locus-tag	class	description
GJE16_RS00010	COG0592	DNA-directed DNA polymerase activity
GJE16_RS00020	COG0012	GTP binding
GJE16_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GJE16_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GJE16_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GJE16_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GJE16_RS00130	COG0582	viral genome integration into host DNA
GJE16_RS00135	COG0582	viral genome integration into host DNA
GJE16_RS00190	COG0756	dUTP diphosphatase activity
GJE16_RS00200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GJE16_RS00215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GJE16_RS00235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GJE16_RS00235	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GJE16_RS00240	COG1832	CoA-binding protein
GJE16_RS00245	COG2855	membrane
GJE16_RS00250	COG0436	Aminotransferase
GJE16_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJE16_RS00300	COG1388	LysM domain
GJE16_RS00300	COG1134	teichoic acid transport
GJE16_RS00310	COG2274	protein secretion by the type I secretion system
GJE16_RS00320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJE16_RS00330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GJE16_RS00335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GJE16_RS00345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GJE16_RS00360	COG0151	Belongs to the GarS family
GJE16_RS00375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GJE16_RS00390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GJE16_RS00395	COG3064	Membrane
GJE16_RS00395	COG3583	domain protein
GJE16_RS00395	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GJE16_RS00410	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJE16_RS00415	COG3715	PTS system
GJE16_RS00420	COG3716	PTS system mannose fructose sorbose family IID component
GJE16_RS00430	COG2222	sugar isomerase
GJE16_RS00440	COG2514	catechol 2,3-dioxygenase activity
GJE16_RS00445	COG1937	Protein conserved in bacteria
GJE16_RS00475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GJE16_RS00480	COG0569	domain protein
GJE16_RS00510	COG5002	protein histidine kinase activity
GJE16_RS00540	COG4209	transmembrane transport
GJE16_RS00545	COG0395	ABC-type sugar transport system, permease component
GJE16_RS00555	COG1653	transport
GJE16_RS00575	COG0577	efflux transmembrane transporter activity
GJE16_RS00575	COG1136	(ABC) transporter
GJE16_RS00595	COG1695	Transcriptional regulator
GJE16_RS00620	COG0546	phosphoglycolate phosphatase activity
GJE16_RS00625	COG1760	l-serine dehydratase
GJE16_RS00630	COG1760	l-serine dehydratase
GJE16_RS00720	COG0494	nUDIX hydrolase
GJE16_RS00725	COG0445	tRNA wobble uridine modification
GJE16_RS00760	COG1214	PFAM Peptidase M22, glycoprotease
GJE16_RS00820	COG1396	sequence-specific DNA binding
GJE16_RS00855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJE16_RS00860	COG1464	Belongs to the NlpA lipoprotein family
GJE16_RS00865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJE16_RS00870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJE16_RS00890	COG2972	Histidine kinase
GJE16_RS00895	COG2207	Transcriptional regulator
GJE16_RS00895	COG4753	response regulator
GJE16_RS00905	COG1780	Probably involved in ribonucleotide reductase function
GJE16_RS00945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GJE16_RS00945	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GJE16_RS00965	COG2818	Glycosylase
GJE16_RS00990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GJE16_RS00995	COG0006	proline dipeptidase activity
GJE16_RS01000	COG1393	Belongs to the ArsC family
GJE16_RS01025	COG0285	dihydrofolate synthase activity
GJE16_RS01035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GJE16_RS01100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GJE16_RS01125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GJE16_RS01165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GJE16_RS01180	COG0201	protein transport
GJE16_RS01190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GJE16_RS01195	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GJE16_RS01205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GJE16_RS01210	COG0202	RNA polymerase activity
GJE16_RS01220	COG3830	Belongs to the UPF0237 family
GJE16_RS01260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GJE16_RS01265	COG1349	DNA-binding transcription factor activity
GJE16_RS01275	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJE16_RS01280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJE16_RS01285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJE16_RS01290	COG1882	Formate acetyltransferase
GJE16_RS01305	COG0495	leucyl-tRNA aminoacylation
GJE16_RS01340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GJE16_RS01345	COG4589	Belongs to the CDS family
GJE16_RS01350	COG0750	zinc metalloprotease
GJE16_RS01360	COG2723	6-phospho-beta-galactosidase activity
GJE16_RS01365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GJE16_RS01375	COG1523	belongs to the glycosyl hydrolase 13 family
GJE16_RS01400	COG2176	DNA-directed DNA polymerase activity
GJE16_RS01420	COG2309	aminopeptidase activity
GJE16_RS01425	COG2261	transglycosylase associated protein
GJE16_RS01430	COG1187	pseudouridine synthase activity
GJE16_RS01435	COG3579	cysteine-type endopeptidase activity
GJE16_RS01440	COG3716	PTS system mannose fructose sorbose family IID component
GJE16_RS01445	COG3715	PTS system
GJE16_RS01455	COG1064	alcohol dehydrogenase
GJE16_RS01460	COG0561	phosphatase activity
GJE16_RS01465	COG2252	PERMEase
GJE16_RS01475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GJE16_RS01480	COG0285	dihydrofolate synthase activity
GJE16_RS01490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GJE16_RS01490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GJE16_RS01500	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GJE16_RS01525	COG0386	Belongs to the glutathione peroxidase family
GJE16_RS01530	COG5492	domain, Protein
GJE16_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
GJE16_RS01570	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GJE16_RS01575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJE16_RS01580	COG3715	PTS system
