locus-tag	class	description
EL334_RS00010	COG0592	DNA-directed DNA polymerase activity
EL334_RS00020	COG0012	GTP binding
EL334_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EL334_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EL334_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EL334_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EL334_RS00130	COG0756	dUTP diphosphatase activity
EL334_RS00140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EL334_RS00160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EL334_RS00185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL334_RS00185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL334_RS00190	COG1832	CoA-binding protein
EL334_RS00195	COG2855	membrane
EL334_RS00200	COG0436	Aminotransferase
EL334_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EL334_RS00230	COG2274	protein secretion by the type I secretion system
EL334_RS00235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL334_RS00250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EL334_RS00265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EL334_RS00280	COG0151	Belongs to the GarS family
EL334_RS00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EL334_RS00310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EL334_RS00315	COG3583	domain protein
EL334_RS00315	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EL334_RS00315	COG3064	Membrane
EL334_RS00330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL334_RS00335	COG3715	PTS system
EL334_RS00340	COG3716	PTS system mannose fructose sorbose family IID component
EL334_RS00350	COG2222	sugar isomerase
EL334_RS00360	COG2514	catechol 2,3-dioxygenase activity
EL334_RS00395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EL334_RS00400	COG0569	domain protein
EL334_RS00430	COG5002	protein histidine kinase activity
EL334_RS00440	COG0582	viral genome integration into host DNA
EL334_RS00505	COG4209	transmembrane transport
EL334_RS00510	COG0395	ABC-type sugar transport system, permease component
EL334_RS00520	COG1653	transport
EL334_RS00560	COG1695	Transcriptional regulator
EL334_RS00590	COG0546	phosphoglycolate phosphatase activity
EL334_RS00595	COG1760	l-serine dehydratase
EL334_RS00600	COG1760	l-serine dehydratase
EL334_RS00615	COG2274	protein secretion by the type I secretion system
EL334_RS00710	COG0494	nUDIX hydrolase
EL334_RS00715	COG0445	tRNA wobble uridine modification
EL334_RS00750	COG1214	PFAM Peptidase M22, glycoprotease
EL334_RS00785	COG0438	transferase activity, transferring glycosyl groups
EL334_RS00820	COG1396	sequence-specific DNA binding
EL334_RS00865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL334_RS00870	COG1464	Belongs to the NlpA lipoprotein family
EL334_RS00875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EL334_RS00880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EL334_RS00900	COG2972	Histidine kinase
EL334_RS00905	COG4753	response regulator
EL334_RS00905	COG2207	Transcriptional regulator
EL334_RS00915	COG1780	Probably involved in ribonucleotide reductase function
EL334_RS00955	COG0019	diaminopimelate decarboxylase activity
EL334_RS00995	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EL334_RS00995	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EL334_RS01015	COG2818	Glycosylase
EL334_RS01040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EL334_RS01045	COG0006	proline dipeptidase activity
EL334_RS01055	COG1393	Belongs to the ArsC family
EL334_RS01080	COG0285	dihydrofolate synthase activity
EL334_RS01090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EL334_RS01120	COG0602	queuosine metabolic process
EL334_RS01155	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EL334_RS01180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EL334_RS01220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EL334_RS01235	COG0201	protein transport
EL334_RS01245	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EL334_RS01250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EL334_RS01260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EL334_RS01265	COG0202	RNA polymerase activity
EL334_RS01275	COG3830	Belongs to the UPF0237 family
EL334_RS01320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EL334_RS01325	COG1349	DNA-binding transcription factor activity
EL334_RS01335	COG1447	Phosphotransferase system cellobiose-specific component IIA
EL334_RS01340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS01345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS01350	COG1882	Formate acetyltransferase
EL334_RS01365	COG0495	leucyl-tRNA aminoacylation
EL334_RS01405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EL334_RS01410	COG4589	Belongs to the CDS family
EL334_RS01415	COG0750	zinc metalloprotease
EL334_RS01425	COG2723	6-phospho-beta-galactosidase activity
EL334_RS01430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EL334_RS01440	COG1523	belongs to the glycosyl hydrolase 13 family
EL334_RS01465	COG2176	DNA-directed DNA polymerase activity
EL334_RS01485	COG2309	aminopeptidase activity
EL334_RS01490	COG2261	transglycosylase associated protein
EL334_RS01495	COG1187	pseudouridine synthase activity
EL334_RS01505	COG3579	cysteine-type endopeptidase activity
EL334_RS01510	COG3716	PTS system mannose fructose sorbose family IID component
EL334_RS01515	COG3715	PTS system
EL334_RS01525	COG1064	alcohol dehydrogenase
EL334_RS01530	COG0561	phosphatase activity
EL334_RS01535	COG2252	PERMEase
EL334_RS01545	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EL334_RS01550	COG0285	dihydrofolate synthase activity
EL334_RS01560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EL334_RS01560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EL334_RS01570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EL334_RS01630	COG1373	ATPase (AAA superfamily
EL334_RS01650	COG2723	6-phospho-beta-galactosidase activity
EL334_RS01665	COG3711	transcriptional antiterminator
EL334_RS01665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL334_RS01695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS01715	COG0386	Belongs to the glutathione peroxidase family
EL334_RS01720	COG5492	domain, Protein
EL334_RS01750	COG1028	Short-chain dehydrogenase reductase Sdr
