locus-tag	class	description
L3474_RS00010	COG0592	DNA-directed DNA polymerase activity
L3474_RS00020	COG0012	GTP binding
L3474_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L3474_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L3474_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L3474_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3474_RS00135	COG0756	dUTP diphosphatase activity
L3474_RS00145	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L3474_RS00160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L3474_RS00175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L3474_RS00175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L3474_RS00180	COG1832	CoA-binding protein
L3474_RS00190	COG2855	membrane
L3474_RS00195	COG0436	Aminotransferase
L3474_RS00200	COG1381	Involved in DNA repair and RecF pathway recombination
L3474_RS00210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3474_RS00230	COG2274	protein secretion by the type I secretion system
L3474_RS00235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3474_RS00245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L3474_RS00250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L3474_RS00260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L3474_RS00275	COG0151	Belongs to the GarS family
L3474_RS00285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L3474_RS00300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L3474_RS00305	COG3064	Membrane
L3474_RS00305	COG3525	Glycosyl hydrolase, family 20, catalytic domain
L3474_RS00305	COG3583	domain protein
L3474_RS00320	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3474_RS00325	COG3715	PTS system
L3474_RS00330	COG3716	PTS system mannose fructose sorbose family IID component
L3474_RS00340	COG2222	sugar isomerase
L3474_RS00350	COG2514	catechol 2,3-dioxygenase activity
L3474_RS00355	COG1937	Protein conserved in bacteria
L3474_RS00385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L3474_RS00390	COG0569	domain protein
L3474_RS00400	COG1215	transferase activity, transferring glycosyl groups
L3474_RS00420	COG5002	protein histidine kinase activity
L3474_RS00445	COG4209	transmembrane transport
L3474_RS00450	COG0395	ABC-type sugar transport system, permease component
L3474_RS00460	COG1653	transport
L3474_RS00495	COG1136	(ABC) transporter
L3474_RS00495	COG0577	efflux transmembrane transporter activity
L3474_RS00515	COG1695	Transcriptional regulator
L3474_RS00540	COG0546	phosphoglycolate phosphatase activity
L3474_RS00545	COG1760	l-serine dehydratase
L3474_RS00550	COG1760	l-serine dehydratase
L3474_RS00555	COG1705	Flagellar rod assembly protein muramidase FlgJ
L3474_RS00555	COG1388	LysM domain
L3474_RS00580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3474_RS00695	COG0494	nUDIX hydrolase
L3474_RS00700	COG0445	tRNA wobble uridine modification
L3474_RS00735	COG1214	PFAM Peptidase M22, glycoprotease
L3474_RS00770	COG0438	transferase activity, transferring glycosyl groups
L3474_RS00800	COG1396	sequence-specific DNA binding
L3474_RS00835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3474_RS00840	COG1464	Belongs to the NlpA lipoprotein family
L3474_RS00845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3474_RS00850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L3474_RS00870	COG2972	Histidine kinase
L3474_RS00875	COG4753	response regulator
L3474_RS00875	COG2207	Transcriptional regulator
L3474_RS00885	COG1780	Probably involved in ribonucleotide reductase function
L3474_RS00920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3474_RS00920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L3474_RS00940	COG2818	Glycosylase
L3474_RS01045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L3474_RS01050	COG0006	proline dipeptidase activity
L3474_RS01055	COG1393	Belongs to the ArsC family
L3474_RS01080	COG0285	dihydrofolate synthase activity
L3474_RS01090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L3474_RS01155	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
L3474_RS01180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
L3474_RS01220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
L3474_RS01235	COG0201	protein transport
L3474_RS01245	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
L3474_RS01250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L3474_RS01260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
L3474_RS01265	COG0202	RNA polymerase activity
L3474_RS01275	COG3830	Belongs to the UPF0237 family
L3474_RS01310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L3474_RS01315	COG1349	DNA-binding transcription factor activity
L3474_RS01325	COG1447	Phosphotransferase system cellobiose-specific component IIA
L3474_RS01330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3474_RS01335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3474_RS01340	COG1882	Formate acetyltransferase
L3474_RS01390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L3474_RS01395	COG4589	Belongs to the CDS family
L3474_RS01400	COG0750	zinc metalloprotease
L3474_RS01410	COG2723	6-phospho-beta-galactosidase activity
L3474_RS01415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L3474_RS01430	COG1523	belongs to the glycosyl hydrolase 13 family
L3474_RS01450	COG2176	DNA-directed DNA polymerase activity
L3474_RS01470	COG2309	aminopeptidase activity
L3474_RS01475	COG2261	transglycosylase associated protein
L3474_RS01480	COG1187	pseudouridine synthase activity
L3474_RS01485	COG3579	cysteine-type endopeptidase activity
L3474_RS01490	COG3716	PTS system mannose fructose sorbose family IID component
L3474_RS01495	COG3715	PTS system
L3474_RS01505	COG1064	alcohol dehydrogenase
L3474_RS01510	COG0561	phosphatase activity
L3474_RS01515	COG2252	PERMEase
L3474_RS01525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L3474_RS01530	COG0285	dihydrofolate synthase activity
L3474_RS01540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L3474_RS01540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L3474_RS01550	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
