locus-tag	class	description
GL185_RS00015	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GL185_RS00035	COG1307	EDD domain protein, DegV family
GL185_RS00050	COG0488	(ABC) transporter
GL185_RS00055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GL185_RS00065	COG0625	glutathione transferase activity
GL185_RS00070	COG0242	peptide deformylase activity
GL185_RS00090	COG3711	transcriptional antiterminator
GL185_RS00110	COG0436	Aminotransferase
GL185_RS00120	COG0017	Asparaginyl-tRNA synthetase
GL185_RS00130	COG0629	single-stranded DNA binding
GL185_RS00135	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GL185_RS00145	COG1098	S1 RNA binding domain
GL185_RS00150	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GL185_RS00155	COG2827	Endonuclease containing a URI domain
GL185_RS00180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GL185_RS00185	COG2244	polysaccharide biosynthetic process
GL185_RS00190	COG4166	transmembrane transport
GL185_RS00195	COG1132	(ABC) transporter
GL185_RS00200	COG1132	(ABC) transporter
GL185_RS00205	COG0626	cystathionine gamma-synthase activity
GL185_RS00210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GL185_RS00215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GL185_RS00240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GL185_RS00305	COG2706	6-phosphogluconolactonase activity
GL185_RS00310	COG0628	permease
GL185_RS00325	COG1126	abc transporter atp-binding protein
GL185_RS00330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL185_RS00340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GL185_RS00375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GL185_RS00390	COG0513	Belongs to the DEAD box helicase family
GL185_RS00405	COG0726	polysaccharide deacetylase
GL185_RS00415	COG0656	L-ascorbic acid biosynthetic process
GL185_RS00440	COG0431	NADPH-dependent FMN reductase
GL185_RS00440	COG1053	succinate dehydrogenase
GL185_RS00440	COG3976	FMN-binding domain protein
GL185_RS00470	COG1272	protein, Hemolysin III
GL185_RS00490	COG1393	Belongs to the ArsC family
GL185_RS00500	COG1126	abc transporter atp-binding protein
GL185_RS00510	COG0492	ferredoxin-NADP+ reductase activity
GL185_RS00535	COG0561	phosphatase activity
GL185_RS00550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GL185_RS00555	COG0697	spore germination
GL185_RS00560	COG2188	Transcriptional regulator
GL185_RS00600	COG1129	ABC transporter
GL185_RS00615	COG1132	(ABC) transporter
GL185_RS00645	COG0826	peptidase U32
GL185_RS00680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GL185_RS00690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GL185_RS00740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GL185_RS00750	COG0647	UMP catabolic process
GL185_RS00760	COG1393	Belongs to the ArsC family
GL185_RS00770	COG0483	inositol monophosphate 1-phosphatase activity
GL185_RS00775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GL185_RS00775	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GL185_RS00780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GL185_RS00785	COG0573	inorganic phosphate transmembrane transporter activity
GL185_RS00790	COG0581	inorganic phosphate transmembrane transporter activity
GL185_RS00795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GL185_RS00800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GL185_RS00805	COG0704	Plays a role in the regulation of phosphate uptake
GL185_RS00810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL185_RS00815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GL185_RS00820	COG3527	Alpha-acetolactate decarboxylase
GL185_RS00835	COG3842	ATPase activity
GL185_RS00875	COG4555	ABC transporter
GL185_RS00885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GL185_RS00910	COG0287	Prephenate dehydrogenase
GL185_RS00925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GL185_RS00930	COG0077	Prephenate dehydratase
GL185_RS00940	COG3475	LICD family
GL185_RS00950	COG1215	transferase activity, transferring glycosyl groups
GL185_RS00985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GL185_RS00985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GL185_RS00990	COG1132	(ABC) transporter
GL185_RS01000	COG0402	S-adenosylhomocysteine deaminase activity
GL185_RS01025	COG0515	serine threonine protein kinase
GL185_RS01035	COG1136	(ABC) transporter
GL185_RS01035	COG0577	efflux transmembrane transporter activity
GL185_RS01060	COG1737	Transcriptional regulator
GL185_RS01065	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GL185_RS01070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GL185_RS01075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GL185_RS01085	COG4409	exo-alpha-(2->6)-sialidase activity
GL185_RS01090	COG0673	inositol 2-dehydrogenase activity
GL185_RS01105	COG1269	ATP hydrolysis coupled proton transport
GL185_RS01110	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GL185_RS01190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GL185_RS01220	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GL185_RS01225	COG0716	FMN binding
GL185_RS01230	COG1605	Chorismate mutase
GL185_RS01230	COG0077	Prephenate dehydratase
GL185_RS01235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GL185_RS01240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GL185_RS01260	COG1078	dGTPase activity
GL185_RS01275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GL185_RS01290	COG1704	LemA family
GL185_RS01300	COG0488	(ABC) transporter
GL185_RS01315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GL185_RS01330	COG0505	Belongs to the CarA family
GL185_RS01340	COG3475	LICD family
GL185_RS01345	COG3475	LICD family
GL185_RS01355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GL185_RS01360	COG1063	alcohol dehydrogenase
GL185_RS01375	COG4750	Nucleotidyl transferase
GL185_RS01380	COG0758	DNA mediated transformation
GL185_RS01390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GL185_RS01395	COG2832	Protein of unknown function (DUF454)
GL185_RS01400	COG3142	Participates in the control of copper homeostasis
GL185_RS01420	COG0473	3-isopropylmalate dehydrogenase activity
GL185_RS01430	COG0066	3-isopropylmalate dehydratase activity
GL185_RS01440	COG1401	restriction endodeoxyribonuclease activity
