locus-tag	class	description
BUM80_RS00020	COG0789	Transcriptional regulator
BUM80_RS00025	COG0174	glutamine synthetase
BUM80_RS00050	COG0732	type I restriction modification DNA specificity domain
BUM80_RS00055	COG4974	Belongs to the 'phage' integrase family
BUM80_RS00120	COG0484	heat shock protein binding
BUM80_RS00135	COG0537	adenosine 5'-monophosphoramidase activity
BUM80_RS00140	COG1131	(ABC) transporter
BUM80_RS00165	COG3290	protein histidine kinase activity
BUM80_RS00175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUM80_RS00280	COG1266	CAAX protease self-immunity
BUM80_RS00300	COG0195	Participates in both transcription termination and antitermination
BUM80_RS00305	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BUM80_RS00360	COG0519	Catalyzes the synthesis of GMP from XMP
BUM80_RS00370	COG0525	valine-tRNA ligase activity
BUM80_RS00395	COG3711	transcriptional antiterminator
BUM80_RS00400	COG2190	(PTS) system
BUM80_RS00400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUM80_RS00400	COG1263	PTS System
BUM80_RS00415	COG0456	acetyltransferase
BUM80_RS00420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUM80_RS00420	COG0072	phenylalanine-tRNA ligase activity
BUM80_RS00435	COG3620	sequence-specific DNA binding
BUM80_RS00440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BUM80_RS00460	COG1045	serine acetyltransferase
BUM80_RS00475	COG0215	cysteine-tRNA ligase activity
BUM80_RS00480	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BUM80_RS00495	COG0577	efflux transmembrane transporter activity
BUM80_RS00500	COG1136	(ABC) transporter
BUM80_RS00505	COG0577	efflux transmembrane transporter activity
BUM80_RS00510	COG0745	RESPONSE REGULATOR receiver
BUM80_RS00515	COG5002	protein histidine kinase activity
BUM80_RS00520	COG0191	fructose-bisphosphate aldolase activity
BUM80_RS00525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BUM80_RS00535	COG0765	amino acid transport
BUM80_RS00540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUM80_RS00550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BUM80_RS00550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BUM80_RS00590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUM80_RS00605	COG1573	uracil-dna glycosylase
BUM80_RS00620	COG1114	Component of the transport system for branched-chain amino acids
BUM80_RS00625	COG1363	Peptidase, m42
BUM80_RS00670	COG4555	ABC transporter
BUM80_RS00685	COG1404	Belongs to the peptidase S8 family
BUM80_RS00700	COG3775	system Galactitol-specific IIC component
BUM80_RS00735	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BUM80_RS00755	COG0785	Cytochrome C biogenesis protein
BUM80_RS00760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUM80_RS00765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUM80_RS00765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUM80_RS00770	COG2207	Transcriptional regulator
BUM80_RS00770	COG4753	response regulator
BUM80_RS00775	COG2972	Histidine kinase
BUM80_RS00785	COG3064	Membrane
BUM80_RS00790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUM80_RS00805	COG1940	carbohydrate kinase activity
BUM80_RS00825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BUM80_RS00830	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BUM80_RS00840	COG0300	oxidoreductase activity
BUM80_RS00860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUM80_RS00870	COG1187	pseudouridine synthase activity
BUM80_RS00875	COG1217	gtp-binding protein TYPA
BUM80_RS00895	COG1136	(ABC) transporter
BUM80_RS00910	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BUM80_RS00915	COG0284	orotidine-5'-phosphate decarboxylase activity
BUM80_RS00945	COG1131	(ABC) transporter
BUM80_RS00970	COG1304	FMN binding
BUM80_RS00980	COG1304	FMN binding
BUM80_RS01000	COG0352	thiamine-phosphate diphosphorylase activity
BUM80_RS01015	COG4172	Belongs to the ABC transporter superfamily
BUM80_RS01025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BUM80_RS01040	COG0352	thiamine-phosphate diphosphorylase activity
BUM80_RS01060	COG2217	Heavy metal translocating P-type atpase
BUM80_RS01070	COG0028	Belongs to the TPP enzyme family
BUM80_RS01085	COG2723	6-phospho-beta-galactosidase activity
BUM80_RS01090	COG1482	cell wall glycoprotein biosynthetic process
BUM80_RS01100	COG0789	Transcriptional regulator
BUM80_RS01110	COG2081	HI0933 family
BUM80_RS01115	COG1307	EDD domain protein, DegV family
BUM80_RS01125	COG2131	deaminase
BUM80_RS01130	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BUM80_RS01175	COG0517	IMP dehydrogenase activity
BUM80_RS01175	COG0617	tRNA 3'-terminal CCA addition
BUM80_RS01175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BUM80_RS01185	COG2884	Cell division ATP-binding protein ftsE
BUM80_RS01190	COG2177	Part of the ABC transporter FtsEX involved in
BUM80_RS01195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUM80_RS01195	COG2190	(PTS) system
BUM80_RS01195	COG1263	PTS System
BUM80_RS01205	COG0513	Belongs to the DEAD box helicase family
BUM80_RS01220	COG0167	dihydroorotate dehydrogenase activity
BUM80_RS01230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BUM80_RS01235	COG4470	Protein conserved in bacteria
BUM80_RS01250	COG0488	(ABC) transporter
BUM80_RS01305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BUM80_RS01305	COG1328	CTP reductase activity
BUM80_RS01315	COG4443	Transcriptional Coactivator p15 (PC4)
BUM80_RS01320	COG1268	BioY protein
BUM80_RS01360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUM80_RS01365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUM80_RS01370	COG1136	(ABC) transporter
BUM80_RS01375	COG0577	efflux transmembrane transporter activity
BUM80_RS01380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUM80_RS01380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUM80_RS01395	COG4989	oxidoreductase activity
BUM80_RS01405	COG1028	Short-chain dehydrogenase reductase Sdr
BUM80_RS01435	COG0745	RESPONSE REGULATOR receiver
BUM80_RS01440	COG5002	protein histidine kinase activity
