locus-tag	class	description
GLO74_RS00005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GLO74_RS00050	COG1511	domain protein
GLO74_RS00060	COG1511	domain protein
GLO74_RS00070	COG0488	(ABC) transporter
GLO74_RS00075	COG0180	Tryptophanyl-tRNA synthetase
GLO74_RS00080	COG0516	GMP reductase activity
GLO74_RS00080	COG0517	IMP dehydrogenase activity
GLO74_RS00090	COG2501	S4 domain
GLO74_RS00095	COG0612	Peptidase, M16
GLO74_RS00100	COG0612	Peptidase, M16
GLO74_RS00110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GLO74_RS00115	COG1122	ATPase activity
GLO74_RS00120	COG1122	ATPase activity
GLO74_RS00125	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GLO74_RS00130	COG1792	Involved in formation and maintenance of cell shape
GLO74_RS00140	COG3942	CHAP domain
GLO74_RS00175	COG1739	Uncharacterized protein family UPF0029
GLO74_RS00180	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GLO74_RS00185	COG1040	competence protein
GLO74_RS00205	COG0305	Participates in initiation and elongation during chromosome replication
GLO74_RS00225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GLO74_RS00230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GLO74_RS00235	COG1116	anion transmembrane transporter activity
GLO74_RS00240	COG4463	regulation of RNA biosynthetic process
GLO74_RS00245	COG0542	response to heat
GLO74_RS00250	COG0745	RESPONSE REGULATOR receiver
GLO74_RS00255	COG5002	protein histidine kinase activity
GLO74_RS00260	COG1755	Isoprenylcysteine carboxyl methyltransferase
GLO74_RS00270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GLO74_RS00290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GLO74_RS00295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GLO74_RS00315	COG2211	Major facilitator Superfamily
GLO74_RS00330	COG1696	Membrane protein involved in D-alanine export
GLO74_RS00340	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GLO74_RS00345	COG1846	Transcriptional regulator
GLO74_RS00350	COG1121	(ABC) transporter
GLO74_RS00355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GLO74_RS00360	COG0803	Belongs to the bacterial solute-binding protein 9 family
GLO74_RS00360	COG3443	Belongs to the bacterial solute-binding protein 9 family
GLO74_RS00370	COG1070	Carbohydrate kinase
GLO74_RS00390	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLO74_RS00400	COG3716	PTS system mannose fructose sorbose family IID component
GLO74_RS00420	COG1454	alcohol dehydrogenase
GLO74_RS00440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GLO74_RS00445	COG1288	antiporter activity
GLO74_RS00450	COG0549	Belongs to the carbamate kinase family
GLO74_RS00470	COG3537	Alpha-1,2-mannosidase
GLO74_RS00480	COG0383	alpha-mannosidase activity
GLO74_RS00515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GLO74_RS00535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GLO74_RS00550	COG3959	Transketolase, thiamine diphosphate binding domain
GLO74_RS00555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GLO74_RS00570	COG2151	metal-sulfur cluster biosynthetic enzyme
GLO74_RS00600	COG1476	TRANSCRIPTIONal
GLO74_RS00635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GLO74_RS00645	COG1609	Transcriptional regulator
GLO74_RS00650	COG5521	maltodextrose utilization protein MalA
GLO74_RS00655	COG3833	ABC-type maltose transport systems, permease component
GLO74_RS00660	COG1175	transmembrane transport
GLO74_RS00665	COG2182	Extracellular solute-binding protein
GLO74_RS00670	COG1640	4-alpha-glucanotransferase
GLO74_RS00675	COG0058	SHG alpha-glucan phosphorylase activity
GLO74_RS00685	COG2226	methyltransferase
GLO74_RS00695	COG2217	Heavy metal translocating P-type atpase
GLO74_RS00705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GLO74_RS00705	COG4499	WXG100 protein secretion system (Wss), protein YukC
GLO74_RS00710	COG0697	spore germination
GLO74_RS00725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GLO74_RS00735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GLO74_RS00755	COG0704	Plays a role in the regulation of phosphate uptake
GLO74_RS00760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GLO74_RS00770	COG0573	inorganic phosphate transmembrane transporter activity
GLO74_RS00775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GLO74_RS00780	COG5002	protein histidine kinase activity
GLO74_RS00785	COG0745	RESPONSE REGULATOR receiver
GLO74_RS00810	COG1438	arginine binding
GLO74_RS00820	COG1132	(ABC) transporter
GLO74_RS00830	COG1132	(ABC) transporter
GLO74_RS00835	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GLO74_RS00950	COG0534	Mate efflux family protein
GLO74_RS00955	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GLO74_RS00955	COG0131	Imidazoleglycerol-phosphate dehydratase
GLO74_RS00970	COG3759	membrane
GLO74_RS00975	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GLO74_RS01000	COG1063	alcohol dehydrogenase
GLO74_RS01010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GLO74_RS01015	COG1459	type II secretion system
GLO74_RS01020	COG4537	Required for transformation and DNA binding
GLO74_RS01045	COG2226	methyltransferase
GLO74_RS01065	COG0706	membrane insertase activity
GLO74_RS01070	COG1847	R3H domain protein
GLO74_RS01080	COG3037	sugar-specific permease SgaT UlaA
GLO74_RS01090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GLO74_RS01100	COG3623	hexulose-6-phosphate isomerase
GLO74_RS01120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GLO74_RS01130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GLO74_RS01140	COG1454	alcohol dehydrogenase
GLO74_RS01140	COG1012	belongs to the aldehyde dehydrogenase family
GLO74_RS01145	COG1447	Phosphotransferase system cellobiose-specific component IIA
GLO74_RS01155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GLO74_RS01160	COG2723	6-phospho-beta-galactosidase activity
GLO74_RS01165	COG2188	Transcriptional regulator
GLO74_RS01170	COG1129	ABC transporter
GLO74_RS01180	COG0157	Belongs to the NadC ModD family
GLO74_RS01190	COG0577	efflux transmembrane transporter activity
GLO74_RS01200	COG0564	pseudouridine synthase activity
GLO74_RS01205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GLO74_RS01210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GLO74_RS01310	COG1131	(ABC) transporter
