locus-tag	class	description
SP670_RS00010	COG0592	DNA-directed DNA polymerase activity
SP670_RS00105	COG3645	SOS response
SP670_RS00110	COG4974	Belongs to the 'phage' integrase family
SP670_RS00115	COG0012	GTP binding
SP670_RS00125	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SP670_RS00130	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SP670_RS00155	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SP670_RS00160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SP670_RS00275	COG2189	Belongs to the N(4) N(6)-methyltransferase family
SP670_RS00355	COG0582	viral genome integration into host DNA
SP670_RS00485	COG5632	N-Acetylmuramoyl-L-alanine amidase
SP670_RS00485	COG5263	repeat protein
SP670_RS00505	COG0756	dUTP diphosphatase activity
SP670_RS00515	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SP670_RS00530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SP670_RS00550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SP670_RS00550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SP670_RS00555	COG1832	CoA-binding protein
SP670_RS00565	COG2855	membrane
SP670_RS00570	COG0436	Aminotransferase
SP670_RS00585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SP670_RS00610	COG2274	protein secretion by the type I secretion system
SP670_RS00615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SP670_RS00625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SP670_RS00630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SP670_RS00640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SP670_RS00655	COG0151	Belongs to the GarS family
SP670_RS00660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SP670_RS00675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SP670_RS00680	COG3583	domain protein
SP670_RS00680	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SP670_RS00680	COG3064	Membrane
SP670_RS00695	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SP670_RS00700	COG3715	PTS system
SP670_RS00705	COG3716	PTS system mannose fructose sorbose family IID component
SP670_RS00715	COG2222	sugar isomerase
SP670_RS00725	COG2514	catechol 2,3-dioxygenase activity
SP670_RS00730	COG1937	Protein conserved in bacteria
SP670_RS00755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SP670_RS00760	COG0569	domain protein
SP670_RS00770	COG1215	transferase activity, transferring glycosyl groups
SP670_RS00790	COG5002	protein histidine kinase activity
SP670_RS00810	COG4209	transmembrane transport
SP670_RS00815	COG0395	ABC-type sugar transport system, permease component
SP670_RS00825	COG1653	transport
SP670_RS00855	COG1695	Transcriptional regulator
SP670_RS00880	COG0546	phosphoglycolate phosphatase activity
SP670_RS00885	COG1760	l-serine dehydratase
SP670_RS00890	COG1760	l-serine dehydratase
SP670_RS00920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SP670_RS01035	COG0494	nUDIX hydrolase
SP670_RS01040	COG0445	tRNA wobble uridine modification
SP670_RS01065	COG1214	PFAM Peptidase M22, glycoprotease
SP670_RS01105	COG0438	transferase activity, transferring glycosyl groups
SP670_RS01130	COG1396	sequence-specific DNA binding
SP670_RS01165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SP670_RS01170	COG1464	Belongs to the NlpA lipoprotein family
SP670_RS01175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SP670_RS01180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SP670_RS01200	COG2972	Histidine kinase
SP670_RS01205	COG4753	response regulator
SP670_RS01205	COG2207	Transcriptional regulator
SP670_RS01215	COG1780	Probably involved in ribonucleotide reductase function
SP670_RS01270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SP670_RS01270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SP670_RS01290	COG2818	Glycosylase
SP670_RS01315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SP670_RS01320	COG0006	proline dipeptidase activity
SP670_RS01335	COG1393	Belongs to the ArsC family
SP670_RS01360	COG0285	dihydrofolate synthase activity
SP670_RS01370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SP670_RS01435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SP670_RS01460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SP670_RS01500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SP670_RS01515	COG0201	protein transport
SP670_RS01525	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SP670_RS01530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SP670_RS01540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SP670_RS01545	COG0202	RNA polymerase activity
SP670_RS01555	COG3830	Belongs to the UPF0237 family
SP670_RS01560	COG2848	UPF0210 protein
SP670_RS01600	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SP670_RS01605	COG1349	DNA-binding transcription factor activity
SP670_RS01615	COG1447	Phosphotransferase system cellobiose-specific component IIA
SP670_RS01620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SP670_RS01625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SP670_RS01630	COG1882	Formate acetyltransferase
SP670_RS01680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SP670_RS01685	COG4589	Belongs to the CDS family
SP670_RS01690	COG0750	zinc metalloprotease
SP670_RS01700	COG2723	6-phospho-beta-galactosidase activity
SP670_RS01705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SP670_RS01720	COG1523	belongs to the glycosyl hydrolase 13 family
SP670_RS01740	COG2176	DNA-directed DNA polymerase activity
SP670_RS01760	COG2309	aminopeptidase activity
SP670_RS01765	COG2261	transglycosylase associated protein
SP670_RS01775	COG1187	pseudouridine synthase activity
SP670_RS01785	COG3579	cysteine-type endopeptidase activity
SP670_RS01790	COG3716	PTS system mannose fructose sorbose family IID component
SP670_RS01795	COG3715	PTS system
SP670_RS01805	COG1064	alcohol dehydrogenase
SP670_RS01815	COG0561	phosphatase activity
SP670_RS01820	COG2252	PERMEase
SP670_RS01830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SP670_RS01835	COG0285	dihydrofolate synthase activity
SP670_RS01845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SP670_RS01845	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SP670_RS01855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SP670_RS01875	COG2723	6-phospho-beta-galactosidase activity
SP670_RS01890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SP670_RS01890	COG3711	transcriptional antiterminator