GL185_RS01465	COG1196	nuclear chromosome segregation
GL185_RS01470	COG0561	phosphatase activity
GL185_RS01475	COG0561	phosphatase activity
GL185_RS01480	COG0552	protein localization to endoplasmic reticulum
GL185_RS01485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GL185_RS01490	COG1126	abc transporter atp-binding protein
GL185_RS01495	COG0765	amino acid transport
GL185_RS01520	COG2816	NAD+ diphosphatase activity
GL185_RS01525	COG1827	regulation of RNA biosynthetic process
GL185_RS01535	COG4684	Psort location CytoplasmicMembrane, score
GL185_RS01540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GL185_RS01555	COG1194	a g-specific adenine glycosylase
GL185_RS01560	COG0745	RESPONSE REGULATOR receiver
GL185_RS01565	COG5002	protein histidine kinase activity
GL185_RS01570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GL185_RS01600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GL185_RS01605	COG3764	Sortase (surface protein transpeptidase)
GL185_RS01625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GL185_RS01655	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GL185_RS01660	COG1438	arginine binding
GL185_RS01665	COG0497	DNA recombination
GL185_RS01670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GL185_RS01735	COG1396	sequence-specific DNA binding
GL185_RS01740	COG0542	response to heat
GL185_RS01770	COG3843	relaxase mobilization nuclease domain protein
GL185_RS01785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GL185_RS01805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GL185_RS01810	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GL185_RS01860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GL185_RS01885	COG1597	lipid kinase activity
GL185_RS01890	COG0366	Alpha amylase catalytic
GL185_RS01900	COG1396	sequence-specific DNA binding
GL185_RS01905	COG0542	response to heat
GL185_RS01925	COG3843	relaxase mobilization nuclease domain protein
GL185_RS01955	COG1131	(ABC) transporter
GL185_RS01980	COG0772	Belongs to the SEDS family
GL185_RS01985	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GL185_RS02000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GL185_RS02005	COG0358	DNA primase activity
GL185_RS02010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GL185_RS02015	COG2151	metal-sulfur cluster biosynthetic enzyme
GL185_RS02020	COG0438	transferase activity, transferring glycosyl groups
GL185_RS02025	COG0438	transferase activity, transferring glycosyl groups
GL185_RS02050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GL185_RS02060	COG4109	DRTGG domain
GL185_RS02065	COG0024	Methionine aminopeptidase
GL185_RS02075	COG0210	DNA helicase
GL185_RS02085	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GL185_RS02105	COG1104	cysteine desulfurase activity
GL185_RS02110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GL185_RS02120	COG2357	RelA SpoT domain protein
GL185_RS02130	COG0564	pseudouridine synthase activity
GL185_RS02135	COG0280	phosphate acetyltransferase
GL185_RS02175	COG0196	riboflavin kinase activity
GL185_RS02180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GL185_RS02185	COG1307	EDD domain protein, DegV family
GL185_RS02195	COG0488	(ABC) transporter
GL185_RS02205	COG2814	Major facilitator Superfamily
GL185_RS02215	COG1523	belongs to the glycosyl hydrolase 13 family
GL185_RS02220	COG1012	belongs to the aldehyde dehydrogenase family
GL185_RS02225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GL185_RS02235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GL185_RS02245	COG0560	Phosphoserine phosphatase
GL185_RS02250	COG0560	Phosphoserine phosphatase
GL185_RS02270	COG0582	viral genome integration into host DNA
GL185_RS02290	COG1074	ATP-dependent DNA helicase activity
GL185_RS02300	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GL185_RS02300	COG3583	domain protein
GL185_RS02305	COG3064	Membrane
GL185_RS02310	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GL185_RS02330	COG0095	Lipoate-protein ligase
GL185_RS02335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GL185_RS02340	COG0508	dehydrogenase complex catalyzes the overall conversion of
GL185_RS02345	COG0022	dehydrogenase e1 component
GL185_RS02350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GL185_RS02355	COG0534	Mate efflux family protein
GL185_RS02365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GL185_RS02370	COG1051	belongs to the nudix hydrolase family
GL185_RS02385	COG1011	Hydrolase
GL185_RS02390	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GL185_RS02410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL185_RS02415	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GL185_RS02420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GL185_RS02425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GL185_RS02455	COG3711	transcriptional antiterminator
GL185_RS02460	COG3684	Belongs to the aldolase LacD family
GL185_RS02535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GL185_RS02545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GL185_RS02550	COG1396	sequence-specific DNA binding
GL185_RS02615	COG1674	ftsk spoiiie
GL185_RS02625	COG2946	Replication initiation factor
GL185_RS02670	COG0791	NLP P60 protein
GL185_RS02670	COG0741	lytic transglycosylase activity
GL185_RS02685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GL185_RS02740	COG0270	DNA (cytosine-5-)-methyltransferase activity
GL185_RS02755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GL185_RS02765	COG0741	lytic transglycosylase activity
GL185_RS02790	COG2890	protein-(glutamine-N5) methyltransferase activity
GL185_RS02795	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GL185_RS02800	COG1435	thymidine kinase activity
GL185_RS02805	COG1942	4-Oxalocrotonate Tautomerase
GL185_RS02810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GL185_RS02820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GL185_RS02830	COG4708	membrane
GL185_RS02840	COG1970	mechanosensitive ion channel activity
GL185_RS02890	COG3443	Belongs to the bacterial solute-binding protein 9 family
GL185_RS02890	COG0803	Belongs to the bacterial solute-binding protein 9 family
GL185_RS02895	COG0531	amino acid
