locus-tag	class	description
J4Q30_RS00010	COG0592	DNA-directed DNA polymerase activity
J4Q30_RS00170	COG3645	SOS response
J4Q30_RS00175	COG4974	Belongs to the 'phage' integrase family
J4Q30_RS00180	COG0012	GTP binding
J4Q30_RS00190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4Q30_RS00195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4Q30_RS00215	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J4Q30_RS00220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4Q30_RS00420	COG0582	viral genome integration into host DNA
J4Q30_RS00535	COG5263	repeat protein
J4Q30_RS00535	COG5632	N-Acetylmuramoyl-L-alanine amidase
J4Q30_RS00560	COG0756	dUTP diphosphatase activity
J4Q30_RS00570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4Q30_RS00585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4Q30_RS00600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4Q30_RS00600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4Q30_RS00605	COG1832	CoA-binding protein
J4Q30_RS00615	COG2855	membrane
J4Q30_RS00620	COG0436	Aminotransferase
J4Q30_RS00625	COG1381	Involved in DNA repair and RecF pathway recombination
J4Q30_RS00635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4Q30_RS00650	COG2274	protein secretion by the type I secretion system
J4Q30_RS00655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4Q30_RS00665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4Q30_RS00670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4Q30_RS00680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4Q30_RS00695	COG0151	Belongs to the GarS family
J4Q30_RS00705	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4Q30_RS00720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4Q30_RS00725	COG3583	domain protein
J4Q30_RS00725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J4Q30_RS00725	COG3064	Membrane
J4Q30_RS00740	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4Q30_RS00745	COG3715	PTS system
J4Q30_RS00750	COG3716	PTS system mannose fructose sorbose family IID component
J4Q30_RS00760	COG2222	sugar isomerase
J4Q30_RS00770	COG2514	catechol 2,3-dioxygenase activity
J4Q30_RS00775	COG1937	Protein conserved in bacteria
J4Q30_RS00805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4Q30_RS00810	COG0569	domain protein
J4Q30_RS00820	COG1215	transferase activity, transferring glycosyl groups
J4Q30_RS00840	COG5002	protein histidine kinase activity
J4Q30_RS00865	COG4209	transmembrane transport
J4Q30_RS00870	COG0395	ABC-type sugar transport system, permease component
J4Q30_RS00875	COG1653	transport
J4Q30_RS00900	COG0577	efflux transmembrane transporter activity
J4Q30_RS00900	COG1136	(ABC) transporter
J4Q30_RS00920	COG1695	Transcriptional regulator
J4Q30_RS00945	COG0546	phosphoglycolate phosphatase activity
J4Q30_RS00950	COG1760	l-serine dehydratase
J4Q30_RS00955	COG1760	l-serine dehydratase
J4Q30_RS00960	COG1388	LysM domain
J4Q30_RS00960	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4Q30_RS00985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4Q30_RS01095	COG0494	nUDIX hydrolase
J4Q30_RS01100	COG0445	tRNA wobble uridine modification
J4Q30_RS01135	COG1214	PFAM Peptidase M22, glycoprotease
J4Q30_RS01170	COG0438	transferase activity, transferring glycosyl groups
J4Q30_RS01200	COG1396	sequence-specific DNA binding
J4Q30_RS01235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4Q30_RS01240	COG1464	Belongs to the NlpA lipoprotein family
J4Q30_RS01245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4Q30_RS01250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4Q30_RS01270	COG2972	Histidine kinase
J4Q30_RS01275	COG2207	Transcriptional regulator
J4Q30_RS01275	COG4753	response regulator
J4Q30_RS01285	COG1780	Probably involved in ribonucleotide reductase function
J4Q30_RS01315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4Q30_RS01315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4Q30_RS01335	COG2818	Glycosylase
J4Q30_RS01440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4Q30_RS01445	COG0006	proline dipeptidase activity
J4Q30_RS01450	COG1393	Belongs to the ArsC family
J4Q30_RS01475	COG0285	dihydrofolate synthase activity
J4Q30_RS01485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4Q30_RS01550	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J4Q30_RS01575	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J4Q30_RS01615	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J4Q30_RS01630	COG0201	protein transport
J4Q30_RS01640	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4Q30_RS01645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4Q30_RS01655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J4Q30_RS01660	COG0202	RNA polymerase activity
J4Q30_RS01670	COG3830	Belongs to the UPF0237 family
J4Q30_RS01705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4Q30_RS01710	COG1349	DNA-binding transcription factor activity
J4Q30_RS01720	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4Q30_RS01725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4Q30_RS01730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4Q30_RS01735	COG1882	Formate acetyltransferase
J4Q30_RS01785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4Q30_RS01790	COG4589	Belongs to the CDS family
J4Q30_RS01795	COG0750	zinc metalloprotease
J4Q30_RS01805	COG2723	6-phospho-beta-galactosidase activity
J4Q30_RS01810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4Q30_RS01825	COG1523	belongs to the glycosyl hydrolase 13 family
J4Q30_RS01845	COG2176	DNA-directed DNA polymerase activity
J4Q30_RS01865	COG2309	aminopeptidase activity
J4Q30_RS01870	COG2261	transglycosylase associated protein
J4Q30_RS01875	COG1187	pseudouridine synthase activity
J4Q30_RS01880	COG3579	cysteine-type endopeptidase activity
J4Q30_RS01885	COG3716	PTS system mannose fructose sorbose family IID component
J4Q30_RS01890	COG3715	PTS system
J4Q30_RS01900	COG1064	alcohol dehydrogenase
J4Q30_RS01905	COG0561	phosphatase activity
J4Q30_RS01910	COG2252	PERMEase
J4Q30_RS01925	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4Q30_RS01930	COG0285	dihydrofolate synthase activity