BUM80_RS01465	COG0772	Belongs to the SEDS family
BUM80_RS01470	COG0693	protein deglycase activity
BUM80_RS01480	COG0187	DNA topoisomerase II activity
BUM80_RS01485	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BUM80_RS01535	COG0542	response to heat
BUM80_RS01540	COG4703	Protein of unknown function (DUF1797)
BUM80_RS01545	COG0765	amino acid transport
BUM80_RS01550	COG1126	abc transporter atp-binding protein
BUM80_RS01555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BUM80_RS01560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BUM80_RS01580	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BUM80_RS01630	COG2813	Specifically methylates the guanine in position
BUM80_RS01635	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BUM80_RS01645	COG0295	cytidine deaminase activity
BUM80_RS01650	COG1744	ABC transporter substrate-binding protein PnrA-like
BUM80_RS01655	COG3845	ABC transporter
BUM80_RS01660	COG4603	Belongs to the binding-protein-dependent transport system permease family
BUM80_RS01665	COG1079	Belongs to the binding-protein-dependent transport system permease family
BUM80_RS01685	COG0187	DNA topoisomerase II activity
BUM80_RS01690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUM80_RS01695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUM80_RS01700	COG4166	transmembrane transport
BUM80_RS01735	COG0539	negative regulation of cytoplasmic translation
BUM80_RS01745	COG1956	GAF domain-containing protein
BUM80_RS01750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BUM80_RS01765	COG0719	Fe-S assembly protein
BUM80_RS01770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BUM80_RS01780	COG0719	Fe-S assembly protein
BUM80_RS01785	COG1686	Belongs to the peptidase S11 family
BUM80_RS01790	COG0628	permease
BUM80_RS01805	COG1349	DNA-binding transcription factor activity
BUM80_RS01810	COG1105	Belongs to the carbohydrate kinase PfkB family
BUM80_RS01815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUM80_RS01815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUM80_RS01815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUM80_RS01820	COG1674	ftsk spoiiie
BUM80_RS01820	COG0697	spore germination
BUM80_RS01830	COG1104	cysteine desulfurase activity
BUM80_RS01885	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BUM80_RS01890	COG1438	arginine binding
BUM80_RS01910	COG0469	pyruvate kinase activity
BUM80_RS01920	COG0582	viral genome integration into host DNA
BUM80_RS01970	COG3689	TIGRFAM TIGR03943 family protein
BUM80_RS01975	COG0701	Predicted permease
BUM80_RS01990	COG2183	response to ionizing radiation
BUM80_RS02010	COG1136	(ABC) transporter
BUM80_RS02015	COG0577	efflux transmembrane transporter activity
BUM80_RS02035	COG1982	Orn Lys Arg decarboxylase major
BUM80_RS02045	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BUM80_RS02065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUM80_RS02070	COG0561	phosphatase activity
BUM80_RS02090	COG0583	DNA-binding transcription factor activity
BUM80_RS02095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BUM80_RS02100	COG0564	pseudouridine synthase activity
BUM80_RS02105	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BUM80_RS02120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUM80_RS02130	COG0470	DNA polymerase III
BUM80_RS02170	COG0528	UMP kinase activity
BUM80_RS02180	COG2996	Protein conserved in bacteria
BUM80_RS02190	COG1702	phosphate starvation-inducible protein PhoH
BUM80_RS02210	COG0686	Belongs to the AlaDH PNT family
BUM80_RS02215	COG0686	Belongs to the AlaDH PNT family
BUM80_RS02220	COG0686	Belongs to the AlaDH PNT family
BUM80_RS02230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUM80_RS02240	COG0658	competence protein
BUM80_RS02240	COG2333	competence protein COMEC
BUM80_RS02250	COG1131	(ABC) transporter
BUM80_RS02280	COG0543	2 iron, 2 sulfur cluster binding
BUM80_RS02285	COG0167	dihydroorotate dehydrogenase activity
BUM80_RS02290	COG4193	domain, Protein
BUM80_RS02290	COG5263	repeat protein
BUM80_RS02295	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BUM80_RS02305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BUM80_RS02315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BUM80_RS02320	COG0237	dephospho-CoA kinase activity
BUM80_RS02325	COG2814	Major facilitator Superfamily
BUM80_RS02330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BUM80_RS02340	COG0557	exoribonuclease II activity
BUM80_RS02350	COG3615	Tellurite resistance protein tehB
BUM80_RS02350	COG0500	methyltransferase
BUM80_RS02365	COG4122	O-methyltransferase activity
BUM80_RS02395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BUM80_RS02415	COG0494	nUDIX hydrolase
BUM80_RS02425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BUM80_RS02435	COG2176	DNA-directed DNA polymerase activity
BUM80_RS02440	COG0584	glycerophosphoryl diester phosphodiesterase
BUM80_RS02460	COG0785	Cytochrome C biogenesis protein
BUM80_RS02465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUM80_RS02470	COG0531	amino acid
BUM80_RS02475	COG0803	Belongs to the bacterial solute-binding protein 9 family
BUM80_RS02475	COG3443	Belongs to the bacterial solute-binding protein 9 family
BUM80_RS02510	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUM80_RS02520	COG1970	mechanosensitive ion channel activity
BUM80_RS02530	COG4708	membrane
BUM80_RS02540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BUM80_RS02555	COG1942	4-Oxalocrotonate Tautomerase
BUM80_RS02560	COG1435	thymidine kinase activity
BUM80_RS02570	COG2890	protein-(glutamine-N5) methyltransferase activity
BUM80_RS02595	COG0741	lytic transglycosylase activity
BUM80_RS02605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUM80_RS02625	COG0772	Belongs to the SEDS family
BUM80_RS02630	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BUM80_RS02645	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BUM80_RS02650	COG0358	DNA primase activity
BUM80_RS02655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BUM80_RS02660	COG2151	metal-sulfur cluster biosynthetic enzyme