SP670_RS01905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SP670_RS01920	COG0386	Belongs to the glutathione peroxidase family
SP670_RS01925	COG5492	domain, Protein
SP670_RS01960	COG1028	Short-chain dehydrogenase reductase Sdr
SP670_RS01970	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SP670_RS01975	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SP670_RS01980	COG3715	PTS system
SP670_RS01985	COG3716	PTS system mannose fructose sorbose family IID component
SP670_RS02000	COG1609	Transcriptional regulator
SP670_RS02035	COG4839	cell division protein FtsL
SP670_RS02040	COG0768	penicillin binding
SP670_RS02065	COG0366	Alpha amylase catalytic
SP670_RS02070	COG2801	Transposase and inactivated derivatives
SP670_RS02100	COG4464	protein tyrosine phosphatase activity
SP670_RS02105	COG3944	biosynthesis protein
SP670_RS02120	COG1442	glycosyl transferase family 8
SP670_RS02135	COG0463	Glycosyl transferase, family 2
SP670_RS02150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SP670_RS02160	COG1088	dTDP-glucose 4,6-dehydratase activity
SP670_RS02165	COG1091	dTDP-4-dehydrorhamnose reductase activity
SP670_RS02175	COG4372	Transposase
SP670_RS02185	COG4166	transmembrane transport
SP670_RS02190	COG0366	Alpha amylase catalytic
SP670_RS02195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SP670_RS02220	COG0116	Belongs to the methyltransferase superfamily
SP670_RS02230	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SP670_RS02235	COG0745	RESPONSE REGULATOR receiver
SP670_RS02285	COG4585	Histidine kinase
SP670_RS02290	COG2197	response regulator
SP670_RS02330	COG2801	Transposase and inactivated derivatives
SP670_RS02345	COG2213	PTS system mannitol-specific
SP670_RS02350	COG3711	transcriptional antiterminator
SP670_RS02355	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SP670_RS02375	COG0544	peptidyl-prolyl cis-trans isomerase activity
SP670_RS02380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SP670_RS02385	COG0681	Belongs to the peptidase S26 family
SP670_RS02420	COG1115	amino acid carrier protein
SP670_RS02445	COG0527	aspartate kinase activity
SP670_RS02450	COG1024	Enoyl-CoA hydratase
SP670_RS02455	COG1846	Transcriptional regulator
SP670_RS02465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SP670_RS02475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SP670_RS02480	COG1028	Short-chain dehydrogenase reductase Sdr
SP670_RS02485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SP670_RS02500	COG0439	Biotin carboxylase
SP670_RS02505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SP670_RS02555	COG1063	alcohol dehydrogenase
SP670_RS02585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SP670_RS02595	COG1461	Dihydroxyacetone kinase
SP670_RS02600	COG0028	Belongs to the TPP enzyme family
SP670_RS02605	COG0440	acetolactate synthase activity
SP670_RS02625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SP670_RS02640	COG0765	amino acid transport
SP670_RS02670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SP670_RS02675	COG1882	Formate acetyltransferase
SP670_RS02745	COG1940	carbohydrate kinase activity
SP670_RS02745	COG1846	Transcriptional regulator
SP670_RS02750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SP670_RS02760	COG1447	Phosphotransferase system cellobiose-specific component IIA
SP670_RS02765	COG2723	6-phospho-beta-galactosidase activity
SP670_RS02770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SP670_RS02770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SP670_RS02775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SP670_RS02780	COG0569	domain protein
SP670_RS02800	COG1122	ATPase activity
SP670_RS02815	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SP670_RS02820	COG0671	phosphoesterase, PA-phosphatase related
SP670_RS02830	COG1247	-acetyltransferase
SP670_RS02845	COG0504	CTP synthase activity
SP670_RS02850	COG1283	sodium-dependent phosphate transmembrane transporter activity
SP670_RS02870	COG0789	Transcriptional regulator
SP670_RS02875	COG0174	glutamine synthetase
SP670_RS02885	COG0732	type I restriction modification DNA specificity domain
SP670_RS02895	COG4974	Belongs to the 'phage' integrase family
SP670_RS02945	COG0484	heat shock protein binding
SP670_RS02955	COG0537	adenosine 5'-monophosphoramidase activity
SP670_RS02960	COG1131	(ABC) transporter
SP670_RS02985	COG3290	protein histidine kinase activity
SP670_RS02995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SP670_RS03000	COG2274	protein secretion by the type I secretion system
SP670_RS03055	COG1266	CAAX protease self-immunity
SP670_RS03075	COG0195	Participates in both transcription termination and antitermination
SP670_RS03080	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SP670_RS03135	COG0519	Catalyzes the synthesis of GMP from XMP
SP670_RS03145	COG0525	valine-tRNA ligase activity
SP670_RS03165	COG2801	Transposase and inactivated derivatives
SP670_RS03200	COG3711	transcriptional antiterminator
SP670_RS03205	COG1263	PTS System
SP670_RS03205	COG2190	(PTS) system
SP670_RS03205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SP670_RS03220	COG0456	acetyltransferase
SP670_RS03225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SP670_RS03225	COG0072	phenylalanine-tRNA ligase activity
SP670_RS03240	COG3620	sequence-specific DNA binding
SP670_RS03260	COG1045	serine acetyltransferase
SP670_RS03270	COG0215	cysteine-tRNA ligase activity
SP670_RS03275	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SP670_RS03295	COG0577	efflux transmembrane transporter activity
SP670_RS03300	COG1136	(ABC) transporter
SP670_RS03305	COG0577	efflux transmembrane transporter activity
SP670_RS03310	COG0745	RESPONSE REGULATOR receiver
SP670_RS03315	COG5002	protein histidine kinase activity
SP670_RS03320	COG0191	fructose-bisphosphate aldolase activity
SP670_RS03325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SP670_RS03330	COG0765	amino acid transport
SP670_RS03335	COG0765	amino acid transport
SP670_RS03340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SP670_RS03350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SP670_RS03350	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SP670_RS03380	COG0322	excinuclease ABC activity
SP670_RS03390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SP670_RS03405	COG1573	uracil-dna glycosylase
SP670_RS03415	COG1114	Component of the transport system for branched-chain amino acids
SP670_RS03420	COG1363	Peptidase, m42