GLO74_RS01315	COG0842	Transport permease protein
GLO74_RS01320	COG4585	Histidine kinase
GLO74_RS01325	COG2197	response regulator
GLO74_RS01330	COG1609	Transcriptional regulator
GLO74_RS01335	COG0252	asparaginase activity
GLO74_RS01340	COG0561	phosphatase activity
GLO74_RS01345	COG0589	response to stress
GLO74_RS01355	COG0436	Aminotransferase
GLO74_RS01370	COG0084	hydrolase, TatD family'
GLO74_RS01375	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GLO74_RS01410	COG1162	GTPase activity
GLO74_RS01420	COG1564	THIamine pyrophosphokinase
GLO74_RS01435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GLO74_RS01445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GLO74_RS01455	COG1254	Belongs to the acylphosphatase family
GLO74_RS01460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GLO74_RS01475	COG0742	ribosomal rna small subunit methyltransferase
GLO74_RS01485	COG3480	Lon protease (S16) C-terminal proteolytic domain
GLO74_RS01495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GLO74_RS01510	COG1253	flavin adenine dinucleotide binding
GLO74_RS01535	COG1136	(ABC) transporter
GLO74_RS01535	COG0577	efflux transmembrane transporter activity
GLO74_RS01560	COG0802	atpase or kinase
GLO74_RS01570	COG1316	TRANSCRIPTIONal
GLO74_RS01590	COG5263	repeat protein
GLO74_RS01590	COG5632	N-Acetylmuramoyl-L-alanine amidase
GLO74_RS01675	COG1132	(ABC) transporter
GLO74_RS01680	COG2274	protein secretion by the type I secretion system
GLO74_RS01720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GLO74_RS01725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GLO74_RS01730	COG4221	oxidoreductase activity
GLO74_RS01770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GLO74_RS01890	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GLO74_RS01890	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GLO74_RS01895	COG2207	Transcriptional regulator
GLO74_RS01900	COG3345	alpha-galactosidase
GLO74_RS01905	COG1653	transport
GLO74_RS01910	COG1175	transmembrane transport
GLO74_RS01915	COG0395	ABC-type sugar transport system, permease component
GLO74_RS01925	COG0366	Alpha amylase catalytic
GLO74_RS01940	COG4166	transmembrane transport
GLO74_RS01945	COG0601	transmembrane transport
GLO74_RS01950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLO74_RS01955	COG0444	Belongs to the ABC transporter superfamily
GLO74_RS01960	COG4608	Belongs to the ABC transporter superfamily
GLO74_RS01970	COG4120	Belongs to the binding-protein-dependent transport system permease family
GLO74_RS01975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GLO74_RS01980	COG2188	Transcriptional regulator
GLO74_RS01985	COG1263	PTS System
GLO74_RS01985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLO74_RS01990	COG0366	Alpha amylase catalytic
GLO74_RS02005	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GLO74_RS02015	COG0517	IMP dehydrogenase activity
GLO74_RS02035	COG1187	pseudouridine synthase activity
GLO74_RS02045	COG4607	ABC-type enterochelin transport system periplasmic component
GLO74_RS02050	COG4604	ABC transporter, ATP-binding protein
GLO74_RS02055	COG4605	iron ion homeostasis
GLO74_RS02060	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLO74_RS02070	COG1363	Peptidase, m42
GLO74_RS02090	COG1125	glycine betaine transport
GLO74_RS02090	COG0517	IMP dehydrogenase activity
GLO74_RS02095	COG1174	glycine betaine transport
GLO74_RS02100	COG3201	nicotinamide mononucleotide transporter
GLO74_RS02110	COG1230	cation diffusion facilitator family transporter
GLO74_RS02115	COG0789	Transcriptional regulator
GLO74_RS02120	COG1063	alcohol dehydrogenase
GLO74_RS02125	COG1609	Transcriptional regulator
GLO74_RS02130	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GLO74_RS02155	COG2233	PERMEase
GLO74_RS02175	COG0708	Exodeoxyribonuclease III
GLO74_RS02190	COG1132	(ABC) transporter
GLO74_RS02195	COG1132	(ABC) transporter
GLO74_RS02200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GLO74_RS02205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GLO74_RS02210	COG5434	Belongs to the glycosyl hydrolase 28 family
GLO74_RS02235	COG1178	ABC-type Fe3 transport system permease component
GLO74_RS02240	COG1285	pathogenesis
GLO74_RS02265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GLO74_RS02270	COG0512	Glutamine amidotransferase of anthranilate synthase
GLO74_RS02285	COG0135	phosphoribosylanthranilate isomerase activity
GLO74_RS02325	COG1846	Transcriptional regulator
GLO74_RS02325	COG1940	carbohydrate kinase activity
GLO74_RS02330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GLO74_RS02340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GLO74_RS02345	COG1447	Phosphotransferase system cellobiose-specific component IIA
GLO74_RS02350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GLO74_RS02360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GLO74_RS02380	COG3237	CsbD-like
GLO74_RS02400	COG2261	transglycosylase associated protein
GLO74_RS02405	COG3711	transcriptional antiterminator
GLO74_RS02415	COG4209	transmembrane transport
GLO74_RS02420	COG0395	ABC-type sugar transport system, permease component
GLO74_RS02425	COG1653	transport
GLO74_RS02430	COG1621	beta-fructofuranosidase activity
GLO74_RS02440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GLO74_RS02475	COG1051	belongs to the nudix hydrolase family
GLO74_RS02490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GLO74_RS02495	COG1164	Oligoendopeptidase f
GLO74_RS02500	COG0640	Transcriptional regulator
GLO74_RS02505	COG1131	(ABC) transporter
GLO74_RS02520	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GLO74_RS02530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GLO74_RS02535	COG3118	belongs to the thioredoxin family
GLO74_RS02560	COG0668	transmembrane transport
GLO74_RS02575	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GLO74_RS02580	COG1534	Rna-binding protein
GLO74_RS02585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GLO74_RS02590	COG1713	HD superfamily hydrolase involved in NAD metabolism
GLO74_RS02600	COG0799	negative regulation of ribosome biogenesis
GLO74_RS02605	COG2226	methyltransferase