BUM80_RS02665	COG0438	transferase activity, transferring glycosyl groups
BUM80_RS02670	COG0438	transferase activity, transferring glycosyl groups
BUM80_RS02695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BUM80_RS02705	COG4109	DRTGG domain
BUM80_RS02710	COG0024	Methionine aminopeptidase
BUM80_RS02725	COG0210	DNA helicase
BUM80_RS02735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BUM80_RS02755	COG1104	cysteine desulfurase activity
BUM80_RS02760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BUM80_RS02770	COG2357	RelA SpoT domain protein
BUM80_RS02780	COG0564	pseudouridine synthase activity
BUM80_RS02785	COG0280	phosphate acetyltransferase
BUM80_RS02845	COG0196	riboflavin kinase activity
BUM80_RS02850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUM80_RS02855	COG1307	EDD domain protein, DegV family
BUM80_RS02865	COG0488	(ABC) transporter
BUM80_RS02885	COG1523	belongs to the glycosyl hydrolase 13 family
BUM80_RS02890	COG1012	belongs to the aldehyde dehydrogenase family
BUM80_RS02900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BUM80_RS02910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BUM80_RS02940	COG0582	viral genome integration into host DNA
BUM80_RS02960	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BUM80_RS02975	COG3583	domain protein
BUM80_RS02975	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BUM80_RS02980	COG3064	Membrane
BUM80_RS03000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BUM80_RS03020	COG0095	Lipoate-protein ligase
BUM80_RS03025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUM80_RS03030	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUM80_RS03035	COG0022	dehydrogenase e1 component
BUM80_RS03040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUM80_RS03045	COG0534	Mate efflux family protein
BUM80_RS03055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BUM80_RS03060	COG1051	belongs to the nudix hydrolase family
BUM80_RS03075	COG1011	Hydrolase
BUM80_RS03080	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BUM80_RS03095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUM80_RS03100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BUM80_RS03105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUM80_RS03110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUM80_RS03145	COG3711	transcriptional antiterminator
BUM80_RS03150	COG3684	Belongs to the aldolase LacD family
BUM80_RS03200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BUM80_RS03205	COG0497	DNA recombination
BUM80_RS03210	COG1438	arginine binding
BUM80_RS03215	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BUM80_RS03250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BUM80_RS03270	COG3764	Sortase (surface protein transpeptidase)
BUM80_RS03275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUM80_RS03285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BUM80_RS03305	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BUM80_RS03310	COG5002	protein histidine kinase activity
BUM80_RS03315	COG0745	RESPONSE REGULATOR receiver
BUM80_RS03320	COG1194	a g-specific adenine glycosylase
BUM80_RS03335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BUM80_RS03340	COG4684	Psort location CytoplasmicMembrane, score
BUM80_RS03350	COG1827	regulation of RNA biosynthetic process
BUM80_RS03355	COG2816	NAD+ diphosphatase activity
BUM80_RS03370	COG0556	nucleotide-excision repair
BUM80_RS03380	COG0765	amino acid transport
BUM80_RS03385	COG1126	abc transporter atp-binding protein
BUM80_RS03390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUM80_RS03395	COG0552	protein localization to endoplasmic reticulum
BUM80_RS03400	COG0561	phosphatase activity
BUM80_RS03405	COG0561	phosphatase activity
BUM80_RS03410	COG1196	nuclear chromosome segregation
BUM80_RS03435	COG1401	restriction endodeoxyribonuclease activity
BUM80_RS03445	COG0066	3-isopropylmalate dehydratase activity
BUM80_RS03470	COG3142	Participates in the control of copper homeostasis
BUM80_RS03475	COG2832	Protein of unknown function (DUF454)
BUM80_RS03480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUM80_RS03490	COG0758	DNA mediated transformation
BUM80_RS03495	COG4750	Nucleotidyl transferase
BUM80_RS03510	COG1063	alcohol dehydrogenase
BUM80_RS03525	COG3475	LICD family
BUM80_RS03530	COG3475	LICD family
BUM80_RS03540	COG0505	Belongs to the CarA family
BUM80_RS03555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BUM80_RS03570	COG0488	(ABC) transporter
BUM80_RS03575	COG0501	Belongs to the peptidase M48B family
BUM80_RS03580	COG1704	LemA family
BUM80_RS03595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BUM80_RS03610	COG1078	dGTPase activity
BUM80_RS03635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUM80_RS03640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUM80_RS03645	COG0077	Prephenate dehydratase
BUM80_RS03645	COG1605	Chorismate mutase
BUM80_RS03650	COG0716	FMN binding
BUM80_RS03655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BUM80_RS03675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUM80_RS03750	COG1674	ftsk spoiiie
BUM80_RS03760	COG2946	Replication initiation factor
BUM80_RS03810	COG0791	NLP P60 protein
BUM80_RS03810	COG0741	lytic transglycosylase activity
BUM80_RS03925	COG0270	DNA (cytosine-5-)-methyltransferase activity
BUM80_RS03955	COG0402	S-adenosylhomocysteine deaminase activity
BUM80_RS03965	COG1132	(ABC) transporter
BUM80_RS03970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUM80_RS03970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUM80_RS04005	COG1215	transferase activity, transferring glycosyl groups
BUM80_RS04015	COG3475	LICD family
BUM80_RS04025	COG0077	Prephenate dehydratase
BUM80_RS04030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BUM80_RS04045	COG0287	Prephenate dehydrogenase
BUM80_RS04070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BUM80_RS04085	COG4555	ABC transporter
BUM80_RS04120	COG1177	transmembrane transport
BUM80_RS04125	COG3842	ATPase activity