SP670_RS03465	COG4555	ABC transporter
SP670_RS03500	COG1404	Belongs to the peptidase S8 family
SP670_RS03515	COG3775	system Galactitol-specific IIC component
SP670_RS03525	COG3250	beta-galactosidase activity
SP670_RS03550	COG1242	4 iron, 4 sulfur cluster binding
SP670_RS03555	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SP670_RS03575	COG0785	Cytochrome C biogenesis protein
SP670_RS03580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SP670_RS03585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SP670_RS03585	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SP670_RS03595	COG2207	Transcriptional regulator
SP670_RS03595	COG4753	response regulator
SP670_RS03600	COG2972	Histidine kinase
SP670_RS03610	COG3064	Membrane
SP670_RS03615	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SP670_RS03625	COG4193	domain, Protein
SP670_RS03625	COG5263	repeat protein
SP670_RS03630	COG1940	carbohydrate kinase activity
SP670_RS03645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SP670_RS03650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SP670_RS03655	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SP670_RS03665	COG0300	oxidoreductase activity
SP670_RS03680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SP670_RS03690	COG1187	pseudouridine synthase activity
SP670_RS03695	COG1217	gtp-binding protein TYPA
SP670_RS03715	COG1136	(ABC) transporter
SP670_RS03730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SP670_RS03740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SP670_RS03765	COG1131	(ABC) transporter
SP670_RS03770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SP670_RS03780	COG1126	abc transporter atp-binding protein
SP670_RS03800	COG1304	FMN binding
SP670_RS03810	COG1304	FMN binding
SP670_RS03825	COG0352	thiamine-phosphate diphosphorylase activity
SP670_RS03835	COG4172	Belongs to the ABC transporter superfamily
SP670_RS03845	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SP670_RS03860	COG0352	thiamine-phosphate diphosphorylase activity
SP670_RS03880	COG2217	Heavy metal translocating P-type atpase
SP670_RS03885	COG0028	Belongs to the TPP enzyme family
SP670_RS03895	COG3335	DDE superfamily endonuclease
SP670_RS03905	COG2723	6-phospho-beta-galactosidase activity
SP670_RS03910	COG1482	cell wall glycoprotein biosynthetic process
SP670_RS03915	COG0733	neurotransmitter:sodium symporter activity
SP670_RS03925	COG0789	Transcriptional regulator
SP670_RS03940	COG2706	6-phosphogluconolactonase activity
SP670_RS03945	COG0628	permease
SP670_RS03960	COG1126	abc transporter atp-binding protein
SP670_RS03965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SP670_RS03975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SP670_RS04010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SP670_RS04025	COG3335	DDE superfamily endonuclease
SP670_RS04030	COG3335	DDE superfamily endonuclease
SP670_RS04055	COG0656	L-ascorbic acid biosynthetic process
SP670_RS04080	COG0431	NADPH-dependent FMN reductase
SP670_RS04080	COG1053	succinate dehydrogenase
SP670_RS04080	COG3976	FMN-binding domain protein
SP670_RS04110	COG1272	protein, Hemolysin III
SP670_RS04125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SP670_RS04130	COG1393	Belongs to the ArsC family
SP670_RS04140	COG1126	abc transporter atp-binding protein
SP670_RS04150	COG0492	ferredoxin-NADP+ reductase activity
SP670_RS04185	COG0561	phosphatase activity
SP670_RS04200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SP670_RS04205	COG0697	spore germination
SP670_RS04210	COG2188	Transcriptional regulator
SP670_RS04240	COG4372	Transposase
SP670_RS04250	COG1129	ABC transporter
SP670_RS04265	COG1132	(ABC) transporter
SP670_RS04270	COG1132	(ABC) transporter
SP670_RS04295	COG0826	peptidase U32
SP670_RS04310	COG1131	(ABC) transporter
SP670_RS04330	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SP670_RS04340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SP670_RS04390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SP670_RS04400	COG0647	UMP catabolic process
SP670_RS04410	COG1393	Belongs to the ArsC family
SP670_RS04420	COG0483	inositol monophosphate 1-phosphatase activity
SP670_RS04425	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SP670_RS04425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SP670_RS04430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SP670_RS04435	COG0573	inorganic phosphate transmembrane transporter activity
SP670_RS04440	COG0581	inorganic phosphate transmembrane transporter activity
SP670_RS04445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SP670_RS04450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SP670_RS04455	COG0704	Plays a role in the regulation of phosphate uptake
SP670_RS04460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SP670_RS04465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SP670_RS04470	COG3527	Alpha-acetolactate decarboxylase
SP670_RS04485	COG3842	ATPase activity
SP670_RS04495	COG1177	transmembrane transport
SP670_RS04525	COG1131	(ABC) transporter
SP670_RS04535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SP670_RS04560	COG0287	Prephenate dehydrogenase
SP670_RS04575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SP670_RS04580	COG0077	Prephenate dehydratase
SP670_RS04590	COG3475	LICD family
SP670_RS04600	COG1215	transferase activity, transferring glycosyl groups
SP670_RS04635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SP670_RS04635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SP670_RS04640	COG1132	(ABC) transporter
SP670_RS04650	COG0402	S-adenosylhomocysteine deaminase activity
SP670_RS04670	COG1737	Transcriptional regulator
SP670_RS04675	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SP670_RS04680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SP670_RS04685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SP670_RS04695	COG4409	exo-alpha-(2->6)-sialidase activity
SP670_RS04700	COG0673	inositol 2-dehydrogenase activity
SP670_RS04715	COG1269	ATP hydrolysis coupled proton transport
SP670_RS04720	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SP670_RS04805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SP670_RS04815	COG2837	iron assimilation
SP670_RS04830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SP670_RS04835	COG0716	FMN binding
SP670_RS04840	COG0077	Prephenate dehydratase
SP670_RS04840	COG1605	Chorismate mutase