GLO74_RS02625	COG0194	GDP metabolic process
GLO74_RS02635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GLO74_RS02645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GLO74_RS02645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GLO74_RS02650	COG0631	protein serine/threonine phosphatase activity
GLO74_RS02655	COG2815	serine threonine protein kinase
GLO74_RS02655	COG0515	serine threonine protein kinase
GLO74_RS02680	COG3425	synthase
GLO74_RS02690	COG1609	Transcriptional regulator
GLO74_RS02695	COG1621	beta-fructofuranosidase activity
GLO74_RS02700	COG1263	PTS System
GLO74_RS02700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLO74_RS02700	COG2190	(PTS) system
GLO74_RS02705	COG1940	carbohydrate kinase activity
GLO74_RS02725	COG4152	abc transporter atp-binding protein
GLO74_RS02730	COG1668	transmembrane transport
GLO74_RS02740	COG1131	(ABC) transporter
GLO74_RS02745	COG1725	Transcriptional regulator
GLO74_RS02760	COG1484	DNA-dependent DNA replication
GLO74_RS02765	COG0778	Nitroreductase
GLO74_RS02805	COG1131	(ABC) transporter
GLO74_RS02815	COG0653	protein targeting
GLO74_RS02820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GLO74_RS02825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GLO74_RS02840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GLO74_RS02845	COG3458	cephalosporin-C deacetylase activity
GLO74_RS02865	COG1653	transport
GLO74_RS02870	COG1175	transmembrane transport
GLO74_RS02880	COG4409	exo-alpha-(2->6)-sialidase activity
GLO74_RS02895	COG1263	PTS System
GLO74_RS02895	COG2190	(PTS) system
GLO74_RS02895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLO74_RS02905	COG1175	transmembrane transport
GLO74_RS02910	COG0395	ABC-type sugar transport system, permease component
GLO74_RS02915	COG2731	YhcH YjgK YiaL family protein
GLO74_RS02930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GLO74_RS02945	COG0768	penicillin binding
GLO74_RS02960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GLO74_RS02965	COG1051	belongs to the nudix hydrolase family
GLO74_RS02985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GLO74_RS03005	COG3599	regulation of cell shape
GLO74_RS03035	COG1136	(ABC) transporter
GLO74_RS03035	COG0577	efflux transmembrane transporter activity
GLO74_RS03045	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GLO74_RS03050	COG0803	Belongs to the bacterial solute-binding protein 9 family
GLO74_RS03065	COG3590	peptidase
GLO74_RS03110	COG1959	2 iron, 2 sulfur cluster binding
GLO74_RS03125	COG0745	RESPONSE REGULATOR receiver
GLO74_RS03130	COG5002	protein histidine kinase activity
GLO74_RS03150	COG2910	NAD(P)H-binding
GLO74_RS03165	COG0204	Acyl-transferase
GLO74_RS03170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GLO74_RS03175	COG2384	SAM-dependent methyltransferase
GLO74_RS03180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GLO74_RS03185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GLO74_RS03195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GLO74_RS03200	COG0463	Glycosyl transferase, family 2
GLO74_RS03220	COG2824	Alkylphosphonate utilization operon protein PhnA
GLO74_RS03240	COG0351	phosphomethylpyrimidine kinase
GLO74_RS03245	COG4720	Psort location CytoplasmicMembrane, score
GLO74_RS03260	COG0006	proline dipeptidase activity
GLO74_RS03265	COG3442	glutamine amidotransferase
GLO74_RS03270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GLO74_RS03275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GLO74_RS03280	COG2223	nitrite transmembrane transporter activity
GLO74_RS03285	COG0513	Belongs to the DEAD box helicase family
GLO74_RS03295	COG1335	isochorismatase
GLO74_RS03305	COG3842	ATPase activity
GLO74_RS03315	COG2226	methyltransferase
GLO74_RS03330	COG3935	DnaD domain protein
GLO74_RS03340	COG4193	domain, Protein
GLO74_RS03340	COG5263	repeat protein
GLO74_RS03350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GLO74_RS03370	COG0251	oxidation-reduction process
GLO74_RS03380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GLO74_RS03385	COG1481	regulation of sporulation
GLO74_RS03395	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GLO74_RS03415	COG1307	EDD domain protein, DegV family
GLO74_RS03425	COG0617	tRNA 3'-terminal CCA addition
GLO74_RS03430	COG0488	(ABC) transporter
GLO74_RS03435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GLO74_RS03445	COG0625	glutathione transferase activity
GLO74_RS03450	COG0242	peptide deformylase activity
GLO74_RS03480	COG0436	Aminotransferase
GLO74_RS03490	COG0017	Asparaginyl-tRNA synthetase
GLO74_RS03500	COG0629	single-stranded DNA binding
GLO74_RS03505	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GLO74_RS03515	COG1098	S1 RNA binding domain
GLO74_RS03520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GLO74_RS03525	COG2827	Endonuclease containing a URI domain
GLO74_RS03545	COG3237	CsbD-like
GLO74_RS03550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GLO74_RS03555	COG2244	polysaccharide biosynthetic process
GLO74_RS03560	COG4166	transmembrane transport
GLO74_RS03565	COG1132	(ABC) transporter
GLO74_RS03570	COG1132	(ABC) transporter
GLO74_RS03575	COG0626	cystathionine gamma-synthase activity
GLO74_RS03580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GLO74_RS03585	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GLO74_RS03610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GLO74_RS03675	COG2706	6-phosphogluconolactonase activity
GLO74_RS03680	COG0628	permease
GLO74_RS03695	COG1126	abc transporter atp-binding protein
GLO74_RS03700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLO74_RS03710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GLO74_RS03745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GLO74_RS03760	COG0513	Belongs to the DEAD box helicase family
GLO74_RS03775	COG0726	polysaccharide deacetylase
GLO74_RS03785	COG0656	L-ascorbic acid biosynthetic process
GLO74_RS03810	COG0431	NADPH-dependent FMN reductase
GLO74_RS03810	COG3976	FMN-binding domain protein
GLO74_RS03810	COG1053	succinate dehydrogenase
GLO74_RS03840	COG1272	protein, Hemolysin III
GLO74_RS03860	COG1393	Belongs to the ArsC family
GLO74_RS03870	COG1126	abc transporter atp-binding protein