GL185_RS02900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GL185_RS02905	COG0785	Cytochrome C biogenesis protein
GL185_RS02925	COG0584	glycerophosphoryl diester phosphodiesterase
GL185_RS02930	COG2176	DNA-directed DNA polymerase activity
GL185_RS02940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GL185_RS02950	COG0494	nUDIX hydrolase
GL185_RS02955	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GL185_RS02970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GL185_RS02995	COG4122	O-methyltransferase activity
GL185_RS03010	COG0500	methyltransferase
GL185_RS03010	COG3615	Tellurite resistance protein tehB
GL185_RS03020	COG0557	exoribonuclease II activity
GL185_RS03030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GL185_RS03035	COG2814	Major facilitator Superfamily
GL185_RS03040	COG0237	dephospho-CoA kinase activity
GL185_RS03045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GL185_RS03055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GL185_RS03065	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GL185_RS03070	COG5263	repeat protein
GL185_RS03070	COG4193	domain, Protein
GL185_RS03075	COG0167	dihydroorotate dehydrogenase activity
GL185_RS03080	COG0543	2 iron, 2 sulfur cluster binding
GL185_RS03110	COG1131	(ABC) transporter
GL185_RS03120	COG0658	competence protein
GL185_RS03120	COG2333	competence protein COMEC
GL185_RS03125	COG1596	polysaccharide export
GL185_RS03125	COG1555	photosystem II stabilization
GL185_RS03130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GL185_RS03135	COG0686	Belongs to the AlaDH PNT family
GL185_RS03140	COG0686	Belongs to the AlaDH PNT family
GL185_RS03145	COG0686	Belongs to the AlaDH PNT family
GL185_RS03165	COG1702	phosphate starvation-inducible protein PhoH
GL185_RS03175	COG2996	Protein conserved in bacteria
GL185_RS03185	COG0528	UMP kinase activity
GL185_RS03225	COG0470	DNA polymerase III
GL185_RS03235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GL185_RS03250	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GL185_RS03255	COG0564	pseudouridine synthase activity
GL185_RS03260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GL185_RS03265	COG0583	DNA-binding transcription factor activity
GL185_RS03285	COG0561	phosphatase activity
GL185_RS03290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GL185_RS03310	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GL185_RS03320	COG1982	Orn Lys Arg decarboxylase major
GL185_RS03335	COG0577	efflux transmembrane transporter activity
GL185_RS03340	COG1136	(ABC) transporter
GL185_RS03360	COG2183	response to ionizing radiation
GL185_RS03370	COG0701	Predicted permease
GL185_RS03375	COG3689	TIGRFAM TIGR03943 family protein
GL185_RS03405	COG0582	viral genome integration into host DNA
GL185_RS03410	COG0469	pyruvate kinase activity
GL185_RS03430	COG1438	arginine binding
GL185_RS03440	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GL185_RS03500	COG1104	cysteine desulfurase activity
GL185_RS03510	COG0697	spore germination
GL185_RS03510	COG1674	ftsk spoiiie
GL185_RS03515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GL185_RS03515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL185_RS03515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GL185_RS03520	COG1105	Belongs to the carbohydrate kinase PfkB family
GL185_RS03525	COG1349	DNA-binding transcription factor activity
GL185_RS03540	COG0628	permease
GL185_RS03545	COG1686	Belongs to the peptidase S11 family
GL185_RS03550	COG0719	Fe-S assembly protein
GL185_RS03560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GL185_RS03565	COG0719	Fe-S assembly protein
GL185_RS03580	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GL185_RS03585	COG1956	GAF domain-containing protein
GL185_RS03595	COG0539	negative regulation of cytoplasmic translation
GL185_RS03630	COG4166	transmembrane transport
GL185_RS03635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GL185_RS03640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GL185_RS03650	COG0187	DNA topoisomerase II activity
GL185_RS03665	COG1079	Belongs to the binding-protein-dependent transport system permease family
GL185_RS03670	COG4603	Belongs to the binding-protein-dependent transport system permease family
GL185_RS03675	COG3845	ABC transporter
GL185_RS03680	COG1744	ABC transporter substrate-binding protein PnrA-like
GL185_RS03685	COG0295	cytidine deaminase activity
GL185_RS03695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GL185_RS03700	COG2813	Specifically methylates the guanine in position
GL185_RS03740	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GL185_RS03760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GL185_RS03770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GL185_RS03775	COG1126	abc transporter atp-binding protein
GL185_RS03780	COG0765	amino acid transport
GL185_RS03785	COG4703	Protein of unknown function (DUF1797)
GL185_RS03790	COG0542	response to heat
GL185_RS03800	COG0494	nUDIX hydrolase
GL185_RS03820	COG0187	DNA topoisomerase II activity
GL185_RS03830	COG0693	protein deglycase activity
GL185_RS03835	COG0772	Belongs to the SEDS family
GL185_RS03855	COG5002	protein histidine kinase activity
GL185_RS03860	COG0745	RESPONSE REGULATOR receiver
GL185_RS03895	COG1028	Short-chain dehydrogenase reductase Sdr
GL185_RS03905	COG4989	oxidoreductase activity
GL185_RS03930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GL185_RS03930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GL185_RS03935	COG0577	efflux transmembrane transporter activity
GL185_RS03940	COG1136	(ABC) transporter
GL185_RS03945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GL185_RS03950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GL185_RS03960	COG0577	efflux transmembrane transporter activity
GL185_RS03960	COG1136	(ABC) transporter
GL185_RS03975	COG1268	BioY protein
GL185_RS03985	COG4443	Transcriptional Coactivator p15 (PC4)
GL185_RS03995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GL185_RS03995	COG1328	CTP reductase activity
GL185_RS04020	COG1837	Belongs to the UPF0109 family
GL185_RS04050	COG0488	(ABC) transporter
GL185_RS04060	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GL185_RS04065	COG4470	Protein conserved in bacteria