J4Q30_RS01940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4Q30_RS01940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4Q30_RS01950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J4Q30_RS01975	COG0386	Belongs to the glutathione peroxidase family
J4Q30_RS02010	COG4839	cell division protein FtsL
J4Q30_RS02015	COG0768	penicillin binding
J4Q30_RS02040	COG0366	Alpha amylase catalytic
J4Q30_RS02045	COG4166	transmembrane transport
J4Q30_RS02060	COG4464	protein tyrosine phosphatase activity
J4Q30_RS02065	COG3944	biosynthesis protein
J4Q30_RS02070	COG0489	protein tyrosine kinase activity
J4Q30_RS02085	COG3475	LICD family
J4Q30_RS02105	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4Q30_RS02110	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J4Q30_RS02120	COG1088	dTDP-glucose 4,6-dehydratase activity
J4Q30_RS02125	COG1091	dTDP-4-dehydrorhamnose reductase activity
J4Q30_RS02135	COG4166	transmembrane transport
J4Q30_RS02140	COG0366	Alpha amylase catalytic
J4Q30_RS02145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4Q30_RS02170	COG0116	Belongs to the methyltransferase superfamily
J4Q30_RS02180	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4Q30_RS02185	COG0745	RESPONSE REGULATOR receiver
J4Q30_RS02250	COG4585	Histidine kinase
J4Q30_RS02255	COG2197	response regulator
J4Q30_RS02275	COG0582	viral genome integration into host DNA
J4Q30_RS02285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4Q30_RS02290	COG0681	Belongs to the peptidase S26 family
J4Q30_RS02315	COG1115	amino acid carrier protein
J4Q30_RS02340	COG0527	aspartate kinase activity
J4Q30_RS02345	COG1024	Enoyl-CoA hydratase
J4Q30_RS02350	COG1846	Transcriptional regulator
J4Q30_RS02360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4Q30_RS02370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J4Q30_RS02375	COG1028	Short-chain dehydrogenase reductase Sdr
J4Q30_RS02380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4Q30_RS02395	COG0439	Biotin carboxylase
J4Q30_RS02400	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4Q30_RS02445	COG1063	alcohol dehydrogenase
J4Q30_RS02470	COG1442	glycosyl transferase family 8
J4Q30_RS02475	COG1442	glycosyl transferase family 8
J4Q30_RS02480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J4Q30_RS02490	COG1461	Dihydroxyacetone kinase
J4Q30_RS02495	COG0028	Belongs to the TPP enzyme family
J4Q30_RS02500	COG0440	acetolactate synthase activity
J4Q30_RS02520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J4Q30_RS02535	COG0765	amino acid transport
J4Q30_RS02555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4Q30_RS02560	COG1882	Formate acetyltransferase
J4Q30_RS02575	COG1940	carbohydrate kinase activity
J4Q30_RS02575	COG1846	Transcriptional regulator
J4Q30_RS02580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4Q30_RS02590	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4Q30_RS02595	COG2723	6-phospho-beta-galactosidase activity
J4Q30_RS02600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4Q30_RS02600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4Q30_RS02605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4Q30_RS02610	COG0569	domain protein
J4Q30_RS02630	COG1122	ATPase activity
J4Q30_RS02645	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
J4Q30_RS02650	COG0671	phosphoesterase, PA-phosphatase related
J4Q30_RS02660	COG1247	-acetyltransferase
J4Q30_RS02670	COG0504	CTP synthase activity
J4Q30_RS02675	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4Q30_RS02695	COG0789	Transcriptional regulator
J4Q30_RS02700	COG0174	glutamine synthetase
J4Q30_RS02720	COG0732	type I restriction modification DNA specificity domain
J4Q30_RS02760	COG0484	heat shock protein binding
J4Q30_RS02775	COG0537	adenosine 5'-monophosphoramidase activity
J4Q30_RS02780	COG1131	(ABC) transporter
J4Q30_RS02785	COG4473	ABC transporter
J4Q30_RS02805	COG3290	protein histidine kinase activity
J4Q30_RS02820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4Q30_RS02890	COG1266	CAAX protease self-immunity
J4Q30_RS02910	COG0195	Participates in both transcription termination and antitermination
J4Q30_RS02915	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J4Q30_RS02980	COG0519	Catalyzes the synthesis of GMP from XMP
J4Q30_RS02990	COG0525	valine-tRNA ligase activity
J4Q30_RS03020	COG3711	transcriptional antiterminator
J4Q30_RS03040	COG0456	acetyltransferase
J4Q30_RS03045	COG0072	phenylalanine-tRNA ligase activity
J4Q30_RS03045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4Q30_RS03060	COG3620	sequence-specific DNA binding
J4Q30_RS03070	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4Q30_RS03080	COG1045	serine acetyltransferase
J4Q30_RS03090	COG0215	cysteine-tRNA ligase activity
J4Q30_RS03095	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
J4Q30_RS03115	COG0577	efflux transmembrane transporter activity
J4Q30_RS03120	COG1136	(ABC) transporter
J4Q30_RS03125	COG0577	efflux transmembrane transporter activity
J4Q30_RS03135	COG0745	RESPONSE REGULATOR receiver
J4Q30_RS03140	COG5002	protein histidine kinase activity
J4Q30_RS03145	COG0191	fructose-bisphosphate aldolase activity
J4Q30_RS03150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4Q30_RS03155	COG0765	amino acid transport
J4Q30_RS03160	COG0765	amino acid transport
J4Q30_RS03165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4Q30_RS03175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4Q30_RS03175	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J4Q30_RS03215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4Q30_RS03230	COG1573	uracil-dna glycosylase
J4Q30_RS03240	COG1114	Component of the transport system for branched-chain amino acids
J4Q30_RS03245	COG1363	Peptidase, m42
J4Q30_RS03280	COG4555	ABC transporter
J4Q30_RS03300	COG1404	Belongs to the peptidase S8 family
J4Q30_RS03315	COG3775	system Galactitol-specific IIC component
J4Q30_RS03320	COG3250	beta-galactosidase activity
J4Q30_RS03350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J4Q30_RS03370	COG0785	Cytochrome C biogenesis protein