EL334_RS01760	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EL334_RS01765	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL334_RS01770	COG3715	PTS system
EL334_RS01775	COG3716	PTS system mannose fructose sorbose family IID component
EL334_RS01790	COG1609	Transcriptional regulator
EL334_RS01820	COG4839	cell division protein FtsL
EL334_RS01825	COG0768	penicillin binding
EL334_RS01850	COG0366	Alpha amylase catalytic
EL334_RS01870	COG4464	protein tyrosine phosphatase activity
EL334_RS01875	COG3944	biosynthesis protein
EL334_RS01880	COG0489	protein tyrosine kinase activity
EL334_RS01925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EL334_RS01930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EL334_RS01945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EL334_RS01990	COG4166	transmembrane transport
EL334_RS02000	COG0366	Alpha amylase catalytic
EL334_RS02005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL334_RS02030	COG0116	Belongs to the methyltransferase superfamily
EL334_RS02040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EL334_RS02045	COG0745	RESPONSE REGULATOR receiver
EL334_RS02080	COG4585	Histidine kinase
EL334_RS02085	COG2197	response regulator
EL334_RS02125	COG2213	PTS system mannitol-specific
EL334_RS02130	COG3711	transcriptional antiterminator
EL334_RS02135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL334_RS02150	COG0544	peptidyl-prolyl cis-trans isomerase activity
EL334_RS02155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EL334_RS02160	COG0681	Belongs to the peptidase S26 family
EL334_RS02165	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EL334_RS02185	COG1115	amino acid carrier protein
EL334_RS02210	COG0527	aspartate kinase activity
EL334_RS02220	COG1024	Enoyl-CoA hydratase
EL334_RS02225	COG1846	Transcriptional regulator
EL334_RS02235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EL334_RS02245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EL334_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
EL334_RS02255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EL334_RS02270	COG0439	Biotin carboxylase
EL334_RS02275	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EL334_RS02325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EL334_RS02340	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EL334_RS02355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EL334_RS02365	COG1461	Dihydroxyacetone kinase
EL334_RS02375	COG0028	Belongs to the TPP enzyme family
EL334_RS02380	COG0440	acetolactate synthase activity
EL334_RS02400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EL334_RS02420	COG0765	amino acid transport
EL334_RS02440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EL334_RS02450	COG1882	Formate acetyltransferase
EL334_RS02470	COG1846	Transcriptional regulator
EL334_RS02470	COG1940	carbohydrate kinase activity
EL334_RS02475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS02485	COG1447	Phosphotransferase system cellobiose-specific component IIA
EL334_RS02490	COG2723	6-phospho-beta-galactosidase activity
EL334_RS02495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS02495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS02500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EL334_RS02505	COG0569	domain protein
EL334_RS02520	COG1122	ATPase activity
EL334_RS02535	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EL334_RS02540	COG0671	phosphoesterase, PA-phosphatase related
EL334_RS02560	COG0504	CTP synthase activity
EL334_RS02565	COG1283	sodium-dependent phosphate transmembrane transporter activity
EL334_RS02585	COG0789	Transcriptional regulator
EL334_RS02590	COG0174	glutamine synthetase
EL334_RS02615	COG4974	Belongs to the 'phage' integrase family
EL334_RS02670	COG0484	heat shock protein binding
EL334_RS02685	COG0537	adenosine 5'-monophosphoramidase activity
EL334_RS02690	COG1131	(ABC) transporter
EL334_RS02720	COG3290	protein histidine kinase activity
EL334_RS02730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL334_RS02805	COG1266	CAAX protease self-immunity
EL334_RS02825	COG0195	Participates in both transcription termination and antitermination
EL334_RS02830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EL334_RS02845	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EL334_RS02885	COG0519	Catalyzes the synthesis of GMP from XMP
EL334_RS02895	COG0525	valine-tRNA ligase activity
EL334_RS02930	COG3711	transcriptional antiterminator
EL334_RS02935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL334_RS02935	COG2190	(PTS) system
EL334_RS02935	COG1263	PTS System
EL334_RS02950	COG0456	acetyltransferase
EL334_RS02955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL334_RS02955	COG0072	phenylalanine-tRNA ligase activity
EL334_RS02970	COG3620	sequence-specific DNA binding
EL334_RS02995	COG1045	serine acetyltransferase
EL334_RS03010	COG0215	cysteine-tRNA ligase activity
EL334_RS03015	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EL334_RS03030	COG0577	efflux transmembrane transporter activity
EL334_RS03035	COG1136	(ABC) transporter
EL334_RS03040	COG0577	efflux transmembrane transporter activity
EL334_RS03045	COG0745	RESPONSE REGULATOR receiver
EL334_RS03050	COG5002	protein histidine kinase activity
EL334_RS03055	COG0191	fructose-bisphosphate aldolase activity
EL334_RS03060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EL334_RS03065	COG0765	amino acid transport
EL334_RS03070	COG0765	amino acid transport
EL334_RS03075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL334_RS03085	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EL334_RS03085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EL334_RS03125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL334_RS03140	COG1573	uracil-dna glycosylase
EL334_RS03155	COG1114	Component of the transport system for branched-chain amino acids
EL334_RS03160	COG1363	Peptidase, m42
EL334_RS03205	COG4555	ABC transporter
EL334_RS03235	COG1404	Belongs to the peptidase S8 family
EL334_RS03250	COG3775	system Galactitol-specific IIC component
EL334_RS03255	COG3250	beta-galactosidase activity
EL334_RS03275	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EL334_RS03295	COG0785	Cytochrome C biogenesis protein
