locus-tag	class	description
GL186_RS00005	COG0592	DNA-directed DNA polymerase activity
GL186_RS00015	COG0012	GTP binding
GL186_RS00025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GL186_RS00030	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GL186_RS00050	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GL186_RS00055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GL186_RS00185	COG0756	dUTP diphosphatase activity
GL186_RS00195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GL186_RS00210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GL186_RS00235	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GL186_RS00235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GL186_RS00240	COG1832	CoA-binding protein
GL186_RS00250	COG2855	membrane
GL186_RS00255	COG0436	Aminotransferase
GL186_RS00270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GL186_RS00305	COG1388	LysM domain
GL186_RS00305	COG1134	teichoic acid transport
GL186_RS00315	COG2274	protein secretion by the type I secretion system
GL186_RS00320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GL186_RS00330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GL186_RS00345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GL186_RS00360	COG0151	Belongs to the GarS family
GL186_RS00365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GL186_RS00380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GL186_RS00385	COG3583	domain protein
GL186_RS00385	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GL186_RS00385	COG3064	Membrane
GL186_RS00400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL186_RS00405	COG3715	PTS system
GL186_RS00410	COG3716	PTS system mannose fructose sorbose family IID component
GL186_RS00420	COG2222	sugar isomerase
GL186_RS00430	COG2514	catechol 2,3-dioxygenase activity
GL186_RS00435	COG1937	Protein conserved in bacteria
GL186_RS00465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GL186_RS00470	COG0569	domain protein
GL186_RS00495	COG5002	protein histidine kinase activity
GL186_RS00520	COG4209	transmembrane transport
GL186_RS00525	COG0395	ABC-type sugar transport system, permease component
GL186_RS00530	COG1653	transport
GL186_RS00560	COG1695	Transcriptional regulator
GL186_RS00585	COG0546	phosphoglycolate phosphatase activity
GL186_RS00590	COG1760	l-serine dehydratase
GL186_RS00595	COG1760	l-serine dehydratase
GL186_RS00680	COG0494	nUDIX hydrolase
GL186_RS00685	COG0445	tRNA wobble uridine modification
GL186_RS00720	COG1214	PFAM Peptidase M22, glycoprotease
GL186_RS00785	COG1396	sequence-specific DNA binding
GL186_RS00825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL186_RS00830	COG1464	Belongs to the NlpA lipoprotein family
GL186_RS00835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GL186_RS00840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GL186_RS00860	COG2972	Histidine kinase
GL186_RS00865	COG4753	response regulator
GL186_RS00865	COG2207	Transcriptional regulator
GL186_RS00875	COG1780	Probably involved in ribonucleotide reductase function
GL186_RS00905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GL186_RS00905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GL186_RS00925	COG2818	Glycosylase
GL186_RS00950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GL186_RS00955	COG0006	proline dipeptidase activity
GL186_RS00960	COG1393	Belongs to the ArsC family
GL186_RS00985	COG0285	dihydrofolate synthase activity
GL186_RS00995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GL186_RS01060	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GL186_RS01085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GL186_RS01125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GL186_RS01140	COG0201	protein transport
GL186_RS01150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GL186_RS01155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GL186_RS01165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GL186_RS01170	COG0202	RNA polymerase activity
GL186_RS01180	COG3830	Belongs to the UPF0237 family
GL186_RS01200	COG3842	ATPase activity
GL186_RS01215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GL186_RS01220	COG1349	DNA-binding transcription factor activity
GL186_RS01230	COG1447	Phosphotransferase system cellobiose-specific component IIA
GL186_RS01235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL186_RS01240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL186_RS01245	COG1882	Formate acetyltransferase
GL186_RS01290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GL186_RS01295	COG4589	Belongs to the CDS family
GL186_RS01300	COG0750	zinc metalloprotease
GL186_RS01310	COG2723	6-phospho-beta-galactosidase activity
GL186_RS01315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GL186_RS01325	COG1523	belongs to the glycosyl hydrolase 13 family
GL186_RS01345	COG2176	DNA-directed DNA polymerase activity
GL186_RS01365	COG2309	aminopeptidase activity
GL186_RS01370	COG2261	transglycosylase associated protein
GL186_RS01375	COG1187	pseudouridine synthase activity
GL186_RS01380	COG3579	cysteine-type endopeptidase activity
GL186_RS01385	COG3716	PTS system mannose fructose sorbose family IID component
GL186_RS01390	COG3715	PTS system
GL186_RS01400	COG1064	alcohol dehydrogenase
GL186_RS01405	COG0561	phosphatase activity
GL186_RS01410	COG2252	PERMEase
GL186_RS01420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GL186_RS01425	COG0285	dihydrofolate synthase activity
GL186_RS01435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GL186_RS01435	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GL186_RS01445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GL186_RS01470	COG0386	Belongs to the glutathione peroxidase family
GL186_RS01475	COG5492	domain, Protein
GL186_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
GL186_RS01510	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GL186_RS01515	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL186_RS01520	COG3715	PTS system
GL186_RS01525	COG3716	PTS system mannose fructose sorbose family IID component
GL186_RS01540	COG1609	Transcriptional regulator
GL186_RS01565	COG4839	cell division protein FtsL