GLO74_RS03880	COG0492	ferredoxin-NADP+ reductase activity
GLO74_RS03905	COG0561	phosphatase activity
GLO74_RS03920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GLO74_RS03925	COG0697	spore germination
GLO74_RS03930	COG2188	Transcriptional regulator
GLO74_RS03970	COG1129	ABC transporter
GLO74_RS03985	COG1132	(ABC) transporter
GLO74_RS04015	COG0826	peptidase U32
GLO74_RS04050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GLO74_RS04060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GLO74_RS04110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GLO74_RS04120	COG0647	UMP catabolic process
GLO74_RS04130	COG1393	Belongs to the ArsC family
GLO74_RS04140	COG0483	inositol monophosphate 1-phosphatase activity
GLO74_RS04145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GLO74_RS04145	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GLO74_RS04150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GLO74_RS04155	COG0573	inorganic phosphate transmembrane transporter activity
GLO74_RS04160	COG0581	inorganic phosphate transmembrane transporter activity
GLO74_RS04165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GLO74_RS04170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GLO74_RS04175	COG0704	Plays a role in the regulation of phosphate uptake
GLO74_RS04180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLO74_RS04185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GLO74_RS04190	COG3527	Alpha-acetolactate decarboxylase
GLO74_RS04205	COG3842	ATPase activity
GLO74_RS04245	COG4555	ABC transporter
GLO74_RS04255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GLO74_RS04280	COG0287	Prephenate dehydrogenase
GLO74_RS04290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GLO74_RS04295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GLO74_RS04300	COG0077	Prephenate dehydratase
GLO74_RS04310	COG3475	LICD family
GLO74_RS04320	COG1215	transferase activity, transferring glycosyl groups
GLO74_RS04355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GLO74_RS04355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GLO74_RS04360	COG1132	(ABC) transporter
GLO74_RS04370	COG0402	S-adenosylhomocysteine deaminase activity
GLO74_RS04420	COG0515	serine threonine protein kinase
GLO74_RS04430	COG1136	(ABC) transporter
GLO74_RS04430	COG0577	efflux transmembrane transporter activity
GLO74_RS04455	COG1737	Transcriptional regulator
GLO74_RS04460	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GLO74_RS04465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GLO74_RS04470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLO74_RS04480	COG4409	exo-alpha-(2->6)-sialidase activity
GLO74_RS04485	COG0673	inositol 2-dehydrogenase activity
GLO74_RS04500	COG1269	ATP hydrolysis coupled proton transport
GLO74_RS04505	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GLO74_RS04585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GLO74_RS04615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GLO74_RS04620	COG0716	FMN binding
GLO74_RS04625	COG0077	Prephenate dehydratase
GLO74_RS04625	COG1605	Chorismate mutase
GLO74_RS04630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GLO74_RS04635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GLO74_RS04655	COG1078	dGTPase activity
GLO74_RS04670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GLO74_RS04685	COG1704	LemA family
GLO74_RS04695	COG0488	(ABC) transporter
GLO74_RS04710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GLO74_RS04725	COG0505	Belongs to the CarA family
GLO74_RS04735	COG3475	LICD family
GLO74_RS04740	COG3475	LICD family
GLO74_RS04750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GLO74_RS04755	COG1063	alcohol dehydrogenase
GLO74_RS04770	COG4750	Nucleotidyl transferase
GLO74_RS04775	COG0758	DNA mediated transformation
GLO74_RS04785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GLO74_RS04790	COG2832	Protein of unknown function (DUF454)
GLO74_RS04795	COG3142	Participates in the control of copper homeostasis
GLO74_RS04815	COG0473	3-isopropylmalate dehydrogenase activity
GLO74_RS04825	COG0066	3-isopropylmalate dehydratase activity
GLO74_RS04835	COG1401	restriction endodeoxyribonuclease activity
GLO74_RS04860	COG1196	nuclear chromosome segregation
GLO74_RS04865	COG0561	phosphatase activity
GLO74_RS04870	COG0561	phosphatase activity
GLO74_RS04875	COG0552	protein localization to endoplasmic reticulum
GLO74_RS04880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GLO74_RS04885	COG1126	abc transporter atp-binding protein
GLO74_RS04890	COG0765	amino acid transport
GLO74_RS04915	COG2816	NAD+ diphosphatase activity
GLO74_RS04920	COG1827	regulation of RNA biosynthetic process
GLO74_RS04930	COG4684	Psort location CytoplasmicMembrane, score
GLO74_RS04935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GLO74_RS04950	COG1194	a g-specific adenine glycosylase
GLO74_RS04955	COG0745	RESPONSE REGULATOR receiver
GLO74_RS04960	COG5002	protein histidine kinase activity
GLO74_RS04965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GLO74_RS04995	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GLO74_RS05000	COG3764	Sortase (surface protein transpeptidase)
GLO74_RS05020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GLO74_RS05050	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GLO74_RS05055	COG1438	arginine binding
GLO74_RS05060	COG0497	DNA recombination
GLO74_RS05065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GLO74_RS05120	COG3684	Belongs to the aldolase LacD family
GLO74_RS05125	COG3711	transcriptional antiterminator
GLO74_RS05155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GLO74_RS05160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GLO74_RS05165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GLO74_RS05170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GLO74_RS05190	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GLO74_RS05195	COG1011	Hydrolase
GLO74_RS05210	COG1051	belongs to the nudix hydrolase family
GLO74_RS05215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GLO74_RS05225	COG0534	Mate efflux family protein
GLO74_RS05230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GLO74_RS05235	COG0022	dehydrogenase e1 component