EL334_RS03300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL334_RS03305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL334_RS03305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL334_RS03315	COG2207	Transcriptional regulator
EL334_RS03315	COG4753	response regulator
EL334_RS03320	COG2972	Histidine kinase
EL334_RS03325	COG4475	Protein of unknown function (DUF436)
EL334_RS03330	COG3064	Membrane
EL334_RS03335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EL334_RS03350	COG1940	carbohydrate kinase activity
EL334_RS03365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EL334_RS03370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EL334_RS03375	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EL334_RS03385	COG0300	oxidoreductase activity
EL334_RS03400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL334_RS03410	COG1187	pseudouridine synthase activity
EL334_RS03415	COG1217	gtp-binding protein TYPA
EL334_RS03435	COG1136	(ABC) transporter
EL334_RS03450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EL334_RS03455	COG0284	orotidine-5'-phosphate decarboxylase activity
EL334_RS03460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EL334_RS03485	COG1131	(ABC) transporter
EL334_RS03490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL334_RS03495	COG1126	abc transporter atp-binding protein
EL334_RS03510	COG1304	FMN binding
EL334_RS03520	COG1304	FMN binding
EL334_RS03535	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EL334_RS03540	COG0352	thiamine-phosphate diphosphorylase activity
EL334_RS03555	COG4172	Belongs to the ABC transporter superfamily
EL334_RS03565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EL334_RS03580	COG0352	thiamine-phosphate diphosphorylase activity
EL334_RS03600	COG2217	Heavy metal translocating P-type atpase
EL334_RS03605	COG0028	Belongs to the TPP enzyme family
EL334_RS03625	COG2723	6-phospho-beta-galactosidase activity
EL334_RS03630	COG1482	cell wall glycoprotein biosynthetic process
EL334_RS03635	COG0733	neurotransmitter:sodium symporter activity
EL334_RS03640	COG0789	Transcriptional regulator
EL334_RS03650	COG2081	HI0933 family
EL334_RS03655	COG1307	EDD domain protein, DegV family
EL334_RS03665	COG2131	deaminase
EL334_RS03670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EL334_RS03715	COG0517	IMP dehydrogenase activity
EL334_RS03715	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EL334_RS03715	COG0617	tRNA 3'-terminal CCA addition
EL334_RS03725	COG2884	Cell division ATP-binding protein ftsE
EL334_RS03730	COG2177	Part of the ABC transporter FtsEX involved in
EL334_RS03735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL334_RS03735	COG1263	PTS System
EL334_RS03735	COG2190	(PTS) system
EL334_RS03745	COG0513	Belongs to the DEAD box helicase family
EL334_RS03760	COG0167	dihydroorotate dehydrogenase activity
EL334_RS03770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EL334_RS03775	COG4470	Protein conserved in bacteria
EL334_RS03790	COG0488	(ABC) transporter
EL334_RS03820	COG1837	Belongs to the UPF0109 family
EL334_RS03845	COG1328	CTP reductase activity
EL334_RS03845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EL334_RS03855	COG4443	Transcriptional Coactivator p15 (PC4)
EL334_RS03865	COG1268	BioY protein
EL334_RS03870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EL334_RS03875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL334_RS03880	COG1136	(ABC) transporter
EL334_RS03885	COG0577	efflux transmembrane transporter activity
EL334_RS03890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL334_RS03890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL334_RS03905	COG4989	oxidoreductase activity
EL334_RS03915	COG1028	Short-chain dehydrogenase reductase Sdr
EL334_RS03945	COG0745	RESPONSE REGULATOR receiver
EL334_RS03950	COG5002	protein histidine kinase activity
EL334_RS03975	COG0772	Belongs to the SEDS family
EL334_RS03980	COG0693	protein deglycase activity
EL334_RS03990	COG0187	DNA topoisomerase II activity
EL334_RS04045	COG0542	response to heat
EL334_RS04050	COG4703	Protein of unknown function (DUF1797)
EL334_RS04055	COG0765	amino acid transport
EL334_RS04060	COG1126	abc transporter atp-binding protein
EL334_RS04065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EL334_RS04070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EL334_RS04090	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EL334_RS04145	COG2813	Specifically methylates the guanine in position
EL334_RS04150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EL334_RS04160	COG0295	cytidine deaminase activity
EL334_RS04165	COG1744	ABC transporter substrate-binding protein PnrA-like
EL334_RS04170	COG3845	ABC transporter
EL334_RS04175	COG4603	Belongs to the binding-protein-dependent transport system permease family
EL334_RS04180	COG1079	Belongs to the binding-protein-dependent transport system permease family
EL334_RS04195	COG0187	DNA topoisomerase II activity
EL334_RS04200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EL334_RS04205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EL334_RS04210	COG4166	transmembrane transport
EL334_RS04245	COG0539	negative regulation of cytoplasmic translation
EL334_RS04255	COG1956	GAF domain-containing protein
EL334_RS04260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EL334_RS04275	COG0719	Fe-S assembly protein
EL334_RS04280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EL334_RS04290	COG0719	Fe-S assembly protein
EL334_RS04295	COG1686	Belongs to the peptidase S11 family
EL334_RS04300	COG0628	permease
EL334_RS04315	COG1349	DNA-binding transcription factor activity
EL334_RS04320	COG1105	Belongs to the carbohydrate kinase PfkB family
EL334_RS04325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL334_RS04325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL334_RS04325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL334_RS04330	COG1674	ftsk spoiiie
EL334_RS04330	COG0697	spore germination
EL334_RS04345	COG1104	cysteine desulfurase activity
EL334_RS04415	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EL334_RS04430	COG1438	arginine binding
EL334_RS04450	COG0469	pyruvate kinase activity
EL334_RS04500	COG3689	TIGRFAM TIGR03943 family protein
EL334_RS04505	COG0701	Predicted permease
