locus-tag	class	description
HKM25_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HKM25_RS00105	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HKM25_RS00110	ENOG4105C3G	gtp-binding protein
HKM25_RS00120	ENOG4108JA2	transcriptioN-repair coupling factor
HKM25_RS00125	ENOG41082I2	s4 domain protein
HKM25_RS00145	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HKM25_RS00150	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HKM25_RS00220	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HKM25_RS00230	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HKM25_RS00245	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HKM25_RS00265	ENOG4105C2M	dna polymerase I
HKM25_RS00270	ENOG4105K4P	CoA-binding domain protein
HKM25_RS00275	ENOG4105HMI	Membrane
HKM25_RS00280	ENOG4105CHM	Aminotransferase
HKM25_RS00295	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HKM25_RS00330	ENOG4105EY8	ABC transporter
HKM25_RS00340	ENOG4108JJA	ABC, transporter
HKM25_RS00345	ENOG4107VK6	Transport protein ComB
HKM25_RS00355	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HKM25_RS00360	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HKM25_RS00370	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HKM25_RS00385	ENOG4105C12	Phosphoribosylglycinamide synthetase
HKM25_RS00390	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HKM25_RS00395	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HKM25_RS00405	ENOG4105C83	adenylosuccinate lyase
HKM25_RS00410	ENOG41069UX	Beta-N-acetyl-hexosaminidase
HKM25_RS00415	ENOG4105FDP	GntR family transcriptional regulator
HKM25_RS00425	ENOG4108IQ3	PTS system
HKM25_RS00430	ENOG4105ETZ	PTS System
HKM25_RS00435	ENOG4105F3R	pts system mannose fructose sorbose family iid
HKM25_RS00445	ENOG4105E70	isomerase
HKM25_RS00450	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HKM25_RS00455	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HKM25_RS00460	ENOG4105VPX	protein, conserved in bacteria
HKM25_RS00490	ENOG4105CZN	Potassium uptake protein
HKM25_RS00495	ENOG4107ZYR	domain protein
HKM25_RS00505	ENOG4108SHN	Glycosyl transferase, family 2
HKM25_RS00525	ENOG4108YBA	Histidine kinase
HKM25_RS00560	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HKM25_RS00595	ENOG4105U3E	Transcriptional regulator
HKM25_RS00620	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HKM25_RS00625	ENOG4105EJQ	L-serine dehydratase
HKM25_RS00660	ENOG4108HW3	(ABC) transporter
HKM25_RS00740	ENOG4105M6F	mutator MutT protein
HKM25_RS00745	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HKM25_RS00775	ENOG41072GX	Peptidase M22 Glycoprotease
HKM25_RS00810	ENOG4105JEU	Glycosyl transferase, family 2
HKM25_RS00830	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HKM25_RS00835	ENOG4105WT3	Transcriptional regulator
HKM25_RS00870	ENOG4105EAB	amino acid AbC transporter
HKM25_RS00875	ENOG4105D01	(LipO)protein
HKM25_RS00880	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HKM25_RS00885	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HKM25_RS00905	ENOG4105C2F	Histidine kinase
HKM25_RS00910	ENOG4107VQW	regulatoR
HKM25_RS00920	ENOG4105MTF	NrdI protein
HKM25_RS00925	ENOG4105K3M	)-transporter
HKM25_RS00950	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HKM25_RS00955	ENOG4108R6K	riboflavin synthase, subunit alpha
HKM25_RS00960	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HKM25_RS00970	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HKM25_RS00995	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HKM25_RS01000	ENOG4105DC7	peptidase M24
HKM25_RS01005	ENOG410888K	transcriptional regulator, Spx
HKM25_RS01030	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HKM25_RS01040	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HKM25_RS01055	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HKM25_RS01070	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HKM25_RS01105	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HKM25_RS01130	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HKM25_RS01170	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HKM25_RS01185	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HKM25_RS01195	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HKM25_RS01210	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HKM25_RS01215	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HKM25_RS01225	ENOG4105VUC	UPF0237 protein
HKM25_RS01260	ENOG4105F1A	Pyruvate formate-lyase
HKM25_RS01265	ENOG4105N2W	Transcriptional regulator
HKM25_RS01270	ENOG4105DKT	Transcriptional regulator
HKM25_RS01275	ENOG4105VCP	PTS System
HKM25_RS01280	ENOG4105VZJ	PTS System
HKM25_RS01285	ENOG4105CK1	PTS System
HKM25_RS01335	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HKM25_RS01340	ENOG4105KNE	Phosphatidate cytidylyltransferase
HKM25_RS01345	ENOG4105DZP	Membrane-associated zinc metalloprotease
HKM25_RS01355	ENOG4105CS2	ec 3.2.1.21
HKM25_RS01360	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HKM25_RS01375	ENOG4108IUM	Glycogen debranching enzyme
HKM25_RS01395	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HKM25_RS01415	ENOG4105C88	aminopeptidase
HKM25_RS01420	ENOG4107BMA	Transglycosylase associated protein
HKM25_RS01430	ENOG4105CTZ	aminopeptidase c
HKM25_RS01435	ENOG4105F3R	pts system mannose fructose sorbose family iid
HKM25_RS01440	ENOG4105ETZ	PTS System
HKM25_RS01455	ENOG4105DQF	Hydrolase
HKM25_RS01460	ENOG4105C7N	Xanthine uracil vitamin C permease