SP670_RS04845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SP670_RS04850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SP670_RS04870	COG1078	dGTPase activity
SP670_RS04885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SP670_RS04900	COG1704	LemA family
SP670_RS04910	COG0488	(ABC) transporter
SP670_RS04925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SP670_RS04940	COG0505	Belongs to the CarA family
SP670_RS04950	COG3475	LICD family
SP670_RS04955	COG3475	LICD family
SP670_RS04965	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SP670_RS04970	COG1063	alcohol dehydrogenase
SP670_RS04985	COG4750	Nucleotidyl transferase
SP670_RS04990	COG0758	DNA mediated transformation
SP670_RS05005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SP670_RS05010	COG2832	Protein of unknown function (DUF454)
SP670_RS05015	COG3142	Participates in the control of copper homeostasis
SP670_RS05035	COG0473	3-isopropylmalate dehydrogenase activity
SP670_RS05045	COG0066	3-isopropylmalate dehydratase activity
SP670_RS05060	COG1401	restriction endodeoxyribonuclease activity
SP670_RS05085	COG1196	nuclear chromosome segregation
SP670_RS05090	COG0561	phosphatase activity
SP670_RS05095	COG0561	phosphatase activity
SP670_RS05100	COG0552	protein localization to endoplasmic reticulum
SP670_RS05125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SP670_RS05130	COG1126	abc transporter atp-binding protein
SP670_RS05135	COG0765	amino acid transport
SP670_RS05165	COG1827	regulation of RNA biosynthetic process
SP670_RS05175	COG4684	Psort location CytoplasmicMembrane, score
SP670_RS05180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SP670_RS05195	COG1194	a g-specific adenine glycosylase
SP670_RS05200	COG0745	RESPONSE REGULATOR receiver
SP670_RS05205	COG5002	protein histidine kinase activity
SP670_RS05210	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SP670_RS05225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SP670_RS05235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SP670_RS05240	COG3764	Sortase (surface protein transpeptidase)
SP670_RS05260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SP670_RS05295	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SP670_RS05300	COG1438	arginine binding
SP670_RS05305	COG0497	DNA recombination
SP670_RS05310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SP670_RS05365	COG3684	Belongs to the aldolase LacD family
SP670_RS05370	COG3711	transcriptional antiterminator
SP670_RS05395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SP670_RS05400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SP670_RS05405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SP670_RS05410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SP670_RS05435	COG1011	Hydrolase
SP670_RS05450	COG1051	belongs to the nudix hydrolase family
SP670_RS05455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SP670_RS05465	COG0534	Mate efflux family protein
SP670_RS05470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SP670_RS05475	COG0022	dehydrogenase e1 component
SP670_RS05480	COG0508	dehydrogenase complex catalyzes the overall conversion of
SP670_RS05485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SP670_RS05490	COG0095	Lipoate-protein ligase
SP670_RS05510	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SP670_RS05515	COG0582	viral genome integration into host DNA
SP670_RS05525	COG1396	sequence-specific DNA binding
SP670_RS05530	COG3843	relaxase mobilization nuclease domain protein
SP670_RS05620	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SP670_RS05645	COG0542	response to heat
SP670_RS05650	COG1396	sequence-specific DNA binding
SP670_RS05690	COG1396	sequence-specific DNA binding
SP670_RS05740	COG0741	lytic transglycosylase activity
SP670_RS05740	COG0791	NLP P60 protein
SP670_RS05785	COG2946	Replication initiation factor
SP670_RS05790	COG1674	ftsk spoiiie
SP670_RS05810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SP670_RS05815	COG1132	(ABC) transporter
SP670_RS05920	COG0270	DNA (cytosine-5-)-methyltransferase activity
SP670_RS05930	COG3583	domain protein
SP670_RS05930	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
SP670_RS05940	COG1074	ATP-dependent DNA helicase activity
SP670_RS05980	COG0560	Phosphoserine phosphatase
SP670_RS05985	COG0560	Phosphoserine phosphatase
SP670_RS05995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SP670_RS06005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SP670_RS06010	COG1012	belongs to the aldehyde dehydrogenase family
SP670_RS06020	COG1523	belongs to the glycosyl hydrolase 13 family
SP670_RS06040	COG0488	(ABC) transporter
SP670_RS06050	COG1307	EDD domain protein, DegV family
SP670_RS06055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SP670_RS06060	COG0196	riboflavin kinase activity
SP670_RS06110	COG0280	phosphate acetyltransferase
SP670_RS06115	COG0564	pseudouridine synthase activity
SP670_RS06125	COG2357	RelA SpoT domain protein
SP670_RS06140	COG1104	cysteine desulfurase activity
SP670_RS06160	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SP670_RS06170	COG0210	DNA helicase
SP670_RS06185	COG0024	Methionine aminopeptidase
SP670_RS06190	COG4109	DRTGG domain
SP670_RS06200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SP670_RS06225	COG0438	transferase activity, transferring glycosyl groups
SP670_RS06230	COG0438	transferase activity, transferring glycosyl groups
SP670_RS06235	COG2151	metal-sulfur cluster biosynthetic enzyme
SP670_RS06240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SP670_RS06245	COG0358	DNA primase activity
SP670_RS06265	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SP670_RS06270	COG0772	Belongs to the SEDS family
SP670_RS06305	COG0366	Alpha amylase catalytic
SP670_RS06315	COG1597	lipid kinase activity
SP670_RS06365	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SP670_RS06370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SP670_RS06390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SP670_RS06400	COG0741	lytic transglycosylase activity
SP670_RS06425	COG2890	protein-(glutamine-N5) methyltransferase activity
SP670_RS06435	COG1435	thymidine kinase activity
SP670_RS06440	COG1942	4-Oxalocrotonate Tautomerase
SP670_RS06450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SP670_RS06455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SP670_RS06465	COG4708	membrane
SP670_RS06475	COG1970	mechanosensitive ion channel activity