GJE16_RS01585	COG3716	PTS system mannose fructose sorbose family IID component
GJE16_RS01600	COG1609	Transcriptional regulator
GJE16_RS01630	COG4839	cell division protein FtsL
GJE16_RS01635	COG0768	penicillin binding
GJE16_RS01660	COG0366	Alpha amylase catalytic
GJE16_RS01665	COG4166	transmembrane transport
GJE16_RS01680	COG4464	protein tyrosine phosphatase activity
GJE16_RS01685	COG3944	biosynthesis protein
GJE16_RS01690	COG0489	protein tyrosine kinase activity
GJE16_RS01705	COG3475	LICD family
GJE16_RS01725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GJE16_RS01730	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GJE16_RS01740	COG1088	dTDP-glucose 4,6-dehydratase activity
GJE16_RS01745	COG1091	dTDP-4-dehydrorhamnose reductase activity
GJE16_RS01750	COG4166	transmembrane transport
GJE16_RS01755	COG0366	Alpha amylase catalytic
GJE16_RS01760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJE16_RS01785	COG0116	Belongs to the methyltransferase superfamily
GJE16_RS01795	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GJE16_RS01800	COG0745	RESPONSE REGULATOR receiver
GJE16_RS01860	COG4585	Histidine kinase
GJE16_RS01865	COG2197	response regulator
GJE16_RS01895	COG0582	viral genome integration into host DNA
GJE16_RS01905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GJE16_RS01910	COG0681	Belongs to the peptidase S26 family
GJE16_RS01945	COG0443	Heat shock 70 kDa protein
GJE16_RS01955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GJE16_RS01970	COG4193	domain, Protein
GJE16_RS01970	COG5263	repeat protein
GJE16_RS01975	COG4193	domain, Protein
GJE16_RS01975	COG5263	repeat protein
GJE16_RS01985	COG1115	amino acid carrier protein
GJE16_RS02010	COG0527	aspartate kinase activity
GJE16_RS02015	COG1024	Enoyl-CoA hydratase
GJE16_RS02020	COG1846	Transcriptional regulator
GJE16_RS02030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GJE16_RS02040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GJE16_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
GJE16_RS02050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GJE16_RS02065	COG0439	Biotin carboxylase
GJE16_RS02070	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GJE16_RS02125	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GJE16_RS02130	COG1442	glycosyl transferase family 8
GJE16_RS02135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GJE16_RS02145	COG1461	Dihydroxyacetone kinase
GJE16_RS02150	COG0028	Belongs to the TPP enzyme family
GJE16_RS02155	COG0440	acetolactate synthase activity
GJE16_RS02175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GJE16_RS02190	COG0765	amino acid transport
GJE16_RS02210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GJE16_RS02215	COG1882	Formate acetyltransferase
GJE16_RS02240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GJE16_RS02245	COG0569	domain protein
GJE16_RS02265	COG1122	ATPase activity
GJE16_RS02280	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GJE16_RS02285	COG0671	phosphoesterase, PA-phosphatase related
GJE16_RS02305	COG0504	CTP synthase activity
GJE16_RS02310	COG1283	sodium-dependent phosphate transmembrane transporter activity
GJE16_RS02330	COG0789	Transcriptional regulator
GJE16_RS02335	COG0174	glutamine synthetase
GJE16_RS02355	COG4974	Belongs to the 'phage' integrase family
GJE16_RS02370	COG0732	type I restriction modification DNA specificity domain
GJE16_RS02415	COG0484	heat shock protein binding
GJE16_RS02430	COG0537	adenosine 5'-monophosphoramidase activity
GJE16_RS02435	COG1131	(ABC) transporter
GJE16_RS02460	COG3290	protein histidine kinase activity
GJE16_RS02470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJE16_RS02530	COG1266	CAAX protease self-immunity
GJE16_RS02550	COG0195	Participates in both transcription termination and antitermination
GJE16_RS02555	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GJE16_RS02620	COG0519	Catalyzes the synthesis of GMP from XMP
GJE16_RS02630	COG0525	valine-tRNA ligase activity
GJE16_RS02655	COG3711	transcriptional antiterminator
GJE16_RS02660	COG1263	PTS System
GJE16_RS02660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJE16_RS02660	COG2190	(PTS) system
GJE16_RS02675	COG0456	acetyltransferase
GJE16_RS02680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJE16_RS02680	COG0072	phenylalanine-tRNA ligase activity
GJE16_RS02695	COG3620	sequence-specific DNA binding
GJE16_RS02700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GJE16_RS02715	COG1045	serine acetyltransferase
GJE16_RS02725	COG0215	cysteine-tRNA ligase activity
GJE16_RS02730	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GJE16_RS02760	COG0577	efflux transmembrane transporter activity
GJE16_RS02765	COG1136	(ABC) transporter
GJE16_RS02770	COG0577	efflux transmembrane transporter activity
GJE16_RS02775	COG0745	RESPONSE REGULATOR receiver
GJE16_RS02780	COG5002	protein histidine kinase activity
GJE16_RS02785	COG0191	fructose-bisphosphate aldolase activity
GJE16_RS02795	COG0765	amino acid transport
GJE16_RS02800	COG0765	amino acid transport
GJE16_RS02805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJE16_RS02815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GJE16_RS02815	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GJE16_RS02855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJE16_RS02870	COG1573	uracil-dna glycosylase
GJE16_RS02880	COG1114	Component of the transport system for branched-chain amino acids
GJE16_RS02885	COG1363	Peptidase, m42
GJE16_RS02920	COG4555	ABC transporter
GJE16_RS02950	COG1404	Belongs to the peptidase S8 family
GJE16_RS02965	COG3775	system Galactitol-specific IIC component
GJE16_RS02970	COG3250	beta-galactosidase activity
GJE16_RS02990	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GJE16_RS03015	COG0785	Cytochrome C biogenesis protein
GJE16_RS03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJE16_RS03025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJE16_RS03025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJE16_RS03030	COG4753	response regulator
GJE16_RS03030	COG2207	Transcriptional regulator