L3474_RS01575	COG0386	Belongs to the glutathione peroxidase family
L3474_RS01610	COG1028	Short-chain dehydrogenase reductase Sdr
L3474_RS01620	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
L3474_RS01625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3474_RS01630	COG3715	PTS system
L3474_RS01635	COG3716	PTS system mannose fructose sorbose family IID component
L3474_RS01650	COG1609	Transcriptional regulator
L3474_RS01685	COG4839	cell division protein FtsL
L3474_RS01690	COG0768	penicillin binding
L3474_RS01715	COG0366	Alpha amylase catalytic
L3474_RS01720	COG4166	transmembrane transport
L3474_RS01735	COG4464	protein tyrosine phosphatase activity
L3474_RS01740	COG3944	biosynthesis protein
L3474_RS01745	COG0489	protein tyrosine kinase activity
L3474_RS01760	COG3475	LICD family
L3474_RS01780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L3474_RS01785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L3474_RS01795	COG1088	dTDP-glucose 4,6-dehydratase activity
L3474_RS01800	COG1091	dTDP-4-dehydrorhamnose reductase activity
L3474_RS01810	COG4166	transmembrane transport
L3474_RS01815	COG0366	Alpha amylase catalytic
L3474_RS01820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3474_RS01845	COG0116	Belongs to the methyltransferase superfamily
L3474_RS01855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
L3474_RS01860	COG0745	RESPONSE REGULATOR receiver
L3474_RS01875	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
L3474_RS01905	COG2197	response regulator
L3474_RS01925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L3474_RS01930	COG0681	Belongs to the peptidase S26 family
L3474_RS01955	COG1115	amino acid carrier protein
L3474_RS01980	COG0527	aspartate kinase activity
L3474_RS01985	COG1024	Enoyl-CoA hydratase
L3474_RS01990	COG1846	Transcriptional regulator
L3474_RS02000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3474_RS02010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L3474_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
L3474_RS02020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L3474_RS02035	COG0439	Biotin carboxylase
L3474_RS02040	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
L3474_RS02085	COG1063	alcohol dehydrogenase
L3474_RS02110	COG1442	glycosyl transferase family 8
L3474_RS02115	COG1442	glycosyl transferase family 8
L3474_RS02120	COG0227	Belongs to the bacterial ribosomal protein bL28 family
L3474_RS02130	COG1461	Dihydroxyacetone kinase
L3474_RS02135	COG0028	Belongs to the TPP enzyme family
L3474_RS02140	COG0440	acetolactate synthase activity
L3474_RS02160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L3474_RS02175	COG0765	amino acid transport
L3474_RS02195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L3474_RS02200	COG1882	Formate acetyltransferase
L3474_RS02260	COG1940	carbohydrate kinase activity
L3474_RS02260	COG1846	Transcriptional regulator
L3474_RS02265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3474_RS02275	COG1447	Phosphotransferase system cellobiose-specific component IIA
L3474_RS02280	COG2723	6-phospho-beta-galactosidase activity
L3474_RS02285	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3474_RS02285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3474_RS02290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L3474_RS02295	COG0569	domain protein
L3474_RS02315	COG1122	ATPase activity
L3474_RS02330	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L3474_RS02335	COG0671	phosphoesterase, PA-phosphatase related
L3474_RS02345	COG1247	-acetyltransferase
L3474_RS02355	COG0504	CTP synthase activity
L3474_RS02360	COG1283	sodium-dependent phosphate transmembrane transporter activity
L3474_RS02380	COG0789	Transcriptional regulator
L3474_RS02385	COG0174	glutamine synthetase
L3474_RS02405	COG4974	Belongs to the 'phage' integrase family
L3474_RS02415	COG0732	type I restriction modification DNA specificity domain
L3474_RS02455	COG0484	heat shock protein binding
L3474_RS02470	COG0537	adenosine 5'-monophosphoramidase activity
L3474_RS02475	COG1131	(ABC) transporter
L3474_RS02480	COG4473	ABC transporter
L3474_RS02500	COG3290	protein histidine kinase activity
L3474_RS02515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3474_RS02585	COG1266	CAAX protease self-immunity
L3474_RS02605	COG0195	Participates in both transcription termination and antitermination
L3474_RS02610	COG2740	Nucleic-acid-binding protein implicated in transcription termination
L3474_RS02675	COG0519	Catalyzes the synthesis of GMP from XMP
L3474_RS02685	COG0525	valine-tRNA ligase activity
L3474_RS02715	COG3711	transcriptional antiterminator
L3474_RS02720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3474_RS02720	COG1263	PTS System
L3474_RS02720	COG2190	(PTS) system
L3474_RS02735	COG0456	acetyltransferase
L3474_RS02740	COG0072	phenylalanine-tRNA ligase activity
L3474_RS02740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3474_RS02760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
L3474_RS02775	COG1045	serine acetyltransferase
L3474_RS02785	COG0215	cysteine-tRNA ligase activity
L3474_RS02790	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
L3474_RS02810	COG0577	efflux transmembrane transporter activity
L3474_RS02815	COG1136	(ABC) transporter
L3474_RS02820	COG0577	efflux transmembrane transporter activity
L3474_RS02830	COG0745	RESPONSE REGULATOR receiver
L3474_RS02835	COG5002	protein histidine kinase activity
L3474_RS02840	COG0191	fructose-bisphosphate aldolase activity
L3474_RS02845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3474_RS02850	COG0765	amino acid transport
L3474_RS02855	COG0765	amino acid transport
L3474_RS02860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3474_RS02870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L3474_RS02870	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L3474_RS02910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3474_RS02925	COG1573	uracil-dna glycosylase