J4Q30_RS03375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4Q30_RS03380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4Q30_RS03380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4Q30_RS03385	COG2207	Transcriptional regulator
J4Q30_RS03385	COG4753	response regulator
J4Q30_RS03390	COG2972	Histidine kinase
J4Q30_RS03400	COG3064	Membrane
J4Q30_RS03405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4Q30_RS03420	COG1940	carbohydrate kinase activity
J4Q30_RS03440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4Q30_RS03445	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J4Q30_RS03455	COG0300	oxidoreductase activity
J4Q30_RS03470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4Q30_RS03480	COG1187	pseudouridine synthase activity
J4Q30_RS03485	COG1217	gtp-binding protein TYPA
J4Q30_RS03505	COG1136	(ABC) transporter
J4Q30_RS03520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4Q30_RS03530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4Q30_RS03550	COG1131	(ABC) transporter
J4Q30_RS03555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4Q30_RS03590	COG1304	FMN binding
J4Q30_RS03600	COG1304	FMN binding
J4Q30_RS03615	COG0352	thiamine-phosphate diphosphorylase activity
J4Q30_RS03625	COG4172	Belongs to the ABC transporter superfamily
J4Q30_RS03635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4Q30_RS03650	COG0352	thiamine-phosphate diphosphorylase activity
J4Q30_RS03670	COG2217	Heavy metal translocating P-type atpase
J4Q30_RS03675	COG0028	Belongs to the TPP enzyme family
J4Q30_RS03700	COG1482	cell wall glycoprotein biosynthetic process
J4Q30_RS03705	COG0733	neurotransmitter:sodium symporter activity
J4Q30_RS03720	COG2081	HI0933 family
J4Q30_RS03725	COG1307	EDD domain protein, DegV family
J4Q30_RS03735	COG2131	deaminase
J4Q30_RS03740	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4Q30_RS03780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4Q30_RS03780	COG0617	tRNA 3'-terminal CCA addition
J4Q30_RS03780	COG0517	IMP dehydrogenase activity
J4Q30_RS03790	COG2884	Cell division ATP-binding protein ftsE
J4Q30_RS03795	COG2177	Part of the ABC transporter FtsEX involved in
J4Q30_RS03800	COG2190	(PTS) system
J4Q30_RS03800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4Q30_RS03800	COG1263	PTS System
J4Q30_RS03810	COG0513	Belongs to the DEAD box helicase family
J4Q30_RS03820	COG0167	dihydroorotate dehydrogenase activity
J4Q30_RS03830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4Q30_RS03835	COG4470	Protein conserved in bacteria
J4Q30_RS03850	COG0488	(ABC) transporter
J4Q30_RS03875	COG1837	Belongs to the UPF0109 family
J4Q30_RS03890	COG0513	Belongs to the DEAD box helicase family
J4Q30_RS03905	COG0726	polysaccharide deacetylase
J4Q30_RS03910	COG0656	L-ascorbic acid biosynthetic process
J4Q30_RS03935	COG0431	NADPH-dependent FMN reductase
J4Q30_RS03935	COG1053	succinate dehydrogenase
J4Q30_RS03935	COG3976	FMN-binding domain protein
J4Q30_RS03965	COG1272	protein, Hemolysin III
J4Q30_RS03980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4Q30_RS03985	COG1393	Belongs to the ArsC family
J4Q30_RS03995	COG1126	abc transporter atp-binding protein
J4Q30_RS04005	COG0492	ferredoxin-NADP+ reductase activity
J4Q30_RS04030	COG0561	phosphatase activity
J4Q30_RS04045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4Q30_RS04050	COG0697	spore germination
J4Q30_RS04055	COG2188	Transcriptional regulator
J4Q30_RS04075	COG1132	(ABC) transporter
J4Q30_RS04080	COG1132	(ABC) transporter
J4Q30_RS04095	COG1129	ABC transporter
J4Q30_RS04115	COG0826	peptidase U32
J4Q30_RS04130	COG1131	(ABC) transporter
J4Q30_RS04150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J4Q30_RS04160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4Q30_RS04175	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J4Q30_RS04210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4Q30_RS04220	COG0647	UMP catabolic process
J4Q30_RS04230	COG1393	Belongs to the ArsC family
J4Q30_RS04240	COG0483	inositol monophosphate 1-phosphatase activity
J4Q30_RS04245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4Q30_RS04245	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J4Q30_RS04250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4Q30_RS04255	COG0573	inorganic phosphate transmembrane transporter activity
J4Q30_RS04260	COG0581	inorganic phosphate transmembrane transporter activity
J4Q30_RS04265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4Q30_RS04270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4Q30_RS04275	COG0704	Plays a role in the regulation of phosphate uptake
J4Q30_RS04280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4Q30_RS04285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4Q30_RS04290	COG3527	Alpha-acetolactate decarboxylase
J4Q30_RS04305	COG3842	ATPase activity
J4Q30_RS04345	COG1131	(ABC) transporter
J4Q30_RS04355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4Q30_RS04380	COG0287	Prephenate dehydrogenase
J4Q30_RS04395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J4Q30_RS04400	COG0077	Prephenate dehydratase
J4Q30_RS04410	COG3475	LICD family
J4Q30_RS04420	COG1215	transferase activity, transferring glycosyl groups
J4Q30_RS04455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4Q30_RS04455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4Q30_RS04460	COG1132	(ABC) transporter
J4Q30_RS04470	COG0402	S-adenosylhomocysteine deaminase activity
J4Q30_RS04515	COG1737	Transcriptional regulator
J4Q30_RS04520	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
J4Q30_RS04525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4Q30_RS04530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4Q30_RS04540	COG4409	exo-alpha-(2->6)-sialidase activity
J4Q30_RS04545	COG0673	inositol 2-dehydrogenase activity
J4Q30_RS04560	COG1269	ATP hydrolysis coupled proton transport
J4Q30_RS04565	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J4Q30_RS04640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4Q30_RS04665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4Q30_RS04670	COG0716	FMN binding