GL186_RS01570	COG0768	penicillin binding
GL186_RS01600	COG0366	Alpha amylase catalytic
GL186_RS01605	COG4166	transmembrane transport
GL186_RS01620	COG4464	protein tyrosine phosphatase activity
GL186_RS01645	COG3475	LICD family
GL186_RS01670	COG1215	transferase activity, transferring glycosyl groups
GL186_RS01680	COG3475	LICD family
GL186_RS01700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GL186_RS01710	COG1088	dTDP-glucose 4,6-dehydratase activity
GL186_RS01715	COG1091	dTDP-4-dehydrorhamnose reductase activity
GL186_RS01725	COG4166	transmembrane transport
GL186_RS01730	COG0366	Alpha amylase catalytic
GL186_RS01735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GL186_RS01760	COG0116	Belongs to the methyltransferase superfamily
GL186_RS01770	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GL186_RS01775	COG0745	RESPONSE REGULATOR receiver
GL186_RS01830	COG4585	Histidine kinase
GL186_RS01835	COG2197	response regulator
GL186_RS01875	COG2213	PTS system mannitol-specific
GL186_RS01880	COG3711	transcriptional antiterminator
GL186_RS01885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL186_RS01900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GL186_RS01905	COG0681	Belongs to the peptidase S26 family
GL186_RS01930	COG1115	amino acid carrier protein
GL186_RS01945	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GL186_RS01955	COG0527	aspartate kinase activity
GL186_RS01960	COG1024	Enoyl-CoA hydratase
GL186_RS01965	COG1846	Transcriptional regulator
GL186_RS01975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GL186_RS01985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GL186_RS01990	COG1028	Short-chain dehydrogenase reductase Sdr
GL186_RS01995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GL186_RS02010	COG0439	Biotin carboxylase
GL186_RS02015	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GL186_RS02070	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GL186_RS02075	COG1442	glycosyl transferase family 8
GL186_RS02085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GL186_RS02095	COG1461	Dihydroxyacetone kinase
GL186_RS02100	COG0028	Belongs to the TPP enzyme family
GL186_RS02105	COG0440	acetolactate synthase activity
GL186_RS02125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GL186_RS02140	COG0765	amino acid transport
GL186_RS02160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GL186_RS02165	COG1882	Formate acetyltransferase
GL186_RS02195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GL186_RS02200	COG0569	domain protein
GL186_RS02220	COG1122	ATPase activity
GL186_RS02235	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GL186_RS02240	COG0671	phosphoesterase, PA-phosphatase related
GL186_RS02250	COG1247	-acetyltransferase
GL186_RS02260	COG0504	CTP synthase activity
GL186_RS02265	COG1283	sodium-dependent phosphate transmembrane transporter activity
GL186_RS02285	COG0789	Transcriptional regulator
GL186_RS02290	COG0174	glutamine synthetase
GL186_RS02305	COG4974	Belongs to the 'phage' integrase family
GL186_RS02350	COG0484	heat shock protein binding
GL186_RS02365	COG0537	adenosine 5'-monophosphoramidase activity
GL186_RS02370	COG1131	(ABC) transporter
GL186_RS02395	COG3290	protein histidine kinase activity
GL186_RS02405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GL186_RS02410	COG2274	protein secretion by the type I secretion system
GL186_RS02415	COG2274	protein secretion by the type I secretion system
GL186_RS02465	COG1266	CAAX protease self-immunity
GL186_RS02485	COG0195	Participates in both transcription termination and antitermination
GL186_RS02490	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GL186_RS02555	COG0519	Catalyzes the synthesis of GMP from XMP
GL186_RS02565	COG0525	valine-tRNA ligase activity
GL186_RS02590	COG3711	transcriptional antiterminator
GL186_RS02595	COG2190	(PTS) system
GL186_RS02595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL186_RS02595	COG1263	PTS System
GL186_RS02610	COG0456	acetyltransferase
GL186_RS02615	COG0072	phenylalanine-tRNA ligase activity
GL186_RS02615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GL186_RS02630	COG3620	sequence-specific DNA binding
GL186_RS02635	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GL186_RS02650	COG1045	serine acetyltransferase
GL186_RS02660	COG0215	cysteine-tRNA ligase activity
GL186_RS02665	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GL186_RS02690	COG0577	efflux transmembrane transporter activity
GL186_RS02695	COG1136	(ABC) transporter
GL186_RS02700	COG0577	efflux transmembrane transporter activity
GL186_RS02705	COG0745	RESPONSE REGULATOR receiver
GL186_RS02710	COG5002	protein histidine kinase activity
GL186_RS02715	COG0191	fructose-bisphosphate aldolase activity
GL186_RS02720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GL186_RS02725	COG0765	amino acid transport
GL186_RS02730	COG0765	amino acid transport
GL186_RS02735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL186_RS02745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GL186_RS02745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GL186_RS02785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL186_RS02800	COG1573	uracil-dna glycosylase
GL186_RS02815	COG1114	Component of the transport system for branched-chain amino acids
GL186_RS02820	COG1363	Peptidase, m42
GL186_RS02855	COG4555	ABC transporter
GL186_RS02885	COG1404	Belongs to the peptidase S8 family
GL186_RS02905	COG3775	system Galactitol-specific IIC component
GL186_RS02910	COG3250	beta-galactosidase activity
GL186_RS02930	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GL186_RS02950	COG0785	Cytochrome C biogenesis protein
GL186_RS02955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GL186_RS02960	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GL186_RS02960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GL186_RS02965	COG2207	Transcriptional regulator
GL186_RS02965	COG4753	response regulator
GL186_RS02970	COG2972	Histidine kinase
GL186_RS02980	COG3064	Membrane
GL186_RS02985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GL186_RS03000	COG1940	carbohydrate kinase activity