HKM25_RS01470	ENOG4105EEI	dihydropteroate synthase
HKM25_RS01475	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HKM25_RS01485	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKM25_RS01495	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HKM25_RS01545	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HKM25_RS01550	ENOG4105K63	Thioredoxin
HKM25_RS01555	ENOG4105C3M	thioredoxin reductase
HKM25_RS01565	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HKM25_RS01610	ENOG4105CS2	ec 3.2.1.21
HKM25_RS01615	ENOG4105W3H	MtN3 and saliva related transmembrane protein
HKM25_RS01625	ENOG4105EMD	TRANSCRIPTIONal
HKM25_RS01640	ENOG4105CK1	PTS System
HKM25_RS01655	ENOG4108V06	Glutathione peroxidase
HKM25_RS01660	ENOG4106AM8	polysaccharide lyase family 8
HKM25_RS01695	ENOG4105EP8	Glycosyl Hydrolase Family 88
HKM25_RS01700	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
HKM25_RS01705	ENOG4105ETZ	PTS System
HKM25_RS01710	ENOG4105F3R	pts system mannose fructose sorbose family iid
HKM25_RS01725	ENOG4108M60	Transcriptional regulator
HKM25_RS01755	ENOG41068DC	Essential cell division protein (By similarity)
HKM25_RS01760	ENOG4105CJN	penicillin-binding protein
HKM25_RS01790	ENOG4105CG3	alpha amylase, catalytic region
HKM25_RS01795	ENOG4105DIB	Oligopeptide-binding protein
HKM25_RS01810	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
HKM25_RS01815	ENOG4105HTX	biosynthesis protein
HKM25_RS01820	ENOG4105D75	Capsular exopolysaccharide family
HKM25_RS01830	ENOG4105X1N	Glycosyl transferase family 8
HKM25_RS01835	ENOG4105KPE	licD family
HKM25_RS01845	ENOG4105K64	Glycosyl transferase, family 2
HKM25_RS01860	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HKM25_RS01870	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HKM25_RS01875	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HKM25_RS01895	ENOG4105DIB	Oligopeptide-binding protein
HKM25_RS01900	ENOG4105ESP	cell wall surface anchor family protein
HKM25_RS01905	ENOG4105BZ4	penicillin-binding protein
HKM25_RS01930	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HKM25_RS01935	ENOG41070VT	
HKM25_RS01940	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HKM25_RS01945	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKM25_RS02005	ENOG4105ENE	Histidine kinase
HKM25_RS02010	ENOG4105WH1	Two component transcriptional regulator luxr family
HKM25_RS02040	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HKM25_RS02045	ENOG4105C7H	Helicase, RecD TraA family
HKM25_RS02050	ENOG4105C3F	Signal peptidase i
HKM25_RS02075	ENOG4105BZG	amino acid carrier protein
HKM25_RS02100	ENOG4105CFH	Aspartokinase
HKM25_RS02105	ENOG4105CGU	Enoyl-CoA hydratase
HKM25_RS02110	ENOG4105NTK	Transcriptional repressor Mpra
HKM25_RS02125	ENOG4105EA8	2-Nitropropane dioxygenase
HKM25_RS02130	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HKM25_RS02135	ENOG4105CHR	reductase
HKM25_RS02155	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HKM25_RS02160	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HKM25_RS02195	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HKM25_RS02210	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HKM25_RS02220	ENOG4105VB9	50S ribosomal protein l28
HKM25_RS02230	ENOG4105DP4	dak2 domain fusion protein ylov
HKM25_RS02245	ENOG4108ZP8	Acetolactate synthase small subunit
HKM25_RS02265	ENOG4105C7B	Threonine dehydratase
HKM25_RS02280	ENOG4105E5Q	amino acid AbC transporter
HKM25_RS02300	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HKM25_RS02305	ENOG4105C6N	Formate acetyltransferase
HKM25_RS02330	ENOG4105E2R	ROK family
HKM25_RS02335	ENOG4105CK1	PTS System
HKM25_RS02345	ENOG4105VCP	PTS System
HKM25_RS02350	ENOG4105CS2	ec 3.2.1.21
HKM25_RS02355	ENOG4105CK1	PTS System
HKM25_RS02360	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HKM25_RS02365	ENOG4105C1A	potassium transporter peripheral membrane
HKM25_RS02385	ENOG4108JJB	ABC transporter
HKM25_RS02400	ENOG4108SAX	Membrane
HKM25_RS02405	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HKM25_RS02415	ENOG4108Z7F	N-acetyltransferase
HKM25_RS02425	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HKM25_RS02435	ENOG4108478	ec 3.2.1.18
HKM25_RS02450	ENOG4105KV4	Transcriptional regulator
HKM25_RS02455	ENOG4105C5F	glutamine synthetase
HKM25_RS02475	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HKM25_RS02500	ENOG4108F3G	Type I restriction-modification system, R subunit
HKM25_RS02515	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKM25_RS02530	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HKM25_RS02545	ENOG4105K59	histidine triad (HIT) protein
HKM25_RS02585	ENOG4107VK6	Transport protein ComB
HKM25_RS02590	ENOG4108JJA	ABC, transporter
HKM25_RS02640	ENOG4108TYN	CAAX amino terminal protease family protein
HKM25_RS02660	ENOG4105CHV	Transcription elongation factor NusA
HKM25_RS02665	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
HKM25_RS02725	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HKM25_RS02735	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HKM25_RS02770	ENOG4105CID	antiterminator
HKM25_RS02775	ENOG4105C5Y	PTS System
HKM25_RS02790	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
HKM25_RS02795	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HKM25_RS02810	ENOG4105KDP	XRE family
HKM25_RS02815	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HKM25_RS02820	ENOG4105SYT	Methylenetetrahydrofolate reductase