EL334_RS04520	COG3955	Domain of unknown function (DUF1919)
EL334_RS04525	COG2183	response to ionizing radiation
EL334_RS04545	COG1136	(ABC) transporter
EL334_RS04550	COG0577	efflux transmembrane transporter activity
EL334_RS04570	COG1982	Orn Lys Arg decarboxylase major
EL334_RS04580	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EL334_RS04600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EL334_RS04605	COG0561	phosphatase activity
EL334_RS04625	COG0583	DNA-binding transcription factor activity
EL334_RS04630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EL334_RS04635	COG0564	pseudouridine synthase activity
EL334_RS04640	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EL334_RS04655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EL334_RS04665	COG0470	DNA polymerase III
EL334_RS04705	COG0528	UMP kinase activity
EL334_RS04715	COG2996	Protein conserved in bacteria
EL334_RS04725	COG1702	phosphate starvation-inducible protein PhoH
EL334_RS04745	COG0686	Belongs to the AlaDH PNT family
EL334_RS04750	COG0686	Belongs to the AlaDH PNT family
EL334_RS04755	COG0686	Belongs to the AlaDH PNT family
EL334_RS04760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EL334_RS04765	COG1555	photosystem II stabilization
EL334_RS04765	COG1596	polysaccharide export
EL334_RS04770	COG2333	competence protein COMEC
EL334_RS04770	COG0658	competence protein
EL334_RS04780	COG1131	(ABC) transporter
EL334_RS04810	COG0543	2 iron, 2 sulfur cluster binding
EL334_RS04815	COG0167	dihydroorotate dehydrogenase activity
EL334_RS04820	COG5263	repeat protein
EL334_RS04820	COG4193	domain, Protein
EL334_RS04825	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EL334_RS04835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EL334_RS04845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EL334_RS04850	COG0237	dephospho-CoA kinase activity
EL334_RS04855	COG2814	Major facilitator Superfamily
EL334_RS04860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EL334_RS04870	COG0557	exoribonuclease II activity
EL334_RS04880	COG0500	methyltransferase
EL334_RS04880	COG3615	Tellurite resistance protein tehB
EL334_RS04895	COG4122	O-methyltransferase activity
EL334_RS04925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EL334_RS04940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EL334_RS04945	COG0494	nUDIX hydrolase
EL334_RS04955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EL334_RS04965	COG2176	DNA-directed DNA polymerase activity
EL334_RS04970	COG0584	glycerophosphoryl diester phosphodiesterase
EL334_RS04990	COG0785	Cytochrome C biogenesis protein
EL334_RS04995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL334_RS05000	COG0531	amino acid
EL334_RS05005	COG0803	Belongs to the bacterial solute-binding protein 9 family
EL334_RS05005	COG3443	Belongs to the bacterial solute-binding protein 9 family
EL334_RS05045	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EL334_RS05050	COG1970	mechanosensitive ion channel activity
EL334_RS05060	COG4708	membrane
EL334_RS05075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EL334_RS05085	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EL334_RS05090	COG1942	4-Oxalocrotonate Tautomerase
EL334_RS05095	COG1435	thymidine kinase activity
EL334_RS05105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EL334_RS05110	COG2890	protein-(glutamine-N5) methyltransferase activity
EL334_RS05135	COG0741	lytic transglycosylase activity
EL334_RS05145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EL334_RS05170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL334_RS05175	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL334_RS05230	COG1597	lipid kinase activity
EL334_RS05265	COG0772	Belongs to the SEDS family
EL334_RS05270	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EL334_RS05285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EL334_RS05290	COG0358	DNA primase activity
EL334_RS05295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EL334_RS05300	COG2151	metal-sulfur cluster biosynthetic enzyme
EL334_RS05305	COG0438	transferase activity, transferring glycosyl groups
EL334_RS05310	COG0438	transferase activity, transferring glycosyl groups
EL334_RS05335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EL334_RS05345	COG4109	DRTGG domain
EL334_RS05350	COG0024	Methionine aminopeptidase
EL334_RS05365	COG0210	DNA helicase
EL334_RS05375	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EL334_RS05395	COG1104	cysteine desulfurase activity
EL334_RS05400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EL334_RS05410	COG2357	RelA SpoT domain protein
EL334_RS05420	COG0564	pseudouridine synthase activity
EL334_RS05425	COG0280	phosphate acetyltransferase
EL334_RS05465	COG0196	riboflavin kinase activity
EL334_RS05470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EL334_RS05475	COG1307	EDD domain protein, DegV family
EL334_RS05485	COG0488	(ABC) transporter
EL334_RS05505	COG1523	belongs to the glycosyl hydrolase 13 family
EL334_RS05510	COG1012	belongs to the aldehyde dehydrogenase family
EL334_RS05520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EL334_RS05530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EL334_RS05570	COG0582	viral genome integration into host DNA
EL334_RS05610	COG3583	domain protein
EL334_RS05610	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EL334_RS05630	COG0270	DNA (cytosine-5-)-methyltransferase activity
EL334_RS05735	COG2946	Replication initiation factor
EL334_RS05785	COG0741	lytic transglycosylase activity
EL334_RS05785	COG0791	NLP P60 protein
EL334_RS05845	COG1136	(ABC) transporter
EL334_RS05905	COG1396	sequence-specific DNA binding
EL334_RS05910	COG0542	response to heat
EL334_RS05955	COG1396	sequence-specific DNA binding
EL334_RS05960	COG0542	response to heat
EL334_RS05970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EL334_RS05995	COG3843	relaxase mobilization nuclease domain protein
EL334_RS06000	COG1396	sequence-specific DNA binding
EL334_RS06010	COG0582	viral genome integration into host DNA
EL334_RS06015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EL334_RS06035	COG0095	Lipoate-protein ligase
EL334_RS06040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EL334_RS06045	COG0508	dehydrogenase complex catalyzes the overall conversion of