GL186_RS03020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GL186_RS03025	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GL186_RS03035	COG0300	oxidoreductase activity
GL186_RS03050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GL186_RS03060	COG1187	pseudouridine synthase activity
GL186_RS03065	COG1217	gtp-binding protein TYPA
GL186_RS03085	COG1136	(ABC) transporter
GL186_RS03100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GL186_RS03110	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GL186_RS03135	COG1131	(ABC) transporter
GL186_RS03145	COG1126	abc transporter atp-binding protein
GL186_RS03150	COG0765	amino acid transport
GL186_RS03155	COG0765	amino acid transport
GL186_RS03160	COG1304	FMN binding
GL186_RS03170	COG1304	FMN binding
GL186_RS03180	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GL186_RS03185	COG0352	thiamine-phosphate diphosphorylase activity
GL186_RS03195	COG4172	Belongs to the ABC transporter superfamily
GL186_RS03205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GL186_RS03220	COG0352	thiamine-phosphate diphosphorylase activity
GL186_RS03240	COG2217	Heavy metal translocating P-type atpase
GL186_RS03245	COG0028	Belongs to the TPP enzyme family
GL186_RS03260	COG2723	6-phospho-beta-galactosidase activity
GL186_RS03265	COG1482	cell wall glycoprotein biosynthetic process
GL186_RS03270	COG0733	neurotransmitter:sodium symporter activity
GL186_RS03275	COG0789	Transcriptional regulator
GL186_RS03290	COG2081	HI0933 family
GL186_RS03295	COG1307	EDD domain protein, DegV family
GL186_RS03305	COG2131	deaminase
GL186_RS03310	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GL186_RS03350	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GL186_RS03350	COG0617	tRNA 3'-terminal CCA addition
GL186_RS03350	COG0517	IMP dehydrogenase activity
GL186_RS03360	COG2884	Cell division ATP-binding protein ftsE
GL186_RS03365	COG2177	Part of the ABC transporter FtsEX involved in
GL186_RS03375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL186_RS03375	COG1263	PTS System
GL186_RS03375	COG2190	(PTS) system
GL186_RS03385	COG0513	Belongs to the DEAD box helicase family
GL186_RS03395	COG0167	dihydroorotate dehydrogenase activity
GL186_RS03405	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GL186_RS03410	COG4470	Protein conserved in bacteria
GL186_RS03415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GL186_RS03425	COG0488	(ABC) transporter
GL186_RS03455	COG1837	Belongs to the UPF0109 family
GL186_RS03480	COG1328	CTP reductase activity
GL186_RS03480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GL186_RS03490	COG4443	Transcriptional Coactivator p15 (PC4)
GL186_RS03500	COG1268	BioY protein
GL186_RS03515	COG1136	(ABC) transporter
GL186_RS03515	COG0577	efflux transmembrane transporter activity
GL186_RS03525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GL186_RS03530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GL186_RS03535	COG1136	(ABC) transporter
GL186_RS03540	COG0577	efflux transmembrane transporter activity
GL186_RS03545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GL186_RS03545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GL186_RS03570	COG4989	oxidoreductase activity
GL186_RS03580	COG1028	Short-chain dehydrogenase reductase Sdr
GL186_RS03615	COG0745	RESPONSE REGULATOR receiver
GL186_RS03620	COG5002	protein histidine kinase activity
GL186_RS03640	COG0772	Belongs to the SEDS family
GL186_RS03645	COG0693	protein deglycase activity
GL186_RS03655	COG0187	DNA topoisomerase II activity
GL186_RS03675	COG0494	nUDIX hydrolase
GL186_RS03685	COG0542	response to heat
GL186_RS03690	COG4703	Protein of unknown function (DUF1797)
GL186_RS03695	COG0765	amino acid transport
GL186_RS03700	COG1126	abc transporter atp-binding protein
GL186_RS03705	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GL186_RS03715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GL186_RS03735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GL186_RS03780	COG2813	Specifically methylates the guanine in position
GL186_RS03785	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GL186_RS03795	COG0295	cytidine deaminase activity
GL186_RS03800	COG1744	ABC transporter substrate-binding protein PnrA-like
GL186_RS03805	COG3845	ABC transporter
GL186_RS03810	COG4603	Belongs to the binding-protein-dependent transport system permease family
GL186_RS03815	COG1079	Belongs to the binding-protein-dependent transport system permease family
GL186_RS03830	COG0187	DNA topoisomerase II activity
GL186_RS03835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GL186_RS03840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GL186_RS03845	COG4166	transmembrane transport
GL186_RS03880	COG0539	negative regulation of cytoplasmic translation
GL186_RS03890	COG1956	GAF domain-containing protein
GL186_RS03895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GL186_RS03910	COG0719	Fe-S assembly protein
GL186_RS03915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GL186_RS03925	COG0719	Fe-S assembly protein
GL186_RS03930	COG1686	Belongs to the peptidase S11 family
GL186_RS03935	COG0628	permease
GL186_RS03950	COG1349	DNA-binding transcription factor activity
GL186_RS03955	COG1105	Belongs to the carbohydrate kinase PfkB family
GL186_RS03960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GL186_RS03960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GL186_RS03960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL186_RS03965	COG1674	ftsk spoiiie
GL186_RS03965	COG0697	spore germination
GL186_RS03975	COG1104	cysteine desulfurase activity
GL186_RS04025	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GL186_RS04035	COG1438	arginine binding
GL186_RS04055	COG0469	pyruvate kinase activity
GL186_RS04085	COG3689	TIGRFAM TIGR03943 family protein
GL186_RS04090	COG0701	Predicted permease
GL186_RS04100	COG2183	response to ionizing radiation
GL186_RS04125	COG1136	(ABC) transporter
GL186_RS04130	COG0577	efflux transmembrane transporter activity
GL186_RS04145	COG1982	Orn Lys Arg decarboxylase major
GL186_RS04155	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GL186_RS04175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GL186_RS04180	COG0561	phosphatase activity