HKM25_RS02825	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HKM25_RS02830	ENOG4105D7W	serine acetyltransferase
HKM25_RS02840	ENOG4105C8N	cysteinyl-tRNA synthetase
HKM25_RS02845	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKM25_RS02870	ENOG4107WD8	ABC transporter, permease
HKM25_RS02880	ENOG4107WD8	ABC transporter, permease
HKM25_RS02885	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HKM25_RS02890	ENOG4105BZU	Histidine kinase
HKM25_RS02895	ENOG4105D2N	Aldolase
HKM25_RS02905	ENOG4105DRP	amino acid AbC transporter
HKM25_RS02910	ENOG4105EAD	ABC transporter
HKM25_RS02915	ENOG4107RP9	extracellular solute-binding protein, family 3
HKM25_RS02925	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HKM25_RS02935	ENOG4107UWA	esterase
HKM25_RS02980	ENOG4108RG0	uracil-dna glycosylase
HKM25_RS02990	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HKM25_RS02995	ENOG4105DER	m42 family
HKM25_RS03035	ENOG4108IUW	ABC transporter
HKM25_RS03065	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
HKM25_RS03080	ENOG4105DT3	PTS system, galactitol-specific IIc component
HKM25_RS03090	ENOG4105CNT	hydrolase family 2
HKM25_RS03120	ENOG4105EEQ	Na H antiporter
HKM25_RS03130	ENOG4107QIV	Cytochrome c biogenesis protein
HKM25_RS03135	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKM25_RS03140	ENOG4105E0X	reductase
HKM25_RS03145	ENOG4105EQD	regulatoR
HKM25_RS03150	ENOG4105C2F	Histidine kinase
HKM25_RS03155	ENOG4108UIC	UPF0340 protein
HKM25_RS03165	ENOG4105CRQ	synthase (Component I)
HKM25_RS03180	ENOG4105DKQ	ROK family
HKM25_RS03195	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HKM25_RS03200	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HKM25_RS03205	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
HKM25_RS03215	ENOG4108IXY	short-chain dehydrogenase reductase
HKM25_RS03230	ENOG4105WZW	rhodanese family
HKM25_RS03250	ENOG4105CI3	gtp-binding protein typa
HKM25_RS03280	ENOG4105C19	ABC transporter
HKM25_RS03285	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HKM25_RS03295	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
HKM25_RS03305	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HKM25_RS03330	ENOG4105CJ1	ABC, transporter
HKM25_RS03335	ENOG4105CT1	(ABC) transporter
HKM25_RS03345	ENOG4105E5Q	amino acid AbC transporter
HKM25_RS03350	ENOG4105E5Q	amino acid AbC transporter
HKM25_RS03380	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HKM25_RS03390	ENOG4108JJB	ABC transporter
HKM25_RS03400	ENOG4105ETU	transcriptional activator (TenA
HKM25_RS03415	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HKM25_RS03425	ENOG4105NA0	Transcriptional regulator
HKM25_RS03435	ENOG4105C59	p-type ATPase
HKM25_RS03440	ENOG4105C7K	acetolactate synthase
HKM25_RS03455	ENOG4105CS2	ec 3.2.1.21
HKM25_RS03460	ENOG4105DG6	mannose-6-phosphate isomerase
HKM25_RS03465	ENOG4105C8J	)-transporter
HKM25_RS03470	ENOG4107TXC	Transcriptional regulator
HKM25_RS03495	ENOG4108S8M	degv family
HKM25_RS03505	ENOG4108UK2	deaminase
HKM25_RS03510	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HKM25_RS03530	ENOG4105C32	Amino acid ABC transporter (Permease)
HKM25_RS03535	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HKM25_RS03540	ENOG4105C0Z	ABC transporter
HKM25_RS03545	ENOG4108IV0	ABC, transporter
HKM25_RS03560	ENOG4105CAK	Cell division ATP-binding protein ftsE
HKM25_RS03565	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HKM25_RS03570	ENOG4105CI1	PTS System
HKM25_RS03580	ENOG4105C1J	atp-dependent rna helicase
HKM25_RS03590	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HKM25_RS03600	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HKM25_RS03605	ENOG4105MMD	transcriptional regulator
HKM25_RS03620	ENOG4105C5H	ABC transporter
HKM25_RS03645	ENOG4105VB6	UPF0109 protein
HKM25_RS03665	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HKM25_RS03675	ENOG4105VEM	Conserved domain protein
HKM25_RS03685	ENOG4105VKD	bioY protein
HKM25_RS03690	ENOG4105DC8	reductase
HKM25_RS03695	ENOG4107X8C	Efflux transporter RND family MFP subunit
HKM25_RS03700	ENOG4105C19	ABC transporter
HKM25_RS03705	ENOG4107RBB	ABC transporter, permease
HKM25_RS03710	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HKM25_RS03730	ENOG4107RGM	aldo keto reductase
HKM25_RS03740	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HKM25_RS03770	ENOG4108STX	response regulator
HKM25_RS03775	ENOG4105US7	Histidine kinase
HKM25_RS03800	ENOG4108Z0Z	intracellular protease Pfpi family
HKM25_RS03810	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKM25_RS03830	ENOG4105M6F	mutator MutT protein
HKM25_RS03840	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HKM25_RS03845	ENOG4107IN1	Protein of unknown function (DUF1797)
HKM25_RS03850	ENOG4105E5Q	amino acid AbC transporter
HKM25_RS03855	ENOG4105CDA	abc transporter atp-binding protein
HKM25_RS03860	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HKM25_RS03865	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HKM25_RS03885	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
HKM25_RS03895	ENOG4105E5P	Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation
HKM25_RS03910	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HKM25_RS03925	ENOG4107Y49	methyltransferase
HKM25_RS03930	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HKM25_RS03940	ENOG4105KG3	cytidine deaminase
HKM25_RS03945	ENOG4105DIH	basic membrane
HKM25_RS03950	ENOG4108JQ9	ABC transporter