SP670_RS06520	COG3443	Belongs to the bacterial solute-binding protein 9 family
SP670_RS06520	COG0803	Belongs to the bacterial solute-binding protein 9 family
SP670_RS06525	COG0531	amino acid
SP670_RS06530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SP670_RS06535	COG0785	Cytochrome C biogenesis protein
SP670_RS06565	COG0584	glycerophosphoryl diester phosphodiesterase
SP670_RS06570	COG2176	DNA-directed DNA polymerase activity
SP670_RS06580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SP670_RS06590	COG0494	nUDIX hydrolase
SP670_RS06610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SP670_RS06625	COG2801	Transposase and inactivated derivatives
SP670_RS06635	COG4122	O-methyltransferase activity
SP670_RS06650	COG3615	Tellurite resistance protein tehB
SP670_RS06650	COG0500	methyltransferase
SP670_RS06660	COG0557	exoribonuclease II activity
SP670_RS06670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SP670_RS06675	COG2814	Major facilitator Superfamily
SP670_RS06680	COG0237	dephospho-CoA kinase activity
SP670_RS06685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SP670_RS06695	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SP670_RS06705	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SP670_RS06710	COG4193	domain, Protein
SP670_RS06710	COG5263	repeat protein
SP670_RS06715	COG0167	dihydroorotate dehydrogenase activity
SP670_RS06720	COG0543	2 iron, 2 sulfur cluster binding
SP670_RS06750	COG1131	(ABC) transporter
SP670_RS06760	COG0658	competence protein
SP670_RS06760	COG2333	competence protein COMEC
SP670_RS06765	COG1596	polysaccharide export
SP670_RS06765	COG1555	photosystem II stabilization
SP670_RS06770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SP670_RS06775	COG0686	Belongs to the AlaDH PNT family
SP670_RS06780	COG0686	Belongs to the AlaDH PNT family
SP670_RS06785	COG0686	Belongs to the AlaDH PNT family
SP670_RS06800	COG1702	phosphate starvation-inducible protein PhoH
SP670_RS06810	COG2996	Protein conserved in bacteria
SP670_RS06820	COG0528	UMP kinase activity
SP670_RS06865	COG0470	DNA polymerase III
SP670_RS06875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SP670_RS06890	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SP670_RS06895	COG0564	pseudouridine synthase activity
SP670_RS06900	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SP670_RS06905	COG0583	DNA-binding transcription factor activity
SP670_RS06925	COG0561	phosphatase activity
SP670_RS06930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SP670_RS06950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SP670_RS06965	COG1982	Orn Lys Arg decarboxylase major
SP670_RS06980	COG0577	efflux transmembrane transporter activity
SP670_RS06985	COG1136	(ABC) transporter
SP670_RS07005	COG2183	response to ionizing radiation
SP670_RS07015	COG0701	Predicted permease
SP670_RS07020	COG3689	TIGRFAM TIGR03943 family protein
SP670_RS07060	COG0469	pyruvate kinase activity
SP670_RS07080	COG1438	arginine binding
SP670_RS07085	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
SP670_RS07145	COG1104	cysteine desulfurase activity
SP670_RS07155	COG1674	ftsk spoiiie
SP670_RS07155	COG0697	spore germination
SP670_RS07160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SP670_RS07160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SP670_RS07160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SP670_RS07165	COG1105	Belongs to the carbohydrate kinase PfkB family
SP670_RS07170	COG1349	DNA-binding transcription factor activity
SP670_RS07180	COG0628	permease
SP670_RS07185	COG1686	Belongs to the peptidase S11 family
SP670_RS07195	COG0719	Fe-S assembly protein
SP670_RS07205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SP670_RS07210	COG0719	Fe-S assembly protein
SP670_RS07225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SP670_RS07230	COG1956	GAF domain-containing protein
SP670_RS07245	COG0539	negative regulation of cytoplasmic translation
SP670_RS07280	COG4166	transmembrane transport
SP670_RS07285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SP670_RS07290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SP670_RS07300	COG0187	DNA topoisomerase II activity
SP670_RS07315	COG2801	Transposase and inactivated derivatives
SP670_RS07330	COG1079	Belongs to the binding-protein-dependent transport system permease family
SP670_RS07335	COG4603	Belongs to the binding-protein-dependent transport system permease family
SP670_RS07340	COG3845	ABC transporter
SP670_RS07345	COG1744	ABC transporter substrate-binding protein PnrA-like
SP670_RS07350	COG0295	cytidine deaminase activity
SP670_RS07360	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SP670_RS07365	COG2813	Specifically methylates the guanine in position
SP670_RS07410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SP670_RS07430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SP670_RS07435	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SP670_RS07440	COG1126	abc transporter atp-binding protein
SP670_RS07450	COG4703	Protein of unknown function (DUF1797)
SP670_RS07455	COG0542	response to heat
SP670_RS07470	COG0494	nUDIX hydrolase
SP670_RS07480	COG2801	Transposase and inactivated derivatives
SP670_RS07505	COG3335	DDE superfamily endonuclease
SP670_RS07520	COG0187	DNA topoisomerase II activity
SP670_RS07530	COG0693	protein deglycase activity
SP670_RS07535	COG0772	Belongs to the SEDS family
SP670_RS07555	COG5002	protein histidine kinase activity
SP670_RS07560	COG0745	RESPONSE REGULATOR receiver
SP670_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
SP670_RS07600	COG4989	oxidoreductase activity
SP670_RS07620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SP670_RS07620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SP670_RS07625	COG0577	efflux transmembrane transporter activity
SP670_RS07630	COG1136	(ABC) transporter
SP670_RS07635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SP670_RS07640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SP670_RS07645	COG1268	BioY protein
SP670_RS07655	COG4443	Transcriptional Coactivator p15 (PC4)
SP670_RS07665	COG1328	CTP reductase activity
SP670_RS07665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SP670_RS07685	COG1837	Belongs to the UPF0109 family
SP670_RS07710	COG0488	(ABC) transporter
SP670_RS07725	COG4470	Protein conserved in bacteria