GJE16_RS03035	COG2972	Histidine kinase
GJE16_RS03045	COG3064	Membrane
GJE16_RS03050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GJE16_RS03065	COG1940	carbohydrate kinase activity
GJE16_RS03085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GJE16_RS03090	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GJE16_RS03100	COG0300	oxidoreductase activity
GJE16_RS03125	COG1187	pseudouridine synthase activity
GJE16_RS03130	COG1217	gtp-binding protein TYPA
GJE16_RS03150	COG1136	(ABC) transporter
GJE16_RS03165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GJE16_RS03195	COG0284	orotidine-5'-phosphate decarboxylase activity
GJE16_RS03200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GJE16_RS03225	COG1131	(ABC) transporter
GJE16_RS03230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJE16_RS03235	COG1126	abc transporter atp-binding protein
GJE16_RS03240	COG0765	amino acid transport
GJE16_RS03245	COG0765	amino acid transport
GJE16_RS03250	COG1304	FMN binding
GJE16_RS03265	COG1304	FMN binding
GJE16_RS03285	COG0352	thiamine-phosphate diphosphorylase activity
GJE16_RS03295	COG4172	Belongs to the ABC transporter superfamily
GJE16_RS03305	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GJE16_RS03320	COG0352	thiamine-phosphate diphosphorylase activity
GJE16_RS03340	COG2217	Heavy metal translocating P-type atpase
GJE16_RS03345	COG0028	Belongs to the TPP enzyme family
GJE16_RS03360	COG2723	6-phospho-beta-galactosidase activity
GJE16_RS03365	COG1482	cell wall glycoprotein biosynthetic process
GJE16_RS03370	COG0733	neurotransmitter:sodium symporter activity
GJE16_RS03375	COG0789	Transcriptional regulator
GJE16_RS03390	COG2081	HI0933 family
GJE16_RS03395	COG1307	EDD domain protein, DegV family
GJE16_RS03405	COG2131	deaminase
GJE16_RS03410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GJE16_RS03450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GJE16_RS03450	COG0617	tRNA 3'-terminal CCA addition
GJE16_RS03450	COG0517	IMP dehydrogenase activity
GJE16_RS03460	COG2884	Cell division ATP-binding protein ftsE
GJE16_RS03465	COG2177	Part of the ABC transporter FtsEX involved in
GJE16_RS03470	COG2190	(PTS) system
GJE16_RS03470	COG1263	PTS System
GJE16_RS03470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJE16_RS03480	COG0513	Belongs to the DEAD box helicase family
GJE16_RS03490	COG0167	dihydroorotate dehydrogenase activity
GJE16_RS03500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GJE16_RS03505	COG4470	Protein conserved in bacteria
GJE16_RS03510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GJE16_RS03520	COG0488	(ABC) transporter
GJE16_RS03550	COG1837	Belongs to the UPF0109 family
GJE16_RS03575	COG1328	CTP reductase activity
GJE16_RS03575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GJE16_RS03585	COG4443	Transcriptional Coactivator p15 (PC4)
GJE16_RS03595	COG1268	BioY protein
GJE16_RS03610	COG0577	efflux transmembrane transporter activity
GJE16_RS03610	COG1136	(ABC) transporter
GJE16_RS03620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJE16_RS03625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GJE16_RS03630	COG1136	(ABC) transporter
GJE16_RS03635	COG0577	efflux transmembrane transporter activity
GJE16_RS03640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJE16_RS03640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJE16_RS03660	COG4989	oxidoreductase activity
GJE16_RS03670	COG1028	Short-chain dehydrogenase reductase Sdr
GJE16_RS03705	COG0745	RESPONSE REGULATOR receiver
GJE16_RS03710	COG5002	protein histidine kinase activity
GJE16_RS03730	COG0772	Belongs to the SEDS family
GJE16_RS03735	COG0693	protein deglycase activity
GJE16_RS03745	COG0187	DNA topoisomerase II activity
GJE16_RS03770	COG0494	nUDIX hydrolase
GJE16_RS03780	COG0542	response to heat
GJE16_RS03785	COG4703	Protein of unknown function (DUF1797)
GJE16_RS03790	COG0765	amino acid transport
GJE16_RS03795	COG1126	abc transporter atp-binding protein
GJE16_RS03800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GJE16_RS03805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GJE16_RS03825	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GJE16_RS03865	COG2813	Specifically methylates the guanine in position
GJE16_RS03870	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GJE16_RS03875	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GJE16_RS03880	COG0295	cytidine deaminase activity
GJE16_RS03885	COG1744	ABC transporter substrate-binding protein PnrA-like
GJE16_RS03890	COG3845	ABC transporter
GJE16_RS03895	COG4603	Belongs to the binding-protein-dependent transport system permease family
GJE16_RS03900	COG1079	Belongs to the binding-protein-dependent transport system permease family
GJE16_RS03915	COG0187	DNA topoisomerase II activity
GJE16_RS03920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GJE16_RS03925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GJE16_RS03930	COG4166	transmembrane transport
GJE16_RS03965	COG0539	negative regulation of cytoplasmic translation
GJE16_RS03975	COG1956	GAF domain-containing protein
GJE16_RS03980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GJE16_RS03995	COG0719	Fe-S assembly protein
GJE16_RS04000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GJE16_RS04010	COG0719	Fe-S assembly protein
GJE16_RS04015	COG1686	Belongs to the peptidase S11 family
GJE16_RS04020	COG0628	permease
GJE16_RS04035	COG1349	DNA-binding transcription factor activity
GJE16_RS04040	COG1105	Belongs to the carbohydrate kinase PfkB family
GJE16_RS04045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJE16_RS04045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJE16_RS04045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GJE16_RS04050	COG0697	spore germination
GJE16_RS04050	COG1674	ftsk spoiiie
GJE16_RS04060	COG1104	cysteine desulfurase activity
GJE16_RS04115	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GJE16_RS04120	COG1438	arginine binding
GJE16_RS04140	COG0469	pyruvate kinase activity
GJE16_RS04175	COG3689	TIGRFAM TIGR03943 family protein
GJE16_RS04180	COG0701	Predicted permease
GJE16_RS04195	COG2183	response to ionizing radiation
GJE16_RS04220	COG1136	(ABC) transporter