HKM25_RS03955	ENOG4105UIB	(ABC) transporter
HKM25_RS03975	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKM25_RS03980	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKM25_RS03985	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HKM25_RS03990	ENOG4105DIB	Oligopeptide-binding protein
HKM25_RS04025	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HKM25_RS04035	ENOG4108ZGC	gaf domain protein
HKM25_RS04040	ENOG4105C6E	dna polymerase iii
HKM25_RS04055	ENOG4105JRK	feS assembly protein SufD
HKM25_RS04065	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HKM25_RS04070	ENOG4105DIW	FeS assembly protein SUFB
HKM25_RS04080	ENOG4105C02	permease
HKM25_RS04110	ENOG4105N2W	Transcriptional regulator
HKM25_RS04115	ENOG4105DE4	1-phosphofructokinase
HKM25_RS04120	ENOG4105DM4	PTS System
HKM25_RS04125	ENOG4105CNU	cell division protein FtsK
HKM25_RS04135	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HKM25_RS04145	ENOG4105C3J	Cysteine desulfurase
HKM25_RS04170	ENOG4105CVR	type I restriction-modification system
HKM25_RS04200	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
HKM25_RS04205	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HKM25_RS04225	ENOG4105CA9	Pyruvate kinase
HKM25_RS04265	ENOG4108NNR	transporter substrate-binding protein
HKM25_RS04270	ENOG4108PJD	permease
HKM25_RS04275	ENOG4105TWJ	Domain of unknown function (DUF1919)
HKM25_RS04300	ENOG4105C19	ABC transporter
HKM25_RS04320	ENOG4105CXN	decarboxylase
HKM25_RS04330	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HKM25_RS04355	ENOG410667J	hydrolase
HKM25_RS04380	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HKM25_RS04385	ENOG4105C34	Pseudouridine synthase
HKM25_RS04405	ENOG4105II7	pyrroline-5-carboxylate reductase
HKM25_RS04415	ENOG4105FA2	dna polymerase iii
HKM25_RS04425	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HKM25_RS04465	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HKM25_RS04475	ENOG4105QNR	S1 RNA binding domain protein
HKM25_RS04485	ENOG4105C9A	Phoh family
HKM25_RS04510	ENOG41068WN	
HKM25_RS04515	ENOG4105KQC	Competence protein
HKM25_RS04520	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HKM25_RS04530	ENOG4105DA5	(ABC) transporter
HKM25_RS04560	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
HKM25_RS04565	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HKM25_RS04570	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
HKM25_RS04585	ENOG4107YR5	Diacylglycerol kinase
HKM25_RS04595	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HKM25_RS04600	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HKM25_RS04605	ENOG4105C6X	Major Facilitator
HKM25_RS04610	ENOG410861F	50S ribosomal protein L33
HKM25_RS04620	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HKM25_RS04630	ENOG41088CC	tellurite resistance protein tehB
HKM25_RS04670	ENOG4108Z66	YbaK ebsC protein
HKM25_RS04690	ENOG4108YZ4	nudix hydrolase
HKM25_RS04700	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HKM25_RS04710	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HKM25_RS04715	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HKM25_RS04735	ENOG4107QIV	Cytochrome c biogenesis protein
HKM25_RS04740	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKM25_RS04745	ENOG4105CUB	amino acid
HKM25_RS04750	ENOG4105DSE	periplasmic solute binding protein
HKM25_RS04785	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HKM25_RS04790	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HKM25_RS04795	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HKM25_RS04805	ENOG410807C	QueT transporter
HKM25_RS04815	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HKM25_RS04830	ENOG41069HH	4-oxalocrotonate tautomerase
HKM25_RS04835	ENOG4107104	thymidine kinase
HKM25_RS04870	ENOG41065S2	pneumococcal vaccine antigen
HKM25_RS04880	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HKM25_RS04900	ENOG4105DQ5	transport system permease protein
HKM25_RS04905	ENOG4105TVJ	transport system, permease
HKM25_RS04910	ENOG4105E0A	ABC, transporter
HKM25_RS04940	ENOG4108C33	Resolvase
HKM25_RS04965	ENOG4106ZEE	Diacylglycerol kinase
HKM25_RS04985	ENOG4108WZA	zeta toxin
HKM25_RS04990	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HKM25_RS05010	ENOG4105MU5	relaxase mobilization nuclease domain protein
HKM25_RS05060	ENOG4105CEY	Amp-dependent synthetase and ligase
HKM25_RS05105	ENOG4105CNI	cell division protein FtsW
HKM25_RS05110	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HKM25_RS05125	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HKM25_RS05130	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HKM25_RS05135	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HKM25_RS05140	ENOG4105VG1	fes assembly suf system protein
HKM25_RS05145	ENOG4105W2C	Glycosyl transferase
HKM25_RS05150	ENOG4105BZF	Glycosyl transferase (Group 1
HKM25_RS05190	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HKM25_RS05205	ENOG4105C4R	Atp-dependent dna helicase
HKM25_RS05235	ENOG4105C3J	Cysteine desulfurase
HKM25_RS05240	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HKM25_RS05260	ENOG4105EMS	pseudouridine synthase
HKM25_RS05265	ENOG4108IJ2	phosphate acetyltransferase
HKM25_RS05305	ENOG4105DTN	riboflavin biosynthesis protein ribF
HKM25_RS05310	ENOG4108JYZ	YitT family
HKM25_RS05315	ENOG4108RCR	degv family
HKM25_RS05320	ENOG4105K70	DNA-binding protein
HKM25_RS05325	ENOG4105C5H	ABC transporter
HKM25_RS05345	ENOG4108IUM	Glycogen debranching enzyme