GL185_RS04070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GL185_RS04080	COG0167	dihydroorotate dehydrogenase activity
GL185_RS04090	COG0513	Belongs to the DEAD box helicase family
GL185_RS04100	COG2190	(PTS) system
GL185_RS04100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL185_RS04100	COG1263	PTS System
GL185_RS04110	COG2177	Part of the ABC transporter FtsEX involved in
GL185_RS04115	COG2884	Cell division ATP-binding protein ftsE
GL185_RS04125	COG0617	tRNA 3'-terminal CCA addition
GL185_RS04125	COG0517	IMP dehydrogenase activity
GL185_RS04125	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GL185_RS04165	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GL185_RS04170	COG2131	deaminase
GL185_RS04180	COG1307	EDD domain protein, DegV family
GL185_RS04185	COG2081	HI0933 family
GL185_RS04200	COG0733	neurotransmitter:sodium symporter activity
GL185_RS04205	COG1482	cell wall glycoprotein biosynthetic process
GL185_RS04210	COG2723	6-phospho-beta-galactosidase activity
GL185_RS04225	COG0028	Belongs to the TPP enzyme family
GL185_RS04230	COG2217	Heavy metal translocating P-type atpase
GL185_RS04250	COG0352	thiamine-phosphate diphosphorylase activity
GL185_RS04265	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GL185_RS04275	COG4172	Belongs to the ABC transporter superfamily
GL185_RS04285	COG0352	thiamine-phosphate diphosphorylase activity
GL185_RS04290	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GL185_RS04300	COG1304	FMN binding
GL185_RS04310	COG1304	FMN binding
GL185_RS04315	COG0765	amino acid transport
GL185_RS04320	COG0765	amino acid transport
GL185_RS04325	COG1126	abc transporter atp-binding protein
GL185_RS04335	COG1131	(ABC) transporter
GL185_RS04360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GL185_RS04370	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GL185_RS04385	COG1136	(ABC) transporter
GL185_RS04405	COG1217	gtp-binding protein TYPA
GL185_RS04410	COG1187	pseudouridine synthase activity
GL185_RS04420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GL185_RS04435	COG0300	oxidoreductase activity
GL185_RS04445	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GL185_RS04450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GL185_RS04470	COG1940	carbohydrate kinase activity
GL185_RS04485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GL185_RS04490	COG3064	Membrane
GL185_RS04500	COG2972	Histidine kinase
GL185_RS04505	COG2207	Transcriptional regulator
GL185_RS04505	COG4753	response regulator
GL185_RS04510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GL185_RS04510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GL185_RS04515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GL185_RS04520	COG0785	Cytochrome C biogenesis protein
GL185_RS04540	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GL185_RS04560	COG3250	beta-galactosidase activity
GL185_RS04565	COG3775	system Galactitol-specific IIC component
GL185_RS04580	COG1404	Belongs to the peptidase S8 family
GL185_RS04610	COG4555	ABC transporter
GL185_RS04650	COG1363	Peptidase, m42
GL185_RS04655	COG1114	Component of the transport system for branched-chain amino acids
GL185_RS04665	COG1573	uracil-dna glycosylase
GL185_RS04680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL185_RS04720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GL185_RS04720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GL185_RS04730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL185_RS04735	COG0765	amino acid transport
GL185_RS04740	COG0765	amino acid transport
GL185_RS04745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GL185_RS04750	COG0191	fructose-bisphosphate aldolase activity
GL185_RS04755	COG5002	protein histidine kinase activity
GL185_RS04760	COG0745	RESPONSE REGULATOR receiver
GL185_RS04765	COG0577	efflux transmembrane transporter activity
GL185_RS04770	COG1136	(ABC) transporter
GL185_RS04775	COG0577	efflux transmembrane transporter activity
GL185_RS04795	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GL185_RS04800	COG0215	cysteine-tRNA ligase activity
GL185_RS04810	COG1045	serine acetyltransferase
GL185_RS04825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GL185_RS04830	COG3620	sequence-specific DNA binding
GL185_RS04845	COG0072	phenylalanine-tRNA ligase activity
GL185_RS04845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GL185_RS04850	COG0456	acetyltransferase
GL185_RS04865	COG1263	PTS System
GL185_RS04865	COG2190	(PTS) system
GL185_RS04865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL185_RS04870	COG3711	transcriptional antiterminator
GL185_RS04895	COG0525	valine-tRNA ligase activity
GL185_RS04905	COG0519	Catalyzes the synthesis of GMP from XMP
GL185_RS04970	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GL185_RS04975	COG0195	Participates in both transcription termination and antitermination
GL185_RS04995	COG1266	CAAX protease self-immunity
GL185_RS05045	COG2274	protein secretion by the type I secretion system
GL185_RS05050	COG2274	protein secretion by the type I secretion system
GL185_RS05055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GL185_RS05075	COG1131	(ABC) transporter
GL185_RS05080	COG0537	adenosine 5'-monophosphoramidase activity
GL185_RS05095	COG0484	heat shock protein binding
GL185_RS05135	COG0732	type I restriction modification DNA specificity domain
GL185_RS05145	COG4974	Belongs to the 'phage' integrase family
GL185_RS05160	COG0174	glutamine synthetase
GL185_RS05165	COG0789	Transcriptional regulator
GL185_RS05185	COG1283	sodium-dependent phosphate transmembrane transporter activity
GL185_RS05190	COG0504	CTP synthase activity
GL185_RS05200	COG1247	-acetyltransferase
GL185_RS05210	COG0671	phosphoesterase, PA-phosphatase related
GL185_RS05215	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GL185_RS05230	COG1122	ATPase activity
GL185_RS05250	COG0569	domain protein
GL185_RS05255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GL185_RS05285	COG1882	Formate acetyltransferase
GL185_RS05290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GL185_RS05310	COG0765	amino acid transport
GL185_RS05325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GL185_RS05345	COG0440	acetolactate synthase activity