GJE16_RS04225	COG0577	efflux transmembrane transporter activity
GJE16_RS04245	COG1982	Orn Lys Arg decarboxylase major
GJE16_RS04255	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GJE16_RS04280	COG0561	phosphatase activity
GJE16_RS04300	COG0583	DNA-binding transcription factor activity
GJE16_RS04305	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GJE16_RS04310	COG0564	pseudouridine synthase activity
GJE16_RS04315	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GJE16_RS04330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GJE16_RS04340	COG0470	DNA polymerase III
GJE16_RS04385	COG0528	UMP kinase activity
GJE16_RS04395	COG2996	Protein conserved in bacteria
GJE16_RS04405	COG1702	phosphate starvation-inducible protein PhoH
GJE16_RS04425	COG0686	Belongs to the AlaDH PNT family
GJE16_RS04430	COG0686	Belongs to the AlaDH PNT family
GJE16_RS04435	COG0686	Belongs to the AlaDH PNT family
GJE16_RS04440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GJE16_RS04445	COG1596	polysaccharide export
GJE16_RS04445	COG1555	photosystem II stabilization
GJE16_RS04450	COG0658	competence protein
GJE16_RS04450	COG2333	competence protein COMEC
GJE16_RS04460	COG1131	(ABC) transporter
GJE16_RS04495	COG0543	2 iron, 2 sulfur cluster binding
GJE16_RS04500	COG0167	dihydroorotate dehydrogenase activity
GJE16_RS04505	COG4193	domain, Protein
GJE16_RS04505	COG5263	repeat protein
GJE16_RS04510	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GJE16_RS04520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GJE16_RS04530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GJE16_RS04535	COG0237	dephospho-CoA kinase activity
GJE16_RS04540	COG2814	Major facilitator Superfamily
GJE16_RS04545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GJE16_RS04555	COG0557	exoribonuclease II activity
GJE16_RS04565	COG3615	Tellurite resistance protein tehB
GJE16_RS04565	COG0500	methyltransferase
GJE16_RS04580	COG4122	O-methyltransferase activity
GJE16_RS04605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GJE16_RS04625	COG0494	nUDIX hydrolase
GJE16_RS04635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GJE16_RS04645	COG2176	DNA-directed DNA polymerase activity
GJE16_RS04650	COG0584	glycerophosphoryl diester phosphodiesterase
GJE16_RS04670	COG0785	Cytochrome C biogenesis protein
GJE16_RS04675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJE16_RS04680	COG0531	amino acid
GJE16_RS04685	COG0803	Belongs to the bacterial solute-binding protein 9 family
GJE16_RS04685	COG3443	Belongs to the bacterial solute-binding protein 9 family
GJE16_RS04730	COG1970	mechanosensitive ion channel activity
GJE16_RS04740	COG4708	membrane
GJE16_RS04750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GJE16_RS04760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GJE16_RS04765	COG1942	4-Oxalocrotonate Tautomerase
GJE16_RS04770	COG1435	thymidine kinase activity
GJE16_RS04780	COG2890	protein-(glutamine-N5) methyltransferase activity
GJE16_RS04805	COG0741	lytic transglycosylase activity
GJE16_RS04815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJE16_RS04835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJE16_RS04840	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJE16_RS04885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GJE16_RS04910	COG1597	lipid kinase activity
GJE16_RS04915	COG0366	Alpha amylase catalytic
GJE16_RS04925	COG1396	sequence-specific DNA binding
GJE16_RS04930	COG0542	response to heat
GJE16_RS04950	COG3843	relaxase mobilization nuclease domain protein
GJE16_RS04980	COG1131	(ABC) transporter
GJE16_RS05005	COG0772	Belongs to the SEDS family
GJE16_RS05010	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GJE16_RS05025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJE16_RS05030	COG0358	DNA primase activity
GJE16_RS05035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GJE16_RS05040	COG2151	metal-sulfur cluster biosynthetic enzyme
GJE16_RS05045	COG0438	transferase activity, transferring glycosyl groups
GJE16_RS05050	COG0438	transferase activity, transferring glycosyl groups
GJE16_RS05075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GJE16_RS05085	COG4109	DRTGG domain
GJE16_RS05090	COG0024	Methionine aminopeptidase
GJE16_RS05100	COG0210	DNA helicase
GJE16_RS05110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GJE16_RS05130	COG1104	cysteine desulfurase activity
GJE16_RS05135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GJE16_RS05145	COG2357	RelA SpoT domain protein
GJE16_RS05155	COG0564	pseudouridine synthase activity
GJE16_RS05160	COG0280	phosphate acetyltransferase
GJE16_RS05200	COG0196	riboflavin kinase activity
GJE16_RS05205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJE16_RS05210	COG1307	EDD domain protein, DegV family
GJE16_RS05220	COG0488	(ABC) transporter
GJE16_RS05230	COG2814	Major facilitator Superfamily
GJE16_RS05240	COG1523	belongs to the glycosyl hydrolase 13 family
GJE16_RS05245	COG1012	belongs to the aldehyde dehydrogenase family
GJE16_RS05255	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GJE16_RS05265	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GJE16_RS05295	COG0582	viral genome integration into host DNA
GJE16_RS05325	COG3583	domain protein
GJE16_RS05325	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GJE16_RS05330	COG3064	Membrane
GJE16_RS05335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GJE16_RS05355	COG0095	Lipoate-protein ligase
GJE16_RS05360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJE16_RS05365	COG0508	dehydrogenase complex catalyzes the overall conversion of
GJE16_RS05370	COG0022	dehydrogenase e1 component
GJE16_RS05375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GJE16_RS05380	COG0534	Mate efflux family protein
GJE16_RS05390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GJE16_RS05395	COG1051	belongs to the nudix hydrolase family
GJE16_RS05410	COG1011	Hydrolase
GJE16_RS05415	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GJE16_RS05430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJE16_RS05435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GJE16_RS05440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJE16_RS05445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GJE16_RS05460	COG2723	6-phospho-beta-galactosidase activity