GL186_RS04200	COG0583	DNA-binding transcription factor activity
GL186_RS04205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GL186_RS04210	COG0564	pseudouridine synthase activity
GL186_RS04215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GL186_RS04230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GL186_RS04240	COG0470	DNA polymerase III
GL186_RS04285	COG0528	UMP kinase activity
GL186_RS04295	COG2996	Protein conserved in bacteria
GL186_RS04305	COG1702	phosphate starvation-inducible protein PhoH
GL186_RS04325	COG0686	Belongs to the AlaDH PNT family
GL186_RS04330	COG0686	Belongs to the AlaDH PNT family
GL186_RS04335	COG0686	Belongs to the AlaDH PNT family
GL186_RS04340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GL186_RS04345	COG1555	photosystem II stabilization
GL186_RS04345	COG1596	polysaccharide export
GL186_RS04350	COG0658	competence protein
GL186_RS04350	COG2333	competence protein COMEC
GL186_RS04360	COG1131	(ABC) transporter
GL186_RS04390	COG0543	2 iron, 2 sulfur cluster binding
GL186_RS04395	COG0167	dihydroorotate dehydrogenase activity
GL186_RS04400	COG4193	domain, Protein
GL186_RS04400	COG5263	repeat protein
GL186_RS04405	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GL186_RS04415	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GL186_RS04425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GL186_RS04430	COG0237	dephospho-CoA kinase activity
GL186_RS04435	COG2814	Major facilitator Superfamily
GL186_RS04440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GL186_RS04450	COG0557	exoribonuclease II activity
GL186_RS04460	COG3615	Tellurite resistance protein tehB
GL186_RS04460	COG0500	methyltransferase
GL186_RS04475	COG4122	O-methyltransferase activity
GL186_RS04500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GL186_RS04515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GL186_RS04520	COG0494	nUDIX hydrolase
GL186_RS04530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GL186_RS04540	COG2176	DNA-directed DNA polymerase activity
GL186_RS04545	COG0584	glycerophosphoryl diester phosphodiesterase
GL186_RS04565	COG0785	Cytochrome C biogenesis protein
GL186_RS04570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GL186_RS04575	COG0531	amino acid
GL186_RS04580	COG3443	Belongs to the bacterial solute-binding protein 9 family
GL186_RS04580	COG0803	Belongs to the bacterial solute-binding protein 9 family
GL186_RS04630	COG1970	mechanosensitive ion channel activity
GL186_RS04640	COG4708	membrane
GL186_RS04650	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GL186_RS04660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GL186_RS04665	COG1942	4-Oxalocrotonate Tautomerase
GL186_RS04670	COG1435	thymidine kinase activity
GL186_RS04680	COG2890	protein-(glutamine-N5) methyltransferase activity
GL186_RS04705	COG0741	lytic transglycosylase activity
GL186_RS04715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GL186_RS04730	COG0270	DNA (cytosine-5-)-methyltransferase activity
GL186_RS04785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GL186_RS04800	COG0791	NLP P60 protein
GL186_RS04800	COG0741	lytic transglycosylase activity
GL186_RS04845	COG2946	Replication initiation factor
GL186_RS04855	COG1674	ftsk spoiiie
GL186_RS04925	COG1396	sequence-specific DNA binding
GL186_RS04930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GL186_RS04940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GL186_RS05025	COG1396	sequence-specific DNA binding
GL186_RS05030	COG0542	response to heat
GL186_RS05060	COG3843	relaxase mobilization nuclease domain protein
GL186_RS05080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GL186_RS05100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GL186_RS05105	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GL186_RS05155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GL186_RS05180	COG1597	lipid kinase activity
GL186_RS05185	COG0366	Alpha amylase catalytic
GL186_RS05195	COG1396	sequence-specific DNA binding
GL186_RS05200	COG0542	response to heat
GL186_RS05225	COG3843	relaxase mobilization nuclease domain protein
GL186_RS05255	COG1131	(ABC) transporter
GL186_RS05280	COG0772	Belongs to the SEDS family
GL186_RS05285	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GL186_RS05300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GL186_RS05305	COG0358	DNA primase activity
GL186_RS05310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GL186_RS05315	COG2151	metal-sulfur cluster biosynthetic enzyme
GL186_RS05320	COG0438	transferase activity, transferring glycosyl groups
GL186_RS05325	COG0438	transferase activity, transferring glycosyl groups
GL186_RS05350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GL186_RS05360	COG4109	DRTGG domain
GL186_RS05365	COG0024	Methionine aminopeptidase
GL186_RS05375	COG0210	DNA helicase
GL186_RS05385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GL186_RS05405	COG1104	cysteine desulfurase activity
GL186_RS05410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GL186_RS05420	COG2357	RelA SpoT domain protein
GL186_RS05430	COG0564	pseudouridine synthase activity
GL186_RS05435	COG0280	phosphate acetyltransferase
GL186_RS05475	COG0196	riboflavin kinase activity
GL186_RS05480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GL186_RS05485	COG1307	EDD domain protein, DegV family
GL186_RS05495	COG0488	(ABC) transporter
GL186_RS05505	COG2814	Major facilitator Superfamily
GL186_RS05515	COG1523	belongs to the glycosyl hydrolase 13 family
GL186_RS05520	COG1012	belongs to the aldehyde dehydrogenase family
GL186_RS05525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GL186_RS05535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GL186_RS05545	COG0560	Phosphoserine phosphatase
GL186_RS05550	COG0560	Phosphoserine phosphatase
GL186_RS05570	COG0582	viral genome integration into host DNA
GL186_RS05590	COG1074	ATP-dependent DNA helicase activity
GL186_RS05600	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GL186_RS05600	COG3583	domain protein
GL186_RS05605	COG3064	Membrane
GL186_RS05610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GL186_RS05630	COG0095	Lipoate-protein ligase