GL185_RS05350	COG0028	Belongs to the TPP enzyme family
GL185_RS05355	COG1461	Dihydroxyacetone kinase
GL185_RS05365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GL185_RS05375	COG1442	glycosyl transferase family 8
GL185_RS05380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GL185_RS05435	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GL185_RS05440	COG0439	Biotin carboxylase
GL185_RS05455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GL185_RS05460	COG1028	Short-chain dehydrogenase reductase Sdr
GL185_RS05465	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GL185_RS05475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GL185_RS05485	COG1846	Transcriptional regulator
GL185_RS05490	COG1024	Enoyl-CoA hydratase
GL185_RS05495	COG0527	aspartate kinase activity
GL185_RS05505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GL185_RS05520	COG1115	amino acid carrier protein
GL185_RS05545	COG0681	Belongs to the peptidase S26 family
GL185_RS05550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GL185_RS05565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL185_RS05570	COG3711	transcriptional antiterminator
GL185_RS05575	COG2213	PTS system mannitol-specific
GL185_RS05615	COG2197	response regulator
GL185_RS05620	COG4585	Histidine kinase
GL185_RS05675	COG0745	RESPONSE REGULATOR receiver
GL185_RS05680	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GL185_RS05690	COG0116	Belongs to the methyltransferase superfamily
GL185_RS05715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GL185_RS05720	COG0366	Alpha amylase catalytic
GL185_RS05725	COG4166	transmembrane transport
GL185_RS05740	COG1091	dTDP-4-dehydrorhamnose reductase activity
GL185_RS05745	COG1088	dTDP-glucose 4,6-dehydratase activity
GL185_RS05755	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GL185_RS05775	COG3475	LICD family
GL185_RS05785	COG1215	transferase activity, transferring glycosyl groups
GL185_RS05810	COG3475	LICD family
GL185_RS05835	COG4464	protein tyrosine phosphatase activity
GL185_RS05850	COG4166	transmembrane transport
GL185_RS05855	COG0366	Alpha amylase catalytic
GL185_RS05890	COG0768	penicillin binding
GL185_RS05895	COG4839	cell division protein FtsL
GL185_RS05925	COG1609	Transcriptional regulator
GL185_RS05940	COG3716	PTS system mannose fructose sorbose family IID component
GL185_RS05945	COG3715	PTS system
GL185_RS05950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL185_RS05955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GL185_RS05965	COG1028	Short-chain dehydrogenase reductase Sdr
GL185_RS05990	COG5492	domain, Protein
GL185_RS05995	COG0386	Belongs to the glutathione peroxidase family
GL185_RS06020	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GL185_RS06030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GL185_RS06030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GL185_RS06040	COG0285	dihydrofolate synthase activity
GL185_RS06045	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GL185_RS06055	COG2252	PERMEase
GL185_RS06065	COG1064	alcohol dehydrogenase
GL185_RS06075	COG3715	PTS system
GL185_RS06080	COG3716	PTS system mannose fructose sorbose family IID component
GL185_RS06085	COG3579	cysteine-type endopeptidase activity
GL185_RS06090	COG1187	pseudouridine synthase activity
GL185_RS06095	COG2261	transglycosylase associated protein
GL185_RS06100	COG2309	aminopeptidase activity
GL185_RS06120	COG2176	DNA-directed DNA polymerase activity
GL185_RS06140	COG1523	belongs to the glycosyl hydrolase 13 family
GL185_RS06150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GL185_RS06155	COG2723	6-phospho-beta-galactosidase activity
GL185_RS06165	COG0750	zinc metalloprotease
GL185_RS06170	COG4589	Belongs to the CDS family
GL185_RS06175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GL185_RS06220	COG1882	Formate acetyltransferase
GL185_RS06225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL185_RS06230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL185_RS06235	COG1447	Phosphotransferase system cellobiose-specific component IIA
GL185_RS06245	COG1349	DNA-binding transcription factor activity
GL185_RS06250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GL185_RS06270	COG3842	ATPase activity
GL185_RS06290	COG3830	Belongs to the UPF0237 family
GL185_RS06300	COG0202	RNA polymerase activity
GL185_RS06305	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GL185_RS06315	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GL185_RS06320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GL185_RS06330	COG0201	protein transport
GL185_RS06345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GL185_RS06385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GL185_RS06410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GL185_RS06470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GL185_RS06480	COG0285	dihydrofolate synthase activity
GL185_RS06505	COG1393	Belongs to the ArsC family
GL185_RS06510	COG0006	proline dipeptidase activity
GL185_RS06515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GL185_RS06540	COG0519	Catalyzes the synthesis of GMP from XMP
GL185_RS06560	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GL185_RS06560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GL185_RS06595	COG1780	Probably involved in ribonucleotide reductase function
GL185_RS06605	COG2207	Transcriptional regulator
GL185_RS06605	COG4753	response regulator
GL185_RS06610	COG2972	Histidine kinase
GL185_RS06630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GL185_RS06635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GL185_RS06640	COG1464	Belongs to the NlpA lipoprotein family
GL185_RS06645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL185_RS06685	COG1396	sequence-specific DNA binding
GL185_RS06750	COG1214	PFAM Peptidase M22, glycoprotease
GL185_RS06785	COG0445	tRNA wobble uridine modification
GL185_RS06790	COG0494	nUDIX hydrolase
GL185_RS06885	COG0137	argininosuccinate synthase activity
GL185_RS06890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL185_RS06915	COG1705	Flagellar rod assembly protein muramidase FlgJ
GL185_RS06915	COG1388	LysM domain
GL185_RS06920	COG1760	l-serine dehydratase