L3474_RS02935	COG1114	Component of the transport system for branched-chain amino acids
L3474_RS02940	COG1363	Peptidase, m42
L3474_RS02975	COG4555	ABC transporter
L3474_RS02995	COG1404	Belongs to the peptidase S8 family
L3474_RS03010	COG3775	system Galactitol-specific IIC component
L3474_RS03015	COG3250	beta-galactosidase activity
L3474_RS03045	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
L3474_RS03065	COG0785	Cytochrome C biogenesis protein
L3474_RS03070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3474_RS03075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L3474_RS03075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L3474_RS03080	COG2207	Transcriptional regulator
L3474_RS03080	COG4753	response regulator
L3474_RS03085	COG2972	Histidine kinase
L3474_RS03095	COG3064	Membrane
L3474_RS03100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L3474_RS03115	COG1940	carbohydrate kinase activity
L3474_RS03135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L3474_RS03140	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
L3474_RS03150	COG0300	oxidoreductase activity
L3474_RS03165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L3474_RS03175	COG1187	pseudouridine synthase activity
L3474_RS03180	COG1217	gtp-binding protein TYPA
L3474_RS03200	COG1136	(ABC) transporter
L3474_RS03215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L3474_RS03225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
L3474_RS03250	COG1131	(ABC) transporter
L3474_RS03255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3474_RS03295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
L3474_RS03305	COG1304	FMN binding
L3474_RS03320	COG0352	thiamine-phosphate diphosphorylase activity
L3474_RS03330	COG4172	Belongs to the ABC transporter superfamily
L3474_RS03340	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L3474_RS03355	COG0352	thiamine-phosphate diphosphorylase activity
L3474_RS03375	COG2217	Heavy metal translocating P-type atpase
L3474_RS03380	COG0028	Belongs to the TPP enzyme family
L3474_RS03400	COG1482	cell wall glycoprotein biosynthetic process
L3474_RS03420	COG2081	HI0933 family
L3474_RS03425	COG1307	EDD domain protein, DegV family
L3474_RS03435	COG2131	deaminase
L3474_RS03440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
L3474_RS03480	COG0617	tRNA 3'-terminal CCA addition
L3474_RS03480	COG0517	IMP dehydrogenase activity
L3474_RS03480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L3474_RS03490	COG2884	Cell division ATP-binding protein ftsE
L3474_RS03495	COG2177	Part of the ABC transporter FtsEX involved in
L3474_RS03500	COG1263	PTS System
L3474_RS03500	COG2190	(PTS) system
L3474_RS03500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3474_RS03510	COG0513	Belongs to the DEAD box helicase family
L3474_RS03520	COG0167	dihydroorotate dehydrogenase activity
L3474_RS03530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L3474_RS03535	COG4470	Protein conserved in bacteria
L3474_RS03550	COG0488	(ABC) transporter
L3474_RS03575	COG1837	Belongs to the UPF0109 family
L3474_RS03590	COG0513	Belongs to the DEAD box helicase family
L3474_RS03605	COG0726	polysaccharide deacetylase
L3474_RS03610	COG0656	L-ascorbic acid biosynthetic process
L3474_RS03635	COG3976	FMN-binding domain protein
L3474_RS03635	COG1053	succinate dehydrogenase
L3474_RS03635	COG0431	NADPH-dependent FMN reductase
L3474_RS03665	COG1272	protein, Hemolysin III
L3474_RS03680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L3474_RS03685	COG1393	Belongs to the ArsC family
L3474_RS03695	COG1126	abc transporter atp-binding protein
L3474_RS03705	COG0492	ferredoxin-NADP+ reductase activity
L3474_RS03730	COG0561	phosphatase activity
L3474_RS03745	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3474_RS03750	COG0697	spore germination
L3474_RS03755	COG2188	Transcriptional regulator
L3474_RS03775	COG1132	(ABC) transporter
L3474_RS03780	COG1132	(ABC) transporter
L3474_RS03795	COG1129	ABC transporter
L3474_RS03815	COG0826	peptidase U32
L3474_RS03830	COG1131	(ABC) transporter
L3474_RS03850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L3474_RS03860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L3474_RS03875	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
L3474_RS03910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L3474_RS03920	COG0647	UMP catabolic process
L3474_RS03930	COG1393	Belongs to the ArsC family
L3474_RS03940	COG0483	inositol monophosphate 1-phosphatase activity
L3474_RS03945	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
L3474_RS03945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L3474_RS03950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L3474_RS03955	COG0573	inorganic phosphate transmembrane transporter activity
L3474_RS03960	COG0581	inorganic phosphate transmembrane transporter activity
L3474_RS03965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L3474_RS03970	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L3474_RS03975	COG0704	Plays a role in the regulation of phosphate uptake
L3474_RS03980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3474_RS03985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3474_RS03990	COG3527	Alpha-acetolactate decarboxylase
L3474_RS04005	COG3842	ATPase activity
L3474_RS04045	COG1131	(ABC) transporter
L3474_RS04055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L3474_RS04080	COG0287	Prephenate dehydrogenase
L3474_RS04095	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
L3474_RS04100	COG0077	Prephenate dehydratase
L3474_RS04110	COG3475	LICD family
L3474_RS04120	COG1215	transferase activity, transferring glycosyl groups
L3474_RS04155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L3474_RS04155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L3474_RS04160	COG1132	(ABC) transporter
L3474_RS04170	COG0402	S-adenosylhomocysteine deaminase activity