GJE16_RS05475	COG3711	transcriptional antiterminator
GJE16_RS05480	COG3684	Belongs to the aldolase LacD family
GJE16_RS05530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GJE16_RS05535	COG0497	DNA recombination
GJE16_RS05540	COG1438	arginine binding
GJE16_RS05545	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GJE16_RS05575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GJE16_RS05595	COG3764	Sortase (surface protein transpeptidase)
GJE16_RS05600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GJE16_RS05630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GJE16_RS05635	COG5002	protein histidine kinase activity
GJE16_RS05640	COG0745	RESPONSE REGULATOR receiver
GJE16_RS05645	COG1194	a g-specific adenine glycosylase
GJE16_RS05660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GJE16_RS05665	COG4684	Psort location CytoplasmicMembrane, score
GJE16_RS05675	COG1827	regulation of RNA biosynthetic process
GJE16_RS05705	COG0765	amino acid transport
GJE16_RS05710	COG1126	abc transporter atp-binding protein
GJE16_RS05715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GJE16_RS05720	COG0552	protein localization to endoplasmic reticulum
GJE16_RS05725	COG0561	phosphatase activity
GJE16_RS05730	COG0561	phosphatase activity
GJE16_RS05735	COG1196	nuclear chromosome segregation
GJE16_RS05760	COG1401	restriction endodeoxyribonuclease activity
GJE16_RS05770	COG0066	3-isopropylmalate dehydratase activity
GJE16_RS05780	COG0473	3-isopropylmalate dehydrogenase activity
GJE16_RS05795	COG3142	Participates in the control of copper homeostasis
GJE16_RS05800	COG2832	Protein of unknown function (DUF454)
GJE16_RS05805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GJE16_RS05820	COG0758	DNA mediated transformation
GJE16_RS05825	COG4750	Nucleotidyl transferase
GJE16_RS05840	COG1063	alcohol dehydrogenase
GJE16_RS05845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GJE16_RS05855	COG3475	LICD family
GJE16_RS05860	COG3475	LICD family
GJE16_RS05870	COG0505	Belongs to the CarA family
GJE16_RS05885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GJE16_RS05900	COG0488	(ABC) transporter
GJE16_RS05910	COG1704	LemA family
GJE16_RS05925	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GJE16_RS05940	COG1078	dGTPase activity
GJE16_RS05960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJE16_RS05965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GJE16_RS05970	COG0077	Prephenate dehydratase
GJE16_RS05970	COG1605	Chorismate mutase
GJE16_RS05975	COG0716	FMN binding
GJE16_RS05980	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GJE16_RS06005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GJE16_RS06050	COG2081	HI0933 family
GJE16_RS06065	COG0395	ABC-type sugar transport system, permease component
GJE16_RS06070	COG4209	transmembrane transport
GJE16_RS06075	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GJE16_RS06105	COG0577	efflux transmembrane transporter activity
GJE16_RS06105	COG1136	(ABC) transporter
GJE16_RS06115	COG1770	oligopeptidase
GJE16_RS06125	COG0515	serine threonine protein kinase
GJE16_RS06150	COG0402	S-adenosylhomocysteine deaminase activity
GJE16_RS06165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJE16_RS06165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GJE16_RS06200	COG1215	transferase activity, transferring glycosyl groups
GJE16_RS06210	COG3475	LICD family
GJE16_RS06220	COG0077	Prephenate dehydratase
GJE16_RS06225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GJE16_RS06240	COG0287	Prephenate dehydrogenase
GJE16_RS06265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GJE16_RS06275	COG1131	(ABC) transporter
GJE16_RS06315	COG3842	ATPase activity
GJE16_RS06330	COG3527	Alpha-acetolactate decarboxylase
GJE16_RS06335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GJE16_RS06340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJE16_RS06345	COG0704	Plays a role in the regulation of phosphate uptake
GJE16_RS06350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJE16_RS06355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJE16_RS06360	COG0581	inorganic phosphate transmembrane transporter activity
GJE16_RS06365	COG0573	inorganic phosphate transmembrane transporter activity
GJE16_RS06370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GJE16_RS06375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GJE16_RS06375	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GJE16_RS06380	COG0483	inositol monophosphate 1-phosphatase activity
GJE16_RS06390	COG1393	Belongs to the ArsC family
GJE16_RS06400	COG0647	UMP catabolic process
GJE16_RS06410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GJE16_RS06430	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GJE16_RS06470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GJE16_RS06505	COG0826	peptidase U32
GJE16_RS06535	COG1132	(ABC) transporter
GJE16_RS06550	COG1129	ABC transporter
GJE16_RS06595	COG2188	Transcriptional regulator
GJE16_RS06600	COG0697	spore germination
GJE16_RS06605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GJE16_RS06620	COG0561	phosphatase activity
GJE16_RS06645	COG0492	ferredoxin-NADP+ reductase activity
GJE16_RS06655	COG1126	abc transporter atp-binding protein
GJE16_RS06665	COG1393	Belongs to the ArsC family
GJE16_RS06685	COG1272	protein, Hemolysin III
GJE16_RS06715	COG1053	succinate dehydrogenase
GJE16_RS06715	COG3976	FMN-binding domain protein
GJE16_RS06715	COG0431	NADPH-dependent FMN reductase
GJE16_RS06740	COG0656	L-ascorbic acid biosynthetic process
GJE16_RS06745	COG0726	polysaccharide deacetylase
GJE16_RS06790	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJE16_RS06825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GJE16_RS06835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GJE16_RS06840	COG1126	abc transporter atp-binding protein
GJE16_RS06850	COG0457	Tetratricopeptide repeat
GJE16_RS06855	COG0628	permease
GJE16_RS06860	COG2706	6-phosphogluconolactonase activity