GL185_RS06925	COG1760	l-serine dehydratase
GL185_RS06930	COG0546	phosphoglycolate phosphatase activity
GL185_RS06955	COG1695	Transcriptional regulator
GL185_RS06985	COG1653	transport
GL185_RS06990	COG0395	ABC-type sugar transport system, permease component
GL185_RS06995	COG4209	transmembrane transport
GL185_RS07020	COG5002	protein histidine kinase activity
GL185_RS07045	COG0569	domain protein
GL185_RS07050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GL185_RS07080	COG1937	Protein conserved in bacteria
GL185_RS07085	COG2514	catechol 2,3-dioxygenase activity
GL185_RS07095	COG2222	sugar isomerase
GL185_RS07105	COG3716	PTS system mannose fructose sorbose family IID component
GL185_RS07110	COG3715	PTS system
GL185_RS07115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL185_RS07130	COG3064	Membrane
GL185_RS07130	COG3583	domain protein
GL185_RS07130	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GL185_RS07135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GL185_RS07150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GL185_RS07155	COG0151	Belongs to the GarS family
GL185_RS07170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GL185_RS07185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GL185_RS07195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GL185_RS07200	COG2274	protein secretion by the type I secretion system
GL185_RS07210	COG1388	LysM domain
GL185_RS07210	COG1134	teichoic acid transport
GL185_RS07245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GL185_RS07260	COG0436	Aminotransferase
GL185_RS07265	COG2855	membrane
GL185_RS07275	COG1832	CoA-binding protein
GL185_RS07280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GL185_RS07280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GL185_RS07305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GL185_RS07325	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GL185_RS07335	COG0756	dUTP diphosphatase activity
GL185_RS07465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GL185_RS07470	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GL185_RS07490	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GL185_RS07495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GL185_RS07505	COG0012	GTP binding
GL185_RS07515	COG0592	DNA-directed DNA polymerase activity
GL185_RS07525	COG1475	DNA binding
GL185_RS07530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GL185_RS07575	COG1511	domain protein
GL185_RS07585	COG1511	domain protein
GL185_RS07595	COG0488	(ABC) transporter
GL185_RS07600	COG0180	Tryptophanyl-tRNA synthetase
GL185_RS07605	COG0517	IMP dehydrogenase activity
GL185_RS07605	COG0516	GMP reductase activity
GL185_RS07615	COG2501	S4 domain
GL185_RS07620	COG0612	Peptidase, M16
GL185_RS07625	COG0612	Peptidase, M16
GL185_RS07635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GL185_RS07640	COG1122	ATPase activity
GL185_RS07645	COG1122	ATPase activity
GL185_RS07650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GL185_RS07655	COG1792	Involved in formation and maintenance of cell shape
GL185_RS07665	COG3942	CHAP domain
GL185_RS07700	COG1739	Uncharacterized protein family UPF0029
GL185_RS07705	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GL185_RS07710	COG1040	competence protein
GL185_RS07730	COG0305	Participates in initiation and elongation during chromosome replication
GL185_RS07750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GL185_RS07755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GL185_RS07760	COG1116	anion transmembrane transporter activity
GL185_RS07765	COG4463	regulation of RNA biosynthetic process
GL185_RS07770	COG0542	response to heat
GL185_RS07775	COG0745	RESPONSE REGULATOR receiver
GL185_RS07780	COG5002	protein histidine kinase activity
GL185_RS07785	COG1755	Isoprenylcysteine carboxyl methyltransferase
GL185_RS07795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GL185_RS07815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GL185_RS07820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GL185_RS07840	COG2211	Major facilitator Superfamily
GL185_RS07855	COG1696	Membrane protein involved in D-alanine export
GL185_RS07865	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GL185_RS07870	COG1846	Transcriptional regulator
GL185_RS07875	COG1121	(ABC) transporter
GL185_RS07880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GL185_RS07885	COG0803	Belongs to the bacterial solute-binding protein 9 family
GL185_RS07885	COG3443	Belongs to the bacterial solute-binding protein 9 family
GL185_RS07895	COG1070	Carbohydrate kinase
GL185_RS07915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL185_RS07925	COG3716	PTS system mannose fructose sorbose family IID component
GL185_RS07945	COG1454	alcohol dehydrogenase
GL185_RS07970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GL185_RS07975	COG1288	antiporter activity
GL185_RS07980	COG0549	Belongs to the carbamate kinase family
GL185_RS08000	COG3537	Alpha-1,2-mannosidase
GL185_RS08010	COG0383	alpha-mannosidase activity
GL185_RS08045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GL185_RS08065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL185_RS08080	COG3959	Transketolase, thiamine diphosphate binding domain
GL185_RS08085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GL185_RS08100	COG2151	metal-sulfur cluster biosynthetic enzyme
GL185_RS08130	COG1476	TRANSCRIPTIONal
GL185_RS08170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GL185_RS08180	COG1609	Transcriptional regulator
GL185_RS08185	COG5521	maltodextrose utilization protein MalA
GL185_RS08190	COG3833	ABC-type maltose transport systems, permease component
GL185_RS08195	COG1175	transmembrane transport
GL185_RS08200	COG2182	Extracellular solute-binding protein
GL185_RS08205	COG1640	4-alpha-glucanotransferase
GL185_RS08210	COG0058	SHG alpha-glucan phosphorylase activity
GL185_RS08220	COG2226	methyltransferase
GL185_RS08230	COG2217	Heavy metal translocating P-type atpase
GL185_RS08240	COG4499	WXG100 protein secretion system (Wss), protein YukC
GL185_RS08240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GL185_RS08245	COG0697	spore germination