L3474_RS04190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L3474_RS04215	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L3474_RS04220	COG0716	FMN binding
L3474_RS04225	COG1605	Chorismate mutase
L3474_RS04225	COG0077	Prephenate dehydratase
L3474_RS04230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
L3474_RS04235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
L3474_RS04260	COG1078	dGTPase activity
L3474_RS04275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L3474_RS04290	COG1704	LemA family
L3474_RS04300	COG0488	(ABC) transporter
L3474_RS04310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L3474_RS04325	COG0505	Belongs to the CarA family
L3474_RS04335	COG3475	LICD family
L3474_RS04340	COG3475	LICD family
L3474_RS04355	COG1063	alcohol dehydrogenase
L3474_RS04370	COG4750	Nucleotidyl transferase
L3474_RS04375	COG0758	DNA mediated transformation
L3474_RS04390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L3474_RS04395	COG2832	Protein of unknown function (DUF454)
L3474_RS04400	COG3142	Participates in the control of copper homeostasis
L3474_RS04420	COG0473	3-isopropylmalate dehydrogenase activity
L3474_RS04430	COG0066	3-isopropylmalate dehydratase activity
L3474_RS04440	COG1401	restriction endodeoxyribonuclease activity
L3474_RS04465	COG1196	nuclear chromosome segregation
L3474_RS04470	COG0561	phosphatase activity
L3474_RS04475	COG0561	phosphatase activity
L3474_RS04480	COG0552	protein localization to endoplasmic reticulum
L3474_RS04485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
L3474_RS04490	COG1126	abc transporter atp-binding protein
L3474_RS04495	COG0765	amino acid transport
L3474_RS04520	COG2816	NAD+ diphosphatase activity
L3474_RS04525	COG1827	regulation of RNA biosynthetic process
L3474_RS04535	COG4684	Psort location CytoplasmicMembrane, score
L3474_RS04540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L3474_RS04555	COG1194	a g-specific adenine glycosylase
L3474_RS04560	COG0745	RESPONSE REGULATOR receiver
L3474_RS04565	COG5002	protein histidine kinase activity
L3474_RS04570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L3474_RS04585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L3474_RS04600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L3474_RS04605	COG3764	Sortase (surface protein transpeptidase)
L3474_RS04625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L3474_RS04655	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
L3474_RS04660	COG1438	arginine binding
L3474_RS04665	COG0497	DNA recombination
L3474_RS04670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L3474_RS04720	COG3684	Belongs to the aldolase LacD family
L3474_RS04725	COG3711	transcriptional antiterminator
L3474_RS04740	COG2723	6-phospho-beta-galactosidase activity
L3474_RS04755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3474_RS04760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3474_RS04765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L3474_RS04770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3474_RS04785	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
L3474_RS04790	COG1011	Hydrolase
L3474_RS04805	COG1051	belongs to the nudix hydrolase family
L3474_RS04810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L3474_RS04820	COG0534	Mate efflux family protein
L3474_RS04825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L3474_RS04830	COG0022	dehydrogenase e1 component
L3474_RS04835	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3474_RS04840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3474_RS04845	COG0095	Lipoate-protein ligase
L3474_RS04865	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L3474_RS04870	COG3583	domain protein
L3474_RS04870	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
L3474_RS04925	COG0560	Phosphoserine phosphatase
L3474_RS04930	COG0560	Phosphoserine phosphatase
L3474_RS04940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L3474_RS04950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
L3474_RS04955	COG1012	belongs to the aldehyde dehydrogenase family
L3474_RS04960	COG1523	belongs to the glycosyl hydrolase 13 family
L3474_RS04980	COG0488	(ABC) transporter
L3474_RS04990	COG1307	EDD domain protein, DegV family
L3474_RS04995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L3474_RS05000	COG0196	riboflavin kinase activity
L3474_RS05040	COG0280	phosphate acetyltransferase
L3474_RS05045	COG0564	pseudouridine synthase activity
L3474_RS05055	COG2357	RelA SpoT domain protein
L3474_RS05065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L3474_RS05070	COG1104	cysteine desulfurase activity
L3474_RS05090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
L3474_RS05100	COG0210	DNA helicase
L3474_RS05110	COG0024	Methionine aminopeptidase
L3474_RS05115	COG4109	DRTGG domain
L3474_RS05125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L3474_RS05155	COG0438	transferase activity, transferring glycosyl groups
L3474_RS05160	COG0438	transferase activity, transferring glycosyl groups
L3474_RS05165	COG2151	metal-sulfur cluster biosynthetic enzyme
L3474_RS05170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L3474_RS05175	COG0358	DNA primase activity
L3474_RS05195	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
L3474_RS05200	COG0772	Belongs to the SEDS family
L3474_RS05235	COG1597	lipid kinase activity
L3474_RS05310	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3474_RS05315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3474_RS05330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L3474_RS05340	COG0741	lytic transglycosylase activity
L3474_RS05365	COG2890	protein-(glutamine-N5) methyltransferase activity
L3474_RS05375	COG1435	thymidine kinase activity
L3474_RS05380	COG1942	4-Oxalocrotonate Tautomerase
L3474_RS05395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L3474_RS05405	COG4708	membrane
L3474_RS05415	COG1970	mechanosensitive ion channel activity
L3474_RS05430	COG4509	Sortase family
L3474_RS05440	COG0681	Belongs to the peptidase S26 family