BUM80_RS04140	COG3527	Alpha-acetolactate decarboxylase
BUM80_RS04145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUM80_RS04150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUM80_RS04155	COG0704	Plays a role in the regulation of phosphate uptake
BUM80_RS04160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUM80_RS04165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUM80_RS04170	COG0581	inorganic phosphate transmembrane transporter activity
BUM80_RS04175	COG0573	inorganic phosphate transmembrane transporter activity
BUM80_RS04180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BUM80_RS04185	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BUM80_RS04185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BUM80_RS04190	COG0483	inositol monophosphate 1-phosphatase activity
BUM80_RS04200	COG1393	Belongs to the ArsC family
BUM80_RS04210	COG0647	UMP catabolic process
BUM80_RS04220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUM80_RS04240	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BUM80_RS04255	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BUM80_RS04275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BUM80_RS04295	COG1131	(ABC) transporter
BUM80_RS04310	COG0826	peptidase U32
BUM80_RS04340	COG1132	(ABC) transporter
BUM80_RS04345	COG1132	(ABC) transporter
BUM80_RS04360	COG1129	ABC transporter
BUM80_RS04370	COG4372	Transposase
BUM80_RS04405	COG2188	Transcriptional regulator
BUM80_RS04410	COG0697	spore germination
BUM80_RS04415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BUM80_RS04430	COG0561	phosphatase activity
BUM80_RS04465	COG0492	ferredoxin-NADP+ reductase activity
BUM80_RS04475	COG1126	abc transporter atp-binding protein
BUM80_RS04485	COG1393	Belongs to the ArsC family
BUM80_RS04505	COG1272	protein, Hemolysin III
BUM80_RS04535	COG0431	NADPH-dependent FMN reductase
BUM80_RS04535	COG1053	succinate dehydrogenase
BUM80_RS04535	COG3976	FMN-binding domain protein
BUM80_RS04560	COG0656	L-ascorbic acid biosynthetic process
BUM80_RS04565	COG0726	polysaccharide deacetylase
BUM80_RS04600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BUM80_RS04640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUM80_RS04650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUM80_RS04655	COG1126	abc transporter atp-binding protein
BUM80_RS04670	COG0628	permease
BUM80_RS04675	COG2706	6-phosphogluconolactonase activity
BUM80_RS04740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BUM80_RS04765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BUM80_RS04770	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BUM80_RS04775	COG0626	cystathionine gamma-synthase activity
BUM80_RS04780	COG1132	(ABC) transporter
BUM80_RS04785	COG1132	(ABC) transporter
BUM80_RS04790	COG4166	transmembrane transport
BUM80_RS04795	COG2244	polysaccharide biosynthetic process
BUM80_RS04800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BUM80_RS04825	COG2827	Endonuclease containing a URI domain
BUM80_RS04830	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BUM80_RS04835	COG1098	S1 RNA binding domain
BUM80_RS04845	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BUM80_RS04850	COG0629	single-stranded DNA binding
BUM80_RS04865	COG0436	Aminotransferase
BUM80_RS04905	COG0242	peptide deformylase activity
BUM80_RS04910	COG0625	glutathione transferase activity
BUM80_RS04920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUM80_RS04925	COG0488	(ABC) transporter
BUM80_RS04930	COG0617	tRNA 3'-terminal CCA addition
BUM80_RS04940	COG1307	EDD domain protein, DegV family
BUM80_RS04960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUM80_RS04980	COG5263	repeat protein
BUM80_RS04980	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUM80_RS05080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BUM80_RS05255	COG0582	viral genome integration into host DNA
BUM80_RS05260	COG1481	regulation of sporulation
BUM80_RS05265	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BUM80_RS05275	COG0251	oxidation-reduction process
BUM80_RS05295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BUM80_RS05305	COG5263	repeat protein
BUM80_RS05305	COG4193	domain, Protein
BUM80_RS05315	COG3935	DnaD domain protein
BUM80_RS05330	COG2226	methyltransferase
BUM80_RS05335	COG3842	ATPase activity
BUM80_RS05345	COG1335	isochorismatase
BUM80_RS05360	COG0513	Belongs to the DEAD box helicase family
BUM80_RS05365	COG2223	nitrite transmembrane transporter activity
BUM80_RS05370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUM80_RS05375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BUM80_RS05380	COG3442	glutamine amidotransferase
BUM80_RS05385	COG0006	proline dipeptidase activity
BUM80_RS05400	COG4720	Psort location CytoplasmicMembrane, score
BUM80_RS05405	COG0351	phosphomethylpyrimidine kinase
BUM80_RS05430	COG2824	Alkylphosphonate utilization operon protein PhnA
BUM80_RS05450	COG0463	Glycosyl transferase, family 2
BUM80_RS05455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BUM80_RS05460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUM80_RS05465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BUM80_RS05470	COG2384	SAM-dependent methyltransferase
BUM80_RS05475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BUM80_RS05480	COG0204	Acyl-transferase
BUM80_RS05495	COG2910	NAD(P)H-binding
BUM80_RS05530	COG5002	protein histidine kinase activity
BUM80_RS05535	COG0745	RESPONSE REGULATOR receiver
BUM80_RS05550	COG1959	2 iron, 2 sulfur cluster binding
BUM80_RS05585	COG3590	peptidase
BUM80_RS05600	COG0803	Belongs to the bacterial solute-binding protein 9 family
BUM80_RS05605	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BUM80_RS05615	COG1136	(ABC) transporter
BUM80_RS05615	COG0577	efflux transmembrane transporter activity
BUM80_RS05650	COG3599	regulation of cell shape
BUM80_RS05670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BUM80_RS05690	COG1051	belongs to the nudix hydrolase family
BUM80_RS05695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BUM80_RS05710	COG0768	penicillin binding