J4Q30_RS04675	COG0077	Prephenate dehydratase
J4Q30_RS04675	COG1605	Chorismate mutase
J4Q30_RS04680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4Q30_RS04685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4Q30_RS04710	COG1078	dGTPase activity
J4Q30_RS04725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4Q30_RS04740	COG1704	LemA family
J4Q30_RS04750	COG0488	(ABC) transporter
J4Q30_RS04760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4Q30_RS04775	COG0505	Belongs to the CarA family
J4Q30_RS04785	COG3475	LICD family
J4Q30_RS04790	COG3475	LICD family
J4Q30_RS04800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4Q30_RS04805	COG1063	alcohol dehydrogenase
J4Q30_RS04820	COG4750	Nucleotidyl transferase
J4Q30_RS04825	COG0758	DNA mediated transformation
J4Q30_RS04835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4Q30_RS04840	COG2832	Protein of unknown function (DUF454)
J4Q30_RS04845	COG3142	Participates in the control of copper homeostasis
J4Q30_RS04865	COG0473	3-isopropylmalate dehydrogenase activity
J4Q30_RS04875	COG0066	3-isopropylmalate dehydratase activity
J4Q30_RS04885	COG1401	restriction endodeoxyribonuclease activity
J4Q30_RS04910	COG1196	nuclear chromosome segregation
J4Q30_RS04915	COG0561	phosphatase activity
J4Q30_RS04920	COG0561	phosphatase activity
J4Q30_RS04925	COG0552	protein localization to endoplasmic reticulum
J4Q30_RS04930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4Q30_RS04935	COG1126	abc transporter atp-binding protein
J4Q30_RS04940	COG0765	amino acid transport
J4Q30_RS04965	COG2816	NAD+ diphosphatase activity
J4Q30_RS04970	COG1827	regulation of RNA biosynthetic process
J4Q30_RS04980	COG4684	Psort location CytoplasmicMembrane, score
J4Q30_RS04985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4Q30_RS05000	COG1194	a g-specific adenine glycosylase
J4Q30_RS05005	COG0745	RESPONSE REGULATOR receiver
J4Q30_RS05010	COG5002	protein histidine kinase activity
J4Q30_RS05015	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J4Q30_RS05030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4Q30_RS05045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4Q30_RS05050	COG3764	Sortase (surface protein transpeptidase)
J4Q30_RS05070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J4Q30_RS05100	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J4Q30_RS05105	COG1438	arginine binding
J4Q30_RS05110	COG0497	DNA recombination
J4Q30_RS05115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J4Q30_RS05165	COG3684	Belongs to the aldolase LacD family
J4Q30_RS05170	COG3711	transcriptional antiterminator
J4Q30_RS05185	COG2723	6-phospho-beta-galactosidase activity
J4Q30_RS05200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4Q30_RS05205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4Q30_RS05210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4Q30_RS05215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4Q30_RS05230	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
J4Q30_RS05235	COG1011	Hydrolase
J4Q30_RS05250	COG1051	belongs to the nudix hydrolase family
J4Q30_RS05255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4Q30_RS05265	COG0534	Mate efflux family protein
J4Q30_RS05270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J4Q30_RS05275	COG0022	dehydrogenase e1 component
J4Q30_RS05280	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4Q30_RS05285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4Q30_RS05290	COG0095	Lipoate-protein ligase
J4Q30_RS05310	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4Q30_RS05315	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J4Q30_RS05315	COG3583	domain protein
J4Q30_RS05370	COG0560	Phosphoserine phosphatase
J4Q30_RS05375	COG0560	Phosphoserine phosphatase
J4Q30_RS05385	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4Q30_RS05395	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4Q30_RS05400	COG1012	belongs to the aldehyde dehydrogenase family
J4Q30_RS05405	COG1523	belongs to the glycosyl hydrolase 13 family
J4Q30_RS05425	COG0488	(ABC) transporter
J4Q30_RS05435	COG1307	EDD domain protein, DegV family
J4Q30_RS05440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4Q30_RS05445	COG0196	riboflavin kinase activity
J4Q30_RS05485	COG0280	phosphate acetyltransferase
J4Q30_RS05490	COG0564	pseudouridine synthase activity
J4Q30_RS05500	COG2357	RelA SpoT domain protein
J4Q30_RS05510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4Q30_RS05515	COG1104	cysteine desulfurase activity
J4Q30_RS05535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J4Q30_RS05545	COG0210	DNA helicase
J4Q30_RS05555	COG0024	Methionine aminopeptidase
J4Q30_RS05560	COG4109	DRTGG domain
J4Q30_RS05570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4Q30_RS05600	COG0438	transferase activity, transferring glycosyl groups
J4Q30_RS05605	COG0438	transferase activity, transferring glycosyl groups
J4Q30_RS05610	COG2151	metal-sulfur cluster biosynthetic enzyme
J4Q30_RS05615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4Q30_RS05620	COG0358	DNA primase activity
J4Q30_RS05640	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J4Q30_RS05645	COG0772	Belongs to the SEDS family
J4Q30_RS05680	COG1597	lipid kinase activity
J4Q30_RS05755	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4Q30_RS05760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4Q30_RS05775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4Q30_RS05785	COG0741	lytic transglycosylase activity
J4Q30_RS05810	COG2890	protein-(glutamine-N5) methyltransferase activity
J4Q30_RS05820	COG1435	thymidine kinase activity
J4Q30_RS05825	COG1942	4-Oxalocrotonate Tautomerase
J4Q30_RS05840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4Q30_RS05850	COG4708	membrane
J4Q30_RS05860	COG1970	mechanosensitive ion channel activity
J4Q30_RS05875	COG4509	Sortase family
J4Q30_RS05885	COG0681	Belongs to the peptidase S26 family
J4Q30_RS05925	COG0803	Belongs to the bacterial solute-binding protein 9 family
J4Q30_RS05925	COG3443	Belongs to the bacterial solute-binding protein 9 family
J4Q30_RS05930	COG0531	amino acid