L3474_RS05480	COG3443	Belongs to the bacterial solute-binding protein 9 family
L3474_RS05480	COG0803	Belongs to the bacterial solute-binding protein 9 family
L3474_RS05485	COG0531	amino acid
L3474_RS05490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3474_RS05495	COG0785	Cytochrome C biogenesis protein
L3474_RS05520	COG0584	glycerophosphoryl diester phosphodiesterase
L3474_RS05525	COG2176	DNA-directed DNA polymerase activity
L3474_RS05535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L3474_RS05545	COG0494	nUDIX hydrolase
L3474_RS05565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L3474_RS05590	COG4122	O-methyltransferase activity
L3474_RS05605	COG3615	Tellurite resistance protein tehB
L3474_RS05605	COG0500	methyltransferase
L3474_RS05615	COG0557	exoribonuclease II activity
L3474_RS05630	COG2814	Major facilitator Superfamily
L3474_RS05635	COG0237	dephospho-CoA kinase activity
L3474_RS05640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L3474_RS05650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L3474_RS05660	COG1293	RNA-binding protein homologous to eukaryotic snRNP
L3474_RS05665	COG5263	repeat protein
L3474_RS05665	COG4193	domain, Protein
L3474_RS05670	COG0167	dihydroorotate dehydrogenase activity
L3474_RS05675	COG0543	2 iron, 2 sulfur cluster binding
L3474_RS05705	COG1131	(ABC) transporter
L3474_RS05715	COG2333	competence protein COMEC
L3474_RS05715	COG0658	competence protein
L3474_RS05720	COG1555	photosystem II stabilization
L3474_RS05720	COG1596	polysaccharide export
L3474_RS05725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L3474_RS05745	COG1702	phosphate starvation-inducible protein PhoH
L3474_RS05755	COG2996	Protein conserved in bacteria
L3474_RS05765	COG0528	UMP kinase activity
L3474_RS05785	COG0470	DNA polymerase III
L3474_RS05795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L3474_RS05810	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
L3474_RS05815	COG0564	pseudouridine synthase activity
L3474_RS05820	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
L3474_RS05825	COG0583	DNA-binding transcription factor activity
L3474_RS05845	COG0561	phosphatase activity
L3474_RS05850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L3474_RS05870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
L3474_RS05890	COG1982	Orn Lys Arg decarboxylase major
L3474_RS05905	COG0577	efflux transmembrane transporter activity
L3474_RS05910	COG1136	(ABC) transporter
L3474_RS05930	COG2183	response to ionizing radiation
L3474_RS05940	COG0701	Predicted permease
L3474_RS05945	COG3689	TIGRFAM TIGR03943 family protein
L3474_RS05980	COG0469	pyruvate kinase activity
L3474_RS06000	COG1438	arginine binding
L3474_RS06010	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
L3474_RS06060	COG1104	cysteine desulfurase activity
L3474_RS06070	COG1674	ftsk spoiiie
L3474_RS06070	COG0697	spore germination
L3474_RS06075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3474_RS06075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3474_RS06075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3474_RS06080	COG1105	Belongs to the carbohydrate kinase PfkB family
L3474_RS06085	COG1349	DNA-binding transcription factor activity
L3474_RS06100	COG0628	permease
L3474_RS06105	COG1686	Belongs to the peptidase S11 family
L3474_RS06110	COG0719	Fe-S assembly protein
L3474_RS06120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L3474_RS06125	COG0719	Fe-S assembly protein
L3474_RS06140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L3474_RS06145	COG1956	GAF domain-containing protein
L3474_RS06150	COG0539	negative regulation of cytoplasmic translation
L3474_RS06185	COG4166	transmembrane transport
L3474_RS06190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L3474_RS06195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L3474_RS06205	COG0187	DNA topoisomerase II activity
L3474_RS06220	COG1079	Belongs to the binding-protein-dependent transport system permease family
L3474_RS06225	COG4603	Belongs to the binding-protein-dependent transport system permease family
L3474_RS06230	COG3845	ABC transporter
L3474_RS06235	COG1744	ABC transporter substrate-binding protein PnrA-like
L3474_RS06240	COG0295	cytidine deaminase activity
L3474_RS06250	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L3474_RS06255	COG2813	Specifically methylates the guanine in position
L3474_RS06300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
L3474_RS06320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L3474_RS06325	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
L3474_RS06330	COG1126	abc transporter atp-binding protein
L3474_RS06335	COG0765	amino acid transport
L3474_RS06340	COG4703	Protein of unknown function (DUF1797)
L3474_RS06345	COG0542	response to heat
L3474_RS06355	COG0494	nUDIX hydrolase
L3474_RS06385	COG0187	DNA topoisomerase II activity
L3474_RS06395	COG0693	protein deglycase activity
L3474_RS06400	COG0772	Belongs to the SEDS family
L3474_RS06420	COG5002	protein histidine kinase activity
L3474_RS06425	COG0745	RESPONSE REGULATOR receiver
L3474_RS06450	COG1028	Short-chain dehydrogenase reductase Sdr
L3474_RS06460	COG4989	oxidoreductase activity
L3474_RS06480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3474_RS06480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3474_RS06485	COG0577	efflux transmembrane transporter activity
L3474_RS06490	COG1136	(ABC) transporter
L3474_RS06495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3474_RS06500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3474_RS06505	COG1268	BioY protein
L3474_RS06515	COG4443	Transcriptional Coactivator p15 (PC4)
L3474_RS06525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
L3474_RS06525	COG1328	CTP reductase activity
L3474_RS06560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L3474_RS06585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L3474_RS06595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3474_RS06600	COG1126	abc transporter atp-binding protein