HKM25_RS05350	ENOG4105C26	Dehydrogenase
HKM25_RS05355	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HKM25_RS05375	ENOG4105EAC	phosphoserine phosphatase
HKM25_RS05380	ENOG4105EAC	phosphoserine phosphatase
HKM25_RS05440	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HKM25_RS05445	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HKM25_RS05460	ENOG4105DF9	Lipoate-protein, ligase
HKM25_RS05470	ENOG4105C7S	Dehydrogenase
HKM25_RS05475	ENOG4105CPP	Dehydrogenase, E1 component
HKM25_RS05480	ENOG4107RUY	(E1 component), alpha subunit
HKM25_RS05485	ENOG4107QMU	Mate efflux family protein
HKM25_RS05495	ENOG4105CD3	dihydroorotase
HKM25_RS05500	ENOG4108Z4K	mutator MutT protein
HKM25_RS05525	ENOG4105VDH	Dihydroxyacetone kinase
HKM25_RS05540	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HKM25_RS05545	ENOG4105KRI	phosphocarrier protein (HPr
HKM25_RS05550	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
HKM25_RS05555	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HKM25_RS05560	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HKM25_RS05590	ENOG4105CID	antiterminator
HKM25_RS05595	ENOG4105D2M	Aldolase
HKM25_RS05645	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HKM25_RS05650	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HKM25_RS05655	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HKM25_RS05660	ENOG4105DX0	Hemolysin A
HKM25_RS05690	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HKM25_RS05715	ENOG4108Z6X	(sortase) family
HKM25_RS05720	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKM25_RS05750	ENOG4105Q2H	domain protein
HKM25_RS05755	ENOG4105BZU	Histidine kinase
HKM25_RS05760	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKM25_RS05765	ENOG4105CEN	a g-specific adenine glycosylase
HKM25_RS05780	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HKM25_RS05785	ENOG4105FH5	Membrane
HKM25_RS05790	ENOG4105RNB	
HKM25_RS05825	ENOG4105E5Q	amino acid AbC transporter
HKM25_RS05830	ENOG4105CDA	abc transporter atp-binding protein
HKM25_RS05835	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HKM25_RS05840	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKM25_RS05845	ENOG410667J	hydrolase
HKM25_RS05850	ENOG4108HCJ	Hydrolase
HKM25_RS05855	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HKM25_RS05880	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HKM25_RS05890	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HKM25_RS05900	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HKM25_RS05915	ENOG4106N3A	copper homeostasis protein cutc
HKM25_RS05920	ENOG4105WD1	Membrane
HKM25_RS05925	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HKM25_RS05935	ENOG4105C79	DNA protecting protein DprA
HKM25_RS05950	ENOG4108KN0	Choline kinase
HKM25_RS05955	ENOG4105EJJ	Dehydrogenase
HKM25_RS05960	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HKM25_RS05970	ENOG4105KPE	licD family
HKM25_RS05975	ENOG4105KPE	licD family
HKM25_RS05985	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HKM25_RS06000	ENOG4105CSM	endonuclease III
HKM25_RS06015	ENOG4105C5H	ABC transporter
HKM25_RS06025	ENOG4108V0P	LemA family
HKM25_RS06040	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKM25_RS06055	ENOG4105DCI	Phosphohydrolase
HKM25_RS06075	ENOG4106A8V	Protein CrcB homolog
HKM25_RS06080	ENOG4106A8V	Protein CrcB homolog
HKM25_RS06085	ENOG4105CQC	Prephenate dehydratase
HKM25_RS06095	ENOG4105SFS	phosphoesterase RecJ domain protein
HKM25_RS06120	ENOG4107R37	Glutamate dehydrogenase
HKM25_RS06160	ENOG4105CBX	hi0933 family
HKM25_RS06175	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HKM25_RS06185	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HKM25_RS06215	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HKM25_RS06225	ENOG4105CUG	Oligopeptidase b
HKM25_RS06230	ENOG4105CJA	serine threonine protein kinase
HKM25_RS06280	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HKM25_RS06295	ENOG4105BZ1	(ABC) transporter
HKM25_RS06300	ENOG4105E0X	reductase
HKM25_RS06315	ENOG4105D6E	homoserine dehydrogenase
HKM25_RS06340	ENOG4107XU6	Glycosyl transferase (Group 1
HKM25_RS06345	ENOG4105KPE	licD family
HKM25_RS06350	ENOG4108RCF	TRANSCRIPTIONal
HKM25_RS06355	ENOG4105CQC	Prephenate dehydratase
HKM25_RS06360	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HKM25_RS06375	ENOG4105EVN	Prephenate dehydrogenase
HKM25_RS06400	ENOG4105DR4	Methyltransferase
HKM25_RS06435	ENOG4108HM4	ABC transporter
HKM25_RS06450	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HKM25_RS06465	ENOG4107FQX	Alpha-acetolactate decarboxylase
HKM25_RS06475	ENOG4107R0W	ABC transporter
HKM25_RS06485	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HKM25_RS06490	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HKM25_RS06495	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HKM25_RS06500	ENOG4105E2Z	phosphate ABC transporter (Permease
HKM25_RS06505	ENOG4105C8U	phosphate abc transporter
HKM25_RS06510	ENOG4105CVA	phosphate
HKM25_RS06515	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HKM25_RS06520	ENOG4105ECY	inositol monophosphatase
HKM25_RS06530	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HKM25_RS06540	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HKM25_RS06550	ENOG4105CSA	Coproporphyrinogen iii oxidase
HKM25_RS06605	ENOG4105D9U	N-acetyltransferase
HKM25_RS06615	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HKM25_RS06625	ENOG41067QW	Transcriptional regulator