SP670_RS07730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SP670_RS07740	COG0167	dihydroorotate dehydrogenase activity
SP670_RS07750	COG0513	Belongs to the DEAD box helicase family
SP670_RS07760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SP670_RS07760	COG2190	(PTS) system
SP670_RS07760	COG1263	PTS System
SP670_RS07765	COG2177	Part of the ABC transporter FtsEX involved in
SP670_RS07770	COG2884	Cell division ATP-binding protein ftsE
SP670_RS07775	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SP670_RS07780	COG0617	tRNA 3'-terminal CCA addition
SP670_RS07780	COG0517	IMP dehydrogenase activity
SP670_RS07780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SP670_RS07820	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SP670_RS07825	COG2131	deaminase
SP670_RS07835	COG1307	EDD domain protein, DegV family
SP670_RS07840	COG2081	HI0933 family
SP670_RS07920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SP670_RS07945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SP670_RS07950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SP670_RS07955	COG0626	cystathionine gamma-synthase activity
SP670_RS07965	COG1132	(ABC) transporter
SP670_RS07970	COG1132	(ABC) transporter
SP670_RS07980	COG4166	transmembrane transport
SP670_RS07985	COG2244	polysaccharide biosynthetic process
SP670_RS07990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SP670_RS08015	COG2827	Endonuclease containing a URI domain
SP670_RS08020	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SP670_RS08025	COG1098	S1 RNA binding domain
SP670_RS08035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SP670_RS08040	COG0629	single-stranded DNA binding
SP670_RS08060	COG0436	Aminotransferase
SP670_RS08080	COG3022	response to hydroperoxide
SP670_RS08095	COG0242	peptide deformylase activity
SP670_RS08100	COG0625	glutathione transferase activity
SP670_RS08110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SP670_RS08120	COG0488	(ABC) transporter
SP670_RS08125	COG0617	tRNA 3'-terminal CCA addition
SP670_RS08135	COG1307	EDD domain protein, DegV family
SP670_RS08155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SP670_RS08175	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SP670_RS08185	COG0251	oxidation-reduction process
SP670_RS08205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SP670_RS08215	COG5263	repeat protein
SP670_RS08215	COG4193	domain, Protein
SP670_RS08225	COG3935	DnaD domain protein
SP670_RS08240	COG2226	methyltransferase
SP670_RS08250	COG3842	ATPase activity
SP670_RS08260	COG1335	isochorismatase
SP670_RS08270	COG0513	Belongs to the DEAD box helicase family
SP670_RS08275	COG2223	nitrite transmembrane transporter activity
SP670_RS08280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SP670_RS08285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SP670_RS08290	COG3442	glutamine amidotransferase
SP670_RS08295	COG0006	proline dipeptidase activity
SP670_RS08300	COG2801	Transposase and inactivated derivatives
SP670_RS08305	COG2801	Transposase and inactivated derivatives
SP670_RS08320	COG4720	Psort location CytoplasmicMembrane, score
SP670_RS08325	COG0351	phosphomethylpyrimidine kinase
SP670_RS08350	COG2824	Alkylphosphonate utilization operon protein PhnA
SP670_RS08370	COG0463	Glycosyl transferase, family 2
SP670_RS08375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SP670_RS08385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SP670_RS08390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SP670_RS08395	COG2384	SAM-dependent methyltransferase
SP670_RS08405	COG2801	Transposase and inactivated derivatives
SP670_RS08420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SP670_RS08425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SP670_RS08430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SP670_RS08430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SP670_RS08430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SP670_RS08435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SP670_RS08455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SP670_RS08460	COG0204	Acyl-transferase
SP670_RS08475	COG2910	NAD(P)H-binding
SP670_RS08500	COG5002	protein histidine kinase activity
SP670_RS08505	COG0745	RESPONSE REGULATOR receiver
SP670_RS08520	COG1959	2 iron, 2 sulfur cluster binding
SP670_RS08590	COG3590	peptidase
SP670_RS08605	COG0803	Belongs to the bacterial solute-binding protein 9 family
SP670_RS08610	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SP670_RS08620	COG0577	efflux transmembrane transporter activity
SP670_RS08620	COG1136	(ABC) transporter
SP670_RS08665	COG3599	regulation of cell shape
SP670_RS08685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SP670_RS08705	COG1051	belongs to the nudix hydrolase family
SP670_RS08710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SP670_RS08725	COG0768	penicillin binding
SP670_RS08740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SP670_RS08760	COG2731	YhcH YjgK YiaL family protein
SP670_RS08765	COG0395	ABC-type sugar transport system, permease component
SP670_RS08770	COG1175	transmembrane transport
SP670_RS08780	COG1263	PTS System
SP670_RS08780	COG2190	(PTS) system
SP670_RS08780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SP670_RS08790	COG0673	inositol 2-dehydrogenase activity
SP670_RS08795	COG4409	exo-alpha-(2->6)-sialidase activity
SP670_RS08810	COG4409	exo-alpha-(2->6)-sialidase activity
SP670_RS08820	COG1175	transmembrane transport
SP670_RS08825	COG1653	transport
SP670_RS08865	COG3458	cephalosporin-C deacetylase activity
SP670_RS08875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SP670_RS08890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SP670_RS08895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SP670_RS08900	COG0653	protein targeting
SP670_RS08910	COG1131	(ABC) transporter
SP670_RS08950	COG0778	Nitroreductase
SP670_RS08955	COG1484	DNA-dependent DNA replication
SP670_RS08970	COG1725	Transcriptional regulator
SP670_RS08975	COG1131	(ABC) transporter
SP670_RS08985	COG1668	transmembrane transport
SP670_RS08990	COG4152	abc transporter atp-binding protein
SP670_RS09010	COG1940	carbohydrate kinase activity
SP670_RS09015	COG1263	PTS System
SP670_RS09015	COG2190	(PTS) system
SP670_RS09015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SP670_RS09025	COG1621	beta-fructofuranosidase activity
SP670_RS09030	COG1609	Transcriptional regulator
SP670_RS09040	COG3425	synthase