GL185_RS08260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GL185_RS08270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GL185_RS08290	COG0704	Plays a role in the regulation of phosphate uptake
GL185_RS08295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GL185_RS08305	COG0573	inorganic phosphate transmembrane transporter activity
GL185_RS08310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GL185_RS08315	COG5002	protein histidine kinase activity
GL185_RS08320	COG0745	RESPONSE REGULATOR receiver
GL185_RS08345	COG1438	arginine binding
GL185_RS08355	COG1132	(ABC) transporter
GL185_RS08365	COG1132	(ABC) transporter
GL185_RS08370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GL185_RS08485	COG0534	Mate efflux family protein
GL185_RS08490	COG0131	Imidazoleglycerol-phosphate dehydratase
GL185_RS08490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GL185_RS08505	COG3759	membrane
GL185_RS08510	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GL185_RS08535	COG1063	alcohol dehydrogenase
GL185_RS08545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GL185_RS08550	COG1459	type II secretion system
GL185_RS08555	COG4537	Required for transformation and DNA binding
GL185_RS08580	COG2226	methyltransferase
GL185_RS08600	COG0706	membrane insertase activity
GL185_RS08605	COG1847	R3H domain protein
GL185_RS08615	COG3037	sugar-specific permease SgaT UlaA
GL185_RS08625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL185_RS08635	COG3623	hexulose-6-phosphate isomerase
GL185_RS08655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GL185_RS08665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GL185_RS08675	COG1012	belongs to the aldehyde dehydrogenase family
GL185_RS08675	COG1454	alcohol dehydrogenase
GL185_RS08680	COG1447	Phosphotransferase system cellobiose-specific component IIA
GL185_RS08690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL185_RS08695	COG2723	6-phospho-beta-galactosidase activity
GL185_RS08700	COG2188	Transcriptional regulator
GL185_RS08705	COG1129	ABC transporter
GL185_RS08715	COG0157	Belongs to the NadC ModD family
GL185_RS08725	COG0577	efflux transmembrane transporter activity
GL185_RS08735	COG0564	pseudouridine synthase activity
GL185_RS08740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GL185_RS08745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GL185_RS08845	COG1131	(ABC) transporter
GL185_RS08850	COG0842	Transport permease protein
GL185_RS08855	COG4585	Histidine kinase
GL185_RS08860	COG2197	response regulator
GL185_RS08865	COG1609	Transcriptional regulator
GL185_RS08870	COG0252	asparaginase activity
GL185_RS08875	COG0561	phosphatase activity
GL185_RS08880	COG0589	response to stress
GL185_RS08890	COG0436	Aminotransferase
GL185_RS08910	COG0084	hydrolase, TatD family'
GL185_RS08915	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GL185_RS08950	COG1162	GTPase activity
GL185_RS08960	COG1564	THIamine pyrophosphokinase
GL185_RS08975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GL185_RS08985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GL185_RS08995	COG1254	Belongs to the acylphosphatase family
GL185_RS09000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GL185_RS09015	COG0742	ribosomal rna small subunit methyltransferase
GL185_RS09025	COG3480	Lon protease (S16) C-terminal proteolytic domain
GL185_RS09035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GL185_RS09050	COG1253	flavin adenine dinucleotide binding
GL185_RS09075	COG0577	efflux transmembrane transporter activity
GL185_RS09075	COG1136	(ABC) transporter
GL185_RS09100	COG0802	atpase or kinase
GL185_RS09110	COG1316	TRANSCRIPTIONal
GL185_RS09130	COG5632	N-Acetylmuramoyl-L-alanine amidase
GL185_RS09130	COG5263	repeat protein
GL185_RS09215	COG1132	(ABC) transporter
GL185_RS09220	COG2274	protein secretion by the type I secretion system
GL185_RS09260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GL185_RS09265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GL185_RS09270	COG4221	oxidoreductase activity
GL185_RS09310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GL185_RS09430	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GL185_RS09430	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GL185_RS09435	COG2207	Transcriptional regulator
GL185_RS09440	COG3345	alpha-galactosidase
GL185_RS09445	COG1653	transport
GL185_RS09450	COG1175	transmembrane transport
GL185_RS09455	COG0395	ABC-type sugar transport system, permease component
GL185_RS09465	COG0366	Alpha amylase catalytic
GL185_RS09480	COG4166	transmembrane transport
GL185_RS09485	COG0601	transmembrane transport
GL185_RS09490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GL185_RS09495	COG0444	Belongs to the ABC transporter superfamily
GL185_RS09500	COG4608	Belongs to the ABC transporter superfamily
GL185_RS09510	COG4120	Belongs to the binding-protein-dependent transport system permease family
GL185_RS09515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GL185_RS09520	COG2188	Transcriptional regulator
GL185_RS09525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL185_RS09525	COG1263	PTS System
GL185_RS09530	COG0366	Alpha amylase catalytic
GL185_RS09545	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GL185_RS09555	COG0517	IMP dehydrogenase activity
GL185_RS09575	COG1187	pseudouridine synthase activity
GL185_RS09585	COG4607	ABC-type enterochelin transport system periplasmic component
GL185_RS09590	COG4604	ABC transporter, ATP-binding protein
GL185_RS09595	COG4605	iron ion homeostasis
GL185_RS09600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GL185_RS09610	COG1363	Peptidase, m42
GL185_RS09630	COG0517	IMP dehydrogenase activity
GL185_RS09630	COG1125	glycine betaine transport
GL185_RS09635	COG1174	glycine betaine transport
GL185_RS09640	COG3201	nicotinamide mononucleotide transporter
GL185_RS09650	COG1230	cation diffusion facilitator family transporter
GL185_RS09655	COG0789	Transcriptional regulator
GL185_RS09660	COG1063	alcohol dehydrogenase
GL185_RS09665	COG1609	Transcriptional regulator
GL185_RS09670	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GL185_RS09695	COG2233	PERMEase
GL185_RS09715	COG0708	Exodeoxyribonuclease III
GL185_RS09730	COG1132	(ABC) transporter
GL185_RS09735	COG1132	(ABC) transporter