EL334_RS06050	COG0022	dehydrogenase e1 component
EL334_RS06055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EL334_RS06060	COG0534	Mate efflux family protein
EL334_RS06070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EL334_RS06075	COG1051	belongs to the nudix hydrolase family
EL334_RS06090	COG1011	Hydrolase
EL334_RS06095	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EL334_RS06110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL334_RS06115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EL334_RS06120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EL334_RS06125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EL334_RS06155	COG2723	6-phospho-beta-galactosidase activity
EL334_RS06170	COG3711	transcriptional antiterminator
EL334_RS06175	COG3684	Belongs to the aldolase LacD family
EL334_RS06225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EL334_RS06230	COG0497	DNA recombination
EL334_RS06235	COG1438	arginine binding
EL334_RS06240	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EL334_RS06255	COG1570	exodeoxyribonuclease VII activity
EL334_RS06275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EL334_RS06285	COG2873	o-acetylhomoserine
EL334_RS06290	COG2873	o-acetylhomoserine
EL334_RS06305	COG3764	Sortase (surface protein transpeptidase)
EL334_RS06310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EL334_RS06340	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EL334_RS06345	COG5002	protein histidine kinase activity
EL334_RS06350	COG0745	RESPONSE REGULATOR receiver
EL334_RS06355	COG1194	a g-specific adenine glycosylase
EL334_RS06375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EL334_RS06380	COG4684	Psort location CytoplasmicMembrane, score
EL334_RS06390	COG1827	regulation of RNA biosynthetic process
EL334_RS06395	COG2816	NAD+ diphosphatase activity
EL334_RS06420	COG0765	amino acid transport
EL334_RS06425	COG1126	abc transporter atp-binding protein
EL334_RS06430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EL334_RS06435	COG0552	protein localization to endoplasmic reticulum
EL334_RS06440	COG0561	phosphatase activity
EL334_RS06445	COG0561	phosphatase activity
EL334_RS06450	COG1196	nuclear chromosome segregation
EL334_RS06475	COG1401	restriction endodeoxyribonuclease activity
EL334_RS06485	COG0066	3-isopropylmalate dehydratase activity
EL334_RS06510	COG3142	Participates in the control of copper homeostasis
EL334_RS06515	COG2832	Protein of unknown function (DUF454)
EL334_RS06520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EL334_RS06530	COG0758	DNA mediated transformation
EL334_RS06535	COG4750	Nucleotidyl transferase
EL334_RS06550	COG1063	alcohol dehydrogenase
EL334_RS06565	COG3475	LICD family
EL334_RS06570	COG3475	LICD family
EL334_RS06580	COG0505	Belongs to the CarA family
EL334_RS06595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EL334_RS06610	COG0488	(ABC) transporter
EL334_RS06620	COG1704	LemA family
EL334_RS06635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EL334_RS06650	COG1078	dGTPase activity
EL334_RS06670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EL334_RS06675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EL334_RS06680	COG0077	Prephenate dehydratase
EL334_RS06680	COG1605	Chorismate mutase
EL334_RS06685	COG0716	FMN binding
EL334_RS06690	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EL334_RS06710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EL334_RS06795	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EL334_RS06800	COG1269	ATP hydrolysis coupled proton transport
EL334_RS06815	COG0673	inositol 2-dehydrogenase activity
EL334_RS06820	COG4409	exo-alpha-(2->6)-sialidase activity
EL334_RS06830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EL334_RS06835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EL334_RS06840	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EL334_RS06845	COG1737	Transcriptional regulator
EL334_RS06870	COG1136	(ABC) transporter
EL334_RS06870	COG0577	efflux transmembrane transporter activity
EL334_RS06880	COG0515	serine threonine protein kinase
EL334_RS06930	COG0402	S-adenosylhomocysteine deaminase activity
EL334_RS06940	COG1132	(ABC) transporter
EL334_RS06945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL334_RS06945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL334_RS06980	COG1215	transferase activity, transferring glycosyl groups
EL334_RS06990	COG3475	LICD family
EL334_RS07000	COG0077	Prephenate dehydratase
EL334_RS07005	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EL334_RS07020	COG0287	Prephenate dehydrogenase
EL334_RS07045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EL334_RS07060	COG1131	(ABC) transporter
EL334_RS07100	COG3842	ATPase activity
EL334_RS07115	COG3527	Alpha-acetolactate decarboxylase
EL334_RS07120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EL334_RS07125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL334_RS07130	COG0704	Plays a role in the regulation of phosphate uptake
EL334_RS07135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EL334_RS07140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EL334_RS07145	COG0581	inorganic phosphate transmembrane transporter activity
EL334_RS07150	COG0573	inorganic phosphate transmembrane transporter activity
EL334_RS07155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EL334_RS07160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EL334_RS07160	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EL334_RS07165	COG0483	inositol monophosphate 1-phosphatase activity
EL334_RS07175	COG1393	Belongs to the ArsC family
EL334_RS07185	COG0647	UMP catabolic process
EL334_RS07195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EL334_RS07215	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EL334_RS07230	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EL334_RS07245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EL334_RS07255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EL334_RS07275	COG1131	(ABC) transporter
EL334_RS07300	COG0826	peptidase U32
EL334_RS07330	COG1132	(ABC) transporter
EL334_RS07335	COG1132	(ABC) transporter
EL334_RS07365	COG1129	ABC transporter
EL334_RS07390	COG2188	Transcriptional regulator