BUM80_RS05725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BUM80_RS05745	COG2731	YhcH YjgK YiaL family protein
BUM80_RS05750	COG0395	ABC-type sugar transport system, permease component
BUM80_RS05755	COG1175	transmembrane transport
BUM80_RS05765	COG1263	PTS System
BUM80_RS05765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUM80_RS05765	COG2190	(PTS) system
BUM80_RS05775	COG0673	inositol 2-dehydrogenase activity
BUM80_RS05780	COG4409	exo-alpha-(2->6)-sialidase activity
BUM80_RS05790	COG1175	transmembrane transport
BUM80_RS05795	COG1653	transport
BUM80_RS05815	COG3458	cephalosporin-C deacetylase activity
BUM80_RS05830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BUM80_RS05845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BUM80_RS05850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BUM80_RS05855	COG0653	protein targeting
BUM80_RS05865	COG1131	(ABC) transporter
BUM80_RS05895	COG0778	Nitroreductase
BUM80_RS05900	COG1484	DNA-dependent DNA replication
BUM80_RS05915	COG1725	Transcriptional regulator
BUM80_RS05920	COG1131	(ABC) transporter
BUM80_RS05930	COG1668	transmembrane transport
BUM80_RS05935	COG4152	abc transporter atp-binding protein
BUM80_RS05955	COG1940	carbohydrate kinase activity
BUM80_RS05960	COG2190	(PTS) system
BUM80_RS05960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUM80_RS05960	COG1263	PTS System
BUM80_RS05975	COG1621	beta-fructofuranosidase activity
BUM80_RS05980	COG1609	Transcriptional regulator
BUM80_RS05990	COG3425	synthase
BUM80_RS06015	COG2815	serine threonine protein kinase
BUM80_RS06015	COG0515	serine threonine protein kinase
BUM80_RS06020	COG0631	protein serine/threonine phosphatase activity
BUM80_RS06025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BUM80_RS06025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BUM80_RS06035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BUM80_RS06045	COG0194	GDP metabolic process
BUM80_RS06055	COG4115	mRNA cleavage
BUM80_RS06075	COG2226	methyltransferase
BUM80_RS06080	COG0799	negative regulation of ribosome biogenesis
BUM80_RS06090	COG1713	HD superfamily hydrolase involved in NAD metabolism
BUM80_RS06095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BUM80_RS06100	COG1534	Rna-binding protein
BUM80_RS06105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BUM80_RS06120	COG0668	transmembrane transport
BUM80_RS06150	COG3118	belongs to the thioredoxin family
BUM80_RS06155	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BUM80_RS06165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BUM80_RS06180	COG1131	(ABC) transporter
BUM80_RS06185	COG0640	Transcriptional regulator
BUM80_RS06190	COG1164	Oligoendopeptidase f
BUM80_RS06195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BUM80_RS06200	COG2264	protein methyltransferase activity
BUM80_RS06205	COG1051	belongs to the nudix hydrolase family
BUM80_RS06250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BUM80_RS06260	COG1621	beta-fructofuranosidase activity
BUM80_RS06265	COG1653	transport
BUM80_RS06270	COG0395	ABC-type sugar transport system, permease component
BUM80_RS06275	COG4209	transmembrane transport
BUM80_RS06285	COG3711	transcriptional antiterminator
BUM80_RS06290	COG2261	transglycosylase associated protein
BUM80_RS06310	COG3237	CsbD-like
BUM80_RS06325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BUM80_RS06335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUM80_RS06340	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUM80_RS06345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUM80_RS06355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUM80_RS06360	COG1846	Transcriptional regulator
BUM80_RS06360	COG1940	carbohydrate kinase activity
BUM80_RS06370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BUM80_RS06400	COG0135	phosphoribosylanthranilate isomerase activity
BUM80_RS06415	COG0512	Glutamine amidotransferase of anthranilate synthase
BUM80_RS06420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUM80_RS06445	COG1285	pathogenesis
BUM80_RS06450	COG1178	ABC-type Fe3 transport system permease component
BUM80_RS06470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BUM80_RS06475	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BUM80_RS06480	COG0704	Plays a role in the regulation of phosphate uptake
BUM80_RS06490	COG5434	Belongs to the glycosyl hydrolase 28 family
BUM80_RS06500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUM80_RS06505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BUM80_RS06515	COG1132	(ABC) transporter
BUM80_RS06520	COG1132	(ABC) transporter
BUM80_RS06540	COG0708	Exodeoxyribonuclease III
BUM80_RS06560	COG2233	PERMEase
BUM80_RS06585	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BUM80_RS06590	COG1609	Transcriptional regulator
BUM80_RS06595	COG1063	alcohol dehydrogenase
BUM80_RS06600	COG0789	Transcriptional regulator
BUM80_RS06605	COG1230	cation diffusion facilitator family transporter
BUM80_RS06615	COG3201	nicotinamide mononucleotide transporter
BUM80_RS06620	COG1174	glycine betaine transport
BUM80_RS06645	COG1363	Peptidase, m42
BUM80_RS06665	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUM80_RS06670	COG4605	iron ion homeostasis
BUM80_RS06675	COG4604	ABC transporter, ATP-binding protein
BUM80_RS06680	COG4607	ABC-type enterochelin transport system periplasmic component
BUM80_RS06690	COG1187	pseudouridine synthase activity
BUM80_RS06710	COG0517	IMP dehydrogenase activity
BUM80_RS06720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BUM80_RS06735	COG0366	Alpha amylase catalytic
BUM80_RS06745	COG1263	PTS System
BUM80_RS06745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUM80_RS06750	COG2188	Transcriptional regulator
BUM80_RS06755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUM80_RS06770	COG4608	Belongs to the ABC transporter superfamily
BUM80_RS06775	COG0444	Belongs to the ABC transporter superfamily
BUM80_RS06780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUM80_RS06785	COG0601	transmembrane transport