HKM25_RS06640	ENOG4105CJ1	ABC, transporter
HKM25_RS06655	ENOG4105CFP	Peptidase U32
HKM25_RS06680	ENOG4105BZ1	(ABC) transporter
HKM25_RS06685	ENOG4105BZ1	(ABC) transporter
HKM25_RS06700	ENOG4108JJB	ABC transporter
HKM25_RS06740	ENOG4108UZ3	Transporter
HKM25_RS06745	ENOG4107QK9	Beta-lactamase
HKM25_RS06760	ENOG4108HCJ	Hydrolase
HKM25_RS06780	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HKM25_RS06785	ENOG4105C3M	thioredoxin reductase
HKM25_RS06795	ENOG4105CDA	abc transporter atp-binding protein
HKM25_RS06800	ENOG4105E5Q	amino acid AbC transporter
HKM25_RS06805	ENOG41080E8	Transcriptional regulator, Spx MgsR family
HKM25_RS06810	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HKM25_RS06825	ENOG4108UT2	hemolysin iii
HKM25_RS06855	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HKM25_RS06885	ENOG4108ZJ4	polysaccharide deacetylase
HKM25_RS06915	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HKM25_RS06960	ENOG4106TNF	Periplasmic binding protein
HKM25_RS06965	ENOG4105CDA	abc transporter atp-binding protein
HKM25_RS06970	ENOG4105E5Q	amino acid AbC transporter
HKM25_RS06975	ENOG41068YB	TPR repeat-containing protein
HKM25_RS06985	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HKM25_RS07040	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HKM25_RS07070	ENOG4105C0D	helicase
HKM25_RS07075	ENOG4105C87	Aminotransferase class I and II
HKM25_RS07080	ENOG4105C28	cystathionine
HKM25_RS07085	ENOG4105BZ1	(ABC) transporter
HKM25_RS07090	ENOG4105DIB	Oligopeptide-binding protein
HKM25_RS07100	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HKM25_RS07125	ENOG4105VC4	domain protein
HKM25_RS07130	ENOG41060K3	Methyltransferase
HKM25_RS07135	ENOG41060GV	RNA binding s1 domain protein
HKM25_RS07145	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HKM25_RS07150	ENOG4108UUM	single-stranded DNA-binding protein
HKM25_RS07160	ENOG4105C5S	asparaginyl-tRNA synthetase
HKM25_RS07170	ENOG4105CHM	Aminotransferase
HKM25_RS07210	ENOG4107YDN	peptide deformylase
HKM25_RS07230	ENOG4105C5H	ABC transporter
HKM25_RS07245	ENOG4105EPR	degv family
HKM25_RS07265	ENOG4105C8B	TIGR00159 family
HKM25_RS07275	ENOG4105WWX	n-acetylmuramoyl-l-alanine amidase
HKM25_RS07380	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HKM25_RS07570	ENOG4105WWX	n-acetylmuramoyl-l-alanine amidase
HKM25_RS07675	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HKM25_RS07725	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HKM25_RS07915	ENOG4105CIE	May be required for sporulation (By similarity)
HKM25_RS07920	ENOG4105CHW	UPF0052 protein
HKM25_RS07930	ENOG4105KME	endoribonuclease L-psp
HKM25_RS07950	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HKM25_RS07960	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
HKM25_RS07985	ENOG4105DVA	methyltransferase
HKM25_RS07995	ENOG4108IJ9	(ABC) transporter
HKM25_RS08015	ENOG4105C1J	atp-dependent rna helicase
HKM25_RS08025	ENOG4107QN2	dihydrolipoyl dehydrogenase
HKM25_RS08030	ENOG4105DMS	mur ligase
HKM25_RS08035	ENOG4105F1K	Glutamine amidotransferase
HKM25_RS08040	ENOG4105DC7	peptidase M24
HKM25_RS08055	ENOG4105PUK	Membrane
HKM25_RS08060	ENOG4105DWF	phosphomethylpyrimidine kinase
HKM25_RS08080	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HKM25_RS08100	ENOG4105CKK	Glycosyl transferase, family 2
HKM25_RS08105	ENOG4105CMR	udp-glucose 4-epimerase
HKM25_RS08115	ENOG4107VFR	oxidoreductase
HKM25_RS08120	ENOG4105EGD	dinuclear metal center protein, YbgI family
HKM25_RS08130	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HKM25_RS08135	ENOG4105F6E	Acyl-transferase
HKM25_RS08155	ENOG4108RYK	Nad-dependent epimerase dehydratase
HKM25_RS08175	ENOG4105EWM	Histidine kinase
HKM25_RS08180	ENOG4105CJZ	response regulator
HKM25_RS08195	ENOG4108Z40	Transcriptional regulator
HKM25_RS08240	ENOG4105C9K	Endothelin-converting enzyme 1
HKM25_RS08245	ENOG4105DIK	(ABC) transporter
HKM25_RS08250	ENOG4105CC5	ABC transporter
HKM25_RS08255	ENOG4105DSE	periplasmic solute binding protein
HKM25_RS08260	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HKM25_RS08270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HKM25_RS08300	ENOG4105MMF	Cell division protein DIVIVA
HKM25_RS08320	ENOG4105DFA	alanine racemase domain protein
HKM25_RS08340	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HKM25_RS08355	ENOG4107RF6	penicillin-binding protein
HKM25_RS08385	ENOG4108R66	Conserved Protein
HKM25_RS08390	ENOG4105DRS	transport system, permease
HKM25_RS08395	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HKM25_RS08415	ENOG4105CK5	oxidoreductase
HKM25_RS08430	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HKM25_RS08435	ENOG4105XN3	extracellular solute-binding protein family 1
HKM25_RS08445	ENOG4108478	ec 3.2.1.18
HKM25_RS08460	ENOG4105I82	acetyl xylan esterase
HKM25_RS08465	ENOG4105CB5	ATP-dependent DNA helicase recG
HKM25_RS08480	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HKM25_RS08485	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HKM25_RS08500	ENOG4105DA5	(ABC) transporter
HKM25_RS08560	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
HKM25_RS08565	ENOG4105CZV	ABC transporter
HKM25_RS08575	ENOG4105RHA	ABC transporter, permease
HKM25_RS08580	ENOG4108IUX	(ABC) transporter
HKM25_RS08600	ENOG4105EVU	fructokinase
HKM25_RS08605	ENOG4105C5Y	PTS System
HKM25_RS08615	ENOG4105ETE	Transcriptional regulator (LacI family