GJE16_RS06925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GJE16_RS06950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GJE16_RS06955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GJE16_RS06960	COG0626	cystathionine gamma-synthase activity
GJE16_RS06965	COG1132	(ABC) transporter
GJE16_RS06975	COG4166	transmembrane transport
GJE16_RS06980	COG2244	polysaccharide biosynthetic process
GJE16_RS06985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GJE16_RS07010	COG2827	Endonuclease containing a URI domain
GJE16_RS07015	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GJE16_RS07020	COG1098	S1 RNA binding domain
GJE16_RS07030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GJE16_RS07035	COG0629	single-stranded DNA binding
GJE16_RS07045	COG0017	Asparaginyl-tRNA synthetase
GJE16_RS07055	COG0436	Aminotransferase
GJE16_RS07075	COG3711	transcriptional antiterminator
GJE16_RS07095	COG0242	peptide deformylase activity
GJE16_RS07100	COG0625	glutathione transferase activity
GJE16_RS07110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GJE16_RS07115	COG0488	(ABC) transporter
GJE16_RS07130	COG1307	EDD domain protein, DegV family
GJE16_RS07150	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GJE16_RS07170	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GJE16_RS07180	COG0251	oxidation-reduction process
GJE16_RS07200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GJE16_RS07210	COG4193	domain, Protein
GJE16_RS07210	COG5263	repeat protein
GJE16_RS07220	COG3935	DnaD domain protein
GJE16_RS07235	COG2226	methyltransferase
GJE16_RS07245	COG3842	ATPase activity
GJE16_RS07255	COG1335	isochorismatase
GJE16_RS07265	COG0513	Belongs to the DEAD box helicase family
GJE16_RS07270	COG2223	nitrite transmembrane transporter activity
GJE16_RS07275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GJE16_RS07280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJE16_RS07285	COG3442	glutamine amidotransferase
GJE16_RS07290	COG0006	proline dipeptidase activity
GJE16_RS07305	COG4720	Psort location CytoplasmicMembrane, score
GJE16_RS07310	COG0351	phosphomethylpyrimidine kinase
GJE16_RS07330	COG2824	Alkylphosphonate utilization operon protein PhnA
GJE16_RS07350	COG0463	Glycosyl transferase, family 2
GJE16_RS07355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJE16_RS07365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GJE16_RS07370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GJE16_RS07375	COG2384	SAM-dependent methyltransferase
GJE16_RS07380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GJE16_RS07385	COG0204	Acyl-transferase
GJE16_RS07400	COG2910	NAD(P)H-binding
GJE16_RS07435	COG5002	protein histidine kinase activity
GJE16_RS07440	COG0745	RESPONSE REGULATOR receiver
GJE16_RS07455	COG1959	2 iron, 2 sulfur cluster binding
GJE16_RS07520	COG3590	peptidase
GJE16_RS07535	COG0803	Belongs to the bacterial solute-binding protein 9 family
GJE16_RS07540	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GJE16_RS07550	COG1136	(ABC) transporter
GJE16_RS07550	COG0577	efflux transmembrane transporter activity
GJE16_RS07585	COG3599	regulation of cell shape
GJE16_RS07605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GJE16_RS07625	COG1051	belongs to the nudix hydrolase family
GJE16_RS07630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GJE16_RS07645	COG0768	penicillin binding
GJE16_RS07660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GJE16_RS07675	COG2731	YhcH YjgK YiaL family protein
GJE16_RS07680	COG0395	ABC-type sugar transport system, permease component
GJE16_RS07685	COG1175	transmembrane transport
GJE16_RS07695	COG2190	(PTS) system
GJE16_RS07695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJE16_RS07695	COG1263	PTS System
GJE16_RS07705	COG0673	inositol 2-dehydrogenase activity
GJE16_RS07710	COG4409	exo-alpha-(2->6)-sialidase activity
GJE16_RS07720	COG1175	transmembrane transport
GJE16_RS07725	COG1653	transport
GJE16_RS07745	COG3458	cephalosporin-C deacetylase activity
GJE16_RS07750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GJE16_RS07765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GJE16_RS07770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GJE16_RS07785	COG1131	(ABC) transporter
GJE16_RS07825	COG0778	Nitroreductase
GJE16_RS07830	COG1484	DNA-dependent DNA replication
GJE16_RS07845	COG1725	Transcriptional regulator
GJE16_RS07850	COG1131	(ABC) transporter
GJE16_RS07860	COG1668	transmembrane transport
GJE16_RS07865	COG4152	abc transporter atp-binding protein
GJE16_RS07885	COG1940	carbohydrate kinase activity
GJE16_RS07890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJE16_RS07890	COG1263	PTS System
GJE16_RS07890	COG2190	(PTS) system
GJE16_RS07895	COG1621	beta-fructofuranosidase activity
GJE16_RS07900	COG1609	Transcriptional regulator
GJE16_RS07910	COG3425	synthase
GJE16_RS07935	COG2815	serine threonine protein kinase
GJE16_RS07935	COG0515	serine threonine protein kinase
GJE16_RS07940	COG0631	protein serine/threonine phosphatase activity
GJE16_RS07945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GJE16_RS07945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GJE16_RS07955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GJE16_RS07965	COG0194	GDP metabolic process
GJE16_RS07985	COG2226	methyltransferase
GJE16_RS07990	COG0799	negative regulation of ribosome biogenesis
GJE16_RS08000	COG1713	HD superfamily hydrolase involved in NAD metabolism
GJE16_RS08005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GJE16_RS08010	COG1534	Rna-binding protein
GJE16_RS08015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GJE16_RS08030	COG0668	transmembrane transport
GJE16_RS08060	COG0438	transferase activity, transferring glycosyl groups
GJE16_RS08065	COG0438	transferase activity, transferring glycosyl groups
GJE16_RS08070	COG0653	protein targeting
GJE16_RS08090	COG0201	protein transport
GJE16_RS08095	COG1215	transferase activity, transferring glycosyl groups
GJE16_RS08100	COG1442	glycosyl transferase family 8
GJE16_RS08105	COG1442	glycosyl transferase family 8
GJE16_RS08110	COG1216	Glycosyl transferase, family 2
GJE16_RS08110	COG1442	glycosyl transferase family 8
GJE16_RS08115	COG1442	glycosyl transferase family 8