L3474_RS06615	COG0628	permease
L3474_RS06620	COG2706	6-phosphogluconolactonase activity
L3474_RS06685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L3474_RS06710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L3474_RS06715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L3474_RS06720	COG0626	cystathionine gamma-synthase activity
L3474_RS06725	COG1132	(ABC) transporter
L3474_RS06740	COG4166	transmembrane transport
L3474_RS06745	COG2244	polysaccharide biosynthetic process
L3474_RS06750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L3474_RS06775	COG2827	Endonuclease containing a URI domain
L3474_RS06780	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L3474_RS06785	COG1098	S1 RNA binding domain
L3474_RS06795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
L3474_RS06800	COG0629	single-stranded DNA binding
L3474_RS06810	COG0017	Asparaginyl-tRNA synthetase
L3474_RS06820	COG0436	Aminotransferase
L3474_RS06840	COG3711	transcriptional antiterminator
L3474_RS06860	COG0242	peptide deformylase activity
L3474_RS06865	COG0625	glutathione transferase activity
L3474_RS06880	COG0488	(ABC) transporter
L3474_RS06885	COG0617	tRNA 3'-terminal CCA addition
L3474_RS06895	COG1307	EDD domain protein, DegV family
L3474_RS06915	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L3474_RS06925	COG1481	regulation of sporulation
L3474_RS06930	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L3474_RS06940	COG0251	oxidation-reduction process
L3474_RS06960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L3474_RS06970	COG4193	domain, Protein
L3474_RS06970	COG5263	repeat protein
L3474_RS06980	COG3935	DnaD domain protein
L3474_RS06995	COG2226	methyltransferase
L3474_RS07005	COG3842	ATPase activity
L3474_RS07015	COG1335	isochorismatase
L3474_RS07025	COG0513	Belongs to the DEAD box helicase family
L3474_RS07030	COG2223	nitrite transmembrane transporter activity
L3474_RS07035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3474_RS07040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L3474_RS07045	COG3442	glutamine amidotransferase
L3474_RS07050	COG0006	proline dipeptidase activity
L3474_RS07065	COG4720	Psort location CytoplasmicMembrane, score
L3474_RS07070	COG0351	phosphomethylpyrimidine kinase
L3474_RS07090	COG2824	Alkylphosphonate utilization operon protein PhnA
L3474_RS07110	COG0463	Glycosyl transferase, family 2
L3474_RS07115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L3474_RS07125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3474_RS07130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L3474_RS07135	COG2384	SAM-dependent methyltransferase
L3474_RS07155	COG2801	Transposase and inactivated derivatives
L3474_RS07160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L3474_RS07165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L3474_RS07170	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L3474_RS07170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3474_RS07170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3474_RS07175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3474_RS07195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L3474_RS07200	COG0204	Acyl-transferase
L3474_RS07215	COG2910	NAD(P)H-binding
L3474_RS07240	COG5002	protein histidine kinase activity
L3474_RS07245	COG0745	RESPONSE REGULATOR receiver
L3474_RS07260	COG1959	2 iron, 2 sulfur cluster binding
L3474_RS07320	COG3590	peptidase
L3474_RS07335	COG0803	Belongs to the bacterial solute-binding protein 9 family
L3474_RS07340	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
L3474_RS07380	COG3599	regulation of cell shape
L3474_RS07400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L3474_RS07420	COG1051	belongs to the nudix hydrolase family
L3474_RS07425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L3474_RS07440	COG0768	penicillin binding
L3474_RS07455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3474_RS07475	COG2731	YhcH YjgK YiaL family protein
L3474_RS07480	COG0395	ABC-type sugar transport system, permease component
L3474_RS07485	COG1175	transmembrane transport
L3474_RS07495	COG1263	PTS System
L3474_RS07495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3474_RS07495	COG2190	(PTS) system
L3474_RS07505	COG0673	inositol 2-dehydrogenase activity
L3474_RS07510	COG4409	exo-alpha-(2->6)-sialidase activity
L3474_RS07520	COG1175	transmembrane transport
L3474_RS07525	COG1653	transport
L3474_RS07550	COG3458	cephalosporin-C deacetylase activity
L3474_RS07555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L3474_RS07570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L3474_RS07575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L3474_RS07590	COG1131	(ABC) transporter
L3474_RS07620	COG0778	Nitroreductase
L3474_RS07625	COG1484	DNA-dependent DNA replication
L3474_RS07640	COG1725	Transcriptional regulator
L3474_RS07645	COG1131	(ABC) transporter
L3474_RS07655	COG1668	transmembrane transport
L3474_RS07660	COG4152	abc transporter atp-binding protein
L3474_RS07680	COG1940	carbohydrate kinase activity
L3474_RS07685	COG1263	PTS System
L3474_RS07685	COG2190	(PTS) system
L3474_RS07685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3474_RS07690	COG1621	beta-fructofuranosidase activity
L3474_RS07695	COG1609	Transcriptional regulator
L3474_RS07705	COG3425	synthase
L3474_RS07730	COG0515	serine threonine protein kinase
L3474_RS07730	COG2815	serine threonine protein kinase
L3474_RS07735	COG0631	protein serine/threonine phosphatase activity
L3474_RS07740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L3474_RS07740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L3474_RS07750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L3474_RS07760	COG0194	GDP metabolic process
L3474_RS07780	COG2226	methyltransferase
L3474_RS07785	COG0799	negative regulation of ribosome biogenesis
L3474_RS07795	COG1713	HD superfamily hydrolase involved in NAD metabolism