GL186_RS05635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GL186_RS05640	COG0508	dehydrogenase complex catalyzes the overall conversion of
GL186_RS05645	COG0022	dehydrogenase e1 component
GL186_RS05650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GL186_RS05655	COG0534	Mate efflux family protein
GL186_RS05665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GL186_RS05670	COG1051	belongs to the nudix hydrolase family
GL186_RS05685	COG1011	Hydrolase
GL186_RS05690	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GL186_RS05710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL186_RS05715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GL186_RS05720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GL186_RS05725	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GL186_RS05755	COG3711	transcriptional antiterminator
GL186_RS05760	COG3684	Belongs to the aldolase LacD family
GL186_RS05815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GL186_RS05820	COG0497	DNA recombination
GL186_RS05825	COG1438	arginine binding
GL186_RS05830	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GL186_RS05860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GL186_RS05880	COG3764	Sortase (surface protein transpeptidase)
GL186_RS05885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GL186_RS05915	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GL186_RS05920	COG5002	protein histidine kinase activity
GL186_RS05925	COG0745	RESPONSE REGULATOR receiver
GL186_RS05930	COG1194	a g-specific adenine glycosylase
GL186_RS05945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GL186_RS05950	COG4684	Psort location CytoplasmicMembrane, score
GL186_RS05960	COG1827	regulation of RNA biosynthetic process
GL186_RS05965	COG2816	NAD+ diphosphatase activity
GL186_RS05990	COG0765	amino acid transport
GL186_RS05995	COG1126	abc transporter atp-binding protein
GL186_RS06000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GL186_RS06005	COG0552	protein localization to endoplasmic reticulum
GL186_RS06010	COG0561	phosphatase activity
GL186_RS06015	COG0561	phosphatase activity
GL186_RS06020	COG1196	nuclear chromosome segregation
GL186_RS06045	COG1401	restriction endodeoxyribonuclease activity
GL186_RS06055	COG0066	3-isopropylmalate dehydratase activity
GL186_RS06065	COG0473	3-isopropylmalate dehydrogenase activity
GL186_RS06080	COG3142	Participates in the control of copper homeostasis
GL186_RS06085	COG2832	Protein of unknown function (DUF454)
GL186_RS06090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GL186_RS06100	COG0758	DNA mediated transformation
GL186_RS06105	COG4750	Nucleotidyl transferase
GL186_RS06120	COG1063	alcohol dehydrogenase
GL186_RS06125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GL186_RS06135	COG3475	LICD family
GL186_RS06140	COG3475	LICD family
GL186_RS06150	COG0505	Belongs to the CarA family
GL186_RS06165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GL186_RS06180	COG0488	(ABC) transporter
GL186_RS06190	COG1704	LemA family
GL186_RS06205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GL186_RS06220	COG1078	dGTPase activity
GL186_RS06240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GL186_RS06245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GL186_RS06250	COG0077	Prephenate dehydratase
GL186_RS06250	COG1605	Chorismate mutase
GL186_RS06255	COG0716	FMN binding
GL186_RS06260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GL186_RS06290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GL186_RS06370	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GL186_RS06375	COG1269	ATP hydrolysis coupled proton transport
GL186_RS06390	COG0673	inositol 2-dehydrogenase activity
GL186_RS06395	COG4409	exo-alpha-(2->6)-sialidase activity
GL186_RS06405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GL186_RS06410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GL186_RS06415	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GL186_RS06420	COG1737	Transcriptional regulator
GL186_RS06445	COG1136	(ABC) transporter
GL186_RS06445	COG0577	efflux transmembrane transporter activity
GL186_RS06455	COG0515	serine threonine protein kinase
GL186_RS06505	COG0402	S-adenosylhomocysteine deaminase activity
GL186_RS06515	COG1132	(ABC) transporter
GL186_RS06520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GL186_RS06520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GL186_RS06555	COG1215	transferase activity, transferring glycosyl groups
GL186_RS06565	COG3475	LICD family
GL186_RS06575	COG0077	Prephenate dehydratase
GL186_RS06580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GL186_RS06585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GL186_RS06595	COG0287	Prephenate dehydrogenase
GL186_RS06620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GL186_RS06630	COG4555	ABC transporter
GL186_RS06670	COG3842	ATPase activity
GL186_RS06685	COG3527	Alpha-acetolactate decarboxylase
GL186_RS06690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GL186_RS06695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL186_RS06700	COG0704	Plays a role in the regulation of phosphate uptake
GL186_RS06705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GL186_RS06710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GL186_RS06715	COG0581	inorganic phosphate transmembrane transporter activity
GL186_RS06720	COG0573	inorganic phosphate transmembrane transporter activity
GL186_RS06725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GL186_RS06730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GL186_RS06730	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GL186_RS06735	COG0483	inositol monophosphate 1-phosphatase activity
GL186_RS06745	COG1393	Belongs to the ArsC family
GL186_RS06755	COG0647	UMP catabolic process
GL186_RS06765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GL186_RS06815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GL186_RS06825	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GL186_RS06860	COG0826	peptidase U32
GL186_RS06890	COG1132	(ABC) transporter
GL186_RS06905	COG1129	ABC transporter
GL186_RS06945	COG2188	Transcriptional regulator
GL186_RS06950	COG0697	spore germination