BUM80_RS06790	COG4166	transmembrane transport
BUM80_RS06810	COG0366	Alpha amylase catalytic
BUM80_RS06815	COG0395	ABC-type sugar transport system, permease component
BUM80_RS06825	COG1653	transport
BUM80_RS06830	COG3345	alpha-galactosidase
BUM80_RS06835	COG2207	Transcriptional regulator
BUM80_RS06840	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BUM80_RS06840	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BUM80_RS06955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUM80_RS07000	COG4221	oxidoreductase activity
BUM80_RS07005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUM80_RS07010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUM80_RS07110	COG3842	ATPase activity
BUM80_RS07115	COG1178	ABC-type Fe3 transport system permease component
BUM80_RS07120	COG1285	pathogenesis
BUM80_RS07140	COG5263	repeat protein
BUM80_RS07140	COG5632	N-Acetylmuramoyl-L-alanine amidase
BUM80_RS07160	COG1316	TRANSCRIPTIONal
BUM80_RS07170	COG0802	atpase or kinase
BUM80_RS07200	COG1253	flavin adenine dinucleotide binding
BUM80_RS07215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BUM80_RS07225	COG3480	Lon protease (S16) C-terminal proteolytic domain
BUM80_RS07235	COG0742	ribosomal rna small subunit methyltransferase
BUM80_RS07255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUM80_RS07260	COG1254	Belongs to the acylphosphatase family
BUM80_RS07275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BUM80_RS07285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUM80_RS07305	COG1564	THIamine pyrophosphokinase
BUM80_RS07315	COG1162	GTPase activity
BUM80_RS07350	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BUM80_RS07355	COG0084	hydrolase, TatD family'
BUM80_RS07380	COG0436	Aminotransferase
BUM80_RS07390	COG0589	response to stress
BUM80_RS07395	COG0561	phosphatase activity
BUM80_RS07400	COG0252	asparaginase activity
BUM80_RS07410	COG1609	Transcriptional regulator
BUM80_RS07415	COG2197	response regulator
BUM80_RS07420	COG4585	Histidine kinase
BUM80_RS07425	COG0842	Transport permease protein
BUM80_RS07430	COG1131	(ABC) transporter
BUM80_RS07530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BUM80_RS07535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUM80_RS07540	COG0564	pseudouridine synthase activity
BUM80_RS07550	COG0577	efflux transmembrane transporter activity
BUM80_RS07560	COG0157	Belongs to the NadC ModD family
BUM80_RS07580	COG1129	ABC transporter
BUM80_RS07585	COG2188	Transcriptional regulator
BUM80_RS07590	COG2723	6-phospho-beta-galactosidase activity
BUM80_RS07595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUM80_RS07605	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUM80_RS07610	COG1454	alcohol dehydrogenase
BUM80_RS07610	COG1012	belongs to the aldehyde dehydrogenase family
BUM80_RS07620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BUM80_RS07630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BUM80_RS07650	COG3623	hexulose-6-phosphate isomerase
BUM80_RS07660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUM80_RS07670	COG3037	sugar-specific permease SgaT UlaA
BUM80_RS07680	COG1847	R3H domain protein
BUM80_RS07685	COG0706	membrane insertase activity
BUM80_RS07730	COG4537	Required for transformation and DNA binding
BUM80_RS07735	COG1459	type II secretion system
BUM80_RS07740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BUM80_RS07750	COG1063	alcohol dehydrogenase
BUM80_RS07775	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BUM80_RS07780	COG3759	membrane
BUM80_RS07795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BUM80_RS07795	COG0131	Imidazoleglycerol-phosphate dehydratase
BUM80_RS07800	COG0534	Mate efflux family protein
BUM80_RS07915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BUM80_RS07920	COG1132	(ABC) transporter
BUM80_RS07930	COG1132	(ABC) transporter
BUM80_RS07940	COG1438	arginine binding
BUM80_RS07965	COG0745	RESPONSE REGULATOR receiver
BUM80_RS07970	COG5002	protein histidine kinase activity
BUM80_RS07975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BUM80_RS07980	COG0573	inorganic phosphate transmembrane transporter activity
BUM80_RS07990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUM80_RS07995	COG0704	Plays a role in the regulation of phosphate uptake
BUM80_RS08015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUM80_RS08025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BUM80_RS08040	COG0697	spore germination
BUM80_RS08055	COG2217	Heavy metal translocating P-type atpase
BUM80_RS08065	COG2226	methyltransferase
BUM80_RS08085	COG0058	SHG alpha-glucan phosphorylase activity
BUM80_RS08090	COG1640	4-alpha-glucanotransferase
BUM80_RS08095	COG2182	Extracellular solute-binding protein
BUM80_RS08100	COG1175	transmembrane transport
BUM80_RS08105	COG3833	ABC-type maltose transport systems, permease component
BUM80_RS08110	COG5521	maltodextrose utilization protein MalA
BUM80_RS08115	COG1609	Transcriptional regulator
BUM80_RS08125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUM80_RS08130	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BUM80_RS08160	COG1476	TRANSCRIPTIONal
BUM80_RS08195	COG2151	metal-sulfur cluster biosynthetic enzyme
BUM80_RS08210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BUM80_RS08215	COG3959	Transketolase, thiamine diphosphate binding domain
BUM80_RS08230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUM80_RS08250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BUM80_RS08280	COG0383	alpha-mannosidase activity
BUM80_RS08290	COG3537	Alpha-1,2-mannosidase
BUM80_RS08315	COG0549	Belongs to the carbamate kinase family
BUM80_RS08320	COG1288	antiporter activity
BUM80_RS08325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUM80_RS08335	COG3064	Membrane
BUM80_RS08335	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUM80_RS08335	COG3583	domain protein
BUM80_RS08350	COG1454	alcohol dehydrogenase
BUM80_RS08355	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
BUM80_RS08370	COG3716	PTS system mannose fructose sorbose family IID component