GL185_RS09740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GL185_RS09745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GL185_RS09750	COG5434	Belongs to the glycosyl hydrolase 28 family
GL185_RS09775	COG1178	ABC-type Fe3 transport system permease component
GL185_RS09780	COG1285	pathogenesis
GL185_RS09805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GL185_RS09810	COG0512	Glutamine amidotransferase of anthranilate synthase
GL185_RS09825	COG0135	phosphoribosylanthranilate isomerase activity
GL185_RS09865	COG1846	Transcriptional regulator
GL185_RS09865	COG1940	carbohydrate kinase activity
GL185_RS09870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL185_RS09880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL185_RS09885	COG1447	Phosphotransferase system cellobiose-specific component IIA
GL185_RS09890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL185_RS09900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GL185_RS09920	COG3237	CsbD-like
GL185_RS09940	COG2261	transglycosylase associated protein
GL185_RS09945	COG3711	transcriptional antiterminator
GL185_RS09955	COG4209	transmembrane transport
GL185_RS09960	COG0395	ABC-type sugar transport system, permease component
GL185_RS09965	COG1653	transport
GL185_RS09970	COG1621	beta-fructofuranosidase activity
GL185_RS09980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GL185_RS10015	COG1051	belongs to the nudix hydrolase family
GL185_RS10030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GL185_RS10035	COG1164	Oligoendopeptidase f
GL185_RS10040	COG0640	Transcriptional regulator
GL185_RS10045	COG1131	(ABC) transporter
GL185_RS10060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GL185_RS10070	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GL185_RS10075	COG3118	belongs to the thioredoxin family
GL185_RS10100	COG0668	transmembrane transport
GL185_RS10115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GL185_RS10120	COG1534	Rna-binding protein
GL185_RS10125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GL185_RS10130	COG1713	HD superfamily hydrolase involved in NAD metabolism
GL185_RS10140	COG0799	negative regulation of ribosome biogenesis
GL185_RS10145	COG2226	methyltransferase
GL185_RS10165	COG0194	GDP metabolic process
GL185_RS10175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GL185_RS10185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GL185_RS10185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GL185_RS10190	COG0631	protein serine/threonine phosphatase activity
GL185_RS10195	COG2815	serine threonine protein kinase
GL185_RS10195	COG0515	serine threonine protein kinase
GL185_RS10220	COG3425	synthase
GL185_RS10230	COG1609	Transcriptional regulator
GL185_RS10235	COG1621	beta-fructofuranosidase activity
GL185_RS10240	COG2190	(PTS) system
GL185_RS10240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL185_RS10240	COG1263	PTS System
GL185_RS10245	COG1940	carbohydrate kinase activity
GL185_RS10265	COG4152	abc transporter atp-binding protein
GL185_RS10270	COG1668	transmembrane transport
GL185_RS10280	COG1131	(ABC) transporter
GL185_RS10285	COG1725	Transcriptional regulator
GL185_RS10300	COG1484	DNA-dependent DNA replication
GL185_RS10305	COG0778	Nitroreductase
GL185_RS10345	COG1131	(ABC) transporter
GL185_RS10355	COG0653	protein targeting
GL185_RS10360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GL185_RS10365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GL185_RS10380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GL185_RS10390	COG3458	cephalosporin-C deacetylase activity
GL185_RS10415	COG1653	transport
GL185_RS10420	COG1175	transmembrane transport
GL185_RS10430	COG4409	exo-alpha-(2->6)-sialidase activity
GL185_RS10435	COG0673	inositol 2-dehydrogenase activity
GL185_RS10445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL185_RS10445	COG1263	PTS System
GL185_RS10445	COG2190	(PTS) system
GL185_RS10455	COG1175	transmembrane transport
GL185_RS10460	COG0395	ABC-type sugar transport system, permease component
GL185_RS10465	COG2731	YhcH YjgK YiaL family protein
GL185_RS10480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GL185_RS10495	COG0768	penicillin binding
GL185_RS10510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GL185_RS10515	COG1051	belongs to the nudix hydrolase family
GL185_RS10535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GL185_RS10555	COG3599	regulation of cell shape
GL185_RS10585	COG1136	(ABC) transporter
GL185_RS10585	COG0577	efflux transmembrane transporter activity
GL185_RS10595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GL185_RS10600	COG0803	Belongs to the bacterial solute-binding protein 9 family
GL185_RS10615	COG3590	peptidase
GL185_RS10660	COG1959	2 iron, 2 sulfur cluster binding
GL185_RS10675	COG0745	RESPONSE REGULATOR receiver
GL185_RS10680	COG5002	protein histidine kinase activity
GL185_RS10700	COG2910	NAD(P)H-binding
GL185_RS10715	COG0204	Acyl-transferase
GL185_RS10720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GL185_RS10725	COG2384	SAM-dependent methyltransferase
GL185_RS10730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GL185_RS10735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GL185_RS10745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GL185_RS10750	COG0463	Glycosyl transferase, family 2
GL185_RS10770	COG2824	Alkylphosphonate utilization operon protein PhnA
GL185_RS10790	COG0351	phosphomethylpyrimidine kinase
GL185_RS10795	COG4720	Psort location CytoplasmicMembrane, score
GL185_RS10800	COG0006	proline dipeptidase activity
GL185_RS10805	COG3442	glutamine amidotransferase
GL185_RS10810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GL185_RS10815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GL185_RS10820	COG2223	nitrite transmembrane transporter activity
GL185_RS10825	COG0513	Belongs to the DEAD box helicase family
GL185_RS10835	COG1335	isochorismatase
GL185_RS10845	COG3842	ATPase activity
GL185_RS10855	COG2226	methyltransferase
GL185_RS10870	COG3935	DnaD domain protein
GL185_RS10880	COG5263	repeat protein
GL185_RS10880	COG4193	domain, Protein
GL185_RS10890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GL185_RS10910	COG0251	oxidation-reduction process