EL334_RS07395	COG0697	spore germination
EL334_RS07400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EL334_RS07415	COG0561	phosphatase activity
EL334_RS07450	COG0492	ferredoxin-NADP+ reductase activity
EL334_RS07460	COG1126	abc transporter atp-binding protein
EL334_RS07470	COG1393	Belongs to the ArsC family
EL334_RS07475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EL334_RS07490	COG1272	protein, Hemolysin III
EL334_RS07520	COG3976	FMN-binding domain protein
EL334_RS07520	COG0431	NADPH-dependent FMN reductase
EL334_RS07520	COG1053	succinate dehydrogenase
EL334_RS07550	COG0656	L-ascorbic acid biosynthetic process
EL334_RS07555	COG0726	polysaccharide deacetylase
EL334_RS07600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EL334_RS07640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EL334_RS07655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL334_RS07660	COG1126	abc transporter atp-binding protein
EL334_RS07675	COG0628	permease
EL334_RS07680	COG2706	6-phosphogluconolactonase activity
EL334_RS07740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EL334_RS07765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EL334_RS07770	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EL334_RS07775	COG0626	cystathionine gamma-synthase activity
EL334_RS07780	COG1132	(ABC) transporter
EL334_RS07790	COG4166	transmembrane transport
EL334_RS07795	COG2244	polysaccharide biosynthetic process
EL334_RS07800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EL334_RS07825	COG2827	Endonuclease containing a URI domain
EL334_RS07830	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EL334_RS07835	COG1098	S1 RNA binding domain
EL334_RS07845	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EL334_RS07850	COG0629	single-stranded DNA binding
EL334_RS07860	COG0017	Asparaginyl-tRNA synthetase
EL334_RS07870	COG0436	Aminotransferase
EL334_RS07895	COG3711	transcriptional antiterminator
EL334_RS07920	COG0242	peptide deformylase activity
EL334_RS07925	COG0625	glutathione transferase activity
EL334_RS07935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EL334_RS07940	COG0488	(ABC) transporter
EL334_RS07945	COG0617	tRNA 3'-terminal CCA addition
EL334_RS07955	COG1307	EDD domain protein, DegV family
EL334_RS07975	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EL334_RS07995	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EL334_RS08005	COG0251	oxidation-reduction process
EL334_RS08025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EL334_RS08040	COG5263	repeat protein
EL334_RS08040	COG4193	domain, Protein
EL334_RS08050	COG3935	DnaD domain protein
EL334_RS08065	COG2226	methyltransferase
EL334_RS08070	COG3842	ATPase activity
EL334_RS08080	COG1335	isochorismatase
EL334_RS08085	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EL334_RS08095	COG0513	Belongs to the DEAD box helicase family
EL334_RS08100	COG2223	nitrite transmembrane transporter activity
EL334_RS08105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EL334_RS08110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EL334_RS08115	COG3442	glutamine amidotransferase
EL334_RS08120	COG0006	proline dipeptidase activity
EL334_RS08135	COG4720	Psort location CytoplasmicMembrane, score
EL334_RS08140	COG0351	phosphomethylpyrimidine kinase
EL334_RS08165	COG2824	Alkylphosphonate utilization operon protein PhnA
EL334_RS08185	COG0463	Glycosyl transferase, family 2
EL334_RS08190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EL334_RS08200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EL334_RS08205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EL334_RS08210	COG2384	SAM-dependent methyltransferase
EL334_RS08240	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EL334_RS08245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EL334_RS08250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL334_RS08250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL334_RS08250	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EL334_RS08255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL334_RS08275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EL334_RS08280	COG0204	Acyl-transferase
EL334_RS08295	COG2910	NAD(P)H-binding
EL334_RS08325	COG5002	protein histidine kinase activity
EL334_RS08330	COG0745	RESPONSE REGULATOR receiver
EL334_RS08345	COG1959	2 iron, 2 sulfur cluster binding
EL334_RS08410	COG3590	peptidase
EL334_RS08425	COG0803	Belongs to the bacterial solute-binding protein 9 family
EL334_RS08430	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EL334_RS08440	COG1136	(ABC) transporter
EL334_RS08440	COG0577	efflux transmembrane transporter activity
EL334_RS08465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EL334_RS08475	COG3599	regulation of cell shape
EL334_RS08495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EL334_RS08515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EL334_RS08530	COG0768	penicillin binding
EL334_RS08545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EL334_RS08565	COG2731	YhcH YjgK YiaL family protein
EL334_RS08570	COG0395	ABC-type sugar transport system, permease component
EL334_RS08575	COG1175	transmembrane transport
EL334_RS08585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL334_RS08585	COG2190	(PTS) system
EL334_RS08585	COG1263	PTS System
EL334_RS08610	COG1175	transmembrane transport
EL334_RS08615	COG1653	transport
EL334_RS08645	COG3458	cephalosporin-C deacetylase activity
EL334_RS08655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EL334_RS08670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EL334_RS08675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EL334_RS08690	COG1131	(ABC) transporter
EL334_RS08730	COG0778	Nitroreductase
EL334_RS08735	COG1484	DNA-dependent DNA replication
EL334_RS08750	COG1725	Transcriptional regulator
EL334_RS08755	COG1131	(ABC) transporter
EL334_RS08765	COG1668	transmembrane transport
EL334_RS08770	COG4152	abc transporter atp-binding protein
EL334_RS08790	COG1940	carbohydrate kinase activity
EL334_RS08795	COG1263	PTS System
EL334_RS08795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL334_RS08795	COG2190	(PTS) system
EL334_RS08805	COG1621	beta-fructofuranosidase activity