BUM80_RS08380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUM80_RS08400	COG1070	Carbohydrate kinase
BUM80_RS08410	COG3443	Belongs to the bacterial solute-binding protein 9 family
BUM80_RS08410	COG0803	Belongs to the bacterial solute-binding protein 9 family
BUM80_RS08415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BUM80_RS08420	COG1121	(ABC) transporter
BUM80_RS08425	COG1846	Transcriptional regulator
BUM80_RS08430	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BUM80_RS08440	COG1696	Membrane protein involved in D-alanine export
BUM80_RS08455	COG2211	Major facilitator Superfamily
BUM80_RS08465	COG3344	reverse transcriptase
BUM80_RS08495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BUM80_RS08500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BUM80_RS08520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BUM80_RS08530	COG1755	Isoprenylcysteine carboxyl methyltransferase
BUM80_RS08535	COG5002	protein histidine kinase activity
BUM80_RS08540	COG0745	RESPONSE REGULATOR receiver
BUM80_RS08550	COG0542	response to heat
BUM80_RS08555	COG4463	regulation of RNA biosynthetic process
BUM80_RS08560	COG1116	anion transmembrane transporter activity
BUM80_RS08565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUM80_RS08570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUM80_RS08590	COG0305	Participates in initiation and elongation during chromosome replication
BUM80_RS08610	COG1040	competence protein
BUM80_RS08615	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BUM80_RS08620	COG1739	Uncharacterized protein family UPF0029
BUM80_RS08660	COG3942	CHAP domain
BUM80_RS08670	COG1792	Involved in formation and maintenance of cell shape
BUM80_RS08675	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BUM80_RS08680	COG1122	ATPase activity
BUM80_RS08685	COG1122	ATPase activity
BUM80_RS08690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BUM80_RS08700	COG0612	Peptidase, M16
BUM80_RS08705	COG0612	Peptidase, M16
BUM80_RS08710	COG2501	S4 domain
BUM80_RS08720	COG0517	IMP dehydrogenase activity
BUM80_RS08720	COG0516	GMP reductase activity
BUM80_RS08725	COG0180	Tryptophanyl-tRNA synthetase
BUM80_RS08730	COG0488	(ABC) transporter
BUM80_RS08740	COG1511	domain protein
BUM80_RS08740	COG1511	domain protein
BUM80_RS08785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUM80_RS08790	COG1475	DNA binding
BUM80_RS08800	COG0592	DNA-directed DNA polymerase activity
BUM80_RS08905	COG4974	Belongs to the 'phage' integrase family
BUM80_RS08910	COG0012	GTP binding
BUM80_RS08920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BUM80_RS08925	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BUM80_RS08945	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BUM80_RS08950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BUM80_RS09020	COG0756	dUTP diphosphatase activity
BUM80_RS09030	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BUM80_RS09045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BUM80_RS09070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUM80_RS09070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUM80_RS09075	COG1832	CoA-binding protein
BUM80_RS09080	COG2855	membrane
BUM80_RS09085	COG0436	Aminotransferase
BUM80_RS09100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUM80_RS09140	COG1134	teichoic acid transport
BUM80_RS09140	COG1388	LysM domain
BUM80_RS09150	COG2274	protein secretion by the type I secretion system
BUM80_RS09155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUM80_RS09170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BUM80_RS09175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BUM80_RS09185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BUM80_RS09200	COG0151	Belongs to the GarS family
BUM80_RS09215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BUM80_RS09230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BUM80_RS09235	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUM80_RS09235	COG3583	domain protein
BUM80_RS09235	COG3064	Membrane
BUM80_RS09250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUM80_RS09255	COG3715	PTS system
BUM80_RS09260	COG3716	PTS system mannose fructose sorbose family IID component
BUM80_RS09270	COG2222	sugar isomerase
BUM80_RS09280	COG2514	catechol 2,3-dioxygenase activity
BUM80_RS09285	COG1937	Protein conserved in bacteria
BUM80_RS09325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUM80_RS09330	COG0569	domain protein
BUM80_RS09340	COG1215	transferase activity, transferring glycosyl groups
BUM80_RS09360	COG5002	protein histidine kinase activity
BUM80_RS09385	COG4209	transmembrane transport
BUM80_RS09390	COG0395	ABC-type sugar transport system, permease component
BUM80_RS09400	COG1653	transport
BUM80_RS09435	COG1695	Transcriptional regulator
BUM80_RS09455	COG0546	phosphoglycolate phosphatase activity
BUM80_RS09460	COG1760	l-serine dehydratase
BUM80_RS09465	COG1760	l-serine dehydratase
BUM80_RS09470	COG1705	Flagellar rod assembly protein muramidase FlgJ
BUM80_RS09470	COG1388	LysM domain
BUM80_RS09505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUM80_RS09510	COG0137	argininosuccinate synthase activity
BUM80_RS09525	COG2274	protein secretion by the type I secretion system
BUM80_RS09625	COG0494	nUDIX hydrolase
BUM80_RS09630	COG0445	tRNA wobble uridine modification
BUM80_RS09665	COG1214	PFAM Peptidase M22, glycoprotease
BUM80_RS09705	COG0438	transferase activity, transferring glycosyl groups
BUM80_RS09740	COG1396	sequence-specific DNA binding
BUM80_RS09770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUM80_RS09775	COG1464	Belongs to the NlpA lipoprotein family
BUM80_RS09780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUM80_RS09785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUM80_RS09805	COG2972	Histidine kinase
BUM80_RS09810	COG2207	Transcriptional regulator
BUM80_RS09810	COG4753	response regulator
BUM80_RS09820	COG1780	Probably involved in ribonucleotide reductase function
BUM80_RS09850	COG2818	Glycosylase