SP670_RS09070	COG0515	serine threonine protein kinase
SP670_RS09070	COG2815	serine threonine protein kinase
SP670_RS09075	COG0631	protein serine/threonine phosphatase activity
SP670_RS09080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SP670_RS09080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SP670_RS09090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SP670_RS09100	COG0194	GDP metabolic process
SP670_RS09110	COG4115	mRNA cleavage
SP670_RS09125	COG2226	methyltransferase
SP670_RS09130	COG0799	negative regulation of ribosome biogenesis
SP670_RS09140	COG1713	HD superfamily hydrolase involved in NAD metabolism
SP670_RS09145	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SP670_RS09150	COG1534	Rna-binding protein
SP670_RS09155	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SP670_RS09170	COG0668	transmembrane transport
SP670_RS09195	COG3118	belongs to the thioredoxin family
SP670_RS09200	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SP670_RS09210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SP670_RS09225	COG1131	(ABC) transporter
SP670_RS09230	COG0640	Transcriptional regulator
SP670_RS09235	COG1164	Oligoendopeptidase f
SP670_RS09240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SP670_RS09300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SP670_RS09310	COG1621	beta-fructofuranosidase activity
SP670_RS09315	COG1653	transport
SP670_RS09320	COG0395	ABC-type sugar transport system, permease component
SP670_RS09325	COG4209	transmembrane transport
SP670_RS09335	COG3711	transcriptional antiterminator
SP670_RS09360	COG3237	CsbD-like
SP670_RS09375	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SP670_RS09395	COG0133	tryptophan synthase activity
SP670_RS09415	COG0512	Glutamine amidotransferase of anthranilate synthase
SP670_RS09420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SP670_RS09445	COG1285	pathogenesis
SP670_RS09450	COG1178	ABC-type Fe3 transport system permease component
SP670_RS09470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SP670_RS09475	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SP670_RS09480	COG0704	Plays a role in the regulation of phosphate uptake
SP670_RS09495	COG5434	Belongs to the glycosyl hydrolase 28 family
SP670_RS09510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SP670_RS09515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SP670_RS09520	COG1132	(ABC) transporter
SP670_RS09525	COG1132	(ABC) transporter
SP670_RS09550	COG0708	Exodeoxyribonuclease III
SP670_RS09570	COG2233	PERMEase
SP670_RS09600	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SP670_RS09605	COG1609	Transcriptional regulator
SP670_RS09610	COG1063	alcohol dehydrogenase
SP670_RS09615	COG0789	Transcriptional regulator
SP670_RS09620	COG1230	cation diffusion facilitator family transporter
SP670_RS09630	COG3201	nicotinamide mononucleotide transporter
SP670_RS09635	COG1174	glycine betaine transport
SP670_RS09660	COG1363	Peptidase, m42
SP670_RS09675	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SP670_RS09680	COG4605	iron ion homeostasis
SP670_RS09685	COG4604	ABC transporter, ATP-binding protein
SP670_RS09690	COG4607	ABC-type enterochelin transport system periplasmic component
SP670_RS09700	COG1187	pseudouridine synthase activity
SP670_RS09720	COG0517	IMP dehydrogenase activity
SP670_RS09730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SP670_RS09750	COG0366	Alpha amylase catalytic
SP670_RS09755	COG1263	PTS System
SP670_RS09755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SP670_RS09760	COG2188	Transcriptional regulator
SP670_RS09780	COG4608	Belongs to the ABC transporter superfamily
SP670_RS09785	COG0444	Belongs to the ABC transporter superfamily
SP670_RS09790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SP670_RS09795	COG0601	transmembrane transport
SP670_RS09800	COG4166	transmembrane transport
SP670_RS09810	COG0366	Alpha amylase catalytic
SP670_RS09820	COG0395	ABC-type sugar transport system, permease component
SP670_RS09825	COG1175	transmembrane transport
SP670_RS09830	COG1653	transport
SP670_RS09835	COG3345	alpha-galactosidase
SP670_RS09840	COG2207	Transcriptional regulator
SP670_RS09845	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SP670_RS09845	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SP670_RS09960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SP670_RS10000	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SP670_RS10010	COG4221	oxidoreductase activity
SP670_RS10015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SP670_RS10020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SP670_RS10055	COG1132	(ABC) transporter
SP670_RS10115	COG3842	ATPase activity
SP670_RS10120	COG1178	ABC-type Fe3 transport system permease component
SP670_RS10125	COG1285	pathogenesis
SP670_RS10190	COG5632	N-Acetylmuramoyl-L-alanine amidase
SP670_RS10190	COG5263	repeat protein
SP670_RS10210	COG1316	TRANSCRIPTIONal
SP670_RS10220	COG0802	atpase or kinase
SP670_RS10245	COG1136	(ABC) transporter
SP670_RS10245	COG0577	efflux transmembrane transporter activity
SP670_RS10275	COG1253	flavin adenine dinucleotide binding
SP670_RS10290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SP670_RS10300	COG3480	Lon protease (S16) C-terminal proteolytic domain
SP670_RS10310	COG0742	ribosomal rna small subunit methyltransferase
SP670_RS10330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SP670_RS10335	COG1254	Belongs to the acylphosphatase family
SP670_RS10345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SP670_RS10355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SP670_RS10370	COG1564	THIamine pyrophosphokinase
SP670_RS10380	COG1162	GTPase activity
SP670_RS10415	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SP670_RS10420	COG0084	hydrolase, TatD family'
SP670_RS10435	COG0436	Aminotransferase
SP670_RS10445	COG0589	response to stress
SP670_RS10450	COG0561	phosphatase activity
SP670_RS10455	COG0252	asparaginase activity
SP670_RS10465	COG1609	Transcriptional regulator
SP670_RS10470	COG2197	response regulator
SP670_RS10475	COG4585	Histidine kinase
SP670_RS10480	COG0842	Transport permease protein
SP670_RS10485	COG1131	(ABC) transporter
SP670_RS10585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SP670_RS10590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SP670_RS10595	COG0564	pseudouridine synthase activity
SP670_RS10605	COG0577	efflux transmembrane transporter activity