HKM25_RS08625	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
HKM25_RS08650	ENOG4105D9P	serine threonine protein kinase
HKM25_RS08655	ENOG4108ZF3	Phosphatase
HKM25_RS08660	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HKM25_RS08670	ENOG4105C25	Primosomal protein n'
HKM25_RS08680	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HKM25_RS08700	ENOG4105DXX	methyltransferase
HKM25_RS08705	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HKM25_RS08715	ENOG4108WF2	Metal Dependent Phosphohydrolase
HKM25_RS08720	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HKM25_RS08725	ENOG410812S	Rna-binding protein
HKM25_RS08730	ENOG4105CQW	ribosome biogenesis GTPase YqeH
HKM25_RS08745	ENOG4105D8X	mechanosensitive ion channel
HKM25_RS08785	ENOG4108MGR	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity)
HKM25_RS08895	ENOG4105K63	Thioredoxin
HKM25_RS08900	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HKM25_RS08910	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HKM25_RS08920	ENOG4105DPN	Oligoendopeptidase f
HKM25_RS08925	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HKM25_RS08935	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HKM25_RS08970	ENOG4105D1H	recombination factor protein RarA
HKM25_RS08980	ENOG4107R3K	hydrolase
HKM25_RS08985	ENOG4108JP0	extracellular solute-binding protein family 1
HKM25_RS08990	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HKM25_RS09010	ENOG4107BMA	Transglycosylase associated protein
HKM25_RS09030	ENOG41061M1	UPF0337 protein
HKM25_RS09075	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HKM25_RS09090	ENOG4105DDQ	anthranilate synthase
HKM25_RS09095	ENOG4105CRQ	synthase (Component I)
HKM25_RS09105	ENOG4105ETE	Transcriptional regulator (LacI family
HKM25_RS09115	ENOG4105KT7	mgtC SapB transporter
HKM25_RS09125	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HKM25_RS09140	ENOG4105CMR	udp-glucose 4-epimerase
HKM25_RS09145	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
HKM25_RS09150	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HKM25_RS09165	ENOG41067D4	cell wall surface anchor family protein
HKM25_RS09170	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HKM25_RS09175	ENOG4105D3Q	Sugar transferase
HKM25_RS09180	ENOG4105BZ1	(ABC) transporter
HKM25_RS09185	ENOG4105BZ1	(ABC) transporter
HKM25_RS09200	ENOG4105CGK	Exodeoxyribonuclease III
HKM25_RS09220	ENOG4105C2W	permease
HKM25_RS09230	ENOG4108HED	Type II restriction
HKM25_RS09245	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HKM25_RS09250	ENOG4105CQ4	Transcriptional regulator
HKM25_RS09255	ENOG4105CPQ	Dehydrogenase
HKM25_RS09260	ENOG4105VUF	Transcriptional regulator
HKM25_RS09265	ENOG4105PGM	cation diffusion facilitator family transporter
HKM25_RS09280	ENOG4105E90	ABC transporter
HKM25_RS09305	ENOG4105CN9	Peptidase m42 family protein
HKM25_RS09315	ENOG4105DHS	permease protein
HKM25_RS09320	ENOG4105CM4	permease protein
HKM25_RS09325	ENOG4108IPW	abc transporter atp-binding protein
HKM25_RS09340	ENOG4105FE9	pseudouridine synthase
HKM25_RS09370	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HKM25_RS09385	ENOG4105CG3	alpha amylase, catalytic region
HKM25_RS09390	ENOG4105C5Y	PTS System
HKM25_RS09395	ENOG4107414	GntR family transcriptional regulator
HKM25_RS09405	ENOG4108JQ7	(ABC) transporter
HKM25_RS09410	ENOG4105C3U	ABC transporter
HKM25_RS09415	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HKM25_RS09420	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HKM25_RS09425	ENOG4105DIB	Oligopeptide-binding protein
HKM25_RS09435	ENOG4107RK0	Sucrose phosphorylase
HKM25_RS09450	ENOG4107YY3	extracellular solute-binding protein family 1
HKM25_RS09455	ENOG4105DME	alpha-galactosidase
HKM25_RS09460	ENOG4108R6W	Transcriptional regulator, ARAC family
HKM25_RS09465	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HKM25_RS09580	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HKM25_RS09585	ENOG4108R0M	Aminoglycoside
HKM25_RS09610	ENOG4107UWY	Methyltransferase
HKM25_RS09635	ENOG4105EMU	Dehydrogenase
HKM25_RS09640	ENOG4108VDD	TRNA binding domain protein
HKM25_RS09700	ENOG4105E5P	Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation
HKM25_RS09755	ENOG4105WWX	n-acetylmuramoyl-l-alanine amidase
HKM25_RS09775	ENOG4108KGH	TRANSCRIPTIONal
HKM25_RS09785	ENOG4105K8N	protein family UPF0079, ATPase
HKM25_RS09805	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HKM25_RS09840	ENOG4105ZT7	DNA-entry nuclease
HKM25_RS09850	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HKM25_RS09860	ENOG41063PX	domain protein
HKM25_RS09870	ENOG4106H78	methyltransferase
HKM25_RS09880	ENOG4105HFZ	Membrane
HKM25_RS09885	ENOG4108RWN	rrna methyltransferase
HKM25_RS09895	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
HKM25_RS09900	ENOG4105F1A	Pyruvate formate-lyase
HKM25_RS09910	ENOG4105DFT	pur operon repressor
HKM25_RS09925	ENOG4105FJ0	thiamine
HKM25_RS09930	ENOG4105DJV	ribulose-phosphate 3-epimerase
HKM25_RS09935	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HKM25_RS09940	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HKM25_RS09950	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HKM25_RS09970	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
HKM25_RS09975	ENOG4105F8V	Hydrolase, tatD family
HKM25_RS09995	ENOG4105CHM	Aminotransferase
HKM25_RS10005	ENOG4107YZX	Universal stress protein
HKM25_RS10010	ENOG4108X4Q	Hydrolase
HKM25_RS10015	ENOG4107RB3	L-asparaginase