J4Q30_RS05935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4Q30_RS05940	COG0785	Cytochrome C biogenesis protein
J4Q30_RS05965	COG0584	glycerophosphoryl diester phosphodiesterase
J4Q30_RS05970	COG2176	DNA-directed DNA polymerase activity
J4Q30_RS05980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J4Q30_RS05990	COG0494	nUDIX hydrolase
J4Q30_RS06010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4Q30_RS06035	COG4122	O-methyltransferase activity
J4Q30_RS06050	COG0500	methyltransferase
J4Q30_RS06050	COG3615	Tellurite resistance protein tehB
J4Q30_RS06060	COG0557	exoribonuclease II activity
J4Q30_RS06075	COG2814	Major facilitator Superfamily
J4Q30_RS06080	COG0237	dephospho-CoA kinase activity
J4Q30_RS06085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J4Q30_RS06095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4Q30_RS06105	COG1293	RNA-binding protein homologous to eukaryotic snRNP
J4Q30_RS06110	COG4193	domain, Protein
J4Q30_RS06110	COG5263	repeat protein
J4Q30_RS06115	COG0167	dihydroorotate dehydrogenase activity
J4Q30_RS06120	COG0543	2 iron, 2 sulfur cluster binding
J4Q30_RS06150	COG1131	(ABC) transporter
J4Q30_RS06160	COG0658	competence protein
J4Q30_RS06160	COG2333	competence protein COMEC
J4Q30_RS06165	COG1555	photosystem II stabilization
J4Q30_RS06165	COG1596	polysaccharide export
J4Q30_RS06170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4Q30_RS06190	COG1702	phosphate starvation-inducible protein PhoH
J4Q30_RS06200	COG2996	Protein conserved in bacteria
J4Q30_RS06210	COG0528	UMP kinase activity
J4Q30_RS06230	COG0470	DNA polymerase III
J4Q30_RS06240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4Q30_RS06255	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J4Q30_RS06260	COG0564	pseudouridine synthase activity
J4Q30_RS06265	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J4Q30_RS06270	COG0583	DNA-binding transcription factor activity
J4Q30_RS06290	COG0561	phosphatase activity
J4Q30_RS06295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4Q30_RS06315	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J4Q30_RS06330	COG1982	Orn Lys Arg decarboxylase major
J4Q30_RS06345	COG0577	efflux transmembrane transporter activity
J4Q30_RS06350	COG1136	(ABC) transporter
J4Q30_RS06370	COG2183	response to ionizing radiation
J4Q30_RS06375	COG0701	Predicted permease
J4Q30_RS06380	COG3689	TIGRFAM TIGR03943 family protein
J4Q30_RS06415	COG0469	pyruvate kinase activity
J4Q30_RS06435	COG1438	arginine binding
J4Q30_RS06445	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
J4Q30_RS06510	COG1104	cysteine desulfurase activity
J4Q30_RS06520	COG0697	spore germination
J4Q30_RS06520	COG1674	ftsk spoiiie
J4Q30_RS06525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4Q30_RS06525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4Q30_RS06525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4Q30_RS06530	COG1105	Belongs to the carbohydrate kinase PfkB family
J4Q30_RS06535	COG1349	DNA-binding transcription factor activity
J4Q30_RS06550	COG0628	permease
J4Q30_RS06555	COG1686	Belongs to the peptidase S11 family
J4Q30_RS06560	COG0719	Fe-S assembly protein
J4Q30_RS06570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4Q30_RS06575	COG0719	Fe-S assembly protein
J4Q30_RS06590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J4Q30_RS06595	COG1956	GAF domain-containing protein
J4Q30_RS06600	COG0539	negative regulation of cytoplasmic translation
J4Q30_RS06635	COG4166	transmembrane transport
J4Q30_RS06640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4Q30_RS06645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4Q30_RS06650	COG0187	DNA topoisomerase II activity
J4Q30_RS06665	COG1079	Belongs to the binding-protein-dependent transport system permease family
J4Q30_RS06670	COG4603	Belongs to the binding-protein-dependent transport system permease family
J4Q30_RS06675	COG3845	ABC transporter
J4Q30_RS06680	COG1744	ABC transporter substrate-binding protein PnrA-like
J4Q30_RS06685	COG0295	cytidine deaminase activity
J4Q30_RS06695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4Q30_RS06700	COG2813	Specifically methylates the guanine in position
J4Q30_RS06745	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J4Q30_RS06765	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4Q30_RS06770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J4Q30_RS06775	COG1126	abc transporter atp-binding protein
J4Q30_RS06780	COG0765	amino acid transport
J4Q30_RS06785	COG4703	Protein of unknown function (DUF1797)
J4Q30_RS06790	COG0542	response to heat
J4Q30_RS06800	COG0494	nUDIX hydrolase
J4Q30_RS06830	COG0187	DNA topoisomerase II activity
J4Q30_RS06840	COG0693	protein deglycase activity
J4Q30_RS06845	COG0772	Belongs to the SEDS family
J4Q30_RS06865	COG5002	protein histidine kinase activity
J4Q30_RS06870	COG0745	RESPONSE REGULATOR receiver
J4Q30_RS06895	COG1028	Short-chain dehydrogenase reductase Sdr
J4Q30_RS06905	COG4989	oxidoreductase activity
J4Q30_RS06925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4Q30_RS06925	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4Q30_RS06930	COG0577	efflux transmembrane transporter activity
J4Q30_RS06935	COG1136	(ABC) transporter
J4Q30_RS06940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4Q30_RS06945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4Q30_RS06950	COG1268	BioY protein
J4Q30_RS06960	COG4443	Transcriptional Coactivator p15 (PC4)
J4Q30_RS06970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4Q30_RS06970	COG1328	CTP reductase activity
J4Q30_RS07005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4Q30_RS07030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4Q30_RS07040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4Q30_RS07045	COG1126	abc transporter atp-binding protein
J4Q30_RS07055	COG0457	Tetratricopeptide repeat
J4Q30_RS07060	COG0628	permease
J4Q30_RS07065	COG2706	6-phosphogluconolactonase activity
J4Q30_RS07130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4Q30_RS07155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4Q30_RS07160	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J4Q30_RS07165	COG0626	cystathionine gamma-synthase activity