GLO74_RS05240	COG0508	dehydrogenase complex catalyzes the overall conversion of
GLO74_RS05245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GLO74_RS05250	COG0095	Lipoate-protein ligase
GLO74_RS05270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GLO74_RS05275	COG3064	Membrane
GLO74_RS05280	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GLO74_RS05280	COG3583	domain protein
GLO74_RS05290	COG1074	ATP-dependent DNA helicase activity
GLO74_RS05310	COG0582	viral genome integration into host DNA
GLO74_RS05330	COG0560	Phosphoserine phosphatase
GLO74_RS05335	COG0560	Phosphoserine phosphatase
GLO74_RS05345	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GLO74_RS05355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GLO74_RS05360	COG1012	belongs to the aldehyde dehydrogenase family
GLO74_RS05365	COG1523	belongs to the glycosyl hydrolase 13 family
GLO74_RS05375	COG2814	Major facilitator Superfamily
GLO74_RS05385	COG0488	(ABC) transporter
GLO74_RS05395	COG1307	EDD domain protein, DegV family
GLO74_RS05400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GLO74_RS05405	COG0196	riboflavin kinase activity
GLO74_RS05445	COG0280	phosphate acetyltransferase
GLO74_RS05450	COG0564	pseudouridine synthase activity
GLO74_RS05460	COG2357	RelA SpoT domain protein
GLO74_RS05470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GLO74_RS05475	COG1104	cysteine desulfurase activity
GLO74_RS05495	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GLO74_RS05505	COG0210	DNA helicase
GLO74_RS05515	COG0024	Methionine aminopeptidase
GLO74_RS05520	COG4109	DRTGG domain
GLO74_RS05530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GLO74_RS05555	COG0438	transferase activity, transferring glycosyl groups
GLO74_RS05560	COG0438	transferase activity, transferring glycosyl groups
GLO74_RS05565	COG2151	metal-sulfur cluster biosynthetic enzyme
GLO74_RS05570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLO74_RS05575	COG0358	DNA primase activity
GLO74_RS05580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GLO74_RS05595	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GLO74_RS05600	COG0772	Belongs to the SEDS family
GLO74_RS05625	COG1131	(ABC) transporter
GLO74_RS05655	COG3843	relaxase mobilization nuclease domain protein
GLO74_RS05680	COG0542	response to heat
GLO74_RS05685	COG1396	sequence-specific DNA binding
GLO74_RS05695	COG0366	Alpha amylase catalytic
GLO74_RS05700	COG1597	lipid kinase activity
GLO74_RS05725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GLO74_RS05775	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLO74_RS05780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLO74_RS05800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GLO74_RS05815	COG3843	relaxase mobilization nuclease domain protein
GLO74_RS05845	COG0542	response to heat
GLO74_RS05850	COG1396	sequence-specific DNA binding
GLO74_RS05935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GLO74_RS05945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GLO74_RS05950	COG1396	sequence-specific DNA binding
GLO74_RS06015	COG1674	ftsk spoiiie
GLO74_RS06025	COG2946	Replication initiation factor
GLO74_RS06070	COG0741	lytic transglycosylase activity
GLO74_RS06070	COG0791	NLP P60 protein
GLO74_RS06085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GLO74_RS06140	COG0270	DNA (cytosine-5-)-methyltransferase activity
GLO74_RS06155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GLO74_RS06165	COG0741	lytic transglycosylase activity
GLO74_RS06190	COG2890	protein-(glutamine-N5) methyltransferase activity
GLO74_RS06200	COG1435	thymidine kinase activity
GLO74_RS06205	COG1942	4-Oxalocrotonate Tautomerase
GLO74_RS06210	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GLO74_RS06220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GLO74_RS06230	COG4708	membrane
GLO74_RS06240	COG1970	mechanosensitive ion channel activity
GLO74_RS06290	COG3443	Belongs to the bacterial solute-binding protein 9 family
GLO74_RS06290	COG0803	Belongs to the bacterial solute-binding protein 9 family
GLO74_RS06295	COG0531	amino acid
GLO74_RS06300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GLO74_RS06305	COG0785	Cytochrome C biogenesis protein
GLO74_RS06325	COG0584	glycerophosphoryl diester phosphodiesterase
GLO74_RS06330	COG2176	DNA-directed DNA polymerase activity
GLO74_RS06340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GLO74_RS06350	COG0494	nUDIX hydrolase
GLO74_RS06355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GLO74_RS06370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GLO74_RS06395	COG4122	O-methyltransferase activity
GLO74_RS06410	COG0500	methyltransferase
GLO74_RS06410	COG3615	Tellurite resistance protein tehB
GLO74_RS06420	COG0557	exoribonuclease II activity
GLO74_RS06430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GLO74_RS06435	COG2814	Major facilitator Superfamily
GLO74_RS06440	COG0237	dephospho-CoA kinase activity
GLO74_RS06445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GLO74_RS06455	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GLO74_RS06465	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GLO74_RS06470	COG5263	repeat protein
GLO74_RS06470	COG4193	domain, Protein
GLO74_RS06475	COG0167	dihydroorotate dehydrogenase activity
GLO74_RS06480	COG0543	2 iron, 2 sulfur cluster binding
GLO74_RS06510	COG1131	(ABC) transporter
GLO74_RS06520	COG0658	competence protein
GLO74_RS06520	COG2333	competence protein COMEC
GLO74_RS06525	COG1596	polysaccharide export
GLO74_RS06525	COG1555	photosystem II stabilization
GLO74_RS06530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GLO74_RS06535	COG0686	Belongs to the AlaDH PNT family
GLO74_RS06540	COG0686	Belongs to the AlaDH PNT family
GLO74_RS06545	COG0686	Belongs to the AlaDH PNT family
GLO74_RS06565	COG1702	phosphate starvation-inducible protein PhoH
GLO74_RS06575	COG2996	Protein conserved in bacteria
GLO74_RS06585	COG0528	UMP kinase activity
GLO74_RS06625	COG0470	DNA polymerase III
GLO74_RS06635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GLO74_RS06650	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GLO74_RS06655	COG0564	pseudouridine synthase activity