GL186_RS06955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GL186_RS06970	COG0561	phosphatase activity
GL186_RS06995	COG0492	ferredoxin-NADP+ reductase activity
GL186_RS07005	COG1126	abc transporter atp-binding protein
GL186_RS07015	COG1393	Belongs to the ArsC family
GL186_RS07035	COG1272	protein, Hemolysin III
GL186_RS07065	COG0431	NADPH-dependent FMN reductase
GL186_RS07065	COG1053	succinate dehydrogenase
GL186_RS07065	COG3976	FMN-binding domain protein
GL186_RS07090	COG0656	L-ascorbic acid biosynthetic process
GL186_RS07100	COG0726	polysaccharide deacetylase
GL186_RS07115	COG0513	Belongs to the DEAD box helicase family
GL186_RS07130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GL186_RS07165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GL186_RS07175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GL186_RS07180	COG1126	abc transporter atp-binding protein
GL186_RS07195	COG0628	permease
GL186_RS07200	COG2706	6-phosphogluconolactonase activity
GL186_RS07265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GL186_RS07290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GL186_RS07295	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GL186_RS07300	COG0626	cystathionine gamma-synthase activity
GL186_RS07310	COG4166	transmembrane transport
GL186_RS07315	COG2244	polysaccharide biosynthetic process
GL186_RS07320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GL186_RS07325	COG3237	CsbD-like
GL186_RS07345	COG2827	Endonuclease containing a URI domain
GL186_RS07350	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GL186_RS07355	COG1098	S1 RNA binding domain
GL186_RS07365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GL186_RS07370	COG0629	single-stranded DNA binding
GL186_RS07380	COG0017	Asparaginyl-tRNA synthetase
GL186_RS07390	COG0436	Aminotransferase
GL186_RS07420	COG0242	peptide deformylase activity
GL186_RS07425	COG0625	glutathione transferase activity
GL186_RS07435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GL186_RS07440	COG0488	(ABC) transporter
GL186_RS07445	COG0617	tRNA 3'-terminal CCA addition
GL186_RS07455	COG1307	EDD domain protein, DegV family
GL186_RS07475	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GL186_RS07485	COG1481	regulation of sporulation
GL186_RS07490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GL186_RS07500	COG0251	oxidation-reduction process
GL186_RS07520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GL186_RS07530	COG5263	repeat protein
GL186_RS07530	COG4193	domain, Protein
GL186_RS07540	COG3935	DnaD domain protein
GL186_RS07555	COG2226	methyltransferase
GL186_RS07565	COG3842	ATPase activity
GL186_RS07575	COG1335	isochorismatase
GL186_RS07585	COG0513	Belongs to the DEAD box helicase family
GL186_RS07590	COG2223	nitrite transmembrane transporter activity
GL186_RS07595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GL186_RS07600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GL186_RS07605	COG3442	glutamine amidotransferase
GL186_RS07610	COG0006	proline dipeptidase activity
GL186_RS07625	COG4720	Psort location CytoplasmicMembrane, score
GL186_RS07630	COG0351	phosphomethylpyrimidine kinase
GL186_RS07650	COG2824	Alkylphosphonate utilization operon protein PhnA
GL186_RS07670	COG0463	Glycosyl transferase, family 2
GL186_RS07675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GL186_RS07685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GL186_RS07690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GL186_RS07695	COG2384	SAM-dependent methyltransferase
GL186_RS07700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GL186_RS07705	COG0204	Acyl-transferase
GL186_RS07720	COG2910	NAD(P)H-binding
GL186_RS07740	COG5002	protein histidine kinase activity
GL186_RS07745	COG0745	RESPONSE REGULATOR receiver
GL186_RS07760	COG1959	2 iron, 2 sulfur cluster binding
GL186_RS07805	COG3590	peptidase
GL186_RS07820	COG0803	Belongs to the bacterial solute-binding protein 9 family
GL186_RS07825	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GL186_RS07835	COG0577	efflux transmembrane transporter activity
GL186_RS07835	COG1136	(ABC) transporter
GL186_RS07865	COG3599	regulation of cell shape
GL186_RS07885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GL186_RS07905	COG1051	belongs to the nudix hydrolase family
GL186_RS07910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GL186_RS07925	COG0768	penicillin binding
GL186_RS07940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GL186_RS07955	COG2731	YhcH YjgK YiaL family protein
GL186_RS07960	COG0395	ABC-type sugar transport system, permease component
GL186_RS07965	COG1175	transmembrane transport
GL186_RS07975	COG2190	(PTS) system
GL186_RS07975	COG1263	PTS System
GL186_RS07975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL186_RS07990	COG4409	exo-alpha-(2->6)-sialidase activity
GL186_RS08000	COG1175	transmembrane transport
GL186_RS08005	COG1653	transport
GL186_RS08025	COG3458	cephalosporin-C deacetylase activity
GL186_RS08030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GL186_RS08045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GL186_RS08050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GL186_RS08055	COG0653	protein targeting
GL186_RS08065	COG1131	(ABC) transporter
GL186_RS08105	COG0778	Nitroreductase
GL186_RS08110	COG1484	DNA-dependent DNA replication
GL186_RS08125	COG1725	Transcriptional regulator
GL186_RS08130	COG1131	(ABC) transporter
GL186_RS08140	COG1668	transmembrane transport
GL186_RS08145	COG4152	abc transporter atp-binding protein
GL186_RS08165	COG1940	carbohydrate kinase activity
GL186_RS08170	COG1263	PTS System
GL186_RS08170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL186_RS08170	COG2190	(PTS) system
GL186_RS08175	COG1621	beta-fructofuranosidase activity
GL186_RS08180	COG1609	Transcriptional regulator
GL186_RS08190	COG3425	synthase
GL186_RS08215	COG0515	serine threonine protein kinase
GL186_RS08215	COG2815	serine threonine protein kinase
GL186_RS08220	COG0631	protein serine/threonine phosphatase activity
GL186_RS08225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GL186_RS08225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GL186_RS08235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GL186_RS08245	COG0194	GDP metabolic process