J4Q30_RS07170	COG1132	(ABC) transporter
J4Q30_RS07185	COG4166	transmembrane transport
J4Q30_RS07190	COG2244	polysaccharide biosynthetic process
J4Q30_RS07195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4Q30_RS07220	COG2827	Endonuclease containing a URI domain
J4Q30_RS07225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J4Q30_RS07230	COG1098	S1 RNA binding domain
J4Q30_RS07240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J4Q30_RS07245	COG0629	single-stranded DNA binding
J4Q30_RS07255	COG0017	Asparaginyl-tRNA synthetase
J4Q30_RS07265	COG0436	Aminotransferase
J4Q30_RS07285	COG3711	transcriptional antiterminator
J4Q30_RS07305	COG0242	peptide deformylase activity
J4Q30_RS07310	COG0625	glutathione transferase activity
J4Q30_RS07320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4Q30_RS07325	COG0488	(ABC) transporter
J4Q30_RS07330	COG0617	tRNA 3'-terminal CCA addition
J4Q30_RS07340	COG1307	EDD domain protein, DegV family
J4Q30_RS07360	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J4Q30_RS07370	COG5263	repeat protein
J4Q30_RS07370	COG5632	N-Acetylmuramoyl-L-alanine amidase
J4Q30_RS07540	COG0270	DNA (cytosine-5-)-methyltransferase activity
J4Q30_RS07545	COG0629	single-stranded DNA binding
J4Q30_RS07580	COG3561	AntA/AntB antirepressor
J4Q30_RS07590	COG1396	sequence-specific DNA binding
J4Q30_RS07605	COG0582	viral genome integration into host DNA
J4Q30_RS07610	COG1481	regulation of sporulation
J4Q30_RS07615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4Q30_RS07625	COG0251	oxidation-reduction process
J4Q30_RS07645	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4Q30_RS07655	COG5263	repeat protein
J4Q30_RS07655	COG4193	domain, Protein
J4Q30_RS07665	COG3935	DnaD domain protein
J4Q30_RS07680	COG2226	methyltransferase
J4Q30_RS07690	COG3842	ATPase activity
J4Q30_RS07700	COG1335	isochorismatase
J4Q30_RS07710	COG0513	Belongs to the DEAD box helicase family
J4Q30_RS07715	COG2223	nitrite transmembrane transporter activity
J4Q30_RS07720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4Q30_RS07725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4Q30_RS07730	COG3442	glutamine amidotransferase
J4Q30_RS07735	COG0006	proline dipeptidase activity
J4Q30_RS07750	COG4720	Psort location CytoplasmicMembrane, score
J4Q30_RS07755	COG0351	phosphomethylpyrimidine kinase
J4Q30_RS07775	COG2824	Alkylphosphonate utilization operon protein PhnA
J4Q30_RS07795	COG0463	Glycosyl transferase, family 2
J4Q30_RS07800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4Q30_RS07805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4Q30_RS07810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4Q30_RS07815	COG2384	SAM-dependent methyltransferase
J4Q30_RS07835	COG2801	Transposase and inactivated derivatives
J4Q30_RS07840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4Q30_RS07845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4Q30_RS07850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4Q30_RS07850	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4Q30_RS07850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4Q30_RS07855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4Q30_RS07875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4Q30_RS07880	COG0204	Acyl-transferase
J4Q30_RS07895	COG2910	NAD(P)H-binding
J4Q30_RS07920	COG5002	protein histidine kinase activity
J4Q30_RS07925	COG0745	RESPONSE REGULATOR receiver
J4Q30_RS07940	COG1959	2 iron, 2 sulfur cluster binding
J4Q30_RS08000	COG3590	peptidase
J4Q30_RS08015	COG0803	Belongs to the bacterial solute-binding protein 9 family
J4Q30_RS08020	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J4Q30_RS08030	COG0577	efflux transmembrane transporter activity
J4Q30_RS08030	COG1136	(ABC) transporter
J4Q30_RS08060	COG3599	regulation of cell shape
J4Q30_RS08080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4Q30_RS08100	COG1051	belongs to the nudix hydrolase family
J4Q30_RS08105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4Q30_RS08120	COG0768	penicillin binding
J4Q30_RS08135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4Q30_RS08155	COG2731	YhcH YjgK YiaL family protein
J4Q30_RS08160	COG0395	ABC-type sugar transport system, permease component
J4Q30_RS08165	COG1175	transmembrane transport
J4Q30_RS08175	COG1263	PTS System
J4Q30_RS08175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4Q30_RS08175	COG2190	(PTS) system
J4Q30_RS08185	COG0673	inositol 2-dehydrogenase activity
J4Q30_RS08190	COG4409	exo-alpha-(2->6)-sialidase activity
J4Q30_RS08200	COG1175	transmembrane transport
J4Q30_RS08205	COG1653	transport
J4Q30_RS08230	COG3458	cephalosporin-C deacetylase activity
J4Q30_RS08235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4Q30_RS08250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4Q30_RS08255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4Q30_RS08270	COG1131	(ABC) transporter
J4Q30_RS08300	COG0778	Nitroreductase
J4Q30_RS08305	COG1484	DNA-dependent DNA replication
J4Q30_RS08320	COG1725	Transcriptional regulator
J4Q30_RS08325	COG1131	(ABC) transporter
J4Q30_RS08335	COG1668	transmembrane transport
J4Q30_RS08340	COG4152	abc transporter atp-binding protein
J4Q30_RS08360	COG1940	carbohydrate kinase activity
J4Q30_RS08365	COG1263	PTS System
J4Q30_RS08365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4Q30_RS08365	COG2190	(PTS) system
J4Q30_RS08370	COG1621	beta-fructofuranosidase activity
J4Q30_RS08375	COG1609	Transcriptional regulator
J4Q30_RS08385	COG3425	synthase
J4Q30_RS08410	COG0515	serine threonine protein kinase
J4Q30_RS08410	COG2815	serine threonine protein kinase
J4Q30_RS08415	COG0631	protein serine/threonine phosphatase activity
J4Q30_RS08420	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4Q30_RS08420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4Q30_RS08430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4Q30_RS08440	COG0194	GDP metabolic process
J4Q30_RS08460	COG2226	methyltransferase