GLO74_RS06660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GLO74_RS06665	COG0583	DNA-binding transcription factor activity
GLO74_RS06685	COG0561	phosphatase activity
GLO74_RS06690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GLO74_RS06710	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GLO74_RS06720	COG1982	Orn Lys Arg decarboxylase major
GLO74_RS06735	COG0577	efflux transmembrane transporter activity
GLO74_RS06740	COG1136	(ABC) transporter
GLO74_RS06760	COG2183	response to ionizing radiation
GLO74_RS06770	COG0701	Predicted permease
GLO74_RS06775	COG3689	TIGRFAM TIGR03943 family protein
GLO74_RS06805	COG0469	pyruvate kinase activity
GLO74_RS06825	COG1438	arginine binding
GLO74_RS06835	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GLO74_RS06885	COG1104	cysteine desulfurase activity
GLO74_RS06895	COG1674	ftsk spoiiie
GLO74_RS06895	COG0697	spore germination
GLO74_RS06900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GLO74_RS06900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GLO74_RS06900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GLO74_RS06905	COG1105	Belongs to the carbohydrate kinase PfkB family
GLO74_RS06910	COG1349	DNA-binding transcription factor activity
GLO74_RS06925	COG0628	permease
GLO74_RS06930	COG1686	Belongs to the peptidase S11 family
GLO74_RS06935	COG0719	Fe-S assembly protein
GLO74_RS06945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GLO74_RS06950	COG0719	Fe-S assembly protein
GLO74_RS06965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GLO74_RS06970	COG1956	GAF domain-containing protein
GLO74_RS06980	COG0539	negative regulation of cytoplasmic translation
GLO74_RS07015	COG4166	transmembrane transport
GLO74_RS07020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GLO74_RS07025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GLO74_RS07030	COG0187	DNA topoisomerase II activity
GLO74_RS07045	COG1079	Belongs to the binding-protein-dependent transport system permease family
GLO74_RS07050	COG4603	Belongs to the binding-protein-dependent transport system permease family
GLO74_RS07055	COG3845	ABC transporter
GLO74_RS07060	COG1744	ABC transporter substrate-binding protein PnrA-like
GLO74_RS07065	COG0295	cytidine deaminase activity
GLO74_RS07075	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GLO74_RS07080	COG2813	Specifically methylates the guanine in position
GLO74_RS07120	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GLO74_RS07140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GLO74_RS07150	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GLO74_RS07155	COG1126	abc transporter atp-binding protein
GLO74_RS07160	COG0765	amino acid transport
GLO74_RS07165	COG4703	Protein of unknown function (DUF1797)
GLO74_RS07170	COG0542	response to heat
GLO74_RS07180	COG0494	nUDIX hydrolase
GLO74_RS07200	COG0187	DNA topoisomerase II activity
GLO74_RS07210	COG0693	protein deglycase activity
GLO74_RS07215	COG0772	Belongs to the SEDS family
GLO74_RS07235	COG5002	protein histidine kinase activity
GLO74_RS07240	COG0745	RESPONSE REGULATOR receiver
GLO74_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
GLO74_RS07285	COG4989	oxidoreductase activity
GLO74_RS07310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GLO74_RS07310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GLO74_RS07315	COG0577	efflux transmembrane transporter activity
GLO74_RS07320	COG1136	(ABC) transporter
GLO74_RS07325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GLO74_RS07330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GLO74_RS07340	COG0577	efflux transmembrane transporter activity
GLO74_RS07340	COG1136	(ABC) transporter
GLO74_RS07355	COG1268	BioY protein
GLO74_RS07365	COG4443	Transcriptional Coactivator p15 (PC4)
GLO74_RS07375	COG1328	CTP reductase activity
GLO74_RS07375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GLO74_RS07400	COG1837	Belongs to the UPF0109 family
GLO74_RS07430	COG0488	(ABC) transporter
GLO74_RS07440	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GLO74_RS07445	COG4470	Protein conserved in bacteria
GLO74_RS07450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GLO74_RS07460	COG0167	dihydroorotate dehydrogenase activity
GLO74_RS07470	COG0513	Belongs to the DEAD box helicase family
GLO74_RS07480	COG2190	(PTS) system
GLO74_RS07480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLO74_RS07480	COG1263	PTS System
GLO74_RS07490	COG2177	Part of the ABC transporter FtsEX involved in
GLO74_RS07495	COG2884	Cell division ATP-binding protein ftsE
GLO74_RS07505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GLO74_RS07505	COG0617	tRNA 3'-terminal CCA addition
GLO74_RS07505	COG0517	IMP dehydrogenase activity
GLO74_RS07545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GLO74_RS07550	COG2131	deaminase
GLO74_RS07560	COG1307	EDD domain protein, DegV family
GLO74_RS07565	COG2081	HI0933 family
GLO74_RS07580	COG0733	neurotransmitter:sodium symporter activity
GLO74_RS07585	COG1482	cell wall glycoprotein biosynthetic process
GLO74_RS07590	COG2723	6-phospho-beta-galactosidase activity
GLO74_RS07605	COG0028	Belongs to the TPP enzyme family
GLO74_RS07610	COG2217	Heavy metal translocating P-type atpase
GLO74_RS07630	COG0352	thiamine-phosphate diphosphorylase activity
GLO74_RS07645	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GLO74_RS07655	COG4172	Belongs to the ABC transporter superfamily
GLO74_RS07665	COG0352	thiamine-phosphate diphosphorylase activity
GLO74_RS07670	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GLO74_RS07680	COG1304	FMN binding
GLO74_RS07690	COG1304	FMN binding
GLO74_RS07695	COG0765	amino acid transport
GLO74_RS07700	COG0765	amino acid transport
GLO74_RS07705	COG1126	abc transporter atp-binding protein
GLO74_RS07715	COG1131	(ABC) transporter
GLO74_RS07740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GLO74_RS07750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GLO74_RS07765	COG1136	(ABC) transporter
GLO74_RS07785	COG1217	gtp-binding protein TYPA
GLO74_RS07790	COG1187	pseudouridine synthase activity
GLO74_RS07800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GLO74_RS07815	COG0300	oxidoreductase activity