SP670_RS10620	COG0157	Belongs to the NadC ModD family
SP670_RS10630	COG4133	protoheme IX ABC transporter activity
SP670_RS10635	COG2188	Transcriptional regulator
SP670_RS10640	COG2723	6-phospho-beta-galactosidase activity
SP670_RS10645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SP670_RS10655	COG1447	Phosphotransferase system cellobiose-specific component IIA
SP670_RS10660	COG1454	alcohol dehydrogenase
SP670_RS10660	COG1012	belongs to the aldehyde dehydrogenase family
SP670_RS10670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SP670_RS10680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SP670_RS10700	COG3623	hexulose-6-phosphate isomerase
SP670_RS10710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SP670_RS10720	COG3037	sugar-specific permease SgaT UlaA
SP670_RS10730	COG1847	R3H domain protein
SP670_RS10735	COG0706	membrane insertase activity
SP670_RS10785	COG4537	Required for transformation and DNA binding
SP670_RS10795	COG5632	N-Acetylmuramoyl-L-alanine amidase
SP670_RS10795	COG5263	repeat protein
SP670_RS10905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SP670_RS11005	COG0629	single-stranded DNA binding
SP670_RS11040	COG3561	AntA/AntB antirepressor
SP670_RS11080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SP670_RS11085	COG1459	type II secretion system
SP670_RS11090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SP670_RS11100	COG1063	alcohol dehydrogenase
SP670_RS11125	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SP670_RS11130	COG3759	membrane
SP670_RS11145	COG0131	Imidazoleglycerol-phosphate dehydratase
SP670_RS11145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SP670_RS11150	COG0534	Mate efflux family protein
SP670_RS11250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SP670_RS11265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SP670_RS11270	COG1132	(ABC) transporter
SP670_RS11280	COG1132	(ABC) transporter
SP670_RS11290	COG1438	arginine binding
SP670_RS11310	COG0745	RESPONSE REGULATOR receiver
SP670_RS11315	COG5002	protein histidine kinase activity
SP670_RS11320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SP670_RS11325	COG0573	inorganic phosphate transmembrane transporter activity
SP670_RS11335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SP670_RS11340	COG0704	Plays a role in the regulation of phosphate uptake
SP670_RS11360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SP670_RS11370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SP670_RS11390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SP670_RS11390	COG4499	WXG100 protein secretion system (Wss), protein YukC
SP670_RS11400	COG2217	Heavy metal translocating P-type atpase
SP670_RS11410	COG2226	methyltransferase
SP670_RS11435	COG0058	SHG alpha-glucan phosphorylase activity
SP670_RS11440	COG1640	4-alpha-glucanotransferase
SP670_RS11445	COG2182	Extracellular solute-binding protein
SP670_RS11450	COG1175	transmembrane transport
SP670_RS11455	COG3833	ABC-type maltose transport systems, permease component
SP670_RS11460	COG5521	maltodextrose utilization protein MalA
SP670_RS11465	COG1609	Transcriptional regulator
SP670_RS11475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SP670_RS11510	COG1476	TRANSCRIPTIONal
SP670_RS11540	COG2151	metal-sulfur cluster biosynthetic enzyme
SP670_RS11550	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SP670_RS11555	COG3959	Transketolase, thiamine diphosphate binding domain
SP670_RS11570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SP670_RS11590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SP670_RS11630	COG0383	alpha-mannosidase activity
SP670_RS11640	COG3537	Alpha-1,2-mannosidase
SP670_RS11660	COG0549	Belongs to the carbamate kinase family
SP670_RS11665	COG1288	antiporter activity
SP670_RS11670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SP670_RS11680	COG3583	domain protein
SP670_RS11680	COG3064	Membrane
SP670_RS11680	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SP670_RS11695	COG1454	alcohol dehydrogenase
SP670_RS11705	COG0235	Class ii aldolase
SP670_RS11735	COG1175	transmembrane transport
SP670_RS11740	COG1653	transport
SP670_RS11745	COG1070	Carbohydrate kinase
SP670_RS11755	COG3443	Belongs to the bacterial solute-binding protein 9 family
SP670_RS11755	COG0803	Belongs to the bacterial solute-binding protein 9 family
SP670_RS11760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SP670_RS11765	COG1121	(ABC) transporter
SP670_RS11770	COG1846	Transcriptional regulator
SP670_RS11775	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SP670_RS11785	COG1696	Membrane protein involved in D-alanine export
SP670_RS11805	COG3344	reverse transcriptase
SP670_RS11825	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SP670_RS11830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SP670_RS11850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SP670_RS11860	COG1755	Isoprenylcysteine carboxyl methyltransferase
SP670_RS11865	COG5002	protein histidine kinase activity
SP670_RS11870	COG0745	RESPONSE REGULATOR receiver
SP670_RS11880	COG0542	response to heat
SP670_RS11885	COG4463	regulation of RNA biosynthetic process
SP670_RS11890	COG1116	anion transmembrane transporter activity
SP670_RS11895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SP670_RS11900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SP670_RS11920	COG0305	Participates in initiation and elongation during chromosome replication
SP670_RS11940	COG1040	competence protein
SP670_RS11945	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SP670_RS11950	COG1739	Uncharacterized protein family UPF0029
SP670_RS11970	COG3942	CHAP domain
SP670_RS11980	COG1792	Involved in formation and maintenance of cell shape
SP670_RS11985	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SP670_RS11990	COG1122	ATPase activity
SP670_RS11995	COG1122	ATPase activity
SP670_RS12000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SP670_RS12010	COG0612	Peptidase, M16
SP670_RS12015	COG0612	Peptidase, M16
SP670_RS12020	COG2501	S4 domain
SP670_RS12030	COG0516	GMP reductase activity
SP670_RS12030	COG0517	IMP dehydrogenase activity
SP670_RS12035	COG0180	Tryptophanyl-tRNA synthetase
SP670_RS12040	COG0488	(ABC) transporter
SP670_RS12050	COG1511	domain protein
SP670_RS12060	COG1511	domain protein
SP670_RS12105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SP670_RS12110	COG1475	DNA binding