HKM25_RS10025	ENOG4105ETE	Transcriptional regulator (LacI family
HKM25_RS10035	ENOG4105BZU	Histidine kinase
HKM25_RS10040	ENOG4105KCT	ABC transporter
HKM25_RS10045	ENOG4108M15	ABC transporter
HKM25_RS10150	ENOG4105BZ4	penicillin-binding protein
HKM25_RS10155	ENOG4105C34	Pseudouridine synthase
HKM25_RS10160	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HKM25_RS10175	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HKM25_RS10185	ENOG4108JJB	ABC transporter
HKM25_RS10190	ENOG4108TZY	GntR Family Transcriptional Regulator
HKM25_RS10195	ENOG4105CS2	ec 3.2.1.21
HKM25_RS10200	ENOG4105CK1	PTS System
HKM25_RS10210	ENOG4105VCP	PTS System
HKM25_RS10215	ENOG4105C0A	alcohol dehydrogenase
HKM25_RS10225	ENOG4107ZCW	Low molecular weight phosphotyrosine protein phosphatase
HKM25_RS10235	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HKM25_RS10255	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
HKM25_RS10265	ENOG4106ETB	IIa component
HKM25_RS10275	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HKM25_RS10290	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKM25_RS10335	ENOG4106855	Competence protein
HKM25_RS10355	ENOG4105E2A	Dehydrogenase
HKM25_RS10360	ENOG4105CE4	GlcNAc 6-P deacetylase
HKM25_RS10385	ENOG4105KA3	membrAne
HKM25_RS10400	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HKM25_RS10405	ENOG4105UQX	Mate efflux family protein
HKM25_RS10410	ENOG4105D98	threonine synthase
HKM25_RS10435	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
HKM25_RS10450	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HKM25_RS10560	ENOG4105BZ1	(ABC) transporter
HKM25_RS10570	ENOG4105BZ1	(ABC) transporter
HKM25_RS10580	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HKM25_RS10600	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HKM25_RS10605	ENOG4105BZU	Histidine kinase
HKM25_RS10610	ENOG4107S17	Phosphate-binding protein
HKM25_RS10615	ENOG4105C8U	phosphate abc transporter
HKM25_RS10625	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HKM25_RS10630	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HKM25_RS10650	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HKM25_RS10660	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HKM25_RS10675	ENOG4108UZ3	Transporter
HKM25_RS10680	ENOG4105BZ4	penicillin-binding protein
HKM25_RS10700	ENOG4105DHI	Methyltransferase
HKM25_RS10710	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HKM25_RS10715	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
HKM25_RS10720	ENOG4107FKK	extracellular solute-binding protein family 1
HKM25_RS10725	ENOG4105D56	permease protein
HKM25_RS10730	ENOG4105EG2	ABC transporter, permease
HKM25_RS10735	ENOG4108VP7	maltodextrose utilization protein MalA
HKM25_RS10740	ENOG4105FKQ	transcriptional regulator
HKM25_RS10750	ENOG4107AYK	membrAne
HKM25_RS10755	ENOG4105C9M	aspartyl-trna synthetase
HKM25_RS10785	ENOG4105VZ8	Transcriptional regulator
HKM25_RS10815	ENOG4105VG1	fes assembly suf system protein
HKM25_RS10830	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HKM25_RS10835	ENOG4108HHA	Transketolase
HKM25_RS10850	ENOG4106ETB	IIa component
HKM25_RS10905	ENOG4105C8I	hydrolase, family 38
HKM25_RS10915	ENOG4105CWX	Alpha-1,2-mannosidase
HKM25_RS10935	ENOG4105C5B	carbamate kinase
HKM25_RS10940	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HKM25_RS10945	ENOG4107QSE	Dipeptidase
HKM25_RS10955	ENOG41069UX	Beta-N-acetyl-hexosaminidase
HKM25_RS10970	ENOG4105C0A	alcohol dehydrogenase
HKM25_RS10990	ENOG4105F3R	pts system mannose fructose sorbose family iid
HKM25_RS11000	ENOG4108IQ3	PTS system
HKM25_RS11020	ENOG4105DET	Rhamnulokinase
HKM25_RS11030	ENOG4105DSE	periplasmic solute binding protein
HKM25_RS11040	ENOG4105FDK	ABC transporter
HKM25_RS11045	ENOG41067TZ	transcriptional regulator, MarR family
HKM25_RS11050	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
HKM25_RS11060	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HKM25_RS11085	ENOG4105EKQ	RNA-directed DNA polymerase
HKM25_RS11100	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HKM25_RS11105	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HKM25_RS11125	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HKM25_RS11135	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
HKM25_RS11140	ENOG4105BZU	Histidine kinase
HKM25_RS11145	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKM25_RS11150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HKM25_RS11170	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HKM25_RS11190	ENOG4105CDU	Replicative dna helicase
HKM25_RS11210	ENOG41081UC	Inherit from COG: Competence protein
HKM25_RS11220	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HKM25_RS11240	ENOG41068JE	domain protein
HKM25_RS11250	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HKM25_RS11255	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HKM25_RS11260	ENOG4108JJB	ABC transporter
HKM25_RS11265	ENOG4108JJB	ABC transporter
HKM25_RS11270	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HKM25_RS11285	ENOG4105C1V	Peptidase, M16
HKM25_RS11290	ENOG410848D	S4 domain protein YaaA
HKM25_RS11300	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HKM25_RS11305	ENOG4105C31	Tryptophanyl-tRNA synthetase
HKM25_RS11310	ENOG4105C5H	ABC transporter
HKM25_RS11320	ENOG4105ECB	domain protein
HKM25_RS11330	ENOG4105ECB	domain protein
HKM25_RS11375	ENOG4105C0H	protease
HKM25_RS11380	ENOG4105FA0	parb-like partition protein