GLO74_RS07825	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GLO74_RS07850	COG1940	carbohydrate kinase activity
GLO74_RS07865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GLO74_RS07870	COG3064	Membrane
GLO74_RS07880	COG2972	Histidine kinase
GLO74_RS07885	COG2207	Transcriptional regulator
GLO74_RS07885	COG4753	response regulator
GLO74_RS07890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GLO74_RS07890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GLO74_RS07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GLO74_RS07900	COG0785	Cytochrome C biogenesis protein
GLO74_RS07920	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GLO74_RS07940	COG3250	beta-galactosidase activity
GLO74_RS07945	COG3775	system Galactitol-specific IIC component
GLO74_RS07965	COG1404	Belongs to the peptidase S8 family
GLO74_RS07995	COG4555	ABC transporter
GLO74_RS08030	COG1363	Peptidase, m42
GLO74_RS08035	COG1114	Component of the transport system for branched-chain amino acids
GLO74_RS08050	COG1573	uracil-dna glycosylase
GLO74_RS08065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLO74_RS08105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GLO74_RS08105	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GLO74_RS08115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLO74_RS08120	COG0765	amino acid transport
GLO74_RS08125	COG0765	amino acid transport
GLO74_RS08130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GLO74_RS08135	COG0191	fructose-bisphosphate aldolase activity
GLO74_RS08140	COG5002	protein histidine kinase activity
GLO74_RS08145	COG0745	RESPONSE REGULATOR receiver
GLO74_RS08150	COG0577	efflux transmembrane transporter activity
GLO74_RS08155	COG1136	(ABC) transporter
GLO74_RS08160	COG0577	efflux transmembrane transporter activity
GLO74_RS08180	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GLO74_RS08185	COG0215	cysteine-tRNA ligase activity
GLO74_RS08195	COG1045	serine acetyltransferase
GLO74_RS08210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GLO74_RS08215	COG3620	sequence-specific DNA binding
GLO74_RS08230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GLO74_RS08230	COG0072	phenylalanine-tRNA ligase activity
GLO74_RS08235	COG0456	acetyltransferase
GLO74_RS08250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLO74_RS08250	COG1263	PTS System
GLO74_RS08250	COG2190	(PTS) system
GLO74_RS08255	COG3711	transcriptional antiterminator
GLO74_RS08280	COG0525	valine-tRNA ligase activity
GLO74_RS08290	COG0519	Catalyzes the synthesis of GMP from XMP
GLO74_RS08355	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GLO74_RS08360	COG0195	Participates in both transcription termination and antitermination
GLO74_RS08380	COG1266	CAAX protease self-immunity
GLO74_RS08430	COG2274	protein secretion by the type I secretion system
GLO74_RS08435	COG2274	protein secretion by the type I secretion system
GLO74_RS08440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GLO74_RS08450	COG3290	protein histidine kinase activity
GLO74_RS08475	COG1131	(ABC) transporter
GLO74_RS08480	COG0537	adenosine 5'-monophosphoramidase activity
GLO74_RS08495	COG0484	heat shock protein binding
GLO74_RS08550	COG4974	Belongs to the 'phage' integrase family
GLO74_RS08565	COG0174	glutamine synthetase
GLO74_RS08570	COG0789	Transcriptional regulator
GLO74_RS08590	COG1283	sodium-dependent phosphate transmembrane transporter activity
GLO74_RS08595	COG0504	CTP synthase activity
GLO74_RS08605	COG1247	-acetyltransferase
GLO74_RS08615	COG0671	phosphoesterase, PA-phosphatase related
GLO74_RS08620	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GLO74_RS08635	COG1122	ATPase activity
GLO74_RS08655	COG0569	domain protein
GLO74_RS08660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GLO74_RS08690	COG1882	Formate acetyltransferase
GLO74_RS08695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GLO74_RS08715	COG0765	amino acid transport
GLO74_RS08730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GLO74_RS08750	COG0440	acetolactate synthase activity
GLO74_RS08755	COG0028	Belongs to the TPP enzyme family
GLO74_RS08760	COG1461	Dihydroxyacetone kinase
GLO74_RS08770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GLO74_RS08780	COG1442	glycosyl transferase family 8
GLO74_RS08785	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GLO74_RS08840	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GLO74_RS08845	COG0439	Biotin carboxylase
GLO74_RS08860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GLO74_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
GLO74_RS08870	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GLO74_RS08880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GLO74_RS08890	COG1846	Transcriptional regulator
GLO74_RS08895	COG1024	Enoyl-CoA hydratase
GLO74_RS08900	COG0527	aspartate kinase activity
GLO74_RS08910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GLO74_RS08925	COG1115	amino acid carrier protein
GLO74_RS08950	COG0681	Belongs to the peptidase S26 family
GLO74_RS08955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GLO74_RS08970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GLO74_RS08975	COG3711	transcriptional antiterminator
GLO74_RS08980	COG2213	PTS system mannitol-specific
GLO74_RS09020	COG2197	response regulator
GLO74_RS09025	COG4585	Histidine kinase
GLO74_RS09080	COG0745	RESPONSE REGULATOR receiver
GLO74_RS09085	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GLO74_RS09095	COG0116	Belongs to the methyltransferase superfamily
GLO74_RS09120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GLO74_RS09125	COG0366	Alpha amylase catalytic
GLO74_RS09130	COG4166	transmembrane transport
GLO74_RS09140	COG1091	dTDP-4-dehydrorhamnose reductase activity
GLO74_RS09145	COG1088	dTDP-glucose 4,6-dehydratase activity
GLO74_RS09155	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GLO74_RS09175	COG3475	LICD family
GLO74_RS09185	COG1215	transferase activity, transferring glycosyl groups
GLO74_RS09210	COG3475	LICD family
GLO74_RS09235	COG4464	protein tyrosine phosphatase activity
GLO74_RS09250	COG4166	transmembrane transport
GLO74_RS09255	COG0366	Alpha amylase catalytic
GLO74_RS09285	COG0768	penicillin binding
