltransferase activity
C0J00_RS09650	COG1597	lipid kinase activity
C0J00_RS09660	COG1263	PTS System
C0J00_RS09660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0J00_RS09670	COG3590	peptidase
C0J00_RS09675	COG3958	Transketolase
C0J00_RS09680	COG3959	Transketolase, thiamine diphosphate binding domain
C0J00_RS09695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J00_RS09710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0J00_RS09715	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C0J00_RS09720	COG2188	Transcriptional regulator
C0J00_RS09725	COG0366	Alpha amylase catalytic
C0J00_RS09730	COG1263	PTS System
C0J00_RS09730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0J00_RS09735	COG2188	Transcriptional regulator
C0J00_RS09740	COG1929	Belongs to the glycerate kinase type-1 family
C0J00_RS09745	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C0J00_RS09770	COG0737	Belongs to the 5'-nucleotidase family
C0J00_RS09785	COG1363	Peptidase, m42
C0J00_RS09805	COG2190	(PTS) system
C0J00_RS09805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0J00_RS09805	COG1263	PTS System
C0J00_RS09810	COG1609	Transcriptional regulator
C0J00_RS09815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C0J00_RS09830	COG1051	belongs to the nudix hydrolase family
C0J00_RS09845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C0J00_RS09875	COG1674	ftsk spoiiie
C0J00_RS09950	COG2226	methyltransferase
C0J00_RS09970	COG0166	Belongs to the GPI family
C0J00_RS09980	COG3711	transcriptional antiterminator
C0J00_RS09980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J00_RS09990	COG3730	PTS system glucitol sorbitol-specific
C0J00_RS09995	COG3732	PTS system glucitol sorbitol-specific
C0J00_RS10010	COG0166	Belongs to the GPI family
C0J00_RS10030	COG1393	Belongs to the ArsC family
C0J00_RS10035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C0J00_RS10040	COG1546	Belongs to the CinA family
C0J00_RS10040	COG1058	Belongs to the CinA family
C0J00_RS10050	COG2818	Glycosylase
C0J00_RS10085	COG1764	response to oxidative stress
C0J00_RS10090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0J00_RS10095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0J00_RS10110	COG0531	amino acid
C0J00_RS10115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C0J00_RS10120	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C0J00_RS10125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C0J00_RS10140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0J00_RS10145	COG2217	Heavy metal translocating P-type atpase
C0J00_RS10160	COG0494	nUDIX hydrolase
C0J00_RS10165	COG1668	transmembrane transport
C0J00_RS10170	COG4152	abc transporter atp-binding protein
C0J00_RS10175	COG1695	Transcriptional regulator
C0J00_RS10190	COG3759	membrane
C0J00_RS10200	COG1053	succinate dehydrogenase
C0J00_RS10205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C0J00_RS10220	COG0305	Participates in initiation and elongation during chromosome replication
C0J00_RS10245	COG0537	adenosine 5'-monophosphoramidase activity
C0J00_RS10255	COG1760	l-serine dehydratase
C0J00_RS10260	COG1760	l-serine dehydratase
C0J00_RS10270	COG0741	lytic transglycosylase activity
C0J00_RS10275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C0J00_RS10290	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C0J00_RS10300	COG0612	Peptidase, M16
C0J00_RS10315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C0J00_RS10325	COG0517	IMP dehydrogenase activity
C0J00_RS10325	COG0516	GMP reductase activity
C0J00_RS10365	COG0436	Aminotransferase
C0J00_RS10380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C0J00_RS10385	COG0488	(ABC) transporter
C0J00_RS10410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0J00_RS10415	COG1475	DNA binding