L3474_RS07800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
L3474_RS07805	COG1534	Rna-binding protein
L3474_RS07810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L3474_RS07825	COG0668	transmembrane transport
L3474_RS07850	COG3118	belongs to the thioredoxin family
L3474_RS07855	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
L3474_RS07865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L3474_RS07875	COG1164	Oligoendopeptidase f
L3474_RS07880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L3474_RS07940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L3474_RS07950	COG1621	beta-fructofuranosidase activity
L3474_RS07955	COG1653	transport
L3474_RS07960	COG0395	ABC-type sugar transport system, permease component
L3474_RS07965	COG4209	transmembrane transport
L3474_RS07975	COG3711	transcriptional antiterminator
L3474_RS07980	COG2261	transglycosylase associated protein
L3474_RS08000	COG3237	CsbD-like
L3474_RS08015	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L3474_RS08060	COG0512	Glutamine amidotransferase of anthranilate synthase
L3474_RS08065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L3474_RS08085	COG1285	pathogenesis
L3474_RS08090	COG1178	ABC-type Fe3 transport system permease component
L3474_RS08110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L3474_RS08115	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
L3474_RS08120	COG0704	Plays a role in the regulation of phosphate uptake
L3474_RS08130	COG5434	Belongs to the glycosyl hydrolase 28 family
L3474_RS08135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L3474_RS08140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L3474_RS08145	COG1132	(ABC) transporter
L3474_RS08150	COG1132	(ABC) transporter
L3474_RS08165	COG0708	Exodeoxyribonuclease III
L3474_RS08185	COG2233	PERMEase
L3474_RS08210	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
L3474_RS08215	COG1609	Transcriptional regulator
L3474_RS08220	COG1063	alcohol dehydrogenase
L3474_RS08225	COG0789	Transcriptional regulator
L3474_RS08230	COG1230	cation diffusion facilitator family transporter
L3474_RS08240	COG3201	nicotinamide mononucleotide transporter
L3474_RS08245	COG1174	glycine betaine transport
L3474_RS08270	COG1363	Peptidase, m42
L3474_RS08285	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3474_RS08290	COG4605	iron ion homeostasis
L3474_RS08295	COG4604	ABC transporter, ATP-binding protein
L3474_RS08300	COG4607	ABC-type enterochelin transport system periplasmic component
L3474_RS08310	COG1187	pseudouridine synthase activity
L3474_RS08330	COG0517	IMP dehydrogenase activity
L3474_RS08340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
L3474_RS08355	COG0366	Alpha amylase catalytic
L3474_RS08360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3474_RS08360	COG1263	PTS System
L3474_RS08365	COG2188	Transcriptional regulator
L3474_RS08385	COG4608	Belongs to the ABC transporter superfamily
L3474_RS08390	COG0444	Belongs to the ABC transporter superfamily
L3474_RS08395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3474_RS08400	COG0601	transmembrane transport
L3474_RS08405	COG4166	transmembrane transport
L3474_RS08415	COG0366	Alpha amylase catalytic
L3474_RS08425	COG0395	ABC-type sugar transport system, permease component
L3474_RS08430	COG1175	transmembrane transport
L3474_RS08435	COG1653	transport
L3474_RS08440	COG3345	alpha-galactosidase
L3474_RS08445	COG2207	Transcriptional regulator
L3474_RS08450	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
L3474_RS08450	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
L3474_RS08565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L3474_RS08615	COG4221	oxidoreductase activity
L3474_RS08620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3474_RS08625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3474_RS08665	COG1132	(ABC) transporter
L3474_RS08720	COG3842	ATPase activity
L3474_RS08725	COG1178	ABC-type Fe3 transport system permease component
L3474_RS08730	COG1285	pathogenesis
L3474_RS08790	COG5263	repeat protein
L3474_RS08790	COG5632	N-Acetylmuramoyl-L-alanine amidase
L3474_RS08810	COG1316	TRANSCRIPTIONal
L3474_RS08820	COG0802	atpase or kinase
L3474_RS08850	COG1674	ftsk spoiiie
L3474_RS08860	COG2946	Replication initiation factor
L3474_RS08910	COG0791	NLP P60 protein
L3474_RS08910	COG0741	lytic transglycosylase activity
L3474_RS08950	COG0488	(ABC) transporter
L3474_RS09005	COG1136	(ABC) transporter
L3474_RS09005	COG0577	efflux transmembrane transporter activity
L3474_RS09030	COG1253	flavin adenine dinucleotide binding
L3474_RS09045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L3474_RS09055	COG3480	Lon protease (S16) C-terminal proteolytic domain
L3474_RS09065	COG0742	ribosomal rna small subunit methyltransferase
L3474_RS09080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3474_RS09085	COG1254	Belongs to the acylphosphatase family
L3474_RS09095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L3474_RS09105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L3474_RS09120	COG1564	THIamine pyrophosphokinase
L3474_RS09130	COG1162	GTPase activity
L3474_RS09160	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L3474_RS09165	COG0084	hydrolase, TatD family'
L3474_RS09180	COG0436	Aminotransferase
L3474_RS09190	COG0589	response to stress
L3474_RS09195	COG0561	phosphatase activity
L3474_RS09200	COG0252	asparaginase activity
L3474_RS09210	COG1609	Transcriptional regulator
L3474_RS09215	COG2197	response regulator
L3474_RS09220	COG4585	Histidine kinase
L3474_RS09225	COG0842	Transport permease protein
L3474_RS09230	COG1131	(ABC) transporter
L3474_RS09335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L3474_RS09340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3474_RS09345	COG0564	pseudouridine synthase activity
L3474_RS09355	COG0577	efflux transmembrane transporter activity
L3474_RS09365	COG0157	Belongs to the NadC ModD family
L3474_RS09380	COG1129	ABC transporter
L3474_RS09385	COG2188	Transcriptional regulator