GL186_RS08265	COG2226	methyltransferase
GL186_RS08270	COG0799	negative regulation of ribosome biogenesis
GL186_RS08280	COG1713	HD superfamily hydrolase involved in NAD metabolism
GL186_RS08285	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GL186_RS08290	COG1534	Rna-binding protein
GL186_RS08295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GL186_RS08310	COG0668	transmembrane transport
GL186_RS08335	COG3118	belongs to the thioredoxin family
GL186_RS08340	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GL186_RS08350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GL186_RS08365	COG1131	(ABC) transporter
GL186_RS08370	COG0640	Transcriptional regulator
GL186_RS08375	COG1164	Oligoendopeptidase f
GL186_RS08380	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GL186_RS08395	COG1051	belongs to the nudix hydrolase family
GL186_RS08430	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GL186_RS08440	COG1621	beta-fructofuranosidase activity
GL186_RS08445	COG1653	transport
GL186_RS08450	COG0395	ABC-type sugar transport system, permease component
GL186_RS08455	COG4209	transmembrane transport
GL186_RS08465	COG3711	transcriptional antiterminator
GL186_RS08470	COG2261	transglycosylase associated protein
GL186_RS08490	COG3237	CsbD-like
GL186_RS08510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GL186_RS08520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL186_RS08525	COG1447	Phosphotransferase system cellobiose-specific component IIA
GL186_RS08530	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL186_RS08540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL186_RS08545	COG1846	Transcriptional regulator
GL186_RS08545	COG1940	carbohydrate kinase activity
GL186_RS08585	COG0135	phosphoribosylanthranilate isomerase activity
GL186_RS08600	COG0512	Glutamine amidotransferase of anthranilate synthase
GL186_RS08605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GL186_RS08630	COG1285	pathogenesis
GL186_RS08635	COG1178	ABC-type Fe3 transport system permease component
GL186_RS08660	COG5434	Belongs to the glycosyl hydrolase 28 family
GL186_RS08665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GL186_RS08670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GL186_RS08675	COG1132	(ABC) transporter
GL186_RS08680	COG1132	(ABC) transporter
GL186_RS08695	COG0708	Exodeoxyribonuclease III
GL186_RS08715	COG2233	PERMEase
GL186_RS08740	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GL186_RS08745	COG1609	Transcriptional regulator
GL186_RS08750	COG1063	alcohol dehydrogenase
GL186_RS08755	COG0789	Transcriptional regulator
GL186_RS08760	COG1230	cation diffusion facilitator family transporter
GL186_RS08770	COG3201	nicotinamide mononucleotide transporter
GL186_RS08775	COG1174	glycine betaine transport
GL186_RS08780	COG1125	glycine betaine transport
GL186_RS08780	COG0517	IMP dehydrogenase activity
GL186_RS08800	COG1363	Peptidase, m42
GL186_RS08810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GL186_RS08815	COG4605	iron ion homeostasis
GL186_RS08820	COG4604	ABC transporter, ATP-binding protein
GL186_RS08825	COG4607	ABC-type enterochelin transport system periplasmic component
GL186_RS08835	COG1187	pseudouridine synthase activity
GL186_RS08855	COG0517	IMP dehydrogenase activity
GL186_RS08865	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GL186_RS08880	COG0366	Alpha amylase catalytic
GL186_RS08885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL186_RS08885	COG1263	PTS System
GL186_RS08890	COG2188	Transcriptional regulator
GL186_RS08895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GL186_RS08900	COG4120	Belongs to the binding-protein-dependent transport system permease family
GL186_RS08910	COG4608	Belongs to the ABC transporter superfamily
GL186_RS08915	COG0444	Belongs to the ABC transporter superfamily
GL186_RS08920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GL186_RS08925	COG0601	transmembrane transport
GL186_RS08930	COG4166	transmembrane transport
GL186_RS08945	COG0366	Alpha amylase catalytic
GL186_RS08955	COG0395	ABC-type sugar transport system, permease component
GL186_RS08960	COG1175	transmembrane transport
GL186_RS08965	COG1653	transport
GL186_RS08970	COG3345	alpha-galactosidase
GL186_RS08975	COG2207	Transcriptional regulator
GL186_RS08980	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GL186_RS08980	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GL186_RS09100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GL186_RS09140	COG4221	oxidoreductase activity
GL186_RS09145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GL186_RS09150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GL186_RS09270	COG5263	repeat protein
GL186_RS09270	COG5632	N-Acetylmuramoyl-L-alanine amidase
GL186_RS09290	COG1316	TRANSCRIPTIONal
GL186_RS09300	COG0802	atpase or kinase
GL186_RS09325	COG0577	efflux transmembrane transporter activity
GL186_RS09325	COG1136	(ABC) transporter
GL186_RS09355	COG1253	flavin adenine dinucleotide binding
GL186_RS09370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GL186_RS09380	COG3480	Lon protease (S16) C-terminal proteolytic domain
GL186_RS09390	COG0742	ribosomal rna small subunit methyltransferase
GL186_RS09405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GL186_RS09410	COG1254	Belongs to the acylphosphatase family
GL186_RS09420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GL186_RS09430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GL186_RS09445	COG1564	THIamine pyrophosphokinase
GL186_RS09455	COG1162	GTPase activity
GL186_RS09490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GL186_RS09495	COG0084	hydrolase, TatD family'
GL186_RS09510	COG0436	Aminotransferase
GL186_RS09520	COG0589	response to stress
GL186_RS09525	COG0561	phosphatase activity
GL186_RS09530	COG0252	asparaginase activity
GL186_RS09535	COG1609	Transcriptional regulator
GL186_RS09540	COG2197	response regulator
GL186_RS09545	COG4585	Histidine kinase
GL186_RS09550	COG0842	Transport permease protein
GL186_RS09555	COG1131	(ABC) transporter