BUM80_RS09875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BUM80_RS09880	COG0006	proline dipeptidase activity
BUM80_RS09890	COG1393	Belongs to the ArsC family
BUM80_RS09915	COG0285	dihydrofolate synthase activity
BUM80_RS09925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUM80_RS09955	COG0602	queuosine metabolic process
BUM80_RS09990	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BUM80_RS10015	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BUM80_RS10055	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BUM80_RS10070	COG0201	protein transport
BUM80_RS10080	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BUM80_RS10085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BUM80_RS10095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BUM80_RS10100	COG0202	RNA polymerase activity
BUM80_RS10110	COG3830	Belongs to the UPF0237 family
BUM80_RS10130	COG1178	ABC-type Fe3 transport system permease component
BUM80_RS10150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BUM80_RS10155	COG1349	DNA-binding transcription factor activity
BUM80_RS10165	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUM80_RS10170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUM80_RS10175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUM80_RS10180	COG1882	Formate acetyltransferase
BUM80_RS10225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BUM80_RS10230	COG4589	Belongs to the CDS family
BUM80_RS10235	COG0750	zinc metalloprotease
BUM80_RS10245	COG2723	6-phospho-beta-galactosidase activity
BUM80_RS10250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BUM80_RS10265	COG1523	belongs to the glycosyl hydrolase 13 family
BUM80_RS10295	COG2176	DNA-directed DNA polymerase activity
BUM80_RS10315	COG2309	aminopeptidase activity
BUM80_RS10320	COG2261	transglycosylase associated protein
BUM80_RS10325	COG1187	pseudouridine synthase activity
BUM80_RS10335	COG3579	cysteine-type endopeptidase activity
BUM80_RS10340	COG3716	PTS system mannose fructose sorbose family IID component
BUM80_RS10345	COG3715	PTS system
BUM80_RS10355	COG1064	alcohol dehydrogenase
BUM80_RS10360	COG0561	phosphatase activity
BUM80_RS10365	COG2252	PERMEase
BUM80_RS10375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BUM80_RS10380	COG0285	dihydrofolate synthase activity
BUM80_RS10390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BUM80_RS10390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BUM80_RS10405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BUM80_RS10435	COG0386	Belongs to the glutathione peroxidase family
BUM80_RS10440	COG5492	domain, Protein
BUM80_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
BUM80_RS10480	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BUM80_RS10485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUM80_RS10490	COG3715	PTS system
BUM80_RS10495	COG3716	PTS system mannose fructose sorbose family IID component
BUM80_RS10510	COG1609	Transcriptional regulator
BUM80_RS10535	COG4839	cell division protein FtsL
BUM80_RS10540	COG0768	penicillin binding
BUM80_RS10570	COG0366	Alpha amylase catalytic
BUM80_RS10575	COG4166	transmembrane transport
BUM80_RS10590	COG4464	protein tyrosine phosphatase activity
BUM80_RS10595	COG3944	biosynthesis protein
BUM80_RS10600	COG0489	protein tyrosine kinase activity
BUM80_RS10610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BUM80_RS10620	COG0438	transferase activity, transferring glycosyl groups
BUM80_RS10625	COG3955	Domain of unknown function (DUF1919)
BUM80_RS10645	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BUM80_RS10655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BUM80_RS10660	COG3594	Acyltransferase
BUM80_RS10665	COG4166	transmembrane transport
BUM80_RS10675	COG0366	Alpha amylase catalytic
BUM80_RS10705	COG0116	Belongs to the methyltransferase superfamily
BUM80_RS10715	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BUM80_RS10720	COG0745	RESPONSE REGULATOR receiver
BUM80_RS10780	COG4585	Histidine kinase
BUM80_RS10785	COG2197	response regulator
BUM80_RS10815	COG0582	viral genome integration into host DNA
BUM80_RS10825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BUM80_RS10830	COG0681	Belongs to the peptidase S26 family
BUM80_RS10850	COG1193	negative regulation of DNA recombination
BUM80_RS10855	COG1115	amino acid carrier protein
BUM80_RS10880	COG0527	aspartate kinase activity
BUM80_RS10890	COG1024	Enoyl-CoA hydratase
BUM80_RS10895	COG1846	Transcriptional regulator
BUM80_RS10905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUM80_RS10915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BUM80_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
BUM80_RS10925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUM80_RS10940	COG0439	Biotin carboxylase
BUM80_RS10945	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BUM80_RS11015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BUM80_RS11025	COG1461	Dihydroxyacetone kinase
BUM80_RS11030	COG0028	Belongs to the TPP enzyme family
BUM80_RS11035	COG0440	acetolactate synthase activity
BUM80_RS11055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BUM80_RS11075	COG0765	amino acid transport
BUM80_RS11105	COG1882	Formate acetyltransferase
BUM80_RS11170	COG1940	carbohydrate kinase activity
BUM80_RS11170	COG1846	Transcriptional regulator
BUM80_RS11175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUM80_RS11185	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUM80_RS11190	COG2723	6-phospho-beta-galactosidase activity
BUM80_RS11195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUM80_RS11195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUM80_RS11200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUM80_RS11205	COG0569	domain protein
BUM80_RS11220	COG1122	ATPase activity
BUM80_RS11235	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BUM80_RS11240	COG0671	phosphoesterase, PA-phosphatase related
BUM80_RS11260	COG0504	CTP synthase activity
BUM80_RS11265	COG1283	sodium-dependent phosphate transmembrane transporter activity