EL334_RS08810	COG1609	Transcriptional regulator
EL334_RS08820	COG3425	synthase
EL334_RS08845	COG2815	serine threonine protein kinase
EL334_RS08845	COG0515	serine threonine protein kinase
EL334_RS08850	COG0631	protein serine/threonine phosphatase activity
EL334_RS08855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EL334_RS08855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EL334_RS08865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EL334_RS08875	COG0194	GDP metabolic process
EL334_RS08885	COG4115	mRNA cleavage
EL334_RS08900	COG2226	methyltransferase
EL334_RS08905	COG0799	negative regulation of ribosome biogenesis
EL334_RS08915	COG1713	HD superfamily hydrolase involved in NAD metabolism
EL334_RS08920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EL334_RS08925	COG1534	Rna-binding protein
EL334_RS08930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EL334_RS08945	COG0668	transmembrane transport
EL334_RS08955	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EL334_RS08975	COG3118	belongs to the thioredoxin family
EL334_RS08980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EL334_RS08995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EL334_RS09010	COG1164	Oligoendopeptidase f
EL334_RS09015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EL334_RS09095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EL334_RS09105	COG1621	beta-fructofuranosidase activity
EL334_RS09110	COG1653	transport
EL334_RS09115	COG0395	ABC-type sugar transport system, permease component
EL334_RS09120	COG4209	transmembrane transport
EL334_RS09130	COG3711	transcriptional antiterminator
EL334_RS09135	COG2261	transglycosylase associated protein
EL334_RS09155	COG3237	CsbD-like
EL334_RS09175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EL334_RS09185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS09190	COG1447	Phosphotransferase system cellobiose-specific component IIA
EL334_RS09195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS09205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS09210	COG1846	Transcriptional regulator
EL334_RS09210	COG1940	carbohydrate kinase activity
EL334_RS09220	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EL334_RS09250	COG0512	Glutamine amidotransferase of anthranilate synthase
EL334_RS09255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EL334_RS09270	COG1285	pathogenesis
EL334_RS09275	COG1178	ABC-type Fe3 transport system permease component
EL334_RS09305	COG5434	Belongs to the glycosyl hydrolase 28 family
EL334_RS09315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EL334_RS09320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EL334_RS09330	COG1132	(ABC) transporter
EL334_RS09335	COG1132	(ABC) transporter
EL334_RS09355	COG0708	Exodeoxyribonuclease III
EL334_RS09375	COG2233	PERMEase
EL334_RS09400	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EL334_RS09405	COG1609	Transcriptional regulator
EL334_RS09410	COG1063	alcohol dehydrogenase
EL334_RS09415	COG0789	Transcriptional regulator
EL334_RS09420	COG1230	cation diffusion facilitator family transporter
EL334_RS09430	COG3201	nicotinamide mononucleotide transporter
EL334_RS09435	COG1174	glycine betaine transport
EL334_RS09460	COG1363	Peptidase, m42
EL334_RS09475	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL334_RS09480	COG4605	iron ion homeostasis
EL334_RS09485	COG4604	ABC transporter, ATP-binding protein
EL334_RS09490	COG4607	ABC-type enterochelin transport system periplasmic component
EL334_RS09500	COG1187	pseudouridine synthase activity
EL334_RS09520	COG0517	IMP dehydrogenase activity
EL334_RS09530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EL334_RS09545	COG0366	Alpha amylase catalytic
EL334_RS09555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL334_RS09555	COG1263	PTS System
EL334_RS09560	COG2188	Transcriptional regulator
EL334_RS09575	COG4608	Belongs to the ABC transporter superfamily
EL334_RS09580	COG0444	Belongs to the ABC transporter superfamily
EL334_RS09585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EL334_RS09590	COG0601	transmembrane transport
EL334_RS09595	COG4166	transmembrane transport
EL334_RS09605	COG0366	Alpha amylase catalytic
EL334_RS09610	COG0395	ABC-type sugar transport system, permease component
EL334_RS09615	COG1175	transmembrane transport
EL334_RS09620	COG1653	transport
EL334_RS09625	COG3345	alpha-galactosidase
EL334_RS09630	COG2207	Transcriptional regulator
EL334_RS09635	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EL334_RS09635	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EL334_RS09750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EL334_RS09805	COG4221	oxidoreductase activity
EL334_RS09810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL334_RS09815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL334_RS09945	COG5263	repeat protein
EL334_RS09945	COG5632	N-Acetylmuramoyl-L-alanine amidase
EL334_RS09970	COG1316	TRANSCRIPTIONal
EL334_RS09980	COG0802	atpase or kinase
EL334_RS10020	COG1136	(ABC) transporter
EL334_RS10020	COG0577	efflux transmembrane transporter activity
EL334_RS10050	COG1253	flavin adenine dinucleotide binding
EL334_RS10065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EL334_RS10075	COG3480	Lon protease (S16) C-terminal proteolytic domain
EL334_RS10085	COG0742	ribosomal rna small subunit methyltransferase
EL334_RS10105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EL334_RS10110	COG1254	Belongs to the acylphosphatase family
EL334_RS10120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EL334_RS10130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EL334_RS10150	COG1564	THIamine pyrophosphokinase
EL334_RS10160	COG1162	GTPase activity
EL334_RS10190	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EL334_RS10195	COG0084	hydrolase, TatD family'
EL334_RS10220	COG0436	Aminotransferase
EL334_RS10230	COG0589	response to stress
EL334_RS10235	COG0561	phosphatase activity
EL334_RS10240	COG0252	asparaginase activity
EL334_RS10245	COG1609	Transcriptional regulator
EL334_RS10250	COG2197	response regulator
EL334_RS10255	COG4585	Histidine kinase
EL334_RS10260	COG0842	Transport permease protein
EL334_RS10265	COG1131	(ABC) transporter