GL186_RS09655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GL186_RS09660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GL186_RS09665	COG0564	pseudouridine synthase activity
GL186_RS09675	COG0577	efflux transmembrane transporter activity
GL186_RS09685	COG0157	Belongs to the NadC ModD family
GL186_RS09695	COG1129	ABC transporter
GL186_RS09700	COG2188	Transcriptional regulator
GL186_RS09705	COG2723	6-phospho-beta-galactosidase activity
GL186_RS09710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GL186_RS09720	COG1447	Phosphotransferase system cellobiose-specific component IIA
GL186_RS09725	COG1012	belongs to the aldehyde dehydrogenase family
GL186_RS09725	COG1454	alcohol dehydrogenase
GL186_RS09735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GL186_RS09745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GL186_RS09765	COG3623	hexulose-6-phosphate isomerase
GL186_RS09775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL186_RS09785	COG3037	sugar-specific permease SgaT UlaA
GL186_RS09795	COG1847	R3H domain protein
GL186_RS09800	COG0706	membrane insertase activity
GL186_RS09820	COG2226	methyltransferase
GL186_RS09845	COG4537	Required for transformation and DNA binding
GL186_RS09850	COG1459	type II secretion system
GL186_RS09855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GL186_RS09865	COG1063	alcohol dehydrogenase
GL186_RS09890	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GL186_RS09895	COG3759	membrane
GL186_RS09910	COG0131	Imidazoleglycerol-phosphate dehydratase
GL186_RS09910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GL186_RS09915	COG0534	Mate efflux family protein
GL186_RS10030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GL186_RS10035	COG1132	(ABC) transporter
GL186_RS10045	COG1132	(ABC) transporter
GL186_RS10055	COG1438	arginine binding
GL186_RS10080	COG0745	RESPONSE REGULATOR receiver
GL186_RS10085	COG5002	protein histidine kinase activity
GL186_RS10090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GL186_RS10095	COG0573	inorganic phosphate transmembrane transporter activity
GL186_RS10105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GL186_RS10110	COG0704	Plays a role in the regulation of phosphate uptake
GL186_RS10130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GL186_RS10140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GL186_RS10155	COG0697	spore germination
GL186_RS10160	COG4499	WXG100 protein secretion system (Wss), protein YukC
GL186_RS10160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GL186_RS10170	COG2217	Heavy metal translocating P-type atpase
GL186_RS10180	COG2226	methyltransferase
GL186_RS10190	COG0058	SHG alpha-glucan phosphorylase activity
GL186_RS10195	COG1640	4-alpha-glucanotransferase
GL186_RS10200	COG2182	Extracellular solute-binding protein
GL186_RS10205	COG1175	transmembrane transport
GL186_RS10210	COG3833	ABC-type maltose transport systems, permease component
GL186_RS10215	COG5521	maltodextrose utilization protein MalA
GL186_RS10220	COG1609	Transcriptional regulator
GL186_RS10230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GL186_RS10265	COG1476	TRANSCRIPTIONal
GL186_RS10295	COG2151	metal-sulfur cluster biosynthetic enzyme
GL186_RS10310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GL186_RS10315	COG3959	Transketolase, thiamine diphosphate binding domain
GL186_RS10330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GL186_RS10350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GL186_RS10385	COG0383	alpha-mannosidase activity
GL186_RS10395	COG3537	Alpha-1,2-mannosidase
GL186_RS10415	COG0549	Belongs to the carbamate kinase family
GL186_RS10420	COG1288	antiporter activity
GL186_RS10425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GL186_RS10445	COG1454	alcohol dehydrogenase
GL186_RS10465	COG3716	PTS system mannose fructose sorbose family IID component
GL186_RS10475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GL186_RS10495	COG1070	Carbohydrate kinase
GL186_RS10505	COG3443	Belongs to the bacterial solute-binding protein 9 family
GL186_RS10505	COG0803	Belongs to the bacterial solute-binding protein 9 family
GL186_RS10510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GL186_RS10515	COG1121	(ABC) transporter
GL186_RS10520	COG1846	Transcriptional regulator
GL186_RS10525	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GL186_RS10535	COG1696	Membrane protein involved in D-alanine export
GL186_RS10550	COG2211	Major facilitator Superfamily
GL186_RS10570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GL186_RS10575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GL186_RS10595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GL186_RS10605	COG1755	Isoprenylcysteine carboxyl methyltransferase
GL186_RS10610	COG5002	protein histidine kinase activity
GL186_RS10615	COG0745	RESPONSE REGULATOR receiver
GL186_RS10620	COG0542	response to heat
GL186_RS10625	COG4463	regulation of RNA biosynthetic process
GL186_RS10630	COG1116	anion transmembrane transporter activity
GL186_RS10635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GL186_RS10640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GL186_RS10660	COG0305	Participates in initiation and elongation during chromosome replication
GL186_RS10680	COG1040	competence protein
GL186_RS10685	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GL186_RS10690	COG1739	Uncharacterized protein family UPF0029
GL186_RS10725	COG3942	CHAP domain
GL186_RS10735	COG1792	Involved in formation and maintenance of cell shape
GL186_RS10740	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GL186_RS10745	COG1122	ATPase activity
GL186_RS10750	COG1122	ATPase activity
GL186_RS10755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GL186_RS10765	COG0612	Peptidase, M16
GL186_RS10770	COG0612	Peptidase, M16
GL186_RS10775	COG2501	S4 domain
GL186_RS10785	COG0517	IMP dehydrogenase activity
GL186_RS10785	COG0516	GMP reductase activity
GL186_RS10790	COG0180	Tryptophanyl-tRNA synthetase
GL186_RS10795	COG0488	(ABC) transporter
GL186_RS10805	COG1511	domain protein
GL186_RS10815	COG1511	domain protein
GL186_RS10860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GL186_RS10865	COG1475	DNA binding