GJE16_RS08120	COG0438	transferase activity, transferring glycosyl groups
GJE16_RS08125	COG1442	glycosyl transferase family 8
GJE16_RS08125	COG1216	Glycosyl transferase, family 2
GJE16_RS08130	COG1442	glycosyl transferase family 8
GJE16_RS08135	COG1442	glycosyl transferase family 8
GJE16_RS08140	COG1442	glycosyl transferase family 8
GJE16_RS08140	COG1216	Glycosyl transferase, family 2
GJE16_RS08170	COG3118	belongs to the thioredoxin family
GJE16_RS08175	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GJE16_RS08185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJE16_RS08195	COG1164	Oligoendopeptidase f
GJE16_RS08200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GJE16_RS08210	COG1051	belongs to the nudix hydrolase family
GJE16_RS08245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GJE16_RS08255	COG1621	beta-fructofuranosidase activity
GJE16_RS08260	COG1653	transport
GJE16_RS08265	COG0395	ABC-type sugar transport system, permease component
GJE16_RS08270	COG4209	transmembrane transport
GJE16_RS08280	COG3711	transcriptional antiterminator
GJE16_RS08285	COG2261	transglycosylase associated protein
GJE16_RS08305	COG3237	CsbD-like
GJE16_RS08335	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJE16_RS08340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJE16_RS08350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJE16_RS08355	COG1846	Transcriptional regulator
GJE16_RS08355	COG1940	carbohydrate kinase activity
GJE16_RS08365	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GJE16_RS08385	COG0159	tryptophan synthase activity
GJE16_RS08395	COG0135	phosphoribosylanthranilate isomerase activity
GJE16_RS08410	COG0512	Glutamine amidotransferase of anthranilate synthase
GJE16_RS08415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GJE16_RS08435	COG1285	pathogenesis
GJE16_RS08440	COG1178	ABC-type Fe3 transport system permease component
GJE16_RS08460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GJE16_RS08465	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GJE16_RS08470	COG0704	Plays a role in the regulation of phosphate uptake
GJE16_RS08485	COG5434	Belongs to the glycosyl hydrolase 28 family
GJE16_RS08490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GJE16_RS08495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GJE16_RS08500	COG1132	(ABC) transporter
GJE16_RS08505	COG1132	(ABC) transporter
GJE16_RS08520	COG0708	Exodeoxyribonuclease III
GJE16_RS08540	COG2233	PERMEase
GJE16_RS08570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GJE16_RS08575	COG1609	Transcriptional regulator
GJE16_RS08580	COG1063	alcohol dehydrogenase
GJE16_RS08585	COG0789	Transcriptional regulator
GJE16_RS08590	COG1230	cation diffusion facilitator family transporter
GJE16_RS08600	COG3201	nicotinamide mononucleotide transporter
GJE16_RS08605	COG1174	glycine betaine transport
GJE16_RS08630	COG1363	Peptidase, m42
GJE16_RS08640	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GJE16_RS08645	COG4605	iron ion homeostasis
GJE16_RS08650	COG4604	ABC transporter, ATP-binding protein
GJE16_RS08655	COG4607	ABC-type enterochelin transport system periplasmic component
GJE16_RS08665	COG1187	pseudouridine synthase activity
GJE16_RS08685	COG0517	IMP dehydrogenase activity
GJE16_RS08695	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GJE16_RS08710	COG0366	Alpha amylase catalytic
GJE16_RS08715	COG1263	PTS System
GJE16_RS08715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJE16_RS08720	COG2188	Transcriptional regulator
GJE16_RS08725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GJE16_RS08730	COG4120	Belongs to the binding-protein-dependent transport system permease family
GJE16_RS08740	COG4608	Belongs to the ABC transporter superfamily
GJE16_RS08745	COG0444	Belongs to the ABC transporter superfamily
GJE16_RS08750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GJE16_RS08755	COG0601	transmembrane transport
GJE16_RS08760	COG4166	transmembrane transport
GJE16_RS08770	COG0366	Alpha amylase catalytic
GJE16_RS08775	COG0395	ABC-type sugar transport system, permease component
GJE16_RS08780	COG1175	transmembrane transport
GJE16_RS08785	COG1653	transport
GJE16_RS08790	COG3345	alpha-galactosidase
GJE16_RS08795	COG2207	Transcriptional regulator
GJE16_RS08800	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GJE16_RS08800	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GJE16_RS08920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GJE16_RS08960	COG4221	oxidoreductase activity
GJE16_RS08965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GJE16_RS08970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GJE16_RS09080	COG5263	repeat protein
GJE16_RS09080	COG5632	N-Acetylmuramoyl-L-alanine amidase
GJE16_RS09095	COG1546	Belongs to the CinA family
GJE16_RS09095	COG1058	Belongs to the CinA family
GJE16_RS09100	COG1316	TRANSCRIPTIONal
GJE16_RS09110	COG0802	atpase or kinase
GJE16_RS09130	COG1136	(ABC) transporter
GJE16_RS09130	COG0577	efflux transmembrane transporter activity
GJE16_RS09155	COG1253	flavin adenine dinucleotide binding
GJE16_RS09170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GJE16_RS09180	COG3480	Lon protease (S16) C-terminal proteolytic domain
GJE16_RS09190	COG0742	ribosomal rna small subunit methyltransferase
GJE16_RS09205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GJE16_RS09210	COG1254	Belongs to the acylphosphatase family
GJE16_RS09220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GJE16_RS09230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GJE16_RS09245	COG1564	THIamine pyrophosphokinase
GJE16_RS09255	COG1162	GTPase activity
GJE16_RS09290	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GJE16_RS09295	COG0084	hydrolase, TatD family'
GJE16_RS09315	COG0436	Aminotransferase
GJE16_RS09325	COG0589	response to stress
GJE16_RS09330	COG0561	phosphatase activity
GJE16_RS09335	COG0252	asparaginase activity
GJE16_RS09340	COG1609	Transcriptional regulator
GJE16_RS09345	COG2197	response regulator
GJE16_RS09350	COG4585	Histidine kinase
GJE16_RS09355	COG0842	Transport permease protein
GJE16_RS09360	COG1131	(ABC) transporter