EL334_RS10365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EL334_RS10370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL334_RS10375	COG0564	pseudouridine synthase activity
EL334_RS10385	COG0577	efflux transmembrane transporter activity
EL334_RS10395	COG0157	Belongs to the NadC ModD family
EL334_RS10410	COG1129	ABC transporter
EL334_RS10415	COG2188	Transcriptional regulator
EL334_RS10420	COG2723	6-phospho-beta-galactosidase activity
EL334_RS10425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL334_RS10435	COG1447	Phosphotransferase system cellobiose-specific component IIA
EL334_RS10440	COG1012	belongs to the aldehyde dehydrogenase family
EL334_RS10440	COG1454	alcohol dehydrogenase
EL334_RS10450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EL334_RS10460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EL334_RS10480	COG3623	hexulose-6-phosphate isomerase
EL334_RS10490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL334_RS10500	COG3037	sugar-specific permease SgaT UlaA
EL334_RS10510	COG1847	R3H domain protein
EL334_RS10515	COG0706	membrane insertase activity
EL334_RS10560	COG4537	Required for transformation and DNA binding
EL334_RS10565	COG1459	type II secretion system
EL334_RS10570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EL334_RS10580	COG1063	alcohol dehydrogenase
EL334_RS10610	COG3759	membrane
EL334_RS10630	COG0131	Imidazoleglycerol-phosphate dehydratase
EL334_RS10630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EL334_RS10635	COG0534	Mate efflux family protein
EL334_RS10670	COG1674	ftsk spoiiie
EL334_RS10820	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EL334_RS10825	COG1132	(ABC) transporter
EL334_RS10835	COG1132	(ABC) transporter
EL334_RS10845	COG1438	arginine binding
EL334_RS10865	COG0745	RESPONSE REGULATOR receiver
EL334_RS10870	COG5002	protein histidine kinase activity
EL334_RS10875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EL334_RS10880	COG0573	inorganic phosphate transmembrane transporter activity
EL334_RS10890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EL334_RS10895	COG0704	Plays a role in the regulation of phosphate uptake
EL334_RS10915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EL334_RS10925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EL334_RS10940	COG0697	spore germination
EL334_RS10945	COG4499	WXG100 protein secretion system (Wss), protein YukC
EL334_RS10945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL334_RS10955	COG2217	Heavy metal translocating P-type atpase
EL334_RS10965	COG2226	methyltransferase
EL334_RS10985	COG0058	SHG alpha-glucan phosphorylase activity
EL334_RS10990	COG1640	4-alpha-glucanotransferase
EL334_RS10995	COG2182	Extracellular solute-binding protein
EL334_RS11000	COG1175	transmembrane transport
EL334_RS11005	COG3833	ABC-type maltose transport systems, permease component
EL334_RS11015	COG5521	maltodextrose utilization protein MalA
EL334_RS11020	COG1609	Transcriptional regulator
EL334_RS11030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EL334_RS11065	COG1476	TRANSCRIPTIONal
EL334_RS11100	COG2151	metal-sulfur cluster biosynthetic enzyme
EL334_RS11115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EL334_RS11120	COG3959	Transketolase, thiamine diphosphate binding domain
EL334_RS11135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL334_RS11155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EL334_RS11190	COG0383	alpha-mannosidase activity
EL334_RS11200	COG3537	Alpha-1,2-mannosidase
EL334_RS11225	COG0549	Belongs to the carbamate kinase family
EL334_RS11230	COG1288	antiporter activity
EL334_RS11235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EL334_RS11250	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EL334_RS11250	COG3583	domain protein
EL334_RS11250	COG3064	Membrane
EL334_RS11265	COG1454	alcohol dehydrogenase
EL334_RS11270	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
EL334_RS11275	COG0235	Class ii aldolase
EL334_RS11305	COG1175	transmembrane transport
EL334_RS11310	COG1653	transport
EL334_RS11315	COG1070	Carbohydrate kinase
EL334_RS11330	COG0803	Belongs to the bacterial solute-binding protein 9 family
EL334_RS11330	COG3443	Belongs to the bacterial solute-binding protein 9 family
EL334_RS11335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EL334_RS11340	COG1121	(ABC) transporter
EL334_RS11345	COG1846	Transcriptional regulator
EL334_RS11350	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EL334_RS11360	COG1696	Membrane protein involved in D-alanine export
EL334_RS11375	COG2211	Major facilitator Superfamily
EL334_RS11380	COG3344	reverse transcriptase
EL334_RS11405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EL334_RS11410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EL334_RS11430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EL334_RS11440	COG1755	Isoprenylcysteine carboxyl methyltransferase
EL334_RS11445	COG5002	protein histidine kinase activity
EL334_RS11450	COG0745	RESPONSE REGULATOR receiver
EL334_RS11465	COG0542	response to heat
EL334_RS11470	COG4463	regulation of RNA biosynthetic process
EL334_RS11475	COG1116	anion transmembrane transporter activity
EL334_RS11480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EL334_RS11485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EL334_RS11505	COG0305	Participates in initiation and elongation during chromosome replication
EL334_RS11525	COG1040	competence protein
EL334_RS11530	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EL334_RS11535	COG1739	Uncharacterized protein family UPF0029
EL334_RS11575	COG3942	CHAP domain
EL334_RS11585	COG1792	Involved in formation and maintenance of cell shape
EL334_RS11590	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EL334_RS11595	COG1122	ATPase activity
EL334_RS11600	COG1122	ATPase activity
EL334_RS11605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EL334_RS11615	COG0612	Peptidase, M16
EL334_RS11620	COG0612	Peptidase, M16
EL334_RS11625	COG2501	S4 domain
EL334_RS11635	COG0517	IMP dehydrogenase activity
EL334_RS11635	COG0516	GMP reductase activity
EL334_RS11640	COG0180	Tryptophanyl-tRNA synthetase
EL334_RS11645	COG0488	(ABC) transporter
EL334_RS11660	COG1511	domain protein
EL334_RS11705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EL334_RS11710	COG1475	DNA binding