L3474_RS09390	COG2723	6-phospho-beta-galactosidase activity
L3474_RS09395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3474_RS09405	COG1447	Phosphotransferase system cellobiose-specific component IIA
L3474_RS09410	COG1454	alcohol dehydrogenase
L3474_RS09410	COG1012	belongs to the aldehyde dehydrogenase family
L3474_RS09420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L3474_RS09430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L3474_RS09450	COG3623	hexulose-6-phosphate isomerase
L3474_RS09460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3474_RS09470	COG3037	sugar-specific permease SgaT UlaA
L3474_RS09480	COG1847	R3H domain protein
L3474_RS09485	COG0706	membrane insertase activity
L3474_RS09535	COG4537	Required for transformation and DNA binding
L3474_RS09540	COG1459	type II secretion system
L3474_RS09545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L3474_RS09555	COG1063	alcohol dehydrogenase
L3474_RS09580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
L3474_RS09585	COG3759	membrane
L3474_RS09600	COG0131	Imidazoleglycerol-phosphate dehydratase
L3474_RS09600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L3474_RS09605	COG0534	Mate efflux family protein
L3474_RS09720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
L3474_RS09725	COG1132	(ABC) transporter
L3474_RS09735	COG1132	(ABC) transporter
L3474_RS09745	COG1438	arginine binding
L3474_RS09765	COG0745	RESPONSE REGULATOR receiver
L3474_RS09770	COG5002	protein histidine kinase activity
L3474_RS09775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L3474_RS09780	COG0573	inorganic phosphate transmembrane transporter activity
L3474_RS09790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L3474_RS09795	COG0704	Plays a role in the regulation of phosphate uptake
L3474_RS09820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L3474_RS09830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L3474_RS09845	COG0697	spore germination
L3474_RS09850	COG4499	WXG100 protein secretion system (Wss), protein YukC
L3474_RS09850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3474_RS09860	COG2217	Heavy metal translocating P-type atpase
L3474_RS09870	COG2226	methyltransferase
L3474_RS09880	COG0058	SHG alpha-glucan phosphorylase activity
L3474_RS09885	COG1640	4-alpha-glucanotransferase
L3474_RS09890	COG2182	Extracellular solute-binding protein
L3474_RS09895	COG1175	transmembrane transport
L3474_RS09900	COG3833	ABC-type maltose transport systems, permease component
L3474_RS09905	COG5521	maltodextrose utilization protein MalA
L3474_RS09910	COG1609	Transcriptional regulator
L3474_RS09915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L3474_RS09950	COG1476	TRANSCRIPTIONal
L3474_RS09975	COG1396	sequence-specific DNA binding
L3474_RS09980	COG2151	metal-sulfur cluster biosynthetic enzyme
L3474_RS09995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
L3474_RS10000	COG3959	Transketolase, thiamine diphosphate binding domain
L3474_RS10015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3474_RS10035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L3474_RS10070	COG0383	alpha-mannosidase activity
L3474_RS10080	COG3537	Alpha-1,2-mannosidase
L3474_RS10100	COG0549	Belongs to the carbamate kinase family
L3474_RS10105	COG1288	antiporter activity
L3474_RS10110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3474_RS10120	COG3064	Membrane
L3474_RS10120	COG3525	Glycosyl hydrolase, family 20, catalytic domain
L3474_RS10120	COG3583	domain protein
L3474_RS10135	COG1454	alcohol dehydrogenase
L3474_RS10155	COG3716	PTS system mannose fructose sorbose family IID component
L3474_RS10165	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3474_RS10185	COG1070	Carbohydrate kinase
L3474_RS10195	COG3443	Belongs to the bacterial solute-binding protein 9 family
L3474_RS10195	COG0803	Belongs to the bacterial solute-binding protein 9 family
L3474_RS10200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L3474_RS10205	COG1121	(ABC) transporter
L3474_RS10210	COG1846	Transcriptional regulator
L3474_RS10215	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L3474_RS10225	COG1696	Membrane protein involved in D-alanine export
L3474_RS10240	COG2211	Major facilitator Superfamily
L3474_RS10260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L3474_RS10265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L3474_RS10285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L3474_RS10305	COG1755	Isoprenylcysteine carboxyl methyltransferase
L3474_RS10310	COG5002	protein histidine kinase activity
L3474_RS10315	COG0745	RESPONSE REGULATOR receiver
L3474_RS10320	COG0542	response to heat
L3474_RS10325	COG4463	regulation of RNA biosynthetic process
L3474_RS10330	COG1116	anion transmembrane transporter activity
L3474_RS10335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L3474_RS10340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3474_RS10360	COG0305	Participates in initiation and elongation during chromosome replication
L3474_RS10380	COG1040	competence protein
L3474_RS10385	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
L3474_RS10390	COG1739	Uncharacterized protein family UPF0029
L3474_RS10425	COG3942	CHAP domain
L3474_RS10435	COG1792	Involved in formation and maintenance of cell shape
L3474_RS10440	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L3474_RS10445	COG1122	ATPase activity
L3474_RS10450	COG1122	ATPase activity
L3474_RS10455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L3474_RS10465	COG0612	Peptidase, M16
L3474_RS10470	COG0612	Peptidase, M16
L3474_RS10475	COG2501	S4 domain
L3474_RS10485	COG0516	GMP reductase activity
L3474_RS10485	COG0517	IMP dehydrogenase activity
L3474_RS10490	COG0180	Tryptophanyl-tRNA synthetase
L3474_RS10495	COG0488	(ABC) transporter
L3474_RS10505	COG1511	domain protein
L3474_RS10510	COG1511	domain protein
L3474_RS10555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3474_RS10560	COG1475	DNA binding