J4Q30_RS08465	COG0799	negative regulation of ribosome biogenesis
J4Q30_RS08475	COG1713	HD superfamily hydrolase involved in NAD metabolism
J4Q30_RS08480	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J4Q30_RS08485	COG1534	Rna-binding protein
J4Q30_RS08490	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4Q30_RS08505	COG0668	transmembrane transport
J4Q30_RS08530	COG3118	belongs to the thioredoxin family
J4Q30_RS08535	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4Q30_RS08545	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4Q30_RS08555	COG1164	Oligoendopeptidase f
J4Q30_RS08560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4Q30_RS08620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4Q30_RS08630	COG1621	beta-fructofuranosidase activity
J4Q30_RS08635	COG1653	transport
J4Q30_RS08640	COG0395	ABC-type sugar transport system, permease component
J4Q30_RS08645	COG4209	transmembrane transport
J4Q30_RS08655	COG3711	transcriptional antiterminator
J4Q30_RS08660	COG2261	transglycosylase associated protein
J4Q30_RS08680	COG3237	CsbD-like
J4Q30_RS08695	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J4Q30_RS08740	COG0512	Glutamine amidotransferase of anthranilate synthase
J4Q30_RS08745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4Q30_RS08765	COG1285	pathogenesis
J4Q30_RS08770	COG1178	ABC-type Fe3 transport system permease component
J4Q30_RS08790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4Q30_RS08795	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
J4Q30_RS08800	COG0704	Plays a role in the regulation of phosphate uptake
J4Q30_RS08810	COG5434	Belongs to the glycosyl hydrolase 28 family
J4Q30_RS08815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4Q30_RS08820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4Q30_RS08825	COG1132	(ABC) transporter
J4Q30_RS08830	COG1132	(ABC) transporter
J4Q30_RS08845	COG0708	Exodeoxyribonuclease III
J4Q30_RS08865	COG2233	PERMEase
J4Q30_RS08890	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J4Q30_RS08895	COG1609	Transcriptional regulator
J4Q30_RS08900	COG1063	alcohol dehydrogenase
J4Q30_RS08905	COG0789	Transcriptional regulator
J4Q30_RS08910	COG1230	cation diffusion facilitator family transporter
J4Q30_RS08920	COG3201	nicotinamide mononucleotide transporter
J4Q30_RS08925	COG1174	glycine betaine transport
J4Q30_RS08950	COG1363	Peptidase, m42
J4Q30_RS08965	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4Q30_RS08970	COG4605	iron ion homeostasis
J4Q30_RS08975	COG4604	ABC transporter, ATP-binding protein
J4Q30_RS08980	COG4607	ABC-type enterochelin transport system periplasmic component
J4Q30_RS08990	COG1187	pseudouridine synthase activity
J4Q30_RS09010	COG0517	IMP dehydrogenase activity
J4Q30_RS09020	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4Q30_RS09035	COG0366	Alpha amylase catalytic
J4Q30_RS09040	COG1263	PTS System
J4Q30_RS09040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4Q30_RS09045	COG2188	Transcriptional regulator
J4Q30_RS09065	COG4608	Belongs to the ABC transporter superfamily
J4Q30_RS09070	COG0444	Belongs to the ABC transporter superfamily
J4Q30_RS09075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4Q30_RS09080	COG0601	transmembrane transport
J4Q30_RS09085	COG4166	transmembrane transport
J4Q30_RS09095	COG0366	Alpha amylase catalytic
J4Q30_RS09105	COG0395	ABC-type sugar transport system, permease component
J4Q30_RS09110	COG1175	transmembrane transport
J4Q30_RS09115	COG1653	transport
J4Q30_RS09120	COG3345	alpha-galactosidase
J4Q30_RS09125	COG2207	Transcriptional regulator
J4Q30_RS09130	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J4Q30_RS09130	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J4Q30_RS09245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4Q30_RS09295	COG4221	oxidoreductase activity
J4Q30_RS09300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4Q30_RS09305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4Q30_RS09340	COG1132	(ABC) transporter
J4Q30_RS09395	COG3842	ATPase activity
J4Q30_RS09400	COG1178	ABC-type Fe3 transport system permease component
J4Q30_RS09405	COG1285	pathogenesis
J4Q30_RS09460	COG5263	repeat protein
J4Q30_RS09460	COG5632	N-Acetylmuramoyl-L-alanine amidase
J4Q30_RS09480	COG1316	TRANSCRIPTIONal
J4Q30_RS09490	COG0802	atpase or kinase
J4Q30_RS09515	COG1674	ftsk spoiiie
J4Q30_RS09525	COG2946	Replication initiation factor
J4Q30_RS09575	COG0741	lytic transglycosylase activity
J4Q30_RS09575	COG0791	NLP P60 protein
J4Q30_RS09615	COG0488	(ABC) transporter
J4Q30_RS09670	COG1136	(ABC) transporter
J4Q30_RS09670	COG0577	efflux transmembrane transporter activity
J4Q30_RS09695	COG1253	flavin adenine dinucleotide binding
J4Q30_RS09710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4Q30_RS09720	COG3480	Lon protease (S16) C-terminal proteolytic domain
J4Q30_RS09730	COG0742	ribosomal rna small subunit methyltransferase
J4Q30_RS09745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4Q30_RS09750	COG1254	Belongs to the acylphosphatase family
J4Q30_RS09760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4Q30_RS09770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4Q30_RS09785	COG1564	THIamine pyrophosphokinase
J4Q30_RS09795	COG1162	GTPase activity
J4Q30_RS09825	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J4Q30_RS09830	COG0084	hydrolase, TatD family'
J4Q30_RS09845	COG0436	Aminotransferase
J4Q30_RS09855	COG0589	response to stress
J4Q30_RS09860	COG0561	phosphatase activity
J4Q30_RS09865	COG0252	asparaginase activity
J4Q30_RS09875	COG1609	Transcriptional regulator
J4Q30_RS09880	COG2197	response regulator
J4Q30_RS09885	COG4585	Histidine kinase
J4Q30_RS09890	COG0842	Transport permease protein
J4Q30_RS09895	COG1131	(ABC) transporter
J4Q30_RS10000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J4Q30_RS10005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4Q30_RS10010	COG0564	pseudouridine synthase activity
J4Q30_RS10020	COG0577	efflux transmembrane transporter activity
J4Q30_RS10030	COG0157	Belongs to the NadC ModD family
J4Q30_RS10045	COG1129	ABC transporter
J4Q30_RS10050	COG2188	Transcriptional regulator