GJE16_RS09470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GJE16_RS09475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJE16_RS09490	COG0577	efflux transmembrane transporter activity
GJE16_RS09500	COG0157	Belongs to the NadC ModD family
GJE16_RS09515	COG1129	ABC transporter
GJE16_RS09520	COG2188	Transcriptional regulator
GJE16_RS09525	COG2723	6-phospho-beta-galactosidase activity
GJE16_RS09530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GJE16_RS09540	COG1447	Phosphotransferase system cellobiose-specific component IIA
GJE16_RS09545	COG1454	alcohol dehydrogenase
GJE16_RS09545	COG1012	belongs to the aldehyde dehydrogenase family
GJE16_RS09555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GJE16_RS09565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GJE16_RS09585	COG3623	hexulose-6-phosphate isomerase
GJE16_RS09595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJE16_RS09605	COG3037	sugar-specific permease SgaT UlaA
GJE16_RS09615	COG1847	R3H domain protein
GJE16_RS09620	COG0706	membrane insertase activity
GJE16_RS09670	COG4537	Required for transformation and DNA binding
GJE16_RS09675	COG1459	type II secretion system
GJE16_RS09680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GJE16_RS09690	COG1063	alcohol dehydrogenase
GJE16_RS09715	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GJE16_RS09720	COG3759	membrane
GJE16_RS09735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GJE16_RS09735	COG0131	Imidazoleglycerol-phosphate dehydratase
GJE16_RS09740	COG0534	Mate efflux family protein
GJE16_RS09855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GJE16_RS09860	COG1132	(ABC) transporter
GJE16_RS09870	COG1132	(ABC) transporter
GJE16_RS09880	COG1438	arginine binding
GJE16_RS09900	COG0745	RESPONSE REGULATOR receiver
GJE16_RS09905	COG5002	protein histidine kinase activity
GJE16_RS09910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GJE16_RS09915	COG0573	inorganic phosphate transmembrane transporter activity
GJE16_RS09925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GJE16_RS09930	COG0704	Plays a role in the regulation of phosphate uptake
GJE16_RS09950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GJE16_RS09960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GJE16_RS09975	COG0697	spore germination
GJE16_RS09980	COG4499	WXG100 protein secretion system (Wss), protein YukC
GJE16_RS09980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GJE16_RS09990	COG2217	Heavy metal translocating P-type atpase
GJE16_RS10000	COG2226	methyltransferase
GJE16_RS10015	COG0058	SHG alpha-glucan phosphorylase activity
GJE16_RS10020	COG1640	4-alpha-glucanotransferase
GJE16_RS10025	COG2182	Extracellular solute-binding protein
GJE16_RS10030	COG1175	transmembrane transport
GJE16_RS10035	COG3833	ABC-type maltose transport systems, permease component
GJE16_RS10040	COG5521	maltodextrose utilization protein MalA
GJE16_RS10045	COG1609	Transcriptional regulator
GJE16_RS10055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GJE16_RS10085	COG1476	TRANSCRIPTIONal
GJE16_RS10115	COG2151	metal-sulfur cluster biosynthetic enzyme
GJE16_RS10130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GJE16_RS10135	COG3959	Transketolase, thiamine diphosphate binding domain
GJE16_RS10150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GJE16_RS10170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GJE16_RS10205	COG0383	alpha-mannosidase activity
GJE16_RS10215	COG3537	Alpha-1,2-mannosidase
GJE16_RS10235	COG0549	Belongs to the carbamate kinase family
GJE16_RS10240	COG1288	antiporter activity
GJE16_RS10245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GJE16_RS10255	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GJE16_RS10255	COG3064	Membrane
GJE16_RS10255	COG3583	domain protein
GJE16_RS10265	COG1454	alcohol dehydrogenase
GJE16_RS10285	COG3716	PTS system mannose fructose sorbose family IID component
GJE16_RS10295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GJE16_RS10315	COG1070	Carbohydrate kinase
GJE16_RS10325	COG3443	Belongs to the bacterial solute-binding protein 9 family
GJE16_RS10325	COG0803	Belongs to the bacterial solute-binding protein 9 family
GJE16_RS10330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GJE16_RS10335	COG1121	(ABC) transporter
GJE16_RS10340	COG1846	Transcriptional regulator
GJE16_RS10345	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GJE16_RS10355	COG1696	Membrane protein involved in D-alanine export
GJE16_RS10370	COG2211	Major facilitator Superfamily
GJE16_RS10375	COG3344	reverse transcriptase
GJE16_RS10390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GJE16_RS10395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GJE16_RS10415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GJE16_RS10425	COG1755	Isoprenylcysteine carboxyl methyltransferase
GJE16_RS10430	COG5002	protein histidine kinase activity
GJE16_RS10435	COG0745	RESPONSE REGULATOR receiver
GJE16_RS10440	COG0542	response to heat
GJE16_RS10445	COG4463	regulation of RNA biosynthetic process
GJE16_RS10450	COG1116	anion transmembrane transporter activity
GJE16_RS10455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GJE16_RS10460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GJE16_RS10480	COG0305	Participates in initiation and elongation during chromosome replication
GJE16_RS10500	COG1040	competence protein
GJE16_RS10505	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GJE16_RS10510	COG1739	Uncharacterized protein family UPF0029
GJE16_RS10550	COG3942	CHAP domain
GJE16_RS10560	COG1792	Involved in formation and maintenance of cell shape
GJE16_RS10565	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GJE16_RS10570	COG1122	ATPase activity
GJE16_RS10575	COG1122	ATPase activity
GJE16_RS10580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GJE16_RS10590	COG0612	Peptidase, M16
GJE16_RS10595	COG0612	Peptidase, M16
GJE16_RS10600	COG2501	S4 domain
GJE16_RS10610	COG0517	IMP dehydrogenase activity
GJE16_RS10610	COG0516	GMP reductase activity
GJE16_RS10615	COG0180	Tryptophanyl-tRNA synthetase
GJE16_RS10620	COG0488	(ABC) transporter
GJE16_RS10630	COG1511	domain protein
GJE16_RS10680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GJE16_RS10685	COG1475	DNA binding