GLO74_RS09290	COG4839	cell division protein FtsL
GLO74_RS09315	COG1609	Transcriptional regulator
GLO74_RS09330	COG3716	PTS system mannose fructose sorbose family IID component
GLO74_RS09335	COG3715	PTS system
GLO74_RS09340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLO74_RS09345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GLO74_RS09355	COG1028	Short-chain dehydrogenase reductase Sdr
GLO74_RS09380	COG5492	domain, Protein
GLO74_RS09385	COG0386	Belongs to the glutathione peroxidase family
GLO74_RS09410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GLO74_RS09420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GLO74_RS09420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GLO74_RS09430	COG0285	dihydrofolate synthase activity
GLO74_RS09435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GLO74_RS09445	COG2252	PERMEase
GLO74_RS09450	COG0561	phosphatase activity
GLO74_RS09455	COG1064	alcohol dehydrogenase
GLO74_RS09465	COG3715	PTS system
GLO74_RS09470	COG3716	PTS system mannose fructose sorbose family IID component
GLO74_RS09475	COG3579	cysteine-type endopeptidase activity
GLO74_RS09480	COG1187	pseudouridine synthase activity
GLO74_RS09485	COG2261	transglycosylase associated protein
GLO74_RS09490	COG2309	aminopeptidase activity
GLO74_RS09510	COG2176	DNA-directed DNA polymerase activity
GLO74_RS09530	COG1523	belongs to the glycosyl hydrolase 13 family
GLO74_RS09540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GLO74_RS09545	COG2723	6-phospho-beta-galactosidase activity
GLO74_RS09555	COG0750	zinc metalloprotease
GLO74_RS09560	COG4589	Belongs to the CDS family
GLO74_RS09565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GLO74_RS09610	COG1882	Formate acetyltransferase
GLO74_RS09615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GLO74_RS09620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GLO74_RS09625	COG1447	Phosphotransferase system cellobiose-specific component IIA
GLO74_RS09635	COG1349	DNA-binding transcription factor activity
GLO74_RS09640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GLO74_RS09660	COG3842	ATPase activity
GLO74_RS09680	COG3830	Belongs to the UPF0237 family
GLO74_RS09690	COG0202	RNA polymerase activity
GLO74_RS09695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GLO74_RS09705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GLO74_RS09710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GLO74_RS09720	COG0201	protein transport
GLO74_RS09735	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GLO74_RS09775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GLO74_RS09800	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GLO74_RS09865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GLO74_RS09875	COG0285	dihydrofolate synthase activity
GLO74_RS09900	COG1393	Belongs to the ArsC family
GLO74_RS09905	COG0006	proline dipeptidase activity
GLO74_RS09910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GLO74_RS09935	COG2818	Glycosylase
GLO74_RS09955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GLO74_RS09955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GLO74_RS09985	COG1780	Probably involved in ribonucleotide reductase function
GLO74_RS09995	COG2207	Transcriptional regulator
GLO74_RS09995	COG4753	response regulator
GLO74_RS10000	COG2972	Histidine kinase
GLO74_RS10020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GLO74_RS10025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GLO74_RS10030	COG1464	Belongs to the NlpA lipoprotein family
GLO74_RS10035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GLO74_RS10075	COG1396	sequence-specific DNA binding
GLO74_RS10140	COG1214	PFAM Peptidase M22, glycoprotease
GLO74_RS10175	COG0445	tRNA wobble uridine modification
GLO74_RS10180	COG0494	nUDIX hydrolase
GLO74_RS10260	COG1760	l-serine dehydratase
GLO74_RS10265	COG1760	l-serine dehydratase
GLO74_RS10270	COG0546	phosphoglycolate phosphatase activity
GLO74_RS10295	COG1695	Transcriptional regulator
GLO74_RS10325	COG1653	transport
GLO74_RS10330	COG0395	ABC-type sugar transport system, permease component
GLO74_RS10335	COG4209	transmembrane transport
GLO74_RS10360	COG5002	protein histidine kinase activity
GLO74_RS10385	COG0569	domain protein
GLO74_RS10390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GLO74_RS10420	COG1937	Protein conserved in bacteria
GLO74_RS10425	COG2514	catechol 2,3-dioxygenase activity
GLO74_RS10435	COG2222	sugar isomerase
GLO74_RS10445	COG3716	PTS system mannose fructose sorbose family IID component
GLO74_RS10450	COG3715	PTS system
GLO74_RS10455	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GLO74_RS10470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GLO74_RS10470	COG3583	domain protein
GLO74_RS10470	COG3064	Membrane
GLO74_RS10475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GLO74_RS10490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GLO74_RS10495	COG0151	Belongs to the GarS family
GLO74_RS10510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GLO74_RS10525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GLO74_RS10535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GLO74_RS10540	COG2274	protein secretion by the type I secretion system
GLO74_RS10550	COG1134	teichoic acid transport
GLO74_RS10550	COG1388	LysM domain
GLO74_RS10585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GLO74_RS10600	COG0436	Aminotransferase
GLO74_RS10605	COG2855	membrane
GLO74_RS10615	COG1832	CoA-binding protein
GLO74_RS10620	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GLO74_RS10620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GLO74_RS10645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GLO74_RS10660	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GLO74_RS10670	COG0756	dUTP diphosphatase activity
GLO74_RS10800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GLO74_RS10805	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GLO74_RS10825	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GLO74_RS10830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GLO74_RS10840	COG0012	GTP binding
GLO74_RS10850	COG0592	DNA-directed DNA polymerase activity
GLO74_RS10860	COG1475	DNA binding