J4Q30_RS10055	COG2723	6-phospho-beta-galactosidase activity
J4Q30_RS10060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4Q30_RS10070	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4Q30_RS10075	COG1012	belongs to the aldehyde dehydrogenase family
J4Q30_RS10075	COG1454	alcohol dehydrogenase
J4Q30_RS10085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4Q30_RS10095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4Q30_RS10115	COG3623	hexulose-6-phosphate isomerase
J4Q30_RS10125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4Q30_RS10135	COG3037	sugar-specific permease SgaT UlaA
J4Q30_RS10145	COG1847	R3H domain protein
J4Q30_RS10150	COG0706	membrane insertase activity
J4Q30_RS10195	COG4537	Required for transformation and DNA binding
J4Q30_RS10205	COG5263	repeat protein
J4Q30_RS10205	COG5632	N-Acetylmuramoyl-L-alanine amidase
J4Q30_RS10400	COG0629	single-stranded DNA binding
J4Q30_RS10505	COG1459	type II secretion system
J4Q30_RS10510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4Q30_RS10520	COG1063	alcohol dehydrogenase
J4Q30_RS10545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J4Q30_RS10550	COG3759	membrane
J4Q30_RS10565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4Q30_RS10565	COG0131	Imidazoleglycerol-phosphate dehydratase
J4Q30_RS10570	COG0534	Mate efflux family protein
J4Q30_RS10685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J4Q30_RS10690	COG1132	(ABC) transporter
J4Q30_RS10700	COG1132	(ABC) transporter
J4Q30_RS10710	COG1438	arginine binding
J4Q30_RS10730	COG0745	RESPONSE REGULATOR receiver
J4Q30_RS10735	COG5002	protein histidine kinase activity
J4Q30_RS10740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4Q30_RS10745	COG0573	inorganic phosphate transmembrane transporter activity
J4Q30_RS10755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4Q30_RS10760	COG0704	Plays a role in the regulation of phosphate uptake
J4Q30_RS10785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J4Q30_RS10795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4Q30_RS10810	COG0697	spore germination
J4Q30_RS10815	COG4499	WXG100 protein secretion system (Wss), protein YukC
J4Q30_RS10815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4Q30_RS10825	COG2217	Heavy metal translocating P-type atpase
J4Q30_RS10835	COG2226	methyltransferase
J4Q30_RS10845	COG0058	SHG alpha-glucan phosphorylase activity
J4Q30_RS10850	COG1640	4-alpha-glucanotransferase
J4Q30_RS10855	COG2182	Extracellular solute-binding protein
J4Q30_RS10860	COG1175	transmembrane transport
J4Q30_RS10865	COG3833	ABC-type maltose transport systems, permease component
J4Q30_RS10870	COG5521	maltodextrose utilization protein MalA
J4Q30_RS10875	COG1609	Transcriptional regulator
J4Q30_RS10880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4Q30_RS10915	COG1476	TRANSCRIPTIONal
J4Q30_RS10940	COG1396	sequence-specific DNA binding
J4Q30_RS10945	COG2151	metal-sulfur cluster biosynthetic enzyme
J4Q30_RS10960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J4Q30_RS10965	COG3959	Transketolase, thiamine diphosphate binding domain
J4Q30_RS10980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4Q30_RS11000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J4Q30_RS11035	COG0383	alpha-mannosidase activity
J4Q30_RS11045	COG3537	Alpha-1,2-mannosidase
J4Q30_RS11065	COG0549	Belongs to the carbamate kinase family
J4Q30_RS11070	COG1288	antiporter activity
J4Q30_RS11075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4Q30_RS11085	COG3064	Membrane
J4Q30_RS11085	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J4Q30_RS11085	COG3583	domain protein
J4Q30_RS11100	COG1454	alcohol dehydrogenase
J4Q30_RS11120	COG3716	PTS system mannose fructose sorbose family IID component
J4Q30_RS11130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4Q30_RS11150	COG1070	Carbohydrate kinase
J4Q30_RS11160	COG0803	Belongs to the bacterial solute-binding protein 9 family
J4Q30_RS11160	COG3443	Belongs to the bacterial solute-binding protein 9 family
J4Q30_RS11165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4Q30_RS11170	COG1121	(ABC) transporter
J4Q30_RS11175	COG1846	Transcriptional regulator
J4Q30_RS11180	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
J4Q30_RS11190	COG1696	Membrane protein involved in D-alanine export
J4Q30_RS11205	COG2211	Major facilitator Superfamily
J4Q30_RS11225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4Q30_RS11230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4Q30_RS11250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4Q30_RS11270	COG1755	Isoprenylcysteine carboxyl methyltransferase
J4Q30_RS11275	COG5002	protein histidine kinase activity
J4Q30_RS11280	COG0745	RESPONSE REGULATOR receiver
J4Q30_RS11285	COG0542	response to heat
J4Q30_RS11290	COG4463	regulation of RNA biosynthetic process
J4Q30_RS11295	COG1116	anion transmembrane transporter activity
J4Q30_RS11300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4Q30_RS11305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4Q30_RS11325	COG0305	Participates in initiation and elongation during chromosome replication
J4Q30_RS11345	COG1040	competence protein
J4Q30_RS11350	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
J4Q30_RS11355	COG1739	Uncharacterized protein family UPF0029
J4Q30_RS11390	COG3942	CHAP domain
J4Q30_RS11400	COG1792	Involved in formation and maintenance of cell shape
J4Q30_RS11405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J4Q30_RS11410	COG1122	ATPase activity
J4Q30_RS11415	COG1122	ATPase activity
J4Q30_RS11420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4Q30_RS11430	COG0612	Peptidase, M16
J4Q30_RS11435	COG0612	Peptidase, M16
J4Q30_RS11440	COG2501	S4 domain
J4Q30_RS11450	COG0516	GMP reductase activity
J4Q30_RS11450	COG0517	IMP dehydrogenase activity
J4Q30_RS11455	COG0180	Tryptophanyl-tRNA synthetase
J4Q30_RS11460	COG0488	(ABC) transporter
J4Q30_RS11470	COG1511	domain protein
J4Q30_RS11475	COG1511	domain protein
J4Q30_RS11520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4Q30_RS11525	COG1475	DNA binding